glutamic acid and Central Nervous System Diseases

glutamic acid has been researched along with Central Nervous System Diseases in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19903 (7.89)18.7374
1990's9 (23.68)18.2507
2000's10 (26.32)29.6817
2010's13 (34.21)24.3611
2020's3 (7.89)2.80

Authors

AuthorsStudies
Blanc, M; Lesept, F; Potzeha, F; Seillier, C; Toutirais, O; Vivien, D1
Akanuma, SI1
Malinowski, B; Puk, O; Wiciński, M1
Eisenkraft, A; Falk, A; Finkelstein, A1
Lerma, J; Marques, JM1
Paoletti, P; Pin, JP1
Miladinovic, T; Nashed, MG; Singh, G1
Cioffi, CL; Guzzo, PR1
Koizumi, S; Shigetomi, E1
Brites, D; Fernandes, A1
Hamby, ME; Sofroniew, MV1
Feuerstein, TJ; Kammerer, M; Lücking, CH; Moser, A1
Brambilla, L; Martorana, F; Rossi, D1
Cavaletti, G; Slusher, B1
Kaplin, AI; Rahn, KA; Slusher, BS1
Matute, C; Ransom, BR1
Santello, M; Volterra, A1
Birnbaum, MJ; Chao, MV; Cho, H; Kim, AH; Margolis, B; Meyer, D; Monks, B; Yano, H1
OFFENHAMMER, K1
AMCHOVA-PRAZAKOVA, E; LESNY, I1
Begni, B; Beretta, S; Ferrarese, C1
Cooper, RR; Jones, KB; Mollano, AV; Morcuende, JA; Saltzman, CL1
Allen, NJ; Attwell, D; Káradóttir, R1
Benarroch, EE1
Platt, SR1
Alevra, X; Christodoulou, K; Georgiou, DM; Hadjisavvas, A; Kleopa, KA; Kyriakides, T; Nicolaou, P; Zamba-Papanicolaou, E1
McAdoo, DJ; Wu, P1
Barbeito, L; Estevez, AG; Stutzmann, JM1
Baraban, JM; Ratan, RR1
Meldrum, BS1
Akaoka, H; Belin, MF; Bernard, A; Didier-Bazes, M; Giraudon, P; Hardin-Pouzet, H1
Kempski, OS; Lowitzsch, K; Stover, JF1
Kempski, OS; Kossmann, T; Lowitzsch, K; Morganti-Kossmann, MC; Pleines, UE; Stover, JF1
Domercq, M; Fogarty, DJ; Matute, C; Pascual de Zulueta, M; Sánchez-Gómez, MV1
Abe, K; Hayashi, T; Manabe, Y; Murakami, T; Shoji, M; Wang, JM; Warita, H1
Brookes, N1
Olney, JW1
Boogaard, JS; Colton, JS; Dutka, AJ; Gilman, SC1

Reviews

26 review(s) available for glutamic acid and Central Nervous System Diseases

ArticleYear
Targeting NMDA Receptors at the Neurovascular Unit: Past and Future Treatments for Central Nervous System Diseases.
    International journal of molecular sciences, 2022, Sep-07, Volume: 23, Issue:18

    Topics: Central Nervous System Diseases; Glutamic Acid; Humans; Neurons; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission

2022
[Membrane Transporters and Their Regulatory Mechanisms at the Brain and Retinal Barriers to Establish Therapies for Refractory Central Nervous System Diseases].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2020, Volume: 140, Issue:10

    Topics: Animals; Biological Transport; Blood-Brain Barrier; Blood-Retinal Barrier; Brain; Central Nervous System Diseases; Connexin 43; Dinoprostone; Drug Development; Excitatory Amino Acid Transporter 1; Glutamic Acid; Humans; Membrane Transport Proteins; Mice; Molecular Targeted Therapy; Multidrug Resistance-Associated Proteins; Organic Anion Transporters, Sodium-Independent; Retina

2020
Cenobamate: Neuroprotective Potential of a New Antiepileptic Drug.
    Neurochemical research, 2021, Volume: 46, Issue:3

    Topics: Animals; Carbamates; Central Nervous System Diseases; Chlorophenols; Drug Repositioning; GABA-A Receptor Agonists; Glutamic Acid; Humans; Neuroprotective Agents; Signal Transduction; Tetrazoles; Voltage-Gated Sodium Channel Blockers

2021
The role of glutamate and the immune system in organophosphate-induced CNS damage.
    Neurotoxicity research, 2013, Volume: 24, Issue:2

    Topics: Adaptive Immunity; Animals; Central Nervous System Diseases; Glutamic Acid; Humans; Immunity, Innate; Immunologic Factors; Organophosphate Poisoning; Organophosphates

2013
Kainate receptors in health and disease.
    Neuron, 2013, Oct-16, Volume: 80, Issue:2

    Topics: Animals; Brain; Central Nervous System Diseases; Glutamic Acid; Health; Humans; Mental Disorders; Models, Neurological; Protein Binding; Receptors, Kainic Acid; Synaptic Transmission

2013
Overview of Glutamatergic Dysregulation in Central Pathologies.
    Biomolecules, 2015, Nov-11, Volume: 5, Issue:4

    Topics: Amino Acid Transport System X-AG; Animals; Central Nervous System Diseases; Glutamic Acid; Homeostasis; Humans; Receptors, Glutamate

2015
Inhibitors of Glycine Transporter-1: Potential Therapeutics for the Treatment of CNS Disorders.
    Current topics in medicinal chemistry, 2016, Volume: 16, Issue:29

    Topics: Central Nervous System Diseases; Glutamic Acid; Glycine Plasma Membrane Transport Proteins; Humans; Schizophrenia

2016
Visualization of diversity of calcium signals in astrocytes.
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2016, Volume: 148, Issue:2

    Topics: Adenosine Triphosphate; Animals; Astrocytes; Brain; Calcium; Calcium Signaling; Central Nervous System Diseases; Disease Models, Animal; Glutamic Acid; Mice; Molecular Imaging

2016
Contribution of inflammatory processes to nerve cell toxicity by bilirubin and efficacy of potential therapeutic agents.
    Current pharmaceutical design, 2009, Volume: 15, Issue:25

    Topics: Animals; Anti-Inflammatory Agents; Bilirubin; Cell Death; Cell Differentiation; Central Nervous System Diseases; Cytokines; Glutamic Acid; Humans; Hyperbilirubinemia; Hyperbilirubinemia, Neonatal; Immunologic Factors; Infant, Newborn; Inflammation; Inflammation Mediators; Kernicterus; Neurons; Neuroprotective Agents; Signal Transduction

2009
Reactive astrocytes as therapeutic targets for CNS disorders.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2010, Volume: 7, Issue:4

    Topics: Animals; Astrocytes; Central Nervous System Diseases; Cytokines; Enzyme Inhibitors; Free Radical Scavengers; Gene Expression Regulation; Glutamic Acid; Humans; Reactive Oxygen Species; Signal Transduction

2010
Selective GABA release as a mechanistic basis of high-frequency stimulation used for the treatment of neuropsychiatric diseases.
    Naunyn-Schmiedeberg's archives of pharmacology, 2011, Volume: 384, Issue:1

    Topics: Animals; Central Nervous System Diseases; Deep Brain Stimulation; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Mental Disorders

2011
Implications of gliotransmission for the pharmacotherapy of CNS disorders.
    CNS drugs, 2011, Volume: 25, Issue:8

    Topics: Animals; Astrocytes; Central Nervous System Agents; Central Nervous System Diseases; Drug Delivery Systems; Glutamic Acid; Humans; Neurodegenerative Diseases; Neuroglia; Signal Transduction

2011
Glutamate in CNS neurodegeneration and cognition and its regulation by GCPII inhibition.
    Current medicinal chemistry, 2012, Volume: 19, Issue:9

    Topics: Animals; Central Nervous System; Central Nervous System Diseases; Cognition; Enzyme Inhibitors; Glutamate Carboxypeptidase II; Glutamic Acid; Humans; Neuroprotective Agents; Synaptic Transmission

2012
Roles of white matter in central nervous system pathophysiologies.
    ASN neuro, 2012, Mar-22, Volume: 4, Issue:2

    Topics: Adenosine Triphosphate; Animals; Axons; Central Nervous System Diseases; Glutamic Acid; Humans; Nerve Fibers, Myelinated; Neuroglia; Neurotransmitter Agents; Signal Transduction

2012
TNFα in synaptic function: switching gears.
    Trends in neurosciences, 2012, Volume: 35, Issue:10

    Topics: Animals; Astrocytes; Central Nervous System; Central Nervous System Diseases; Glutamic Acid; Humans; Models, Biological; Neuronal Plasticity; Receptors, AMPA; Signal Transduction; Synaptic Transmission; Tumor Necrosis Factor-alpha

2012
Pharmacological manipulation of glutamate transport.
    Drug news & perspectives, 2003, Volume: 16, Issue:7

    Topics: Amino Acid Transport System X-AG; Animals; Central Nervous System Diseases; Glutamic Acid

2003
Bone and brain: a review of neural, hormonal, and musculoskeletal connections.
    The Iowa orthopaedic journal, 2004, Volume: 24

    Topics: Arthropathy, Neurogenic; Bone and Bones; Brain; Calcitonin Gene-Related Peptide; Catecholamines; Central Nervous System Diseases; Denervation; Glutamic Acid; Humans; Neuropeptides; Peripheral Nervous System Diseases; Substance P; Vasoactive Intestinal Peptide

2004
Reversal or reduction of glutamate and GABA transport in CNS pathology and therapy.
    Pflugers Archiv : European journal of physiology, 2004, Volume: 449, Issue:2

    Topics: Acute Disease; Animals; Central Nervous System Diseases; Chronic Disease; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Synaptic Transmission

2004
Neuron-astrocyte interactions: partnership for normal function and disease in the central nervous system.
    Mayo Clinic proceedings, 2005, Volume: 80, Issue:10

    Topics: Arginine Vasopressin; Astrocytes; Blood-Brain Barrier; Brain; Brain Edema; Cell Communication; Central Nervous System; Central Nervous System Diseases; Endothelium; Gap Junctions; Glutamic Acid; Hepatic Encephalopathy; Hydrogen-Ion Concentration; Membrane Microdomains; Neurons; Oxidative Stress; Seizures; Synaptic Transmission

2005
The role of glutamate in central nervous system health and disease--a review.
    Veterinary journal (London, England : 1997), 2007, Volume: 173, Issue:2

    Topics: Animal Diseases; Animals; Central Nervous System; Central Nervous System Diseases; Glutamic Acid; Receptors, Glutamate

2007
Microdialysis in central nervous system disorders and their treatment.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 90, Issue:2

    Topics: Animals; Brain Injuries; Calibration; Central Nervous System Diseases; Glutamic Acid; Hydroxyl Radical; Microdialysis; Neurons; Pain; Reactive Oxygen Species; Spinal Cord Injuries; Zinc

2008
Apoptotic death in an in vitro model of neuronal oxidative stress.
    Clinical and experimental pharmacology & physiology, 1995, Volume: 22, Issue:4

    Topics: Apoptosis; Cells, Cultured; Central Nervous System Diseases; Cystine; Free Radicals; Glutamic Acid; Glutathione; Humans; Neurons; Oxidative Stress; Reactive Oxygen Species

1995
The role of glutamate in epilepsy and other CNS disorders.
    Neurology, 1994, Volume: 44, Issue:11 Suppl 8

    Topics: Animals; Central Nervous System Diseases; Epilepsy; Glutamic Acid; Humans; Lamotrigine; Mice; N-Methylaspartate; Parkinson Disease; Piperazines; Pyrimidines; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Sodium Channels; Triazines

1994
Changes in astrocytic glutamate catabolism enzymes following neuronal degeneration or viral infection.
    Glia, 1997, Volume: 21, Issue:1

    Topics: Animals; Astrocytes; Brain; Central Nervous System Diseases; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamic Acid; Hippocampus; HTLV-I Infections; Humans; Nerve Degeneration; Neurons; Rats; Serotonin

1997
On how altered glutamate homeostasis may contribute to demyelinating diseases of the CNS.
    Advances in experimental medicine and biology, 1999, Volume: 468

    Topics: Animals; Cell Communication; Central Nervous System; Central Nervous System Diseases; Demyelinating Diseases; Glutamic Acid; Homeostasis; Humans; Synapses

1999
Excitotoxin-mediated neuron death in youth and old age.
    Progress in brain research, 1990, Volume: 86

    Topics: Aging; Alzheimer Disease; Amino Acids; Animals; Aspartic Acid; Brain Diseases, Metabolic; Brain Injuries; Calcium Channels; Cell Survival; Central Nervous System; Central Nervous System Diseases; Food; Food Additives; Glutamates; Glutamic Acid; Humans; Ion Channel Gating; Neurons; Neurotoxins; Rats; Receptors, N-Methyl-D-Aspartate

1990

Other Studies

12 other study(ies) available for glutamic acid and Central Nervous System Diseases

ArticleYear
Editorial overview: neurosciences: targeting glutamatergic signaling in CNS diseases: new hopes?
    Current opinion in pharmacology, 2015, Volume: 20

    Topics: Central Nervous System Diseases; Glutamic Acid; Humans; Neurosciences; Signal Transduction

2015
Regulation of glutamate synthesis via inhibition of glutamate carboxypeptidase II (GCPII): an effective method to treat central and peripheral nervous system disorders.
    Current medicinal chemistry, 2012, Volume: 19, Issue:9

    Topics: Animals; Central Nervous System; Central Nervous System Diseases; Enzyme Inhibitors; Glutamate Carboxypeptidase II; Glutamic Acid; Humans; Peripheral Nervous System; Peripheral Nervous System Diseases

2012
Akt1 regulates a JNK scaffold during excitotoxic apoptosis.
    Neuron, 2002, Aug-15, Volume: 35, Issue:4

    Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Arabidopsis Proteins; Carrier Proteins; Cell Survival; Cells, Cultured; Central Nervous System Diseases; Fetus; Gene Deletion; Gene Expression; Glutamic Acid; Hippocampus; Humans; JNK Mitogen-Activated Protein Kinases; Kainic Acid; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Neurons; Neurotoxins; Plant Proteins; Potassium Channels; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Signal Transduction

2002
[Glutamic acid in the treatment of central nervous disorders].
    Der Nervenarzt, 1952, Nov-20, Volume: 23, Issue:11

    Topics: Central Nervous System Diseases; Glutamates; Glutamic Acid

1952
[Determination of glutamic acid in the cerebrospinal fluid & its application in neurology].
    Ceskoslovenska neurologie, 1958, Volume: 21, Issue:4

    Topics: Central Nervous System Diseases; Cerebrospinal Fluid; Glutamates; Glutamic Acid; Humans; Neurology

1958
Phenotypic and cellular expression of two novel connexin32 mutations causing CMT1X.
    Neurology, 2006, Feb-14, Volume: 66, Issue:3

    Topics: Aged; Amino Acid Substitution; Central Nervous System Diseases; Charcot-Marie-Tooth Disease; Connexins; Demyelinating Diseases; Electromyography; Female; Gap Junction beta-1 Protein; Glutamic Acid; HeLa Cells; Humans; Leucine; Male; Middle Aged; Mutation, Missense; Neural Conduction; Pedigree; Phenotype; Polyneuropathies; Proline; Sural Nerve; Valine

2006
Protective effect of riluzole on excitatory amino acid-mediated neurotoxicity in motoneuron-enriched cultures.
    European journal of pharmacology, 1995, Jun-23, Volume: 280, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Survival; Cells, Cultured; Central Nervous System Diseases; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Kainic Acid; Motor Neurons; N-Methylaspartate; Rats; Receptors, Amino Acid; Riluzole; Thiazoles

1995
Cerebrospinal fluid hypoxanthine, xanthine and uric acid levels may reflect glutamate-mediated excitotoxicity in different neurological diseases.
    Neuroscience letters, 1997, Nov-28, Volume: 238, Issue:1-2

    Topics: Adult; Albumins; Central Nervous System Diseases; Cerebrovascular Disorders; Chromatography, High Pressure Liquid; Epilepsy; Female; Glutamic Acid; Humans; Hypoxanthine; L-Lactate Dehydrogenase; Lactic Acid; Male; Meningitis, Viral; Middle Aged; Multiple Sclerosis; Serum Albumin; Spinal Cord Diseases; Uric Acid; Xanthine

1997
Neurotransmitters in cerebrospinal fluid reflect pathological activity.
    European journal of clinical investigation, 1997, Volume: 27, Issue:12

    Topics: Adult; Aged; Asparagine; Aspartic Acid; Blood-Brain Barrier; Central Nervous System Diseases; Female; Glutamic Acid; Glutamine; Glycine; Humans; L-Lactate Dehydrogenase; Male; Middle Aged; Neurotransmitter Agents; Serine; Taurine

1997
Expressions of nitrotyrosine and TUNEL immunoreactivities in cultured rat spinal cord neurons after exposure to glutamate, nitric oxide, or peroxynitrite.
    Journal of neuroscience research, 2001, Sep-01, Volume: 65, Issue:5

    Topics: Animals; Antioxidants; Apoptosis; Cells, Cultured; Central Nervous System Diseases; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Free Radicals; Glutamic Acid; Immunohistochemistry; In Situ Nick-End Labeling; Interneurons; Motor Neurons; Nerve Degeneration; Neurons; Neurotoxins; Nitrates; Nitric Oxide Donors; Organ Culture Techniques; Oxidative Stress; Rats; Rats, Sprague-Dawley; Spinal Cord; Tyrosine

2001
In vitro evidence for the role of glutamate in the CNS toxicity of mercury.
    Toxicology, 1992, Dec-04, Volume: 76, Issue:3

    Topics: Animals; Astrocytes; Cell Survival; Cells, Cultured; Central Nervous System Diseases; Deoxyglucose; Extracellular Space; Glutamates; Glutamic Acid; Glutamine; Mercury; Mice; Models, Biological; Neurons; Photomicrography; Silver Staining; Spinal Cord; Tritium

1992
Effects of high pressure on the release of excitatory amino acids by brain synaptosomes.
    Undersea biomedical research, 1986, Volume: 13, Issue:4

    Topics: Animals; Aspartic Acid; Central Nervous System Diseases; Cerebral Cortex; Decompression; Glutamates; Glutamic Acid; Guinea Pigs; High Pressure Neurological Syndrome; Kinetics; Male; Neurotransmitter Agents; Synaptosomes; Tritium

1986