glutamic acid has been researched along with Cell Transformation, Neoplastic in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.45) | 18.7374 |
| 1990's | 5 (17.24) | 18.2507 |
| 2000's | 8 (27.59) | 29.6817 |
| 2010's | 14 (48.28) | 24.3611 |
| 2020's | 1 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Ding, Y; He, W; Hu, K; Jing, X; Wang, X; Yu, H; Zhu, H | 1 |
| Hanahan, D; Li, L | 1 |
| Botella, L; Callaghan, RC; Cerda-Nicolas, M; Gil-Benso, R; Gonzalez-Darder, J; Lopez-Gines, C; Muñoz-Hidalgo, L; Navarro, L; Quilis, V; San Miguel, T | 1 |
| Bjerkvig, R; Leenders, WP; Molenaar, R; Navis, AC; Niclou, SP; Tops, B; van Lith, SA; van Noorden, CJ; Verrijp, K; Wesseling, P | 1 |
| Casadei, GP; Cesari, V; Ciarrocchi, A; Cremonini, N; de Biase, D; Gandolfi, G; Pession, A; Ragazzi, M; Sancisi, V; Tallini, G; Visani, M | 1 |
| Bardeesy, N; Perera, RM | 1 |
| Chen, S; Goydos, JS; Shin, SS; Wall, BA | 1 |
| Goldin, R; Hanna, GB; Keun, HC; Yakoub, D | 1 |
| Hodin, R; Lawler, J; Nucera, C; Parangi, S | 1 |
| Chang, Q; Du, J; Li, Z; Liu, Y; Meline, B; Ranheim, E; Ryu, MJ; Tan, LX; Wang, J; Wang, Z; Young, KH; Zhang, J | 1 |
| Amato, MC; Bommarito, A; Carina, V; Carissimi, E; Criscimanna, A; Di Blasi, F; Galluzzo, A; Giordano, C; Latteri, MA; Modica, G; Pitrone, M; Pizzolanti, G; Richiusa, P; Rodolico, V; Spinelli, G; Zerilli, M; Zito, G | 1 |
| Chen, S; Teh, JL | 1 |
| Kung, HF; Lieberman, BP; Ploessl, K; Qu, W; Wang, L | 1 |
| Cao, J; Chen, C; Chen, W; Guo, HY; Han, ZX; Li, F; Li, ZY; Wang, XY; Wu, QY; Xu, KL; Zeng, LY; Zhao, K | 1 |
| Chen, S; Degenhardt, K; La Cava, SN; Martino, JJ; Mastrantoni, E; Wall, BA; White, E; Wilimczyk, BJ | 1 |
| Kaberlein, JJ; Luo, RT; Polak, PE; Simone, F; Thirman, MJ | 1 |
| Buscail, L; Cussac, D; Fourmy, D; Galés, C; Poirot, M; Pradayrol, L; Pyronnet, S; Sanchez, D; Silvente-Poirot, S | 1 |
| Alberghina, L; De Gioia, L; Fantinato, S; Fantucci, P; Manzoni, R; Metalli, D; Sacco, E; Vanoni, M | 1 |
| Driscoll, M; Friday, E; Turturro, F; Welbourne, T | 1 |
| Chikova, A; Dalal, S; DiMaio, D; Lang, T; Sweasy, JB | 1 |
| Cheung, M; Madhunapantula, SV; Robertson, GP; Sharma, A | 1 |
| Cowley, S; Kemp, P; Marshall, CJ; Paterson, H | 1 |
| Gallyas, F; Konishi, Y; Kunishita, T; Satoh, J; Tabira, T; Takeuchi, AM | 1 |
| Alberti, L; Bongarzone, I; Borrello, MG; Mondellini, P; Pasini, B; Pierotti, MA; Uggeri, M; Vigano, E | 1 |
| Genest, M; Sajot, N | 1 |
| Ajima, R; K-Tsuzuku, J; Nakamura, T; Suzuki, T; Yamamoto, T; Yoshida, Y | 1 |
| Countaway, JL; Davis, RJ; Nair, N; Robinson, HL; Taglienti-Sian, C; Theroux, SJ | 1 |
| Chu, CL; Leonard, M; Olmedo, R; Scher, BM; Scher, GS; Scher, W; Stecker, S; Waxman, S; Wu, H | 1 |
| Brandt-Rauf, PW; Chen, JM; Pincus, MR | 1 |
4 review(s) available for glutamic acid and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Glutamate as chemotactic fuel for diffuse glioma cells: are they glutamate suckers?
Topics: Animals; Brain Neoplasms; Cell Transformation, Neoplastic; Chemotaxis; Enzyme Inhibitors; Glioma; Glutamic Acid; Glutamine; Humans; Isocitrate Dehydrogenase | 2014 |
Pancreatic Cancer Metabolism: Breaking It Down to Build It Back Up.
Topics: Animals; Autophagy; Carcinoma, Pancreatic Ductal; Cell Transformation, Neoplastic; Energy Metabolism; Glucose; Glutamic Acid; Humans; Lipid Metabolism; Lysosomes; Molecular Targeted Therapy; Oxidation-Reduction; Pancreatic Neoplasms | 2015 |
The BRAFV600E mutation: what is it really orchestrating in thyroid cancer?
Topics: Amino Acid Substitution; Biomarkers, Tumor; Carcinoma; Carcinoma, Papillary; Cell Transformation, Neoplastic; Glutamic Acid; Humans; Models, Biological; Mutation, Missense; Proto-Oncogene Proteins B-raf; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Valine | 2010 |
Glutamatergic signaling in cellular transformation.
Topics: Animals; Brain; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Glutamic Acid; Humans; Melanocytes; Melanoma; Mice; Mice, Transgenic; Receptors, Metabotropic Glutamate; Signal Transduction; Skin Neoplasms | 2012 |
25 other study(ies) available for glutamic acid and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Glutamate dehydrogenase1 supports HIF-1α stability to promote colorectal tumorigenesis under hypoxia.
Topics: Carcinogenesis; Cell Hypoxia; Cell Line, Tumor; Cell Transformation, Neoplastic; Colorectal Neoplasms; Glutamic Acid; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit | 2023 |
Hijacking the neuronal NMDAR signaling circuit to promote tumor growth and invasion.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Glutamic Acid; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuroendocrine Tumors; Pancreatic Neoplasms; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Tumor Microenvironment | 2013 |
BRAF V600E mutation in two distinct meningeal melanocytomas associated with a nevus of Ota.
Topics: Adolescent; Cell Transformation, Neoplastic; Glutamic Acid; Humans; Male; Melanocytes; Melanoma; Meningeal Neoplasms; Mutation; Nevus of Ota; Proto-Oncogene Proteins B-raf; Signal Transduction; Skin Neoplasms; Valine | 2014 |
High-sensitivity BRAF mutation analysis: BRAF V600E is acquired early during tumor development but is heterogeneously distributed in a subset of papillary thyroid carcinomas.
Topics: Adult; Aged; Amino Acid Substitution; Carcinoma; Carcinoma, Papillary; Cell Transformation, Neoplastic; DNA Mutational Analysis; Gene Frequency; Genetic Heterogeneity; Glutamic Acid; Humans; Middle Aged; Polymerase Chain Reaction; Proto-Oncogene Proteins B-raf; Thyroid Cancer, Papillary; Thyroid Neoplasms; Valine; Young Adult | 2014 |
AKT2 is a downstream target of metabotropic glutamate receptor 1 (Grm1).
Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Enzyme Activation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glutamic Acid; Humans; Melanoma; Mice; Mice, Nude; Proto-Oncogene Proteins c-akt; Receptors, Metabotropic Glutamate; Signal Transduction; Skin Neoplasms | 2010 |
Metabolic profiling detects field effects in nondysplastic tissue from esophageal cancer patients.
Topics: Adenocarcinoma; Barrett Esophagus; Cell Transformation, Neoplastic; Diagnosis, Differential; Esophageal Neoplasms; Esophagus; Female; Glutamic Acid; Humans; Inosine; Inositol; Magnetic Resonance Spectroscopy; Male; Metabolome; Middle Aged; Mucous Membrane; Multivariate Analysis; Phosphorylcholine; Regression Analysis; Sensitivity and Specificity | 2010 |
Endogenous oncogenic Nras mutation initiates hematopoietic malignancies in a dose- and cell type-dependent manner.
Topics: Amino Acid Substitution; Animals; Aspartic Acid; Bone Marrow Transplantation; Cell Transformation, Neoplastic; Female; Gene Dosage; Genes, ras; Glutamic Acid; Hematologic Neoplasms; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Oncogenes; Organ Specificity | 2011 |
BRAFV600E mutation, TIMP-1 upregulation, and NF-κB activation: closing the loop on the papillary thyroid cancer trilogy.
Topics: Adult; Amino Acid Substitution; Carcinoma; Carcinoma, Papillary; Cell Transformation, Neoplastic; Disease Progression; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Glutamic Acid; Humans; Male; Middle Aged; Mutation, Missense; Neoplasm Invasiveness; NF-kappa B; Proto-Oncogene Proteins B-raf; Signal Transduction; Thyroid Cancer, Papillary; Thyroid Neoplasms; Tissue Inhibitor of Metalloproteinase-1; Tumor Cells, Cultured; Up-Regulation; Valine | 2011 |
Comparative evaluation of 18F-labeled glutamic acid and glutamine as tumor metabolic imaging agents.
Topics: Animals; Biological Transport; Cell Line, Tumor; Cell Transformation, Neoplastic; Fluorine Radioisotopes; Glutamic Acid; Glutamine; Humans; Male; Molecular Imaging; Radiochemistry; Rats; Stereoisomerism | 2012 |
Amino acid residue E543 in JAK2 C618R is a potential therapeutic target for myeloproliferative disorders caused by JAK2 C618R mutation.
Topics: Amino Acid Substitution; Animals; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Glutamic Acid; Humans; Janus Kinase 2; Mice; Models, Molecular; Mutagenesis, Site-Directed; Myeloproliferative Disorders; Point Mutation; Protein Conformation; Protein Refolding; Protein Unfolding | 2012 |
Metabotropic glutamate receptor 1 (Grm1) is an oncogene in epithelial cells.
Topics: Animals; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Enzyme Activation; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Glutamic Acid; Humans; Inositol 1,4,5-Trisphosphate; Mice; Mitogen-Activated Protein Kinases; Oncogenes; Phenotype; Proto-Oncogene Proteins c-akt; Receptors, Metabotropic Glutamate; Riluzole | 2013 |
ELL-associated factor 2 (EAF2), a functional homolog of EAF1 with alternative ELL binding properties.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Blotting, Northern; Bone Marrow; Cell Nucleus; Cell Transformation, Neoplastic; Conserved Sequence; DNA-Binding Proteins; Glutamic Acid; HeLa Cells; Hematopoietic Stem Cells; Histone-Lysine N-Methyltransferase; Humans; Immunosorbent Techniques; Leukemia, Myeloid, Acute; Mice; Molecular Sequence Data; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion; Peptide Fragments; Proto-Oncogenes; Recombinant Fusion Proteins; Retroviridae; Sequence Homology; Serine; Transcription Factors; Transcriptional Elongation Factors; Transfection | 2003 |
High tumorigenic potential of a constitutively active mutant of the cholecystokinin 2 receptor.
Topics: 3T3 Cells; Alanine; Amino Acid Motifs; Animals; Carcinogenicity Tests; Cell Division; Cell Transformation, Neoplastic; Enzyme Activation; Female; Glutamic Acid; Humans; Mice; Mice, Nude; Ornithine Decarboxylase; Point Mutation; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Type C Phospholipases | 2003 |
The isolated catalytic hairpin of the Ras-specific guanine nucleotide exchange factor Cdc25Mm retains nucleotide dissociation activity but has impaired nucleotide exchange activity.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Buffers; Catalysis; Catalytic Domain; Cell Line, Transformed; Cell Transformation, Neoplastic; Crystallography, X-Ray; Down-Regulation; Escherichia coli; Fibroblasts; Genes, Dominant; Genes, ras; Genes, Reporter; Glutamic Acid; Guanosine Diphosphate; Guanosine Triphosphate; Homozygote; Luciferases; Mice; Models, Molecular; Molecular Sequence Data; NIH 3T3 Cells; ortho-Aminobenzoates; Protein Structure, Secondary; ras-GRF1; Sequence Homology, Amino Acid; Temperature | 2005 |
ALK-mediated Na+/H+ exchanger-dependent intracellular alkalinization: does it matter for oncogenesis?
Topics: Alanine; Ammonia; Animals; Cell Division; Cell Line, Tumor; Cell Transformation, Neoplastic; Chromans; Culture Media, Conditioned; Drug Screening Assays, Antitumor; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Lymphoma, Large B-Cell, Diffuse; Mice; NIH 3T3 Cells; Protein-Tyrosine Kinases; Sodium-Hydrogen Exchangers; Thiazolidinediones; Transfection; Troglitazone | 2007 |
The E295K DNA polymerase beta gastric cancer-associated variant interferes with base excision repair and induces cellular transformation.
Topics: Animals; Cell Transformation, Neoplastic; DNA Polymerase beta; DNA Primers; DNA Repair; Embryo, Mammalian; Fibroblasts; Glutamic Acid; Humans; Lysine; Methyl Methanesulfonate; Mice; Mutant Proteins; Sister Chromatid Exchange; Stomach Neoplasms; Uracil | 2007 |
Akt3 and mutant V600E B-Raf cooperate to promote early melanoma development.
Topics: Animals; Cell Adhesion; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Chromones; Disease Progression; Glutamic Acid; Humans; MAP Kinase Signaling System; Melanocytes; Melanoma; Mice; Morpholines; Mutant Proteins; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Signal Transduction; Valine | 2008 |
Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells.
Topics: 3T3 Cells; Alanine; Animals; Cell Differentiation; Cell Division; Cell Line; Cell Transformation, Neoplastic; Culture Media, Serum-Free; DNA; Enzyme Activation; Glutamates; Glutamic Acid; Mice; Mitogen-Activated Protein Kinase Kinases; Mutation; Neurites; Neurons; PC12 Cells; Protein Kinase Inhibitors; Protein Kinases; Serine; Signal Transduction | 1994 |
Identifying monoaminergic, GABAergic, and cholinergic characteristics in immortalized neuronal cell lines.
Topics: Acetylcholine; Aging; Animals; Animals, Newborn; Aspartic Acid; Brain; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Cerebellum; Culture Media, Serum-Free; Dopamine; gamma-Aminobutyric Acid; Genes, myc; Glutamic Acid; Hippocampus; Hybrid Cells; Mice; Neuroblastoma; Neurons; Neurotransmitter Agents; Norepinephrine; PC12 Cells; Rats; Rhombencephalon; Serotonin | 1997 |
The Glu632-Leu633 deletion in cysteine rich domain of Ret induces constitutive dimerization and alters the processing of the receptor protein.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Cell Membrane; Cell Transformation, Neoplastic; Cysteine; Dimerization; Drosophila Proteins; Endoplasmic Reticulum; Glutamic Acid; Leucine; Mercaptoethanol; Mice; Phosphorylation; Polysaccharides; Precipitin Tests; Protein Precursors; Protein Processing, Post-Translational; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Sequence Deletion; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1 | 1999 |
Dimer interface of transmembrane domains for neu/erbB-2 receptor dimerization and transforming activation: a model revealed by molecular dynamics simulations.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cell Transformation, Neoplastic; Dimerization; Glutamic Acid; Humans; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Point Mutation; Protein Structure, Quaternary; Protein Structure, Tertiary; Receptor, ErbB-2; Thermodynamics | 2001 |
Phosphorylation of three regulatory serines of Tob by Erk1 and Erk2 is required for Ras-mediated cell proliferation and transformation.
Topics: 3T3 Cells; Alanine; Animals; Carrier Proteins; Cell Cycle; Cell Division; Cell Transformation, Neoplastic; Cyclin D1; Enzyme Inhibitors; Flavonoids; G1 Phase; Glutamic Acid; Glutamine; Glutathione Transferase; Intracellular Signaling Peptides and Proteins; Mice; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Peptide Mapping; Phosphorylation; Phosphoserine; Plasmids; Protein Structure, Tertiary; ras Proteins; Resting Phase, Cell Cycle; S Phase; Serine; Time Factors; Transfection | 2002 |
Increased oncogenic potential of ErbB is associated with the loss of a COOH-terminal domain serine phosphorylation site.
Topics: 3T3 Cells; Alanine; Animals; Cell Transformation, Neoplastic; Chick Embryo; Glutamates; Glutamic Acid; Kinetics; Mice; Mutation; Oncogenes; Phosphorylation; Plasmids; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptor, ErbB-2; Serine | 1992 |
Reduction in lactate accumulation correlates with differentiation-induced terminal cell division of leukemia cells.
Topics: Acetamides; Animals; Carbon Dioxide; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Dexamethasone; Dimethyl Sulfoxide; Glutamates; Glutamic Acid; Glutamine; Glycolysis; Humans; Lactates; Lactic Acid; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Mice | 1991 |
Conformational changes induced by the transforming amino acid substitution in the transmembrane domain of the neu oncogene-encoded p185 protein.
Topics: Amino Acid Sequence; Cell Membrane; Cell Transformation, Neoplastic; Glutamates; Glutamic Acid; Molecular Sequence Data; Oligopeptides; Protein Conformation; Proto-Oncogene Proteins; Receptor, ErbB-2; Structure-Activity Relationship; Thermodynamics; Valine | 1989 |