glutamic acid has been researched along with Cancer of the Thyroid in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.56) | 18.2507 |
| 2000's | 6 (15.38) | 29.6817 |
| 2010's | 28 (71.79) | 24.3611 |
| 2020's | 4 (10.26) | 2.80 |
| Authors | Studies |
|---|---|
| Hellmann, A; Korczynska, J; Mika, A; Taciak, A; Turyn, J; Zwara, A | 1 |
| Baba, HA; Bertram, S; Herold, T; Jastrow, H; Kälsch, J; Schaefer, CM; Schmid, KW; Schwertheim, S; Theurer, S; Ting, S; Westerwick, D | 1 |
| Chizhevskaya, SY; Kondakova, IV; Spirina, LV | 1 |
| Agarwal, S; Bal, C; Ballal, S; Chakraborty, D; Shakya, S | 1 |
| Buitrago, G; Castro, P; Fierro, F; Olaya, N; Patiño, E; Rojas, C | 1 |
| Ai, Z; Liu, W; Wang, C; Wang, Z | 1 |
| Asa, SL; Ezzat, S; Goldstein, DP; Mete, O; Perrier, L; Sawka, AM; Singarayer, R; Thabane, L; Van Uum, S | 1 |
| Boriskova, ME; Bykov, MA; Farafonova, UV; Pankova, PA; Saburova, IIu; Semënov, DIu; Zaraĭskiĭ, MI | 1 |
| Guan, H; Liu, R; Liu, X; Murugan, AK; Qu, S; Shan, Z; Sheng, C; Shi, X; Sun, H; Teng, W; Wang, Y; Xing, M; Yu, H; Zhu, G | 1 |
| Casadei, GP; Cesari, V; Ciarrocchi, A; Cremonini, N; de Biase, D; Gandolfi, G; Pession, A; Ragazzi, M; Sancisi, V; Tallini, G; Visani, M | 1 |
| Carman, CV; Chung, S; Clohessy, J; De Angelis, AM; Duquette, M; Durante, O; Dvorak, HF; Fadda, G; Farsetti, A; Fletcher, C; Henske, EP; Husain, A; Karreth, FA; Kutzner, H; Lawler, J; Lombardi, CP; Macconaill, LE; Martinelli, R; Mentzel, T; Nanni, S; Nucera, C; Palescandolo, E; Pandolfi, PP; Parker, JA; Pontecorvi, A; Priolo, C; Sadow, PM | 1 |
| Bishop, J; Du, J; El-Naggar, AK; Liu, R; Liu, X; Luo, Y; Qu, S; Shan, Z; Shi, X; Sun, H; Teng, W; Wang, E; Xing, M; Yang, X; Zhao, J; Zhu, G | 1 |
| Kang, G; Pyo, JS; Sohn, JH | 1 |
| Chmielik, E; Czarniecka, A; Handkiewicz-Junak, D; Jarzab, B; Jarzab, M; Kowal, M; Krajewska, J; Lange, D; Maciejewski, A; Oczko-Wojciechowska, M; Poltorak, S; Rusinek, D; Sacher, A; Stobiecka, E; Zebracka-Gala, J; Zembala-Nozynska, E | 1 |
| Bae, SK; Ha, TK; Jung, SJ; Kim, TH; Lee, SM; Park, JS; Urm, SH; Yoon, M | 1 |
| Choe, JH; Kim, JH; Kim, JS; Kim, SK; Lee, JH; Park, I; Woo, JW | 1 |
| Bouvet, M; Diaz-Perez, JA; Nguyen, QT; Orosco, RK; Savariar, EN; Tsien, RY; Weissbrod, PA | 1 |
| Xing, M; Zhang, T | 1 |
| Fukushima, M; Higashiyama, T; Hirokawa, M; Inoue, H; Ito, Y; Kihara, M; Kobayashi, K; Maruo, R; Matsuzuka, F; Miya, A; Miyauchi, A; Morita, S; Takamura, Y; Takano, T; Tomoda, C; Uruno, T; Yabuta, T; Yoshida, H | 1 |
| Buratto, M; Cavazzini, L; degli Uberti, EC; Frigato, G; Leoni, S; Rossi, R; Roti, E; Tagliati, F; Trasforini, G; Zatelli, MC | 1 |
| Baggiani, A; Basolo, F; Berti, P; Elisei, R; Giannini, R; Lupi, C; Miccoli, M; Miccoli, P; Sensi, E; Torregrossa, L; Vitti, P | 1 |
| Boriack, RL; Holt, SA; Kapur, P; Khokhar, S; Mitui, M; Rakheja, D | 1 |
| Hodin, R; Lawler, J; Nucera, C; Parangi, S | 1 |
| Hwang, TS; Jang, YM; Kim, DL; Kim, SK; Lee, EJ; Song, KH | 1 |
| Amato, MC; Bommarito, A; Carina, V; Carissimi, E; Criscimanna, A; Di Blasi, F; Galluzzo, A; Giordano, C; Latteri, MA; Modica, G; Pitrone, M; Pizzolanti, G; Richiusa, P; Rodolico, V; Spinelli, G; Zerilli, M; Zito, G | 1 |
| Hou, P; Liu, D; Xing, M | 1 |
| Liu, D; Liu, R; Xing, M | 1 |
| Budillon, A; Campanile, E; Fenzi, G; Forno, I; Fugazzola, L; Guerra, A; Marotta, V; Moccia, T; Rossi, S; Sapio, MR; Vitale, M | 1 |
| Chung, JH; Jang, JH; Ki, CS; Kim, JW; Kim, SW; Lee, ST; Oh, YL; Shin, JH | 1 |
| Beccati, MD; Bruni, S; Buratto, M; Degli Uberti, EC; Filieri, C; Rossi, M; Rossi, R; Tagliati, F; Trasforini, G; Zatelli, MC | 1 |
| Cameselle-Teijeiro, JM; Couto, JP; Faustino, A; Lopes, JM; Pardal, F; Pópulo, H; Rocha, AS; Soares, P; Sobrinho-Simões, M | 1 |
| Lee, KC; Li, C; Schneider, EB; Zeiger, MA | 1 |
| Agate, L; Basolo, F; Biagini, A; Elisei, R; Giannini, R; Lupi, C; Materazzi, G; Miccoli, P; Molinaro, E; Piaggi, P; Pinchera, A; Romei, C; Torregrossa, L; Ugolini, C; Valerio, L; Viola, D; Vitti, P | 1 |
| Caleo, A; Deandrea, M; Esposito, S; Fulciniti, F; Guerra, A; Limone, PP; Marotta, V; Motta, M; Vitale, M; Zeppa, P | 1 |
| Avenia, N; Cavaliere, A; Elisei, R; Fadda, G; Falorni, A; Marino, C; Martinelli, M; Moretti, S; Pacini, F; Pascucci, R; Pinchera, A; Pontecorvi, A; Puxeddu, E; Ribacchi, R; Romei, C; Rossi, ED; Santeusanio, F | 1 |
| Avenia, N; Beck-Peccoz, P; Bottici, V; Cavaliere, A; Cirello, V; Elisei, R; Faviana, P; Fugazzola, L; Mannavola, D; Moretti, S; Pacini, F; Pinchera, A; Puxeddu, E; Romei, C; Rossi, S; Santeusanio, F; Sculli, M | 1 |
| Hirokawa, M; Ito, Y; Miyauchi, A; Takano, T; Yoshida, H | 1 |
| Amato, MC; Cabibi, D; Galluzzo, A; Gebbia, N; Giordano, C; Martorana, A; Pizzolanti, G; Richiusa, P; Rodolico, V; Russo, A | 1 |
| Egawa, S; Futami, H; Kuma, K; Miyauchi, A; Obara, T; Yamaguchi, K | 1 |
4 review(s) available for glutamic acid and Cancer of the Thyroid
| Article | Year |
|---|---|
A Systematic Review and Meta-Analysis of the Diagnostic Performance of BRAF V600E Immunohistochemistry in Thyroid Histopathology.
Topics: Amino Acid Substitution; Biomarkers, Tumor; Cytodiagnosis; Diagnosis, Differential; Glutamic Acid; Humans; Immunohistochemistry; Mutation, Missense; Predictive Value of Tests; Prognosis; Proto-Oncogene Proteins B-raf; Sensitivity and Specificity; Thyroid Gland; Thyroid Neoplasms; Thyroid Nodule; Valine | 2019 |
BRAF Immunohistochemistry Using Clone VE1 is Strongly Concordant with BRAF(V600E) Mutation Test in Papillary Thyroid Carcinoma.
Topics: Amino Acid Substitution; Carcinoma; Carcinoma, Papillary; Cloning, Molecular; DNA Mutational Analysis; Glutamic Acid; Humans; Immunohistochemistry; Molecular Diagnostic Techniques; Mutation, Missense; Proto-Oncogene Proteins B-raf; Reproducibility of Results; Sensitivity and Specificity; Thyroid Cancer, Papillary; Thyroid Neoplasms; Valine | 2015 |
The BRAFV600E mutation: what is it really orchestrating in thyroid cancer?
Topics: Amino Acid Substitution; Biomarkers, Tumor; Carcinoma; Carcinoma, Papillary; Cell Transformation, Neoplastic; Glutamic Acid; Humans; Models, Biological; Mutation, Missense; Proto-Oncogene Proteins B-raf; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Valine | 2010 |
BRAF V600E mutation and its association with clinicopathological features of papillary thyroid cancer: a meta-analysis.
Topics: Age Factors; Amino Acid Substitution; Carcinoma; Carcinoma, Papillary; Female; Genetic Association Studies; Genetic Predisposition to Disease; Glutamic Acid; Humans; Lymphatic Metastasis; Male; Mutation, Missense; Proto-Oncogene Proteins B-raf; Sex Characteristics; Thyroid Cancer, Papillary; Thyroid Neoplasms; Tumor Burden; Valine | 2012 |
1 trial(s) available for glutamic acid and Cancer of the Thyroid
| Article | Year |
|---|---|
The BRAF(V600E) mutation is associated with malignant ultrasonographic features in thyroid nodules.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Biopsy, Fine-Needle; Carcinoma; Carcinoma, Papillary; Diagnosis, Differential; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Glutamic Acid; Humans; Male; Middle Aged; Mutation; Proto-Oncogene Proteins B-raf; Sensitivity and Specificity; Thyroid Cancer, Papillary; Thyroid Neoplasms; Thyroid Nodule; Ultrasonography; Valine; Young Adult | 2011 |
34 other study(ies) available for glutamic acid and Cancer of the Thyroid
| Article | Year |
|---|---|
Alterations in the amino acid profile in patients with papillary thyroid carcinoma with and without Hashimoto's thyroiditis.
Topics: Alanine; Amino Acids; Antibodies; Arginine; Glutamic Acid; Glycine; Hashimoto Disease; Humans; Lysine; Thyroid Cancer, Papillary; Thyroid Neoplasms; Tyrosine | 2023 |
New insights into intranuclear inclusions in thyroid carcinoma: Association with autophagy and with BRAFV600E mutation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Autophagy; Child; Female; Glutamic Acid; Humans; Immunohistochemistry; Intranuclear Inclusion Bodies; Male; Middle Aged; Mutation, Missense; Proto-Oncogene Proteins B-raf; Thyroid Cancer, Papillary; Thyroid Neoplasms; Tissue Array Analysis; Valine; Young Adult | 2019 |
Molecular Profiling of Follicular Variant of Papillary Thyroid Cancer.
Topics: Adult; Amino Acid Substitution; Carcinoma, Papillary, Follicular; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutamic Acid; Humans; Male; Middle Aged; Mutation, Missense; Proto-Oncogene Proteins B-raf; Signal Transduction; Thyroid Neoplasms; Valine | 2020 |
BRAF V600E and TERT promoter mutations in paediatric and young adult papillary thyroid cancer and clinicopathological correlation.
Topics: Adolescent; Adult; Age of Onset; Amino Acid Substitution; DNA Mutational Analysis; Female; Glutamic Acid; Humans; India; Male; Mutation, Missense; Prognosis; Promoter Regions, Genetic; Proto-Oncogene Proteins B-raf; Telomerase; Thyroid Cancer, Papillary; Thyroid Neoplasms; Valine; Young Adult | 2020 |
Clinical characteristics, surgical approach, BRAFV600E mutation and sodium iodine symporter expression in pediatric patients with thyroid carcinoma.
Topics: Adolescent; Age of Onset; Amino Acid Substitution; Child; Colombia; Female; Gene Expression Regulation, Neoplastic; Glutamic Acid; Humans; Incidence; Male; Mutation, Missense; Prognosis; Proto-Oncogene Proteins B-raf; Symporters; Thyroid Cancer, Papillary; Thyroid Neoplasms; Thyroidectomy; Treatment Outcome; Valine | 2020 |
CD133 promotes the self-renewal capacity of thyroid cancer stem cells through activation of glutamate aspartate transporter SLC1A3 expression.
Topics: AC133 Antigen; Cell Line, Tumor; Cell Self Renewal; Excitatory Amino Acid Transporter 1; Gene Expression Regulation, Neoplastic; Glutamic Acid; Humans; Neoplastic Stem Cells; Thyroid Neoplasms; Up-Regulation | 2019 |
[Use of BRAF V600E mutation in the differential diagnosis of follicular and papillary tumors of the thyroid and for the optimization of thearpy].
Topics: Adenocarcinoma, Follicular; Adult; Biopsy, Fine-Needle; Carcinoma, Papillary; Diagnosis, Differential; Female; Glutamic Acid; Goiter; Humans; Male; Middle Aged; Mutation; Proto-Oncogene Proteins B-raf; Sensitivity and Specificity; Thyroid Neoplasms; Valine | 2012 |
TERT promoter mutations and their association with BRAF V600E mutation and aggressive clinicopathological characteristics of thyroid cancer.
Topics: Adenocarcinoma, Follicular; Adult; Aged; Amino Acid Substitution; Base Sequence; Carcinoma; Carcinoma, Papillary; Cohort Studies; Female; Gene Frequency; Genetic Association Studies; Glutamic Acid; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation; Neoplasm Invasiveness; Promoter Regions, Genetic; Proto-Oncogene Proteins B-raf; Telomerase; Thyroid Cancer, Papillary; Thyroid Neoplasms; Valine | 2014 |
High-sensitivity BRAF mutation analysis: BRAF V600E is acquired early during tumor development but is heterogeneously distributed in a subset of papillary thyroid carcinomas.
Topics: Adult; Aged; Amino Acid Substitution; Carcinoma; Carcinoma, Papillary; Cell Transformation, Neoplastic; DNA Mutational Analysis; Gene Frequency; Genetic Heterogeneity; Glutamic Acid; Humans; Middle Aged; Polymerase Chain Reaction; Proto-Oncogene Proteins B-raf; Thyroid Cancer, Papillary; Thyroid Neoplasms; Valine; Young Adult | 2014 |
Role of BRAFV600E in the first preclinical model of multifocal infiltrating myopericytoma development and microenvironment.
Topics: Angiogenesis Inhibitors; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Genotype; Glutamic Acid; Hemangiopericytoma; Humans; Indoles; Mass Spectrometry; Mutation; Neoplasm Recurrence, Local; Pericytes; Proto-Oncogene Proteins B-raf; Sulfonamides; Thyroid Neoplasms; Valine; Vemurafenib; Xenograft Model Antitumor Assays | 2014 |
Association of TERT promoter mutation 1,295,228 C>T with BRAF V600E mutation, older patient age, and distant metastasis in anaplastic thyroid cancer.
Topics: Age Factors; Aged; Aged, 80 and over; Amino Acid Substitution; Epistasis, Genetic; Female; Genetic Association Studies; Glutamic Acid; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Proto-Oncogene Proteins B-raf; Telomerase; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Valine | 2015 |
The Risk of Relapse in Papillary Thyroid Cancer (PTC) in the Context of BRAFV600E Mutation Status and Other Prognostic Factors.
Topics: Adult; Amino Acid Substitution; Biomarkers, Tumor; Carcinoma; Carcinoma, Papillary; Female; Gene Frequency; Glutamic Acid; Humans; Male; Middle Aged; Mutation, Missense; Predictive Value of Tests; Prognosis; Proto-Oncogene Proteins B-raf; Recurrence; Risk Factors; Thyroid Cancer, Papillary; Thyroid Neoplasms; Valine | 2015 |
Relationships between transporter expression and the status of BRAF V600E mutation and F-18 FDG uptake in papillary thyroid carcinomas.
Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Carcinoma; Carcinoma, Papillary; Female; Fluorodeoxyglucose F18; Glucose Transporter Type 1; Glucose Transporter Type 3; Glutamic Acid; Humans; Immunohistochemistry; Male; Middle Aged; Mutation, Missense; Positron-Emission Tomography; Proto-Oncogene Proteins B-raf; Retrospective Studies; Thyroid Cancer, Papillary; Thyroid Neoplasms; Tomography, Emission-Computed; Valine; Young Adult | 2016 |
Chronic lymphocytic thyroiditis and BRAF V600E in papillary thyroid carcinoma.
Topics: Adult; Amino Acid Substitution; Carcinoma; Carcinoma, Papillary; Female; Glutamic Acid; Hashimoto Disease; Humans; Lymphatic Metastasis; Male; Middle Aged; Mutation, Missense; Prognosis; Proto-Oncogene Proteins B-raf; Retrospective Studies; Thyroid Cancer, Papillary; Thyroid Neoplasms; Valine | 2016 |
Molecular targeting of papillary thyroid carcinoma with fluorescently labeled ratiometric activatable cell penetrating peptides in a transgenic murine model.
Topics: Animals; Animals, Genetically Modified; Carcinoma; Carcinoma, Papillary; Cell-Penetrating Peptides; Disease Models, Animal; Fluorescence; Glutamic Acid; Laryngoscopy; Larynx; Mice; Molecular Targeted Therapy; Proto-Oncogene Proteins B-raf; Staining and Labeling; Thyroid Cancer, Papillary; Thyroid Neoplasms; Thyroidectomy; Treatment Outcome; Valine; Video Recording; Vocal Cords | 2016 |
HABP2 G534E Mutation in Familial Nonmedullary Thyroid Cancer.
Topics: Adult; Aged; Carcinoma; Carcinoma, Papillary; Female; Genetic Predisposition to Disease; Germ-Line Mutation; Glutamic Acid; Glycine; Humans; Male; Middle Aged; Prevalence; Serine Endopeptidases; Thyroid Cancer, Papillary; Thyroid Neoplasms | 2016 |
BRAF mutation in papillary thyroid carcinoma in a Japanese population: its lack of correlation with high-risk clinicopathological features and disease-free survival of patients.
Topics: Adult; Amino Acid Substitution; Carcinoma, Papillary; Disease-Free Survival; Female; Genetic Linkage; Genetic Predisposition to Disease; Genetics, Population; Glutamic Acid; Humans; Japan; Male; Middle Aged; Neoplasm Staging; Point Mutation; Prognosis; Proto-Oncogene Proteins B-raf; Risk Factors; Thyroid Neoplasms; Valine | 2009 |
BRAF V600E mutation analysis increases diagnostic accuracy for papillary thyroid carcinoma in fine-needle aspiration biopsies.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Biopsy, Fine-Needle; Carcinoma, Papillary; DNA Mutational Analysis; Female; Glutamic Acid; Humans; Male; Middle Aged; Polymorphism, Restriction Fragment Length; Proto-Oncogene Proteins B-raf; Sensitivity and Specificity; Thyroid Neoplasms; Valine; Young Adult | 2009 |
Correlation between the BRAF V600E mutation and tumor invasiveness in papillary thyroid carcinomas smaller than 20 millimeters: analysis of 1060 cases.
Topics: Adult; Amino Acid Substitution; Carcinoma, Papillary; Cohort Studies; Female; Genetic Predisposition to Disease; Glutamic Acid; Humans; Male; Middle Aged; Neoplasm Invasiveness; Point Mutation; Proto-Oncogene Proteins B-raf; Retrospective Studies; Thyroid Neoplasms; Tumor Burden; Valine | 2010 |
Papillary thyroid carcinoma shows elevated levels of 2-hydroxyglutarate.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Papillary; Case-Control Studies; Female; Glutamic Acid; Glutarates; Humans; Isocitrate Dehydrogenase; Ketoglutaric Acids; Male; Middle Aged; Mutation; Thyroid Gland; Thyroid Neoplasms; Thyroid Nodule | 2011 |
BRAFV600E mutation, TIMP-1 upregulation, and NF-κB activation: closing the loop on the papillary thyroid cancer trilogy.
Topics: Adult; Amino Acid Substitution; Carcinoma; Carcinoma, Papillary; Cell Transformation, Neoplastic; Disease Progression; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Glutamic Acid; Humans; Male; Middle Aged; Mutation, Missense; Neoplasm Invasiveness; NF-kappa B; Proto-Oncogene Proteins B-raf; Signal Transduction; Thyroid Cancer, Papillary; Thyroid Neoplasms; Tissue Inhibitor of Metalloproteinase-1; Tumor Cells, Cultured; Up-Regulation; Valine | 2011 |
Genome-wide alterations in gene methylation by the BRAF V600E mutation in papillary thyroid cancer cells.
Topics: Amino Acid Substitution; Carcinoma; Carcinoma, Papillary; Cluster Analysis; CpG Islands; DNA Methylation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Genome, Human; Glutamic Acid; Humans; Microarray Analysis; Mutation, Missense; Proto-Oncogene Proteins B-raf; Thyroid Cancer, Papillary; Thyroid Neoplasms; Tumor Cells, Cultured; Valine | 2011 |
The Akt inhibitor MK2206 synergizes, but perifosine antagonizes, the BRAF(V600E) inhibitor PLX4032 and the MEK1/2 inhibitor AZD6244 in the inhibition of thyroid cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Carcinoma; Cell Proliferation; Down-Regulation; Drug Antagonism; Drug Evaluation, Preclinical; Drug Synergism; Glutamic Acid; Heterocyclic Compounds, 3-Ring; Humans; Indoles; Mutant Proteins; Oncogene Protein v-akt; Phosphorylcholine; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Sulfonamides; Thyroid Neoplasms; Tumor Cells, Cultured; Valine; Vemurafenib | 2012 |
The primary occurrence of BRAF(V600E) is a rare clonal event in papillary thyroid carcinoma.
Topics: Amino Acid Substitution; Base Sequence; Carcinoma; Carcinoma, Papillary; Clone Cells; DNA Mutational Analysis; Gene Frequency; Glutamic Acid; Humans; Mutation, Missense; Proto-Oncogene Proteins B-raf; Retrospective Studies; Thyroid Cancer, Papillary; Thyroid Neoplasms; Tumor Cells, Cultured; Valine | 2012 |
Clinical implication of highly sensitive detection of the BRAF V600E mutation in fine-needle aspirations of thyroid nodules: a comparative analysis of three molecular assays in 4585 consecutive cases in a BRAF V600E mutation-prevalent area.
Topics: Adult; Amino Acid Substitution; Biopsy, Fine-Needle; Carcinoma; Carcinoma, Papillary; Cohort Studies; Cytological Techniques; DNA Mutational Analysis; Female; Gene Frequency; Glutamic Acid; Humans; Male; Middle Aged; Molecular Diagnostic Techniques; Mutation, Missense; Prevalence; Proto-Oncogene Proteins B-raf; Sensitivity and Specificity; Thyroid Cancer, Papillary; Thyroid Neoplasms; Thyroid Nodule; Valine | 2012 |
Role of ultrasonographic/clinical profile, cytology, and BRAF V600E mutation evaluation in thyroid nodule screening for malignancy: a prospective study.
Topics: Adult; Amino Acid Substitution; Biopsy, Fine-Needle; Carcinoma; Carcinoma, Papillary; Cytological Techniques; DNA Mutational Analysis; Early Detection of Cancer; Female; Glutamic Acid; Humans; Male; Middle Aged; Molecular Diagnostic Techniques; Mutation, Missense; Predictive Value of Tests; Prospective Studies; Proto-Oncogene Proteins B-raf; Retrospective Studies; Sensitivity and Specificity; Thyroid Cancer, Papillary; Thyroid Neoplasms; Thyroid Nodule; Ultrasonography, Interventional; Valine | 2012 |
mTOR pathway overactivation in BRAF mutated papillary thyroid carcinoma.
Topics: Amino Acid Substitution; Carcinoma; Carcinoma, Papillary; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Glutamic Acid; HEK293 Cells; Humans; Mutation, Missense; Proto-Oncogene Proteins B-raf; Serine; Signal Transduction; Thyroid Cancer, Papillary; Thyroid Neoplasms; TOR Serine-Threonine Kinases; Transfection; Up-Regulation; Valine | 2012 |
The BRAF(V600E) mutation is an independent, poor prognostic factor for the outcome of patients with low-risk intrathyroid papillary thyroid carcinoma: single-institution results from a large cohort study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Carcinoma; Carcinoma, Papillary; Cohort Studies; Female; Genetic Predisposition to Disease; Glutamic Acid; Humans; Male; Middle Aged; Mutation, Missense; Prognosis; Proto-Oncogene Proteins B-raf; Risk Factors; Sample Size; Thyroid Cancer, Papillary; Thyroid Gland; Thyroid Neoplasms; Valine; Young Adult | 2012 |
BRAF (V600E) associates with cytoplasmatic localization of p27kip1 and higher cytokeratin 19 expression in papillary thyroid carcinoma.
Topics: Amino Acid Substitution; Carcinoma; Carcinoma, Papillary; Cyclin-Dependent Kinase Inhibitor p27; Cytoplasm; Galectin 3; Gene Expression Regulation, Neoplastic; Gene Frequency; Glutamic Acid; Humans; Immunohistochemistry; Keratin-19; Proto-Oncogene Proteins B-raf; Thyroid Cancer, Papillary; Thyroid Neoplasms; Valine | 2013 |
BRAF(V599E) mutation is the leading genetic event in adult sporadic papillary thyroid carcinomas.
Topics: Adult; Aged; Blotting, Southern; Carcinoma, Papillary; Female; Gene Amplification; Glutamic Acid; Humans; Male; Middle Aged; Molecular Biology; Mutation; Nuclear Receptor Coactivators; Oncogene Proteins; Oncogene Proteins, Fusion; Protein-Tyrosine Kinases; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-raf; Reverse Transcriptase Polymerase Chain Reaction; Thyroid Neoplasms; Transcription Factors; Valine | 2004 |
Correlation between B-RAFV600E mutation and clinico-pathologic parameters in papillary thyroid carcinoma: data from a multicentric Italian study and review of the literature.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carcinoma, Papillary; DNA Mutational Analysis; Female; Glutamic Acid; Humans; Italy; Male; Middle Aged; Molecular Epidemiology; Point Mutation; Prevalence; Prognosis; Proto-Oncogene Proteins B-raf; Thyroid Neoplasms; Valine | 2006 |
BRAF V600E mutation in anaplastic thyroid carcinomas and their accompanying differentiated carcinomas.
Topics: Adult; Aged; Aged, 80 and over; Base Sequence; Carcinoma; Disease Progression; DNA Mutational Analysis; Female; Gene Frequency; Glutamic Acid; Humans; Male; Middle Aged; Models, Biological; Mutation, Missense; Proto-Oncogene Proteins B-raf; Thyroid Neoplasms; Valine | 2007 |
BRAF V600E mutation and p27 kip1 expression in papillary carcinomas of the thyroid
Topics: Adult; Biomarkers, Tumor; Carcinoma, Papillary; Cyclin-Dependent Kinase Inhibitor p27; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Glutamic Acid; Humans; Immunohistochemistry; Lymphatic Metastasis; Male; Middle Aged; Mutation; Polymerase Chain Reaction; Predictive Value of Tests; Prognosis; Proto-Oncogene Proteins B-raf; Sequence Analysis, DNA; Thyroid Neoplasms; Valine | 2007 |
A novel somatic mutation in the RET proto-oncogene in familial medullary thyroid carcinoma with a germline codon 768 mutation.
Topics: Aged; Amino Acid Sequence; Aspartic Acid; Base Sequence; Carcinoma, Medullary; Codon; Drosophila Proteins; Female; Glutamic Acid; Humans; Male; Middle Aged; Pedigree; Point Mutation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Proto-Oncogenes; Receptor Protein-Tyrosine Kinases; Thyroid Neoplasms | 1997 |