Compounds > glutamic acid

glutamic acid and Breast Neoplasms

glutamic acid has been researched along with Breast Neoplasms in 79 studies

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-19904 (5.06)18.7374
1990's4 (5.06)18.2507
2000's17 (21.52)29.6817
2010's40 (50.63)24.3611
2020's14 (17.72)2.80

Authors

AuthorsStudies
Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L1
Li, J; Lin, Y; Luo, Y; Qu, Z; Sun, Y; Yang, Z; Zhang, L; Zhang, X1
Chen, W; Hou, R; Li, Q; Liang, H; Yang, Y; Zhang, Y1
Abdellatif, AAH; Aldubayan, MA; Alhowail, AH; Almogbel, YS; Chigurupati, S; Nemala, RA1
Azahar, II; Che Has, AT; Jaafar, H; Mohd Nafi, SN; Mokhtar, NF; Noor Din, AHM; Sharudin, NA1
Bhattacharyya, M; Jariyal, H; Kumar, AS; Shah, RP; Srivastava, A; Thakkar, H1
Altwegg, KA; Chakravarty, D; Chen, Y; Ebrahimi, B; Huang, TH; Krishnan, S; Lai, Z; Li, X; Liu, J; Liu, Z; Ma, S; Mann, M; McHardy, S; Park, BH; Pratap, UP; Raj, GV; Rao, MK; Sanchez, JR; Santhamma, B; Sareddy, GR; Tekmal, RR; Vadlamudi, RK; Vankayalapati, H; Viswanadhapalli, S; Yuan, Y; Zhou, D1
El-Daly, SM; El-Toukhy, SE; Kamel, MM; Nabih, HK1
Gâz, ȘA; Lungu, IA; Moldovan, OL; Rusu, A; Sandulea, A1
Bejarbaneh, M; Jalali, A; Moradi-Shoeili, Z; Salehzadeh, A1
Xie, C; Yang, Y; Zhao, Y; Zhao, Z1
Chen, MC; Hsu, CY; Hsu, LL; Lee, HC; Tseng, LM; Wang, SF1
Albayrak, G; Bagriacik, EU; Bali, EB; Korkmaz, FD1
Chekkal, N; Hulea, L; Palia, R; Papadopoli, D; Pollak, M; St-Pierre, J; Topisirovic, I; Uchenunu, O1
Abbott, KL; Arevalo, OD; Coloff, JL; Dong, W; Ho, K; Hosios, AM; Iliopoulos, O; Keibler, MA; Kelleher, JK; Korthauer, KD; Lee, J; Liu, N; Moon, SJ; Phanse, AS; Stephanopoulos, G; Sullivan, LB; Vander Heiden, MG1
Ellis, JK; Keun, HC; Lam, EW; Lau, CE; Tredwell, GD1
Cavalli, LR; Fu, X; Grasso, CS; Győrffy, B; Heckler, MM; Klimach, U; Lewis, JA; Li, Z; Mahajan, A; Quist, MJ; Riggins, RB; Stires, H; Zwart, A1
Asara, JM; Geck, RC; Ghisolfi, L; Lien, EC; Toker, A1
Blyth, K; Dhayade, S; Dornier, E; Mackay, G; Macpherson, IR; Marco, S; Mitchell, L; Nixon, C; Norman, JC; Novo, D; Pallares, M; Rabas, N; Rainero, E; Sumpton, D1
An, Z; Anami, Y; Gui, X; Tsuchikama, K; Xiong, W; Yamazaki, CM; Zhang, N1
Chou, J; Liu, L; Wang, X; Yang, T; Yu, J; Zhang, F; Zhao, X1
Bellvert, F; Bertero, T; Boulter, E; Bourget, I; Bozec, A; Bulavin, DV; Chan, SY; Estrach, S; Feral, CC; Gaggioli, C; Grasset, EM; Hofman, P; Meneguzzi, G; Oldham, WM; Pisano, S1
Jain, S; Kumar, S; Paul, A; Raj, A; Roy, R; Singhai, A; Sonkar, AA1
Perry, RJ; Rabin-Court, A; Rodrigues, MR; Zhang, XM1
Chen, C; Cui, X; Guo, Z; Lin, D; Wang, S; Xie, C; Zhao, Y; Zhao, Z; Zhou, J1
Bacci, M; Bianchini, F; Cappellesso, F; Chiarugi, P; Comito, G; Ferracin, M; Gao, Q; Giannoni, E; Ippolito, L; Lorito, N; Luti, S; Marangoni, E; Martin, LA; Mazzone, M; Morandi, A; Parri, M; Ramazzotti, M; Romagnoli, S; Simões, BM; Virga, F1
Hanahan, D; Li, L1
Seidlitz, EP; Singh, G; Ungard, RG2
Chi, JT; Dewhirst, MW; Kennedy, KM; Landon, CD; Pizzo, S; Ribeiro, A; Richardson, R; Scarbrough, PM; Schroeder, T; Sonveaux, P; Yuan, H1
Foerster, B; Harris, RE; Ichesco, E; Khabir, T; Sen, A; Wood, L; Wright, B; Zick, SM; Zwickey, H1
Conti, PS; Fei, L; Shen, WC; Yap, LP; Zaro, JL1
Chan, MS; Dai, J; Guo, L; Liu, M; Ma, Y; Sasano, H; Shi, M; Wang, L; Wang, P; Wang, X; Zhang, Y1
Bahl, M; Barnes, T; Bell, K; Califaretti, N; Campbell, C; DiSebastiano, KM; Dubin, JA; Hanning, R; Mourtzakis, M; Russell, C; Vance, V1
Budczies, J; Denkert, C; Dietel, M; Fiehn, O; Györffy, B; Pfitzner, BM; Radke, C; Winzer, KJ1
Fazzari, J; Lin, H; Murphy, C; Singh, G; Ungard, R1
Habib, E; Lin, HX; Linher-Melville, K; Singh, G1
Gunning, P; Haftchenary, S; Linher-Melville, K; Singh, G1
Hemmati, M; Kazemi, B; Najafi, F; Shirkoohi, R; Zarebkohan, A1
Accart, N; Arigoni, M; Aurisicchio, L; Barrera, G; Bolli, E; Calogero, RA; Cavallo, F; Conti, L; Lanzardo, S; Macagno, M; Pizzimenti, S; Rooke, R; Ruiu, R1
Geck, RC; Toker, A1
Braun, CR; Brugge, JS; Coloff, JL; Gygi, SP; Harris, IS; Kami, K; Murphy, JP; Selfors, LM; Shelton, LM1
Deng, C; Meng, F; Wu, J; Zhang, J; Zhong, Z1
Backus, KM; Briggs, KJ; Cao, S; Clardy, J; Cravatt, BF; Gerfen, GJ; Kaelin, WG; Koivunen, P; Olenchock, BA; Patel, H; Richardson, AL; Signoretti, S; Witkiewicz, AK; Zhang, Q1
BassiriRad, NM; Bui, L; Doyle, T; Forte, BL; Largent-Milnes, TM; Mantyh, PW; Neumann, WL; Salvemini, D; Slosky, LM; Staatz, WD; Symons, AM; Thompson, M; Vanderah, TW1
Budczies, J1
Bartrons, R; Birbe, RC; Capparelli, C; Caro, J; Curry, JM; Domingo-Vidal, M; Ko, YH; Lin, Z; Manzano, A; Martinez-Outschoorn, U; Navarro-Sabaté, À; Roche, M; Seifert, E; Tassone, P; Tuluc, M; Whitaker-Menezes, D1
Di, X; Fu, Q; He, Z; Kan, Q; Li, L; Sun, J; Sun, Z; Wang, Y; Wu, M; Zhong, L1
Amari, T; Li, T; Semba, K; Takeoka, S; Yamamoto, T1
Kapoor, S; Kumar Santra, M; Naaz, A; Panda, D; Rai, A1
Armstrong, C; Giotopoulos, G; Osman, A; Peat, I; Symonds, RP; Talbot, CJ1
Moser, A; Thümen, A1
Kuroda, H; Kuroda, M; Saito, K; Suzuki, Y1
Barretina, J; Barrett, FG; Birsoy, K; Brachtel, EF; Chan, AM; Chen, WW; Cowley, GS; Driggers, EM; Garraway, LA; Hsu, PP; Jang, HG; Jha, AK; Kalaany, NY; Kim, D; Marks, KM; Mino-Kenudson, M; Ottina, K; Pacold, ME; Possemato, R; Root, DE; Sabatini, DM; Sethumadhavan, S; Shaul, YD; Stransky, N; Tsun, ZY; Woo, HK; Yuan, B1
Angeletti, RH; Berezniuk, I; Burd, B; Fricker, LD; Ikegami, K; Lyons, PJ; Setou, M; Sironi, JJ; Vu, HT; Xiao, H1
Oliver, J; Palou, A; Proenza, AM; Roca, P1
Carlberg, C; Frank, C; Lempiäinen, H; Matilainen, M; Molnár, F1
Balasenthil, S; Kumar, R; Mishra, SK; Nair, SS; Vadlamudi, RK; Yang, Z1
Bosio, A; Bullerdiek, J; Flohr, AM; Gerstmayer, B; Goldmann, T; Janssen, U; Loeschke, S; Murua Escobar, H; Vollmer, E1
Edwards, RA; Glover, JN; Lee, MS; Thede, GL1
Gao, J; Hu, Z; Jin, G; Liu, J; Qing, J; Shen, H; Wang, S; Wang, X; Zhai, X1
Galán, JJ; González-Mancha, R; González-Martín, A; Moreno-Nogueira, JA; Real, LM; Royo, JL; Ruiz, A1
Blanch, HW; Clark, DS; Forbes, NS; Meadows, AL1
Horwitz, SB; Wiesen, KM; Xia, S; Yang, CP1
Arnold, S; Brown, MA; Buchanan, D; Chenevix-Trench, G; Couch, FJ; Farrugia, DJ; Goldgar, DE; Healey, S; Henderson, BR; Lakhani, SR; Lovelock, PK; Mok, MT; Spurdle, AB; Tavtigian, SV1
Dyczynska, E; Sun, D; Syta, E; Zolkiewska, A1
Jeong, EG; Kim, MS; Lee, SH; Yoo, NJ1
Black, WR; Caldwell, RD; Case, LD; Cooper, MR; Cruz, JM; Jackson, DV; Muss, HB; Pope, EK; Wells, HB; White, DR1
Berns, CM; Corry, PM; Galoforo, SS; Guan, KL; Gupta, AK; Lee, YJ; Martinez, AA; Wu, X1
Abcouwer, SF; Collins, CL; Souba, WW; Wasa, M2
Berns, CM; Chen, JC; Corry, PM; Davis, BH; Galoforo, SS; Lee, YJ; Sim, JE; Spitz, DR1
Balraj, P; Khoo, AS; Nair, S; Volpi, L1
Pham, HT; Ruediger, R; Walter, G1
Aberg, F; Band Horwitz, S; Nieves, E; Orr, GA; Rao, S1
Davies, L; Friedlos, F; Marais, R; Martin, J; Niculescu-Duvaz, I; Ogilvie, LM; Scanlon, I; Spooner, RA; Springer, CJ; Stribbling, SM1
Degani, H; Neeman, M1
Jansen, S; Karner, J; Karner-Hanusch, J; Ollenschläger, G; Roth, E; Schindler, J1
Atkins, JN; Cruz, JM; Jackson, DV; Muss, HB; Richards, F; Wells, HB; White, DR; Zekan, PJ1

Reviews

3 review(s) available for glutamic acid and Breast Neoplasms

ArticleYear
Nonessential amino acid metabolism in breast cancer.
    Advances in biological regulation, 2016, Volume: 62

    Topics: Animals; Arginine; Breast Neoplasms; Cysteine; Diet Therapy; Female; Food Deprivation; Glutamic Acid; Glutamine; Glycine; Humans; Metabolic Networks and Pathways; Proline; Serine

2016
[Metabolome analysis of solid tumors].
    Der Pathologe, 2016, Volume: 37, Issue:Suppl 2

    Topics: 4-Aminobutyrate Transaminase; beta-Alanine; Biomarkers, Tumor; Breast; Breast Neoplasms; Colonic Neoplasms; Female; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Glutaminase; Glutamine; Humans; Metabolome; Neoplasms; Neoplasms, Hormone-Dependent; Ovarian Neoplasms; Ovary

2016
Oxidative stress and cancer pain.
    Canadian journal of physiology and pharmacology, 2013, Volume: 91, Issue:1

    Topics: Bone and Bones; Bone Neoplasms; Breast Neoplasms; Cysteine; Female; Glutamic Acid; Humans; Nociceptive Pain; Oxidative Stress; Reactive Oxygen Species

2013

Trials

1 trial(s) available for glutamic acid and Breast Neoplasms

ArticleYear
Amelioration of vincristine neurotoxicity by glutamic acid.
    The American journal of medicine, 1988, Volume: 84, Issue:6

    Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Constipation; Double-Blind Method; Female; Glutamates; Glutamic Acid; Humans; Mental Processes; Middle Aged; Nervous System; Paresthesia; Prospective Studies; Random Allocation; Reflex; Vincristine

1988

Other Studies

75 other study(ies) available for glutamic acid and Breast Neoplasms

ArticleYear
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
    Bioorganic & medicinal chemistry letters, 2013, Mar-15, Volume: 23, Issue:6

    Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship

2013
Effects of glutamate and aspartate on prostate cancer and breast cancer: a Mendelian randomization study.
    BMC genomics, 2022, Mar-16, Volume: 23, Issue:1

    Topics: Adult; Aspartic Acid; Breast Neoplasms; Glutamic Acid; Humans; Male; Mendelian Randomization Analysis; Prostatic Neoplasms

2022
An integrated metabonomics study to reveal the inhibitory effect and metabolism regulation of taurine on breast cancer.
    Journal of pharmaceutical and biomedical analysis, 2022, May-30, Volume: 214

    Topics: Animals; Arginine; Breast Neoplasms; Choline; Female; Glutamic Acid; Histidine; Humans; Isoleucine; Lactic Acid; Leucine; Lung Neoplasms; Metabolomics; Mice; Taurine; Valine

2022
Effects of CMF and MET on glutamate and dopamine levels in the brain, and their impact on cognitive function.
    European review for medical and pharmacological sciences, 2022, Volume: 26, Issue:7

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain; Breast Neoplasms; Cognition; Cyclophosphamide; Diabetes Mellitus, Type 2; Dopamine; Female; Fluorouracil; Glutamic Acid; Humans; Metformin; Methotrexate; Rats

2022
nNav1.5 expression is associated with glutamate level in breast cancer cells.
    Biological research, 2022, Apr-29, Volume: 55, Issue:1

    Topics: Breast Neoplasms; Cell Line, Tumor; Female; Glutamic Acid; Humans; Infant, Newborn; NAV1.5 Voltage-Gated Sodium Channel; RNA, Small Interfering

2022
Extrinsic hyaluronic acid induction differentially modulates intracellular glutamine metabolism in breast cancer stem cells.
    International journal of biological macromolecules, 2022, Oct-01, Volume: 218

    Topics: Breast Neoplasms; Cell Line, Tumor; Female; Glutamic Acid; Glutamine; Humans; Hyaluronic Acid; Neoplastic Stem Cells; Reactive Oxygen Species

2022
A First-in-Class Inhibitor of ER Coregulator PELP1 Targets ER+ Breast Cancer.
    Cancer research, 2022, 10-17, Volume: 82, Issue:20

    Topics: Breast Neoplasms; Cell Line, Tumor; Co-Repressor Proteins; Estrogen Receptor alpha; Estrogens; Female; Glutamic Acid; Humans; Leucine; Proline; Proteasome Endopeptidase Complex; Receptors, Estrogen; Transcription Factors

2022
The diagnostic significance of circulating miRNAs and metabolite profiling in early prediction of breast cancer in Egyptian women.
    Journal of cancer research and clinical oncology, 2023, Volume: 149, Issue:8

    Topics: Biomarkers, Tumor; Breast Neoplasms; Circulating MicroRNA; Disease Progression; Egypt; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutamic Acid; Humans; MicroRNAs; Tandem Mass Spectrometry

2023
Identification of Some Glutamic Acid Derivatives with Biological Potential by Computational Methods.
    Molecules (Basel, Switzerland), 2023, May-16, Volume: 28, Issue:10

    Topics: Amino Acids; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Female; Glutamic Acid; Glutamine; Humans; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship

2023
Synthesis of Cobalt Hydroxide Nano-flakes Functionalized with Glutamic Acid and Conjugated with Thiosemicarbazide for Anticancer Activities Against Human Breast Cancer Cells.
    Biological trace element research, 2020, Volume: 198, Issue:1

    Topics: Breast Neoplasms; Cobalt; Female; Glutamic Acid; Humans; Hydroxides; Semicarbazides; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction

2020
Dual-targeting liposome modified by glutamic hexapeptide and folic acid for bone metastatic breast cancer.
    Chemistry and physics of lipids, 2020, Volume: 228

    Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Female; Folic Acid; Glutamic Acid; Humans; Ligands; Liposomes; Oligopeptides; Rats; Wound Healing

2020
ROS Mediate xCT-Dependent Cell Death in Human Breast Cancer Cells under Glucose Deprivation.
    Cells, 2020, 07-01, Volume: 9, Issue:7

    Topics: Acetylcysteine; Amino Acid Transport System y+; AMP-Activated Protein Kinase Kinases; Antineoplastic Agents; Antioxidants; Breast Neoplasms; Cell Death; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glucose; Glutamic Acid; Glutathione; Humans; Ketoglutaric Acids; Protein Kinases; Reactive Oxygen Species; RNA, Small Interfering; Sirtuin 3; Sulfasalazine; Up-Regulation

2020
Antitumorigenic Effect of Memantine via Interfering Glutamate Metabolism in Mouse 4T1 Breast Tumor Model.
    Anti-cancer agents in medicinal chemistry, 2021, Volume: 21, Issue:12

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Proliferation; Disease Models, Animal; Drug Screening Assays, Antitumor; Female; Glutamic Acid; Memantine; Mice; Mice, Inbred BALB C; Tumor Cells, Cultured

2021
Perturbations of cancer cell metabolism by the antidiabetic drug canagliflozin.
    Neoplasia (New York, N.Y.), 2021, Volume: 23, Issue:4

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Canagliflozin; Cell Line, Tumor; Cell Proliferation; Cell Respiration; Citric Acid Cycle; Diabetes Mellitus, Type 2; Female; Glucose; Glutamate Dehydrogenase; Glutamic Acid; Humans; MCF-7 Cells; Mice; Mitochondria; Oxygen Consumption; RNA Interference; RNA, Small Interfering; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors

2021
Differential substrate use in EGF- and oncogenic KRAS-stimulated human mammary epithelial cells.
    The FEBS journal, 2021, Volume: 288, Issue:19

    Topics: Animals; Breast; Breast Neoplasms; Carcinogenesis; Cell Proliferation; Epidermal Growth Factor; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Glucose; Glucose Transporter Type 1; Glutamic Acid; Glutamine; Humans; Lactic Acid; Mammary Glands, Human; Proto-Oncogene Proteins p21(ras); Tumor Cells, Cultured

2021
Metabolomic characterisation of the effects of oncogenic PIK3CA transformation in a breast epithelial cell line.
    Scientific reports, 2017, 04-10, Volume: 7

    Topics: Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Citric Acid Cycle; Class I Phosphatidylinositol 3-Kinases; Epithelial Cells; Female; Glutamic Acid; Glycerylphosphorylcholine; Humans; Lipids; Metabolome; Metabolomics; Models, Biological; Mutation; Proton Magnetic Resonance Spectroscopy; Pyruvates

2017
Integrated molecular analysis of Tamoxifen-resistant invasive lobular breast cancer cells identifies MAPK and GRM/mGluR signaling as therapeutic vulnerabilities.
    Molecular and cellular endocrinology, 2018, 08-15, Volume: 471

    Topics: Breast Neoplasms; Carcinoma, Lobular; Cell Line, Tumor; Drug Resistance, Neoplasm; Exome Sequencing; Female; Gene Amplification; Gene Expression Regulation, Neoplastic; Glutamic Acid; Hepatocyte Nuclear Factor 3-alpha; Humans; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mutation; Protein Kinase Inhibitors; Receptors, Estrogen; Receptors, Metabotropic Glutamate; Signal Transduction; Tamoxifen; Transcriptome

2018
Oncogenic PI3K promotes methionine dependency in breast cancer cells through the cystine-glutamate antiporter xCT.
    Science signaling, 2017, Dec-19, Volume: 10, Issue:510

    Topics: Amino Acid Transport System y+; Breast Neoplasms; Carcinogenesis; Cell Line; Cell Proliferation; Class I Phosphatidylinositol 3-Kinases; Cysteine; Cystine; Female; Gene Expression; Glutamic Acid; Homocysteine; Humans; Mammary Glands, Human; MCF-7 Cells; Methionine; Mutation

2017
Glutaminolysis drives membrane trafficking to promote invasiveness of breast cancer cells.
    Nature communications, 2017, 12-21, Volume: 8, Issue:1

    Topics: Amino Acid Transport System y+; Animals; Breast Neoplasms; Cell Line, Tumor; Extracellular Space; Female; Glutamic Acid; Glutamine; Homeostasis; Humans; Mammary Glands, Human; Mammary Neoplasms, Animal; Matrix Metalloproteinase 14; Mice; Neoplasm Invasiveness; rab27 GTP-Binding Proteins; Receptors, Metabotropic Glutamate; Up-Regulation

2017
Glutamic acid-valine-citrulline linkers ensure stability and efficacy of antibody-drug conjugates in mice.
    Nature communications, 2018, 06-28, Volume: 9, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Breast Neoplasms; Carboxylic Ester Hydrolases; Cell Line, Tumor; Citrulline; Drug Design; Drug Stability; Female; Gene Expression; Glutamic Acid; Humans; Hydrolysis; Immunoconjugates; Mice; Mice, Inbred BALB C; Mice, Nude; Oligopeptides; Receptor, ErbB-2; Survival Analysis; Valine; Xenograft Model Antitumor Assays

2018
Taurine, glutamic acid and ethylmalonic acid as important metabolites for detecting human breast cancer based on the targeted metabolomics.
    Cancer biomarkers : section A of Disease markers, 2018, Volume: 23, Issue:2

    Topics: Adult; Biomarkers; Breast Neoplasms; Chromatography, High Pressure Liquid; Female; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Humans; Malonates; Metabolome; Metabolomics; Middle Aged; Reproducibility of Results; ROC Curve; Tandem Mass Spectrometry; Taurine

2018
Tumor-Stroma Mechanics Coordinate Amino Acid Availability to Sustain Tumor Growth and Malignancy.
    Cell metabolism, 2019, 01-08, Volume: 29, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Animals; Aspartic Acid; Breast Neoplasms; Cancer-Associated Fibroblasts; Carcinoma; Cell Line; Extracellular Matrix; Female; Glutamic Acid; Head and Neck Neoplasms; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Trans-Activators; Transcription Factors; Transcriptional Coactivator with PDZ-Binding Motif Proteins; YAP-Signaling Proteins

2019
Alteration in lipid composition differentiates breast cancer tissues: a
    Metabolomics : Official journal of the Metabolomic Society, 2018, 09-03, Volume: 14, Issue:9

    Topics: Breast Neoplasms; Choline; Female; Glutamic Acid; Glycine; Humans; Lipids; Metabolomics; Middle Aged; Multivariate Analysis; Proton Magnetic Resonance Spectroscopy; Taurine

2018
Obesity-associated, but not obesity-independent, tumors respond to insulin by increasing mitochondrial glucose oxidation.
    PloS one, 2019, Volume: 14, Issue:6

    Topics: Alanine; Breast Neoplasms; Cell Line, Tumor; Citrate (si)-Synthase; Colonic Neoplasms; Female; Gene Expression Regulation; Glucose; Glutamic Acid; Humans; Insulin; Isotope Labeling; Ketone Oxidoreductases; Lymphoma, B-Cell; Male; Melanoma; Mitochondria; Obesity; Organ Specificity; Oxidation-Reduction; Phosphorylation; Prostatic Neoplasms; Receptor, Insulin; Signal Transduction; Skin Neoplasms; Small Cell Lung Carcinoma

2019
Dual-active targeting liposomes drug delivery system for bone metastatic breast cancer: Synthesis and biological evaluation.
    Chemistry and physics of lipids, 2019, Volume: 223

    Topics: Animals; Antineoplastic Agents, Phytogenic; Bone Neoplasms; Breast Neoplasms; Cell Proliferation; Drug Delivery Systems; Drug Screening Assays, Antitumor; Female; Glutamic Acid; Humans; Ligands; Liposomes; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Oligopeptides; Paclitaxel; Tumor Cells, Cultured

2019
Reprogramming of Amino Acid Transporters to Support Aspartate and Glutamate Dependency Sustains Endocrine Resistance in Breast Cancer.
    Cell reports, 2019, 07-02, Volume: 28, Issue:1

    Topics: Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Aspartic Acid; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Excitatory Amino Acid Transporter 2; Female; Gas Chromatography-Mass Spectrometry; GATA2 Transcription Factor; Gene Expression Regulation, Neoplastic; Glutamic Acid; Humans; Mice; Mice, Inbred BALB C; MicroRNAs; Neoplasm Metastasis; Prognosis; Transcriptome; Transplantation, Heterologous

2019
Hijacking the neuronal NMDAR signaling circuit to promote tumor growth and invasion.
    Cell, 2013, Mar-28, Volume: 153, Issue:1

    Topics: Adenocarcinoma; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Glutamic Acid; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuroendocrine Tumors; Pancreatic Neoplasms; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Tumor Microenvironment

2013
Inhibition of breast cancer-cell glutamate release with sulfasalazine limits cancer-induced bone pain.
    Pain, 2014, Volume: 155, Issue:1

    Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Bone and Bones; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Humans; Mice; Mice, Nude; Pain; Pain Measurement; Sulfasalazine; Survival Analysis; Xenograft Model Antitumor Assays

2014
Catabolism of exogenous lactate reveals it as a legitimate metabolic substrate in breast cancer.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Adult; Aged; Alanine; Animals; Breast Neoplasms; Cell Death; Cell Hypoxia; Cell Line, Tumor; Coumaric Acids; Disease Models, Animal; Female; Glucose; Glutamic Acid; Humans; Kinetics; Lactic Acid; Metabolic Networks and Pathways; Metabolomics; Middle Aged; Neoplasm Staging; Rats

2013
Preliminary differences in peripheral immune markers and brain metabolites between fatigued and non-fatigued breast cancer survivors: a pilot study.
    Brain imaging and behavior, 2014, Volume: 8, Issue:4

    Topics: Aspartic Acid; Biomarkers; Brain; Breast Neoplasms; Creatine; Cross-Sectional Studies; Fatigue; Female; Glutamic Acid; Glutamine; Humans; Interleukin-6; Middle Aged; Phosphocreatine; Pilot Projects; Prognosis; Proton Magnetic Resonance Spectroscopy; Sensitivity and Specificity; Severity of Illness Index; Survivors

2014
Tumor targeting of a cell penetrating peptide by fusing with a pH-sensitive histidine-glutamate co-oligopeptide.
    Biomaterials, 2014, Volume: 35, Issue:13

    Topics: Animals; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell-Penetrating Peptides; Drug Delivery Systems; Female; Glutamic Acid; Glutathione Transferase; HeLa Cells; Histidine; Humans; Hydrogen-Ion Concentration; Mice; Xenograft Model Antitumor Assays

2014
The pattern of proline, glutamic acid, and leucine-rich protein 1 expression in Chinese women with primary breast cancer.
    The International journal of biological markers, 2014, Mar-24, Volume: 29, Issue:1

    Topics: Biomarkers, Tumor; Breast Neoplasms; China; Co-Repressor Proteins; Female; Gene Expression Regulation, Neoplastic; Glutamic Acid; Humans; Prognosis; Proline; Transcription Factors; Treatment Outcome

2014
Plasma amino acid profiles of breast cancer patients early in the trajectory of the disease differ from healthy comparison groups.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2014, Volume: 39, Issue:6

    Topics: Adolescent; Adult; Amino Acids; Body Composition; Breast Neoplasms; Case-Control Studies; Energy Intake; Female; Glutamic Acid; Glutamine; Histidine; Humans; Leucine; Middle Aged; Threonine

2014
Glutamate enrichment as new diagnostic opportunity in breast cancer.
    International journal of cancer, 2015, Apr-01, Volume: 136, Issue:7

    Topics: Biomarkers; Breast Neoplasms; Case-Control Studies; Cluster Analysis; Female; Gene Expression Profiling; Glutamic Acid; Glutamine; Humans; Lymphatic Metastasis; Metabolomics; Neoplasm Grading; Neoplasm Staging; Peroxisome Proliferator-Activated Receptors; Prognosis; Receptors, Estrogen; Signal Transduction

2015
Inhibitors of glutamate release from breast cancer cells; new targets for cancer-induced bone-pain.
    Scientific reports, 2015, Feb-11, Volume: 5

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Bone and Bones; Breast Neoplasms; Capsaicin; Cell Line, Tumor; Dopamine Agonists; Drug Discovery; Female; Glutamic Acid; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Pain; Signal Transduction; Small Molecule Libraries

2015
Expression of xCT and activity of system xc(-) are regulated by NRF2 in human breast cancer cells in response to oxidative stress.
    Redox biology, 2015, Volume: 5

    Topics: Amino Acid Transport System y+; Breast Neoplasms; Cell Nucleus; Female; Gene Expression Regulation, Neoplastic; Glutamic Acid; Glutathione; Humans; Hydrogen Peroxide; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; MCF-7 Cells; NF-E2-Related Factor 2; Oxidative Stress; Promoter Regions, Genetic; Protein Subunits; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Up-Regulation

2015
Signal transducer and activator of transcription 3 and 5 regulate system Xc- and redox balance in human breast cancer cells.
    Molecular and cellular biochemistry, 2015, Volume: 405, Issue:1-2

    Topics: Breast Neoplasms; Cell Line, Tumor; Cystine; Female; Glutamic Acid; Glutathione; Humans; Oxidation-Reduction; Promoter Regions, Genetic; Reactive Oxygen Species; RNA, Messenger; RNA, Small Interfering; Signal Transduction; STAT3 Transcription Factor; STAT5 Transcription Factor; Transcriptional Activation; Tumor Suppressor Proteins; Up-Regulation

2015
Synthesis and evaluation of a glutamic acid-modified hPAMAM complex as a promising versatile gene carrier.
    Journal of drug targeting, 2016, Volume: 24, Issue:5

    Topics: Breast Neoplasms; Cell Line, Tumor; Dendrimers; DNA; Female; Gene Transfer Techniques; Genetic Therapy; Glutamic Acid; Humans; Lipids; MCF-7 Cells; Polyamines; Transfection

2016
Immunotargeting of Antigen xCT Attenuates Stem-like Cell Behavior and Metastatic Progression in Breast Cancer.
    Cancer research, 2016, Jan-01, Volume: 76, Issue:1

    Topics: Amino Acid Transport Systems; Animals; Antigens, Neoplasm; Breast Neoplasms; Cancer Vaccines; Cell Line, Tumor; Cystine; Disease Progression; Female; Glutamic Acid; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Knockout; Neoplastic Stem Cells; NIH 3T3 Cells; Up-Regulation; Vaccines, DNA; Xenograft Model Antitumor Assays

2016
Differential Glutamate Metabolism in Proliferating and Quiescent Mammary Epithelial Cells.
    Cell metabolism, 2016, 05-10, Volume: 23, Issue:5

    Topics: Breast Neoplasms; Cell Proliferation; Cells, Cultured; Epithelial Cells; Female; Glutamate Dehydrogenase; Glutamic Acid; Humans; Mammary Glands, Human; Metabolomics; Models, Biological; Nitrogen Isotopes; Phosphatidylinositol 3-Kinases; Proteomics; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases; Transaminases

2016
Vitamin E-Oligo(methyl diglycol l-glutamate) as a Biocompatible and Functional Surfactant for Facile Preparation of Active Tumor-Targeting PLGA Nanoparticles.
    Biomacromolecules, 2016, 07-11, Volume: 17, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biocompatible Materials; Breast Neoplasms; Cell Survival; Drug Carriers; Drug Delivery Systems; Female; Glutamic Acid; Glycols; Humans; Lactic Acid; Mice; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface-Active Agents; Tumor Cells, Cultured; Vitamin E; Xenograft Model Antitumor Assays

2016
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine.
    Cell, 2016, Jun-30, Volume: 166, Issue:1

    Topics: Amino Acid Transport System y+; Animals; Breast Neoplasms; Cysteine; Glutamic Acid; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Inducible Factor-Proline Dioxygenases; MCF-7 Cells; Mice; Paracrine Communication; Triple Negative Breast Neoplasms

2016
The cystine/glutamate antiporter system xc- drives breast tumor cell glutamate release and cancer-induced bone pain.
    Pain, 2016, Volume: 157, Issue:11

    Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antiporters; Bone Neoplasms; Breast Neoplasms; Calcium-Binding Proteins; Cancer Pain; Cell Line, Tumor; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Glutamic Acid; Heterografts; Metalloporphyrins; Mice; Mice, Inbred BALB C; Peroxynitrous Acid; Sulfasalazine; Time Factors

2016
TP53-inducible Glycolysis and Apoptosis Regulator (TIGAR) Metabolically Reprograms Carcinoma and Stromal Cells in Breast Cancer.
    The Journal of biological chemistry, 2016, Dec-16, Volume: 291, Issue:51

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Coculture Techniques; Female; Fibroblasts; Glutamic Acid; Glycolysis; Humans; Intracellular Signaling Peptides and Proteins; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; MCF-7 Cells; Phosphofructokinase-2; Phosphoric Monoester Hydrolases; Tumor Suppressor Protein p53

2016
Targeting tumor highly-expressed LAT1 transporter with amino acid-modified nanoparticles: Toward a novel active targeting strategy in breast cancer therapy.
    Nanomedicine : nanotechnology, biology, and medicine, 2017, Volume: 13, Issue:3

    Topics: Animals; Antineoplastic Agents; Breast; Breast Neoplasms; Drug Carriers; Drug Delivery Systems; Female; Glutamic Acid; HeLa Cells; Humans; Lactic Acid; Large Neutral Amino Acid-Transporter 1; MCF-7 Cells; Mice; Mice, Inbred BALB C; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer

2017
Construction and evaluation of pH-sensitive immunoliposomes for enhanced delivery of anticancer drug to ErbB2 over-expressing breast cancer cells.
    Nanomedicine : nanotechnology, biology, and medicine, 2017, Volume: 13, Issue:3

    Topics: Animals; Antineoplastic Agents; Breast; Breast Neoplasms; Delayed-Action Preparations; Doxorubicin; Female; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Immunoconjugates; Immunoglobulin Fab Fragments; Liposomes; Mice; Mice, Inbred BALB C; Mice, Nude; Receptor, ErbB-2

2017
Enhanced stability of microtubules contributes in the development of colchicine resistance in MCF-7 cells.
    Biochemical pharmacology, 2017, 05-15, Volume: 132

    Topics: Acetylation; Breast Neoplasms; Colchicine; Drug Resistance, Neoplasm; Glutamic Acid; Humans; MCF-7 Cells; Microtubules; Mutation; Paclitaxel; Tubulin

2017
Refining the evidence for GSTA1 and eNOS genetic effects on risk of radiotherapy-induced telangiectasia.
    International journal of cancer, 2008, Dec-15, Volume: 123, Issue:12

    Topics: Breast Neoplasms; Female; Glutamic Acid; Glutathione Transferase; Humans; Logistic Models; Nitric Oxide Synthase Type III; Polymorphism, Single Nucleotide; Radiation Injuries; Radiotherapy; Risk Assessment; Risk Factors; Telangiectasis; Vasodilation

2008
An uncommon paraneoplastic Ri-positive opsoclonus-myoclonus-like syndrome and stiff-person syndrome with elevated glutamate/GABA ratio in the cerebrospinal fluid after breast cancer.
    Journal of neurology, 2010, Volume: 257, Issue:7

    Topics: Antigens, Neoplasm; Autoantibodies; Breast Neoplasms; Disease Progression; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Middle Aged; Nerve Tissue Proteins; Neuro-Oncological Ventral Antigen; Opsoclonus-Myoclonus Syndrome; RNA-Binding Proteins; Stiff-Person Syndrome

2010
Differential expression of glu-tubulin in relation to mammary gland disease.
    Virchows Archiv : an international journal of pathology, 2010, Volume: 457, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Breast Diseases; Breast Neoplasms; Female; Glutamic Acid; Humans; Middle Aged; Tubulin; Tyrosine

2010
Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.
    Nature, 2011, Aug-18, Volume: 476, Issue:7360

    Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genomics; Glutamic Acid; Humans; Ketoglutaric Acids; Melanoma; Mice; Neoplasm Transplantation; Phosphoglycerate Dehydrogenase; RNA Interference; Serine

2011
Cytosolic carboxypeptidase 1 is involved in processing α- and β-tubulin.
    The Journal of biological chemistry, 2012, Feb-24, Volume: 287, Issue:9

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Cytosol; Female; Glutamic Acid; GTP-Binding Proteins; HEK293 Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Nerve Degeneration; Peptide Synthases; Protein Structure, Tertiary; Purkinje Cells; Serine-Type D-Ala-D-Ala Carboxypeptidase; Swine; Tubulin

2012
Breast and lung cancer are associated with a decrease in blood cell amino acid content.
    The Journal of nutritional biochemistry, 2003, Volume: 14, Issue:3

    Topics: Adult; Aged; Amino Acids; Amino Acids, Essential; Asparagine; Blood Cells; Breast Neoplasms; Female; Glutamic Acid; Humans; Lung Neoplasms; Male; Middle Aged; Ornithine; Plasma; Proline; Valine

2003
Agonist-dependent and agonist-independent transactivations of the human constitutive androstane receptor are modulated by specific amino acid pairs.
    The Journal of biological chemistry, 2004, Aug-06, Volume: 279, Issue:32

    Topics: Amino Acid Sequence; Animals; Binding Sites; Breast Neoplasms; Constitutive Androstane Receptor; Cysteine; Dimerization; Drug Stability; Glutamic Acid; Humans; Isoleucine; Leucine; Lysine; Mice; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Receptors, Calcitriol; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Sequence Alignment; Signal Transduction; Structure-Activity Relationship; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured

2004
Potential role of a novel transcriptional coactivator PELP1 in histone H1 displacement in cancer cells.
    Cancer research, 2004, Sep-15, Volume: 64, Issue:18

    Topics: Bone Neoplasms; Breast Neoplasms; Cell Line, Tumor; Chromatin; Co-Repressor Proteins; Cytosol; Epitopes; Estradiol; Glutamic Acid; Histones; Humans; Nuclear Matrix; Osteosarcoma; Plasmids; Precipitin Tests; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Trans-Activators; Transcription Factors

2004
The HOPE-technique permits Northern blot and microarray analyses in paraffin-embedded tissues.
    Pathology, research and practice, 2004, Volume: 200, Issue:7-8

    Topics: Blotting, Northern; Breast Neoplasms; Female; Glutamic Acid; Glyceraldehyde-3-Phosphate Dehydrogenases; HEPES; HMGB1 Protein; Humans; Oligonucleotide Array Sequence Analysis; RNA; Solvents; Tissue Fixation

2004
Structure of the BRCT repeat domain of MDC1 and its specificity for the free COOH-terminal end of the gamma-H2AX histone tail.
    The Journal of biological chemistry, 2005, Sep-16, Volume: 280, Issue:37

    Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Breast Neoplasms; Calorimetry; Cell Cycle Proteins; Crystallography, X-Ray; DNA Damage; DNA-Binding Proteins; Escherichia coli; Glutamic Acid; Glutamine; Glutathione Transferase; Histones; Humans; Models, Molecular; Models, Statistical; Molecular Sequence Data; Nuclear Proteins; Peptides; Phosphates; Phosphopeptides; Phosphorylation; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Trans-Activators; Tyrosine

2005
Polymorphisms of ADPRT Val762Ala and XRCC1 Arg399Glu and risk of breast cancer in Chinese women: a case control analysis.
    Oncology reports, 2006, Volume: 15, Issue:1

    Topics: Adult; Alanine; Amino Acid Substitution; Arginine; Asian People; Breast Neoplasms; Case-Control Studies; China; DNA-Binding Proteins; Female; Genetic Predisposition to Disease; Glutamic Acid; Humans; Middle Aged; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Polymorphism, Genetic; Risk; Valine; X-ray Repair Cross Complementing Protein 1

2006
Lack of association between NOS3 Glu298Asp and breast cancer risk: a case-control study.
    Breast cancer research and treatment, 2006, Volume: 100, Issue:3

    Topics: Aspartic Acid; Breast Neoplasms; Case-Control Studies; Female; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Glutamic Acid; Humans; Nitric Oxide Synthase Type III; Odds Ratio; Polymorphism, Genetic; Risk Assessment; Risk Factors; Spain

2006
Estradiol stimulates the biosynthetic pathways of breast cancer cells: detection by metabolic flux analysis.
    Metabolic engineering, 2006, Volume: 8, Issue:6

    Topics: Algorithms; Amino Acids; Biosynthetic Pathways; Breast Neoplasms; Carbon Isotopes; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Estradiol; Female; Glucose; Glutamic Acid; Glutamine; Humans; Lactic Acid; Mitochondria; Models, Biological; Nuclear Magnetic Resonance, Biomolecular

2006
Wild-type class I beta-tubulin sensitizes Taxol-resistant breast adenocarcinoma cells harboring a beta-tubulin mutation.
    Cancer letters, 2007, Nov-18, Volume: 257, Issue:2

    Topics: Adenocarcinoma; Alkanes; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Carbamates; Cell Line, Tumor; Cell Survival; Dimerization; Docetaxel; Drug Resistance, Neoplasm; Epothilones; Fluorescent Antibody Technique, Indirect; Glutamic Acid; Glycine; Humans; Lactones; Models, Molecular; Mutation, Missense; Paclitaxel; Protein Structure, Quaternary; Pyrones; Taxoids; Transfection; Tubulin; Tubulin Modulators

2007
Identification of BRCA1 missense substitutions that confer partial functional activity: potential moderate risk variants?
    Breast cancer research : BCR, 2007, Volume: 9, Issue:6

    Topics: Alanine; Arginine; Biomarkers, Tumor; Breast Neoplasms; Centrosome; DNA, Complementary; Factor Analysis, Statistical; Female; Genes, BRCA1; Genetic Predisposition to Disease; Glutamic Acid; Glutamine; Glycine; Humans; Immunohistochemistry; Keratins; Mutation, Missense; Nucleic Acid Amplification Techniques; Plasmids; Polymorphism, Single Nucleotide; Predictive Value of Tests; Receptors, Estrogen; Risk Assessment; Risk Factors; Sequence Analysis, DNA; Valine

2007
Breast cancer-associated mutations in metalloprotease disintegrin ADAM12 interfere with the intracellular trafficking and processing of the protein.
    International journal of cancer, 2008, Jun-01, Volume: 122, Issue:11

    Topics: ADAM Proteins; ADAM12 Protein; Animals; Aspartic Acid; Biotinylation; Blotting, Western; Breast Neoplasms; Cell Movement; Female; Fluorescent Antibody Technique; Glutamic Acid; Glycine; Histidine; Humans; Immunoprecipitation; Leucine; Membrane Proteins; Mice; Mutation; Phenylalanine

2008
Mutational analysis of oncogenic AKT E17K mutation in common solid cancers and acute leukaemias.
    British journal of cancer, 2008, May-06, Volume: 98, Issue:9

    Topics: Acute Disease; Adenocarcinoma; Adult; Aged; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; DNA Mutational Analysis; Female; Glutamic Acid; Humans; Leukemia; Liver Neoplasms; Lung Neoplasms; Lysine; Male; Middle Aged; Mutation; Neoplasms; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Proteins c-akt; Stomach Neoplasms

2008
Improved tolerance of vincristine by glutamic acid. A preliminary report.
    Journal of neuro-oncology, 1984, Volume: 2, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Therapy, Combination; Female; Glutamates; Glutamic Acid; Humans; Nervous System Diseases; Vincristine

1984
Differential effect of glucose deprivation on MAPK activation in drug sensitive human breast carcinoma MCF-7 and multidrug resistant MCF-7/ADR cells.
    Molecular and cellular biochemistry, 1997, Volume: 170, Issue:1-2

    Topics: Breast Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Doxorubicin; Drug Resistance, Multiple; Enzyme Activation; Female; Glucose; Glutamic Acid; Glutamine; Humans; Kinetics; MAP Kinase Kinase Kinase 1; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; ras Proteins; Signal Transduction; Tumor Cells, Cultured

1997
Regulation of glutamine synthetase in human breast carcinoma cells and experimental tumors.
    Surgery, 1997, Volume: 122, Issue:2

    Topics: Animals; Breast Neoplasms; Cell Division; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Humans; Mice; Mice, Nude; Protein Biosynthesis; RNA, Messenger; Transcription, Genetic; Transplantation, Heterologous; Tumor Cells, Cultured

1997
Glucose deprivation-induced cytotoxicity and alterations in mitogen-activated protein kinase activation are mediated by oxidative stress in multidrug-resistant human breast carcinoma cells.
    The Journal of biological chemistry, 1998, Feb-27, Volume: 273, Issue:9

    Topics: Acetylcysteine; Breast Neoplasms; Carcinoma; Cell Death; Drug Resistance, Multiple; Enzyme Activation; Female; Glucose; Glutamic Acid; Glutamine; Glutathione; Glutathione Disulfide; Humans; Mitogen-Activated Protein Kinase 1; Oxidative Stress; Signal Transduction; Tumor Cells, Cultured

1998
Determinants of glutamine dependence and utilization by normal and tumor-derived breast cell lines.
    Journal of cellular physiology, 1998, Volume: 176, Issue:1

    Topics: Biological Transport; Breast Neoplasms; Carbon Dioxide; Cell Division; Culture Media; Cystine; Glutamic Acid; Glutamine; Glutathione; Humans; Kinetics; Sodium; Tumor Cells, Cultured

1998
A new BRCA1 germline mutation (E879X) in a Malaysian breast cancer patient of Chinese descent.
    Human mutation, 2000, Volume: 15, Issue:5

    Topics: Amino Acid Substitution; Asian People; BRCA1 Protein; Breast Neoplasms; Carcinoma, Ductal, Breast; China; Female; Germ-Line Mutation; Glutamic Acid; Humans; Malaysia; Middle Aged

2000
Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the A alpha subunit gene.
    Oncogene, 2001, Jan-04, Volume: 20, Issue:1

    Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Breast Neoplasms; Female; Glutamic Acid; Glycine; Humans; Lung Neoplasms; Melanoma; Molecular Sequence Data; Neoplasms; Peptide Fragments; Phosphoprotein Phosphatases; Point Mutation; Protein Binding; Protein Phosphatase 2; Protein Structure, Secondary; Tryptophan

2001
Identification by mass spectrometry of a new alpha-tubulin isotype expressed in human breast and lung carcinoma cell lines.
    Biochemistry, 2001, Feb-20, Volume: 40, Issue:7

    Topics: Amino Acid Sequence; Animals; Brain Chemistry; Breast Neoplasms; Cattle; Cyanogen Bromide; Glutamic Acid; Humans; Lung Neoplasms; Mass Spectrometry; Molecular Sequence Data; Peptide Fragments; Phylogeny; Protein Isoforms; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tubulin; Tumor Cells, Cultured

2001
Three new prodrugs for suicide gene therapy using carboxypeptidase G2 elicit bystander efficacy in two xenograft models.
    Cancer research, 2002, Mar-15, Volume: 62, Issue:6

    Topics: Animals; Antineoplastic Agents; beta-Galactosidase; Breast Neoplasms; Colorectal Neoplasms; Female; gamma-Glutamyl Hydrolase; Genetic Therapy; Glutamic Acid; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Prodrugs; Transfection; Xenograft Model Antitumor Assays

2002
Metabolic studies of estrogen- and tamoxifen-treated human breast cancer cells by nuclear magnetic resonance spectroscopy.
    Cancer research, 1989, Feb-01, Volume: 49, Issue:3

    Topics: Breast Neoplasms; Cell Line; Estradiol; Glucose; Glutamates; Glutamic Acid; Humans; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Phosphates; Phosphorylcholine; Tamoxifen

1989
Plasma glutamate--a prognostic marker of cancer and of other immunodeficiency syndromes?
    Scandinavian journal of clinical and laboratory investigation, 1989, Volume: 49, Issue:8

    Topics: Aged; Amino Acids; Breast Neoplasms; Colorectal Neoplasms; Female; Glutamates; Glutamic Acid; HIV Infections; Humans; Male; Middle Aged; Prognosis

1989