glutamic acid and Brain Neoplasms

glutamic acid has been researched along with Brain Neoplasms in 168 studies

Research

Studies (168)

TimeframeStudies, this research(%)All Research%
pre-19903 (1.79)18.7374
1990's20 (11.90)18.2507
2000's42 (25.00)29.6817
2010's79 (47.02)24.3611
2020's24 (14.29)2.80

Authors

AuthorsStudies
Akkulak, A; Dağdelen, DN; Diniz, G; Kahraman, DS; Oktay, E; Şenoğlu, M; Yalçın, A; Yalcin, GD1
Gunn, B; Keniry, M; Litif, C; Lopez, A; Schuenzel, E; Udawant, S1
Menard, F; Tabatabaee, M1
Chinnaiyan, P; Cho, K; Dunphy, MP; Frankfater, C; Gass, H; Graham, MS; Grkovski, M; Ippolito, JE; Jones, JK; Krebs, S; Luo, J; Mauguen, A; Nunez, E; Patti, GJ; Rubin, JB; Schaefer, J; Spitz, DR; Sponagel, J; Tinkum, KL; Tung, O; Zhang, S1
Feyissa, AM; Quiñones-Hinojosa, A; Rosenfeld, SS1
Conejos-Sánchez, I; Masiá, E; Melnyk, T; Vicent, MJ; Zagorodko, O1
Ashkan, K; Kumaria, A1
Jo, S; Kang, H; Kang, J; Kim, B; Kim, HY; Lee, H; Lee, JM; Lee, JS; Park, E; Park, J; Shin, E; Youn, B; Youn, H1
Galland, F; Gonçalves, CA; Leite, MC; Seady, M; Smaili, SS; Taday, J1
Campbell, SC; Chaunsali, L; Mills, WA; Muñoz-Ballester, C; Robel, S; Sontheimer, H; Yang, JH1
Erisnor, G; Khan, A; Lee, KC; Pei, Z; Wang, HY1
Gillespie, DL; Huang, LE; Jensen, RL; Tiburcio, PDB1
Bao, L; Chen, Y; DeBerardinis, RJ; Hatanpaa, KJ; Luo, W; Patel, T; Shi, X; Wang, Y; Zhang, B; Zhou, M1
Asklund, T; Bergenheim, AT; Bergström, P; Björn, E; Johansson, M; Tabatabaei, P1
Biffoni, M; Buccarelli, M; Ciocca, M; Cirrone, GAP; Dini, V; Grande, S; Guidoni, L; Luciani, AM; Pallini, R; Palma, A; Ricci-Vitiani, L; Rosi, A; Viti, V1
Batsios, G; Gillespie, AM; Lakhani, A; Molloy, AR; Najac, C; Pieper, RO; Radoul, M; Ronen, SM; Subramani, E; Viswanath, P1
D'Cruze, L; Ganesh, K; Pacharla, H; Padmavathy, KP; Pitani, R; Prathiba, D; Rayala, SK; Saravanan, R; Venkatraman, G; Venu, A; Vuttaradhi, VK1
Cseh, O; Luchman, HA; Pugh, TJ; Restall, IJ; Richards, LM; Weiss, S1
Chen, C; Hu, X; Moni, MA; Peng, S; Quinn, JMW; Rahman, MH; Rana, HK1
Abe, M; Hirose, Y; Inamasu, J; Kumon, M; Kuwahara, K; Murayama, K; Nakae, S; Ohba, S; Sasaki, H; Yamada, S1
Akkulak, A; Dagdelen, DN; Donmez Yalcin, G1
Hörnschemeyer, J; Kirschstein, T; Lange, F1
Banyas, E; Benbenishty, A; Blinder, P; David, S; Goldshmit, Y; Mayo, L; Perelroizen, R; Ruban, A; Shalom, M; Yakovchuk, A1
Belcaid, Z; Brem, H; Choi, J; Ehresman, J; Huq, S; Jackson, C; Jackson, CM; Kim, T; Kim, YH; Lim, M; Mathios, D; Medikonda, R; Pant, A; Patel, K; Pennington, Z; Routkevitch, D; Saleh, L; Shah, PP; Srivastava, S; Tong, L; Tyler, B; Xia, Y1
Catalano, M; Civiero, L; D'Agnano, I; Familiari, G; Familiari, P; Iovino, L; Limatola, C; Monaco, L; Raspa, M; Relucenti, M; Scavizzi, F; Serpe, C1
Buchfelder, M; Chen, D; Eyupoglu, IY; Fan, Z; Rauh, M; Savaskan, N1
Bachoo, RM; Baskin, DS; Ijare, OB; Maher, EA; Malloy, CR; Marin-Valencia, I; Mashimo, T; Mickey, BE; Pichumani, K; Vemireddy, V1
Cudalbu, C; Gruetter, R; Hamou, MF; Hegi, ME; Lai, M; Lanz, B; Poitry-Yamate, C; Vassallo, I1
Camelo-Piragua, S; Chinnaiyan, A; Koschmann, C; Leung, D; McFadden, K; Mody, R; Pratt, D; Venneti, S1
Botman, D; de Bitter, T; Heerschap, A; Hendriks, W; Huynen, MA; Khurshed, M; Kusters, B; Leenders, WPJ; Lenting, K; Molenaar, RJ; Peeters, TH; Span, PN; Ter Laan, M; van den Heuvel, CNAM; van Ewijk, A; van Lith, SAM; van Noorden, CJF; Verrijp, K1
Cerdán, S; García-Martín, ML; Lopez-Larrubia, P; Mucci, A; Righi, V; Schenetti, L; Tugnoli, V1
Akashi, K; Baba, E; Hirata, Y; Kamenori, S; Mitsuishi, Y; Nagano, O; Okazaki, S; Sampetrean, O; Saya, H; Shintani, S; Suina, K; Takahashi, F; Takahashi, K; Tsuchihashi, K; Yamasaki, J1
Bergner, C; Hörnschemeyer, J; Kirschstein, T; Köhling, R; Krause, BJ; Lange, F; Linnebacher, M; Mullins, CS; Porath, K; Weßlau, K1
Davis, KA; Desmond, P; Drummond, K; Glarin, R; Hariharan, H; Kwan, P; Moffat, BA; Morokoff, A; Nanga, RPR; Neal, A; O'Brien, TJ; Reddy, R; Shinohara, RT; Stein, JM1
Chappé, C; Colin, C; Figarella-Branger, D; Fina, F; Forest, F; Lena, G; Loundou, A; Mercurio, S; Nanni-Metellus, I; Padovani, L; Scavarda, D1
Batchelor, TT; Borger, DR; Chi, AS; Dias-Santagata, D; Ellisen, LW; Iafrate, AJ; Louis, DN; Yang, D1
Bachoo, R; Choi, C; Deberardinis, R; Dimitrov, I; Ganji, S; Hulsey, K; Kovacs, Z; Madan, A; Maher, E; Malloy, C; Mendelsohn, D; Mickey, B; Pichumani, K; Zhang, S1
Amos, A; Bost, J; Maroon, J; Zuccoli, G1
Blecic, S; De Witte, O; Lefranc, F; Rynkowski, M1
Robert, SM; Sontheimer, H1
D'Alonzo, D; Glatz, K1
Hirato, J; Ikota, H; Kurihara, H; Nagaishi, M; Nakazato, Y; Nobusawa, S; Ogawa, A; Okura, N; Yokoo, H1
Bjorksten, A; Desmond, PM; Drummond, KJ; Kaye, AH; Liubinas, SV; Moffat, BA; Morokoff, AP; O'Brien, TJ1
Drummond, KJ; Kaye, AH; Liubinas, SV; Moffat, BM; Morokoff, AP; O'Brien, TJ1
Bjerkvig, R; Leenders, WP; Molenaar, R; Navis, AC; Niclou, SP; Tops, B; van Lith, SA; van Noorden, CJ; Verrijp, K; Wesseling, P1
Cai, L; Chaumeil, MM; Eriksson, P; Larson, PE; Lupo, JM; Nelson, SJ; Phillips, JJ; Pieper, RO; Robinson, AE; Ronen, SM; Vigneron, DB; Woods, SM1
Hayashi, Y; Miyashita, K; Nakada, M; Nobusawa, S; Sabit, H; Suzuki, SO; Tanaka, S1
Deneka-Hannemann, S; Jarosz, B; Rzeski, W; Stoma, F; Trojanowski, T; Turski, WA; Walczak, K; Zgrajka, W1
Arvanitis, TN; English, M; Gill, SK; MacPherson, L; Peet, AC; Wilson, M1
LeBoeuf, NR; Lee, EQ; Ruland, S; Santagata, S; Wen, PY1
Chen, R; Daemen, A; Deng, Y; Forrest, WF; Friedman, LS; Hatzivassiliou, G; Hedehus, M; Kharbanda, S; Kwong, M; Nishimura, MC; Peale, F; Phillips, HS1
Chen, J; Gao, H; He, Q; Jiang, X; Qian, J; Ruan, S; Shen, S; Yang, W; Zhu, J1
McGovern, RA; McKhann, GM; Nelp, TB1
Amiridis, S; Ching, J; Kaye, AH; Morokoff, AP; O'Brien, TJ; Stylli, SS1
Bachoo, RM; Barnett, S; DeBerardinis, RJ; Foong, C; Hatanpaa, KJ; Huang, Z; Kovacs, Z; Maher, EA; Mashimo, T; Mickey, BE; Nannepaga, S; Piccirillo, SG; Pichumani, K; Singh, DK; Sirasanagandla, S; Tu, BP; Vemireddy, V1
Kang, DZ; Lin, RY; Wang, XF; Yao, PS; Ye, ZC1
Ejima, Y; Gini, B; Hosoda, K; Imahori, T; Irino, Y; Kohmura, E; Kyotani, K; Masui, K; Mischel, PS; Mizowaki, T; Nagashima, H; Sasaki, R; Sasayama, T; Satoh, N; Takata, K; Tanaka, K; Yang, H1
Amiridis, S; Bjorksten, AR; Ching, J; Kaye, AH; Kountouri, N; Luwor, RB; Morokoff, AP; O'Brien, TJ; Paradiso, L; Stylli, SS; Zheng, T1
Choi, J; Régnier-Vigouroux, A; Savaskan, NE; Stradmann-Bellinghausen, B; Yakubov, E1
Wang, K; Zhang, K; Zhou, F; Zhu, L; Zhu, X1
Hansen, H; Hashizume, Y; Loiacono, KA; Rojas, C; Sahni, V; Sattler, R; Slusher, BS; Tendyke, K; Thomas, AG1
Boillée, S; Hewett, S; Knackstedt, L; Lewerenz, J; Massie, A1
Broggini, T; Buchfelder, M; Eyüpoglu, IY; Fan, Z; Savaskan, NE1
Cheng, M; Eberhart, CG; Fan, X; Glunde, K; Kahlert, UD; Koch, K; Maciaczyk, J; Marchionni, L; Raabe, EH1
Dembitskaya, Y; Kazantsev, V; Medyanik, I; Mishchenko, M; Tyurikova, O; Vedunova, M; Yashin, K1
Ahmed, SU; Barnett, SC; Bjerkvig, R; Chalmers, AJ; Fack, F; Gottlieb, E; Hock, AK; Keunen, O; Lindsay, SL; Lund-Johansen, M; Miletic, H; Mørkve, SH; Niclou, SP; Oudin, A; Ruppin, E; Sakariassen, PØ; Tardito, S; Wagner, A; Weinstock, A; Zheng, L1
Chamberlain, MC1
Bacher-Stier, C; Berndt, M; Bullich, S; Chin, FT; Dinkelborg, LM; Fels, LM; Friebe, M; Gambhir, SS; Gekeler, V; Hoehne, A; Iagaru, AH; Keu, KV; Koglin, N; Kumar, M; Mittra, ES; Moon, DH; Mosci, C; Mueller, A; Schmitt-Willich, H; Stephens, AW1
Huberfeld, G; Vecht, CJ1
Abe, S; Akashi, K; Akiyama, T; Baba, E; Furnari, FB; Ishikawa, M; Iwasaki, Y; Masuko, T; Morikawa, T; Nagane, M; Nagano, O; Ohmura, M; Okazaki, S; Onishi, N; Sampetrean, O; Saya, H; Seishima, R; Shimizu, M; Suematsu, M; Takao, A; Tsuchihashi, K; Wakimoto, H; Yoshikawa, M1
Hosoda, K; Irino, Y; Itoh, T; Kohmura, E; Kyotani, K; Mizukawa, K; Mukasa, A; Nagashima, H; Sakata, J; Sasaki, R; Sasayama, T; Sato, N; Takeuchi, Y; Tanaka, K; Yamamoto, Y1
Gottschalk, M; Grand, S; Lamalle, L; Le Bas, JF; Segebarth, C; Troprès, I1
Bulik, M; Jancalek, R; Kazda, T; Lakomy, R; Pospisil, P; Slampa, P; Smrcka, M1
D'Orazio, F; Di Cesare, E; Patriarca, L; Splendiani, A1
Carro, MS; Heiland, DH; Lange, T; Mader, I; Pfeifer, D; Schlosser, P; Schwarzwald, R; Urbach, H; Vasilikos, I; Weyerbrock, A1
Gilberto González, R; Ratai, EM1
Ceccanti, M; Chassidim, Y; Colonnese, C; D'Elia, A; Fassler, M; Friedman, A; Inghilleri, M; Nucciarelli, V; Onesti, E; Pell, GS; Prager, O; Raccah, R; Roth, Y; Salvati, M; Santoro, A; Shahar, H; Vazana, U; Veksler, R; Zangen, A1
MacKenzie, G; Maguire, J; Moss, SJ; O'Toole, KK1
Bastian, BC; Bollen, AW; Chen, K; Gong, H; Jin, LW; Joseph, NM; Nicolaides, T; Perry, A; Phillips, JJ; Shieh, JT; Solomon, DA; van Ziffle, J1
Bergenheim, AT; Bergström, P; Brännström, T; Siesjö, P; Tabatabaei, P; Visse, E1
Maus, A; Peters, GJ1
Albrecht, J; Szeliga, M1
Ding, MP; Ding, Y; Guo, Y; Shen, CH; Tang, YL; Wang, S; Zhang, YX; Zheng, Y; Zhu, JM1
Aizenstein, O; Artzi, M; Ben Bashat, D; Bokstein, F; Liberman, G; Vaisman, N; Vitinshtein, F1
Koster, J; Lasky, JL; Lin, HJ; Panosyan, EH1
Bergenheim, AT; Bergström, P; Henriksson, R; Tabatabaei, P1
Simpkins, JW; Yi, KD1
Bjerkvig, R; Enger, PØ; Hajek, M; Jirak, D; Sykova, E; Thorsen, F; van der Kogel, A; Wang, J1
Bergenheim, AT; Lindvall, P; Roslin, M1
Fan, GG; Guo, QY; Sun, HZ; Wang, GL1
Aronica, E; Boer, K; Gorter, JA; Jansen, F; Nellist, M; Spliet, WG; Timmermans, W; Troost, D1
Avdievich, NI; Baehring, JM; Hetherington, HP; Pan, JW; Spencer, DD1
Hou, BL; Hu, J1
Eyüpoglu, IY; Hahnen, E; Savaskan, NE1
Aronica, E; Bosma, I; Broekhuizen, AJ; Cloos, J; Heimans, JJ; Kaspers, GJ; Postma, TJ; Tannous, BA; van der Valk, P; van Vuurden, DG; Würdinger, T; Yazdani, M1
Darra, E; Ebner, FH; Mariotto, S; Shoji, K; Suzuki, H1
Eyüpoglu, IY; Hahnen, E; Hauke, J; Savaskan, NE; Seufert, S; Tränkle, C1
Ackermann, H; Blasel, S; Franz, K; Hattingen, E; Weidauer, S; Zanella, F1
Liu, SC; Wang, YY; Yang, Z; Zhang, T1
de Groot, J; Sontheimer, H1
Eloqayli, H; Haukvik, A; Melø, TM; Sonnewald, U1
Choi, JK; Das, SK; Dash, R; Emdad, L; Fisher, PB; Howlett, EL; Jeon, HY; Kang, DC; Kegelman, TP; Kim, K; Kim, SH; Lee, SG; Sarkar, D; Su, ZZ; Yoo, BK1
Buckingham, SC; Campbell, SL; Haas, BR; Montana, V; Ogunrinu, T; Robel, S; Sontheimer, H1
Simon, M; von Lehe, M1
Berghoff, AS; Birner, P; Capper, D; Habel, A; Hackl, M; Ilhan, A; Magerle, M; Meyer, J; Petzelbauer, P; Pichler, J; Preusser, M; Pusch, S; von Deimling, A; Wöhrer, A1
Sontheimer, H3
Cai, K; Detre, JA; Greenberg, JH; Hariharan, H; Haris, M; Kogan, F; Reddy, R; Singh, A1
Galeffi, F; Turner, DA1
Bachoo, RM; Cho, SK; Choi, C; Deberardinis, RJ; Good, LB; Hatanpaa, KJ; Jindal, A; Kapur, P; Maher, EA; Malloy, CR; Marin-Valencia, I; Mashimo, T; Mickey, B; Pascual, JM; Raisanen, J; Rakheja, D; Sun, X; Takahashi, M; Togao, O; Vemireddy, V1
Berkutzki, T; Cooper, I; Mohar, B; Ruban, A; Teichberg, VI1
Bachoo, RM; Baek, H; Cai, L; Cho, S; Deberardinis, RJ; Good, L; Hatanpaa, KJ; Maddie, M; Maher, EA; Malloy, CR; Marin-Valencia, I; Mashimo, T; Matés, JM; Mickey, BE; Pascual, JM; Rajagopalan, KN; Tu, BP; Vemireddy, V; Yang, C; Yang, XL; Zhao, Z1
Buckingham, SC; Campbell, SL; Sontheimer, H1
Bode, J; Caballero, B; Gaitner, M; Gavish, M; Kietz, S; Kugler, W; Lakomek, M; Peʼer, Y; Veenman, L; Zeno, S1
Barzó, P; Komlósi, G; Molnár, G; Oláh, S; Rózsa, M; Tamás, G1
Celio, MR; D'Orlando, C; Schwaller, B1
Rothstein, JD1
Acebes, JJ; Aguilera, C; Alonso, J; Arús, C; Gili, J; Majós, C; Serrallonga, M1
Bernsen, H; Boerman, R; Heerschap, A; Rijpkema, M; Schuuring, J; van der Graaf, M; van der Kogel, A; van der Meulen, Y1
Dezortová, M; Hájek, M; Liscák, R; Vladyka, V; Vymazal, J1
Buydens, LM; Heerschap, A; Melssen, WJ; Postma, GJ; Simonetti, AW; van der Graaf, M1
Blanco, I; Dot, J; Lluch, M; Rodríguez-Alvarez, J1
Sutherland, ML; Zhou, J1
Brennan, L; Hewage, C; Malthouse, JP; McBean, GJ1
McKnight, TR1
Bos, IW; de Graan, PN; Notenboom, RG; van der Hel, WS; van Rijen, PC; van Veelen, CW1
Beretta, S; Carrì, MT; Ceresa, C; Ferrarese, C; Ferri, A; Mattavelli, L; Sala, G; Tremolizzo, L; Zoia, C1
Imbesi, SG; Niku, S; Panchal, NJ1
Grand, S; Hoffmann, D; Le Bas, JF; Tropres, I; Ziegler, A1
Bergenheim, AT; Henriksson, R; Ronquist, G; Roslin, M; Ungerstedt, U; Waldenström, A1
Haacke, EM; Hu, J; Jiang, Q; Xuan, Y; Yang, S; Yang, Y1
Cianfoni, A; Imbesi, SG; Niku, S1
Allritz, C; Engele, J; Rein, T; Zschocke, J1
Igarashi, H; Kimura, T; Kwee, IL; Nakada, T; Ohkubo, M1
Chung, WJ; Lyons, SA; Ogunrinu, T; Sontheimer, H; Weaver, AK1
Hu, J; Kou, Z; Yang, S; Yang, Y1
Akhyani, N; Fotheringham, J; Jacobson, S; Williams, EL1
Cheng, FC; Cheng, H; Chou, SC; Fu, YS; Fu, YY; Hsu, SY; Kao, LS; Lin, YY; Shih, YH; Tsai, TH; Wang, JY1
Kitano, H; Shinohara, H; Zakir Hossain, SM1
Allen, JC; Benua, RS; Gelbard, AS; Laughlin, JS; Reiman, RE; Vomero, JJ1
Bansinath, M; Garg, UC; Turndorf, H1
Bredesen, DE; Kane, DJ; Zhong, LT1
Bonner, K; Gennarelli, L; Rorke, LB; Sutton, LN; Wang, Z; Wehrli, SL; Zimmerman, R1
Els, T; Gyngell, ML; Hoehn-Berlage, M; Hossmann, KA1
Cornell-Bell, AH; Lee, SH; Magge, S; Sontheimer, H; Spencer, DD1
Bhakoo, KK; Florian, CL; Noble, M; Preece, NE; Williams, SR1
Kato, S; Mawatari, K; Sugitani, K; Takadera, T; Yasui, Y1
Haghighat, N; McCandless, DW1
Albasanz, JL; Martín, M; Ros, M1
Debinski, W; Gibo, DM; Kealiher, A; Obiri, NI; Puri, RK1
Baunach, S; Gerlach, M; Lan, J; Meixensberger, J; Roosen, K1
DelaBarre, L; Garwood, M; Gruetter, R; High, WB; Merkle, H; Mescher, M; Terpstra, M1
Li, SJ; Prost, R; Rand, SD1
Bouzier, AK; Canioni, P; Merle, M; Quesson, B; Valeins, H1
Blomenröhr, M; de Graan, PN; de Wit, M; Dijstelbloem, H; Gispen, WH; Hoogland, G; Spierenburg, HA; van Huffelen, AC; van Rijen, PC; van Veelen, CW1
Ha, JH; Huh, K; Jung, MW; Kang, YS; Kim, JA; Lee, DU; Lee, SH; Lee, YS; Yong, CS1
Rothstein, JD; Sontheimer, H; Ye, ZC1
Behrens, PF; Draeger, J; Hennig, J; Langemann, H; Strohschein, R1
Décorps, M; Rémy, C; von Kienlin , M; Ziegler, A1
Brem, H; Rothstein, JD1
Arcuino, G; Gao, Q; Lin, JH; Nedergaard, M; Takano, T; Yang, J1
Adamek, D; Danilewicz, B; Jeleńska-Szyguła, I; Korzeniowska, A; Lopatka, P; Morga, R1
Baethmann, A; Kempski, O; Schneider, GH; Staub, F; Weigt, H1
Allard, M; Biran, M; Caille, JM; Canioni, P; Kien, P; Labouesse, J; Merle, M; Pianet, I; Portais, JC; Raffard, G1
Gotoh, F; Shinohara, T; Tomita, M1
Bartel, R; Bigner, DD; Campbell, GL; Freidman, HS1

Reviews

24 review(s) available for glutamic acid and Brain Neoplasms

ArticleYear
Glutamate Signaling and Filopodiagenesis of Astrocytoma Cells in Brain Cancers: Survey and Questions.
    Cells, 2022, 08-26, Volume: 11, Issue:17

    Topics: Astrocytes; Astrocytoma; Brain Neoplasms; Glutamic Acid; Humans; Signal Transduction

2022
Altered glutamatergic and inflammatory pathways promote glioblastoma growth, invasion, and seizures: An overview.
    Journal of the neurological sciences, 2022, 12-15, Volume: 443

    Topics: Brain Neoplasms; Glioblastoma; Glioma; Glutamic Acid; Humans; Seizures; Tumor Microenvironment

2022
Pathway analysis of glutamate-mediated, calcium-related signaling in glioma progression.
    Biochemical pharmacology, 2020, Volume: 176

    Topics: Animals; Brain Neoplasms; Calcium; Disease Progression; Glioblastoma; Glutamic Acid; Humans; Neurons; Nitric Oxide; Signal Transduction

2020
Glutamatergic Mechanisms in Glioblastoma and Tumor-Associated Epilepsy.
    Cells, 2021, 05-17, Volume: 10, Issue:5

    Topics: Animals; Anticonvulsants; Antineoplastic Agents; Brain; Brain Neoplasms; Brain Waves; Disease Progression; Epilepsy; Excitatory Amino Acid Antagonists; Glioblastoma; Glutamic Acid; Humans; Receptors, Ionotropic Glutamate; Receptors, Metabotropic Glutamate; Signal Transduction

2021
Restricted calorie ketogenic diet for the treatment of glioblastoma multiforme.
    Journal of child neurology, 2013, Volume: 28, Issue:8

    Topics: Animals; Brain Neoplasms; Caloric Restriction; Combined Modality Therapy; Diet, Ketogenic; Glioblastoma; Glucose; Glutamic Acid; Humans; United States

2013
[Glutamate and malignant gliomas, from epilepsia to biological aggressiveness: therapeutic implications].
    Bulletin du cancer, 2013, Volume: 100, Issue:9

    Topics: Benzodiazepines; Brain Neoplasms; Cell Death; Cell Movement; Cell Proliferation; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glioma; Glutamic Acid; Humans; Memantine; Neoplasm Invasiveness; Neuroglia; Neurons; Receptors, AMPA; Receptors, Glutamate; Seizures; Sulfasalazine

2013
Glutamate transporters in the biology of malignant gliomas.
    Cellular and molecular life sciences : CMLS, 2014, Volume: 71, Issue:10

    Topics: Amino Acid Transport System X-AG; Brain Neoplasms; Glioma; Glutamic Acid; Glutathione; Humans; Receptors, Glutamate

2014
Tumour associated epilepsy and glutamate excitotoxicity in patients with gliomas.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:6

    Topics: Animals; Brain Neoplasms; Epilepsy; Glioma; Glutamic Acid; Humans; Quality of Life; Synaptic Transmission

2014
Glutamate as chemotactic fuel for diffuse glioma cells: are they glutamate suckers?
    Biochimica et biophysica acta, 2014, Volume: 1846, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Transformation, Neoplastic; Chemotaxis; Enzyme Inhibitors; Glioma; Glutamic Acid; Glutamine; Humans; Isocitrate Dehydrogenase

2014
A novel treatment strategy for glioblastoma multiforme and glioma associated seizures: increasing glutamate uptake with PPARγ agonists.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2015, Volume: 22, Issue:1

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Excitatory Amino Acid Transporter 2; Glioblastoma; Glutamic Acid; Humans; PPAR gamma; Seizures

2015
Main path and byways: non-vesicular glutamate release by system xc(-) as an important modifier of glutamatergic neurotransmission.
    Journal of neurochemistry, 2015, Volume: 135, Issue:6

    Topics: Animals; Brain; Brain Neoplasms; Glioblastoma; Glutamic Acid; Humans; Oxidative Stress; Synaptic Transmission

2015
Perspectives in Intraoperative Diagnostics of Human Gliomas.
    Computational and mathematical methods in medicine, 2015, Volume: 2015

    Topics: Brain Neoplasms; Cell Movement; Computational Biology; Glioma; Glutamic Acid; Humans; Image-Guided Biopsy; Intraoperative Period; Magnetic Resonance Imaging; Optical Imaging; Surgery, Computer-Assisted; Ultrasonography

2015
Seizures and gliomas--towards a single therapeutic approach.
    Nature reviews. Neurology, 2016, Volume: 12, Issue:4

    Topics: Animals; Anticonvulsants; Brain Neoplasms; GABAergic Neurons; Glioma; Glutamic Acid; Humans; Seizures; Signal Transduction; TOR Serine-Threonine Kinases

2016
Vanishing pineal mass in a young patient without therapy: Case report and review of the literature.
    The neuroradiology journal, 2016, Volume: 29, Issue:5

    Topics: Adolescent; Aspartic Acid; Brain Neoplasms; Choline; Electroencephalography; Female; Glutamic Acid; Glutamine; Headache; Humans; Hydrocephalus; Magnetic Resonance Imaging; Pineal Gland; Pinealoma; Recovery of Function; Tomography, X-Ray Computed

2016
Clinical magnetic resonance spectroscopy of the central nervous system.
    Handbook of clinical neurology, 2016, Volume: 135

    Topics: Aspartic Acid; Brain Chemistry; Brain Neoplasms; Central Nervous System; Choline; Creatine; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy

2016
Glutamate and α-ketoglutarate: key players in glioma metabolism.
    Amino acids, 2017, Volume: 49, Issue:1

    Topics: Antimetabolites, Antineoplastic; Brain Neoplasms; Citric Acid Cycle; Gene Expression; Glioblastoma; Glutamic Acid; Humans; Isocitrate Dehydrogenase; Ketoglutaric Acids; Mutation; Neoplasm Grading; Reactive Oxygen Species

2017
[Progress in the study of the chemical synapse in glioma-associated epileptogenesis].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2008, Aug-18, Volume: 40, Issue:4

    Topics: Brain Neoplasms; Epilepsy; Glioma; Glutamic Acid; Humans; Neurotransmitter Agents; Neurotransmitter Transport Proteins; Synapses

2008
Glutamate and the biology of gliomas.
    Glia, 2011, Volume: 59, Issue:8

    Topics: Animals; Benzodiazepines; Brain; Brain Neoplasms; Glioma; Glutamic Acid; Humans; Models, Biological; Receptors, AMPA; Signal Transduction

2011
Exploiting metabolic differences in glioma therapy.
    Current drug discovery technologies, 2012, Volume: 9, Issue:4

    Topics: Brain Neoplasms; Glioma; Glutamic Acid; Glutamine; Humans; Hypoxia-Inducible Factor 1; NAD; NADP; Signal Transduction

2012
Ion channels and amino acid transporters support the growth and invasion of primary brain tumors.
    Molecular neurobiology, 2004, Volume: 29, Issue:1

    Topics: Amino Acid Transport Systems; Animals; Brain Neoplasms; Cell Division; Glioma; Glutamic Acid; Humans; Ion Channels; Neoplasm Invasiveness

2004
Proton magnetic resonance spectroscopic evaluation of brain tumor metabolism.
    Seminars in oncology, 2004, Volume: 31, Issue:5

    Topics: Alanine; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Lipid Metabolism; Magnetic Resonance Spectroscopy; Phosphocreatine

2004
A role for glutamate in growth and invasion of primary brain tumors.
    Journal of neurochemistry, 2008, Volume: 105, Issue:2

    Topics: Amino Acid Transport System X-AG; Animals; Antineoplastic Agents; Brain Neoplasms; Cystine; Glioma; Glutamic Acid; Humans; Neoplasm Invasiveness

2008
Proton MR spectroscopy of the brain.
    Neuroimaging clinics of North America, 1999, Volume: 9, Issue:2

    Topics: Brain; Brain Abscess; Brain Diseases; Brain Neoplasms; Carbon Isotopes; Cerebral Infarction; Demyelinating Diseases; Diagnosis, Differential; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Membrane Lipids; Multiple Sclerosis; Neurotransmitter Agents; Phosphorus Isotopes; Protons; United States; United States Food and Drug Administration

1999
Swelling of C6 glioma cells and astrocytes from glutamate, high K+ concentrations or acidosis.
    Progress in brain research, 1992, Volume: 94

    Topics: Acidosis, Lactic; Animals; Astrocytes; Brain Neoplasms; Cell Hypoxia; Cell Size; Glioma; Glutamates; Glutamic Acid; Iodoacetates; Iodoacetic Acid; Ouabain; Potassium; Rats; Sodium-Potassium-Exchanging ATPase; Tumor Cells, Cultured

1992

Trials

2 trial(s) available for glutamic acid and Brain Neoplasms

ArticleYear
Characterization of oligodendrogliomas using short echo time 1H MR spectroscopic imaging.
    NMR in biomedicine, 2003, Volume: 16, Issue:1

    Topics: Adult; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Dipeptides; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Oligodendroglioma; Reproducibility of Results; Sensitivity and Specificity

2003
Metabolic manipulation of glioblastoma in vivo by retrograde microdialysis of L-2, 4 diaminobutyric acid (DAB).
    Journal of neuro-oncology, 2006, Volume: 80, Issue:3

    Topics: Aged; Aminobutyrates; Antimetabolites, Antineoplastic; Brain Neoplasms; Catheters, Indwelling; Dose-Response Relationship, Drug; Female; Glioblastoma; Glutamic Acid; Glycerol; Humans; Infusions, Intralesional; Male; Microdialysis; Middle Aged; Monitoring, Ambulatory; Stereotaxic Techniques; Taurine; Treatment Outcome

2006

Other Studies

142 other study(ies) available for glutamic acid and Brain Neoplasms

ArticleYear
The expression of glutamate metabolism modulators in the intracranial tumors and glioblastoma cell line.
    Molecular biology reports, 2022, Volume: 49, Issue:2

    Topics: Adolescent; Adult; Aged; Astrocytes; Brain Neoplasms; Cell Line; Child; Child, Preschool; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Glioblastoma; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamic Acid; Humans; Male; Middle Aged; Mitochondrial Proteins; Neuroglia; Retrospective Studies; Sirtuins

2022
PI3K Pathway Inhibition with NVP-BEZ235 Hinders Glycolytic Metabolism in Glioblastoma Multiforme Cells.
    Cells, 2021, 11-07, Volume: 10, Issue:11

    Topics: Brain Neoplasms; Cell Line, Tumor; Forkhead Box Protein O1; Gene Expression Regulation, Neoplastic; Gene Ontology; Glioblastoma; Glucose; Glutamic Acid; Glycolysis; Humans; Imidazoles; Kaplan-Meier Estimate; Lactic Acid; NAD; Phosphatidylinositol 3-Kinases; Prognosis; Protein Kinase Inhibitors; Quinolines; Signal Transduction

2021
Sex differences in brain tumor glutamine metabolism reveal sex-specific vulnerabilities to treatment.
    Med (New York, N.Y.), 2022, 11-11, Volume: 3, Issue:11

    Topics: Animals; Brain Neoplasms; Citric Acid Cycle; Female; Glioma; Glutamic Acid; Glutamine; Humans; Male; Mice; Pyruvate Carboxylase; Sex Characteristics

2022
Rational design of poly-L-glutamic acid-palbociclib conjugates for pediatric glioma treatment.
    Journal of controlled release : official journal of the Controlled Release Society, 2023, Volume: 355

    Topics: Brain Neoplasms; Child; Diffuse Intrinsic Pontine Glioma; Glioma; Glutamic Acid; Humans

2023
Novel therapeutic strategies in glioma targeting glutamatergic neurotransmission.
    Brain research, 2023, 11-01, Volume: 1818

    Topics: Anticonvulsants; Brain Neoplasms; Glioblastoma; Glioma; Glutamic Acid; Humans; Synaptic Transmission

2023
Mitochondrial glutamate transporter SLC25A22 uni-directionally export glutamate for metabolic rewiring in radioresistant glioblastoma.
    International journal of biological macromolecules, 2023, Dec-31, Volume: 253, Issue:Pt 8

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glutamic Acid; Humans; Mitochondria; Mitochondrial Membrane Transport Proteins; Proline; Radiation Tolerance

2023
Astrocyte culture models: Molecular and function characterization of primary culture, immortalized astrocytes and C6 glioma cells.
    Neurochemistry international, 2019, Volume: 131

    Topics: Animals; Astrocytes; Brain Neoplasms; Cell Communication; Cell Line; Cell Proliferation; Glial Fibrillary Acidic Protein; Glioma; Glucose; Glutamic Acid; Glutathione; Immunohistochemistry; Male; Primary Cell Culture; Rats; Rats, Wistar; S100 Calcium Binding Protein beta Subunit

2019
Potassium and glutamate transport is impaired in scar-forming tumor-associated astrocytes.
    Neurochemistry international, 2020, Volume: 133

    Topics: Animals; Astrocytes; Biological Transport; Brain Neoplasms; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glioma; Glutamic Acid; Mice; Neuroglia; Neurons; Potassium

2020
Extracellular glutamate and IDH1
    Journal of neuro-oncology, 2020, Volume: 146, Issue:3

    Topics: Animals; Benzeneacetamides; Brain Neoplasms; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Glioma; Glutamate Dehydrogenase; Glutamic Acid; Humans; Imidazoles; Isocitrate Dehydrogenase; Male; Mice; Oxidation-Reduction; Tumor Cells, Cultured

2020
Regulation of branched-chain amino acid metabolism by hypoxia-inducible factor in glioblastoma.
    Cellular and molecular life sciences : CMLS, 2021, Volume: 78, Issue:1

    Topics: Amino Acids, Branched-Chain; Basic Helix-Loop-Helix Transcription Factors; Brain Neoplasms; Cell Hypoxia; Cell Proliferation; Cells, Cultured; CRISPR-Cas Systems; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Glioblastoma; Glutamic Acid; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Large Neutral Amino Acid-Transporter 1; Protein Binding; Transaminases

2021
Intratumoral retrograde microdialysis treatment of high-grade glioma with cisplatin.
    Acta neurochirurgica, 2020, Volume: 162, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain; Brain Neoplasms; Cisplatin; Female; Glioma; Glucose; Glutamic Acid; Glycerol; Humans; Male; Microdialysis; Middle Aged; Neoplasm Recurrence, Local; Quality of Life; Treatment Outcome

2020
Different Mechanisms Underlie the Metabolic Response of GBM Stem-Like Cells to Ionizing Radiation: Biological and MRS Studies on Effects of Photons and Carbon Ions.
    International journal of molecular sciences, 2020, Jul-21, Volume: 21, Issue:14

    Topics: Brain Neoplasms; Cell Line, Tumor; G2 Phase Cell Cycle Checkpoints; gamma-Aminobutyric Acid; Glioblastoma; Glucose; Glutamic Acid; Humans; Ions; Lactic Acid; Magnetic Resonance Spectroscopy; Neoplastic Stem Cells; Phosphocreatine; Photons; Radiation, Ionizing

2020
MR-detectable metabolic biomarkers of response to mutant IDH inhibition in low-grade glioma.
    Theranostics, 2020, Volume: 10, Issue:19

    Topics: Antineoplastic Agents; Biomarkers, Tumor; Brain Neoplasms; Carbon-13 Magnetic Resonance Spectroscopy; Cell Line, Tumor; Diamines; Glioma; Glutamic Acid; Glutarates; Glycine; Humans; Isocitrate Dehydrogenase; Mutation; Proton Magnetic Resonance Spectroscopy; Pyridines

2020
Clinical Evaluation of Proline, Glutamic acid, and Leucine-Rich Protein 1 Expression in Astrocytomas and Correlations with the Proliferation Marker Ki-67.
    Journal of molecular neuroscience : MN, 2021, Volume: 71, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Astrocytoma; Brain Neoplasms; Co-Repressor Proteins; Female; Glutamic Acid; Humans; Ki-67 Antigen; Male; Middle Aged; Neoplasm Grading; Proline; Transcription Factors

2021
Brain Tumor Stem Cell Dependence on Glutaminase Reveals a Metabolic Vulnerability through the Amino Acid Deprivation Response Pathway.
    Cancer research, 2020, 12-15, Volume: 80, Issue:24

    Topics: Amino Acids; Astrocytes; Benzeneacetamides; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Citric Acid Cycle; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glioblastoma; Glutamic Acid; Glutaminase; Humans; Neoplastic Stem Cells; Signal Transduction; Thiadiazoles

2020
Bioinformatics and machine learning methodologies to identify the effects of central nervous system disorders on glioblastoma progression.
    Briefings in bioinformatics, 2021, 09-02, Volume: 22, Issue:5

    Topics: Atlases as Topic; Brain Neoplasms; Central Nervous System; Computational Biology; Datasets as Topic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Ontology; Gene Regulatory Networks; Glioblastoma; Glutamic Acid; Humans; Kaplan-Meier Estimate; Machine Learning; Molecular Sequence Annotation; Neoplasm Proteins; Proportional Hazards Models; Signal Transduction

2021
Association of preoperative seizures with tumor metabolites quantified by magnetic resonance spectroscopy in gliomas.
    Scientific reports, 2021, 04-12, Volume: 11, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytes; Brain Neoplasms; Female; Glioma; Glutamic Acid; Humans; Isocitrate Dehydrogenase; Magnetic Resonance Spectroscopy; Male; Metabolome; Middle Aged; Multivariate Analysis; Mutation; Oligodendroglia; Seizures; Survival Analysis; Young Adult

2021
The investigation of glutamate transporter 1 (GLT-1) degradation pathway in glioblastoma cells.
    Molecular biology reports, 2021, Volume: 48, Issue:4

    Topics: Brain Neoplasms; Cell Line, Tumor; Excitatory Amino Acid Transporter 2; Glioblastoma; Glutamic Acid; Humans; Proteolysis; Ubiquitin

2021
Blood glutamate scavengers increase pro-apoptotic signaling and reduce metastatic melanoma growth in-vivo.
    Scientific reports, 2021, 07-19, Volume: 11, Issue:1

    Topics: Animals; Apoptosis; Aspartate Aminotransferase, Cytoplasmic; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Therapy, Combination; Glioblastoma; Glutamic Acid; Humans; Melanoma; Mice; Mice, Inbred C57BL; Molecular Targeted Therapy; Oxaloacetic Acid; Recombinant Proteins; Signal Transduction; Tumor Microenvironment

2021
Synergy between glutamate modulation and anti-programmed cell death protein 1 immunotherapy for glioblastoma.
    Journal of neurosurgery, 2022, Feb-01, Volume: 136, Issue:2

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glutamic Acid; Immunotherapy; Mice; Mice, Inbred C57BL; Tumor Microenvironment

2022
Microglia-Derived Small Extracellular Vesicles Reduce Glioma Growth by Modifying Tumor Cell Metabolism and Enhancing Glutamate Clearance through miR-124.
    Cells, 2021, 08-12, Volume: 10, Issue:8

    Topics: Animals; Antagomirs; Brain Neoplasms; Cell Proliferation; Cells, Cultured; Excitatory Amino Acid Transporter 2; Extracellular Vesicles; Glioma; Glutamic Acid; Interferon-gamma; Kaplan-Meier Estimate; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; MicroRNAs; Nitric Oxide; Up-Regulation

2021
ATF4 promotes angiogenesis and neuronal cell death and confers ferroptosis in a xCT-dependent manner.
    Oncogene, 2017, 10-05, Volume: 36, Issue:40

    Topics: Activating Transcription Factor 4; Amino Acid Transport System y+; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glioma; Glutamic Acid; Humans; Iron; Neovascularization, Pathologic; Neurons

2017
Measurement of
    FEBS letters, 2017, Volume: 591, Issue:21

    Topics: Acetates; Brain Neoplasms; Carbon Isotopes; Female; Glutamic Acid; Glutamine; Humans; Male

2017
In vivo characterization of brain metabolism by
    International journal of cancer, 2018, 07-01, Volume: 143, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Animals; Aspartic Acid; Brain; Brain Neoplasms; Cell Line, Tumor; Fluorodeoxyglucose F18; gamma-Aminobutyric Acid; Glioma; Glucose; Glutamic Acid; Humans; Male; Mice; Neoplasm Transplantation; Oxidation-Reduction; Positron-Emission Tomography; Proton Magnetic Resonance Spectroscopy; Repressor Proteins

2018
BRAF activating mutations involving the β3-αC loop in V600E-negative anaplastic pleomorphic xanthoastrocytoma.
    Acta neuropathologica communications, 2018, 03-15, Volume: 6, Issue:1

    Topics: Astrocytoma; Brain Neoplasms; Child, Preschool; Glutamic Acid; Humans; Male; Mutation; Proto-Oncogene Proteins B-raf; Valine; Young Adult

2018
Isocitrate dehydrogenase 1-mutated human gliomas depend on lactate and glutamate to alleviate metabolic stress.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:1

    Topics: 4-Aminobutyrate Transaminase; Animals; Brain Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Glutamate Dehydrogenase; Glutamic Acid; Glutaminase; Humans; Isocitrate Dehydrogenase; Lactic Acid; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Neoplasm Invasiveness; Stress, Physiological; Succinate-Semialdehyde Dehydrogenase; Transcriptome; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2019
Spatially Resolved Bioenergetic and Genetic Reprogramming Through the Brain of Rats Bearing Implanted C6 Gliomas As Detected by Multinuclear High-Resolution Magic Angle Spinning and Genomic Analysis.
    Journal of proteome research, 2018, 09-07, Volume: 17, Issue:9

    Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Biopsy; Brain Neoplasms; Carbon Isotopes; Caudate Nucleus; Cellular Reprogramming; Female; Gene Expression Profiling; Gene Expression Regulation; Glioma; Glucose; Glutamic Acid; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lactic Acid; Magnetic Resonance Imaging; Neoplasm Transplantation; Oxidative Phosphorylation; Rats; Rats, Wistar; Transcription Factors; Transplantation, Heterologous

2018
Epidermal growth factor receptor promotes glioma progression by regulating xCT and GluN2B-containing N-methyl-d-aspartate-sensitive glutamate receptor signaling.
    Cancer science, 2018, Volume: 109, Issue:12

    Topics: Amino Acid Transport System y+; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Disease Progression; Dizocilpine Maleate; Drug Synergism; Epidermal Growth Factor; ErbB Receptors; Glioma; Glutamic Acid; Humans; Mice; Neoplasm Transplantation; Phosphorylation; Protein Domains; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sulfasalazine

2018
AMPA receptor antagonist perampanel affects glioblastoma cell growth and glutamate release in vitro.
    PloS one, 2019, Volume: 14, Issue:2

    Topics: Anticonvulsants; Antineoplastic Agents; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Epilepsy; Glioblastoma; Glutamic Acid; Humans; Nitriles; Pyridones; Receptors, AMPA; Seizures; Up-Regulation; Valproic Acid

2019
Glutamate weighted imaging contrast in gliomas with 7 Tesla magnetic resonance imaging.
    NeuroImage. Clinical, 2019, Volume: 22

    Topics: Adult; Brain Neoplasms; Epilepsy; Female; Glioma; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged

2019
Dysembryoplastic neuroepithelial tumors share with pleomorphic xanthoastrocytomas and gangliogliomas BRAF(V600E) mutation and expression.
    Brain pathology (Zurich, Switzerland), 2013, Volume: 23, Issue:5

    Topics: Adolescent; Antigens, CD34; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; Female; Ganglioglioma; Glutamic Acid; Humans; Infant; Male; Neoplasms, Neuroepithelial; Proto-Oncogene Proteins B-raf; Valine; Young Adult

2013
BRAF V600E mutation identifies a subset of low-grade diffusely infiltrating gliomas in adults.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, May-10, Volume: 31, Issue:14

    Topics: Adult; Astrocytoma; Brain Neoplasms; Female; Glioma; Glutamic Acid; Humans; Immunohistochemistry; Male; Neoplasm Grading; Point Mutation; Proto-Oncogene Proteins B-raf; Valine

2013
A comparative study of short- and long-TE ¹H MRS at 3 T for in vivo detection of 2-hydroxyglutarate in brain tumors.
    NMR in biomedicine, 2013, Volume: 26, Issue:10

    Topics: Adult; Aspartic Acid; Brain Neoplasms; gamma-Aminobutyric Acid; Glioma; Glutamic Acid; Glutamine; Glutarates; Humans; Isocitrate Dehydrogenase; Magnetic Resonance Spectroscopy; Middle Aged; Mutation; Phantoms, Imaging; Protons; Young Adult

2013
Absent response of intracranial melanoma metastases harboring BRAF V600E sequence variation to vemurafenib.
    Mayo Clinic proceedings, 2013, Volume: 88, Issue:12

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Fatal Outcome; Glutamic Acid; Humans; Ileal Neoplasms; Immunohistochemistry; Indoles; Magnetic Resonance Imaging; Male; Melanoma; Proto-Oncogene Proteins B-raf; Skin Neoplasms; Sulfonamides; Treatment Failure; Valine; Vemurafenib

2013
Intratumoral heterogeneity of genomic imbalance in a case of epithelioid glioblastoma with BRAF V600E mutation.
    Brain pathology (Zurich, Switzerland), 2014, Volume: 24, Issue:3

    Topics: Brain Neoplasms; DNA Mutational Analysis; Glioblastoma; Glutamic Acid; Humans; Isocitrate Dehydrogenase; Male; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins B-raf; Valine; Young Adult

2014
Glutamate quantification in patients with supratentorial gliomas using chemical shift imaging.
    NMR in biomedicine, 2014, Volume: 27, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Demography; Female; Glioma; Glutamic Acid; Humans; Linear Models; Magnetic Resonance Imaging; Male; Middle Aged; Phantoms, Imaging; Supratentorial Neoplasms; Young Adult

2014
Hyperpolarized [1-13C] glutamate: a metabolic imaging biomarker of IDH1 mutational status in glioma.
    Cancer research, 2014, Aug-15, Volume: 74, Issue:16

    Topics: Animals; Biomarkers, Tumor; Brain Neoplasms; Carbon-13 Magnetic Resonance Spectroscopy; Cell Line, Tumor; Glioma; Glutamic Acid; Humans; Isocitrate Dehydrogenase; Ketoglutaric Acids; Male; Mutation; Radiopharmaceuticals; Rats; Rats, Nude; Transaminases

2014
Epithelioid glioblastoma arising from pleomorphic xanthoastrocytoma with the BRAF V600E mutation.
    Brain tumor pathology, 2014, Volume: 31, Issue:3

    Topics: Amino Acid Substitution; Astrocytoma; Brain Neoplasms; Child; Female; Glioblastoma; Glutamic Acid; Humans; Magnetic Resonance Imaging; Mutation; Neoplasms, Second Primary; Proto-Oncogene Proteins B-raf; Time Factors; Valine

2014
Kynurenic acid inhibits proliferation and migration of human glioblastoma T98G cells.
    Pharmacological reports : PR, 2014, Volume: 66, Issue:1

    Topics: Adult; Aged; Benzodiazepines; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Glioblastoma; Glutamic Acid; Humans; Kynurenic Acid; Male; Middle Aged

2014
Noninvasive detection of glutamate predicts survival in pediatric medulloblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Sep-01, Volume: 20, Issue:17

    Topics: Adolescent; Biomarkers, Tumor; Brain Neoplasms; Child; Child, Preschool; Female; Glutamic Acid; Humans; Kaplan-Meier Estimate; Magnetic Resonance Spectroscopy; Male; Medulloblastoma; Precision Medicine; Prognosis; Radiography

2014
Successful Treatment of a Progressive BRAF V600E-Mutated Anaplastic Pleomorphic Xanthoastrocytoma With Vemurafenib Monotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, Apr-01, Volume: 34, Issue:10

    Topics: Adult; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Drug Administration Schedule; Drug Eruptions; Frontal Lobe; Glutamic Acid; Humans; Indoles; Magnetic Resonance Imaging; Male; Mutation; Neoplasm Staging; Proto-Oncogene Proteins B-raf; Sulfonamides; Temporal Lobe; Treatment Outcome; Valine; Vemurafenib; Xanthomatosis

2016
Hominoid-specific enzyme GLUD2 promotes growth of IDH1R132H glioma.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Sep-30, Volume: 111, Issue:39

    Topics: Amino Acid Substitution; Animals; Brain Neoplasms; Cell Line, Tumor; Female; Gene Knockdown Techniques; Genes, p53; Glioma; Glutamate Dehydrogenase; Glutamic Acid; Humans; Isocitrate Dehydrogenase; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Mutant Proteins; Neoplastic Stem Cells; Receptors, Glutamate

2014
Fluorescent carbonaceous nanodots for noninvasive glioma imaging after angiopep-2 decoration.
    Bioconjugate chemistry, 2014, Dec-17, Volume: 25, Issue:12

    Topics: Animals; Brain Neoplasms; Chemistry Techniques, Synthetic; Diagnostic Imaging; Endosomes; Fluorescent Dyes; Glioma; Glucose; Glutamic Acid; Male; Mice, Inbred BALB C; Particle Size; Peptides; Quantum Dots; Tissue Distribution; Tumor Cells, Cultured

2014
Why glioma patients seize: adding more pathological GABA to the glutamate hypothesis.
    Neurosurgery, 2014, Volume: 75, Issue:6

    Topics: Animals; Brain Neoplasms; gamma-Aminobutyric Acid; Glioma; Glutamic Acid; Humans; Seizures

2014
Acetate is a bioenergetic substrate for human glioblastoma and brain metastases.
    Cell, 2014, Dec-18, Volume: 159, Issue:7

    Topics: Acetate-CoA Ligase; Acetates; Animals; Brain Neoplasms; Citric Acid Cycle; Disease Models, Animal; Glioblastoma; Glutamic Acid; Humans; Mice; Neoplasm Metastasis

2014
Cell-density-dependent manifestation of partial characteristics for neuronal precursors in a newly established human gliosarcoma cell line.
    In vitro cellular & developmental biology. Animal, 2015, Volume: 51, Issue:4

    Topics: Animals; Biomarkers; Brain Neoplasms; Cell Count; Cell Line, Tumor; Gliosarcoma; Glutamic Acid; Glutaminase; Humans; Karyotype; Male; Mice, Inbred BALB C; Middle Aged; Nestin; Neurons; SOXB1 Transcription Factors; Xenograft Model Antitumor Assays

2015
Compensatory glutamine metabolism promotes glioblastoma resistance to mTOR inhibitor treatment.
    The Journal of clinical investigation, 2015, Volume: 125, Issue:4

    Topics: Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Benzophenanthridines; Brain Neoplasms; Cell Line, Tumor; Citric Acid Cycle; Drug Resistance, Neoplasm; Drug Synergism; Energy Metabolism; Gas Chromatography-Mass Spectrometry; Glioblastoma; Glutamic Acid; Glutaminase; Glutamine; Glycolysis; Humans; Indoles; Ketoglutaric Acids; Magnetic Resonance Spectroscopy; Male; Metabolome; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Targeted Therapy; Neoplasm Proteins; Protein Kinase Inhibitors; Purines; RNA, Small Interfering; Rotarod Performance Test; Signal Transduction; Temporal Lobe; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays

2015
The peroxisome proliferator activated receptor gamma agonist pioglitazone increases functional expression of the glutamate transporter excitatory amino acid transporter 2 (EAAT2) in human glioblastoma cells.
    Oncotarget, 2015, Aug-28, Volume: 6, Issue:25

    Topics: Anilides; Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 2; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioblastoma; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Neoplasm Transplantation; Pioglitazone; PPAR gamma; Rats; Rats, Wistar; Seizures; Thiazolidinediones

2015
Glioblastoma cells induce differential glutamatergic gene expressions in human tumor-associated microglia/macrophages and monocyte-derived macrophages.
    Cancer biology & therapy, 2015, Volume: 16, Issue:8

    Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Astrocytes; Brain Neoplasms; Calcium-Binding Proteins; CD11b Antigen; Coculture Techniques; DNA-Binding Proteins; Gene Expression Regulation; Glioblastoma; Glutamic Acid; Humans; Leukocyte Common Antigens; Macrophages; Microfilament Proteins; Microglia; Receptors, AMPA; Tumor Cells, Cultured

2015
Gas1 Knockdown Increases the Neuroprotective Effect of Glial Cell-Derived Neurotrophic Factor Against Glutamate-Induced Cell Injury in Human SH-SY5Y Neuroblastoma Cells.
    Cellular and molecular neurobiology, 2016, Volume: 36, Issue:4

    Topics: Brain Neoplasms; Caspase 3; Caspase 9; Cell Cycle Proteins; Cell Death; Cell Survival; Fluorometry; Gene Knockdown Techniques; Gene Silencing; Glial Cell Line-Derived Neurotrophic Factor; Glutamic Acid; GPI-Linked Proteins; Humans; Mitochondria; Neuroblastoma; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction

2016
High-Throughput Assay Development for Cystine-Glutamate Antiporter (xc-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma Cells.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Amino Acid Transport System y+; Benzoates; Brain Neoplasms; Cell Line, Tumor; Cystine; Databases, Chemical; Gene Expression Regulation, Neoplastic; Glioma; Glutamic Acid; Glycine; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Models, Biological; RNA, Messenger; Sulfasalazine; Time Factors

2015
Neurodegeneration and the Brain Tumor Microenvironment. [corrected].
    Current neuropharmacology, 2015, Volume: 13, Issue:2

    Topics: Amino Acid Transport Systems; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain Neoplasms; Glutamic Acid; Humans; Models, Molecular; Nerve Degeneration; Reactive Oxygen Species; Sulfasalazine; Transient Receptor Potential Channels

2015
Alterations in cellular metabolome after pharmacological inhibition of Notch in glioblastoma cells.
    International journal of cancer, 2016, Mar-01, Volume: 138, Issue:5

    Topics: Brain Neoplasms; Cell Line, Tumor; Cyclic S-Oxides; Glioblastoma; Glutamic Acid; Glutaminase; Homeostasis; Humans; Metabolome; Receptors, Notch; Thiadiazoles

2016
Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma.
    Nature cell biology, 2015, Volume: 17, Issue:12

    Topics: Animals; Astrocytes; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Citric Acid Cycle; Coculture Techniques; Female; Glioblastoma; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Humans; Male; Mice, Inbred NOD; Mice, SCID; Models, Biological; Neoplastic Stem Cells; Nucleotides; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Transplantation, Heterologous

2015
Recurrent ganglioglioma in adults treated with BRAF inhibitors.
    CNS oncology, 2016, Volume: 5, Issue:1

    Topics: Adult; Brain Neoplasms; Enzyme Inhibitors; Female; Ganglioglioma; Glutamic Acid; Humans; Imidazoles; Male; Middle Aged; Mutation; Oximes; Proto-Oncogene Proteins B-raf; Valine

2016
Pilot Preclinical and Clinical Evaluation of (4S)-4-(3-[18F]Fluoropropyl)-L-Glutamate (18F-FSPG) for PET/CT Imaging of Intracranial Malignancies.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: Adult; Aged; Animals; Brain Neoplasms; Case-Control Studies; Cell Line, Tumor; Disease Models, Animal; Female; Fluorodeoxyglucose F18; Glioblastoma; Glutamic Acid; Heterografts; Humans; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Tomography, X-Ray Computed; Tyrosine

2016
The EGF Receptor Promotes the Malignant Potential of Glioma by Regulating Amino Acid Transport System xc(-).
    Cancer research, 2016, 05-15, Volume: 76, Issue:10

    Topics: Amino Acid Transport System y+; Animals; Antioxidants; Apoptosis; Brain Neoplasms; Cell Membrane; Cell Movement; Cell Proliferation; Cystine; ErbB Receptors; Gene Expression Regulation, Neoplastic; Glioma; Glutamic Acid; Humans; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Reactive Oxygen Species; Sulfasalazine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2016
Diagnostic value of glutamate with 2-hydroxyglutarate in magnetic resonance spectroscopy for IDH1 mutant glioma.
    Neuro-oncology, 2016, Volume: 18, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Brain Neoplasms; Glioma; Glutamate Dehydrogenase; Glutamic Acid; Glutarates; Humans; Isocitrate Dehydrogenase; Magnetic Resonance Spectroscopy; Metabolomics; Middle Aged; Mutation; Sensitivity and Specificity; Transaminases; Young Adult

2016
Refined modelling of the short-T2 signal component and ensuing detection of glutamate and glutamine in short-TE, localised, (1) H MR spectra of human glioma measured at 3 T.
    NMR in biomedicine, 2016, Volume: 29, Issue:7

    Topics: Adult; Algorithms; Biomarkers, Tumor; Brain Neoplasms; Computer Simulation; Female; Glioma; Glutamic Acid; Glutamine; Humans; Male; Middle Aged; Models, Biological; Models, Chemical; Proton Magnetic Resonance Spectroscopy; Reproducibility of Results; Sensitivity and Specificity; Signal Processing, Computer-Assisted

2016
Advanced MRI increases the diagnostic accuracy of recurrent glioblastoma: Single institution thresholds and validation of MR spectroscopy and diffusion weighted MR imaging.
    NeuroImage. Clinical, 2016, Volume: 11

    Topics: Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Cohort Studies; Diffusion Magnetic Resonance Imaging; Female; Glioblastoma; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Spectroscopy; Male; Middle Aged; ROC Curve; Statistics, Nonparametric

2016
Integrative Network-based Analysis of Magnetic Resonance Spectroscopy and Genome Wide Expression in Glioblastoma multiforme.
    Scientific reports, 2016, 06-28, Volume: 6

    Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Neoplasms; Computational Biology; Creatine; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genome-Wide Association Study; Glioblastoma; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neoplasm Proteins; Neurons; Oligodendroglia; Prognosis; Prospective Studies; Survival Analysis

2016
Glutamate-Mediated Blood-Brain Barrier Opening: Implications for Neuroprotection and Drug Delivery.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, 07-20, Volume: 36, Issue:29

    Topics: 4-Aminopyridine; Adult; Aged; Animals; Blood-Brain Barrier; Brain Neoplasms; Disease Models, Animal; Double-Blind Method; Female; Glioblastoma; Glutamic Acid; Humans; Male; Middle Aged; Neuroprotective Agents; Permeability; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Seizures; Stroke; Treatment Outcome

2016
Compromised GABAergic inhibition contributes to tumor-associated epilepsy.
    Epilepsy research, 2016, Volume: 126

    Topics: Animals; Brain; Brain Neoplasms; Bumetanide; Cell Line, Tumor; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Glioma; Glutamic Acid; K Cl- Cotransporters; Male; Mice, Inbred C57BL; Mice, Nude; Mice, Transgenic; Phosphorylation; Rats; Sodium Potassium Chloride Symporter Inhibitors; Solute Carrier Family 12, Member 2; Symporters; Tissue Culture Techniques

2016
Activating NRF1-BRAF and ATG7-RAF1 fusions in anaplastic pleomorphic xanthoastrocytoma without BRAF p.V600E mutation.
    Acta neuropathologica, 2016, Volume: 132, Issue:5

    Topics: Adolescent; Astrocytoma; Brain Neoplasms; DNA Helicases; Exons; Female; Glutamic Acid; Humans; Male; Mitogen-Activated Protein Kinase Kinases; Mutation; Nuclear Proteins; Nuclear Respiratory Factor 1; Oncogene Fusion; Proto-Oncogene Proteins B-raf; raf Kinases; Signal Transduction; Time Factors; Transcription Factors; Tripartite Motif-Containing Protein 28; Tumor Suppressor Protein p53; Valine; World Health Organization; Young Adult

2016
Radiotherapy induces an immediate inflammatory reaction in malignant glioma: a clinical microdialysis study.
    Journal of neuro-oncology, 2017, Volume: 131, Issue:1

    Topics: Aged; Aged, 80 and over; Brain Neoplasms; Cytokines; Female; Glioma; Glucose; Glutamic Acid; Glycerol; Humans; Inflammation; Male; Microdialysis; Middle Aged; Radiotherapy; Statistics, Nonparametric

2017
Glutamine Metabolism in Gliomas.
    Advances in neurobiology, 2016, Volume: 13

    Topics: Brain Neoplasms; Cell Proliferation; Glioma; Glutamic Acid; Glutaminase; Glutamine; Humans; Neoplasm Invasiveness

2016
BRAF V600E mutation in epilepsy-associated glioneuronal tumors: Prevalence and correlation with clinical features in a Chinese population.
    Seizure, 2017, Volume: 45

    Topics: Adolescent; Adult; Brain; Brain Neoplasms; Child; Child, Preschool; China; Cohort Studies; Electroencephalography; Epilepsy; Female; Glioma; Glutamic Acid; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins B-raf; Statistics as Topic; Statistics, Nonparametric; Valine; Young Adult

2017
Changes in cerebral metabolism during ketogenic diet in patients with primary brain tumors:
    Journal of neuro-oncology, 2017, Volume: 132, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Immunological; Aspartic Acid; Bevacizumab; Brain Neoplasms; Cerebral Cortex; Diet, Ketogenic; Female; Glucose; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nutrition Assessment; Protons; Severity of Illness Index

2017
In search of druggable targets for GBM amino acid metabolism.
    BMC cancer, 2017, 02-28, Volume: 17, Issue:1

    Topics: Amino Acids; Brain Neoplasms; Databases, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioblastoma; Glutamic Acid; Humans; Metabolic Networks and Pathways; Prognosis; Survival Analysis; Urea

2017
Glucose metabolites, glutamate and glycerol in malignant glioma tumours during radiotherapy.
    Journal of neuro-oncology, 2008, Volume: 90, Issue:1

    Topics: Brain Neoplasms; Glioma; Glucose; Glutamic Acid; Glycerol; Humans; Microdialysis; Radiosurgery

2008
Protein phosphatase 1, protein phosphatase 2A, and calcineurin play a role in estrogen-mediated neuroprotection.
    Endocrinology, 2008, Volume: 149, Issue:10

    Topics: Animals; Brain Neoplasms; Calcineurin; Calcineurin Inhibitors; Cell Line, Tumor; Cell Survival; Cyclosporine; Dicarboxylic Acids; Drug Interactions; Enzyme Inhibitors; Estrogens; Glioma; Glutamic Acid; Mice; Neurons; Neuroprotective Agents; Neurotoxins; Okadaic Acid; Oxidative Stress; Protein Phosphatase 1; Protein Phosphatase 2; Rats; Stroke

2008
Two distinct tumor phenotypes isolated from glioblastomas show different MRS characteristics.
    NMR in biomedicine, 2008, Volume: 21, Issue:8

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Choline; Glioblastoma; Glutamic Acid; Magnetic Resonance Spectroscopy; Phenotype; Rats; Rats, Nude

2008
Cerebral metabolism during air transport of patients after surgery for malignant glioma.
    Aviation, space, and environmental medicine, 2008, Volume: 79, Issue:7

    Topics: Air Ambulances; Brain; Brain Neoplasms; Glioma; Glucose; Glutamic Acid; Glycerol; Humans; Lactic Acid; Microdialysis; Pyruvic Acid; Transportation of Patients

2008
Cellular localization of metabotropic glutamate receptors in cortical tubers and subependymal giant cell tumors of tuberous sclerosis complex.
    Neuroscience, 2008, Sep-22, Volume: 156, Issue:1

    Topics: Adolescent; Adult; Astrocytes; Biomarkers, Tumor; Brain Neoplasms; Cerebral Cortex; Child; Child, Preschool; Female; Giant Cells; Glioma, Subependymal; Glutamic Acid; Humans; Immunohistochemistry; Infant; Male; Neurons; Protein Kinases; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; TOR Serine-Threonine Kinases; Tuberous Sclerosis; Young Adult

2008
Short echo spectroscopic imaging of the human brain at 7T using transceiver arrays.
    Magnetic resonance in medicine, 2009, Volume: 62, Issue:1

    Topics: Biomarkers, Tumor; Brain; Brain Neoplasms; Equipment Design; Equipment Failure Analysis; Glutamic Acid; Humans; Image Enhancement; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Magnetics; Oligodendroglioma; Reproducibility of Results; Sensitivity and Specificity; Transducers

2009
MRI and MRS of human brain tumors.
    Methods in molecular biology (Clifton, N.J.), 2009, Volume: 520

    Topics: Brain Neoplasms; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy

2009
The x(c)(-) cystine/glutamate antiporter (xCT) as a potential target for therapy of cancer: yet another cytotoxic anticancer approach?
    Journal of cellular physiology, 2009, Volume: 220, Issue:2

    Topics: Amino Acid Transport System y+; Antineoplastic Agents; Antiporters; Brain Neoplasms; Cystine; Glutamic Acid; Humans; Protein Subunits

2009
Attenuated AMPA receptor expression allows glioblastoma cell survival in glutamate-rich environment.
    PloS one, 2009, Jun-18, Volume: 4, Issue:6

    Topics: Animals; Brain; Brain Neoplasms; Calcium; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Glioblastoma; Glutamic Acid; Humans; Immunohistochemistry; Mice; Receptors, AMPA; Sodium

2009
Dual cross-talk between nitric oxide and D-serine in astrocytes and neurons in the brain.
    Central nervous system agents in medicinal chemistry, 2009, Volume: 9, Issue:4

    Topics: Aging; Animals; Animals, Newborn; Astrocytes; Brain; Brain Neoplasms; Cells, Cultured; Cytokines; Glutamic Acid; Neuronal Plasticity; Neurons; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Rats, Wistar; Receptor Cross-Talk; Serine; Stress, Physiological

2009
Dissection of mitogenic and neurodegenerative actions of cystine and glutamate in malignant gliomas.
    Oncogene, 2011, Jan-06, Volume: 30, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Growth Processes; Cell Line, Tumor; Cystine; Down-Regulation; Glioma; Glutamic Acid; Humans; Mice; Rats; Receptors, AMPA; Signal Transduction; Transfection

2011
Stripe-like increase of rCBV beyond the visible border of glioblastomas: site of tumor infiltration growing after neurosurgery.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:3

    Topics: Adult; Aged; Asparagine; Blood Volume; Brain Neoplasms; Cerebrovascular Circulation; Contrast Media; Creatine; Female; Glioblastoma; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurosurgical Procedures; Postoperative Complications; Reproducibility of Results; Statistics, Nonparametric; Time Factors; Tritium; Young Adult

2011
Impaired hippocampal synaptic plasticity in C6 glioma-bearing rats.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:3

    Topics: Animals; Body Weight; Brain Neoplasms; Cell Line, Tumor; Chromatography, High Pressure Liquid; Disease Models, Animal; Electric Stimulation; Excitatory Postsynaptic Potentials; Exploratory Behavior; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glioma; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Synaptic Transmission

2011
[2,4-(13)C]β-hydroxybutyrate metabolism in astrocytes and C6 glioblastoma cells.
    Neurochemical research, 2011, Volume: 36, Issue:8

    Topics: 3-Hydroxybutyric Acid; Animals; Aspartic Acid; Astrocytes; Brain Neoplasms; Citric Acid Cycle; Diet, Ketogenic; Glioblastoma; Glucose; Glutamic Acid; Glutamine; Humans; Ketone Bodies; Lactic Acid; Mice; Tumor Cells, Cultured

2011
Oncogene AEG-1 promotes glioma-induced neurodegeneration by increasing glutamate excitotoxicity.
    Cancer research, 2011, Oct-15, Volume: 71, Issue:20

    Topics: Animals; Astrocytes; Brain; Brain Neoplasms; Cell Adhesion Molecules; Cell Line, Tumor; CREB-Binding Protein; Excitatory Amino Acid Transporter 2; Glioma; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Membrane Proteins; Nerve Degeneration; Oncogenes; Promoter Regions, Genetic; Rats; RNA-Binding Proteins; YY1 Transcription Factor

2011
Glutamate release by primary brain tumors induces epileptic activity.
    Nature medicine, 2011, Sep-11, Volume: 17, Issue:10

    Topics: Amino Acid Transport System y+; Analysis of Variance; Animals; Brain Neoplasms; Cell Transplantation; Electroencephalography; Electrophysiology; Epilepsy; Glioma; Glutamic Acid; Humans; Mice; Mice, SCID; Sulfasalazine

2011
Glioma-related seizures: glutamate is the key.
    Nature medicine, 2011, Oct-11, Volume: 17, Issue:10

    Topics: Animals; Brain Neoplasms; Epilepsy; Glioma; Glutamic Acid; Humans

2011
Immunohistochemical testing of BRAF V600E status in 1,120 tumor tissue samples of patients with brain metastases.
    Acta neuropathologica, 2012, Volume: 123, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Female; Genetic Predisposition to Disease; Glutamic Acid; HEK293 Cells; Humans; Immunohistochemistry; Male; Middle Aged; Point Mutation; Proto-Oncogene Proteins B-raf; Valine; Young Adult

2012
Glutamate and tumor-associated epilepsy.
    Oncotarget, 2011, Volume: 2, Issue:11

    Topics: Animals; Brain Neoplasms; Epilepsy; Glutamic Acid; Humans

2011
Magnetic resonance imaging of glutamate.
    Nature medicine, 2012, Jan-22, Volume: 18, Issue:2

    Topics: Adult; Animals; Brain; Brain Neoplasms; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Imaging; Male; Neuroimaging; Rats

2012
Glucose metabolism via the pentose phosphate pathway, glycolysis and Krebs cycle in an orthotopic mouse model of human brain tumors.
    NMR in biomedicine, 2012, Volume: 25, Issue:10

    Topics: Animals; Brain Neoplasms; Carcinoma, Renal Cell; Citric Acid Cycle; Disease Models, Animal; gamma-Aminobutyric Acid; Glioblastoma; Glucose; Glutamate Decarboxylase; Glutamic Acid; Glycolysis; Humans; Kidney Neoplasms; Lactic Acid; Magnetic Resonance Imaging; Mice; Pentose Phosphate Pathway; Positron-Emission Tomography; Xenograft Model Antitumor Assays

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Glioma; Glutamic Acid; Humans; Male; Mice; Mice, Nude; Oxaloacetic Acid; Rats; Rats, Sprague-Dawley; Temozolomide; Tumor Burden

2012
Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo.
    Cell metabolism, 2012, Jun-06, Volume: 15, Issue:6

    Topics: Animals; Brain Neoplasms; Glioblastoma; Gluconeogenesis; Glucose; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; Glycolysis; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Mitochondria; Neoplasm Transplantation; Neostriatum; Oxidation-Reduction; Phenotype; Pyruvate Carboxylase; Statistics, Nonparametric; Tumor Cells, Cultured

2012
Human glioma cells induce hyperexcitability in cortical networks.
    Epilepsia, 2012, Volume: 53, Issue:8

    Topics: Action Potentials; Animals; Brain; Brain Neoplasms; Disease Models, Animal; Electrophysiology; Female; Glioma; Glutamic Acid; Humans; Mice; Mice, SCID; Neoplasm Transplantation; Nerve Net; Seizures; Sulfasalazine; Tumor Cells, Cultured

2012
Effects of 18-kDa translocator protein knockdown on gene expression of glutamate receptors, transporters, and metabolism, and on cell viability affected by glutamate.
    Pharmacogenetics and genomics, 2012, Volume: 22, Issue:8

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioblastoma; Glutamic Acid; Humans; Oligonucleotide Array Sequence Analysis; Rats; Receptors, GABA; Receptors, Glutamate; RNA, Small Interfering

2012
Fluoxetine (prozac) and serotonin act on excitatory synaptic transmission to suppress single layer 2/3 pyramidal neuron-triggered cell assemblies in the human prefrontal cortex.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Nov-14, Volume: 32, Issue:46

    Topics: Adult; Aged; Brain Neoplasms; Excitatory Amino Acids; Excitatory Postsynaptic Potentials; Female; Fluoxetine; Glutamic Acid; Humans; Male; Middle Aged; Nerve Net; Prefrontal Cortex; Pyramidal Cells; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Serotonin; Synaptic Transmission

2012
Calretinin and calbindin D-28k, but not parvalbumin protect against glutamate-induced delayed excitotoxicity in transfected N18-RE 105 neuroblastoma-retina hybrid cells.
    Brain research, 2002, Aug-02, Volume: 945, Issue:2

    Topics: Animals; Blotting, Western; Brain Neoplasms; Calbindin 2; Calbindins; Cell Division; Cell Line; Clone Cells; Coloring Agents; Enzyme-Linked Immunosorbent Assay; Glutamic Acid; Hybrid Cells; Immunohistochemistry; Mice; Neuroblastoma; Parvalbumins; Plasmids; Rats; Retina; S100 Calcium Binding Protein G; Tetrazolium Salts; Thiazoles; Transfection

2002
Paving new pathways.
    Nature medicine, 2002, Volume: 8, Issue:9

    Topics: Antineoplastic Agents; Brain Neoplasms; Connexin 43; Excitatory Amino Acid Transporter 2; Glioma; Glutamic Acid; Receptors, AMPA; Receptors, Glutamate

2002
Adult primitive neuroectodermal tumor: proton MR spectroscopic findings with possible application for differential diagnosis.
    Radiology, 2002, Volume: 225, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Astrocytoma; Brain; Brain Neoplasms; Diagnosis, Differential; Female; Glioblastoma; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Meningeal Neoplasms; Meningioma; Middle Aged; Neuroectodermal Tumors, Primitive; Prospective Studies; Retrospective Studies

2002
1H MR spectroscopy of mesial temporal lobe epilepsies treated with Gamma knife.
    European radiology, 2003, Volume: 13, Issue:5

    Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Epilepsy, Temporal Lobe; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Humans; Lipid Metabolism; Lipids; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Postoperative Complications; Radiation Injuries; Radiation Tolerance; Radiosurgery; Seizures; Time Factors; Treatment Failure

2003
A chemometric approach for brain tumor classification using magnetic resonance imaging and spectroscopy.
    Analytical chemistry, 2003, Oct-15, Volume: 75, Issue:20

    Topics: Aspartic Acid; Brain; Brain Chemistry; Brain Neoplasms; Cerebrospinal Fluid; Choline; Creatine; Discriminant Analysis; Fatty Acids; Glioma; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Inositol; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Patient Selection; Principal Component Analysis; Probability; Sensitivity and Specificity; Statistical Distributions

2003
Polyamine uptake in cultured cerebellar granule neurons.
    Neurochemistry international, 2004, Volume: 44, Issue:7

    Topics: Animals; Astrocytes; Biogenic Polyamines; Brain Neoplasms; Cell Line, Tumor; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Glutamic Acid; Kinetics; Membrane Potentials; Mice; Neuroblastoma; Neurons; Putrescine; Spermidine; Spermine; Synaptosomes

2004
Glutamate transporter cluster formation in astrocytic processes regulates glutamate uptake activity.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Jul-14, Volume: 24, Issue:28

    Topics: Actin Cytoskeleton; Actins; Animals; Astrocytes; Brain Neoplasms; Cell Compartmentation; Cell Line, Tumor; Cell Surface Extensions; Excitatory Amino Acid Transporter 2; Glioma; Glutamic Acid; Green Fluorescent Proteins; Mice; Protein Transport; Recombinant Fusion Proteins; Sucrose; Tetradecanoylphorbol Acetate

2004
Gliotoxins disrupt alanine metabolism and glutathione production in C6 glioma cells: a 13C NMR spectroscopic study.
    Neurochemistry international, 2004, Volume: 45, Issue:8

    Topics: Alanine; Alanine Transaminase; Brain Neoplasms; Cell Line, Tumor; Dicarboxylic Acids; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; gamma-Glutamyltransferase; Glioma; Gliotoxin; Glutamic Acid; Glutathione; Glycine; Humans; Immunosuppressive Agents; Indicators and Reagents; Lactic Acid; Magnetic Resonance Spectroscopy; Pyrrolidines

2004
Reduced glutamine synthetase in hippocampal areas with neuron loss in temporal lobe epilepsy.
    Neurology, 2005, Jan-25, Volume: 64, Issue:2

    Topics: Adult; Aged; Anterior Temporal Lobectomy; Anticonvulsants; Biomarkers; Brain Neoplasms; Cell Death; Combined Modality Therapy; Epilepsy, Temporal Lobe; Excitatory Amino Acid Transporter 2; Female; Glial Fibrillary Acidic Protein; Glutamate-Ammonia Ligase; Glutamic Acid; Hippocampus; Humans; Male; Middle Aged; Neuroglia; Neurons; Sclerosis

2005
Impairment of glutamate transport and increased vulnerability to oxidative stress in neuroblastoma SH-SY5Y cells expressing a Cu,Zn superoxide dismutase typical of familial amyotrophic lateral sclerosis.
    Neurochemistry international, 2005, Volume: 46, Issue:3

    Topics: Amino Acid Transport System X-AG; Amyotrophic Lateral Sclerosis; Antioxidants; Biological Transport, Active; Brain Neoplasms; Cell Line, Tumor; Electrophoresis, Agar Gel; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Kinetics; Mutation; Neuroblastoma; Oxidants; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Superoxide Dismutase; Symporters

2005
Lymphocytic vasculitis mimicking aggressive multifocal cerebral neoplasm: mr imaging and MR spectroscopic appearance.
    AJNR. American journal of neuroradiology, 2005, Volume: 26, Issue:3

    Topics: Adult; Brain; Brain Neoplasms; Choline; Diagnosis, Differential; Female; Glutamic Acid; Glutamine; Humans; Lymphocytes; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Vasculitis, Central Nervous System

2005
[Proton magnetic resonance spectroscopy (1H-MRS) for the diagnosis of brain tumors and the evaluation of treatment].
    Neuro-Chirurgie, 2005, Volume: 51, Issue:3-4 Pt 2

    Topics: Acetates; Alanine; Amino Acids; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Glutamic Acid; Glutamine; Humans; Inositol; Lactates; Magnetic Resonance Spectroscopy; Neoplasm Invasiveness; Oligodendroglioma; Phospholipids; Protons; Time Factors

2005
Simultaneous detection of resolved glutamate, glutamine, and gamma-aminobutyric acid at 4 T.
    Journal of magnetic resonance (San Diego, Calif. : 1997), 2007, Volume: 185, Issue:2

    Topics: Algorithms; Brain; Brain Neoplasms; Complex Mixtures; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Neurotransmitter Agents

2007
Metabolite findings in tumefactive demyelinating lesions utilizing short echo time proton magnetic resonance spectroscopy.
    AJNR. American journal of neuroradiology, 2007, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Demyelinating Diseases; Diagnosis, Differential; Echo-Planar Imaging; Female; Glutamic Acid; Humans; Lactic Acid; Male; Middle Aged; Multiple Sclerosis; Protons

2007
DNA methylation dependent silencing of the human glutamate transporter EAAT2 gene in glial cells.
    Glia, 2007, Volume: 55, Issue:7

    Topics: Animals; Astrocytes; Brain; Brain Chemistry; Brain Neoplasms; Cells, Cultured; CpG Islands; DNA Methylation; Epigenesis, Genetic; Excitatory Amino Acid Transporter 2; Gene Silencing; Genes, Reporter; Glioma; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; HeLa Cells; Humans; Neuroglia; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley

2007
Increase in glutamate as a sensitive indicator of extracellular matrix integrity in peritumoral edema: a 3.0-tesla proton magnetic resonance spectroscopy study.
    Journal of neurosurgery, 2007, Volume: 106, Issue:4

    Topics: Aged; Aged, 80 and over; Brain Edema; Brain Neoplasms; Case-Control Studies; Extracellular Matrix; Female; Glioma; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Meningioma; Middle Aged

2007
Autocrine glutamate signaling promotes glioma cell invasion.
    Cancer research, 2007, Oct-01, Volume: 67, Issue:19

    Topics: Amino Acid Transport System y+; Animals; Brain Neoplasms; Calcium; Cell Line, Tumor; Cell Movement; Female; Glioblastoma; Glutamic Acid; Humans; Mice; Mice, Nude; Neoplasm Invasiveness; Random Allocation; Receptors, AMPA; Signal Transduction; Sulfasalazine

2007
Spectral simplification for resolved glutamate and glutamine measurement using a standard STEAM sequence with optimized timing parameters at 3, 4, 4.7, 7, and 9.4T.
    Magnetic resonance in medicine, 2008, Volume: 59, Issue:2

    Topics: Animals; Brain; Brain Neoplasms; Computer Simulation; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Phantoms, Imaging; Rats; Rats, Sprague-Dawley

2008
Human herpesvirus 6 (HHV-6) induces dysregulation of glutamate uptake and transporter expression in astrocytes.
    Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2008, Volume: 3, Issue:2

    Topics: Astrocytes; Astrocytoma; Brain Neoplasms; Cell Line, Tumor; Cells, Cultured; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Gene Expression Regulation, Viral; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glycoproteins; Herpesvirus 6, Human; Humans; Immediate-Early Proteins; Reverse Transcriptase Polymerase Chain Reaction; Viral Core Proteins; Virus Latency; Virus Replication

2008
Tetramethylpyrazine inhibits activities of glioma cells and glutamate neuro-excitotoxicity: potential therapeutic application for treatment of gliomas.
    Neuro-oncology, 2008, Volume: 10, Issue:2

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Coculture Techniques; Glioma; Glutamic Acid; Microdialysis; Nerve Degeneration; Neurons; Pyrazines; Rats; Rats, Sprague-Dawley; Xenograft Model Antitumor Assays

2008
Drug assessment based on detection of L-glutamate released from C6 glioma cells using an enzyme-luminescence method.
    Analytical chemistry, 2008, May-15, Volume: 80, Issue:10

    Topics: 4-Aminopyridine; Animals; Brain Neoplasms; Carbamazepine; Cell Line, Tumor; Enzymes; Flunarizine; Glioma; Glutamic Acid; Lidocaine; Luminescence; Nickel; Nifedipine; Rats; Veratridine

2008
Imaging of brain tumors after administration of L-(N-13)glutamate: concise communication.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1982, Volume: 23, Issue:8

    Topics: Adolescent; Adult; Blood-Brain Barrier; Brain Neoplasms; Child; Female; Glutamates; Glutamic Acid; Humans; Male; Nitrogen Radioisotopes; Sodium Pertechnetate Tc 99m; Technetium; Tomography, Emission-Computed; Tomography, X-Ray Computed

1982
Effect of cocaine on macromolecular syntheses and cell proliferation in cultured glial cells.
    Neuroscience, 1993, Volume: 57, Issue:2

    Topics: Animals; Animals, Newborn; Brain Neoplasms; Cell Division; Cells, Cultured; Cocaine; DNA; Glioma; Glutamates; Glutamic Acid; L-Lactate Dehydrogenase; Leucine; Nerve Tissue Proteins; Neuroglia; Rats; Rats, Sprague-Dawley; RNA; Thymidine; Trypan Blue; Tumor Cells, Cultured; Uridine

1993
BCL-2 blocks glutamate toxicity in neural cell lines.
    Brain research. Molecular brain research, 1993, Volume: 19, Issue:4

    Topics: Animals; Brain Neoplasms; Cell Line, Transformed; Cell Survival; Cerebellum; CHO Cells; Cricetinae; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Humans; Mice; Neurons; Neurotoxins; PC12 Cells; Potassium Chloride; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogenes; Rats; Transfection

1993
High-resolution 1H-magnetic resonance spectroscopy of pediatric posterior fossa tumors in vitro.
    Journal of neurosurgery, 1994, Volume: 81, Issue:3

    Topics: Adolescent; Alanine; Amino Acids; Animals; Aspartic Acid; Astrocytoma; Brain Neoplasms; Cerebellar Neoplasms; Child; Child, Preschool; Choline; Cranial Fossa, Posterior; Glutamates; Glutamic Acid; Humans; In Vitro Techniques; Infant; Magnetic Resonance Spectroscopy; Medulloblastoma; Neuroectodermal Tumors; Neurotransmitter Agents; Rats; Valine

1994
Proton MR spectroscopy of experimental brain tumors in vivo.
    Acta neurochirurgica. Supplementum, 1994, Volume: 60

    Topics: Animals; Aspartic Acid; Blood Glucose; Brain Edema; Brain Neoplasms; Caudate Nucleus; Cell Line; Choline; Creatinine; Energy Metabolism; Glioma; Glutamic Acid; Inositol; Magnetic Resonance Imaging; Male; Neoplasm Transplantation; Neurilemmoma; Neuroblastoma; Phosphocreatine; Rats; Rats, Inbred F344

1994
Human epileptic astrocytes exhibit increased gap junction coupling.
    Glia, 1995, Volume: 15, Issue:2

    Topics: Astrocytes; Astrocytoma; Brain Neoplasms; Calcium; Cerebral Cortex; Culture Techniques; Electroencephalography; Epilepsy; Gap Junctions; Glutamic Acid; Humans; Magnetic Resonance Imaging; Microscopy, Fluorescence; Temporal Lobe

1995
Characteristic metabolic profiles revealed by 1H NMR spectroscopy for three types of human brain and nervous system tumours.
    NMR in biomedicine, 1995, Volume: 8, Issue:6

    Topics: Alanine; Amino Acids; Brain Neoplasms; Choline; Chromatography, High Pressure Liquid; Creatine; Glioblastoma; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Meningioma; Neuroblastoma; Tumor Cells, Cultured

1995
Reactive oxygen species involved in the glutamate toxicity of C6 glioma cells via xc antiporter system.
    Neuroscience, 1996, Volume: 73, Issue:1

    Topics: Adenosine Triphosphate; Animals; Antiporters; Brain Neoplasms; Cell Death; Cell Nucleus; Cystine; DNA Damage; Free Radical Scavengers; Glioma; Glutamate-Ammonia Ligase; Glutamic Acid; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenases; Lipid Peroxides; Rats; Reactive Oxygen Species; Tumor Cells, Cultured

1996
Effect of 6-aminonicotinamide on metabolism of astrocytes and C6-glioma cells.
    Metabolic brain disease, 1997, Volume: 12, Issue:1

    Topics: 6-Aminonicotinamide; Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Brain Neoplasms; Cells, Cultured; Enzyme Inhibitors; Glioma; Glucose; Glutamic Acid; Lactic Acid; Nerve Tissue Proteins; Phosphocreatine; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured

1997
Characterization of metabotropic glutamate receptors in rat C6 glioma cells.
    European journal of pharmacology, 1997, May-12, Volume: 326, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Membrane; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glioma; Glutamic Acid; Guanylyl Imidodiphosphate; Kinetics; Neuroprotective Agents; Radioligand Assay; Rats; Receptors, Metabotropic Glutamate; Tumor Cells, Cultured

1997
Novel anti-brain tumor cytotoxins specific for cancer cells.
    Nature biotechnology, 1998, Volume: 16, Issue:5

    Topics: Antineoplastic Agents; Brain Neoplasms; Carrier Proteins; Cell Division; Cytotoxins; Exotoxins; Glioma; Glutamic Acid; Humans; Interleukin-13; Interleukin-13 Receptor alpha1 Subunit; Lysine; Mutation; Plasmids; Pseudomonas aeruginosa; Receptors, Cell Surface; Receptors, Interleukin; Receptors, Interleukin-13; Recombinant Fusion Proteins; Tumor Cells, Cultured

1998
Intraoperative microdialysis and tissue-pO2 measurement in human glioma.
    Acta neurochirurgica. Supplement, 1998, Volume: 71

    Topics: Aspartic Acid; Brain Edema; Brain Neoplasms; Cell Death; Female; Frontal Lobe; Glioblastoma; Glutamic Acid; Humans; Male; Microdialysis; Monitoring, Intraoperative; Oxygen Consumption; Prognosis; Temporal Lobe

1998
Lactate turnover in rat glioma measured by in vivo nuclear magnetic resonance spectroscopy.
    Cancer research, 1998, Nov-15, Volume: 58, Issue:22

    Topics: Animals; Brain Neoplasms; Carbon Isotopes; Glioma; Glucose; Glutamic Acid; Glycolysis; Lactic Acid; Magnetic Resonance Spectroscopy; Rats

1998
[1-(13)C]glucose metabolism in the tumoral and nontumoral cerebral tissue of a glioma-bearing rat.
    Journal of neurochemistry, 1999, Volume: 72, Issue:6

    Topics: Alanine; Amino Acids; Analysis of Variance; Animals; Aspartic Acid; Body Weight; Brain; Brain Neoplasms; Carbon Isotopes; Citric Acid Cycle; Female; Functional Laterality; gamma-Aminobutyric Acid; Glioma; Glucose; Glutamic Acid; Glutamine; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Models, Chemical; Nerve Tissue Proteins; Rats; Rats, Wistar; Tumor Cells, Cultured

1999
Characterization of neocortical and hippocampal synaptosomes from temporal lobe epilepsy patients.
    Brain research, 1999, Aug-07, Volume: 837, Issue:1-2

    Topics: Adult; Animals; Brain Neoplasms; Calcium; Epilepsy, Temporal Lobe; Female; gamma-Aminobutyric Acid; GAP-43 Protein; Glial Fibrillary Acidic Protein; Glutamic Acid; Hippocampus; Humans; Male; Membrane Potentials; Neocortex; Nerve Tissue Proteins; Phosphorylation; Potassium; Rats; Synaptosomes

1999
Inhibitory effects of constituents of Gastrodia elata Bl. on glutamate-induced apoptosis in IMR-32 human neuroblastoma cells.
    Archives of pharmacal research, 1999, Volume: 22, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Calcium; Calcium Signaling; Chelating Agents; DNA Fragmentation; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Neuroblastoma; Tumor Cells, Cultured

1999
Compromised glutamate transport in human glioma cells: reduction-mislocalization of sodium-dependent glutamate transporters and enhanced activity of cystine-glutamate exchange.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Dec-15, Volume: 19, Issue:24

    Topics: Amino Acid Substitution; Amino Acid Transport System X-AG; Animals; Astrocytes; ATP-Binding Cassette Transporters; Benzoates; Brain Neoplasms; Cells, Cultured; Cystine; Excitatory Amino Acid Antagonists; Glioma; Glucose Transporter Type 1; Glutamic Acid; Glycine; Humans; Monosaccharide Transport Proteins; Rats; Rats, Sprague-Dawley; Sodium; Tissue Distribution

1999
Extracellular glutamate and other metabolites in and around RG2 rat glioma: an intracerebral microdialysis study.
    Journal of neuro-oncology, 2000, Volume: 47, Issue:1

    Topics: Amino Acids; Animals; Ascorbic Acid; Brain Chemistry; Brain Neoplasms; Extracellular Space; Female; Glioma; Glucose; Glutamic Acid; Lactic Acid; Magnetic Resonance Imaging; Microdialysis; Rats; Rats, Inbred F344; Uric Acid

2000
High glycolytic activity in rat glioma demonstrated in vivo by correlation peak 1H magnetic resonance imaging.
    Cancer research, 2001, Jul-15, Volume: 61, Issue:14

    Topics: Alanine; Animals; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Ethanolamines; Female; Glioma; Glucose; Glutamic Acid; Glutamine; Glycolysis; Lactic Acid; Magnetic Resonance Imaging; Phosphocreatine; Rats; Rats, Sprague-Dawley; Taurine; Tumor Cells, Cultured

2001
Excitotoxic destruction facilitates brain tumor growth.
    Nature medicine, 2001, Volume: 7, Issue:9

    Topics: Animals; Brain Neoplasms; Glioma; Glutamic Acid; Humans; N-Methylaspartate

2001
Glutamate release promotes growth of malignant gliomas.
    Nature medicine, 2001, Volume: 7, Issue:9

    Topics: Amino Acid Transport System X-AG; Animals; Brain Neoplasms; Carrier Proteins; Cell Division; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glioma; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Luminescent Measurements; Male; Memantine; Neoplasm Transplantation; Neurons; Rats; Rats, Inbred F344; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Symporters; Tumor Cells, Cultured

2001
Dysembryoplastic neuroepithelial tumour (DNT). Is the mechanism of seizures related to glutamate? An immunohistochemical study.
    Folia neuropathologica, 2001, Volume: 39, Issue:2

    Topics: Adult; Brain Neoplasms; Glutamic Acid; Humans; Immunohistochemistry; Male; Neoplasms, Neuroepithelial; Seizures; Teratoma

2001
Magnetic resonance spectroscopy and metabolism. Applications of proton and 13C NMR to the study of glutamate metabolism in cultured glial cells and human brain in vivo.
    Biochimie, 1991, Volume: 73, Issue:1

    Topics: Animals; Astrocytes; Brain; Brain Edema; Brain Neoplasms; Cell Line; Glioma; Glutamates; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Neuroglia; Neurotransmitter Agents; Tumor Cells, Cultured

1991
Ionic concentration of shifting fluid during glutamate-induced swelling of cultured glioma cells estimated by the cytocrit technique.
    Advances in neurology, 1990, Volume: 52

    Topics: Animals; Brain Neoplasms; Electrolytes; Glioma; Glutamates; Glutamic Acid; Intracellular Fluid; Osmolar Concentration; Rats; Tumor Cells, Cultured

1990
Aspartame. Review of safety issues. Council on Scientific Affairs.
    JAMA, 1985, Jul-19, Volume: 254, Issue:3

    Topics: Adolescent; Adult; Animals; Aspartame; Aspartic Acid; Brain Chemistry; Brain Diseases; Brain Neoplasms; Carbonated Beverages; Carcinogens; Child; Dietary Carbohydrates; Diketopiperazines; Dipeptides; Drug Stability; Endocrine System Diseases; Female; Glutamates; Glutamic Acid; Humans; Infant; Intellectual Disability; Methanol; Mice; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Piperazines; Pregnancy; Rats

1985
Effect of glutamate analogues on brain tumor cell lines.
    Journal of neurochemistry, 1985, Volume: 45, Issue:4

    Topics: 2-Aminoadipic Acid; Aminobutyrates; Brain Neoplasms; Cell Division; Cell Line; Glioma; Glutamates; Glutamic Acid; Glutamine; Homocysteine; Medulloblastoma; Neuroglia; Sarcoma

1985