glutamic acid has been researched along with Brain Neoplasms in 168 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (1.79) | 18.7374 |
1990's | 20 (11.90) | 18.2507 |
2000's | 42 (25.00) | 29.6817 |
2010's | 79 (47.02) | 24.3611 |
2020's | 24 (14.29) | 2.80 |
Authors | Studies |
---|---|
Akkulak, A; Dağdelen, DN; Diniz, G; Kahraman, DS; Oktay, E; Şenoğlu, M; Yalçın, A; Yalcin, GD | 1 |
Gunn, B; Keniry, M; Litif, C; Lopez, A; Schuenzel, E; Udawant, S | 1 |
Menard, F; Tabatabaee, M | 1 |
Chinnaiyan, P; Cho, K; Dunphy, MP; Frankfater, C; Gass, H; Graham, MS; Grkovski, M; Ippolito, JE; Jones, JK; Krebs, S; Luo, J; Mauguen, A; Nunez, E; Patti, GJ; Rubin, JB; Schaefer, J; Spitz, DR; Sponagel, J; Tinkum, KL; Tung, O; Zhang, S | 1 |
Feyissa, AM; Quiñones-Hinojosa, A; Rosenfeld, SS | 1 |
Conejos-Sánchez, I; Masiá, E; Melnyk, T; Vicent, MJ; Zagorodko, O | 1 |
Ashkan, K; Kumaria, A | 1 |
Jo, S; Kang, H; Kang, J; Kim, B; Kim, HY; Lee, H; Lee, JM; Lee, JS; Park, E; Park, J; Shin, E; Youn, B; Youn, H | 1 |
Galland, F; Gonçalves, CA; Leite, MC; Seady, M; Smaili, SS; Taday, J | 1 |
Campbell, SC; Chaunsali, L; Mills, WA; Muñoz-Ballester, C; Robel, S; Sontheimer, H; Yang, JH | 1 |
Erisnor, G; Khan, A; Lee, KC; Pei, Z; Wang, HY | 1 |
Gillespie, DL; Huang, LE; Jensen, RL; Tiburcio, PDB | 1 |
Bao, L; Chen, Y; DeBerardinis, RJ; Hatanpaa, KJ; Luo, W; Patel, T; Shi, X; Wang, Y; Zhang, B; Zhou, M | 1 |
Asklund, T; Bergenheim, AT; Bergström, P; Björn, E; Johansson, M; Tabatabaei, P | 1 |
Biffoni, M; Buccarelli, M; Ciocca, M; Cirrone, GAP; Dini, V; Grande, S; Guidoni, L; Luciani, AM; Pallini, R; Palma, A; Ricci-Vitiani, L; Rosi, A; Viti, V | 1 |
Batsios, G; Gillespie, AM; Lakhani, A; Molloy, AR; Najac, C; Pieper, RO; Radoul, M; Ronen, SM; Subramani, E; Viswanath, P | 1 |
D'Cruze, L; Ganesh, K; Pacharla, H; Padmavathy, KP; Pitani, R; Prathiba, D; Rayala, SK; Saravanan, R; Venkatraman, G; Venu, A; Vuttaradhi, VK | 1 |
Cseh, O; Luchman, HA; Pugh, TJ; Restall, IJ; Richards, LM; Weiss, S | 1 |
Chen, C; Hu, X; Moni, MA; Peng, S; Quinn, JMW; Rahman, MH; Rana, HK | 1 |
Abe, M; Hirose, Y; Inamasu, J; Kumon, M; Kuwahara, K; Murayama, K; Nakae, S; Ohba, S; Sasaki, H; Yamada, S | 1 |
Akkulak, A; Dagdelen, DN; Donmez Yalcin, G | 1 |
Hörnschemeyer, J; Kirschstein, T; Lange, F | 1 |
Banyas, E; Benbenishty, A; Blinder, P; David, S; Goldshmit, Y; Mayo, L; Perelroizen, R; Ruban, A; Shalom, M; Yakovchuk, A | 1 |
Belcaid, Z; Brem, H; Choi, J; Ehresman, J; Huq, S; Jackson, C; Jackson, CM; Kim, T; Kim, YH; Lim, M; Mathios, D; Medikonda, R; Pant, A; Patel, K; Pennington, Z; Routkevitch, D; Saleh, L; Shah, PP; Srivastava, S; Tong, L; Tyler, B; Xia, Y | 1 |
Catalano, M; Civiero, L; D'Agnano, I; Familiari, G; Familiari, P; Iovino, L; Limatola, C; Monaco, L; Raspa, M; Relucenti, M; Scavizzi, F; Serpe, C | 1 |
Buchfelder, M; Chen, D; Eyupoglu, IY; Fan, Z; Rauh, M; Savaskan, N | 1 |
Bachoo, RM; Baskin, DS; Ijare, OB; Maher, EA; Malloy, CR; Marin-Valencia, I; Mashimo, T; Mickey, BE; Pichumani, K; Vemireddy, V | 1 |
Cudalbu, C; Gruetter, R; Hamou, MF; Hegi, ME; Lai, M; Lanz, B; Poitry-Yamate, C; Vassallo, I | 1 |
Camelo-Piragua, S; Chinnaiyan, A; Koschmann, C; Leung, D; McFadden, K; Mody, R; Pratt, D; Venneti, S | 1 |
Botman, D; de Bitter, T; Heerschap, A; Hendriks, W; Huynen, MA; Khurshed, M; Kusters, B; Leenders, WPJ; Lenting, K; Molenaar, RJ; Peeters, TH; Span, PN; Ter Laan, M; van den Heuvel, CNAM; van Ewijk, A; van Lith, SAM; van Noorden, CJF; Verrijp, K | 1 |
Cerdán, S; García-Martín, ML; Lopez-Larrubia, P; Mucci, A; Righi, V; Schenetti, L; Tugnoli, V | 1 |
Akashi, K; Baba, E; Hirata, Y; Kamenori, S; Mitsuishi, Y; Nagano, O; Okazaki, S; Sampetrean, O; Saya, H; Shintani, S; Suina, K; Takahashi, F; Takahashi, K; Tsuchihashi, K; Yamasaki, J | 1 |
Bergner, C; Hörnschemeyer, J; Kirschstein, T; Köhling, R; Krause, BJ; Lange, F; Linnebacher, M; Mullins, CS; Porath, K; Weßlau, K | 1 |
Davis, KA; Desmond, P; Drummond, K; Glarin, R; Hariharan, H; Kwan, P; Moffat, BA; Morokoff, A; Nanga, RPR; Neal, A; O'Brien, TJ; Reddy, R; Shinohara, RT; Stein, JM | 1 |
Chappé, C; Colin, C; Figarella-Branger, D; Fina, F; Forest, F; Lena, G; Loundou, A; Mercurio, S; Nanni-Metellus, I; Padovani, L; Scavarda, D | 1 |
Batchelor, TT; Borger, DR; Chi, AS; Dias-Santagata, D; Ellisen, LW; Iafrate, AJ; Louis, DN; Yang, D | 1 |
Bachoo, R; Choi, C; Deberardinis, R; Dimitrov, I; Ganji, S; Hulsey, K; Kovacs, Z; Madan, A; Maher, E; Malloy, C; Mendelsohn, D; Mickey, B; Pichumani, K; Zhang, S | 1 |
Amos, A; Bost, J; Maroon, J; Zuccoli, G | 1 |
Blecic, S; De Witte, O; Lefranc, F; Rynkowski, M | 1 |
Robert, SM; Sontheimer, H | 1 |
D'Alonzo, D; Glatz, K | 1 |
Hirato, J; Ikota, H; Kurihara, H; Nagaishi, M; Nakazato, Y; Nobusawa, S; Ogawa, A; Okura, N; Yokoo, H | 1 |
Bjorksten, A; Desmond, PM; Drummond, KJ; Kaye, AH; Liubinas, SV; Moffat, BA; Morokoff, AP; O'Brien, TJ | 1 |
Drummond, KJ; Kaye, AH; Liubinas, SV; Moffat, BM; Morokoff, AP; O'Brien, TJ | 1 |
Bjerkvig, R; Leenders, WP; Molenaar, R; Navis, AC; Niclou, SP; Tops, B; van Lith, SA; van Noorden, CJ; Verrijp, K; Wesseling, P | 1 |
Cai, L; Chaumeil, MM; Eriksson, P; Larson, PE; Lupo, JM; Nelson, SJ; Phillips, JJ; Pieper, RO; Robinson, AE; Ronen, SM; Vigneron, DB; Woods, SM | 1 |
Hayashi, Y; Miyashita, K; Nakada, M; Nobusawa, S; Sabit, H; Suzuki, SO; Tanaka, S | 1 |
Deneka-Hannemann, S; Jarosz, B; Rzeski, W; Stoma, F; Trojanowski, T; Turski, WA; Walczak, K; Zgrajka, W | 1 |
Arvanitis, TN; English, M; Gill, SK; MacPherson, L; Peet, AC; Wilson, M | 1 |
LeBoeuf, NR; Lee, EQ; Ruland, S; Santagata, S; Wen, PY | 1 |
Chen, R; Daemen, A; Deng, Y; Forrest, WF; Friedman, LS; Hatzivassiliou, G; Hedehus, M; Kharbanda, S; Kwong, M; Nishimura, MC; Peale, F; Phillips, HS | 1 |
Chen, J; Gao, H; He, Q; Jiang, X; Qian, J; Ruan, S; Shen, S; Yang, W; Zhu, J | 1 |
McGovern, RA; McKhann, GM; Nelp, TB | 1 |
Amiridis, S; Ching, J; Kaye, AH; Morokoff, AP; O'Brien, TJ; Stylli, SS | 1 |
Bachoo, RM; Barnett, S; DeBerardinis, RJ; Foong, C; Hatanpaa, KJ; Huang, Z; Kovacs, Z; Maher, EA; Mashimo, T; Mickey, BE; Nannepaga, S; Piccirillo, SG; Pichumani, K; Singh, DK; Sirasanagandla, S; Tu, BP; Vemireddy, V | 1 |
Kang, DZ; Lin, RY; Wang, XF; Yao, PS; Ye, ZC | 1 |
Ejima, Y; Gini, B; Hosoda, K; Imahori, T; Irino, Y; Kohmura, E; Kyotani, K; Masui, K; Mischel, PS; Mizowaki, T; Nagashima, H; Sasaki, R; Sasayama, T; Satoh, N; Takata, K; Tanaka, K; Yang, H | 1 |
Amiridis, S; Bjorksten, AR; Ching, J; Kaye, AH; Kountouri, N; Luwor, RB; Morokoff, AP; O'Brien, TJ; Paradiso, L; Stylli, SS; Zheng, T | 1 |
Choi, J; Régnier-Vigouroux, A; Savaskan, NE; Stradmann-Bellinghausen, B; Yakubov, E | 1 |
Wang, K; Zhang, K; Zhou, F; Zhu, L; Zhu, X | 1 |
Hansen, H; Hashizume, Y; Loiacono, KA; Rojas, C; Sahni, V; Sattler, R; Slusher, BS; Tendyke, K; Thomas, AG | 1 |
Boillée, S; Hewett, S; Knackstedt, L; Lewerenz, J; Massie, A | 1 |
Broggini, T; Buchfelder, M; Eyüpoglu, IY; Fan, Z; Savaskan, NE | 1 |
Cheng, M; Eberhart, CG; Fan, X; Glunde, K; Kahlert, UD; Koch, K; Maciaczyk, J; Marchionni, L; Raabe, EH | 1 |
Dembitskaya, Y; Kazantsev, V; Medyanik, I; Mishchenko, M; Tyurikova, O; Vedunova, M; Yashin, K | 1 |
Ahmed, SU; Barnett, SC; Bjerkvig, R; Chalmers, AJ; Fack, F; Gottlieb, E; Hock, AK; Keunen, O; Lindsay, SL; Lund-Johansen, M; Miletic, H; Mørkve, SH; Niclou, SP; Oudin, A; Ruppin, E; Sakariassen, PØ; Tardito, S; Wagner, A; Weinstock, A; Zheng, L | 1 |
Chamberlain, MC | 1 |
Bacher-Stier, C; Berndt, M; Bullich, S; Chin, FT; Dinkelborg, LM; Fels, LM; Friebe, M; Gambhir, SS; Gekeler, V; Hoehne, A; Iagaru, AH; Keu, KV; Koglin, N; Kumar, M; Mittra, ES; Moon, DH; Mosci, C; Mueller, A; Schmitt-Willich, H; Stephens, AW | 1 |
Huberfeld, G; Vecht, CJ | 1 |
Abe, S; Akashi, K; Akiyama, T; Baba, E; Furnari, FB; Ishikawa, M; Iwasaki, Y; Masuko, T; Morikawa, T; Nagane, M; Nagano, O; Ohmura, M; Okazaki, S; Onishi, N; Sampetrean, O; Saya, H; Seishima, R; Shimizu, M; Suematsu, M; Takao, A; Tsuchihashi, K; Wakimoto, H; Yoshikawa, M | 1 |
Hosoda, K; Irino, Y; Itoh, T; Kohmura, E; Kyotani, K; Mizukawa, K; Mukasa, A; Nagashima, H; Sakata, J; Sasaki, R; Sasayama, T; Sato, N; Takeuchi, Y; Tanaka, K; Yamamoto, Y | 1 |
Gottschalk, M; Grand, S; Lamalle, L; Le Bas, JF; Segebarth, C; Troprès, I | 1 |
Bulik, M; Jancalek, R; Kazda, T; Lakomy, R; Pospisil, P; Slampa, P; Smrcka, M | 1 |
D'Orazio, F; Di Cesare, E; Patriarca, L; Splendiani, A | 1 |
Carro, MS; Heiland, DH; Lange, T; Mader, I; Pfeifer, D; Schlosser, P; Schwarzwald, R; Urbach, H; Vasilikos, I; Weyerbrock, A | 1 |
Gilberto González, R; Ratai, EM | 1 |
Ceccanti, M; Chassidim, Y; Colonnese, C; D'Elia, A; Fassler, M; Friedman, A; Inghilleri, M; Nucciarelli, V; Onesti, E; Pell, GS; Prager, O; Raccah, R; Roth, Y; Salvati, M; Santoro, A; Shahar, H; Vazana, U; Veksler, R; Zangen, A | 1 |
MacKenzie, G; Maguire, J; Moss, SJ; O'Toole, KK | 1 |
Bastian, BC; Bollen, AW; Chen, K; Gong, H; Jin, LW; Joseph, NM; Nicolaides, T; Perry, A; Phillips, JJ; Shieh, JT; Solomon, DA; van Ziffle, J | 1 |
Bergenheim, AT; Bergström, P; Brännström, T; Siesjö, P; Tabatabaei, P; Visse, E | 1 |
Maus, A; Peters, GJ | 1 |
Albrecht, J; Szeliga, M | 1 |
Ding, MP; Ding, Y; Guo, Y; Shen, CH; Tang, YL; Wang, S; Zhang, YX; Zheng, Y; Zhu, JM | 1 |
Aizenstein, O; Artzi, M; Ben Bashat, D; Bokstein, F; Liberman, G; Vaisman, N; Vitinshtein, F | 1 |
Koster, J; Lasky, JL; Lin, HJ; Panosyan, EH | 1 |
Bergenheim, AT; Bergström, P; Henriksson, R; Tabatabaei, P | 1 |
Simpkins, JW; Yi, KD | 1 |
Bjerkvig, R; Enger, PØ; Hajek, M; Jirak, D; Sykova, E; Thorsen, F; van der Kogel, A; Wang, J | 1 |
Bergenheim, AT; Lindvall, P; Roslin, M | 1 |
Fan, GG; Guo, QY; Sun, HZ; Wang, GL | 1 |
Aronica, E; Boer, K; Gorter, JA; Jansen, F; Nellist, M; Spliet, WG; Timmermans, W; Troost, D | 1 |
Avdievich, NI; Baehring, JM; Hetherington, HP; Pan, JW; Spencer, DD | 1 |
Hou, BL; Hu, J | 1 |
Eyüpoglu, IY; Hahnen, E; Savaskan, NE | 1 |
Aronica, E; Bosma, I; Broekhuizen, AJ; Cloos, J; Heimans, JJ; Kaspers, GJ; Postma, TJ; Tannous, BA; van der Valk, P; van Vuurden, DG; Würdinger, T; Yazdani, M | 1 |
Darra, E; Ebner, FH; Mariotto, S; Shoji, K; Suzuki, H | 1 |
Eyüpoglu, IY; Hahnen, E; Hauke, J; Savaskan, NE; Seufert, S; Tränkle, C | 1 |
Ackermann, H; Blasel, S; Franz, K; Hattingen, E; Weidauer, S; Zanella, F | 1 |
Liu, SC; Wang, YY; Yang, Z; Zhang, T | 1 |
de Groot, J; Sontheimer, H | 1 |
Eloqayli, H; Haukvik, A; Melø, TM; Sonnewald, U | 1 |
Choi, JK; Das, SK; Dash, R; Emdad, L; Fisher, PB; Howlett, EL; Jeon, HY; Kang, DC; Kegelman, TP; Kim, K; Kim, SH; Lee, SG; Sarkar, D; Su, ZZ; Yoo, BK | 1 |
Buckingham, SC; Campbell, SL; Haas, BR; Montana, V; Ogunrinu, T; Robel, S; Sontheimer, H | 1 |
Simon, M; von Lehe, M | 1 |
Berghoff, AS; Birner, P; Capper, D; Habel, A; Hackl, M; Ilhan, A; Magerle, M; Meyer, J; Petzelbauer, P; Pichler, J; Preusser, M; Pusch, S; von Deimling, A; Wöhrer, A | 1 |
Sontheimer, H | 3 |
Cai, K; Detre, JA; Greenberg, JH; Hariharan, H; Haris, M; Kogan, F; Reddy, R; Singh, A | 1 |
Galeffi, F; Turner, DA | 1 |
Bachoo, RM; Cho, SK; Choi, C; Deberardinis, RJ; Good, LB; Hatanpaa, KJ; Jindal, A; Kapur, P; Maher, EA; Malloy, CR; Marin-Valencia, I; Mashimo, T; Mickey, B; Pascual, JM; Raisanen, J; Rakheja, D; Sun, X; Takahashi, M; Togao, O; Vemireddy, V | 1 |
Berkutzki, T; Cooper, I; Mohar, B; Ruban, A; Teichberg, VI | 1 |
Bachoo, RM; Baek, H; Cai, L; Cho, S; Deberardinis, RJ; Good, L; Hatanpaa, KJ; Maddie, M; Maher, EA; Malloy, CR; Marin-Valencia, I; Mashimo, T; Matés, JM; Mickey, BE; Pascual, JM; Rajagopalan, KN; Tu, BP; Vemireddy, V; Yang, C; Yang, XL; Zhao, Z | 1 |
Buckingham, SC; Campbell, SL; Sontheimer, H | 1 |
Bode, J; Caballero, B; Gaitner, M; Gavish, M; Kietz, S; Kugler, W; Lakomek, M; Peʼer, Y; Veenman, L; Zeno, S | 1 |
Barzó, P; Komlósi, G; Molnár, G; Oláh, S; Rózsa, M; Tamás, G | 1 |
Celio, MR; D'Orlando, C; Schwaller, B | 1 |
Rothstein, JD | 1 |
Acebes, JJ; Aguilera, C; Alonso, J; Arús, C; Gili, J; Majós, C; Serrallonga, M | 1 |
Bernsen, H; Boerman, R; Heerschap, A; Rijpkema, M; Schuuring, J; van der Graaf, M; van der Kogel, A; van der Meulen, Y | 1 |
Dezortová, M; Hájek, M; Liscák, R; Vladyka, V; Vymazal, J | 1 |
Buydens, LM; Heerschap, A; Melssen, WJ; Postma, GJ; Simonetti, AW; van der Graaf, M | 1 |
Blanco, I; Dot, J; Lluch, M; Rodríguez-Alvarez, J | 1 |
Sutherland, ML; Zhou, J | 1 |
Brennan, L; Hewage, C; Malthouse, JP; McBean, GJ | 1 |
McKnight, TR | 1 |
Bos, IW; de Graan, PN; Notenboom, RG; van der Hel, WS; van Rijen, PC; van Veelen, CW | 1 |
Beretta, S; Carrì, MT; Ceresa, C; Ferrarese, C; Ferri, A; Mattavelli, L; Sala, G; Tremolizzo, L; Zoia, C | 1 |
Imbesi, SG; Niku, S; Panchal, NJ | 1 |
Grand, S; Hoffmann, D; Le Bas, JF; Tropres, I; Ziegler, A | 1 |
Bergenheim, AT; Henriksson, R; Ronquist, G; Roslin, M; Ungerstedt, U; Waldenström, A | 1 |
Haacke, EM; Hu, J; Jiang, Q; Xuan, Y; Yang, S; Yang, Y | 1 |
Cianfoni, A; Imbesi, SG; Niku, S | 1 |
Allritz, C; Engele, J; Rein, T; Zschocke, J | 1 |
Igarashi, H; Kimura, T; Kwee, IL; Nakada, T; Ohkubo, M | 1 |
Chung, WJ; Lyons, SA; Ogunrinu, T; Sontheimer, H; Weaver, AK | 1 |
Hu, J; Kou, Z; Yang, S; Yang, Y | 1 |
Akhyani, N; Fotheringham, J; Jacobson, S; Williams, EL | 1 |
Cheng, FC; Cheng, H; Chou, SC; Fu, YS; Fu, YY; Hsu, SY; Kao, LS; Lin, YY; Shih, YH; Tsai, TH; Wang, JY | 1 |
Kitano, H; Shinohara, H; Zakir Hossain, SM | 1 |
Allen, JC; Benua, RS; Gelbard, AS; Laughlin, JS; Reiman, RE; Vomero, JJ | 1 |
Bansinath, M; Garg, UC; Turndorf, H | 1 |
Bredesen, DE; Kane, DJ; Zhong, LT | 1 |
Bonner, K; Gennarelli, L; Rorke, LB; Sutton, LN; Wang, Z; Wehrli, SL; Zimmerman, R | 1 |
Els, T; Gyngell, ML; Hoehn-Berlage, M; Hossmann, KA | 1 |
Cornell-Bell, AH; Lee, SH; Magge, S; Sontheimer, H; Spencer, DD | 1 |
Bhakoo, KK; Florian, CL; Noble, M; Preece, NE; Williams, SR | 1 |
Kato, S; Mawatari, K; Sugitani, K; Takadera, T; Yasui, Y | 1 |
Haghighat, N; McCandless, DW | 1 |
Albasanz, JL; Martín, M; Ros, M | 1 |
Debinski, W; Gibo, DM; Kealiher, A; Obiri, NI; Puri, RK | 1 |
Baunach, S; Gerlach, M; Lan, J; Meixensberger, J; Roosen, K | 1 |
DelaBarre, L; Garwood, M; Gruetter, R; High, WB; Merkle, H; Mescher, M; Terpstra, M | 1 |
Li, SJ; Prost, R; Rand, SD | 1 |
Bouzier, AK; Canioni, P; Merle, M; Quesson, B; Valeins, H | 1 |
Blomenröhr, M; de Graan, PN; de Wit, M; Dijstelbloem, H; Gispen, WH; Hoogland, G; Spierenburg, HA; van Huffelen, AC; van Rijen, PC; van Veelen, CW | 1 |
Ha, JH; Huh, K; Jung, MW; Kang, YS; Kim, JA; Lee, DU; Lee, SH; Lee, YS; Yong, CS | 1 |
Rothstein, JD; Sontheimer, H; Ye, ZC | 1 |
Behrens, PF; Draeger, J; Hennig, J; Langemann, H; Strohschein, R | 1 |
Décorps, M; Rémy, C; von Kienlin , M; Ziegler, A | 1 |
Brem, H; Rothstein, JD | 1 |
Arcuino, G; Gao, Q; Lin, JH; Nedergaard, M; Takano, T; Yang, J | 1 |
Adamek, D; Danilewicz, B; Jeleńska-Szyguła, I; Korzeniowska, A; Lopatka, P; Morga, R | 1 |
Baethmann, A; Kempski, O; Schneider, GH; Staub, F; Weigt, H | 1 |
Allard, M; Biran, M; Caille, JM; Canioni, P; Kien, P; Labouesse, J; Merle, M; Pianet, I; Portais, JC; Raffard, G | 1 |
Gotoh, F; Shinohara, T; Tomita, M | 1 |
Bartel, R; Bigner, DD; Campbell, GL; Freidman, HS | 1 |
24 review(s) available for glutamic acid and Brain Neoplasms
Article | Year |
---|---|
Glutamate Signaling and Filopodiagenesis of Astrocytoma Cells in Brain Cancers: Survey and Questions.
Topics: Astrocytes; Astrocytoma; Brain Neoplasms; Glutamic Acid; Humans; Signal Transduction | 2022 |
Altered glutamatergic and inflammatory pathways promote glioblastoma growth, invasion, and seizures: An overview.
Topics: Brain Neoplasms; Glioblastoma; Glioma; Glutamic Acid; Humans; Seizures; Tumor Microenvironment | 2022 |
Pathway analysis of glutamate-mediated, calcium-related signaling in glioma progression.
Topics: Animals; Brain Neoplasms; Calcium; Disease Progression; Glioblastoma; Glutamic Acid; Humans; Neurons; Nitric Oxide; Signal Transduction | 2020 |
Glutamatergic Mechanisms in Glioblastoma and Tumor-Associated Epilepsy.
Topics: Animals; Anticonvulsants; Antineoplastic Agents; Brain; Brain Neoplasms; Brain Waves; Disease Progression; Epilepsy; Excitatory Amino Acid Antagonists; Glioblastoma; Glutamic Acid; Humans; Receptors, Ionotropic Glutamate; Receptors, Metabotropic Glutamate; Signal Transduction | 2021 |
Restricted calorie ketogenic diet for the treatment of glioblastoma multiforme.
Topics: Animals; Brain Neoplasms; Caloric Restriction; Combined Modality Therapy; Diet, Ketogenic; Glioblastoma; Glucose; Glutamic Acid; Humans; United States | 2013 |
[Glutamate and malignant gliomas, from epilepsia to biological aggressiveness: therapeutic implications].
Topics: Benzodiazepines; Brain Neoplasms; Cell Death; Cell Movement; Cell Proliferation; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glioma; Glutamic Acid; Humans; Memantine; Neoplasm Invasiveness; Neuroglia; Neurons; Receptors, AMPA; Receptors, Glutamate; Seizures; Sulfasalazine | 2013 |
Glutamate transporters in the biology of malignant gliomas.
Topics: Amino Acid Transport System X-AG; Brain Neoplasms; Glioma; Glutamic Acid; Glutathione; Humans; Receptors, Glutamate | 2014 |
Tumour associated epilepsy and glutamate excitotoxicity in patients with gliomas.
Topics: Animals; Brain Neoplasms; Epilepsy; Glioma; Glutamic Acid; Humans; Quality of Life; Synaptic Transmission | 2014 |
Glutamate as chemotactic fuel for diffuse glioma cells: are they glutamate suckers?
Topics: Animals; Brain Neoplasms; Cell Transformation, Neoplastic; Chemotaxis; Enzyme Inhibitors; Glioma; Glutamic Acid; Glutamine; Humans; Isocitrate Dehydrogenase | 2014 |
A novel treatment strategy for glioblastoma multiforme and glioma associated seizures: increasing glutamate uptake with PPARγ agonists.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Excitatory Amino Acid Transporter 2; Glioblastoma; Glutamic Acid; Humans; PPAR gamma; Seizures | 2015 |
Main path and byways: non-vesicular glutamate release by system xc(-) as an important modifier of glutamatergic neurotransmission.
Topics: Animals; Brain; Brain Neoplasms; Glioblastoma; Glutamic Acid; Humans; Oxidative Stress; Synaptic Transmission | 2015 |
Perspectives in Intraoperative Diagnostics of Human Gliomas.
Topics: Brain Neoplasms; Cell Movement; Computational Biology; Glioma; Glutamic Acid; Humans; Image-Guided Biopsy; Intraoperative Period; Magnetic Resonance Imaging; Optical Imaging; Surgery, Computer-Assisted; Ultrasonography | 2015 |
Seizures and gliomas--towards a single therapeutic approach.
Topics: Animals; Anticonvulsants; Brain Neoplasms; GABAergic Neurons; Glioma; Glutamic Acid; Humans; Seizures; Signal Transduction; TOR Serine-Threonine Kinases | 2016 |
Vanishing pineal mass in a young patient without therapy: Case report and review of the literature.
Topics: Adolescent; Aspartic Acid; Brain Neoplasms; Choline; Electroencephalography; Female; Glutamic Acid; Glutamine; Headache; Humans; Hydrocephalus; Magnetic Resonance Imaging; Pineal Gland; Pinealoma; Recovery of Function; Tomography, X-Ray Computed | 2016 |
Clinical magnetic resonance spectroscopy of the central nervous system.
Topics: Aspartic Acid; Brain Chemistry; Brain Neoplasms; Central Nervous System; Choline; Creatine; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy | 2016 |
Glutamate and α-ketoglutarate: key players in glioma metabolism.
Topics: Antimetabolites, Antineoplastic; Brain Neoplasms; Citric Acid Cycle; Gene Expression; Glioblastoma; Glutamic Acid; Humans; Isocitrate Dehydrogenase; Ketoglutaric Acids; Mutation; Neoplasm Grading; Reactive Oxygen Species | 2017 |
[Progress in the study of the chemical synapse in glioma-associated epileptogenesis].
Topics: Brain Neoplasms; Epilepsy; Glioma; Glutamic Acid; Humans; Neurotransmitter Agents; Neurotransmitter Transport Proteins; Synapses | 2008 |
Glutamate and the biology of gliomas.
Topics: Animals; Benzodiazepines; Brain; Brain Neoplasms; Glioma; Glutamic Acid; Humans; Models, Biological; Receptors, AMPA; Signal Transduction | 2011 |
Exploiting metabolic differences in glioma therapy.
Topics: Brain Neoplasms; Glioma; Glutamic Acid; Glutamine; Humans; Hypoxia-Inducible Factor 1; NAD; NADP; Signal Transduction | 2012 |
Ion channels and amino acid transporters support the growth and invasion of primary brain tumors.
Topics: Amino Acid Transport Systems; Animals; Brain Neoplasms; Cell Division; Glioma; Glutamic Acid; Humans; Ion Channels; Neoplasm Invasiveness | 2004 |
Proton magnetic resonance spectroscopic evaluation of brain tumor metabolism.
Topics: Alanine; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Lipid Metabolism; Magnetic Resonance Spectroscopy; Phosphocreatine | 2004 |
A role for glutamate in growth and invasion of primary brain tumors.
Topics: Amino Acid Transport System X-AG; Animals; Antineoplastic Agents; Brain Neoplasms; Cystine; Glioma; Glutamic Acid; Humans; Neoplasm Invasiveness | 2008 |
Proton MR spectroscopy of the brain.
Topics: Brain; Brain Abscess; Brain Diseases; Brain Neoplasms; Carbon Isotopes; Cerebral Infarction; Demyelinating Diseases; Diagnosis, Differential; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Membrane Lipids; Multiple Sclerosis; Neurotransmitter Agents; Phosphorus Isotopes; Protons; United States; United States Food and Drug Administration | 1999 |
Swelling of C6 glioma cells and astrocytes from glutamate, high K+ concentrations or acidosis.
Topics: Acidosis, Lactic; Animals; Astrocytes; Brain Neoplasms; Cell Hypoxia; Cell Size; Glioma; Glutamates; Glutamic Acid; Iodoacetates; Iodoacetic Acid; Ouabain; Potassium; Rats; Sodium-Potassium-Exchanging ATPase; Tumor Cells, Cultured | 1992 |
2 trial(s) available for glutamic acid and Brain Neoplasms
Article | Year |
---|---|
Characterization of oligodendrogliomas using short echo time 1H MR spectroscopic imaging.
Topics: Adult; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Dipeptides; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Oligodendroglioma; Reproducibility of Results; Sensitivity and Specificity | 2003 |
Metabolic manipulation of glioblastoma in vivo by retrograde microdialysis of L-2, 4 diaminobutyric acid (DAB).
Topics: Aged; Aminobutyrates; Antimetabolites, Antineoplastic; Brain Neoplasms; Catheters, Indwelling; Dose-Response Relationship, Drug; Female; Glioblastoma; Glutamic Acid; Glycerol; Humans; Infusions, Intralesional; Male; Microdialysis; Middle Aged; Monitoring, Ambulatory; Stereotaxic Techniques; Taurine; Treatment Outcome | 2006 |
142 other study(ies) available for glutamic acid and Brain Neoplasms
Article | Year |
---|---|
The expression of glutamate metabolism modulators in the intracranial tumors and glioblastoma cell line.
Topics: Adolescent; Adult; Aged; Astrocytes; Brain Neoplasms; Cell Line; Child; Child, Preschool; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Glioblastoma; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamic Acid; Humans; Male; Middle Aged; Mitochondrial Proteins; Neuroglia; Retrospective Studies; Sirtuins | 2022 |
PI3K Pathway Inhibition with NVP-BEZ235 Hinders Glycolytic Metabolism in Glioblastoma Multiforme Cells.
Topics: Brain Neoplasms; Cell Line, Tumor; Forkhead Box Protein O1; Gene Expression Regulation, Neoplastic; Gene Ontology; Glioblastoma; Glucose; Glutamic Acid; Glycolysis; Humans; Imidazoles; Kaplan-Meier Estimate; Lactic Acid; NAD; Phosphatidylinositol 3-Kinases; Prognosis; Protein Kinase Inhibitors; Quinolines; Signal Transduction | 2021 |
Sex differences in brain tumor glutamine metabolism reveal sex-specific vulnerabilities to treatment.
Topics: Animals; Brain Neoplasms; Citric Acid Cycle; Female; Glioma; Glutamic Acid; Glutamine; Humans; Male; Mice; Pyruvate Carboxylase; Sex Characteristics | 2022 |
Rational design of poly-L-glutamic acid-palbociclib conjugates for pediatric glioma treatment.
Topics: Brain Neoplasms; Child; Diffuse Intrinsic Pontine Glioma; Glioma; Glutamic Acid; Humans | 2023 |
Novel therapeutic strategies in glioma targeting glutamatergic neurotransmission.
Topics: Anticonvulsants; Brain Neoplasms; Glioblastoma; Glioma; Glutamic Acid; Humans; Synaptic Transmission | 2023 |
Mitochondrial glutamate transporter SLC25A22 uni-directionally export glutamate for metabolic rewiring in radioresistant glioblastoma.
Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glutamic Acid; Humans; Mitochondria; Mitochondrial Membrane Transport Proteins; Proline; Radiation Tolerance | 2023 |
Astrocyte culture models: Molecular and function characterization of primary culture, immortalized astrocytes and C6 glioma cells.
Topics: Animals; Astrocytes; Brain Neoplasms; Cell Communication; Cell Line; Cell Proliferation; Glial Fibrillary Acidic Protein; Glioma; Glucose; Glutamic Acid; Glutathione; Immunohistochemistry; Male; Primary Cell Culture; Rats; Rats, Wistar; S100 Calcium Binding Protein beta Subunit | 2019 |
Potassium and glutamate transport is impaired in scar-forming tumor-associated astrocytes.
Topics: Animals; Astrocytes; Biological Transport; Brain Neoplasms; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glioma; Glutamic Acid; Mice; Neuroglia; Neurons; Potassium | 2020 |
Extracellular glutamate and IDH1
Topics: Animals; Benzeneacetamides; Brain Neoplasms; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Glioma; Glutamate Dehydrogenase; Glutamic Acid; Humans; Imidazoles; Isocitrate Dehydrogenase; Male; Mice; Oxidation-Reduction; Tumor Cells, Cultured | 2020 |
Regulation of branched-chain amino acid metabolism by hypoxia-inducible factor in glioblastoma.
Topics: Amino Acids, Branched-Chain; Basic Helix-Loop-Helix Transcription Factors; Brain Neoplasms; Cell Hypoxia; Cell Proliferation; Cells, Cultured; CRISPR-Cas Systems; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Glioblastoma; Glutamic Acid; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Large Neutral Amino Acid-Transporter 1; Protein Binding; Transaminases | 2021 |
Intratumoral retrograde microdialysis treatment of high-grade glioma with cisplatin.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain; Brain Neoplasms; Cisplatin; Female; Glioma; Glucose; Glutamic Acid; Glycerol; Humans; Male; Microdialysis; Middle Aged; Neoplasm Recurrence, Local; Quality of Life; Treatment Outcome | 2020 |
Different Mechanisms Underlie the Metabolic Response of GBM Stem-Like Cells to Ionizing Radiation: Biological and MRS Studies on Effects of Photons and Carbon Ions.
Topics: Brain Neoplasms; Cell Line, Tumor; G2 Phase Cell Cycle Checkpoints; gamma-Aminobutyric Acid; Glioblastoma; Glucose; Glutamic Acid; Humans; Ions; Lactic Acid; Magnetic Resonance Spectroscopy; Neoplastic Stem Cells; Phosphocreatine; Photons; Radiation, Ionizing | 2020 |
MR-detectable metabolic biomarkers of response to mutant IDH inhibition in low-grade glioma.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Brain Neoplasms; Carbon-13 Magnetic Resonance Spectroscopy; Cell Line, Tumor; Diamines; Glioma; Glutamic Acid; Glutarates; Glycine; Humans; Isocitrate Dehydrogenase; Mutation; Proton Magnetic Resonance Spectroscopy; Pyridines | 2020 |
Clinical Evaluation of Proline, Glutamic acid, and Leucine-Rich Protein 1 Expression in Astrocytomas and Correlations with the Proliferation Marker Ki-67.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Astrocytoma; Brain Neoplasms; Co-Repressor Proteins; Female; Glutamic Acid; Humans; Ki-67 Antigen; Male; Middle Aged; Neoplasm Grading; Proline; Transcription Factors | 2021 |
Brain Tumor Stem Cell Dependence on Glutaminase Reveals a Metabolic Vulnerability through the Amino Acid Deprivation Response Pathway.
Topics: Amino Acids; Astrocytes; Benzeneacetamides; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Citric Acid Cycle; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glioblastoma; Glutamic Acid; Glutaminase; Humans; Neoplastic Stem Cells; Signal Transduction; Thiadiazoles | 2020 |
Bioinformatics and machine learning methodologies to identify the effects of central nervous system disorders on glioblastoma progression.
Topics: Atlases as Topic; Brain Neoplasms; Central Nervous System; Computational Biology; Datasets as Topic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Ontology; Gene Regulatory Networks; Glioblastoma; Glutamic Acid; Humans; Kaplan-Meier Estimate; Machine Learning; Molecular Sequence Annotation; Neoplasm Proteins; Proportional Hazards Models; Signal Transduction | 2021 |
Association of preoperative seizures with tumor metabolites quantified by magnetic resonance spectroscopy in gliomas.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytes; Brain Neoplasms; Female; Glioma; Glutamic Acid; Humans; Isocitrate Dehydrogenase; Magnetic Resonance Spectroscopy; Male; Metabolome; Middle Aged; Multivariate Analysis; Mutation; Oligodendroglia; Seizures; Survival Analysis; Young Adult | 2021 |
The investigation of glutamate transporter 1 (GLT-1) degradation pathway in glioblastoma cells.
Topics: Brain Neoplasms; Cell Line, Tumor; Excitatory Amino Acid Transporter 2; Glioblastoma; Glutamic Acid; Humans; Proteolysis; Ubiquitin | 2021 |
Blood glutamate scavengers increase pro-apoptotic signaling and reduce metastatic melanoma growth in-vivo.
Topics: Animals; Apoptosis; Aspartate Aminotransferase, Cytoplasmic; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Therapy, Combination; Glioblastoma; Glutamic Acid; Humans; Melanoma; Mice; Mice, Inbred C57BL; Molecular Targeted Therapy; Oxaloacetic Acid; Recombinant Proteins; Signal Transduction; Tumor Microenvironment | 2021 |
Synergy between glutamate modulation and anti-programmed cell death protein 1 immunotherapy for glioblastoma.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glutamic Acid; Immunotherapy; Mice; Mice, Inbred C57BL; Tumor Microenvironment | 2022 |
Microglia-Derived Small Extracellular Vesicles Reduce Glioma Growth by Modifying Tumor Cell Metabolism and Enhancing Glutamate Clearance through miR-124.
Topics: Animals; Antagomirs; Brain Neoplasms; Cell Proliferation; Cells, Cultured; Excitatory Amino Acid Transporter 2; Extracellular Vesicles; Glioma; Glutamic Acid; Interferon-gamma; Kaplan-Meier Estimate; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; MicroRNAs; Nitric Oxide; Up-Regulation | 2021 |
ATF4 promotes angiogenesis and neuronal cell death and confers ferroptosis in a xCT-dependent manner.
Topics: Activating Transcription Factor 4; Amino Acid Transport System y+; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glioma; Glutamic Acid; Humans; Iron; Neovascularization, Pathologic; Neurons | 2017 |
Measurement of
Topics: Acetates; Brain Neoplasms; Carbon Isotopes; Female; Glutamic Acid; Glutamine; Humans; Male | 2017 |
In vivo characterization of brain metabolism by
Topics: Adaptor Proteins, Signal Transducing; Animals; Aspartic Acid; Brain; Brain Neoplasms; Cell Line, Tumor; Fluorodeoxyglucose F18; gamma-Aminobutyric Acid; Glioma; Glucose; Glutamic Acid; Humans; Male; Mice; Neoplasm Transplantation; Oxidation-Reduction; Positron-Emission Tomography; Proton Magnetic Resonance Spectroscopy; Repressor Proteins | 2018 |
BRAF activating mutations involving the β3-αC loop in V600E-negative anaplastic pleomorphic xanthoastrocytoma.
Topics: Astrocytoma; Brain Neoplasms; Child, Preschool; Glutamic Acid; Humans; Male; Mutation; Proto-Oncogene Proteins B-raf; Valine; Young Adult | 2018 |
Isocitrate dehydrogenase 1-mutated human gliomas depend on lactate and glutamate to alleviate metabolic stress.
Topics: 4-Aminobutyrate Transaminase; Animals; Brain Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Glutamate Dehydrogenase; Glutamic Acid; Glutaminase; Humans; Isocitrate Dehydrogenase; Lactic Acid; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Neoplasm Invasiveness; Stress, Physiological; Succinate-Semialdehyde Dehydrogenase; Transcriptome; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2019 |
Spatially Resolved Bioenergetic and Genetic Reprogramming Through the Brain of Rats Bearing Implanted C6 Gliomas As Detected by Multinuclear High-Resolution Magic Angle Spinning and Genomic Analysis.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Biopsy; Brain Neoplasms; Carbon Isotopes; Caudate Nucleus; Cellular Reprogramming; Female; Gene Expression Profiling; Gene Expression Regulation; Glioma; Glucose; Glutamic Acid; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lactic Acid; Magnetic Resonance Imaging; Neoplasm Transplantation; Oxidative Phosphorylation; Rats; Rats, Wistar; Transcription Factors; Transplantation, Heterologous | 2018 |
Epidermal growth factor receptor promotes glioma progression by regulating xCT and GluN2B-containing N-methyl-d-aspartate-sensitive glutamate receptor signaling.
Topics: Amino Acid Transport System y+; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Disease Progression; Dizocilpine Maleate; Drug Synergism; Epidermal Growth Factor; ErbB Receptors; Glioma; Glutamic Acid; Humans; Mice; Neoplasm Transplantation; Phosphorylation; Protein Domains; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sulfasalazine | 2018 |
AMPA receptor antagonist perampanel affects glioblastoma cell growth and glutamate release in vitro.
Topics: Anticonvulsants; Antineoplastic Agents; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Epilepsy; Glioblastoma; Glutamic Acid; Humans; Nitriles; Pyridones; Receptors, AMPA; Seizures; Up-Regulation; Valproic Acid | 2019 |
Glutamate weighted imaging contrast in gliomas with 7 Tesla magnetic resonance imaging.
Topics: Adult; Brain Neoplasms; Epilepsy; Female; Glioma; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged | 2019 |
Dysembryoplastic neuroepithelial tumors share with pleomorphic xanthoastrocytomas and gangliogliomas BRAF(V600E) mutation and expression.
Topics: Adolescent; Antigens, CD34; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; Female; Ganglioglioma; Glutamic Acid; Humans; Infant; Male; Neoplasms, Neuroepithelial; Proto-Oncogene Proteins B-raf; Valine; Young Adult | 2013 |
BRAF V600E mutation identifies a subset of low-grade diffusely infiltrating gliomas in adults.
Topics: Adult; Astrocytoma; Brain Neoplasms; Female; Glioma; Glutamic Acid; Humans; Immunohistochemistry; Male; Neoplasm Grading; Point Mutation; Proto-Oncogene Proteins B-raf; Valine | 2013 |
A comparative study of short- and long-TE ¹H MRS at 3 T for in vivo detection of 2-hydroxyglutarate in brain tumors.
Topics: Adult; Aspartic Acid; Brain Neoplasms; gamma-Aminobutyric Acid; Glioma; Glutamic Acid; Glutamine; Glutarates; Humans; Isocitrate Dehydrogenase; Magnetic Resonance Spectroscopy; Middle Aged; Mutation; Phantoms, Imaging; Protons; Young Adult | 2013 |
Absent response of intracranial melanoma metastases harboring BRAF V600E sequence variation to vemurafenib.
Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Fatal Outcome; Glutamic Acid; Humans; Ileal Neoplasms; Immunohistochemistry; Indoles; Magnetic Resonance Imaging; Male; Melanoma; Proto-Oncogene Proteins B-raf; Skin Neoplasms; Sulfonamides; Treatment Failure; Valine; Vemurafenib | 2013 |
Intratumoral heterogeneity of genomic imbalance in a case of epithelioid glioblastoma with BRAF V600E mutation.
Topics: Brain Neoplasms; DNA Mutational Analysis; Glioblastoma; Glutamic Acid; Humans; Isocitrate Dehydrogenase; Male; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins B-raf; Valine; Young Adult | 2014 |
Glutamate quantification in patients with supratentorial gliomas using chemical shift imaging.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Demography; Female; Glioma; Glutamic Acid; Humans; Linear Models; Magnetic Resonance Imaging; Male; Middle Aged; Phantoms, Imaging; Supratentorial Neoplasms; Young Adult | 2014 |
Hyperpolarized [1-13C] glutamate: a metabolic imaging biomarker of IDH1 mutational status in glioma.
Topics: Animals; Biomarkers, Tumor; Brain Neoplasms; Carbon-13 Magnetic Resonance Spectroscopy; Cell Line, Tumor; Glioma; Glutamic Acid; Humans; Isocitrate Dehydrogenase; Ketoglutaric Acids; Male; Mutation; Radiopharmaceuticals; Rats; Rats, Nude; Transaminases | 2014 |
Epithelioid glioblastoma arising from pleomorphic xanthoastrocytoma with the BRAF V600E mutation.
Topics: Amino Acid Substitution; Astrocytoma; Brain Neoplasms; Child; Female; Glioblastoma; Glutamic Acid; Humans; Magnetic Resonance Imaging; Mutation; Neoplasms, Second Primary; Proto-Oncogene Proteins B-raf; Time Factors; Valine | 2014 |
Kynurenic acid inhibits proliferation and migration of human glioblastoma T98G cells.
Topics: Adult; Aged; Benzodiazepines; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Glioblastoma; Glutamic Acid; Humans; Kynurenic Acid; Male; Middle Aged | 2014 |
Noninvasive detection of glutamate predicts survival in pediatric medulloblastoma.
Topics: Adolescent; Biomarkers, Tumor; Brain Neoplasms; Child; Child, Preschool; Female; Glutamic Acid; Humans; Kaplan-Meier Estimate; Magnetic Resonance Spectroscopy; Male; Medulloblastoma; Precision Medicine; Prognosis; Radiography | 2014 |
Successful Treatment of a Progressive BRAF V600E-Mutated Anaplastic Pleomorphic Xanthoastrocytoma With Vemurafenib Monotherapy.
Topics: Adult; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Drug Administration Schedule; Drug Eruptions; Frontal Lobe; Glutamic Acid; Humans; Indoles; Magnetic Resonance Imaging; Male; Mutation; Neoplasm Staging; Proto-Oncogene Proteins B-raf; Sulfonamides; Temporal Lobe; Treatment Outcome; Valine; Vemurafenib; Xanthomatosis | 2016 |
Hominoid-specific enzyme GLUD2 promotes growth of IDH1R132H glioma.
Topics: Amino Acid Substitution; Animals; Brain Neoplasms; Cell Line, Tumor; Female; Gene Knockdown Techniques; Genes, p53; Glioma; Glutamate Dehydrogenase; Glutamic Acid; Humans; Isocitrate Dehydrogenase; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Mutant Proteins; Neoplastic Stem Cells; Receptors, Glutamate | 2014 |
Fluorescent carbonaceous nanodots for noninvasive glioma imaging after angiopep-2 decoration.
Topics: Animals; Brain Neoplasms; Chemistry Techniques, Synthetic; Diagnostic Imaging; Endosomes; Fluorescent Dyes; Glioma; Glucose; Glutamic Acid; Male; Mice, Inbred BALB C; Particle Size; Peptides; Quantum Dots; Tissue Distribution; Tumor Cells, Cultured | 2014 |
Why glioma patients seize: adding more pathological GABA to the glutamate hypothesis.
Topics: Animals; Brain Neoplasms; gamma-Aminobutyric Acid; Glioma; Glutamic Acid; Humans; Seizures | 2014 |
Acetate is a bioenergetic substrate for human glioblastoma and brain metastases.
Topics: Acetate-CoA Ligase; Acetates; Animals; Brain Neoplasms; Citric Acid Cycle; Disease Models, Animal; Glioblastoma; Glutamic Acid; Humans; Mice; Neoplasm Metastasis | 2014 |
Cell-density-dependent manifestation of partial characteristics for neuronal precursors in a newly established human gliosarcoma cell line.
Topics: Animals; Biomarkers; Brain Neoplasms; Cell Count; Cell Line, Tumor; Gliosarcoma; Glutamic Acid; Glutaminase; Humans; Karyotype; Male; Mice, Inbred BALB C; Middle Aged; Nestin; Neurons; SOXB1 Transcription Factors; Xenograft Model Antitumor Assays | 2015 |
Compensatory glutamine metabolism promotes glioblastoma resistance to mTOR inhibitor treatment.
Topics: Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Benzophenanthridines; Brain Neoplasms; Cell Line, Tumor; Citric Acid Cycle; Drug Resistance, Neoplasm; Drug Synergism; Energy Metabolism; Gas Chromatography-Mass Spectrometry; Glioblastoma; Glutamic Acid; Glutaminase; Glutamine; Glycolysis; Humans; Indoles; Ketoglutaric Acids; Magnetic Resonance Spectroscopy; Male; Metabolome; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Targeted Therapy; Neoplasm Proteins; Protein Kinase Inhibitors; Purines; RNA, Small Interfering; Rotarod Performance Test; Signal Transduction; Temporal Lobe; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays | 2015 |
The peroxisome proliferator activated receptor gamma agonist pioglitazone increases functional expression of the glutamate transporter excitatory amino acid transporter 2 (EAAT2) in human glioblastoma cells.
Topics: Anilides; Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 2; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioblastoma; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Neoplasm Transplantation; Pioglitazone; PPAR gamma; Rats; Rats, Wistar; Seizures; Thiazolidinediones | 2015 |
Glioblastoma cells induce differential glutamatergic gene expressions in human tumor-associated microglia/macrophages and monocyte-derived macrophages.
Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Astrocytes; Brain Neoplasms; Calcium-Binding Proteins; CD11b Antigen; Coculture Techniques; DNA-Binding Proteins; Gene Expression Regulation; Glioblastoma; Glutamic Acid; Humans; Leukocyte Common Antigens; Macrophages; Microfilament Proteins; Microglia; Receptors, AMPA; Tumor Cells, Cultured | 2015 |
Gas1 Knockdown Increases the Neuroprotective Effect of Glial Cell-Derived Neurotrophic Factor Against Glutamate-Induced Cell Injury in Human SH-SY5Y Neuroblastoma Cells.
Topics: Brain Neoplasms; Caspase 3; Caspase 9; Cell Cycle Proteins; Cell Death; Cell Survival; Fluorometry; Gene Knockdown Techniques; Gene Silencing; Glial Cell Line-Derived Neurotrophic Factor; Glutamic Acid; GPI-Linked Proteins; Humans; Mitochondria; Neuroblastoma; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction | 2016 |
High-Throughput Assay Development for Cystine-Glutamate Antiporter (xc-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma Cells.
Topics: Amino Acid Transport System y+; Benzoates; Brain Neoplasms; Cell Line, Tumor; Cystine; Databases, Chemical; Gene Expression Regulation, Neoplastic; Glioma; Glutamic Acid; Glycine; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Models, Biological; RNA, Messenger; Sulfasalazine; Time Factors | 2015 |
Neurodegeneration and the Brain Tumor Microenvironment. [corrected].
Topics: Amino Acid Transport Systems; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain Neoplasms; Glutamic Acid; Humans; Models, Molecular; Nerve Degeneration; Reactive Oxygen Species; Sulfasalazine; Transient Receptor Potential Channels | 2015 |
Alterations in cellular metabolome after pharmacological inhibition of Notch in glioblastoma cells.
Topics: Brain Neoplasms; Cell Line, Tumor; Cyclic S-Oxides; Glioblastoma; Glutamic Acid; Glutaminase; Homeostasis; Humans; Metabolome; Receptors, Notch; Thiadiazoles | 2016 |
Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma.
Topics: Animals; Astrocytes; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Citric Acid Cycle; Coculture Techniques; Female; Glioblastoma; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Humans; Male; Mice, Inbred NOD; Mice, SCID; Models, Biological; Neoplastic Stem Cells; Nucleotides; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Transplantation, Heterologous | 2015 |
Recurrent ganglioglioma in adults treated with BRAF inhibitors.
Topics: Adult; Brain Neoplasms; Enzyme Inhibitors; Female; Ganglioglioma; Glutamic Acid; Humans; Imidazoles; Male; Middle Aged; Mutation; Oximes; Proto-Oncogene Proteins B-raf; Valine | 2016 |
Pilot Preclinical and Clinical Evaluation of (4S)-4-(3-[18F]Fluoropropyl)-L-Glutamate (18F-FSPG) for PET/CT Imaging of Intracranial Malignancies.
Topics: Adult; Aged; Animals; Brain Neoplasms; Case-Control Studies; Cell Line, Tumor; Disease Models, Animal; Female; Fluorodeoxyglucose F18; Glioblastoma; Glutamic Acid; Heterografts; Humans; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Tomography, X-Ray Computed; Tyrosine | 2016 |
The EGF Receptor Promotes the Malignant Potential of Glioma by Regulating Amino Acid Transport System xc(-).
Topics: Amino Acid Transport System y+; Animals; Antioxidants; Apoptosis; Brain Neoplasms; Cell Membrane; Cell Movement; Cell Proliferation; Cystine; ErbB Receptors; Gene Expression Regulation, Neoplastic; Glioma; Glutamic Acid; Humans; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Reactive Oxygen Species; Sulfasalazine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2016 |
Diagnostic value of glutamate with 2-hydroxyglutarate in magnetic resonance spectroscopy for IDH1 mutant glioma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Brain Neoplasms; Glioma; Glutamate Dehydrogenase; Glutamic Acid; Glutarates; Humans; Isocitrate Dehydrogenase; Magnetic Resonance Spectroscopy; Metabolomics; Middle Aged; Mutation; Sensitivity and Specificity; Transaminases; Young Adult | 2016 |
Refined modelling of the short-T2 signal component and ensuing detection of glutamate and glutamine in short-TE, localised, (1) H MR spectra of human glioma measured at 3 T.
Topics: Adult; Algorithms; Biomarkers, Tumor; Brain Neoplasms; Computer Simulation; Female; Glioma; Glutamic Acid; Glutamine; Humans; Male; Middle Aged; Models, Biological; Models, Chemical; Proton Magnetic Resonance Spectroscopy; Reproducibility of Results; Sensitivity and Specificity; Signal Processing, Computer-Assisted | 2016 |
Advanced MRI increases the diagnostic accuracy of recurrent glioblastoma: Single institution thresholds and validation of MR spectroscopy and diffusion weighted MR imaging.
Topics: Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Cohort Studies; Diffusion Magnetic Resonance Imaging; Female; Glioblastoma; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Spectroscopy; Male; Middle Aged; ROC Curve; Statistics, Nonparametric | 2016 |
Integrative Network-based Analysis of Magnetic Resonance Spectroscopy and Genome Wide Expression in Glioblastoma multiforme.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Neoplasms; Computational Biology; Creatine; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genome-Wide Association Study; Glioblastoma; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neoplasm Proteins; Neurons; Oligodendroglia; Prognosis; Prospective Studies; Survival Analysis | 2016 |
Glutamate-Mediated Blood-Brain Barrier Opening: Implications for Neuroprotection and Drug Delivery.
Topics: 4-Aminopyridine; Adult; Aged; Animals; Blood-Brain Barrier; Brain Neoplasms; Disease Models, Animal; Double-Blind Method; Female; Glioblastoma; Glutamic Acid; Humans; Male; Middle Aged; Neuroprotective Agents; Permeability; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Seizures; Stroke; Treatment Outcome | 2016 |
Compromised GABAergic inhibition contributes to tumor-associated epilepsy.
Topics: Animals; Brain; Brain Neoplasms; Bumetanide; Cell Line, Tumor; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Glioma; Glutamic Acid; K Cl- Cotransporters; Male; Mice, Inbred C57BL; Mice, Nude; Mice, Transgenic; Phosphorylation; Rats; Sodium Potassium Chloride Symporter Inhibitors; Solute Carrier Family 12, Member 2; Symporters; Tissue Culture Techniques | 2016 |
Activating NRF1-BRAF and ATG7-RAF1 fusions in anaplastic pleomorphic xanthoastrocytoma without BRAF p.V600E mutation.
Topics: Adolescent; Astrocytoma; Brain Neoplasms; DNA Helicases; Exons; Female; Glutamic Acid; Humans; Male; Mitogen-Activated Protein Kinase Kinases; Mutation; Nuclear Proteins; Nuclear Respiratory Factor 1; Oncogene Fusion; Proto-Oncogene Proteins B-raf; raf Kinases; Signal Transduction; Time Factors; Transcription Factors; Tripartite Motif-Containing Protein 28; Tumor Suppressor Protein p53; Valine; World Health Organization; Young Adult | 2016 |
Radiotherapy induces an immediate inflammatory reaction in malignant glioma: a clinical microdialysis study.
Topics: Aged; Aged, 80 and over; Brain Neoplasms; Cytokines; Female; Glioma; Glucose; Glutamic Acid; Glycerol; Humans; Inflammation; Male; Microdialysis; Middle Aged; Radiotherapy; Statistics, Nonparametric | 2017 |
Glutamine Metabolism in Gliomas.
Topics: Brain Neoplasms; Cell Proliferation; Glioma; Glutamic Acid; Glutaminase; Glutamine; Humans; Neoplasm Invasiveness | 2016 |
BRAF V600E mutation in epilepsy-associated glioneuronal tumors: Prevalence and correlation with clinical features in a Chinese population.
Topics: Adolescent; Adult; Brain; Brain Neoplasms; Child; Child, Preschool; China; Cohort Studies; Electroencephalography; Epilepsy; Female; Glioma; Glutamic Acid; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins B-raf; Statistics as Topic; Statistics, Nonparametric; Valine; Young Adult | 2017 |
Changes in cerebral metabolism during ketogenic diet in patients with primary brain tumors:
Topics: Adult; Aged; Antineoplastic Agents, Immunological; Aspartic Acid; Bevacizumab; Brain Neoplasms; Cerebral Cortex; Diet, Ketogenic; Female; Glucose; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nutrition Assessment; Protons; Severity of Illness Index | 2017 |
In search of druggable targets for GBM amino acid metabolism.
Topics: Amino Acids; Brain Neoplasms; Databases, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioblastoma; Glutamic Acid; Humans; Metabolic Networks and Pathways; Prognosis; Survival Analysis; Urea | 2017 |
Glucose metabolites, glutamate and glycerol in malignant glioma tumours during radiotherapy.
Topics: Brain Neoplasms; Glioma; Glucose; Glutamic Acid; Glycerol; Humans; Microdialysis; Radiosurgery | 2008 |
Protein phosphatase 1, protein phosphatase 2A, and calcineurin play a role in estrogen-mediated neuroprotection.
Topics: Animals; Brain Neoplasms; Calcineurin; Calcineurin Inhibitors; Cell Line, Tumor; Cell Survival; Cyclosporine; Dicarboxylic Acids; Drug Interactions; Enzyme Inhibitors; Estrogens; Glioma; Glutamic Acid; Mice; Neurons; Neuroprotective Agents; Neurotoxins; Okadaic Acid; Oxidative Stress; Protein Phosphatase 1; Protein Phosphatase 2; Rats; Stroke | 2008 |
Two distinct tumor phenotypes isolated from glioblastomas show different MRS characteristics.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Choline; Glioblastoma; Glutamic Acid; Magnetic Resonance Spectroscopy; Phenotype; Rats; Rats, Nude | 2008 |
Cerebral metabolism during air transport of patients after surgery for malignant glioma.
Topics: Air Ambulances; Brain; Brain Neoplasms; Glioma; Glucose; Glutamic Acid; Glycerol; Humans; Lactic Acid; Microdialysis; Pyruvic Acid; Transportation of Patients | 2008 |
Cellular localization of metabotropic glutamate receptors in cortical tubers and subependymal giant cell tumors of tuberous sclerosis complex.
Topics: Adolescent; Adult; Astrocytes; Biomarkers, Tumor; Brain Neoplasms; Cerebral Cortex; Child; Child, Preschool; Female; Giant Cells; Glioma, Subependymal; Glutamic Acid; Humans; Immunohistochemistry; Infant; Male; Neurons; Protein Kinases; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; TOR Serine-Threonine Kinases; Tuberous Sclerosis; Young Adult | 2008 |
Short echo spectroscopic imaging of the human brain at 7T using transceiver arrays.
Topics: Biomarkers, Tumor; Brain; Brain Neoplasms; Equipment Design; Equipment Failure Analysis; Glutamic Acid; Humans; Image Enhancement; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Magnetics; Oligodendroglioma; Reproducibility of Results; Sensitivity and Specificity; Transducers | 2009 |
MRI and MRS of human brain tumors.
Topics: Brain Neoplasms; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy | 2009 |
The x(c)(-) cystine/glutamate antiporter (xCT) as a potential target for therapy of cancer: yet another cytotoxic anticancer approach?
Topics: Amino Acid Transport System y+; Antineoplastic Agents; Antiporters; Brain Neoplasms; Cystine; Glutamic Acid; Humans; Protein Subunits | 2009 |
Attenuated AMPA receptor expression allows glioblastoma cell survival in glutamate-rich environment.
Topics: Animals; Brain; Brain Neoplasms; Calcium; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Glioblastoma; Glutamic Acid; Humans; Immunohistochemistry; Mice; Receptors, AMPA; Sodium | 2009 |
Dual cross-talk between nitric oxide and D-serine in astrocytes and neurons in the brain.
Topics: Aging; Animals; Animals, Newborn; Astrocytes; Brain; Brain Neoplasms; Cells, Cultured; Cytokines; Glutamic Acid; Neuronal Plasticity; Neurons; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Rats, Wistar; Receptor Cross-Talk; Serine; Stress, Physiological | 2009 |
Dissection of mitogenic and neurodegenerative actions of cystine and glutamate in malignant gliomas.
Topics: Animals; Brain Neoplasms; Cell Growth Processes; Cell Line, Tumor; Cystine; Down-Regulation; Glioma; Glutamic Acid; Humans; Mice; Rats; Receptors, AMPA; Signal Transduction; Transfection | 2011 |
Stripe-like increase of rCBV beyond the visible border of glioblastomas: site of tumor infiltration growing after neurosurgery.
Topics: Adult; Aged; Asparagine; Blood Volume; Brain Neoplasms; Cerebrovascular Circulation; Contrast Media; Creatine; Female; Glioblastoma; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurosurgical Procedures; Postoperative Complications; Reproducibility of Results; Statistics, Nonparametric; Time Factors; Tritium; Young Adult | 2011 |
Impaired hippocampal synaptic plasticity in C6 glioma-bearing rats.
Topics: Animals; Body Weight; Brain Neoplasms; Cell Line, Tumor; Chromatography, High Pressure Liquid; Disease Models, Animal; Electric Stimulation; Excitatory Postsynaptic Potentials; Exploratory Behavior; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glioma; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 2011 |
[2,4-(13)C]β-hydroxybutyrate metabolism in astrocytes and C6 glioblastoma cells.
Topics: 3-Hydroxybutyric Acid; Animals; Aspartic Acid; Astrocytes; Brain Neoplasms; Citric Acid Cycle; Diet, Ketogenic; Glioblastoma; Glucose; Glutamic Acid; Glutamine; Humans; Ketone Bodies; Lactic Acid; Mice; Tumor Cells, Cultured | 2011 |
Oncogene AEG-1 promotes glioma-induced neurodegeneration by increasing glutamate excitotoxicity.
Topics: Animals; Astrocytes; Brain; Brain Neoplasms; Cell Adhesion Molecules; Cell Line, Tumor; CREB-Binding Protein; Excitatory Amino Acid Transporter 2; Glioma; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Membrane Proteins; Nerve Degeneration; Oncogenes; Promoter Regions, Genetic; Rats; RNA-Binding Proteins; YY1 Transcription Factor | 2011 |
Glutamate release by primary brain tumors induces epileptic activity.
Topics: Amino Acid Transport System y+; Analysis of Variance; Animals; Brain Neoplasms; Cell Transplantation; Electroencephalography; Electrophysiology; Epilepsy; Glioma; Glutamic Acid; Humans; Mice; Mice, SCID; Sulfasalazine | 2011 |
Glioma-related seizures: glutamate is the key.
Topics: Animals; Brain Neoplasms; Epilepsy; Glioma; Glutamic Acid; Humans | 2011 |
Immunohistochemical testing of BRAF V600E status in 1,120 tumor tissue samples of patients with brain metastases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Female; Genetic Predisposition to Disease; Glutamic Acid; HEK293 Cells; Humans; Immunohistochemistry; Male; Middle Aged; Point Mutation; Proto-Oncogene Proteins B-raf; Valine; Young Adult | 2012 |
Glutamate and tumor-associated epilepsy.
Topics: Animals; Brain Neoplasms; Epilepsy; Glutamic Acid; Humans | 2011 |
Magnetic resonance imaging of glutamate.
Topics: Adult; Animals; Brain; Brain Neoplasms; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Imaging; Male; Neuroimaging; Rats | 2012 |
Glucose metabolism via the pentose phosphate pathway, glycolysis and Krebs cycle in an orthotopic mouse model of human brain tumors.
Topics: Animals; Brain Neoplasms; Carcinoma, Renal Cell; Citric Acid Cycle; Disease Models, Animal; gamma-Aminobutyric Acid; Glioblastoma; Glucose; Glutamate Decarboxylase; Glutamic Acid; Glycolysis; Humans; Kidney Neoplasms; Lactic Acid; Magnetic Resonance Imaging; Mice; Pentose Phosphate Pathway; Positron-Emission Tomography; Xenograft Model Antitumor Assays | 2012 |
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Glioma; Glutamic Acid; Humans; Male; Mice; Mice, Nude; Oxaloacetic Acid; Rats; Rats, Sprague-Dawley; Temozolomide; Tumor Burden | 2012 |
Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo.
Topics: Animals; Brain Neoplasms; Glioblastoma; Gluconeogenesis; Glucose; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; Glycolysis; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Mitochondria; Neoplasm Transplantation; Neostriatum; Oxidation-Reduction; Phenotype; Pyruvate Carboxylase; Statistics, Nonparametric; Tumor Cells, Cultured | 2012 |
Human glioma cells induce hyperexcitability in cortical networks.
Topics: Action Potentials; Animals; Brain; Brain Neoplasms; Disease Models, Animal; Electrophysiology; Female; Glioma; Glutamic Acid; Humans; Mice; Mice, SCID; Neoplasm Transplantation; Nerve Net; Seizures; Sulfasalazine; Tumor Cells, Cultured | 2012 |
Effects of 18-kDa translocator protein knockdown on gene expression of glutamate receptors, transporters, and metabolism, and on cell viability affected by glutamate.
Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioblastoma; Glutamic Acid; Humans; Oligonucleotide Array Sequence Analysis; Rats; Receptors, GABA; Receptors, Glutamate; RNA, Small Interfering | 2012 |
Fluoxetine (prozac) and serotonin act on excitatory synaptic transmission to suppress single layer 2/3 pyramidal neuron-triggered cell assemblies in the human prefrontal cortex.
Topics: Adult; Aged; Brain Neoplasms; Excitatory Amino Acids; Excitatory Postsynaptic Potentials; Female; Fluoxetine; Glutamic Acid; Humans; Male; Middle Aged; Nerve Net; Prefrontal Cortex; Pyramidal Cells; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Serotonin; Synaptic Transmission | 2012 |
Calretinin and calbindin D-28k, but not parvalbumin protect against glutamate-induced delayed excitotoxicity in transfected N18-RE 105 neuroblastoma-retina hybrid cells.
Topics: Animals; Blotting, Western; Brain Neoplasms; Calbindin 2; Calbindins; Cell Division; Cell Line; Clone Cells; Coloring Agents; Enzyme-Linked Immunosorbent Assay; Glutamic Acid; Hybrid Cells; Immunohistochemistry; Mice; Neuroblastoma; Parvalbumins; Plasmids; Rats; Retina; S100 Calcium Binding Protein G; Tetrazolium Salts; Thiazoles; Transfection | 2002 |
Paving new pathways.
Topics: Antineoplastic Agents; Brain Neoplasms; Connexin 43; Excitatory Amino Acid Transporter 2; Glioma; Glutamic Acid; Receptors, AMPA; Receptors, Glutamate | 2002 |
Adult primitive neuroectodermal tumor: proton MR spectroscopic findings with possible application for differential diagnosis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Astrocytoma; Brain; Brain Neoplasms; Diagnosis, Differential; Female; Glioblastoma; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Meningeal Neoplasms; Meningioma; Middle Aged; Neuroectodermal Tumors, Primitive; Prospective Studies; Retrospective Studies | 2002 |
1H MR spectroscopy of mesial temporal lobe epilepsies treated with Gamma knife.
Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Epilepsy, Temporal Lobe; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Humans; Lipid Metabolism; Lipids; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Postoperative Complications; Radiation Injuries; Radiation Tolerance; Radiosurgery; Seizures; Time Factors; Treatment Failure | 2003 |
A chemometric approach for brain tumor classification using magnetic resonance imaging and spectroscopy.
Topics: Aspartic Acid; Brain; Brain Chemistry; Brain Neoplasms; Cerebrospinal Fluid; Choline; Creatine; Discriminant Analysis; Fatty Acids; Glioma; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Inositol; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Patient Selection; Principal Component Analysis; Probability; Sensitivity and Specificity; Statistical Distributions | 2003 |
Polyamine uptake in cultured cerebellar granule neurons.
Topics: Animals; Astrocytes; Biogenic Polyamines; Brain Neoplasms; Cell Line, Tumor; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Glutamic Acid; Kinetics; Membrane Potentials; Mice; Neuroblastoma; Neurons; Putrescine; Spermidine; Spermine; Synaptosomes | 2004 |
Glutamate transporter cluster formation in astrocytic processes regulates glutamate uptake activity.
Topics: Actin Cytoskeleton; Actins; Animals; Astrocytes; Brain Neoplasms; Cell Compartmentation; Cell Line, Tumor; Cell Surface Extensions; Excitatory Amino Acid Transporter 2; Glioma; Glutamic Acid; Green Fluorescent Proteins; Mice; Protein Transport; Recombinant Fusion Proteins; Sucrose; Tetradecanoylphorbol Acetate | 2004 |
Gliotoxins disrupt alanine metabolism and glutathione production in C6 glioma cells: a 13C NMR spectroscopic study.
Topics: Alanine; Alanine Transaminase; Brain Neoplasms; Cell Line, Tumor; Dicarboxylic Acids; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; gamma-Glutamyltransferase; Glioma; Gliotoxin; Glutamic Acid; Glutathione; Glycine; Humans; Immunosuppressive Agents; Indicators and Reagents; Lactic Acid; Magnetic Resonance Spectroscopy; Pyrrolidines | 2004 |
Reduced glutamine synthetase in hippocampal areas with neuron loss in temporal lobe epilepsy.
Topics: Adult; Aged; Anterior Temporal Lobectomy; Anticonvulsants; Biomarkers; Brain Neoplasms; Cell Death; Combined Modality Therapy; Epilepsy, Temporal Lobe; Excitatory Amino Acid Transporter 2; Female; Glial Fibrillary Acidic Protein; Glutamate-Ammonia Ligase; Glutamic Acid; Hippocampus; Humans; Male; Middle Aged; Neuroglia; Neurons; Sclerosis | 2005 |
Impairment of glutamate transport and increased vulnerability to oxidative stress in neuroblastoma SH-SY5Y cells expressing a Cu,Zn superoxide dismutase typical of familial amyotrophic lateral sclerosis.
Topics: Amino Acid Transport System X-AG; Amyotrophic Lateral Sclerosis; Antioxidants; Biological Transport, Active; Brain Neoplasms; Cell Line, Tumor; Electrophoresis, Agar Gel; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Kinetics; Mutation; Neuroblastoma; Oxidants; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Superoxide Dismutase; Symporters | 2005 |
Lymphocytic vasculitis mimicking aggressive multifocal cerebral neoplasm: mr imaging and MR spectroscopic appearance.
Topics: Adult; Brain; Brain Neoplasms; Choline; Diagnosis, Differential; Female; Glutamic Acid; Glutamine; Humans; Lymphocytes; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Vasculitis, Central Nervous System | 2005 |
[Proton magnetic resonance spectroscopy (1H-MRS) for the diagnosis of brain tumors and the evaluation of treatment].
Topics: Acetates; Alanine; Amino Acids; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Glutamic Acid; Glutamine; Humans; Inositol; Lactates; Magnetic Resonance Spectroscopy; Neoplasm Invasiveness; Oligodendroglioma; Phospholipids; Protons; Time Factors | 2005 |
Simultaneous detection of resolved glutamate, glutamine, and gamma-aminobutyric acid at 4 T.
Topics: Algorithms; Brain; Brain Neoplasms; Complex Mixtures; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Neurotransmitter Agents | 2007 |
Metabolite findings in tumefactive demyelinating lesions utilizing short echo time proton magnetic resonance spectroscopy.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Demyelinating Diseases; Diagnosis, Differential; Echo-Planar Imaging; Female; Glutamic Acid; Humans; Lactic Acid; Male; Middle Aged; Multiple Sclerosis; Protons | 2007 |
DNA methylation dependent silencing of the human glutamate transporter EAAT2 gene in glial cells.
Topics: Animals; Astrocytes; Brain; Brain Chemistry; Brain Neoplasms; Cells, Cultured; CpG Islands; DNA Methylation; Epigenesis, Genetic; Excitatory Amino Acid Transporter 2; Gene Silencing; Genes, Reporter; Glioma; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; HeLa Cells; Humans; Neuroglia; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley | 2007 |
Increase in glutamate as a sensitive indicator of extracellular matrix integrity in peritumoral edema: a 3.0-tesla proton magnetic resonance spectroscopy study.
Topics: Aged; Aged, 80 and over; Brain Edema; Brain Neoplasms; Case-Control Studies; Extracellular Matrix; Female; Glioma; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Meningioma; Middle Aged | 2007 |
Autocrine glutamate signaling promotes glioma cell invasion.
Topics: Amino Acid Transport System y+; Animals; Brain Neoplasms; Calcium; Cell Line, Tumor; Cell Movement; Female; Glioblastoma; Glutamic Acid; Humans; Mice; Mice, Nude; Neoplasm Invasiveness; Random Allocation; Receptors, AMPA; Signal Transduction; Sulfasalazine | 2007 |
Spectral simplification for resolved glutamate and glutamine measurement using a standard STEAM sequence with optimized timing parameters at 3, 4, 4.7, 7, and 9.4T.
Topics: Animals; Brain; Brain Neoplasms; Computer Simulation; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Phantoms, Imaging; Rats; Rats, Sprague-Dawley | 2008 |
Human herpesvirus 6 (HHV-6) induces dysregulation of glutamate uptake and transporter expression in astrocytes.
Topics: Astrocytes; Astrocytoma; Brain Neoplasms; Cell Line, Tumor; Cells, Cultured; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Gene Expression Regulation, Viral; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glycoproteins; Herpesvirus 6, Human; Humans; Immediate-Early Proteins; Reverse Transcriptase Polymerase Chain Reaction; Viral Core Proteins; Virus Latency; Virus Replication | 2008 |
Tetramethylpyrazine inhibits activities of glioma cells and glutamate neuro-excitotoxicity: potential therapeutic application for treatment of gliomas.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Coculture Techniques; Glioma; Glutamic Acid; Microdialysis; Nerve Degeneration; Neurons; Pyrazines; Rats; Rats, Sprague-Dawley; Xenograft Model Antitumor Assays | 2008 |
Drug assessment based on detection of L-glutamate released from C6 glioma cells using an enzyme-luminescence method.
Topics: 4-Aminopyridine; Animals; Brain Neoplasms; Carbamazepine; Cell Line, Tumor; Enzymes; Flunarizine; Glioma; Glutamic Acid; Lidocaine; Luminescence; Nickel; Nifedipine; Rats; Veratridine | 2008 |
Imaging of brain tumors after administration of L-(N-13)glutamate: concise communication.
Topics: Adolescent; Adult; Blood-Brain Barrier; Brain Neoplasms; Child; Female; Glutamates; Glutamic Acid; Humans; Male; Nitrogen Radioisotopes; Sodium Pertechnetate Tc 99m; Technetium; Tomography, Emission-Computed; Tomography, X-Ray Computed | 1982 |
Effect of cocaine on macromolecular syntheses and cell proliferation in cultured glial cells.
Topics: Animals; Animals, Newborn; Brain Neoplasms; Cell Division; Cells, Cultured; Cocaine; DNA; Glioma; Glutamates; Glutamic Acid; L-Lactate Dehydrogenase; Leucine; Nerve Tissue Proteins; Neuroglia; Rats; Rats, Sprague-Dawley; RNA; Thymidine; Trypan Blue; Tumor Cells, Cultured; Uridine | 1993 |
BCL-2 blocks glutamate toxicity in neural cell lines.
Topics: Animals; Brain Neoplasms; Cell Line, Transformed; Cell Survival; Cerebellum; CHO Cells; Cricetinae; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Humans; Mice; Neurons; Neurotoxins; PC12 Cells; Potassium Chloride; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogenes; Rats; Transfection | 1993 |
High-resolution 1H-magnetic resonance spectroscopy of pediatric posterior fossa tumors in vitro.
Topics: Adolescent; Alanine; Amino Acids; Animals; Aspartic Acid; Astrocytoma; Brain Neoplasms; Cerebellar Neoplasms; Child; Child, Preschool; Choline; Cranial Fossa, Posterior; Glutamates; Glutamic Acid; Humans; In Vitro Techniques; Infant; Magnetic Resonance Spectroscopy; Medulloblastoma; Neuroectodermal Tumors; Neurotransmitter Agents; Rats; Valine | 1994 |
Proton MR spectroscopy of experimental brain tumors in vivo.
Topics: Animals; Aspartic Acid; Blood Glucose; Brain Edema; Brain Neoplasms; Caudate Nucleus; Cell Line; Choline; Creatinine; Energy Metabolism; Glioma; Glutamic Acid; Inositol; Magnetic Resonance Imaging; Male; Neoplasm Transplantation; Neurilemmoma; Neuroblastoma; Phosphocreatine; Rats; Rats, Inbred F344 | 1994 |
Human epileptic astrocytes exhibit increased gap junction coupling.
Topics: Astrocytes; Astrocytoma; Brain Neoplasms; Calcium; Cerebral Cortex; Culture Techniques; Electroencephalography; Epilepsy; Gap Junctions; Glutamic Acid; Humans; Magnetic Resonance Imaging; Microscopy, Fluorescence; Temporal Lobe | 1995 |
Characteristic metabolic profiles revealed by 1H NMR spectroscopy for three types of human brain and nervous system tumours.
Topics: Alanine; Amino Acids; Brain Neoplasms; Choline; Chromatography, High Pressure Liquid; Creatine; Glioblastoma; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Meningioma; Neuroblastoma; Tumor Cells, Cultured | 1995 |
Reactive oxygen species involved in the glutamate toxicity of C6 glioma cells via xc antiporter system.
Topics: Adenosine Triphosphate; Animals; Antiporters; Brain Neoplasms; Cell Death; Cell Nucleus; Cystine; DNA Damage; Free Radical Scavengers; Glioma; Glutamate-Ammonia Ligase; Glutamic Acid; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenases; Lipid Peroxides; Rats; Reactive Oxygen Species; Tumor Cells, Cultured | 1996 |
Effect of 6-aminonicotinamide on metabolism of astrocytes and C6-glioma cells.
Topics: 6-Aminonicotinamide; Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Brain Neoplasms; Cells, Cultured; Enzyme Inhibitors; Glioma; Glucose; Glutamic Acid; Lactic Acid; Nerve Tissue Proteins; Phosphocreatine; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured | 1997 |
Characterization of metabotropic glutamate receptors in rat C6 glioma cells.
Topics: Animals; Brain Neoplasms; Cell Membrane; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glioma; Glutamic Acid; Guanylyl Imidodiphosphate; Kinetics; Neuroprotective Agents; Radioligand Assay; Rats; Receptors, Metabotropic Glutamate; Tumor Cells, Cultured | 1997 |
Novel anti-brain tumor cytotoxins specific for cancer cells.
Topics: Antineoplastic Agents; Brain Neoplasms; Carrier Proteins; Cell Division; Cytotoxins; Exotoxins; Glioma; Glutamic Acid; Humans; Interleukin-13; Interleukin-13 Receptor alpha1 Subunit; Lysine; Mutation; Plasmids; Pseudomonas aeruginosa; Receptors, Cell Surface; Receptors, Interleukin; Receptors, Interleukin-13; Recombinant Fusion Proteins; Tumor Cells, Cultured | 1998 |
Intraoperative microdialysis and tissue-pO2 measurement in human glioma.
Topics: Aspartic Acid; Brain Edema; Brain Neoplasms; Cell Death; Female; Frontal Lobe; Glioblastoma; Glutamic Acid; Humans; Male; Microdialysis; Monitoring, Intraoperative; Oxygen Consumption; Prognosis; Temporal Lobe | 1998 |
Lactate turnover in rat glioma measured by in vivo nuclear magnetic resonance spectroscopy.
Topics: Animals; Brain Neoplasms; Carbon Isotopes; Glioma; Glucose; Glutamic Acid; Glycolysis; Lactic Acid; Magnetic Resonance Spectroscopy; Rats | 1998 |
[1-(13)C]glucose metabolism in the tumoral and nontumoral cerebral tissue of a glioma-bearing rat.
Topics: Alanine; Amino Acids; Analysis of Variance; Animals; Aspartic Acid; Body Weight; Brain; Brain Neoplasms; Carbon Isotopes; Citric Acid Cycle; Female; Functional Laterality; gamma-Aminobutyric Acid; Glioma; Glucose; Glutamic Acid; Glutamine; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Models, Chemical; Nerve Tissue Proteins; Rats; Rats, Wistar; Tumor Cells, Cultured | 1999 |
Characterization of neocortical and hippocampal synaptosomes from temporal lobe epilepsy patients.
Topics: Adult; Animals; Brain Neoplasms; Calcium; Epilepsy, Temporal Lobe; Female; gamma-Aminobutyric Acid; GAP-43 Protein; Glial Fibrillary Acidic Protein; Glutamic Acid; Hippocampus; Humans; Male; Membrane Potentials; Neocortex; Nerve Tissue Proteins; Phosphorylation; Potassium; Rats; Synaptosomes | 1999 |
Inhibitory effects of constituents of Gastrodia elata Bl. on glutamate-induced apoptosis in IMR-32 human neuroblastoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Calcium; Calcium Signaling; Chelating Agents; DNA Fragmentation; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Neuroblastoma; Tumor Cells, Cultured | 1999 |
Compromised glutamate transport in human glioma cells: reduction-mislocalization of sodium-dependent glutamate transporters and enhanced activity of cystine-glutamate exchange.
Topics: Amino Acid Substitution; Amino Acid Transport System X-AG; Animals; Astrocytes; ATP-Binding Cassette Transporters; Benzoates; Brain Neoplasms; Cells, Cultured; Cystine; Excitatory Amino Acid Antagonists; Glioma; Glucose Transporter Type 1; Glutamic Acid; Glycine; Humans; Monosaccharide Transport Proteins; Rats; Rats, Sprague-Dawley; Sodium; Tissue Distribution | 1999 |
Extracellular glutamate and other metabolites in and around RG2 rat glioma: an intracerebral microdialysis study.
Topics: Amino Acids; Animals; Ascorbic Acid; Brain Chemistry; Brain Neoplasms; Extracellular Space; Female; Glioma; Glucose; Glutamic Acid; Lactic Acid; Magnetic Resonance Imaging; Microdialysis; Rats; Rats, Inbred F344; Uric Acid | 2000 |
High glycolytic activity in rat glioma demonstrated in vivo by correlation peak 1H magnetic resonance imaging.
Topics: Alanine; Animals; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Ethanolamines; Female; Glioma; Glucose; Glutamic Acid; Glutamine; Glycolysis; Lactic Acid; Magnetic Resonance Imaging; Phosphocreatine; Rats; Rats, Sprague-Dawley; Taurine; Tumor Cells, Cultured | 2001 |
Excitotoxic destruction facilitates brain tumor growth.
Topics: Animals; Brain Neoplasms; Glioma; Glutamic Acid; Humans; N-Methylaspartate | 2001 |
Glutamate release promotes growth of malignant gliomas.
Topics: Amino Acid Transport System X-AG; Animals; Brain Neoplasms; Carrier Proteins; Cell Division; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glioma; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Luminescent Measurements; Male; Memantine; Neoplasm Transplantation; Neurons; Rats; Rats, Inbred F344; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Symporters; Tumor Cells, Cultured | 2001 |
Dysembryoplastic neuroepithelial tumour (DNT). Is the mechanism of seizures related to glutamate? An immunohistochemical study.
Topics: Adult; Brain Neoplasms; Glutamic Acid; Humans; Immunohistochemistry; Male; Neoplasms, Neuroepithelial; Seizures; Teratoma | 2001 |
Magnetic resonance spectroscopy and metabolism. Applications of proton and 13C NMR to the study of glutamate metabolism in cultured glial cells and human brain in vivo.
Topics: Animals; Astrocytes; Brain; Brain Edema; Brain Neoplasms; Cell Line; Glioma; Glutamates; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Neuroglia; Neurotransmitter Agents; Tumor Cells, Cultured | 1991 |
Ionic concentration of shifting fluid during glutamate-induced swelling of cultured glioma cells estimated by the cytocrit technique.
Topics: Animals; Brain Neoplasms; Electrolytes; Glioma; Glutamates; Glutamic Acid; Intracellular Fluid; Osmolar Concentration; Rats; Tumor Cells, Cultured | 1990 |
Aspartame. Review of safety issues. Council on Scientific Affairs.
Topics: Adolescent; Adult; Animals; Aspartame; Aspartic Acid; Brain Chemistry; Brain Diseases; Brain Neoplasms; Carbonated Beverages; Carcinogens; Child; Dietary Carbohydrates; Diketopiperazines; Dipeptides; Drug Stability; Endocrine System Diseases; Female; Glutamates; Glutamic Acid; Humans; Infant; Intellectual Disability; Methanol; Mice; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Piperazines; Pregnancy; Rats | 1985 |
Effect of glutamate analogues on brain tumor cell lines.
Topics: 2-Aminoadipic Acid; Aminobutyrates; Brain Neoplasms; Cell Division; Cell Line; Glioma; Glutamates; Glutamic Acid; Glutamine; Homocysteine; Medulloblastoma; Neuroglia; Sarcoma | 1985 |