glutamic acid and Brain Injuries

glutamic acid has been researched along with Brain Injuries in 316 studies

Research

Studies (316)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (2.53)	18.7374
1990's	55 (17.41)	18.2507
2000's	142 (44.94)	29.6817
2010's	90 (28.48)	24.3611
2020's	21 (6.65)	2.80

Authors

Authors	Studies
Bai, F; Hu, N; Huang, J; Li, CL; Ma, S; Qu, LY; Wang, JH; Yang, BF; Yang, R	1
Beeraka, NM; Bulygin, KV; Fan, R; Greeshma, MV; Huria, T; Kumar, P; Liu, J; Nikolenko, VN; Sinelnikov, MY; Sukocheva, O; Uthaiah, CA; Vikram, PRH	1
Andrew, RD; Ayata, C; Brennan, KC; Dawson-Scully, KD; Dreier, JP; Farkas, E; Hartings, JA; Herreras, O; Kirov, SA; Müller, M; Ollen-Bittle, N; Reiffurth, C; Revah, O; Robertson, RM; Ullah, G	1
Fushimi, M; Kawase, H; Mizoue, R; Morimatsu, H; Murai, S; Sato, S; Takasugi, Y; Takeda, Y	1
Date, I; Fushimi, M; Haruma, J; Hiramatsu, M; Hishikawa, T; Kawase, H; Kidani, N; Morimatsu, H; Murai, S; Okura, Y; Sugiu, K; Takahashi, Y; Takeda, Y	1
Cai, W; Chen, C; Huang, Y; Li, S; Li, Y; Lin, S; Lu, B; Ning, X; Pi, J; Qi, T; Sheng, L; Wang, K; Wei, C; Xue, D; Yan, G; Yin, W; Zhou, Y; Zhu, Z	1
Chen, CC; Chen, WP; Hsu, PC; Lan, YJ; Lee, LY; Lee, YH; Wang, YC	1
Du, Z; He, W; Jiang, X; Liu, S; Qin, Q; Wang, C; Wang, J; Wang, T; Wang, Y; Wang, Z; Wu, J; Xu, Z; Yan, X; Yuan, S; Zhang, H	1
Chen, X; Huang, ZZ; Ning, YL; Peng, Y; Tan, SW; Yang, N; Zhou, YG	1
Cardona-Gómez, GP; Gutierrez-Vargas, JA; Oluwatomilayo-Ojo, P; Perez-Corredor, PA	1
Asada, R; Kanamaru, H; Kawakita, F; Nakajima, H; Nampei, M; Oinaka, H; Suzuki, H; Suzuki, Y	1
Boyko, M; Fleidervish, I; Frenkel, A; Gruenbaum, BF; Zlotnik, A	1
Pavlinova, EB; Savchenko, OA	1
Andescavage, N; Basu, SK; Chang, T; duPlessis, AJ; Kapse, KJ; Limperopoulos, C; Lopez, CA; Murnick, J; Pradhan, S; Sharker, YM	1
Feng, D; Gao, G; Guo, K; Qin, H; Tao, K; Wu, L; Zhang, Z; Zhou, J	1
Hwang, K; Jang, JH; Jung, K; Kim, IS; Kim, M; Ko, Y; Park, KI; Shin, JE	1
Kosari-Nasab, M; Salari, AA; Shokouhi, G	1
Pushchina, EV; Varaksin, AA; Zharikova, EI	1
Brigati, G; De Angelis, LC; Maghnie, M; Malova, M; Massirio, P; Minghetti, D; Parodi, A; Polleri, G; Ramenghi, LA; Rossi, A; Traggiai, C	1
Caporale, A; Culmsee, C; Dolga, AM; Doti, N; Farina, B; Fattorusso, R; Mascanzoni, F; Monti, A; Russo, L; Ruvo, M	1
Avila-Luna, A; Bueno-Nava, A; García-Díaz, G; González-Piña, R; Montes, S; Parra-Cid, C; Ramos-Languren, LE; Rodríguez-Labrada, R; Vázquez-Mojena, Y	1
Cui, X; Hu, YY; Li, L; Li, SQ; Li, WB; Qi, J; Sun, XC; Xian, XH; Zhang, M	1
Balu, DT; Coyle, JT; Liebl, DJ; Loris, ZB; Perez, EJ; Sick, TJ; Tapanes, SA	1
Baranenko, DD; Fu, CY; Li, FY; Lu, GW; Song, BW; Wang, EJ; Zhou, AY	1
Bylicky, MA; Day, RM; Mueller, GP	1
An, JH; Chen, JF; Dai, SS; Li, W; Ning, YL; Wang, H; Yang, N; Zhou, YG; Zhu, PF	1
Freire, MA	1
Greig, NH; Li, Y; Pick, CG; Rachmany, L; Rubovitch, V; Tweedie, D; Wang, JY; Yu, QS	1
Cohen, AS; Elkind, J; Galante, R; Kuzma, NN; Lian, J; Lim, MM; Pack, AI; Rodin, J; Xiong, G; Zhang, L; Zhu, J	1
Bennet, L; Fraser, M; Gunn, AJ; Mitchell, MD; Weaver-Mikaere, L	1
Babb, JS; Gonen, O; Grossman, RI; Haemer, G; Kierans, AS; Kirov, II; Lui, YW; Nisenbaum, E	1
Jiang, R; Si, D; Wang, H; Yang, P; Zhang, Y; Zhou, H	1
Galloway, MP; Ghoddoussi, F; Hall, CS; Perrine, SA; Sajja, VS; VandeVord, PJ	1
Andresen, L; Cantu, D; Dulla, CG; Hampton, D; Taylor-Weiner, A; Tesco, G; Walker, K	1
Dong, Y; Feng, D; Gao, G; Huang, J; Ma, Y; Qin, H; Wang, W; Wu, L; Wu, S; Zhang, Z	1
Chen, TH; Lin, CJ; Shih, CM; Yang, LY	1
Brandi, G; Fasshauer, M; Fendel, A; Nägeli, M; Sommerfeld, J; Stover, JF	1
Griesmaier, E; Hermann, M; Kiechl-Kohlendorfer, U; Obermair, GJ; Posod, A; Stanika, RI; Urbanek, M; Wechselberger, K; Wegleiter, K	1
Chen, J; Chen, W; Hu, H; Huang, Y; Leng, T; Liu, A; Qiu, P; Sang, H; Tang, L; Wang, L; Wang, Y; Yan, G; Yin, W; You, X; Zhang, J; Zhou, Y	1
Hagenston, AM; Haux, D; Hertle, DN; Jungk, C; Sakowitz, OW; Santos, E; Unterberg, AW	1
Marques-Vidal, P; Oddo, M; Patet, C; Quintard, H; Suys, T	1
Dienel, GA	1
Fievisohn, EM; Hardy, WN; Sajja, VS; Vandevord, PJ	1
Bondy, SC; Prasad, KN	1
Giza, CC; Guerriero, RM; Rotenberg, A	1
DiNapoli, VA; Gerhardt, GA; Hartings, JA; Hinzman, JM; Mahoney, EJ	1
Aleksandrova, EV; Potapov, AA; Zaytsev, OS	1
Chang, S; Gao, W; Gao, YX; Liao, H; Pang, T; Qiu, WW; Wang, YJ; Wang, YY; Xu, Y; Xu, YZ; Yang, LF; Yu, LG; Zhang, LY	1
Akai, T; Iizuka, H; Ishigaki, Y; Kato, N; Liu, X; Shui, Y; Tajima, N; Uchiumi, O; Wang, M; Zou, J	1
Fink, B; Kraitsy, K; Molcanyi, M; Paier-Pourani, J; Patz, S; Schäfer, U; Üçal, M; Weidinger, A	1
Burd, I; Johnston, MV; Kannan, G; Welling, J	1
Banton, R; Benjamin, R; Piehler, T; Zander, NE	1
Carvalho, F; Carvalho, RA; Cunha, RA; Fonseca, R; Fontes Ribeiro, CA; Jarak, I; Köfalvi, A; Lemos, C; Pereira, FC; Pita, IR; Prediger, RD; Sequeira, AC; Silva, CD	1
Akinyemi, A; Michel, G; Sanchez-Gonzalez, MA; Sterkel, S	1
Kimelberg, HK	1
Alessandri, B; Heimann, A; Hoelper, B; Kempski, O; Meissner, A; Timaru-Kast, R	2
Ueda, Y; Willmore, LJ	1
Fischer, JP; Hartley, CE; Riccardi, R; Shah, S; Strauss, JA; Varma, M; Yang, ZJ; Zhang, S	1
An, J; Chen, J; Chen, X; Dai, S; Li, P; Li, W; Liu, P; Wang, H; Xiong, R; Zhao, Y; Zhou, Y; Zhu, P	1
Banerjee, R; Garg, SK; Kipnis, J	1
Chou, J; Delvolve, A; Harvey, BK; Hoffer, BJ; Jackson, SN; Kuo, CC; Post, J; Shen, H; Wang, Y; Woods, AS	1
Doezema, D; Elgie, R; Gasparovic, C; Ling, J; Mannell, M; Mayer, AR; Phillips, J; Yeo, R	1
Besson, VC	1
Fujii, M; Fujisawa, H; Kajiwara, K; Kato, S; Koizumi, H; Nomura, S; Suzuki, M	1
Fiskum, G; Hopkins, I; McKenna, M; O'Brien, J; Robertson, C; Scafidi, S	1
Alonso, OF; Atkins, CM; Bramlett, HM; Dietrich, WD; Falo, MC	1
Buriticá, E; Escobar, MI; García-Cairasco, N; Guzmán, F; Pimienta, HJ; Villamil, L	1
Carpenter, KL; Gallagher, CN; Grice, P; Howe, DJ; Hutchinson, PJ; Kirkpatrick, PJ; Mason, A; Menon, DK; Pickard, JD; Sutherland, GR; Timofeev, I	1
Berman, RF; Gurkoff, GG; Lyeth, BG; Muizelaar, JP; Shahlaie, K	1
Arevalo, MA; Azcoitia, I; Bellini, MJ; Garcia-Segura, LM; Santos-Galindo, M	1
Cohen, AS; Cole, JT; Elkind, JA; Kundu, S; Mitala, CM; Nissim, I; Verma, A	1
Hunt, RF; Scheff, SW; Smith, BN	1
Chamoun, R; Goodman, JC; Gopinath, SP; Robertson, C; Suki, D	1
Béchir, M; Brandi, G; Haberthür, C; Ludwig, S; Meierhans, R; Sommerfeld, J; Stocker, R; Stover, JF	1
Burmeister, JJ; Gerhardt, GA; Hinzman, JM; Huettl, P; Lifshitz, J; Pomerleau, F; Quintero, JE; Thomas, TC	1
Bertrand, A; Dentresangle, C; Detraz, I; Dzahini, K; Le Cavorsin, M; Leviel, V; Savasta, M	1
An, JH; Chen, JF; Chen, XY; Dai, SS; Li, P; Li, W; Liu, P; Wang, H; Yang, N; Zhao, Y; Zhou, YG	1
Danscher, G; Doering, P; Larsen, A; Penkowa, M; Rungby, J; Stoltenberg, M	1
An, JH; Chen, JF; Chen, XY; Dai, SS; Li, P; Li, W; Liu, P; Shen, HY; Xiong, RP; Yang, N; Zhao, Y; Zhou, YG; Zhu, PF	1
Bor-Seng-Shu, E; de Lima Oliveira, M; Teixeira, MJ	1
Andriessen, TM; Jacobs, B; Vos, PE	1
Abe, Y; Kawai, N; Kawakita, K; Kuroda, Y; Tamiya, T; Yano, T	1
Bartnik-Olson, BL; Hovda, DA; Oyoyo, U; Sutton, RL	1
Chen, XY; Dai, SS; Li, P; Ning, YL; Yang, N; Zhao, Y; Zhou, YG	1
Al-Rawi, PG; Carpenter, KL; Czosnyka, M; Gupta, AK; Hutchinson, PJ; Kirkpatrick, PJ; Menon, DK; Nortje, J; O'Connell, MT; Pickard, JD; Smielewski, P; Timofeev, I	1
Kofke, WA; Larach, DB; Le Roux, P	1
Kelley, BG; Luoma, JI; Mermelstein, PG	1
Jensen, FE; Kinney, HC; Rosenberg, PA; Volpe, JJ	1
Hasebe, S; Ogita, K; Shiba, T; Yoneyama, M	1
Fuse, A; Kushimoto, S; Masuno, T; Matsumoto, G; Onda, H; Watanabe, A; Yokobori, S; Yokota, H	1
Firestein, BL; Kutzing, MK; Luo, V	2
Fei, F; Fei, Z; Luo, P; Qu, Y; Zhang, L	1
Kiening, KL; Sakowitz, OW; Simunovic, F; Unterberg, AW; Zweckberger, K	1
Boellaard, R; Folkersma, H; Foster Dingley, JC; Huisman, MC; Lammertsma, AA; Molthoff, CF; Rozemuller, A; van Berckel, BN; Vandertop, WP	1
Balakhadze, I; Eitzen, S; Fischer, B; Gorji, A; Greiner, C; Grimmelt, AC; Schiffbauer, H; Wölfer, J	1
Bae, K; Hwang, BY; Jeong, HY; Kim, JY; Kim, S; Lee, HK; Seong, YH	1
Halámek, J; Katz, E; Valdés-Ramírez, G; Wang, J; Windmiller, JR; Zhou, M; Zhou, N	1
Ha-Huy, R; Stover, JF; Tanner, M; Vuille-Dit-Bille, RN	1
Gerhardt, GA; Hinzman, JM; Lifshitz, J; Thomas, TC	1
Boyko, M; Dubilet, M; Gruenbaum, BF; Gruenbaum, SE; Klin, Y; Kotz, R; Leibowitz, A; Ohayon, S; Shapira, Y; Teichberg, VI; Zlotnik, A	1
Pan, XD; Wei, J; Xiao, GM	1
Hillman, J; Mellergård, P; Sjögren, F	1
Egea-Guerrero, JJ; Muñoz-Sánchez, MA; Murillo-Cabezas, F; Revuelto-Rey, J	1
Hackenberg, K; Hertle, DN; Jung, CS; Kiening, KL; Sakowitz, OW; Unterberg, AW; Zweckberger, K	1
Agyapomaa, DA; Bellander, BM; Hellewell, SC; Morganti-Kossmann, MC; Yan, EB	1
Kostandy, BB	1
Boyko, M; Dubilet, E; Dubilet, M; Gruenbaum, BF; Gruenbaum, SE; Leibowitz, A; Ohayon, S; Regev, A; Shapira, Y; Sinelnikov, I; Teichberg, VI; Zlotnik, A	1
Bleichner, JP; Laviolle, B; Malledant, Y; Morandi, X; Seguin, P; Tanguy, M	1
Gerhardt, GA; Hinzman, JM; Lifshitz, J; Quintero, JE; Thomas, TC	1
Ashpole, NM; Brustovetsky, N; Brustovetsky, T; Cummins, TR; Engleman, EA; Hudmon, A; Song, W	1
Carpenter, KL; Czosnyka, M; Hutchinson, PJ; Nortje, J; Pickard, JD; Timofeev, I	1
Kumaria, A; Tolias, CM	1
Armstead, WM; Cines, DB; Higazi, AA; Riley, J; Smith, DH; Yarovoi, S	1
Etchepare, M; McArthur, DL; Stein, NR; Vespa, PM	1
Nuñez, J	1
Gurkoff, GG; Lyeth, BG; Shahlaie, K	1
Moritz, C; Peri, F; Prykhozhij, S; Sieger, D; Ziegenhals, T	1
Borgens, RB; Liu-Snyder, P	1
Borisova, T; Kasatkina, L; Krisanova, N; Sivko, R	1
Czosnyka, M; Sakowitz, OW; Sánchez-Porras, R; Santos, E; Unterberg, AW; Zheng, Z	1
Griesmaier, E; Gross, M; Hermann, M; Keller, M; Kiechl-Kohlendorfer, U; Neubauer, V; Posod, A; Urbanek, M; Wegleiter, K	1
Benhamou, D; Blanié, A; Duranteau, J; Geeraerts, T; Vigué, B	1
Alessandri, B; Heimann, A; Kamada, Y; Kempski, O; Nagata, M; Schwandt, E	1
Hirbec, H; Kamenka, JM; Mausset, AL; Privat, A; Vignon, J	1
Brinker, T; Samii, M; Schuhmann, MU; Skardelly, M; Stiller, D; Thomas, S	1
Sakowitz, OW; Stover, JF; Unterberg, AW	1
Furuya, Y; Goodman, JC; Hlatky, R; Robertson, CS; Valadka, AB	1
Armstead, WM; Kulkarni, M	1
Braddock, JF; Castellani, RJ; Drew, KL; Hu, Y; Smith, MA; Zhou, F; Zhu, X	1
Bullian, L; Carlier, P; Dixon, CE; Kochanek, P; Marion, DW; Puccio, A; Wisniewski, SR	1
Prough, DS; Zornow, MH	1
Kroppenstedt, SN; Sakowitz, OW; Stover, JF; Thomale, UW; Unterberg, AW	1
DeLorenzo, RJ; Limbrick, DD; Sombati, S	1
McIntosh, TK; Royo, NC; Schouten, JW; Shimizu, S; Stover, JF	1
Chen, Y; Swanson, RA	1
Budd, SL; Gillessen, T; Lipton, SA	1
Diaz-Parejo, P; Nordström, CH; Reinstrup, P; Ståhl, N; Ungerstedt, U; Xu, W	1
Buffenoir, K; Lapierre, F; Wager, M	1
Bowery, NG; Richards, DA; Sgouros, S; Tolias, CM	1
Bilger, J; Buck, CR; Gupta, DK; Jurynec, MJ; Law, AK; McKeon, RJ; Wallace, DC	1
Asakura, T; Atsumi, T; Furukawa, T; Hoshino, S; Kobayashi, S; Takahashi, M; Teramoto, A	1
Ikonomidou, C; Turski, L	1
Alves, OL; Bullock, R; Clausen, T; Doyle, AJ; Gilman, C	1
Beyer, TF; Dohse, NK; Kroppenstedt, SN; Sakowitz, OW; Schaser, KD; Stover, JF; Thomale, UW; Unterberg, AW	1
Chen, CJ; Liao, SL	1
Chen, HZ; Wang, ZJ; Xia, M; Xue, QS; Yu, BW	1
Bernarding, J; Brinker, T; Klinge, PM; Samii, A; Samii, M; Schuhmann, MU; Skardelly, M; Stiller, D	1
BIRKMEYER, W	1
LINDENBERG, W; VON GEBHARDT, M	1
BRETSCHNEIDER, R; GRUENDIG, E; SALVENMOSER, F	1
Callsen, TA; Kiening, KL; Sarrafzadeh, AS; Unterberg, AW	1
Enyu, L; Hongmin, B; Xiang, Z; Zhou, F	1
Hayashi, Y; Inoue, K; Kadowaki, T; Kagamiishi, Y; Katsube, N; Mizoguchi, Y; Moriguchi, S; Nabekura, J; Nakanishi, H; Tomimatsu, Y; Watanabe, S; Yamamoto, K	1
Alessandri, B; Filippi, R; Heimann, A; Kempski, O; Kopacz, L	1
THOMAS, J	1
Bayir, H; Kochanek, PM; Puccio, A; Ren, D; Wagner, AK; Zafonte, RD	1
Stys, PK	1
Bambrick, L; Fiskum, G; Kristian, T	1
Arundine, M; Tymianski, M	1
Culic, M; Filipovic, R; Milenkovic, I; Nedeljkovic, N; Pekovic, S; Rakic, L; Stojiljkovic, M	1
Ai, J; Baker, A	1
Flügge, G; Kempski, OS; Kroppenstedt, SN; Sakowitz, OW; Stover, JF; Thomale, UW; Unterberg, AW	1
Ashwal, S; Gross, M; Holshouser, B; Kido, D; Osterdock, R; Serna, T; Tong, K	2
Bernal, F; Fredriksson, K; Mahy, N; Ramonet, D; Rodríguez, MJ	1
Vespa, P	1
Contant, CF; Goodman, JC; Hlatky, R; Robertson, CS; Valadka, AB	1
Hazell, AS; Pow, DV; Yi, JH	1
Bellander, BM; Cantais, E; Enblad, P; Hutchinson, P; Nordström, CH; Olsen, NV; Robertson, C; Sahuquillo, J; Smith, M; Stocchetti, N; Ungerstedt, U; Unterberg, A	1
Bauer, R; Fritz, H	1
Guo, YW; Xu, RX	1
Holshouser, BA; Shutter, L; Tong, KA	1
Fabio, A; Hirschberg, R; Li, W; Marion, DW; Puccio, AM; Wagner, AK; Zafonte, RD	1
Bai, HM; Fei, Z; Huang, WD; Jiang, XF; Zhang, X	1
Alves, OL; Bullock, R; Clausen, T; Reeves, TM; Reinert, M	1
Johnston, MV	1
Domercq, M; Matute, C; Sánchez-Gómez, MV	1
Bartnik, BL; Fukushima, M; Harris, NG; Hovda, DA; Lee, SM; Sutton, RL	1
Auberson, YP; DeRidder, MN; Meaney, DF; Raghupathi, R; Siman, R; Simon, MJ	1
Anderson, C; Hillman, J; Mellergård, P; Milos, P; Sjögren, F; Yu, ZQ	1
Hazell, AS; Hoover, R; McIntosh, TK; Yi, JH	1
Egberts, H; Groenendaal, F; Hopman, J; Ruitenbeek, W; van Bel, F; van de Bor, M; van den Tweel, E; van Os, S	1
Hazell, AS; Yi, JH	1
Akasu, T; Cao, R; Hasuo, H; Ooba, S; Zhang, X	1
Berman, RF; Bzdega, T; Jiang, J; Kozikowski, AP; Lyeth, BG; Neale, JH; O'Connor, WT; Smyth, A; Van, KC; Zhao, X; Zhong, C; Zhou, J	1
Bonislawski, DP; Cohen, AS; Schwarzbach, E; Xiong, G	1
Kiening, KL; Neher, M; Sakowitz, OW; Schardt, C; Stover, JF; Unterberg, AW	1
Arciniegas, DB; Silver, JM	1
Giza, CC; Hovda, DA; Maria, NS	1
Bullock, RM; Choi, S; Gilman, C; Kunene, NK; Mazzeo, AT	1
DeLorenzo, RJ; Deshpande, LS; Sun, DA	1
Binder, DK; Steinhäuser, C	1
Bullock, R; Choi, S; Doppenberg, E; Khaldi, A; Reinert, M; Zauner, A	2
Ashwal, S; Babikian, T; Burley, T; Freier, MC; Holshouser, BA; Riggs, ML	1
Adamides, AA; Bye, N; Kossmann, T; Morganti-Kossmann, MC; Murray, L; Nguyen, P; Phillips, DJ; Rosenfeld, JV; Vallance, S	1
Gurevich, B; Maoz, I; Shapira, Y; Teichberg, VI; Tkachov, S; Zlotnik, A	1
Bandrowski, AE; Huguenard, JR; Parada, I; Prince, DA; Reimer, RJ; Tani, H; Wynn, M	1
Godfrey, DA; Godfrey, TG; Rubin, AM; Sun, Y	1
Benham, CD; Cater, HL; Davis, SM; Gitterman, D; Morrison, B; Sundstrom, LE	1
Bartnik, BL; Hovda, DA; Lee, PW	1
Bullock, R; Gilman, C; Kunene, N; Mazzeo, A; Samuelson, R; Young, HF	1
Hernández-Benítez, R; Pasantes-Morales, H; Ramos-Mandujano, G; Vázquez-Juárez, E	1
Beyer, TF; Dohse, NK; Griebenow, M; Mautes, A; Sakowitz, OW; Stover, JF; Stroop, R; Thomale, UW; Unterberg, AW	1
Andersson, C; Aneman, O; Dabrosin, C; Hillman, J; Mellergård, P; Persson, M	1
Hazell, AS	1
Chang, CP; Chio, CC; Kuo, JR; Lin, MT; Lo, CJ	1
Hamby, AM; Suh, SW; Swanson, RA	1
Bauer, C; Blackstone, K; Brady, M; Brown, L; Bryan, R; Busch, J; Leigh, A; Lema Tomé, CM; Miller, R; Nottingham, C; Smith, C; Turner, CP	1
Eisner, F; Engele, J; Lehmann, C	1
An, J; Chen, JF; Chen, X; Dai, S; Li, P; Li, W; Liu, P; Liu, X; Wang, H; Xiong, R; Zhao, Y; Zhou, Y; Zhu, M; Zhu, P	1
Groenendaal, F; Heijnen, CJ; Kavelaars, A; Nijboer, CH; van Bel, F; Vroon, A	1
Belli, A; Kitchen, N; Petzold, A; Russo, S; Sen, J; Smith, M	1
Dai, SS; Li, W; Xiong, RP; Yang, N; Zhou, YG; Zhu, PF	1
Baker, AJ; Bell, JD; Park, E	1
McAdoo, DJ; Wu, P	1
Gluckman, P; Gunn, A; Johnston, B; Mallard, C; Marks, K; Tan, W; Williams, C	1
Hama, T; Hatanaka, H; Ishiguro, M; Kubota, M; Maruyama, M; Murayama, M; Ogura, A; Omori, A; Sato, K; Sekiguchi, M	1
Botscheller, ML; DeKosky, ST; Marion, DW; Palmer, AM; Styren, SD; Swedlow, PE	1
Alonso, O; Busto, R; Dietrich, WD; Ginsberg, MD; Globus, MY	1
Kanthan, R; Shuaib, A	1
Zornow, MH	1
Carlson, E; Chan, PH; Chen, SF; Epstein, CJ; Gafni, J; Imaizumi, S; Kamii, H; Kinouchi, H; Yang, G	1
Bullock, R; Rafferty, C; Stewart, L; Teasdale, GM	1
Bullock, R	1
Botscheller, ML; Marion, DW; Palmer, AM; Redd, EE	1
Bullock, R; Fujisawa, H; Landholt, H; Maxwell, WL	1
Inao, S; Kuchiwaki, H; Sugita, K; Yamamoto, M; Yoshida, K	1
Kempski, OS; Volk, C	1
Bonne, C; Cazevieille, C; Meynier, F; Muller, A	1
Anderson, DK; Kim-Lee, MH; Stokes, BT	1
Baker, AJ; MacMillan, VH; Moulton, RJ; Shedden, PM	1
Araujo, M; Wandosell, F	1
Holaday, NJ; Jeevanandam, M; Lubhan, CL; Petersen, SR	1
Hama, T; Kato, R; Murayama, M; Ohtake, A; Sato, K	1
Hagberg, H; Puka-Sundvall, M; Sandberg, M	1
Hori, S; Ichihara, N; Iwama, H; Kawashima, N; Kikuchi, T; Manabe, T; Nishikawa, T; Okuyama, S; Takahashi, K; Takimoto, M; Tanaka, K; Wada, K; Watanabe, M; Watase, K; Yamada, K	1
Brucklacher, RM; Vannucci, RC; Vannucci, SJ	1
Bertoni-Freddari, C; Meier-Ruge, WA	1
Obrenovitch, TP; Urenjak, J	1
Aggarwal, N; Baethmann, A; Eriskat, J; Plesnila, M; Stoffel, M	1
Blomstrand, F; Hansson, E; Khatibi, S; Olsson, T; Rönnbäck, L	1
Bittigau, P; Ikonomidou, C	1
Baker, AJ; Brown, JI; Konasiewicz, SJ; Moulton, RJ	1
Bashkatova, VG; Rayevsky, KS	1
Bullock, R; Choi, SC; Marmarou, A; Myseros, J; Ward, JD; Woodward, JJ; Young, HF; Zauner, A	1
March, PA	1
Bullock, R; Choi, S; Doppenberg, EM; Koura, SS; Marmarou, A; Young, HF	1
Keller, JN; Mattson, MP; Scheff, SW; Sullivan, PG	1
Becker, DP; Caron, M; Hovda, DA; Martin, NA; Prins, M; Ronne-Engstrom, E; Shalmon, E; Vespa, P	1
Alessandri, B; Bullock, R	1
Kempski, OS; Kossmann, T; Morganti-Kossmann, MC; Pleines, UE; Stocker, R; Stover, JF	1
Kempski, OS; Kossmann, T; Lenzlinger, PM; Morganti-Kosmann, MC; Stocker, R; Stover, JF	1
Bullock, R; Di, X; Gordon, J	1
Fujisawa, H; Ishikawa, T; Ito, H; Maekawa, T; Suehiro, E	1
Der, TC; Dikranian, K; Ikonomidou, C; Ishimaru, MJ; Olney, JW; Sesma, MA; Tenkova, TI	1
Bland, ST; Humm, JL; James, DC; Kozlowski, DA; Schallert, T	1
Kossmann, T; Morganti-Kossmann, MC; Pleines, UE; Stocker, R; Stover, JF	1
Hanley, DF; Varelas, P	1
Bullock, R; Doppenberg, E; Marmarou, A; Rossi, S; Stiefel, M; Yamamoto, T; Zauner, A	1
Alessandri, B; Bullock, R; Choi, S; Doppenberg, E; Koura, S; Woodward, J; Young, HF	1
Alessandri, B; Bullock, R; Choi, S; Doppenberg, E; Woodward, J; Zauner, A	1
Bullock, R; Doppenberg, EM; Massie, TS; Reinert, M; Zauner, A	1
Brown, SD; Letarte, PB; Marion, DW; Puccio, AM	1
Hutchinson, PJ; Maskell, LB; O'Connell, MT; Pickard, JD	1
Ellis, EF; Moore, SF; Rzigalinski, BA; Weber, JT; Willoughby, KA	1
Matsushita, Y; Nawashiro, H; Shima, K; Wada, K	1
Dohse, NK; Stover, JF; Unterberg, AW	1
Baab, PJ; Mena, FV; Zielke, CL; Zielke, HR	1
Beyer, TF; Schöning, B; Stover, JF; Unterberg, AW; Woiciechowsky, C	1
Al-Rawi, PG; Gupta, AK; Hutchinson, DB; Hutchinson, PJ; Kett-White, R; Kirkpatrick, PJ; Maskell, LB; O'Connell, MT; Pickard, JD; Richards, HK	1
Stover, JF; Unterberg, AW	1
Armstead, WM	1
Babcock, DJ; Choi, DW; Lee, JM; Zipfel, GJ	1
Bao, W; Faden, AI; Fan, L; Knoblach, SM; Movsesyan, VA; Mullins, PG; O'Leary, DM	1
Adelson, PD; Bell, MJ; Clark, RS; Graham, SH; Kochanek, PM; Marion, DW; Rose, ME; Ruppel, RA; Wisniewski, SR	1
Kroppenstedt, SN; Stover, JF; Unterberg, AW	1
Ellis, EF; Floyd, CL; Rzigalinski, BA; Sitterding, HA; Weber, JT; Willoughby, KA	1
Beyer, TF; Stover, JF; Unterberg, AW	1
Maas, AI	1
Bao, F; Gutierrez, E; Haglid, K; Hamberger, A; Hansson, HA; Huang, Y; Runnerstam, M; Shi, J; Viano, D	1
Sakowitz, OW; Schöning, B; Stover, JF; Unterberg, AW; Woiciechowsky, C	1
Gratzl, O; Langemann, H; Mendelowitsch, A; Ritz, MF; Ros, J	1
Ishida, A; Johnston, MV; Nakajima, W; Trescher, WH	1
Katoh, H; Matsushita, Y; Nawashiro, H; Shima, K	1
Goodman, JC; Gopinath, SP; Robertson, CS; Valadka, AB	1
al-Rawi, PG; Gupta, AK; Hutchinson, DB; Hutchinson, PJ; Kirkpatrick, PJ; Maskell, LB; O'Connell, MT; Pickard, JD	1
Bullock, R; Doppenberg, E; Hoelper, B; Reinert, M; Zauner, A	1
Bullock, R; Clausen, T; Levasseur, JE; Rice, AC; Zauner, A	1
Autere, AM; Kaila, K; Lahtinen, H; Lauri, SE; Paalasmaa, P	1
Bechmann, I; Brück, W; Bührer, C; Stover, JF; Unterberg, A; van Landeghem, FK; von Deimling, A	1
Achaval, M; Alves, LB; Chemale, I; Costa, MS; Emanuelli, T; Friedman, G; Leal, L; Regner, A	1
Nordström, CH; Ståhl, N; Ungerstedt, U	1
Alessandri, B; Fillenz, M; Landolt, H; Pecinska, N; Ros, J	1
Ikegaya, Y; Matsuki, N; Matsuura, S; Nishiyama, N; Yamada, MK	1
Barcsay, E; Kunze, E; Meixensberger, J; Roosen, K; Vaeth, A	1
Feng, D; Luo, Z; Yue, S	1
Adelson, PD; Bell, MJ; Carcillo, JA; Clark, RS; Graham, SH; Jackson, EK; Janesko, KL; Kochanek, PM; Marion, DW; Mi, Z; Robertson, CL; Ruppel, RA; Wisniewski, SR	1
Cengiz, P; Zimmerman, JJ	1
Alvarez-Sabín, J; Castillo, J; Dávalos, A; Kase, CS; Leira, R; Montaner, J; Pumar, JM; Silva, Y	1
Bullock, R; Doppenberg, EM; Gilman, C; Menzel, M; Soukup, J; Young, HF; Zauner, A	1
Doi, M; Kubo, Y; Kudo, A; Ogasawara, K; Ogawa, A; Sugawara, A; Suzuki, M; Suzuki, T; Yoshida, K	1
Aigbirhio, FI; Al-Rawi, PG; Chatfield, DA; Clark, JC; Coles, JP; Fryer, TF; Gupta, AK; Hutchinson, PJ; Kett-White, R; Kirkpatrick, PJ; Menon, DK; Minhas, PS; O'Connell, MT; Pickard, JD	1
Graham, SH; Huerbin, MB; Kochanek, PM; Marion, DW; Melick, J; Palmer, AM; Rose, ME; Schiding, JK	1
Bullock, MR; Chiueh, CC; Khaldi, A; Woodward, JJ	1
Faden, AI; Panter, SS	1
Bullock, R; Kuroda, Y; McCulloch, J; Teasdale, GM	1
Baethmann, A; Kempski, O; Schürer, L; von Andrian, U	1
Olney, JW	1
Chang, C; Ikeda, J; Joó, F; Kawai, K; Lohr, J; Mies, G; Nagashima, G; Nowak, TS; Ruetzler, C; Saito, N	1
Demediuk, P; Faden, AI; Panter, SS; Vink, R	1
Barron, KD; Cragoe, EJ; Kimelberg, HK; Rose, JW; Waniewski, RA	1
Baethmann, A; Kempski, O; Maier-Hauff, K; Schürer, L; Unterberg, A; Wahl, M	1
Becker, DP; Cheung, M; Povlishock, J; Verity, MA	1

Reviews

61 review(s) available for glutamic acid and Brain Injuries

Article	Year
Recent Investigations on Neurotransmitters' Role in Acute White Matter Injury of Perinatal Glia and Pharmacotherapies-Glia Dynamics in Stem Cell Therapy. Molecular neurobiology, 2022, Volume: 59, Issue:4 Topics: Brain Injuries; Cell- and Tissue-Based Therapy; Cerebral Palsy; Glutamic Acid; Humans; Infant; Infant, Newborn; Leukomalacia, Periventricular; Neuroglia; Neurotransmitter Agents; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; White Matter	2022
Roles of glutamate in brain injuries after subarachnoid hemorrhage. Histology and histopathology, 2022, Volume: 37, Issue:11 Topics: Brain Injuries; Glutamic Acid; Humans; Microcirculation; Subarachnoid Hemorrhage; Vasospasm, Intracranial	2022
Glutamate Neurotoxicity and Destruction of the Blood-Brain Barrier: Key Pathways for the Development of Neuropsychiatric Consequences of TBI and Their Potential Treatment Strategies. International journal of molecular sciences, 2022, Aug-25, Volume: 23, Issue:17 Topics: Blood-Brain Barrier; Brain; Brain Injuries; Brain Injuries, Traumatic; Glutamic Acid; Humans; Neurotoxicity Syndromes	2022
Neonatal Hypoglycemia and Brain Vulnerability. Frontiers in endocrinology, 2021, Volume: 12 Topics: Brain; Brain Injuries; Cell Death; Epilepsy; Glucose; Glutamic Acid; Homeostasis; Humans; Hypoglycemia; Infant, Newborn; Infant, Newborn, Diseases; Neurons; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Receptors, Glutamate; Risk Factors; Zinc	2021
GLT-1 Upregulation as a Potential Therapeutic Target for Ischemic Brain Injury. Current pharmaceutical design, 2017, Volume: 23, Issue:33 Topics: Animals; Brain Injuries; Brain Ischemia; Drug Delivery Systems; Estrogen Receptor Modulators; Excitatory Amino Acid Transporter 2; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Histamine Antagonists; Humans; Up-Regulation	2017
Mechanisms of Endogenous Neuroprotective Effects of Astrocytes in Brain Injury. Oxidative medicine and cellular longevity, 2018, Volume: 2018 Topics: Animals; Antioxidants; Astrocytes; Brain Injuries; Central Nervous System; Glutamic Acid; Iron; Mitochondria; NF-E2-Related Factor 2; Oxidative Stress	2018
Pathophysiology of neurodegeneration following traumatic brain injury. The West Indian medical journal, 2012, Volume: 61, Issue:7 Topics: Brain Injuries; Cell Death; Excitatory Amino Acids; Glutamic Acid; Humans; Inflammation; Nerve Degeneration; Oxidative Stress	2012
Lactate shuttling and lactate use as fuel after traumatic brain injury: metabolic considerations. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:11 Topics: Animals; Brain Injuries; Brain Ischemia; Glutamic Acid; Humans; Lactic Acid; Mitochondria; Oxidation-Reduction; Pyruvic Acid	2014
Common biochemical defects linkage between post-traumatic stress disorders, mild traumatic brain injury (TBI) and penetrating TBI. Brain research, 2015, Mar-02, Volume: 1599 Topics: Animals; Brain; Brain Injuries; Glutamic Acid; Head Injuries, Penetrating; Humans; Neuroimmunomodulation; Oxidative Stress; Stress Disorders, Post-Traumatic	2015
Glutamate and GABA imbalance following traumatic brain injury. Current neurology and neuroscience reports, 2015, Volume: 15, Issue:5 Topics: Animals; Brain Injuries; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Homeostasis; Humans; Receptors, GABA; Receptors, Glutamate	2015
Excitotoxicity as a Common Mechanism for Fetal Neuronal Injury with Hypoxia and Intrauterine Inflammation. Advances in pharmacology (San Diego, Calif.), 2016, Volume: 76 Topics: Animals; Brain Injuries; Female; Glutamic Acid; Humans; Hypoxia; Hypoxia-Ischemia, Brain; Inflammation; Pregnancy	2016
Posttraumatic epilepsy: hemorrhage, free radicals and the molecular regulation of glutamate. Neurochemical research, 2009, Volume: 34, Issue:4 Topics: Animals; Antioxidants; Brain Injuries; Disease Models, Animal; Epilepsy; Free Radicals; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Intracranial Hemorrhages; Neurons; Neuropil; Nitric Oxide; Oxidation-Reduction	2009
Drug targets for traumatic brain injury from poly(ADP-ribose)polymerase pathway modulation. British journal of pharmacology, 2009, Volume: 157, Issue:5 Topics: Animals; Brain Injuries; Cell Death; Disease Models, Animal; Drug Design; Enzyme Inhibitors; Glutamic Acid; Humans; Mice; Mice, Knockout; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Receptors, N-Methyl-D-Aspartate; Signal Transduction	2009
Actions of estrogens on glial cells: Implications for neuroprotection. Biochimica et biophysica acta, 2010, Volume: 1800, Issue:10 Topics: Animals; Astrocytes; Brain Edema; Brain Injuries; Cell Survival; Estrogens; Glutamic Acid; Humans; Inflammation; Intercellular Signaling Peptides and Proteins; Microglia; Myelin Sheath; Neurons; Neuroprotective Agents; Oligodendroglia	2010
Clinical characteristics and pathophysiological mechanisms of focal and diffuse traumatic brain injury. Journal of cellular and molecular medicine, 2010, Volume: 14, Issue:10 Topics: Brain Edema; Brain Injuries; Calpain; Caspases; Diffuse Axonal Injury; Excitatory Amino Acids; Glasgow Coma Scale; Glutamic Acid; Humans; Injury Severity Score; Magnetic Resonance Imaging; Mitochondria; Necrosis; Neurotransmitter Agents	2010
[Use of intracerebral microdialysis in severe traumatic brain injury]. No shinkei geka. Neurological surgery, 2010, Volume: 38, Issue:9 Topics: Adult; Aged; Animals; Brain Chemistry; Brain Injuries; Brain Ischemia; Glucose; Glutamic Acid; Glycerol; Humans; Lactates; Male; Microdialysis; Middle Aged; Pyruvic Acid	2010
The developing oligodendrocyte: key cellular target in brain injury in the premature infant. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2011, Volume: 29, Issue:4 Topics: Animals; Brain Injuries; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Immunity, Innate; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Leukomalacia, Periventricular; Microglia; Oligodendroglia; Reactive Oxygen Species	2011
Adult neurogenesis is regulated by endogenous factors produced during neurodegeneration. Journal of pharmacological sciences, 2011, Volume: 115, Issue:4 Topics: Animals; Biomarkers; Brain; Brain Injuries; Cytokines; Glutamic Acid; Humans; Nerve Degeneration; Neurodegenerative Diseases; Neurogenesis; Reactive Oxygen Species; Stroke	2011
The role of glutamate receptors in traumatic brain injury: implications for postsynaptic density in pathophysiology. Brain research bulletin, 2011, Jul-15, Volume: 85, Issue:6 Topics: Brain Injuries; Glutamic Acid; Humans; Nerve Tissue Proteins; Post-Synaptic Density; Receptors, Glutamate; Signal Transduction	2011
[Cerebral microdialysis in the current clinical setting]. Medicina intensiva, 2012, Volume: 36, Issue:3 Topics: Animals; Brain Chemistry; Brain Damage, Chronic; Brain Injuries; Cerebrovascular Disorders; Critical Care; Energy Metabolism; Glucose; Glutamic Acid; Glycerol; Humans; Hypoxia, Brain; Lactates; Microdialysis; Monitoring, Physiologic; Prognosis; Pyruvates	2012
The role of glutamate in neuronal ischemic injury: the role of spark in fire. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2012, Volume: 33, Issue:2 Topics: Animals; Brain Injuries; Cell Death; Glutamic Acid; Humans; Ischemia; Neurons; Reactive Oxygen Species; Receptors, Glutamate	2012
Is there a role for vagus nerve stimulation therapy as a treatment of traumatic brain injury? British journal of neurosurgery, 2012, Volume: 26, Issue:3 Topics: Animals; Brain Injuries; Encephalitis; Glutamic Acid; Hippocampus; Humans; Intracranial Hypertension; Neural Stem Cells; Neuronal Plasticity; Norepinephrine; Rats; Synapses; Vagus Nerve Stimulation	2012
Sex and steroid hormones in early brain injury. Reviews in endocrine & metabolic disorders, 2012, Volume: 13, Issue:3 Topics: Animals; Brain; Brain Injuries; Estradiol; Female; Glutamic Acid; Gonadal Steroid Hormones; Hippocampus; Humans; Hypoxia-Ischemia, Brain; Male; Models, Animal; Neuroprotective Agents; Receptors, GABA-A; Sex Characteristics; Testosterone	2012
Understanding secondary injury. The Quarterly review of biology, 2012, Volume: 87, Issue:2 Topics: Apoptosis; Brain Injuries; Calcium Channels; Cell Death; Edema; Glutamic Acid; Hemorrhage; Humans; Ischemia; Lipid Peroxidation; Neurons; Reperfusion Injury; Sodium Channels; Spinal Cord Injuries; Stroke; Trauma, Nervous System; Wounds and Injuries; Zinc	2012
Pharmacology of traumatic brain injury. Current opinion in pharmacology, 2003, Volume: 3, Issue:1 Topics: Animals; Brain Injuries; Cannabinoids; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans	2003
Astrocytes and brain injury. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2003, Volume: 23, Issue:2 Topics: Animals; Astrocytes; Blood-Brain Barrier; Brain Edema; Brain Injuries; Cell Survival; Extracellular Space; Gap Junctions; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Nerve Regeneration; Neurites; Potassium; Reactive Oxygen Species	2003
Excitatory amino acid neurotoxicity. Advances in experimental medicine and biology, 2002, Volume: 513 Topics: Animals; Aspartic Acid; Brain; Brain Injuries; Brain Ischemia; Calcium; Epilepsy; Glutamic Acid; Humans; Mitochondria; Nervous System Diseases; Neurodegenerative Diseases; Reactive Nitrogen Species; Reactive Oxygen Species; Receptors, Glutamate; Signal Transduction	2002
[Glutamate in traumatic brain injuries]. Neuro-Chirurgie, 2003, Volume: 49, Issue:2-3 Pt 1 Topics: Brain Injuries; Glutamic Acid; Humans; Neurotransmitter Agents; Receptors, Glutamate	2003
Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury? The Lancet. Neurology, 2002, Volume: 1, Issue:6 Topics: Brain Injuries; Clinical Trials as Topic; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Receptors, N-Methyl-D-Aspartate; Stroke; Treatment Failure	2002
White matter injury mechanisms. Current molecular medicine, 2004, Volume: 4, Issue:2 Topics: Adenosine Triphosphate; Animals; Axons; Biological Transport; Brain; Brain Injuries; Calcium; Cytosol; Glutamic Acid; Humans; Hypoxia; Ions; Microscopy, Confocal; Models, Biological; Muscles; Optic Nerve; Rats; Sodium; Sodium-Potassium-Exchanging ATPase; Spinal Cord Injuries; Time Factors	2004
Astrocyte mitochondrial mechanisms of ischemic brain injury and neuroprotection. Neurochemical research, 2004, Volume: 29, Issue:3 Topics: Animals; Apoptosis; Astrocytes; Brain Injuries; Brain Ischemia; Glutamic Acid; Glutathione; Humans; Mitochondria; Models, Neurological; Neurons; Reperfusion	2004
Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury. Cellular and molecular life sciences : CMLS, 2004, Volume: 61, Issue:6 Topics: Animals; Brain Injuries; Brain Ischemia; Glutamic Acid; Humans; N-Methylaspartate; Nerve Degeneration; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate	2004
What is the optimal threshold for cerebral perfusion pressure following traumatic brain injury? Neurosurgical focus, 2003, Dec-15, Volume: 15, Issue:6 Topics: Blood Pressure; Brain Injuries; Brain Ischemia; Cerebrovascular Circulation; Coma; Critical Care; Fluid Therapy; Glutamic Acid; Humans; Hypoxia, Brain; Intracranial Hypertension; Intracranial Hypotension; Intracranial Pressure; Microdialysis; Monitoring, Physiologic; Oximetry; Positron-Emission Tomography; Randomized Controlled Trials as Topic; Respiratory Distress Syndrome; Ultrasonography, Doppler, Transcranial	2003
Consensus meeting on microdialysis in neurointensive care. Intensive care medicine, 2004, Volume: 30, Issue:12 Topics: Brain Injuries; Brain Ischemia; Critical Care; Glutamic Acid; Humans; Injury Severity Score; Intracranial Pressure; Lactates; Microdialysis; Subarachnoid Hemorrhage; Sweden	2004
Pathophysiology of traumatic injury in the developing brain: an introduction and short update. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2004, Volume: 56, Issue:1-2 Topics: Age Factors; Biomechanical Phenomena; Brain Edema; Brain Injuries; Cerebrovascular Circulation; Child, Preschool; Dopamine; Glutamic Acid; Humans; Infant; Infant, Newborn; Oxidative Stress; Synaptic Transmission	2004
Excitotoxicity in perinatal brain injury. Brain pathology (Zurich, Switzerland), 2005, Volume: 15, Issue:3 Topics: Age Factors; Animals; Brain Injuries; Calcium; Cell Death; Glutamic Acid; Humans; Infant, Newborn; Models, Neurological; Neurotoxins; Receptors, Glutamate; Sex Factors	2005
Glutamate-mediated glial injury: mechanisms and clinical importance. Glia, 2006, Jan-15, Volume: 53, Issue:2 Topics: Amino Acid Transport System X-AG; Animals; Brain Injuries; Brain Ischemia; Glutamic Acid; Humans; Multiple Sclerosis; Nervous System Diseases; Neurodegenerative Diseases; Neuroglia; Receptors, Glutamate; Signal Transduction	2006
Excitotoxic mechanisms and the role of astrocytic glutamate transporters in traumatic brain injury. Neurochemistry international, 2006, Volume: 48, Issue:5 Topics: Amino Acid Transport System X-AG; Animals; Astrocytes; Brain; Brain Injuries; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamic Acid; Humans; Neurotoxins; Receptors, Glutamate	2006
Pharmacotherapy of posttraumatic cognitive impairments. Behavioural neurology, 2006, Volume: 17, Issue:1 Topics: Adrenergic Agents; Biogenic Amines; Brain Injuries; Central Nervous System Stimulants; Cholinesterase Inhibitors; Cognition Disorders; Dopamine Agents; Glutamic Acid; Humans; Neurotransmitter Agents	2006
Erratum to "Cellular mechanisms underlying acquired epilepsy: the calcium hypothesis of the induction and maintenance of epilepsy." [Pharmacol. Ther. 105(3) (2005) 229-266]. Pharmacology & therapeutics, 2006, Volume: 111, Issue:1 Topics: Animals; Anticonvulsants; Brain Injuries; Calcium; Epilepsy; Glutamic Acid; Homeostasis; Humans	2006
Functional changes in astroglial cells in epilepsy. Glia, 2006, Volume: 54, Issue:5 Topics: Animals; Aquaporins; Astrocytes; Brain; Brain Injuries; Epilepsy; Glutamic Acid; Humans; Neoplasms; Potassium Channels; Tuberous Sclerosis; Vesicular Glutamate Transport Proteins	2006
Excitotoxic mechanisms in stroke: an update of concepts and treatment strategies. Neurochemistry international, 2007, Volume: 50, Issue:7-8 Topics: Amino Acid Transport System X-AG; Astrocytes; Brain Edema; Brain Injuries; Cerebral Hemorrhage; Glutamic Acid; Humans; Middle Cerebral Artery; Neurotransmitter Agents; Oxidative Stress; Receptors, Glutamate; Stroke	2007
Hypoglycemia, brain energetics, and hypoglycemic neuronal death. Glia, 2007, Volume: 55, Issue:12 Topics: Adenosine; Animals; Brain Chemistry; Brain Injuries; Cell Death; Energy Metabolism; Glutamic Acid; Humans; Hypoglycemia; Neurons; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species	2007
Traumatic brain injury: can the consequences be stopped? CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2008, Apr-22, Volume: 178, Issue:9 Topics: Animals; Axons; Biomarkers; Brain Edema; Brain Injuries; Calcium; Calpain; Diffuse Axonal Injury; Glutamic Acid; Humans; Intracranial Hypertension; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate	2008
Microdialysis in central nervous system disorders and their treatment. Pharmacology, biochemistry, and behavior, 2008, Volume: 90, Issue:2 Topics: Animals; Brain Injuries; Calibration; Central Nervous System Diseases; Glutamic Acid; Hydroxyl Radical; Microdialysis; Neurons; Pain; Reactive Oxygen Species; Spinal Cord Injuries; Zinc	2008
Inhibition of glutamate release: a possible mechanism of hypothermic neuroprotection. Journal of neurosurgical anesthesiology, 1995, Volume: 7, Issue:2 Topics: Brain; Brain Injuries; Brain Ischemia; Glutamic Acid; Humans; Hyperthermia, Induced; Treatment Outcome	1995
Neuron-glial interaction during injury and edema of the CNS. Acta neurochirurgica. Supplementum, 1994, Volume: 60 Topics: Acid-Base Equilibrium; Animals; Brain; Brain Edema; Brain Injuries; Brain Ischemia; Cell Communication; Cell Survival; Glutamic Acid; Humans; In Vitro Techniques; Neuroglia; Neurons; Water-Electrolyte Balance	1994
Pathogenesis of decreased glucose turnover and oxidative phosphorylation in ischemic and trauma-induced dementia of the Alzheimer type. Annals of the New York Academy of Sciences, 1997, Sep-26, Volume: 826 Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Brain Injuries; Brain Ischemia; Glucose; Glutamic Acid; Heat Stroke; Humans; Mitochondria; Oxidative Phosphorylation	1997
Is high extracellular glutamate the key to excitotoxicity in traumatic brain injury? Journal of neurotrauma, 1997, Volume: 14, Issue:10 Topics: Animals; Brain Injuries; Extracellular Space; Glutamic Acid; Humans; Neurotoxins	1997
Glutamate in neurologic diseases. Journal of child neurology, 1997, Volume: 12, Issue:8 Topics: Acute Disease; Animals; Brain Injuries; Brain Ischemia; Child; Child Development; Chronic Disease; Disease Models, Animal; Epilepsy; Glutamic Acid; Humans; Nervous System Diseases; Neurodegenerative Diseases; Neuroprotective Agents; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate	1997
Seizures: classification, etiologies, and pathophysiology. Clinical techniques in small animal practice, 1998, Volume: 13, Issue:3 Topics: Animals; Brain Injuries; Cat Diseases; Cats; Cerebral Cortex; Dog Diseases; Dogs; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Neurons; Seizures; Synapses	1998
Glutamate and its receptors in the pathophysiology of brain and spinal cord injuries. Progress in brain research, 1998, Volume: 116 Topics: Animals; Brain Injuries; Glutamic Acid; Humans; Receptors, Glutamate; Spinal Cord Injuries	1998
Glutamate in parenteral nutrition. Critical care medicine, 1999, Volume: 27, Issue:10 Topics: Animals; Blood-Brain Barrier; Brain Injuries; Critical Illness; Glutamic Acid; Humans; Intensive Care Units; Parenteral Nutrition	1999
Neuronal apoptosis after CNS injury: the roles of glutamate and calcium. Journal of neurotrauma, 2000, Volume: 17, Issue:10 Topics: Animals; Apoptosis; Brain Injuries; Brain Ischemia; Calcium; Calcium Signaling; Glutamic Acid; Humans; Necrosis; Nerve Degeneration; Neuroprotective Agents; Neurotoxins	2000
Neuroprotective agents in traumatic brain injury. Expert opinion on investigational drugs, 2001, Volume: 10, Issue:4 Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Brain Injuries; Calcium; Clinical Trials as Topic; Free Radicals; Genetic Therapy; Glutamic Acid; Humans; Lipid Peroxidation; Neuroprotective Agents; Nitric Oxide	2001
Neurobiology of hypoxic-ischemic injury in the developing brain. Pediatric research, 2001, Volume: 49, Issue:6 Topics: Animals; Apoptosis; Brain; Brain Injuries; Brain Ischemia; Cerebral Palsy; Fetal Hypoxia; Glucose; Glutamic Acid; Humans; Hypoxia, Brain; Mitochondria; Nerve Degeneration	2001
The significance of nitric oxide production in the brain after injury. Annals of the New York Academy of Sciences, 2002, Volume: 962 Topics: Brain Injuries; Cell Line; Glutamic Acid; Humans; Microdialysis; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Transfection	2002
Prevention of post-traumatic excitotoxic brain damage with NMDA antagonist drugs: a new strategy for the nineties. Acta neurochirurgica. Supplementum, 1992, Volume: 55 Topics: Animals; Brain Damage, Chronic; Brain Injuries; Brain Ischemia; Central Nervous System Agents; Dizocilpine Maleate; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Humans; Receptors, N-Methyl-D-Aspartate; Retrograde Degeneration	1992
Excitotoxin-mediated neuron death in youth and old age. Progress in brain research, 1990, Volume: 86 Topics: Aging; Alzheimer Disease; Amino Acids; Animals; Aspartic Acid; Brain Diseases, Metabolic; Brain Injuries; Calcium Channels; Cell Survival; Central Nervous System; Central Nervous System Diseases; Food; Food Additives; Glutamates; Glutamic Acid; Humans; Ion Channel Gating; Neurons; Neurotoxins; Rats; Receptors, N-Methyl-D-Aspartate	1990
Mediators of brain edema and secondary brain damage. Critical care medicine, 1988, Volume: 16, Issue:10 Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood-Brain Barrier; Brain; Brain Edema; Brain Injuries; Glutamates; Glutamic Acid; Humans; Kallikreins; Kinins	1988
Brain cellular injury and recovery--horizons for improving medical therapies in stroke and trauma. The Western journal of medicine, 1988, Volume: 148, Issue:6 Topics: Adult; Animals; Axons; Brain Concussion; Brain Injuries; Cats; Cerebrovascular Disorders; Glutamates; Glutamic Acid; Humans; Male	1988

Trials

13 trial(s) available for glutamic acid and Brain Injuries

Article	Year
Plasma glutamate-modulated interaction of A2AR and mGluR5 on BMDCs aggravates traumatic brain injury-induced acute lung injury. The Journal of experimental medicine, 2013, Apr-08, Volume: 210, Issue:4 Topics: Acute Lung Injury; Adenosine; Adenosine A2 Receptor Agonists; Adult; Animals; Bone Marrow Cells; Brain Injuries; Disease Models, Animal; Female; Glutamic Acid; Humans; Male; Mice; Mice, Knockout; Middle Aged; Phenethylamines; Protein Kinase C; Receptor, Adenosine A2A; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Signal Transduction; Triazines; Triazoles; Type C Phospholipases	2013
Prolonged continuous intravenous infusion of the dipeptide L-alanine- L-glutamine significantly increases plasma glutamine and alanine without elevating brain glutamate in patients with severe traumatic brain injury. Critical care (London, England), 2014, Jul-02, Volume: 18, Issue:4 Topics: Adolescent; Adult; Alanine; Brain Injuries; Dipeptides; Female; Glutamic Acid; Glutamine; Humans; Infusions, Intravenous; Male; Middle Aged; Severity of Illness Index; Young Adult	2014
Cerebral microdialysis effects of propofol versus midazolam in severe traumatic brain injury. Journal of neurotrauma, 2012, Apr-10, Volume: 29, Issue:6 Topics: Adult; Biomarkers; Brain Chemistry; Brain Injuries; Cerebral Cortex; Female; Glucose; Glutamic Acid; Glycerol; Humans; Hypnotics and Sedatives; Lactic Acid; Male; Microdialysis; Midazolam; Neuroprotective Agents; Propofol; Pyruvic Acid; Single-Blind Method	2012
A microdialysis study of oral vigabatrin administration in head injury patients: preliminary evaluation of multimodality monitoring. Acta neurochirurgica. Supplement, 2012, Volume: 114 Topics: Administration, Oral; Adolescent; Adult; Aged; Amino Acids; Anticonvulsants; Blood Pressure; Brain Chemistry; Brain Injuries; Chromatography, High Pressure Liquid; Female; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Humans; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Time Factors; Vigabatrin; Young Adult	2012
Effect of hyperventilation on extracellular concentrations of glutamate, lactate, pyruvate, and local cerebral blood flow in patients with severe traumatic brain injury. Critical care medicine, 2002, Volume: 30, Issue:12 Topics: Adult; Brain; Brain Injuries; Brain Ischemia; Female; Glutamic Acid; Humans; Hyperventilation; Lactic Acid; Male; Microdialysis; Prospective Studies; Pyruvic Acid; Regional Blood Flow; Respiration, Artificial; Time Factors	2002
Evaluation of topiramate neuroprotective effect in severe TBI using microdialysis. Annals of the New York Academy of Sciences, 2003, Volume: 993 Topics: Blood-Brain Barrier; Brain Injuries; Fructose; Glutamic Acid; Humans; Microdialysis; Neuroprotective Agents; Time Factors; Topiramate	2003
Relationships between cerebrospinal fluid markers of excitotoxicity, ischemia, and oxidative damage after severe TBI: the impact of gender, age, and hypothermia. Journal of neurotrauma, 2004, Volume: 21, Issue:2 Topics: Adult; Age Factors; Biomarkers; Brain Injuries; Brain Ischemia; F2-Isoprostanes; Female; Glutamic Acid; Humans; Hypothermia, Induced; Lactic Acid; Male; Multivariate Analysis; Neurotoxins; Oxidative Stress; Sex Factors	2004
Continuous monitoring of jugular bulb oxygen saturation and the effect of drugs acting on cerebral metabolism. Acta neurochirurgica. Supplementum, 1993, Volume: 59 Topics: Adolescent; Adult; Aged; Brain; Brain Injuries; Child; Child, Preschool; Dose-Response Relationship, Drug; Energy Metabolism; Excitatory Amino Acid Antagonists; Female; Follow-Up Studies; Glutamic Acid; Hemodynamics; Humans; Infusions, Intravenous; Intracranial Pressure; Male; Middle Aged; Monitoring, Physiologic; Neurologic Examination; Oximetry; Oxygen Consumption; Propofol	1993
Clinical significance of CSF glutamate concentrations following severe traumatic brain injury in humans. Journal of neurotrauma, 1998, Volume: 15, Issue:4 Topics: Adult; Brain Injuries; Data Interpretation, Statistical; Electrophysiology; Evoked Potentials, Somatosensory; Female; Glutamic Acid; Humans; Male; Middle Aged; Treatment Outcome	1998
Thiopental and midazolam do not seem to impede metabolism of glutamate in brain-injured patients. Psychopharmacology, 1999, Volume: 141, Issue:1 Topics: Adolescent; Adult; Aged; Alanine; Brain Injuries; Cerebral Ventricles; Glutamic Acid; Glutamine; Humans; Hypnotics and Sedatives; Lactates; Midazolam; Middle Aged; Serine; Thiopental	1999
Thiopental attenuates energetic impairment but fails to normalize cerebrospinal fluid glutamate in brain-injured patients. Critical care medicine, 1999, Volume: 27, Issue:7 Topics: Adolescent; Adult; Biomarkers; Brain Injuries; Electroencephalography; Female; Glutamic Acid; Humans; Hypnotics and Sedatives; Hypoxanthine; Intracranial Hypertension; Intracranial Pressure; Lactic Acid; Male; Middle Aged; Prospective Studies; Statistics, Nonparametric; Thiopental	1999
High level of extracellular potassium and its correlates after severe head injury: relationship to high intracranial pressure. Journal of neurosurgery, 2000, Volume: 93, Issue:5 Topics: Adolescent; Adult; Brain; Brain Chemistry; Brain Injuries; Cerebrovascular Circulation; Extracellular Space; Glasgow Coma Scale; Glutamic Acid; Humans; Intracranial Pressure; Lactic Acid; Microdialysis; Monitoring, Physiologic; Potassium; Treatment Outcome	2000
Clinical cerebral microdialysis: brain metabolism and brain tissue oxygenation after acute brain injury. Neurological research, 2001, Volume: 23, Issue:8 Topics: Adolescent; Adult; Brain; Brain Injuries; Critical Care; Female; Glucose; Glutamic Acid; Humans; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Oxygen; Pyruvic Acid	2001

Other Studies

242 other study(ies) available for glutamic acid and Brain Injuries

Article	Year
Tongmai granules improve rat hippocampal injury by regulating TLR4/MyD88/AP-1 signaling pathway. Journal of ethnopharmacology, 2022, Mar-01, Volume: 285 Topics: Animals; Brain Injuries; Drugs, Chinese Herbal; Gene Expression Regulation; Glutamic Acid; Hippocampus; Male; Myeloid Differentiation Factor 88; Phytotherapy; Rats; Rats, Wistar; Toll-Like Receptor 4; Transcription Factor AP-1	2022
Questioning Glutamate Excitotoxicity in Acute Brain Damage: The Importance of Spreading Depolarization. Neurocritical care, 2022, Volume: 37, Issue:Suppl 1 Topics: Brain; Brain Injuries; Brain Ischemia; Cortical Spreading Depression; Glutamic Acid; Humans; Ischemia	2022
Cardiopulmonary Resuscitation May Not Stop Glutamate Release in the Cerebral Cortex. Journal of neurosurgical anesthesiology, 2023, Jul-01, Volume: 35, Issue:3 Topics: Animals; Brain Injuries; Cardiopulmonary Resuscitation; Cerebral Cortex; Glutamic Acid; Heart Arrest; Hypothermia; Rats; Rats, Sprague-Dawley	2023
Depolarization time and extracellular glutamate levels aggravate ultraearly brain injury after subarachnoid hemorrhage. Scientific reports, 2022, 06-17, Volume: 12, Issue:1 Topics: Animals; Brain; Brain Injuries; Glutamic Acid; Hypothermia; Rats; Rats, Sprague-Dawley; Subarachnoid Hemorrhage	2022
TRIOL Inhibits Rapid Intracellular Acidification and Cerebral Ischemic Injury: The Role of Glutamate in Neuronal Metabolic Reprogramming. ACS chemical neuroscience, 2022, 07-20, Volume: 13, Issue:14 Topics: AMP-Activated Protein Kinases; Brain Injuries; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Ischemic Stroke; Lactates; Neurons; Neuroprotective Agents	2022
Erinacine A attenuates glutamate transporter 1 downregulation and protects against ischemic brain injury. Life sciences, 2022, Oct-01, Volume: 306 Topics: Animals; Astrocytes; Brain Injuries; Brain Ischemia; Diterpenes; Down-Regulation; Excitatory Amino Acid Transporter 2; Glucose; Glutamic Acid; Mice	2022
Ectoderm-derived frontal bone mesenchymal stem cells promote traumatic brain injury recovery by alleviating neuroinflammation and glutamate excitotoxicity partially via FGF1. Stem cell research & therapy, 2022, 07-26, Volume: 13, Issue:1 Topics: Animals; Brain Injuries; Brain Injuries, Traumatic; Ectoderm; Fibroblast Growth Factor 1; Frontal Bone; Glutamic Acid; Inflammation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Microglia; Neuroinflammatory Diseases; Osteogenesis	2022
[Activation of the adenosine A2A receptor at the acute stage of moderate traumatic brain injury enhances the neuroprotective effects of oxaloacetate]. Sheng li xue bao : [Acta physiologica Sinica], 2022, Aug-25, Volume: 74, Issue:4 Topics: Adenosine A2 Receptor Agonists; Adenosine Triphosphate; Animals; Brain Injuries; Brain Injuries, Traumatic; Glutamic Acid; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxaloacetic Acid; Receptor, Adenosine A2A; RNA, Messenger; Tumor Necrosis Factor-alpha; Water	2022
Obesity induces extracellular vesicle release from the endothelium as a contributor to brain damage after cerebral ischemia in rats. Nutritional neuroscience, 2023, Volume: 26, Issue:8 Topics: Animals; Astrocytes; Brain; Brain Injuries; Brain Ischemia; Cytokines; Endothelial Cells; Endothelium; Extracellular Vesicles; Glutamic Acid; Obesity; Rats	2023
[Long-term neurological outcomes in premature children with excitotoxic brain damage]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2022, Volume: 122, Issue:9. Vyp. 2 Topics: Antibodies; Brain; Brain Injuries; Child; Female; Glutamic Acid; Humans; Infant; Infant, Newborn; Infant, Premature; Lactates; N-Methylaspartate; Pregnancy; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate	2022
Severity of prematurity and age impact early postnatal development of GABA and glutamate systems. Cerebral cortex (New York, N.Y. : 1991), 2023, 06-08, Volume: 33, Issue:12 Topics: Brain Injuries; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Infant; Infant, Newborn; Infant, Premature; Magnetic Resonance Spectroscopy; Pregnancy; Premature Birth	2023
Suppression of NDRG2 alleviates brain injury after intracerebral hemorrhage through mitigating astrocyte-drived glutamate neurotoxicity via NF-κB/GLT1 signaling. Brain research, 2020, 02-15, Volume: 1729 Topics: Adaptor Proteins, Signal Transducing; Animals; Astrocytes; Brain Injuries; Cerebral Hemorrhage; Excitatory Amino Acid Transporter 2; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Signal Transduction	2020
TNF-α Pretreatment Improves the Survival and Function of Transplanted Human Neural Progenitor Cells Following Hypoxic-Ischemic Brain Injury. Cells, 2020, 05-11, Volume: 9, Issue:5 Topics: Animals; Baculoviral IAP Repeat-Containing 3 Protein; Behavior, Animal; Brain Injuries; Caspase 3; Cell Line; Cell Polarity; Cell Survival; Chemokine CX3CL1; Culture Media, Conditioned; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Mice, Inbred ICR; Microglia; Nerve Growth Factors; Neural Stem Cells; Neurons; Neuroprotection; Phenotype; Stress, Physiological; Tumor Necrosis Factor-alpha; Up-Regulation	2020
Silymarin sex-dependently improves cognitive functions and alters TNF-α, BDNF, and glutamate in the hippocampus of mice with mild traumatic brain injury. Life sciences, 2020, Sep-15, Volume: 257 Topics: Animals; Animals, Outbred Strains; Brain Concussion; Brain Injuries; Brain-Derived Neurotrophic Factor; Cognition; Cognitive Dysfunction; Disease Models, Animal; Female; Glutamic Acid; Hippocampus; Male; Maze Learning; Memory; Mice; Neuroprotective Agents; Oxidative Stress; Sex Factors; Silymarin; Tumor Necrosis Factor-alpha	2020
Mechanical Brain Injury Increases Cells' Production of Cystathionine β-Synthase and Glutamine Synthetase, but Reduces Pax2 Expression in the Telencephalon of Juvenile Chum Salmon, International journal of molecular sciences, 2021, Jan-28, Volume: 22, Issue:3 Topics: Adult Stem Cells; Animals; Brain Injuries; Brain Regeneration; Cell Differentiation; Cell Proliferation; Cystathionine beta-Synthase; Fish Proteins; Gene Expression Regulation; Glutamate-Ammonia Ligase; Glutamic Acid; Hedgehog Proteins; Hydrogen Sulfide; Neural Stem Cells; Neuroepithelial Cells; Neurogenesis; Neuroglia; Neurons; Oncorhynchus keta; PAX2 Transcription Factor; PAX6 Transcription Factor; Telencephalon	2021
Design, Optimization, and Structural Characterization of an Apoptosis-Inducing Factor Peptide Targeting Human Cyclophilin A to Inhibit Apoptosis Inducing Factor-Mediated Cell Death. Journal of medicinal chemistry, 2021, 08-12, Volume: 64, Issue:15 Topics: Animals; Apoptosis; Apoptosis Inducing Factor; Brain Injuries; Cell Death; Cell Survival; Cells, Cultured; Cyclophilin A; Dose-Response Relationship, Drug; Drug Design; Glutamic Acid; Humans; Mice; Molecular Structure; Structure-Activity Relationship	2021
Glutamate, Glutamine, GABA and Oxidative Products in the Pons Following Cortical Injury and Their Role in Motor Functional Recovery. Neurochemical research, 2021, Volume: 46, Issue:12 Topics: Animals; Brain Injuries; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Lipid Peroxidation; Male; Motor Cortex; Motor Disorders; Oxidative Stress; Pons; Rats; Rats, Wistar; Recovery of Function	2021
Enhanced astrocytic d-serine underlies synaptic damage after traumatic brain injury. The Journal of clinical investigation, 2017, Aug-01, Volume: 127, Issue:8 Topics: Animals; Astrocytes; Brain; Brain Injuries; Brain Injuries, Traumatic; Cells, Cultured; Gliosis; Glutamic Acid; Hippocampus; Humans; Male; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Neurons; Receptors, N-Methyl-D-Aspartate; Serine; Synapses	2017
Acanthopanax senticosus reduces brain injury in mice exposed to low linear energy transfer radiation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 99 Topics: Animals; Brain; Brain Injuries; Eleutherococcus; Glutamic Acid; Linear Energy Transfer; Male; Medicine, Chinese Traditional; Metabolomics; Mice; Plant Extracts; Principal Component Analysis; Radiation Injuries, Experimental; Venlafaxine Hydrochloride	2018
Cognitive impairments accompanying rodent mild traumatic brain injury involve p53-dependent neuronal cell death and are ameliorated by the tetrahydrobenzothiazole PFT-α. PloS one, 2013, Volume: 8, Issue:11 Topics: Animals; Benzothiazoles; Brain Injuries; Cell Death; Cell Line; Cell Survival; Cognitive Dysfunction; Dentate Gyrus; Glutamic Acid; Humans; Male; Maze Learning; Mice; Neurons; Oxidative Stress; Primary Cell Culture; Rats; Toluene; Tumor Suppressor Protein p53	2013
Dietary therapy mitigates persistent wake deficits caused by mild traumatic brain injury. Science translational medicine, 2013, Dec-11, Volume: 5, Issue:215 Topics: Amino Acids, Branched-Chain; Animals; Behavior, Animal; Brain Injuries; Cognition; Cognitive Behavioral Therapy; Disease Models, Animal; Electroencephalography; Glutamic Acid; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Neurons; Neuropeptides; Orexins; Wakefulness	2013
LPS and TNF alpha modulate AMPA/NMDA receptor subunit expression and induce PGE2 and glutamate release in preterm fetal ovine mixed glial cultures. Journal of neuroinflammation, 2013, Dec-17, Volume: 10 Topics: Animals; Blotting, Western; Brain Injuries; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Encephalitis; Fetus; Glutamic Acid; Immunohistochemistry; Lipopolysaccharides; Neuroglia; Radioimmunoassay; Real-Time Polymerase Chain Reaction; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sheep; Tumor Necrosis Factor-alpha	2013
Myoinositol and glutamate complex neurometabolite abnormality after mild traumatic brain injury. Neurology, 2014, Feb-11, Volume: 82, Issue:6 Topics: Adult; Aspartic Acid; Brain Injuries; Case-Control Studies; Caudate Nucleus; Choline; Corpus Striatum; Creatine; Female; Globus Pallidus; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Fibers, Unmyelinated; Putamen; Thalamus; Young Adult	2014
Improved cognitive outcome after progesterone administration is associated with protecting hippocampal neurons from secondary damage studied in vitro and in vivo. Behavioural brain research, 2014, May-01, Volume: 264 Topics: Animals; Brain Injuries; Cognition Disorders; Disease Models, Animal; Glutamic Acid; Hippocampus; L-Lactate Dehydrogenase; Male; Maze Learning; Neurons; Neuroprotective Agents; Nitric Oxide Synthase Type II; Organ Culture Techniques; Progesterone; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Time Factors	2014
Blast neurotrauma impairs working memory and disrupts prefrontal myo-inositol levels in rats. Molecular and cellular neurosciences, 2014, Volume: 59 Topics: Animals; Betaine; Blast Injuries; Brain Injuries; Creatine; Ethanolamines; gamma-Aminobutyric Acid; Glutamic Acid; Glycerylphosphorylcholine; Inositol; Lactic Acid; Male; Memory, Short-Term; Pattern Recognition, Physiological; Prefrontal Cortex; Rats; Rats, Sprague-Dawley	2014
Traumatic Brain Injury Increases Cortical Glutamate Network Activity by Compromising GABAergic Control. Cerebral cortex (New York, N.Y. : 1991), 2015, Volume: 25, Issue:8 Topics: Animals; Astrocytes; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Postsynaptic Potentials; GABAergic Neurons; Glutamic Acid; Inhibitory Postsynaptic Potentials; Male; Mice, Inbred C57BL; Neural Pathways; Parvalbumins; Somatostatin; Tissue Culture Techniques	2015
Ceftriaxone alleviates early brain injury after subarachnoid hemorrhage by increasing excitatory amino acid transporter 2 expression via the PI3K/Akt/NF-κB signaling pathway. Neuroscience, 2014, May-30, Volume: 268 Topics: Animals; Apoptosis; Astrocytes; Brain Injuries; Caspase 3; Ceftriaxone; Cells, Cultured; Cognition Disorders; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Male; Neoplasm Proteins; Neurons; Neuroprotective Agents; NF-kappa B; Nucleocytoplasmic Transport Proteins; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction; Subarachnoid Hemorrhage	2014
Resveratrol protects astrocytes against traumatic brain injury through inhibiting apoptotic and autophagic cell death. Cell death & disease, 2014, Mar-27, Volume: 5 Topics: Animals; Apoptosis; Astrocytes; Autophagy; Brain Injuries; Cell Line; Cell Survival; Cytoprotection; Enzyme Activation; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Male; Mitochondria; Neuroprotective Agents; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes; Time Factors	2014
The sigma-1 receptor agonist 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) protects against newborn excitotoxic brain injury by stabilizing the mitochondrial membrane potential in vitro and inhibiting microglial activation in vivo. Experimental neurology, 2014, Volume: 261 Topics: Animals; Animals, Newborn; Apoptosis; Apoptosis Inducing Factor; Brain Injuries; Caspase 3; Disease Models, Animal; Excitatory Amino Acid Agonists; Glutamic Acid; Glycoproteins; Haloperidol; Hippocampus; Ibotenic Acid; Membrane Potential, Mitochondrial; Mice; Microglia; Neurons; Receptors, sigma; Sigma-1 Receptor; Statistics, Nonparametric	2014
The major cholesterol metabolite cholestane-3β,5α,6β-triol functions as an endogenous neuroprotectant. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Aug-20, Volume: 34, Issue:34 Topics: Adult; Animals; Brain Injuries; Cells, Cultured; Central Nervous System; Cholestanols; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Infarction, Middle Cerebral Artery; Male; Neurons; Neuroprotective Agents; Protein Binding; Rabbits; Rats; Rats, Sprague-Dawley; Spinal Cord Ischemia; Time Factors; Tissue Distribution; Young Adult	2014
Cerebral Glucose Metabolism and Sedation in Brain-injured Patients: A Microdialysis Study. Journal of neurosurgical anesthesiology, 2015, Volume: 27, Issue:3 Topics: Adult; Aged; Brain; Brain Injuries; Dose-Response Relationship, Drug; Female; Glucose; Glutamic Acid; Humans; Hypnotics and Sedatives; Lactic Acid; Male; Microdialysis; Midazolam; Middle Aged; Retrospective Studies	2015
Normobaric hyperoxia is associated with increased cerebral excitotoxicity after severe traumatic brain injury. Neurocritical care, 2015, Volume: 22, Issue:2 Topics: Adult; Brain; Brain Chemistry; Brain Injuries; Female; Glutamic Acid; Humans; Hyperoxia; Male; Microdialysis; Middle Aged; Oxygen Inhalation Therapy	2015
Evaluation of impact-induced traumatic brain injury in the Göttingen Minipig using two input modes. Traffic injury prevention, 2014, Volume: 15 Suppl 1 Topics: Animals; Aspartic Acid; Brain Injuries; Dipeptides; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Swine; Swine, Miniature	2014
Spreading depolarizations mediate excitotoxicity in the development of acute cortical lesions. Experimental neurology, 2015, Volume: 267 Topics: Analysis of Variance; Animals; Aspartic Acid; Blood Gas Analysis; Blood Pressure; Brain Injuries; Cerebral Cortex; Cortical Spreading Depression; Disease Models, Animal; Electrophysiology; Excitatory Amino Acid Agents; Female; Glutamic Acid; Humans; Infarction, Middle Cerebral Artery; Male; Microelectrodes; Rats; Rats, Sprague-Dawley	2015
[Clinical syndromes of neurotransmitter system dysfunction in severe brain injury]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2015, Volume: 115, Issue:7 Topics: Acetylcholine; Adolescent; Adult; Brain Injuries; Dopamine; Female; Glasgow Coma Scale; Glasgow Outcome Scale; Glutamic Acid; Humans; Male; Synaptic Transmission; Syndrome; Young Adult	2015
Design, synthesis and biological evaluation of tricyclic diterpene derivatives as novel neuroprotective agents against ischemic brain injury. European journal of medicinal chemistry, 2015, Oct-20, Volume: 103 Topics: Animals; Brain Injuries; Cell Survival; Diterpenes; Dose-Response Relationship, Drug; Drug Design; Glutamic Acid; Molecular Structure; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship	2015
Learning impairment by minimal cortical injury in a mouse model of Alzheimer's disease. Brain research, 2016, Apr-15, Volume: 1637 Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain Injuries; Disease Models, Animal; Glutamic Acid; Hippocampus; Large-Conductance Calcium-Activated Potassium Channels; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Neurotoxins; Parietal Lobe; Peptide Fragments; Plaque, Amyloid	2016
Comprehensive Profiling of Modulation of Nitric Oxide Levels and Mitochondrial Activity in the Injured Brain: An Experimental Study Based on the Fluid Percussion Injury Model in Rats. Journal of neurotrauma, 2017, 01-15, Volume: 34, Issue:2 Topics: Animals; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Gene Expression Profiling; Glutamic Acid; Male; Mitochondria; Nitric Oxide; Percussion; Random Allocation; Rats; Rats, Sprague-Dawley	2017
Effects of repetitive low-pressure explosive blast on primary neurons and mixed cultures. Journal of neuroscience research, 2016, Volume: 94, Issue:9 Topics: Animals; Blast Injuries; Brain Injuries; Calcium; Cell Membrane; Cell Membrane Permeability; Explosions; Glutamic Acid; Neurons; Primary Cell Culture; Rats; Reactive Oxygen Species; Recurrence	2016
Methamphetamine Induces Anhedonic-Like Behavior and Impairs Frontal Cortical Energetics in Mice. CNS neuroscience & therapeutics, 2017, Volume: 23, Issue:2 Topics: Anhedonia; Animals; Aspartic Acid; Brain Injuries; Central Nervous System Stimulants; Cerebral Cortex; Disease Models, Animal; Exploratory Behavior; Food Preferences; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 3; Glutamic Acid; Grooming; Male; Maze Learning; Methamphetamine; Mice; Mice, Inbred C57BL; Motor Activity	2017
Preserving brain function in a comatose patient with septic hyperpyrexia (41.6 °C): a case report. Journal of medical case reports, 2017, Feb-13, Volume: 11, Issue:1 Topics: Adult; Amantadine; Anticonvulsants; Brain; Brain Injuries; Cognition Disorders; Coma; Dopamine Agents; Drug Therapy, Combination; Glutamic Acid; Humans; Levetiracetam; Male; Malignant Hyperthermia; Piracetam; Tomography, X-Ray Computed	2017
Volume activated anion channel and astrocytic cellular edema in traumatic brain injury and stroke. Advances in experimental medicine and biology, 2004, Volume: 559 Topics: Animals; Astrocytes; Brain; Brain Injuries; Cats; Cell Size; Edema; Fluorenes; Glutamic Acid; Ion Channel Gating; Ion Channels; Microdialysis; Neuroprotective Agents; Rats; Stroke; Survival Analysis; Tamoxifen	2004
Acute subdural hematoma in pigs: role of volume on multiparametric neuromonitoring and histology. Journal of neurotrauma, 2008, Volume: 25, Issue:9 Topics: Animals; Brain; Brain Edema; Brain Injuries; Disease Models, Animal; Evoked Potentials, Somatosensory; Glutamic Acid; Hematoma, Subdural, Acute; Intracranial Pressure; Lactic Acid; Oxygen; Oxygen Consumption; Swine	2008
Neuroprotective effects of erythropoietin on acute metabolic and pathological changes in experimentally induced neurotrauma. Journal of neurosurgery, 2008, Volume: 109, Issue:4 Topics: Acute Disease; Animals; Brain Injuries; Disease Models, Animal; Energy Metabolism; Erythropoietin; Glucose; Glutamic Acid; Lactic Acid; Microdialysis; Neuroprotective Agents; Pyruvic Acid; Rats; Rats, Sprague-Dawley	2008
Genetic inactivation of adenosine A2A receptors attenuates acute traumatic brain injury in the mouse cortical impact model. Experimental neurology, 2009, Volume: 215, Issue:1 Topics: Analysis of Variance; Animals; Brain Edema; Brain Injuries; Cell Death; Cerebral Cortex; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Functional Laterality; Gene Expression Regulation; Glutamic Acid; In Situ Nick-End Labeling; Mice; Mice, Inbred C57BL; Mice, Knockout; Nervous System Diseases; Receptor, Adenosine A2A; Statistics, Nonparametric	2009
IFN-gamma and IL-4 differentially shape metabolic responses and neuroprotective phenotype of astrocytes. Journal of neurochemistry, 2009, Volume: 108, Issue:5 Topics: Animals; Astrocytes; Brain; Brain Injuries; Cell Hypoxia; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Glutamic Acid; Glutathione; In Situ Nick-End Labeling; Interferon-gamma; Interleukin-4; Lactic Acid; Mice; Neurons; Neuroprotective Agents; Reactive Oxygen Species; tert-Butylhydroperoxide; Th1 Cells; Th2 Cells	2009
Astaxanthin reduces ischemic brain injury in adult rats. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2009, Volume: 23, Issue:6 Topics: Aconitate Hydratase; Animals; Behavior, Animal; Brain Injuries; Brain Ischemia; Cerebrovascular Circulation; Crustacea; Cytochromes c; Diet; Glutamic Acid; Humans; In Situ Nick-End Labeling; Lipid Peroxidation; Male; Molecular Structure; Motor Activity; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Xanthophylls	2009
Neurometabolite concentrations in gray and white matter in mild traumatic brain injury: an 1H-magnetic resonance spectroscopy study. Journal of neurotrauma, 2009, Volume: 26, Issue:10 Topics: Adult; Affective Symptoms; Axons; Biomarkers; Body Water; Brain; Brain Injuries; Cognition Disorders; Corpus Callosum; Creatine; Diffuse Axonal Injury; Energy Metabolism; Female; Glutamic Acid; Glutamine; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Fibers, Myelinated; Phosphocreatine; Young Adult	2009
Dual microdialysis probe monitoring for patients with traumatic brain injury. Acta neurochirurgica. Supplement, 2008, Volume: 102 Topics: Brain Injuries; Electrochemistry; Extracellular Space; Female; Glutamic Acid; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Tomography, X-Ray Computed	2008
Delayed cerebral oxidative glucose metabolism after traumatic brain injury in young rats. Journal of neurochemistry, 2009, Volume: 109 Suppl 1 Topics: Amino Acids; Animals; Aspartic Acid; Brain Edema; Brain Injuries; Glucose; Glutamic Acid; Glutamine; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Nerve Tissue Proteins; Neurotransmitter Agents; Oxidation-Reduction; Rats; Rats, Sprague-Dawley	2009
Deficits in ERK and CREB activation in the hippocampus after traumatic brain injury. Neuroscience letters, 2009, Aug-07, Volume: 459, Issue:2 Topics: Analysis of Variance; Animals; Blotting, Western; Brain Injuries; Cyclic AMP Response Element-Binding Protein; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Phosphorylation; Potassium Chloride; Rats; Rats, Sprague-Dawley	2009
Changes in calcium-binding protein expression in human cortical contusion tissue. Journal of neurotrauma, 2009, Volume: 26, Issue:12 Topics: Adolescent; Adult; Aged; Antigens, Nuclear; Biomarkers; Brain Injuries; Calbindin 2; Calbindins; Calcium-Binding Proteins; Cerebral Cortex; Disease Progression; Female; Glial Fibrillary Acidic Protein; Gliosis; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Immunohistochemistry; Male; Middle Aged; Nerve Fibers, Myelinated; Nerve Tissue Proteins; Neurons; Parvalbumins; S100 Calcium Binding Protein G; Young Adult	2009
The human brain utilizes lactate via the tricarboxylic acid cycle: a 13C-labelled microdialysis and high-resolution nuclear magnetic resonance study. Brain : a journal of neurology, 2009, Volume: 132, Issue:Pt 10 Topics: Acetates; Adolescent; Adult; Brain; Brain Chemistry; Brain Injuries; Citric Acid Cycle; Energy Metabolism; Female; Glucose; Glutamic Acid; Glutamine; Humans; Kinetics; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Microdialysis; Middle Aged; Young Adult	2009
Neuroprotective effects of selective N-type VGCC blockade on stretch-injury-induced calcium dynamics in cortical neurons. Journal of neurotrauma, 2010, Volume: 27, Issue:1 Topics: Animals; Animals, Newborn; Astrocytes; Brain Injuries; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Calcium Signaling; Cell Survival; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Glutamic Acid; Neurons; omega-Conotoxins; Rats; Time Factors	2010
Dietary branched chain amino acids ameliorate injury-induced cognitive impairment. Proceedings of the National Academy of Sciences of the United States of America, 2010, Jan-05, Volume: 107, Issue:1 Topics: Amino Acids, Branched-Chain; Animals; Brain Injuries; Cognition Disorders; Diet; Glutamic Acid; Hippocampus; Humans; Male; Mice; Mice, Inbred C57BL; Synaptic Transmission	2010
Regionally localized recurrent excitation in the dentate gyrus of a cortical contusion model of posttraumatic epilepsy. Journal of neurophysiology, 2010, Volume: 103, Issue:3 Topics: Animals; Brain Injuries; Contusions; Data Interpretation, Statistical; Dentate Gyrus; Electrophysiology; Epilepsy; Excitatory Postsynaptic Potentials; Glutamic Acid; Immunohistochemistry; In Vitro Techniques; Male; Membrane Potentials; Mice; Mossy Fibers, Hippocampal; Patch-Clamp Techniques; Photic Stimulation; Synapses	2010
Role of extracellular glutamate measured by cerebral microdialysis in severe traumatic brain injury. Journal of neurosurgery, 2010, Volume: 113, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Injuries; Cerebrum; Extracellular Space; Female; Follow-Up Studies; Glutamic Acid; Humans; Intracranial Pressure; Male; Microdialysis; Middle Aged; Oxygen; Prognosis; Prospective Studies; Recovery of Function; Severity of Illness Index; Time Factors; Young Adult	2010
Brain metabolism is significantly impaired at blood glucose below 6 mM and brain glucose below 1 mM in patients with severe traumatic brain injury. Critical care (London, England), 2010, Volume: 14, Issue:1 Topics: Adolescent; Adult; Blood Glucose; Brain; Brain Injuries; Female; Glutamic Acid; Humans; Insulin; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Pyruvic Acid; Young Adult	2010
Diffuse brain injury elevates tonic glutamate levels and potassium-evoked glutamate release in discrete brain regions at two days post-injury: an enzyme-based microelectrode array study. Journal of neurotrauma, 2010, Volume: 27, Issue:5 Topics: Animals; Brain Injuries; Diffuse Axonal Injury; Disease Models, Animal; Enzyme Assays; Glutamic Acid; Male; Microdialysis; Microelectrodes; Potassium; Potassium Chloride; Rats; Rats, Sprague-Dawley; Up-Regulation	2010
Pre-synaptic glutamate-induced activation of DA release in the striatum after partial nigral lesion. Journal of neurochemistry, 2010, Volume: 113, Issue:6 Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids; Animals; Brain Injuries; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Agents; Electrochemotherapy; Glutamic Acid; Homovanillic Acid; Male; Microdialysis; Oxidopamine; Presynaptic Terminals; Rats; Rats, Wistar; Substantia Nigra	2010
Adenosine A2A receptors in both bone marrow cells and non-bone marrow cells contribute to traumatic brain injury. Journal of neurochemistry, 2010, Volume: 113, Issue:6 Topics: Analysis of Variance; Animals; Apoptosis; Bone Marrow Cells; Bone Marrow Transplantation; Brain Edema; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Glutamic Acid; In Situ Nick-End Labeling; Interleukin-1; Mice; Mice, Knockout; Nervous System Diseases; Neurologic Examination; Receptor, Adenosine A2A; RNA, Messenger; Tumor Necrosis Factor-alpha	2010
Chemical blocking of zinc ions in CNS increases neuronal damage following traumatic brain injury (TBI) in mice. PloS one, 2010, Apr-09, Volume: 5, Issue:4 Topics: Animals; Brain Injuries; Cell Death; Central Nervous System; Chelating Agents; Ditiocarb; Glutamic Acid; Mice; Mice, Knockout; Neurons; Sodium Selenite; Zinc	2010
Local glutamate level dictates adenosine A2A receptor regulation of neuroinflammation and traumatic brain injury. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Apr-21, Volume: 30, Issue:16 Topics: Animals; Brain Injuries; Cells, Cultured; Glutamic Acid; Inflammation; Inflammation Mediators; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Receptor, Adenosine A2A	2010
Traumatic brain injury and metabolism. Journal of neurosurgery, 2010, Volume: 112, Issue:6 Topics: Blood Flow Velocity; Blood Glucose; Brain; Brain Injuries; Craniotomy; Decompression, Surgical; Energy Metabolism; Glutamic Acid; Humans; Intracranial Pressure; Lactic Acid; Mitochondrial Diseases; Oxygen Consumption; Prognosis; Pyruvic Acid; Treatment Outcome	2010
Astrocyte oxidative metabolism and metabolite trafficking after fluid percussion brain injury in adult rats. Journal of neurotrauma, 2010, Volume: 27, Issue:12 Topics: Acetic Acid; Analysis of Variance; Animals; Astrocytes; Brain; Brain Injuries; Glucose; Glutamic Acid; Glutamine; Magnetic Resonance Spectroscopy; Male; Neurons; Random Allocation; Rats; Rats, Sprague-Dawley	2010
[Effect of (S)-4C3HPG on brain damage in the acute stage of moderate traumatic brain injury model of mice and underlying mechanism]. Sheng li xue bao : [Acta physiologica Sinica], 2010, Dec-25, Volume: 62, Issue:6 Topics: Animals; Brain Injuries; Cytokines; Glutamic Acid; Glycine; Male; Mice; Mice, Inbred C57BL; Receptors, Metabotropic Glutamate	2010
Cerebral extracellular chemistry and outcome following traumatic brain injury: a microdialysis study of 223 patients. Brain : a journal of neurology, 2011, Volume: 134, Issue:Pt 2 Topics: Adult; Biomarkers; Brain Injuries; Cerebral Cortex; Extracellular Fluid; Female; Glasgow Coma Scale; Glasgow Outcome Scale; Glucose; Glutamic Acid; Glycerol; Humans; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Pyruvic Acid	2011
Potential non-hypoxic/ischemic causes of increased cerebral interstitial fluid lactate/pyruvate ratio: a review of available literature. Neurocritical care, 2011, Volume: 15, Issue:3 Topics: Aerobiosis; Anaerobiosis; Blood Glucose; Brain; Brain Injuries; Critical Care; Energy Metabolism; Extracellular Fluid; Glutamic Acid; Glycerol; Humans; Hypoxia-Ischemia, Brain; Lactic Acid; Microdialysis; Monitoring, Physiologic; Oxidation-Reduction; Oxygen; Pyruvic Acid; Regional Blood Flow	2011
Progesterone inhibition of voltage-gated calcium channels is a potential neuroprotective mechanism against excitotoxicity. Steroids, 2011, Volume: 76, Issue:9 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Brain; Brain Injuries; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Gene Expression; Genes, Reporter; Glutamic Acid; Luciferases; Male; Membrane Potentials; N-Methylaspartate; Neurons; Neuroprotective Agents; NFATC Transcription Factors; Nifedipine; Potassium; Progesterone; Rats; Rats, Sprague-Dawley	2011
Time course of recovery from cerebral vulnerability after severe traumatic brain injury: a microdialysis study. The Journal of trauma, 2011, Volume: 71, Issue:5 Topics: Analysis of Variance; Biomarkers; Body Temperature; Brain Injuries; Extracellular Fluid; Female; Glasgow Coma Scale; Glucose; Glutamic Acid; Glycerol; Humans; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Pyruvic Acid; Time Factors	2011
Measurement of synchronous activity by microelectrode arrays uncovers differential effects of sublethal and lethal glutamate concentrations on cortical neurons. Annals of biomedical engineering, 2011, Volume: 39, Issue:8 Topics: Action Potentials; Animals; Brain Injuries; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Glutamic Acid; Microelectrodes; Neurons; Rats	2011
Effects of lisuride hydrogen maleate on pericontusional tissue metabolism, brain edema formation, and contusion volume development after experimental traumatic brain injury in rats. Neuroscience letters, 2011, Jul-25, Volume: 499, Issue:3 Topics: Animals; Brain Edema; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose; Glutamic Acid; Lactic Acid; Lisuride; Male; Microdialysis; Neuroprotective Agents; Pyruvic Acid; Rats; Rats, Sprague-Dawley	2011
Increased cerebral (R)-[(11)C]PK11195 uptake and glutamate release in a rat model of traumatic brain injury: a longitudinal pilot study. Journal of neuroinflammation, 2011, Jun-14, Volume: 8 Topics: Animals; Antineoplastic Agents; Brain; Brain Injuries; Carbon Radioisotopes; Fluorescent Dyes; Glutamic Acid; Isoquinolines; Male; Microdialysis; Pilot Projects; Positron-Emission Tomography; Rats; Rats, Wistar	2011
Closed traumatic brain injury model in sheep mimicking high-velocity, closed head trauma in humans. Central European neurosurgery, 2011, Volume: 72, Issue:3 Topics: Animals; Aspartic Acid; Brain; Brain Injuries; Carbon Dioxide; Disease Models, Animal; Electron Spin Resonance Spectroscopy; gamma-Aminobutyric Acid; Glutamic Acid; Head Injuries, Closed; Humans; Image Processing, Computer-Assisted; Intracranial Pressure; Magnetic Resonance Imaging; Oxygen Consumption; Sheep; Sheep, Domestic	2011
Neuroprotection of the leaf and stem of Vitis amurensis and their active compounds against ischemic brain damage in rats and excitotoxicity in cultured neurons. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2012, Jan-15, Volume: 19, Issue:2 Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Brain Edema; Brain Injuries; Brain Ischemia; Cyclooxygenase 2; Female; Glutamic Acid; Glutathione; Lipid Peroxidation; Male; Methanol; Molecular Structure; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Phytotherapy; Plant Extracts; Plant Leaves; Plant Stems; Pregnancy; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Vitis	2012
Enzyme-based NAND gate for rapid electrochemical screening of traumatic brain injury in serum. Analytica chimica acta, 2011, Oct-03, Volume: 703, Issue:1 Topics: Biocatalysis; Biomarkers; Brain Injuries; Buffers; Electrochemistry; Electrodes; Glutamic Acid; Humans; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Methylene Blue; NAD; Time Factors	2011
Changes in calculated arterio-jugular venous glutamate difference and SjvO2 in patients with severe traumatic brain injury. Minerva anestesiologica, 2011, Volume: 77, Issue:9 Topics: Adolescent; Adult; Anesthesia; Arteries; Body Temperature; Brain Injuries; Carbon Dioxide; Chromatography, High Pressure Liquid; Critical Care; Female; Glutamic Acid; Humans; Hypnotics and Sedatives; Intracranial Pressure; Jugular Veins; Length of Stay; Male; Middle Aged; Oxygen; Young Adult	2011
Hypersensitive glutamate signaling correlates with the development of late-onset behavioral morbidity in diffuse brain-injured circuitry. Journal of neurotrauma, 2012, Jan-20, Volume: 29, Issue:2 Topics: Afferent Pathways; Animals; Behavior, Animal; Brain Injuries; Diffuse Axonal Injury; Disease Models, Animal; Glutamic Acid; Hyperesthesia; Male; Rats; Rats, Sprague-Dawley; Signal Transduction; Time Factors	2012
Effects of a small acute subdural hematoma following traumatic brain injury on neuromonitoring, brain swelling and histology in pigs. European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2011, Volume: 47, Issue:3 Topics: Animals; Brain Edema; Brain Injuries; Cerebrovascular Circulation; Disease Models, Animal; Evoked Potentials, Somatosensory; Glutamic Acid; Hematoma, Subdural, Acute; Intracranial Pressure; Lactic Acid; Male; Monitoring, Physiologic; Sus scrofa	2011
β2 adrenergic-mediated reduction of blood glutamate levels and improved neurological outcome after traumatic brain injury in rats. Journal of neurosurgical anesthesiology, 2012, Volume: 24, Issue:1 Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Animals; Behavior, Animal; Blood Glucose; Blood Pressure; Brain Injuries; Butoxamine; Glutamic Acid; Head Injuries, Closed; Heart Rate; Hemodynamics; Isoproterenol; Male; Metoprolol; Movement; Nervous System Diseases; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-2; Treatment Outcome	2012
[Effects of β-lactam antibiotics ceftriaxone on expression of glutamate in hippocampus after traumatic brain injury in rats]. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2011, Volume: 40, Issue:5 Topics: Animals; Brain Injuries; Ceftriaxone; Disease Models, Animal; Female; Glutamic Acid; Hippocampus; Male; Rats; Rats, Sprague-Dawley	2011
The cerebral extracellular release of glycerol, glutamate, and FGF2 is increased in older patients following severe traumatic brain injury. Journal of neurotrauma, 2012, Jan-01, Volume: 29, Issue:1 Topics: Adult; Aged; Brain Injuries; Enzyme-Linked Immunosorbent Assay; Female; Fibroblast Growth Factor 2; Glasgow Coma Scale; Glasgow Outcome Scale; Glutamic Acid; Glycerol; Humans; Male; Microdialysis; Middle Aged; Retrospective Studies	2012
Cerebral metabolism after early decompression craniotomy following controlled cortical impact injury in rats. Neurological research, 2011, Volume: 33, Issue:8 Topics: Animals; Brain Injuries; Cerebral Cortex; Craniotomy; Decompression, Surgical; Disease Models, Animal; Glucose; Glutamic Acid; Humans; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Pyruvic Acid; Rats; Rats, Sprague-Dawley	2011
Post-traumatic hypoxia exacerbates neurological deficit, neuroinflammation and cerebral metabolism in rats with diffuse traumatic brain injury. Journal of neuroinflammation, 2011, Oct-28, Volume: 8 Topics: Animals; Behavior, Animal; Brain; Brain Injuries; Cytokines; Encephalitis; Glucose; Glutamic Acid; Humans; Hypoxia; Lactates; Male; Microdialysis; Neuropsychological Tests; Rats; Rats, Sprague-Dawley	2011
Effect of glutamate and blood glutamate scavengers oxaloacetate and pyruvate on neurological outcome and pathohistology of the hippocampus after traumatic brain injury in rats. Anesthesiology, 2012, Volume: 116, Issue:1 Topics: Animals; Behavior, Animal; Blood Gas Analysis; Blood Glucose; Brain; Brain Injuries; Cell Survival; Glutamic Acid; Hemodynamics; Hemoglobins; Hippocampus; Linear Models; Male; Neurologic Examination; Neurons; Oxaloacetic Acid; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence; Treatment Outcome	2012
Protection from glutamate-induced excitotoxicity by memantine. Annals of biomedical engineering, 2012, Volume: 40, Issue:5 Topics: Animals; Brain Injuries; Electrophysiological Phenomena; Excitatory Amino Acid Antagonists; Glutamic Acid; Memantine; Neurons; Neuroprotective Agents; Rats; Receptors, N-Methyl-D-Aspartate	2012
Disruptions in the regulation of extracellular glutamate by neurons and glia in the rat striatum two days after diffuse brain injury. Journal of neurotrauma, 2012, Apr-10, Volume: 29, Issue:6 Topics: Animals; Brain Injuries; Corpus Striatum; Extracellular Fluid; Glutamic Acid; Male; Neuroglia; Neurons; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction	2012
Calcium/calmodulin-dependent protein kinase II (CaMKII) inhibition induces neurotoxicity via dysregulation of glutamate/calcium signaling and hyperexcitability. The Journal of biological chemistry, 2012, Mar-09, Volume: 287, Issue:11 Topics: Action Potentials; Animals; Brain Injuries; Brain Ischemia; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Caspase 3; Cell Death; Cells, Cultured; Cycloheximide; Epilepsy; Glutamic Acid; Nerve Tissue Proteins; Neurons; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	2012
tPA-S481A prevents neurotoxicity of endogenous tPA in traumatic brain injury. Journal of neurotrauma, 2012, Jun-10, Volume: 29, Issue:9 Topics: Animals; Animals, Newborn; Apoptosis; Brain Injuries; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Cerebral Arteries; Cerebrovascular Circulation; Enzyme-Linked Immunosorbent Assay; Female; Glutamic Acid; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Necrosis; Polymerase Chain Reaction; Prostaglandins; Receptors, N-Methyl-D-Aspartate; Swine; Tissue Plasminogen Activator	2012
Early cerebral metabolic crisis after TBI influences outcome despite adequate hemodynamic resuscitation. Neurocritical care, 2012, Volume: 17, Issue:1 Topics: Adult; Blood Pressure; Brain; Brain Diseases, Metabolic; Brain Injuries; Cardiopulmonary Resuscitation; Critical Illness; Female; Glucose; Glutamic Acid; Glycerol; Heart Rate; Humans; Incidence; Lactic Acid; Male; Microdialysis; Middle Aged; Oximetry; Predictive Value of Tests; Pyruvic Acid	2012
In vitro mechanical strain trauma alters neuronal calcium responses: Implications for posttraumatic epilepsy. Epilepsia, 2012, Volume: 53 Suppl 1 Topics: Animals; Astrocytes; Brain Injuries; Calcium; Calcium Signaling; Cell Count; Cell Death; Cells, Cultured; Epilepsy; Excitatory Amino Acids; Female; Glutamic Acid; Intracellular Space; Male; Neurons; Rats; Stress, Mechanical	2012
Long-range Ca2+ waves transmit brain-damage signals to microglia. Developmental cell, 2012, Jun-12, Volume: 22, Issue:6 Topics: Adenosine Triphosphate; Animals; Brain Injuries; Calcium Signaling; Cell Death; Cell Movement; Chelating Agents; Glutamic Acid; Laser Therapy; Microglia; Zebrafish	2012
Neuroprotection by lowering cholesterol: a decrease in membrane cholesterol content reduces transporter-mediated glutamate release from brain nerve terminals. Biochimica et biophysica acta, 2012, Volume: 1822, Issue:10 Topics: Amino Acid Transport System X-AG; Animals; beta-Cyclodextrins; Brain; Brain Injuries; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Membrane; Cholesterol; Glutamic Acid; Hypoxia-Ischemia, Brain; Male; Membrane Potentials; Nerve Endings; Neuroprotective Agents; Protons; Rats; Rats, Wistar; Sodium; Stroke; Synaptic Vesicles; Synaptosomes	2012
'Long' pressure reactivity index (L-PRx) as a measure of autoregulation correlates with outcome in traumatic brain injury patients. Acta neurochirurgica, 2012, Volume: 154, Issue:9 Topics: Adult; Algorithms; Arterial Pressure; Blood Glucose; Brain; Brain Injuries; Disability Evaluation; Female; Glutamic Acid; Homeostasis; Humans; Intracranial Pressure; Lactic Acid; Male; Prognosis; Pyruvic Acid; Retrospective Studies; Survival Rate	2012
Neuroprotective effects of the sigma-1 receptor ligand PRE-084 against excitotoxic perinatal brain injury in newborn mice. Experimental neurology, 2012, Volume: 237, Issue:2 Topics: Animals; Animals, Newborn; Apoptosis; Brain Injuries; Excitatory Amino Acids; Glutamic Acid; Immunohistochemistry; In Situ Nick-End Labeling; Ligands; Mice; Microscopy, Confocal; Morpholines; Neurons; Neuroprotective Agents; Real-Time Polymerase Chain Reaction; Receptors, sigma; Sigma-1 Receptor	2012
The frontal lobe and thalamus have different sensitivities to hypoxia-hypotension after traumatic brain injury: a microdialysis study in rats. Journal of neurotrauma, 2012, Dec-10, Volume: 29, Issue:18 Topics: Animals; Blood Pressure; Brain Injuries; Cerebrovascular Circulation; Energy Metabolism; Frontal Lobe; Glucose; Glutamic Acid; Glycerol; Hypotension; Hypoxia; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Oxygen Consumption; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Renal Dialysis; Thalamus	2012
The neuroprotective effect of lactate is not due to improved glutamate uptake after controlled cortical impact in rats. Journal of neurotrauma, 2012, Aug-10, Volume: 29, Issue:12 Topics: Animals; Brain Chemistry; Brain Injuries; Cerebral Cortex; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Coumaric Acids; Extracellular Space; Glutamic Acid; Lactic Acid; Male; Microdialysis; Neuroprotective Agents; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Skull Fractures; Stereotaxic Techniques	2012
Re-evaluation of phencyclidine low-affinity or "non-NMDA" binding sites. Journal of neuroscience research, 2002, May-01, Volume: 68, Issue:3 Topics: Animals; Binding Sites; Binding, Competitive; Brain; Brain Injuries; Cerebellum; Cyclohexanes; Cyclohexenes; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Neurons; Neuroprotective Agents; Phencyclidine; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Stereoisomerism; Subcellular Fractions; Synapses; Synaptic Transmission; Tritium	2002
Long-time in-vivo metabolic monitoring following experimental brain contusion using proton magnetic resonance spectroscopy. Acta neurochirurgica. Supplement, 2002, Volume: 81 Topics: Animals; Aspartic Acid; Basal Ganglia; Biomarkers; Brain; Brain Injuries; Disease Models, Animal; Functional Laterality; Glutamic Acid; Hippocampus; Lactates; Magnetic Resonance Imaging; Male; Monitoring, Physiologic; Phosphocreatine; Rats; Rats, Sprague-Dawley; Reference Values; Taurine; Time Factors	2002
Neuronal activity determined by quantitative EEG and cortical microdialysis is increased following controlled cortical impact injury in rats. Acta neurochirurgica. Supplement, 2002, Volume: 81 Topics: Animals; Blood Glucose; Brain Injuries; Carbon Dioxide; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Functional Laterality; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Male; Microdialysis; Neurons; Oxygen; Partial Pressure; Rats; Rats, Sprague-Dawley	2002
Comparison of microdialysate arginine and glutamate levels in severely head-injured patient. Acta neurochirurgica. Supplement, 2002, Volume: 81 Topics: Arginine; Biomarkers; Brain Injuries; Craniocerebral Trauma; Glutamic Acid; Humans; Microdialysis; Monitoring, Physiologic; Nitric Oxide; Predictive Value of Tests; Time Factors	2002
Relationship between NOC/oFQ, dynorphin, and COX-2 activation in impaired NMDA cerebrovasodilation after brain injury. Journal of neurotrauma, 2002, Volume: 19, Issue:8 Topics: Animals; Animals, Newborn; Brain Injuries; Cyclooxygenase 2; Dynorphins; Enzyme Activation; Female; Glutamic Acid; Indomethacin; Isoenzymes; Male; N-Methylaspartate; Naltrexone; Nitrobenzenes; Nociceptin; Opioid Peptides; Pia Mater; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Superoxides; Swine; Vasodilation	2002
Microbial origin of glutamate, hibernation and tissue trauma: an in vivo microdialysis study. Journal of neuroscience methods, 2002, Sep-30, Volume: 119, Issue:2 Topics: Animals; Betaproteobacteria; Brain Injuries; Female; Glutamic Acid; Hibernation; Male; Microdialysis; Sciuridae	2002
Does acute hyperventilation cause cerebral ischemia in severely head-injured patients? Critical care medicine, 2002, Volume: 30, Issue:12 Topics: Brain Injuries; Brain Ischemia; Glutamic Acid; Humans; Hyperventilation; Lactic Acid; Respiration, Artificial	2002
Influence of norepinephrine and dopamine on cortical perfusion, EEG activity, extracellular glutamate, and brain edema in rats after controlled cortical impact injury. Journal of neurotrauma, 2002, Volume: 19, Issue:11 Topics: Animals; Brain Edema; Brain Injuries; Cerebral Cortex; Dopamine; Electroencephalography; Extracellular Space; Glutamic Acid; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Regional Blood Flow	2002
Calcium influx constitutes the ionic basis for the maintenance of glutamate-induced extended neuronal depolarization associated with hippocampal neuronal death. Cell calcium, 2003, Volume: 33, Issue:2 Topics: Animals; Animals, Newborn; Brain Injuries; Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Death; Cell Membrane; Cells, Cultured; Chlorides; Excitatory Amino Acid Antagonists; Extracellular Space; Gadolinium; Glutamic Acid; Hippocampus; Membrane Potentials; Nerve Degeneration; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Sodium-Calcium Exchanger; Stroke; Zinc Compounds	2003
Cerebral energy metabolism during transient hyperglycemia in patients with severe brain trauma. Intensive care medicine, 2003, Volume: 29, Issue:4 Topics: Blood Glucose; Brain Injuries; Cerebrovascular Circulation; Energy Metabolism; Female; Glutamic Acid; Glycerol; Humans; Hyperglycemia; Intracranial Pressure; Lactates; Male; Microdialysis; Prospective Studies; Pyruvic Acid	2003
Extracellular glutamine to glutamate ratio may predict outcome in the injured brain: a clinical microdialysis study in children. Pharmacological research, 2003, Volume: 48, Issue:1 Topics: Adolescent; Amino Acids; Brain Injuries; Child; Extracellular Fluid; Female; Glutamic Acid; Glutamine; Humans; Intracranial Pressure; Male; Microdialysis; Pilot Projects; Prognosis	2003
Increased adenine nucleotide translocator 1 in reactive astrocytes facilitates glutamate transport. Experimental neurology, 2003, Volume: 181, Issue:2 Topics: Adenine Nucleotide Translocator 1; Animals; Astrocytes; Atractyloside; Biological Transport; Brain Injuries; Cells, Cultured; Collodion; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Genes, Reporter; Gliosis; Glutamic Acid; Implants, Experimental; Male; Mice; Mitochondria; Polymerase Chain Reaction; Rats; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1	2003
The glutamate AMPA receptor antagonist, YM872, attenuates cortical tissue loss, regional cerebral edema, and neurological motor deficits after experimental brain injury in rats. Journal of neurotrauma, 2003, Volume: 20, Issue:3 Topics: Animals; Body Temperature; Brain Edema; Brain Injuries; Cerebral Cortex; Glutamic Acid; Imidazoles; Male; Models, Animal; Neuroprotective Agents; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Recovery of Function	2003
Effects of LY379268, a selective group II metabotropic glutamate receptor agonist on EEG activity, cortical perfusion, tissue damage, and cortical glutamate, glucose, and lactate levels in brain-injured rats. Journal of neurotrauma, 2003, Volume: 20, Issue:4 Topics: Amino Acids; Animals; Brain Edema; Brain Injuries; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Cerebrovascular Circulation; Disease Models, Animal; Electroencephalography; Glucose; Glutamic Acid; Lactic Acid; Male; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Time Factors	2003
L-glutamate decreases glucose utilization by rat cortical astrocytes. Neuroscience letters, 2003, Sep-11, Volume: 348, Issue:2 Topics: Animals; Animals, Newborn; Astrocytes; Brain Injuries; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Down-Regulation; Energy Metabolism; Excitatory Amino Acid Transporter 2; Glucose; Glutamic Acid; Glycolysis; Homeostasis; Hydrogen-Ion Concentration; Ions; Lactic Acid; Mitochondria; Oxidative Phosphorylation; Oxygen; Potassium Chloride; Rats; Rats, Sprague-Dawley	2003
[The influences of propofol on different kinds of brain injuries in rat brain slices]. Zhonghua yi xue za zhi, 2003, Jul-10, Volume: 83, Issue:13 Topics: Animals; Brain; Brain Injuries; Cerebral Cortex; Dose-Response Relationship, Drug; Free Radical Scavengers; Glucose; Glutamic Acid; Hippocampus; Hydrogen Peroxide; Hypoxia, Brain; In Vitro Techniques; Male; Neuroprotective Agents; Propofol; Rats; Rats, Sprague-Dawley; Time Factors	2003
Metabolic changes in the vicinity of brain contusions: a proton magnetic resonance spectroscopy and histology study. Journal of neurotrauma, 2003, Volume: 20, Issue:8 Topics: Animals; Aspartic Acid; Biomarkers; Brain Injuries; Choline; Creatine; Functional Laterality; Glutamic Acid; Immunohistochemistry; Inositol; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Protons; Rats; Rats, Sprague-Dawley; Taurine; Time Factors	2003
[Glutamic acid therapy of postconcussional complications]. Der Praktische Arzt, 1952, Jul-15, Volume: 6, Issue:62 Topics: Brain; Brain Injuries; Glutamates; Glutamic Acid	1952
[Pharmacopsychological studies in brain injuries after application of glutamic acid]. Deutsches medizinisches Journal, 1954, Feb-15, Volume: 5, Issue:3-4 Topics: Brain; Brain Injuries; Glutamates; Glutamic Acid; Research; Wounds and Injuries	1954
[ON THE EFFECT OF GLUTAMIC ACID ON METABOLISM, ESPECIALLY IN THE CENTRAL NERVOUS SYSTEM]. Zeitschrift fur die gesamte experimentelle Medizin, 1963, Jun-21, Volume: 137 Topics: Animals; Blood; Brain; Brain Damage, Chronic; Brain Injuries; Carbohydrate Metabolism; Carbon Isotopes; Central Nervous System; Cerebrospinal Fluid; Glutamates; Glutamic Acid; Guinea Pigs; Ketoglutaric Acids; Liver Glycogen; Research; Swine	1963
Metabolic changes during impending and manifest cerebral hypoxia in traumatic brain injury. British journal of neurosurgery, 2003, Volume: 17, Issue:4 Topics: Adolescent; Adult; Aged; Brain; Brain Injuries; Female; Glutamic Acid; Humans; Hypoxia, Brain; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Oxygen Consumption; Point-of-Care Systems; Prospective Studies	2003
Changes of mGluR4 and the effects of its specific agonist L-AP4 in a rodent model of diffuse brain injury. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2003, Volume: 10, Issue:6 Topics: Aminobutyrates; Animals; Behavior, Animal; Brain; Brain Injuries; Cell Count; Cognition Disorders; Diffuse Axonal Injury; Disease Models, Animal; Excitatory Amino Acid Agonists; Glutamic Acid; Male; Movement Disorders; Nerve Degeneration; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; RNA, Messenger; Synaptic Transmission; Treatment Outcome	2003
Potentiation of NMDA receptor-mediated synaptic responses by microglia. Brain research. Molecular brain research, 2003, Nov-26, Volume: 119, Issue:2 Topics: Animals; Animals, Newborn; Brain; Brain Injuries; Cells, Cultured; Culture Media, Conditioned; Electric Stimulation; Encephalitis; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; Microglia; Molecular Weight; N-Methylaspartate; Nerve Tissue Proteins; Organ Culture Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission	2003
Moderate controlled cortical contusion in pigs: effects on multi-parametric neuromonitoring and clinical relevance. Journal of neurotrauma, 2003, Volume: 20, Issue:12 Topics: Animals; Body Temperature; Brain Edema; Brain Injuries; Disease Models, Animal; Glucose; Glutamic Acid; Intracranial Pressure; Lactic Acid; Male; Monitoring, Physiologic; Oxygen Consumption; Pyruvic Acid; Swine	2003
[Studies on the effect of glutamic acid in brain injury sequels]. Medizinische Klinik, 1952, Mar-21, Volume: 47, Issue:12 Topics: Brain; Brain Injuries; Glutamates; Glutamic Acid; Humans; Mental Disorders; Psychotherapy	1952
Spatio-temporal changes in neurofilament proteins immunoreactivity following kainate-induced cerebellar lesion in rats. Cellular and molecular neurobiology, 2004, Volume: 24, Issue:3 Topics: Animals; Brain Injuries; Cerebellum; Disease Models, Animal; Glutamic Acid; Immunohistochemistry; Kainic Acid; Male; Nerve Fibers, Myelinated; Nerve Regeneration; Neurofilament Proteins; Neuronal Plasticity; Neurons; Neurotoxins; Purkinje Cells; Rats; Rats, Wistar; Reaction Time; Synaptophysin; Up-Regulation	2004
Presynaptic excitability as a potential target for the treatment of the traumatic cerebellum. Pharmacology, 2004, Volume: 71, Issue:4 Topics: Animals; Brain Injuries; Cerebellum; Electric Stimulation; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Neurotransmitter Uptake Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Synaptic Transmission	2004
Differential effects of prolonged isoflurane anesthesia on plasma, extracellular, and CSF glutamate, neuronal activity, 125I-Mk801 NMDA receptor binding, and brain edema in traumatic brain-injured rats. Acta neurochirurgica, 2004, Volume: 146, Issue:8 Topics: Anesthetics, Inhalation; Animals; Body Water; Brain; Brain Injuries; Dizocilpine Maleate; Drug Administration Schedule; Electroencephalography; Excitatory Amino Acid Antagonists; Glutamic Acid; Isoflurane; Rats; Receptors, N-Methyl-D-Aspartate	2004
Proton spectroscopy detected myoinositol in children with traumatic brain injury. Pediatric research, 2004, Volume: 56, Issue:4 Topics: Adolescent; Biomarkers; Brain; Brain Injuries; Child; Child, Preschool; Gliosis; Glutamic Acid; Glutamine; Humans; Infant; Inositol; Magnetic Resonance Spectroscopy; Spectrum Analysis	2004
In vivo neuroprotective adaptation of the glutamate/glutamine cycle to neuronal death. Hippocampus, 2004, Volume: 14, Issue:5 Topics: Animals; Apoptosis; Brain; Brain Injuries; Cell Death; Cell Survival; Denervation; Disease Models, Animal; Energy Metabolism; Fornix, Brain; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; Hippocampus; L-Lactate Dehydrogenase; Lactic Acid; Male; Necrosis; Nerve Degeneration; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley	2004
Patterns of energy substrates during ischemia measured in the brain by microdialysis. Journal of neurotrauma, 2004, Volume: 21, Issue:7 Topics: Adult; Brain Injuries; Brain Ischemia; Female; Glasgow Coma Scale; Glucose; Glutamic Acid; Humans; Hypoxia; Lactic Acid; Male; Microdialysis; Middle Aged; Oxygen; Pyruvic Acid; Sensitivity and Specificity	2004
Early loss of the glutamate transporter splice-variant GLT-1v in rat cerebral cortex following lateral fluid-percussion injury. Glia, 2005, Jan-01, Volume: 49, Issue:1 Topics: Alternative Splicing; Amino Acid Transport System X-AG; Animals; Brain Injuries; Carrier Proteins; Cerebral Cortex; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hippocampus; Immunohistochemistry; Intermediate Filament Proteins; Male; Nerve Degeneration; Neurons; Protein Isoforms; Rats; Rats, Sprague-Dawley; Symporters; Thalamus; Time Factors; Wounds, Nonpenetrating	2005
[Detection of amino acid neurotransmitters in cerebrospinal fluid of patients in persistent vegetative state]. Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2005, Volume: 25, Issue:1 Topics: Adolescent; Adult; Alanine; Aspartic Acid; Brain Injuries; Child; Female; Glutamic Acid; Glycine; Humans; Male; Middle Aged; Persistent Vegetative State	2005
Proton MR spectroscopy detected glutamate/glutamine is increased in children with traumatic brain injury. Journal of neurotrauma, 2004, Volume: 21, Issue:11 Topics: Adolescent; Age Factors; Aspartic Acid; Brain; Brain Injuries; Child; Child, Preschool; Choline; Coma; Disease Progression; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Nerve Degeneration; Occipital Lobe; Parietal Lobe; Predictive Value of Tests; Recovery of Function; Up-Regulation	2004
Proton MRS in acute traumatic brain injury: role for glutamate/glutamine and choline for outcome prediction. Journal of neurotrauma, 2004, Volume: 21, Issue:12 Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Injuries; Cerebral Cortex; Choline; Creatinine; Evoked Potentials, Somatosensory; Female; Follow-Up Studies; Glasgow Outcome Scale; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Time Factors	2004
Gender associations with cerebrospinal fluid glutamate and lactate/pyruvate levels after severe traumatic brain injury. Critical care medicine, 2005, Volume: 33, Issue:2 Topics: Adult; Brain Injuries; Female; Glasgow Coma Scale; Glutamic Acid; Humans; Hypothermia, Induced; Lactic Acid; Male; Pyruvic Acid; Randomized Controlled Trials as Topic; Sex Characteristics	2005
Altered expression patterns of metabotropic glutamate receptors in diffuse brain injury. Neuroscience letters, 2005, Jun-03, Volume: 380, Issue:3 Topics: Animals; Brain Injuries; Cerebral Cortex; Diffuse Axonal Injury; Disease Models, Animal; Gene Expression; Glutamic Acid; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; RNA, Messenger; Time Factors; Up-Regulation	2005
Concurrent monitoring of cerebral electrophysiology and metabolism after traumatic brain injury: an experimental and clinical study. Journal of neurotrauma, 2005, Volume: 22, Issue:7 Topics: Action Potentials; Adult; Animals; Brain Diseases, Metabolic; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Electrophysiology; Extracellular Fluid; Glucose; Glutamic Acid; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Neurons; Rats; Rats, Sprague-Dawley; Time Factors	2005
Upregulation of pentose phosphate pathway and preservation of tricarboxylic acid cycle flux after experimental brain injury. Journal of neurotrauma, 2005, Volume: 22, Issue:10 Topics: Animals; Brain Injuries; Citric Acid Cycle; Disease Models, Animal; Glucose; Glutamic Acid; Glutamine; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Pentose Phosphate Pathway; Rats; Up-Regulation	2005
Traumatic mechanical injury to the hippocampus in vitro causes regional caspase-3 and calpain activation that is influenced by NMDA receptor subunit composition. Neurobiology of disease, 2006, Volume: 22, Issue:1 Topics: Animals; Animals, Newborn; Apoptosis; Biomarkers; Brain Injuries; Calpain; Caspase 3; Caspases; Dentate Gyrus; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Mechanotransduction, Cellular; Necrosis; Neurons; Organ Culture Techniques; Protein Subunits; Rats; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Spectrin; Synaptic Transmission; Up-Regulation	2006
Intracerebral microdialysis in neurosurgical intensive care patients utilising catheters with different molecular cut-off (20 and 100 kD). Acta neurochirurgica, 2006, Volume: 148, Issue:3 Topics: Brain Chemistry; Brain Injuries; Catheters, Indwelling; Cerebral Cortex; Coma; Critical Care; Extracellular Fluid; Glucose; Glutamic Acid; Glycerol; Humans; Lactic Acid; Membranes, Artificial; Microdialysis; Molecular Weight; Monitoring, Physiologic; Nerve Tissue Proteins; Neurochemistry; Predictive Value of Tests; Subarachnoid Hemorrhage; Urea	2006
Early, transient increase in complexin I and complexin II in the cerebral cortex following traumatic brain injury is attenuated by N-acetylcysteine. Journal of neurotrauma, 2006, Volume: 23, Issue:1 Topics: Acetylcysteine; Adaptor Proteins, Vesicular Transport; Animals; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Free Radical Scavengers; Glutamic Acid; Hippocampus; Male; Nerve Degeneration; Nerve Tissue Proteins; Neurotoxins; Oxidative Stress; Rats; Rats, Sprague-Dawley; SNARE Proteins; Synaptic Membranes; Synaptic Transmission; Time Factors; Up-Regulation	2006
Cerebral cortical tissue damage after hemorrhagic hypotension in near-term born lambs. Pediatric research, 2006, Volume: 59, Issue:2 Topics: Animals; Animals, Newborn; Brain Injuries; Female; Glutamic Acid; Hemorrhage; Hypotension; Nitric Oxide; Pregnancy; Sheep	2006
Facilitation of glutamatergic synaptic transmission in hippocampal CA1 area of rats with traumatic brain injury. Neuroscience letters, 2006, Jun-19, Volume: 401, Issue:1-2 Topics: Action Potentials; Animals; Brain Injuries; Disease Models, Animal; Epilepsy; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Male; Neuronal Plasticity; Presynaptic Terminals; Pyramidal Cells; Rats; Rats, Wistar; Synaptic Transmission	2006
NAAG peptidase inhibitor increases dialysate NAAG and reduces glutamate, aspartate and GABA levels in the dorsal hippocampus following fluid percussion injury in the rat. Journal of neurochemistry, 2006, Volume: 97, Issue:4 Topics: Animals; Aspartic Acid; Brain Injuries; Cytoprotection; Dipeptides; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamate Carboxypeptidase II; Glutamic Acid; Hippocampus; Male; Microdialysis; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Up-Regulation	2006
Mechanisms underlying the inability to induce area CA1 LTP in the mouse after traumatic brain injury. Hippocampus, 2006, Volume: 16, Issue:6 Topics: Animals; Brain Injuries; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Dendritic Spines; Disease Models, Animal; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Long-Term Potentiation; Long-Term Synaptic Depression; Memory Disorders; Mice; Mice, Inbred C57BL; Neural Pathways; Organ Culture Techniques; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission	2006
Granulocyte colony-stimulating factor does not affect contusion size, brain edema or cerebrospinal fluid glutamate concentrations in rats following controlled cortical impact. Acta neurochirurgica. Supplement, 2006, Volume: 96 Topics: Animals; Brain Edema; Brain Injuries; Glutamic Acid; Granulocyte Colony-Stimulating Factor; Head Injuries, Closed; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Treatment Outcome	2006
N-methyl-D-aspartate receptor subunit changes after traumatic injury to the developing brain. Journal of neurotrauma, 2006, Volume: 23, Issue:6 Topics: Animals; Brain; Brain Injuries; Glutamic Acid; Hippocampus; Immunoblotting; Male; Nerve Tissue Proteins; Neuronal Plasticity; Parietal Lobe; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Synaptic Transmission; Synaptosomes	2006
Quantitation of ischemic events after severe traumatic brain injury in humans: a simple scoring system. Journal of neurosurgical anesthesiology, 2006, Volume: 18, Issue:3 Topics: Adult; Age Factors; Brain Chemistry; Brain Injuries; Brain Ischemia; Extracellular Fluid; Female; Glasgow Outcome Scale; Glucose; Glutamic Acid; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Neurologic Examination; Oxygen Consumption; Pyruvic Acid; Retrospective Studies; Treatment Outcome	2006
High extracellular potassium and its correlates after severe head injury: relationship to high intracranial pressure. Neurosurgical focus, 2000, Volume: 8, Issue:1 Topics: Adolescent; Adult; Astrocytes; Brain; Brain Edema; Brain Injuries; Cerebrovascular Circulation; Craniocerebral Trauma; Disease Progression; Extracellular Fluid; Glutamic Acid; Humans; Hyperkalemia; Intracranial Hypertension; Lactic Acid; Microdialysis; Potassium; Predictive Value of Tests; Regression Analysis; Up-Regulation; Water-Electrolyte Imbalance	2000
MR spectroscopy: predicting long-term neuropsychological outcome following pediatric TBI. Journal of magnetic resonance imaging : JMRI, 2006, Volume: 24, Issue:4 Topics: Adolescent; Aspartic Acid; Brain Injuries; Child; Child, Preschool; Creatine; Female; Glutamic Acid; Glutamine; Humans; Infant; Inositol; Linear Models; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Predictive Value of Tests; Recovery of Function; Statistics, Nonparametric	2006
Activin a release into cerebrospinal fluid in a subset of patients with severe traumatic brain injury. Journal of neurotrauma, 2006, Volume: 23, Issue:9 Topics: Activins; Adolescent; Adult; Aged; Brain Injuries; Case-Control Studies; Female; Follistatin; Glutamic Acid; Glycerol; Humans; Lactic Acid; Male; Middle Aged; Nerve Growth Factors; Phosphopyruvate Hydratase; Pyruvic Acid; Radiography; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Trauma Severity Indices	2006
Brain neuroprotection by scavenging blood glutamate. Experimental neurology, 2007, Volume: 203, Issue:1 Topics: Animals; Aspartate Aminotransferase, Cytoplasmic; Brain; Brain Injuries; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Glutamic Acid; Injections, Intravenous; Male; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Oxaloacetic Acid; Rats; Rats, Sprague-Dawley; Recovery of Function; Treatment Outcome	2007
Modulation of epileptiform activity by glutamine and system A transport in a model of post-traumatic epilepsy. Neurobiology of disease, 2007, Volume: 25, Issue:2 Topics: Action Potentials; Amino Acid Transport System A; Amino Acid Transport Systems; Animals; beta-Alanine; Brain Injuries; Cerebral Cortex; Cortical Spreading Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epilepsy, Post-Traumatic; Evoked Potentials; Glutamic Acid; Glutamine; Organ Culture Techniques; Rats	2007
Changes of amino acid concentrations in the rat vestibular nuclei after inferior cerebellar peduncle transection. Journal of neuroscience research, 2007, Feb-15, Volume: 85, Issue:3 Topics: Amino Acids; Animals; Brain Injuries; Cerebellum; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdissection; Rats; Rats, Sprague-Dawley; Reference Values; Vestibular Nuclei	2007
Stretch-induced injury in organotypic hippocampal slice cultures reproduces in vivo post-traumatic neurodegeneration: role of glutamate receptors and voltage-dependent calcium channels. Journal of neurochemistry, 2007, Volume: 101, Issue:2 Topics: Animals; Brain Injuries; Calcium Channel Blockers; Calcium Channels; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Membranes, Artificial; Microtubule-Associated Proteins; Models, Neurological; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Organ Culture Techniques; Physical Stimulation; Rats; Receptors, Glutamate; Silicones; Stress, Mechanical; Synaptic Transmission	2007
Glucose metabolism after traumatic brain injury: estimation of pyruvate carboxylase and pyruvate dehydrogenase flux by mass isotopomer analysis. Journal of neurotrauma, 2007, Volume: 24, Issue:1 Topics: Amino Acids; Animals; Brain Injuries; Citric Acid Cycle; Gas Chromatography-Mass Spectrometry; Glucose; Glutamic Acid; Isotopes; Male; Oxidation-Reduction; Pyruvate Carboxylase; Pyruvate Dehydrogenase Complex; Rats; Rats, Sprague-Dawley	2007
Synthes Award For Resident Research On Craniofacial And Brain Injury: effect of cyclosporin A, topiramate, or 100% oxygen as proposed "neuroprotective" therapies on the neurochemical analytes in patients with severe traumatic brain injury. Clinical neurosurgery, 2006, Volume: 53 Topics: Adult; Awards and Prizes; Brain Injuries; Case-Control Studies; Cohort Studies; Cyclosporine; Fructose; Glucose; Glutamic Acid; Humans; Lactic Acid; Microdialysis; Neuroprotective Agents; Oxygen Inhalation Therapy; Pyruvic Acid; Topiramate	2006
Thrombin potently enhances swelling-sensitive glutamate efflux from cultured astrocytes. Glia, 2007, Volume: 55, Issue:9 Topics: Animals; Animals, Newborn; Astrocytes; Brain Damage, Chronic; Brain Edema; Brain Injuries; Brain Ischemia; Calcium Signaling; Cell Death; Cells, Cultured; Enzyme Inhibitors; Extracellular Fluid; Glutamic Acid; Hypotonic Solutions; Oligopeptides; Osmotic Pressure; Rats; Receptors, Thrombin; Signal Transduction; Thrombin; Water-Electrolyte Balance	2007
Heterogeneous regional and temporal energetic impairment following controlled cortical impact injury in rats. Neurological research, 2007, Volume: 29, Issue:6 Topics: Animals; Brain; Brain Injuries; Disease Models, Animal; Energy Metabolism; Functional Laterality; Glucose; Glutamic Acid; Lactates; Magnetic Resonance Imaging; Male; Metabolic Networks and Pathways; Microdialysis; Mitochondria; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Time Factors	2007
Variations in the response of interleukins in neurosurgical intensive care patients monitored using intracerebral microdialysis. Journal of neurosurgery, 2007, Volume: 106, Issue:5 Topics: Brain; Brain Concussion; Brain Injuries; Brain Ischemia; Cathepsin D; Critical Care; Enzyme-Linked Immunosorbent Assay; Glutamic Acid; Glycerol; Hematoma, Subdural; Interleukin-1beta; Interleukin-6; Microdialysis; Monitoring, Physiologic; Postoperative Complications; Prognosis; Reference Values; Regression Analysis; Subarachnoid Hemorrhage; Vascular Endothelial Growth Factor A	2007
Resuscitation from experimental traumatic brain injury by agmatine therapy. Resuscitation, 2007, Volume: 75, Issue:3 Topics: Agmatine; Animals; Brain Injuries; Disease Models, Animal; Glutamic Acid; Hippocampus; Infusions, Parenteral; Male; Microdialysis; Neuroprotective Agents; Nitric Oxide; Rats; Rats, Sprague-Dawley; Resuscitation; Time Factors	2007
Decline in age-dependent, MK801-induced injury coincides with developmental switch in parvalbumin expression: cingulate and retrosplenial cortex. Developmental psychobiology, 2007, Volume: 49, Issue:6 Topics: Age Factors; Animals; Brain Injuries; Calbindin 2; Calcium; Caspase 3; Cell Count; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Gyrus Cinguli; Immunohistochemistry; Parvalbumins; Rats; Receptors, N-Methyl-D-Aspartate; S100 Calcium Binding Protein G	2007
Role of endothelins as mediators of injury-induced alterations of glial glutamate turnover. Journal of neuroscience research, 2008, Feb-15, Volume: 86, Issue:3 Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Astrocytes; Brain; Brain Injuries; Bucladesine; Cells, Cultured; Cerebral Cortex; Endothelins; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Extracellular Fluid; Glutamate-Ammonia Ligase; Glutamic Acid; In Vitro Techniques; Neuroglia; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries	2008
Chronic but not acute treatment with caffeine attenuates traumatic brain injury in the mouse cortical impact model. Neuroscience, 2008, Feb-19, Volume: 151, Issue:4 Topics: Animals; Brain Injuries; Caffeine; Central Nervous System Stimulants; Cerebral Cortex; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Glutamic Acid; In Situ Nick-End Labeling; Indoles; Leukocyte Common Antigens; Male; Mice; Mice, Inbred Strains; Receptor, Adenosine A1; Receptors, Adenosine A2; Time Factors	2008
Low endogenous G-protein-coupled receptor kinase 2 sensitizes the immature brain to hypoxia-ischemia-induced gray and white matter damage. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Mar-26, Volume: 28, Issue:13 Topics: Animals; Animals, Newborn; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Apoptosis; Brain Injuries; G-Protein-Coupled Receptor Kinase 2; Gene Expression Regulation, Developmental; Glutamic Acid; Hypoxia-Ischemia, Brain; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Myelin Basic Protein; Neuroglia; Neurons; Neutrophil Infiltration; Peroxidase; Regional Blood Flow; Subcellular Fractions; Time Factors	2008
Metabolic failure precedes intracranial pressure rises in traumatic brain injury: a microdialysis study. Acta neurochirurgica, 2008, Volume: 150, Issue:5 Topics: Biomarkers; Brain; Brain Injuries; Glutamic Acid; Glycerol; Humans; Intracranial Hypertension; Lactic Acid; Metabolic Diseases; Microdialysis; Osmolar Concentration; Predictive Value of Tests; Prospective Studies; Pyruvic Acid; Risk Factors	2008
[Different effects of adenosine A2A receptors in the models of traumatic brain injury and peripheral tissue injury]. Sheng li xue bao : [Acta physiologica Sinica], 2008, Apr-25, Volume: 60, Issue:2 Topics: Adenosine; Animals; Brain; Brain Injuries; Disease Models, Animal; Glutamic Acid; Mice; Mice, Knockout; Phenethylamines; Receptor, Adenosine A2A; Wound Healing	2008
Perinatal brain injury. Pathophysiology and therapeutic intervention. Annals of the New York Academy of Sciences, 1995, Sep-15, Volume: 765 Topics: Animals; Animals, Newborn; Brain; Brain Injuries; Electroencephalography; Fetal Diseases; Flunarizine; G(M1) Ganglioside; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Ischemic Attack, Transient; Microdialysis; Neuroprotective Agents; Sheep; Spectrophotometry, Infrared	1995
A 13-Mer peptide of a brain injury-derived protein supports neuronal survival and rescues neurons from injury caused by glutamate. The Journal of biological chemistry, 1995, Dec-08, Volume: 270, Issue:49 Topics: Amino Acid Sequence; Animals; Brain Injuries; Cell Survival; Cells, Cultured; Glutamic Acid; Molecular Sequence Data; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Rats; Rats, Wistar	1995
Traumatic brain injury-induced excitotoxicity assessed in a controlled cortical impact model. Journal of neurochemistry, 1993, Volume: 61, Issue:6 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Brain; Brain Injuries; Cerebral Cortex; Glutamates; Glutamic Acid; Glutamine; Male; Microdialysis; Microinjections; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Serine	1993
Glutamate release and free radical production following brain injury: effects of posttraumatic hypothermia. Journal of neurochemistry, 1995, Volume: 65, Issue:4 Topics: Animals; Brain Injuries; Free Radicals; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Hypothermia; Male; Microdialysis; Rats; Rats, Sprague-Dawley	1995
Clinical evaluation of extracellular amino acids in severe head trauma by intracerebral in vivo microdialysis. Journal of neurology, neurosurgery, and psychiatry, 1995, Volume: 59, Issue:3 Topics: Adult; Brain Chemistry; Brain Injuries; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Humans; Male; Microdialysis	1995
SOD-1 transgenic mice as a model for studies of neuroprotection in stroke and brain trauma. Annals of the New York Academy of Sciences, 1994, Nov-17, Volume: 738 Topics: Animals; Brain; Brain Concussion; Brain Injuries; Cerebellum; Cerebral Cortex; Cerebral Infarction; Cold Temperature; Free Radicals; Functional Laterality; Glutamic Acid; Humans; Ischemic Attack, Transient; Mice; Mice, Transgenic; Neurotoxins; Reference Values; Spinal Cord; Superoxide Dismutase	1994
Excitatory amino acids following brain injury. Journal of neurosurgery, 1994, Volume: 80, Issue:3 Topics: Brain Injuries; Glutamates; Glutamic Acid; Humans; Nervous System	1994
Therapeutic hypothermia is cytoprotective without attenuating the traumatic brain injury-induced elevations in interstitial concentrations of aspartate and glutamate. Journal of neurotrauma, 1993,Winter, Volume: 10, Issue:4 Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Injuries; Chromatography, High Pressure Liquid; Glutamates; Glutamic Acid; Histocytochemistry; Hypothermia, Induced; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence	1993
Massive astrocytic swelling in response to extracellular glutamate--a possible mechanism for post-traumatic brain swelling? Acta neurochirurgica. Supplementum, 1994, Volume: 60 Topics: Animals; Astrocytes; Blood-Brain Barrier; Brain Edema; Brain Injuries; Cerebral Cortex; Extracellular Space; Glutamic Acid; Inclusion Bodies; Intracellular Fluid; Male; Microscopy, Electron; Neurons; Rats; Rats, Sprague-Dawley	1994
An assessment of progression of brain edema with amino acid levels in cerebrospinal fluid and changes in electroencephalogram in an adult cat model of cold brain injury. Acta neurochirurgica. Supplementum, 1994, Volume: 60 Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Blood-Brain Barrier; Brain Edema; Brain Injuries; Cats; Electroencephalography; Evoked Potentials; Freezing; Glutamic Acid; Methionine; Motor Cortex; Phenylalanine; Serine; Synaptic Transmission; Tyrosine; Valine	1994
Superoxide and nitric oxide cooperation in hypoxia/reoxygenation-induced neuron injury. Free radical biology & medicine, 1993, Volume: 14, Issue:4 Topics: Animals; Brain Injuries; Cell Hypoxia; Cells, Cultured; Drug Synergism; Free Radicals; Glutamates; Glutamic Acid; Neurons; Nitric Oxide; Rats; Reperfusion Injury; Superoxides	1993
Intracellular calcium dynamics and cerebral injury: modeling various insults in vitro. Brain research, 1993, Jun-04, Volume: 613, Issue:1 Topics: Brain Injuries; Calcium; Cells, Cultured; Energy Metabolism; Glutamates; Glutamic Acid; Models, Neurological; N-Methylaspartate; Spinal Cord	1993
Excitatory amino acids in cerebrospinal fluid following traumatic brain injury in humans. Journal of neurosurgery, 1993, Volume: 79, Issue:3 Topics: Adolescent; Adult; Aged; Brain Injuries; Female; Glutamates; Glutamic Acid; Humans; Male; Middle Aged; Osmolar Concentration; Reference Values	1993
Differential cellular response after glutamate analog hippocampal damage. Journal of neuroscience research, 1996, May-15, Volume: 44, Issue:4 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Biomarkers; Brain; Brain Injuries; Cerebral Cortex; Cerebral Ventricles; Corpus Callosum; Glial Fibrillary Acidic Protein; Gliosis; Glutamic Acid; Hippocampus; Immunohistochemistry; Injections, Intraventricular; Kainic Acid; Male; Microglia; Neurons; Rats; Rats, Wistar	1996
Arterial-jugular vein free amino acid levels in patients with head injuries: important role of glutamine in cerebral nitrogen metabolism. The Journal of trauma, 1996, Volume: 41, Issue:4 Topics: Adolescent; Adult; Aged; Amino Acids; Brain; Brain Injuries; Female; Glutamic Acid; Glutamine; Humans; Jugular Veins; Male; Middle Aged; Nitrogen; Pulmonary Artery; Radial Artery	1996
Amphiphilic helix is essential for the activity of brain injury-derived neurotrophic peptide (BINP). FEBS letters, 1996, Nov-04, Volume: 396, Issue:2-3 Topics: Amino Acid Sequence; Animals; Brain Injuries; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Circular Dichroism; Glutamic Acid; Hippocampus; Nerve Tissue Proteins; Neurons; Parasympathetic Nervous System; Protein Structure, Secondary; Rats	1996
Brain injury after hypoxia-ischemia in newborn rats: relationship to extracellular levels of excitatory amino acids and cysteine. Brain research, 1997, Mar-07, Volume: 750, Issue:1-2 Topics: Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Injuries; Carotid Artery, Common; Cysteine; Excitatory Amino Acids; Extracellular Space; Factor Analysis, Statistical; Female; Glutamic Acid; Hypoxia, Brain; Ischemic Attack, Transient; Male; Microdialysis; Rats; Rats, Wistar; Reperfusion; Statistics, Nonparametric	1997
Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1. Science (New York, N.Y.), 1997, Jun-13, Volume: 276, Issue:5319 Topics: Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Biological Transport; Brain; Brain Injuries; Electroencephalography; Epilepsy; Gene Targeting; Glutamic Acid; Hippocampus; Mice; Mice, Inbred C57BL; Nerve Degeneration; Pyramidal Cells; Synapses; Synaptic Transmission	1997
Effect of carbon dioxide on cerebral metabolism during hypoxia-ischemia in the immature rat. Pediatric research, 1997, Volume: 42, Issue:1 Topics: Animals; Brain; Brain Injuries; Brain Ischemia; Carbon Dioxide; Cerebrovascular Circulation; Citric Acid Cycle; Glucose; Glutamic Acid; Glycolysis; Hydrogen-Ion Concentration; Hypercapnia; Hypocapnia; Hypoxia, Brain; Phosphates; Rats; Rats, Sprague-Dawley	1997
The penumbra zone of a traumatic cortical lesion: a microdialysis study of excitatory amino acid release. Acta neurochirurgica. Supplement, 1997, Volume: 70 Topics: Animals; Aspartic Acid; Brain Injuries; Excitatory Amino Acids; Glutamic Acid; Male; Microdialysis; Necrosis; Rats; Rats, Sprague-Dawley	1997
Glutamate induced astroglial swelling--methods and mechanisms. Acta neurochirurgica. Supplement, 1997, Volume: 70 Topics: Animals; Astrocytes; Brain Injuries; Cell Size; Cells, Cultured; Cerebrovascular Disorders; Glutamic Acid; Rats	1997
Nitric oxide in mechanisms of brain damage induced by neurotoxic effect of glutamate. Biochemistry. Biokhimiia, 1998, Volume: 63, Issue:7 Topics: Animals; Brain; Brain Injuries; Brain Ischemia; Epilepsy; Glutamic Acid; Humans; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Signal Transduction	1998
Factors affecting excitatory amino acid release following severe human head injury. Journal of neurosurgery, 1998, Volume: 89, Issue:4 Topics: Amino Acids; Brain Concussion; Brain Injuries; Brain Ischemia; Cell Death; Cell Size; Chromatography, High Pressure Liquid; Craniocerebral Trauma; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Exocytosis; Extracellular Space; Female; Glutamic Acid; Homeostasis; Humans; Intracranial Hypertension; Intracranial Pressure; Male; Microdialysis; Presynaptic Terminals; Treatment Outcome; Ventriculostomy	1998
Relationship between excitatory amino acid release and outcome after severe human head injury. Acta neurochirurgica. Supplement, 1998, Volume: 71 Topics: Animals; Aspartic Acid; Brain Damage, Chronic; Brain Injuries; Cerebral Cortex; Excitatory Amino Acids; Glasgow Coma Scale; Glutamic Acid; Humans; Microdialysis; Outcome Assessment, Health Care; Prognosis; Rats	1998
Traumatic brain injury alters synaptic homeostasis: implications for impaired mitochondrial and transport function. Journal of neurotrauma, 1998, Volume: 15, Issue:10 Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Biological Transport, Active; Brain; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Glucose; Glutamic Acid; Hippocampus; Homeostasis; Lipid Peroxidation; Male; Mitochondria; Nerve Degeneration; Oxidative Stress; Rats; Rats, Sprague-Dawley; Synapses; Synaptosomes; Time Factors	1998
Increase in extracellular glutamate caused by reduced cerebral perfusion pressure and seizures after human traumatic brain injury: a microdialysis study. Journal of neurosurgery, 1998, Volume: 89, Issue:6 Topics: Adult; Biomarkers; Blood Pressure; Brain Injuries; Brain Ischemia; Cerebrovascular Circulation; Extracellular Space; Female; Glutamic Acid; Humans; Male; Microdialysis; Middle Aged; Prospective Studies; Retrospective Studies; Wounds and Injuries	1998
Glutamate and taurine are increased in ventricular cerebrospinal fluid of severely brain-injured patients. Journal of neurotrauma, 1999, Volume: 16, Issue:2 Topics: Adult; Aged; Analysis of Variance; Biomarkers; Brain Concussion; Brain Edema; Brain Injuries; Cerebral Ventricles; Disease Progression; Female; Glasgow Coma Scale; Glutamic Acid; Humans; Longitudinal Studies; Male; Middle Aged; Monitoring, Physiologic; Severity of Illness Index; Taurine	1999
Fluid percussion brain injury exacerbates glutamate-induced focal damage in the rat. Journal of neurotrauma, 1999, Volume: 16, Issue:3 Topics: Animals; Brain Injuries; Excitatory Amino Acid Agonists; Glutamic Acid; Image Processing, Computer-Assisted; Male; Microdialysis; Neurons; Paraffin Embedding; Rats; Rats, Sprague-Dawley; Tissue Fixation	1999
Brain temperature modifies glutamate neurotoxicity in vivo. Journal of neurotrauma, 1999, Volume: 16, Issue:4 Topics: Analysis of Variance; Animals; Body Temperature; Brain; Brain Injuries; Carbon Radioisotopes; Disease Models, Animal; Disease Progression; Glutamic Acid; Hyperthermia, Induced; Hypothermia, Induced; Male; Microdialysis; Nerve Degeneration; Neurons; Rats; Rats, Wistar; Sucrose; Time Factors	1999
Distinguishing excitotoxic from apoptotic neurodegeneration in the developing rat brain. The Journal of comparative neurology, 1999, Jun-14, Volume: 408, Issue:4 Topics: Animals; Apoptosis; Brain; Brain Injuries; Electrophoresis, Agar Gel; Glial Fibrillary Acidic Protein; Glutamic Acid; In Situ Nick-End Labeling; Microglia; Microscopy, Electron; Nerve Degeneration; Rats; Rats, Sprague-Dawley; Silver Staining	1999
Use-dependent exaggeration of brain injury: is glutamate involved? Experimental neurology, 1999, Volume: 157, Issue:2 Topics: Analysis of Variance; Animals; Brain Injuries; Dizocilpine Maleate; Forelimb; Functional Laterality; Glutamic Acid; Male; Microdialysis; Motor Activity; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex; Time Factors	1999
CSF and ECF glutamate concentrations in head injured patients. Acta neurochirurgica. Supplement, 1999, Volume: 75 Topics: Adult; Aged; Brain Injuries; Chromatography, High Pressure Liquid; Extracellular Space; Glasgow Coma Scale; Glutamic Acid; Humans; Hydrocephalus, Normal Pressure; Microdialysis; Middle Aged; Potassium; Sodium Chloride	1999
Glucose and lactate metabolism after severe human head injury: influence of excitatory neurotransmitters and injury type. Acta neurochirurgica. Supplement, 1999, Volume: 75 Topics: Adult; Brain Injuries; Female; Glasgow Coma Scale; Glucose; Glutamic Acid; Humans; Lactic Acid; Male; Microdialysis; Time Factors	1999
Evidence for time-dependent glutamate-mediated glycolysis in head-injured patients: a microdialysis study. Acta neurochirurgica. Supplement, 1999, Volume: 75 Topics: Adult; Brain Injuries; Female; Glasgow Coma Scale; Glucose; Glutamic Acid; Glycolysis; Humans; Lactic Acid; Male; Microdialysis; Time Factors	1999
Determinants of cerebral extracellular potassium after severe human head injury. Acta neurochirurgica. Supplement, 1999, Volume: 75 Topics: Adolescent; Adult; Biomarkers; Brain; Brain Injuries; Extracellular Space; Female; Glasgow Coma Scale; Glutamic Acid; Humans; Lactic Acid; Male; Microdialysis; Potassium; Time Factors; Tomography, X-Ray Computed	1999
Effect of hypocapnea on CBF and extracellular intermediates of secondary brain injury. Acta neurochirurgica. Supplement, 1999, Volume: 75 Topics: Brain; Brain Injuries; Carbon Dioxide; Chromatography, High Pressure Liquid; Extracellular Space; Glasgow Coma Scale; Glutamic Acid; Hematoma, Subdural; Humans; Hyperventilation; Hypocapnia; Intracranial Pressure; Lactic Acid; Microdialysis; Pyruvic Acid; Time Factors	1999
Monitoring by subcutaneous microdialysis in neurosurgical intensive care. Acta neurochirurgica. Supplement, 1999, Volume: 75 Topics: Adolescent; Aged; Blood Glucose; Brain Injuries; Chromatography, High Pressure Liquid; Female; Glutamic Acid; Humans; Hypoxia; Intensive Care Units; Lactic Acid; Male; Microdialysis; Monitoring, Physiologic; Plasma; Time Factors	1999
Alterations in calcium-mediated signal transduction after traumatic injury of cortical neurons. Cell calcium, 1999, Volume: 26, Issue:6 Topics: Animals; Brain Injuries; Calcium; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Cycloleucine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; N-Methylaspartate; Neuroglia; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Thapsigargin	1999
Real-time monitoring of glutamate following fluid percussion brain injury with hypoxia in the rat. Journal of neurotrauma, 2000, Volume: 17, Issue:2 Topics: Animals; Biosensing Techniques; Blood Pressure; Brain; Brain Injuries; Carbon Dioxide; Caspase 3; Caspases; Coloring Agents; Glutamic Acid; Hypoxia, Brain; Male; Microdialysis; Oxygen; Partial Pressure; Rats; Rats, Sprague-Dawley; Reference Values; Tetrazolium Salts	2000
Significant reduction in brain swelling by administration of nonpeptide kinin B2 receptor antagonist LF 16-0687Ms after controlled cortical impact injury in rats. Journal of neurosurgery, 2000, Volume: 92, Issue:5 Topics: Analysis of Variance; Animals; Body Water; Bradykinin Receptor Antagonists; Brain Chemistry; Brain Edema; Brain Injuries; Glutamic Acid; Hypoxanthine; Injections, Subcutaneous; Kinins; Male; Neuroprotective Agents; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Taurine; Xanthine	2000
In vivo glutamine hydrolysis in the formation of extracellular glutamate in the injured rat brain. Journal of neuroscience research, 2000, Jun-01, Volume: 60, Issue:5 Topics: Animals; Behavior, Animal; Brain; Brain Injuries; Excitatory Amino Acid Agonists; Extracellular Space; Glutamic Acid; Glutamine; Hydrolysis; Male; Microdialysis; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Time Factors	2000
Temporal profile of cerebrospinal fluid glutamate, interleukin-6, and tumor necrosis factor-alpha in relation to brain edema and contusion following controlled cortical impact injury in rats. Neuroscience letters, 2000, Jul-07, Volume: 288, Issue:1 Topics: Animals; Brain Edema; Brain Injuries; Glutamic Acid; Interleukin-6; Male; Neurotoxins; Rats; Rats, Sprague-Dawley; Time Factors; Tumor Necrosis Factor-alpha	2000
Clinical cerebral microdialysis: a methodological study. Journal of neurosurgery, 2000, Volume: 93, Issue:1 Topics: Adult; Blood Glucose; Brain Chemistry; Brain Injuries; Catheters, Indwelling; Chromatography, High Pressure Liquid; Critical Care; Extracellular Space; Frontal Lobe; Glutamic Acid; Humans; Intracranial Pressure; Lactic Acid; Microdialysis; Monitoring, Physiologic; Online Systems; Pyruvic Acid; Subarachnoid Hemorrhage	2000
Increased cerebrospinal fluid glutamate and taurine concentrations are associated with traumatic brain edema formation in rats. Brain research, 2000, Sep-01, Volume: 875, Issue:1-2 Topics: Amino Acids; Animals; Body Water; Brain; Brain Edema; Brain Injuries; Glutamic Acid; Male; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Reference Values; Taurine	2000
NOC/oFQ contributes to age-dependent impairment of NMDA-induced cerebrovasodilation after brain injury. American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:5 Topics: Aging; Animals; Animals, Newborn; Arterioles; Blood Pressure; Brain Injuries; Cerebrovascular Circulation; Disease Models, Animal; Excitatory Amino Acids; Female; Glutamic Acid; Male; N-Methylaspartate; Narcotic Antagonists; Nociceptin; Nociceptin Receptor; Opioid Peptides; Peptide Fragments; Pia Mater; Receptors, Opioid; Swine; Vasoconstriction; Vasodilation; Wounds, Nonpenetrating	2000
mGluR5 antagonists 2-methyl-6-(phenylethynyl)-pyridine and (E)-2-methyl-6-(2-phenylethenyl)-pyridine reduce traumatic neuronal injury in vitro and in vivo by antagonizing N-methyl-D-aspartate receptors. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:1 Topics: Animals; Brain Injuries; Cell Survival; Cells, Cultured; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Hydrolysis; Male; Maze Learning; Memory; N-Methylaspartate; Neurons; Neuroprotective Agents; Phosphatidylinositols; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate	2001
Excitatory amino acid concentrations in ventricular cerebrospinal fluid after severe traumatic brain injury in infants and children: the role of child abuse. The Journal of pediatrics, 2001, Volume: 138, Issue:1 Topics: Adolescent; Age Factors; Aspartic Acid; Brain Injuries; Brain Ischemia; Case-Control Studies; Cerebral Ventricles; Child; Child Abuse; Child, Preschool; Disabled Persons; Excitatory Amino Acids; Glasgow Coma Scale; Glasgow Outcome Scale; Glutamic Acid; Glycine; Humans; Infant; Prognosis; Survival Analysis; Time Factors; Tomography, X-Ray Computed	2001
Effects of dopamine on posttraumatic cerebral blood flow, brain edema, and cerebrospinal fluid glutamate and hypoxanthine concentrations. Critical care medicine, 2000, Volume: 28, Issue:12 Topics: Animals; Blood Flow Velocity; Blood Gas Analysis; Brain Edema; Brain Injuries; Cardiotonic Agents; Cerebrospinal Fluid; Cerebrovascular Circulation; Disease Models, Animal; Dopamine; Drug Evaluation, Preclinical; Glutamic Acid; Hypoxanthine; Laser-Doppler Flowmetry; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors	2000
Traumatic injury of cultured astrocytes alters inositol (1,4,5)-trisphosphate-mediated signaling. Glia, 2001, Volume: 33, Issue:1 Topics: Animals; Animals, Newborn; Astrocytes; Brain Injuries; Cells, Cultured; Cycloleucine; Estrenes; Extracellular Space; Glutamic Acid; Inositol 1,4,5-Trisphosphate; Neomycin; Neuroprotective Agents; Phosphodiesterase Inhibitors; Protein Synthesis Inhibitors; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Signal Transduction; Stress, Mechanical; Type C Phospholipases	2001
Riluzole reduces brain swelling and contusion volume in rats following controlled cortical impact injury. Journal of neurotrauma, 2000, Volume: 17, Issue:12 Topics: Animals; Body Water; Brain; Brain Edema; Brain Injuries; Cerebral Cortex; Glutamic Acid; Hypoxanthine; Male; Neuroprotective Agents; Organ Size; Rats; Rats, Sprague-Dawley; Riluzole; Taurine	2000
A new model for diffuse brain injury by rotational acceleration: II. Effects on extracellular glutamate, intracranial pressure, and neuronal apoptosis. Journal of neurotrauma, 2001, Volume: 18, Issue:3 Topics: Acceleration; Amino Acids; Animals; Apoptosis; Brain Injuries; Cerebellum; Disease Models, Animal; Genes, jun; Glutamic Acid; Glycine; Head Movements; Hippocampus; Intracranial Hypertension; Neurons; Rabbits; Rotation	2001
Effects of tacrolimus on hemispheric water content and cerebrospinal fluid levels of glutamate, hypoxanthine, interleukin-6, and tumor necrosis factor-alpha following controlled cortical impact injury in rats. Journal of neurosurgery, 2001, Volume: 94, Issue:5 Topics: Animals; Brain Edema; Brain Injuries; Calcineurin; Cerebral Cortex; Energy Metabolism; Glutamic Acid; Hypoxanthine; Immunosuppressive Agents; Interleukin-6; Male; Rats; Rats, Sprague-Dawley; Tacrolimus; Tumor Necrosis Factor-alpha; Water	2001
17beta-Estradiol reduces cortical lesion size in the glutamate excitotoxicity model by enhancing extracellular lactate: a new neuroprotective pathway. Brain research, 2001, May-18, Volume: 901, Issue:1-2 Topics: Animals; Brain Injuries; Cerebral Cortex; Cerebral Infarction; Disease Models, Animal; Estradiol; Extracellular Space; Glutamic Acid; Hypoxia-Ischemia, Brain; Lactic Acid; Male; Microdialysis; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Rats, Wistar	2001
The synergistic effect of high K+ and hypoxia on extracellular concentrations of neuroactive amino acid in hippocampus. Acta neurochirurgica. Supplement, 2000, Volume: 76 Topics: Animals; Brain; Brain Edema; Brain Injuries; Extracellular Space; Glutamic Acid; Hippocampus; Hypoxia, Brain; Male; Potassium; Rats; Rats, Sprague-Dawley	2000
Extracellular glutamate and aspartate in head injured patients. Acta neurochirurgica. Supplement, 2000, Volume: 76 Topics: Adolescent; Adult; Aspartic Acid; Brain Edema; Brain Injuries; Extracellular Space; Female; Glasgow Outcome Scale; Glutamic Acid; Humans; Male; Microdialysis; Middle Aged; Prognosis	2000
On-line monitoring of substrate delivery and brain metabolism in head injury. Acta neurochirurgica. Supplement, 2000, Volume: 76 Topics: Adolescent; Adult; Aged; Blood Glucose; Brain Injuries; Catheters, Indwelling; Energy Metabolism; Female; Frontal Lobe; Glutamic Acid; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Online Systems; Prognosis; Pyruvic Acid; Survival Rate	2000
Substrate delivery and ionic balance disturbance after severe human head injury. Acta neurochirurgica. Supplement, 2000, Volume: 76 Topics: Acid-Base Equilibrium; Brain; Brain Edema; Brain Injuries; Carbon Dioxide; Glutamic Acid; Humans; Lactic Acid; Membrane Potentials; Oxygen Consumption; Potassium; Prognosis; Regional Blood Flow; Water-Electrolyte Balance	2000
Induced mitochondrial failure in the feline brain: implications for understanding acute post-traumatic metabolic events. Brain research, 2001, Jul-20, Volume: 908, Issue:1 Topics: Animals; Brain; Brain Injuries; Carbon Dioxide; Cats; Cerebrovascular Circulation; Energy Metabolism; Extracellular Space; Glucose; Glutamic Acid; Hydrogen-Ion Concentration; Lactic Acid; Male; Microscopy, Electron; Mitochondria; Neurons; Oxygen; Perfusion; Potassium Cyanide; Pyruvic Acid	2001
Post-insult activity is a major cause of delayed neuronal death in organotypic hippocampal slices exposed to glutamate. Neuroscience, 2001, Volume: 105, Issue:1 Topics: Action Potentials; Animals; Brain Injuries; Brain Ischemia; Cell Death; Epilepsy; Glutamic Acid; Hippocampus; Nerve Degeneration; Nerve Net; Neurotoxins; Organ Culture Techniques; Pyramidal Cells; Rats; Tetrodotoxin; Time Factors	2001
Early expression of glutamate transporter proteins in ramified microglia after controlled cortical impact injury in the rat. Glia, 2001, Volume: 35, Issue:3 Topics: Amino Acid Transport System X-AG; Animals; Astrocytes; ATP-Binding Cassette Transporters; Brain Injuries; Cerebral Cortex; Excitatory Amino Acid Transporter 2; Extracellular Space; Glial Fibrillary Acidic Protein; Glutamic Acid; Hippocampus; Immunohistochemistry; Lectins; Macrophages; Male; Microglia; Rats; Rats, Sprague-Dawley; Receptors, Neurotransmitter; Thalamus; Time Factors	2001
Neurochemical characterization of traumatic brain injury in humans. Journal of neurotrauma, 2001, Volume: 18, Issue:8 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Chemistry; Brain Injuries; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glial Fibrillary Acidic Protein; Gliosis; Glutamic Acid; Humans; Male; Middle Aged; Radioligand Assay; Synaptosomes; Tritium	2001
Brain energy metabolism during controlled reduction of cerebral perfusion pressure in severe head injuries. Intensive care medicine, 2001, Volume: 27, Issue:7 Topics: Adolescent; Adult; Aged; Biomarkers; Brain Injuries; Cerebrovascular Circulation; Child; Child, Preschool; Energy Metabolism; Female; Glucose; Glutamic Acid; Glycerol; Hemodynamics; Humans; Infant; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Prospective Studies; Pyruvic Acid	2001
Lactate reduces glutamate-induced neurotoxicity in rat cortex. Journal of neuroscience research, 2001, Dec-01, Volume: 66, Issue:5 Topics: Animals; Brain Injuries; Cerebral Cortex; Drug Interactions; Extracellular Space; Glucose; Glutamic Acid; Immunohistochemistry; Isomerism; Lactic Acid; Male; Microdialysis; Microtubule-Associated Proteins; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Rats, Inbred Strains	2001
Endothelin downregulates the glutamate transporter GLAST in cAMP-differentiated astrocytes in vitro. Glia, 2002, Volume: 37, Issue:2 Topics: Actin Cytoskeleton; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Astrocytes; Brain Injuries; Bucladesine; Cell Differentiation; Cell Size; Cells, Cultured; Down-Regulation; Endothelin Receptor Antagonists; Endothelins; Glial Fibrillary Acidic Protein; Glutamic Acid; Immunohistochemistry; Nerve Degeneration; Rats; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin	2002
[Protective effect of c-fos antisense oligonucleotides on brain damage induced by glutamate]. Zhonghua yi xue za zhi, 2001, Feb-10, Volume: 81, Issue:3 Topics: Animals; Brain Injuries; Calcium; Disease Models, Animal; Female; Glutamic Acid; Male; Oligonucleotides, Antisense; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Sodium; Synaptosomes; Water	2001
Increased adenosine in cerebrospinal fluid after severe traumatic brain injury in infants and children: association with severity of injury and excitotoxicity. Critical care medicine, 2001, Volume: 29, Issue:12 Topics: Adenosine; Adolescent; Brain Injuries; Case-Control Studies; Child; Child Abuse; Child, Preschool; Excitatory Amino Acids; Glasgow Coma Scale; Glasgow Outcome Scale; Glutamic Acid; Humans; Infant; Linear Models; Multivariate Analysis; Pennsylvania; Prospective Studies; Time Factors	2001
Putting together the pieces. Critical care medicine, 2001, Volume: 29, Issue:12 Topics: Adenosine; Brain Injuries; Child; Glasgow Coma Scale; Glutamic Acid; Humans; Infant	2001
Molecular signatures of brain injury after intracerebral hemorrhage. Neurology, 2002, Feb-26, Volume: 58, Issue:4 Topics: Aged; Biomarkers; Brain Injuries; Cerebral Hemorrhage; Cohort Studies; Cytokines; Female; Glutamic Acid; Humans; Linear Models; Male; Middle Aged; Odds Ratio; Prospective Studies; Statistics, Nonparametric	2002
Relationship between brain temperature, brain chemistry and oxygen delivery after severe human head injury: the effect of mild hypothermia. Neurological research, 2002, Volume: 24, Issue:2 Topics: Adolescent; Adult; Aged; Aspartic Acid; Body Temperature; Brain; Brain Chemistry; Brain Injuries; Carbon Dioxide; Extracellular Space; Glucose; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Hypothermia, Induced; Intracranial Hypertension; Lactic Acid; Microdialysis; Middle Aged; Oxygen Consumption; Treatment Outcome	2002
Amino acid concentrations in the blood of the jugular vein and peripheral artery after traumatic brain injury: decreased release of glutamate into the jugular vein in the early phase. Journal of neurotrauma, 2002, Volume: 19, Issue:2 Topics: Adolescent; Adult; Aged; Amino Acids; Arteries; Aspartic Acid; Brain Injuries; Cystine; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Jugular Veins; Male; Middle Aged	2002
Correlation between cerebral blood flow, substrate delivery, and metabolism in head injury: a combined microdialysis and triple oxygen positron emission tomography study. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2002, Volume: 22, Issue:6 Topics: Adolescent; Adult; Brain; Brain Chemistry; Brain Injuries; Cerebrovascular Circulation; Female; Glucose; Glutamic Acid; Humans; Hyperventilation; Lactic Acid; Male; Microdialysis; Middle Aged; Pyruvic Acid; Tomography, Emission-Computed	2002
Regulation of interstitial excitatory amino acid concentrations after cortical contusion injury. Brain research, 2002, May-10, Volume: 935, Issue:1-2 Topics: Animals; Aspartic Acid; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Excitatory Amino Acids; Extracellular Space; Glucose; Glutamic Acid; Glycine; Hippocampus; Male; Microdialysis; Neurons; Rats; Rats, Sprague-Dawley; Sodium Channels; Up-Regulation	2002
Pretreatment with NMDA antagonists limits release of excitatory amino acids following traumatic brain injury. Neuroscience letters, 1992, Mar-02, Volume: 136, Issue:2 Topics: Amino Acids; Animals; Brain Injuries; Chromatography, High Pressure Liquid; Dextrorphan; Dialysis; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Pipecolic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate	1992
Intravenous glutamate enhances edema formation after a freezing lesion. Advances in neurology, 1990, Volume: 52 Topics: Animals; Blood-Brain Barrier; Body Water; Brain; Brain Chemistry; Brain Edema; Brain Injuries; Cold Temperature; Glutamates; Glutamic Acid; Infusions, Intravenous; Male; Organ Size; Rats; Rats, Inbred Strains; Sodium	1990
Role of neuroexcitation in development of blood-brain barrier and oedematous changes following cerebral ischaemia and traumatic brain injury. Acta neurochirurgica. Supplementum, 1990, Volume: 51 Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Brain Injuries; Brain Ischemia; Calcium; Gerbillinae; Glutamates; Glutamic Acid; Serum Albumin	1990
The role of excitatory amino acids and NMDA receptors in traumatic brain injury. Science (New York, N.Y.), 1989, May-19, Volume: 244, Issue:4906 Topics: Animals; Aspartic Acid; Binding, Competitive; Brain; Brain Injuries; Dextrorphan; Glutamates; Glutamic Acid; Magnesium; Magnetic Resonance Spectroscopy; Male; N-Methylaspartate; Phosphates; Phosphocreatine; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1989
Astrocytic swelling in traumatic-hypoxic brain injury. Beneficial effects of an inhibitor of anion exchange transport and glutamate uptake in glial cells. Molecular and chemical neuropathology, 1989, Volume: 11, Issue:1 Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Astrocytes; Biological Transport; Brain; Brain Injuries; Cats; Cells, Cultured; Chlorides; Disease Models, Animal; Fluorenes; Glutamates; Glutamic Acid; Hypoxia, Brain; Ouabain; Potassium; Rats	1989