glutamic acid has been researched along with Brain Infarction in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 27 (64.29) | 29.6817 |
| 2010's | 15 (35.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bechberger, JF; Kozoriz, MG; Lai, S; Naus, CC; Sáez, JC; Sin, WC; Vega, JL | 1 |
| Klein, J; Koch, KA; Schwarzkopf, TM | 1 |
| Arunachalam, P; Bernreuther, C; Daehn, T; Friese, MA; Gelderblom, M; Gerloff, C; Glatzel, M; Ludewig, P; Magnus, T; Matschke, J; Schattling, B | 1 |
| Badawi, Y; Hui, D; Michaelis, EK; Pal, R; Shi, H | 1 |
| Chen, Y; Chua, BH; Hamdy, RC; Jin, X; Kong, J; Li, X; Miao, Z; Tan, X; Wang, Y; Xu, X; Zhao, H | 1 |
| Abbruscato, TJ; Islam, MR; Karamyan, VT; Yang, L | 1 |
| Gan, Y; Han, P; Li, S; Li, Y; Liu, Q; Shi, J; Tang, Z; Wang, C; Wang, J; Yin, J | 1 |
| Bergman, J; Chuang, DM; Kozikowski, A; Leeds, P; Leng, Y; Liao, HM; Wang, J; Wang, Z | 1 |
| Greig, NH; Li, Y; Tamargo, IA; Wang, Y; Wu, KJ; Yu, SJ | 1 |
| Chen, J; Guan, QH; Han, D; Hou, XY; Jiang, HX; Li, C; Liu, XM; Pei, DS; Wang, XT; Wen, XR; Zhang, GY | 1 |
| Baudry, M; Bi, X; Cheung, S; Galeano, J; Liao, G; Nguyen, N; Zhou, M | 1 |
| Funke-Kaiser, H; Godes, M; Hörtnagl, H; Krikov, M; Lucht, K; Müller, S; Namsolleck, P; Neumann, C; Rumschüssel, K; Schefe, JH; Schmerbach, K; Steckelings, UM; Thöne-Reineke, C; Unger, T; Villringer, A | 1 |
| Lin, N; Liu, C; Qiu, Y; Wu, B | 1 |
| Furuta, K; Hokamura, K; Ibaraki, K; Maeda, M; Suzuki, M; Thura, M; Umemura, K; Yamamoto, S | 1 |
| Amantea, D; Bagetta, G; Corasaniti, MT; Fratto, V; Maida, S; Nappi, G; Ragusa, S; Rotiroti, D | 1 |
| Böger, RH; Choe, CU; Donzelli, S; Espey, MG; Fischer, G; Gerloff, C; Hewett, SJ; Hummel, FC; King, SB; Lewerenz, J; Magnus, T; Schwedhelm, E; Uliasz, TF | 1 |
| Chen, JF; Duan, W; Gui, L; Li, C; Tian, H; Zheng, J; Zhu, J | 1 |
| Davaki, P; Hatzimanolis, A; Markakis, I; Poulopoulou, C; Rombos, A; Tsaltas, E; Vassilopoulos, D | 1 |
| Chen, H; Jiang, Y; Li, C; Li, H; Yan, Z; Yang, J; Zhang, Z | 1 |
| Hu, YS; Jia, J; Wu, Y; Zhang, F | 1 |
| Boyko, M; Gruenbaum, BF; Gruenbaum, SE; Kuts, R; Melamed, I; Ohayon, S; Regev, A; Shapira, Y; Teichberg, VI; Zlotnik, A | 1 |
| Kumari, S; Li, PA; Mehta, SL; Mendelev, N | 1 |
| Chen, Z; Fan, YY; He, P; Hu, WW; Shen, Y; Shen, Z; Wang, XF; Zhang, XN | 1 |
| Castillo, J; Dávalos, A; Leira, R; Lizasoain, I; Moro, MA; Serena, J | 1 |
| Mendelowitsch, A; Ritz, MF; Schmidt, P | 1 |
| Hara, H; Morimoto, N; Nagai, H; Shimazawa, M; Yamashima, T | 1 |
| Arteni, NS; Lavinsky, D; Moretto, MB; Netto, CA; Rocha, JB; Souza, DO; Wofchuk, S | 1 |
| Camm, EJ; Gibbs, ME; Harding, R; Mulder, T; Rees, SM | 1 |
| Baik, EJ; Jung, YS; Kim, SU; Lee, BK; Lee, S; Lee, SH; Moon, CH; Park, HS; Park, S; Yi, KY; Yoo, SE | 1 |
| Helps, SC; Nilsson, M; Sims, NR; Thoren, AE | 1 |
| Kuroiwa, T; Makita, K; Tanaka, K; Yamashita, A | 1 |
| Cho, JH; Koh, PO; Won, CK | 1 |
| Brinkman, BC; Haddad, GG; Shu, Y; Wang, J; Yao, H | 1 |
| Kaczmarek, L; Michaluk, P | 1 |
| Battú, CE; Boff, B; Godinho, G; Gottfried, C; Pires, TD; Salbego, C; Souza, DO; Thomazi, AP; Wofchuk, ST | 1 |
| Fukunaga, K; Han, F; Moriguchi, S; Qin, ZH; Shioda, N | 1 |
| Chou, YC; Liao, JF; Liou, KT; Shen, YC; Wang, WY; Wang, YH; Yen, JC | 1 |
| Feustel, PJ; Kimelberg, HK; Zhang, H; Zhang, Y | 1 |
| Blank, T; Han, JL; Kollmar, R; Schwab, S; Tobyas, B | 1 |
| Castellanos, M; Castillo, J; Dávalos, A; Leira, R; Pumar, JM; Serena, J | 1 |
| Narita, K; Sano, K; Sato, T; Shirasaki, Y; Takagi, K; Tamura, A | 1 |
| Castellanos, M; Castillo, J; Chamorro, A; Dávalos, A; García, MM; Leira, R; Serena, J | 1 |
1 review(s) available for glutamic acid and Brain Infarction
| Article | Year |
|---|---|
Matrix metalloproteinase-9 in glutamate-dependent adult brain function and dysfunction.
Topics: Animals; Brain; Brain Infarction; Cell Membrane; Glutamic Acid; Humans; Matrix Metalloproteinase 9; Nerve Degeneration; Neuronal Plasticity; Neurotoxins; Protein Transport | 2007 |
1 trial(s) available for glutamic acid and Brain Infarction
| Article | Year |
|---|---|
Neurological deterioration in acute lacunar infarctions: the role of excitatory and inhibitory neurotransmitters.
Topics: Acute Disease; Aged; Brain Infarction; Disease Progression; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neurotransmitter Agents; Predictive Value of Tests; Prognosis; Sensitivity and Specificity; Severity of Illness Index; Tomography, X-Ray Computed | 2001 |
40 other study(ies) available for glutamic acid and Brain Infarction
| Article | Year |
|---|---|
Cerebral ischemic injury is enhanced in a model of oculodentodigital dysplasia.
Topics: Animals; Astrocytes; Brain Infarction; Brain Ischemia; Cell Death; Cells, Cultured; Connexin 43; Craniofacial Abnormalities; Disease Models, Animal; Enzyme Inhibitors; Eye Abnormalities; Foot Deformities, Congenital; Gap Junctions; Glutamic Acid; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neurons; Serine; Syndactyly; Tooth Abnormalities | 2013 |
Neurodegeneration after transient brain ischemia in aged mice: beneficial effects of bilobalide.
Topics: Adenosine Triphosphate; Aging; Animals; Brain Infarction; Cyclopentanes; Disease Models, Animal; Extracellular Fluid; Female; Furans; Ginkgolides; Glucose; Glutamic Acid; Infarction, Middle Cerebral Artery; Locomotion; Mice; Microdialysis; Mitochondria; Multienzyme Complexes; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Phosphorylation | 2013 |
Plasma levels of neuron specific enolase quantify the extent of neuronal injury in murine models of ischemic stroke and multiple sclerosis.
Topics: Amyloid beta-Protein Precursor; Animals; Brain; Brain Infarction; Cells, Cultured; Disease Models, Animal; Embryo, Mammalian; Glutamic Acid; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Magnetic Resonance Imaging; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Multiple Sclerosis; Myelin-Oligodendrocyte Glycoprotein; Neurons; Peptide Fragments; Phosphopyruvate Hydratase; Time Factors | 2013 |
Ischemic tolerance in an in vivo model of glutamate preconditioning.
Topics: Age Factors; Analysis of Variance; Animals; Brain; Brain Edema; Brain Infarction; Brain Ischemia; Disease Models, Animal; Drug Administration Schedule; Gene Expression Regulation; Glutamate Dehydrogenase; Glutamic Acid; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Neuroprotective Agents; Proteasome Endopeptidase Complex; Receptors, Glutamate; Ubiquitin | 2015 |
7,8-Dihydroxy-4-methylcoumarin provides neuroprotection by increasing hippocalcin expression.
Topics: Animals; Antioxidants; Brain Infarction; Cell Death; Cell Line; Cell Survival; Coumarins; Dose-Response Relationship, Drug; Glutamic Acid; Hippocalcin; Hippocampus; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2015 |
In vitro and in vivo efficacy of a potent opioid receptor agonist, biphalin, compared to subtype-selective opioid receptor agonists for stroke treatment.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Brain Edema; Brain Infarction; Brain Ischemia; Cells, Cultured; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glutamic Acid; Ischemia; Motor Activity; Neurons; Neuroprotective Agents; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reperfusion Injury; Severity of Illness Index; Stroke | 2015 |
Pertussis toxin reduces calcium influx to protect ischemic stroke in a middle cerebral artery occlusion model.
Topics: Animals; Apoptosis; Brain; Brain Infarction; Calcium; Caspase 3; Cells, Cultured; Cerebral Cortex; Cerebrovascular Circulation; Disease Models, Animal; Glutamic Acid; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Neurons; Pertussis Toxin; Stroke | 2015 |
Tubastatin A, an HDAC6 inhibitor, alleviates stroke-induced brain infarction and functional deficits: potential roles of α-tubulin acetylation and FGF-21 up-regulation.
Topics: Acetylation; Animals; Brain Infarction; Cell Death; Disease Models, Animal; Fibroblast Growth Factors; Gene Expression Regulation; Glutamic Acid; Histone Deacetylase Inhibitors; Hydroxamic Acids; Indoles; Mitochondria; Neurites; Neurons; Neuroprotective Agents; Rats; Recovery of Function; Signal Transduction; Tubulin; Up-Regulation | 2016 |
Neurotrophic and neuroprotective effects of oxyntomodulin in neuronal cells and a rat model of stroke.
Topics: Animals; Brain Infarction; Cell Line, Tumor; Cell Proliferation; CREB-Binding Protein; Cyclic AMP; Disease Models, Animal; Enzyme Inhibitors; Glutamic Acid; Humans; Hydrogen Peroxide; Infarction, Middle Cerebral Artery; Locomotion; Male; Nerve Growth Factors; Neurons; Neuroprotective Agents; Oxyntomodulin; Rats; Rats, Sprague-Dawley; Signal Transduction; Stroke | 2017 |
GluR6-containing KA receptor mediates the activation of p38 MAP kinase in rat hippocampal CA1 region during brain ischemia injury.
Topics: Animals; Brain Infarction; Cell Survival; Disease Models, Animal; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; GluK2 Kainate Receptor; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Intracellular Signaling Peptides and Proteins; Male; MAP Kinase Kinase 3; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinase Kinase 11; Oligodeoxyribonucleotides, Antisense; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Reperfusion Injury; Synaptic Transmission | 2009 |
Reduced early hypoxic/ischemic brain damage is associated with increased GLT-1 levels in mice expressing mutant (P301L) human tau.
Topics: Amino Acid Sequence; Animals; Apoptosis; Brain Infarction; Calpain; Caspase 3; Cytoprotection; Excitatory Amino Acid Transporter 2; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Degeneration; Organ Culture Techniques; tau Proteins; Up-Regulation | 2009 |
The beta-lactam antibiotic, ceftriaxone, dramatically improves survival, increases glutamate uptake and induces neurotrophins in stroke.
Topics: Animals; Anti-Bacterial Agents; Body Temperature; Brain; Brain Infarction; Ceftriaxone; Cerebrovascular Disorders; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Glutamic Acid; Interleukin-6; Male; Nerve Growth Factors; Rats; Rats, Wistar; Regional Blood Flow; RNA, Messenger; Stroke; Survival Rate | 2008 |
Neuroprotective effect of memantine combined with topiramate in hypoxic-ischemic brain injury.
Topics: Animals; Animals, Newborn; Anticonvulsants; Apoptosis; Brain; Brain Infarction; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; Fructose; Glutamic Acid; Hypoxia-Ischemia, Brain; In Situ Nick-End Labeling; Male; Memantine; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Topiramate; Treatment Outcome | 2009 |
GIF-0173 protects against cerebral infarction through DP1 receptor activation.
Topics: Animals; Brain Infarction; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Cerebrovascular Circulation; Dantrolene; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Hydantoins; Infarction, Middle Cerebral Artery; Intracellular Fluid; Lactones; Laser-Doppler Flowmetry; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; Platelet Aggregation Inhibitors; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Immunologic; Receptors, Prostaglandin; Sesquiterpenes; Severity of Illness Index; Tetrazolium Salts | 2009 |
Prevention of Glutamate Accumulation and Upregulation of Phospho-Akt may Account for Neuroprotection Afforded by Bergamot Essential Oil against Brain Injury Induced by Focal Cerebral Ischemia in Rat.
Topics: Animals; Brain Infarction; Brain Ischemia; Glutamic Acid; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Oils, Volatile; Plant Oils; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Up-Regulation | 2009 |
Nitroxyl exacerbates ischemic cerebral injury and oxidative neurotoxicity.
Topics: Animals; Blood Pressure; Brain Infarction; Cells, Cultured; Dinoprost; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme-Linked Immunosorbent Assay; F2-Isoprostanes; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Mice; Mice, Inbred C57BL; Neuroglia; Neurons; Neuroprotective Agents; Nitrites; Nitrogen Oxides; Oxidative Stress; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Adenosine A 2A receptor deficiency reduces striatal glutamate outflow and attenuates brain injury induced by transient focal cerebral ischemia in mice.
Topics: Adenosine; Animals; Brain Chemistry; Brain Infarction; Brain Ischemia; Corpus Striatum; Disease Models, Animal; Down-Regulation; Extracellular Fluid; Gene Expression Regulation; Genetic Predisposition to Disease; Glutamic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Receptor, Adenosine A2A; Up-Regulation | 2009 |
Aberrant modulation of a delayed rectifier potassium channel by glutamate in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain Infarction; Cell Membrane; Cell Proliferation; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Ion Channel Gating; Kv1.3 Potassium Channel; Lymphocyte Activation; Male; Membrane Potentials; Mitogens; Neuroimmunomodulation; Patch-Clamp Techniques; Phytohemagglutinins; Receptors, Metabotropic Glutamate; T-Lymphocytes | 2010 |
Neuroprotective effects of resveratrol on ischemic injury mediated by modulating the release of neurotransmitter and neuromodulator in rats.
Topics: Animals; Antioxidants; Brain; Brain Infarction; Disease Models, Animal; Ethanolamines; Excitatory Postsynaptic Potentials; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hypothalamus; Hypoxia-Ischemia, Brain; Infarction, Middle Cerebral Artery; Inhibitory Postsynaptic Potentials; Male; Neuroprotective Agents; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Treatment Outcome | 2010 |
Pre-ischemic treadmill training induces tolerance to brain ischemia: involvement of glutamate and ERK1/2.
Topics: Animals; Behavior, Animal; Brain Infarction; Brain Ischemia; Exercise Test; Glutamic Acid; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neostriatum; Phosphorylation; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley | 2010 |
Pyruvate's blood glutamate scavenging activity contributes to the spectrum of its neuroprotective mechanisms in a rat model of stroke.
Topics: Animals; Aspartate Aminotransferases; Brain Edema; Brain Infarction; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Infarction, Middle Cerebral Artery; Male; Motor Activity; Neurologic Examination; Neuroprotective Agents; Oxaloacetic Acid; Pyruvic Acid; Random Allocation; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Time Factors | 2011 |
Selenium preserves mitochondrial function, stimulates mitochondrial biogenesis, and reduces infarct volume after focal cerebral ischemia.
Topics: Analysis of Variance; Animals; Antioxidants; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Brain Infarction; Brain Ischemia; Cell Death; Cell Line, Transformed; Disease Models, Animal; DNA Damage; Fluoresceins; Gene Expression Regulation; Glutamic Acid; Histones; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Microtubule Proteins; Mitochondria; Mitochondrial Turnover; Multienzyme Complexes; Nerve Tissue Proteins; Organic Chemicals; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Reactive Oxygen Species; Selenium; Time Factors; Trans-Activators; Transcription Factors | 2012 |
Transient lack of glucose but not O2 is involved in ischemic postconditioning-induced neuroprotection.
Topics: Animals; Brain Infarction; Chromatography, High Pressure Liquid; Disease Models, Animal; gamma-Aminobutyric Acid; Glucose; Glutamate-Ammonia Ligase; Glutamic Acid; Hypoxia; In Vitro Techniques; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Reperfusion; Time Factors | 2013 |
Neuroprotective effects of aspirin in patients with acute cerebral infarction.
Topics: Acute Disease; Aged; Aspirin; Brain Infarction; Confidence Intervals; Glutamic Acid; Humans; Middle Aged; Neuroprotective Agents; Odds Ratio | 2003 |
Acute effects of 17beta-estradiol on the extracellular concentration of excitatory amino acids and energy metabolites during transient cerebral ischemia in male rats.
Topics: Analysis of Variance; Animals; Aspartic Acid; Brain Infarction; Chromatography, High Pressure Liquid; Disease Models, Animal; Electrochemistry; Energy Metabolism; Estradiol; Excitatory Amino Acids; Extracellular Space; Glucose; Glutamic Acid; Ischemic Attack, Transient; Male; Microdialysis; Rats; Rats, Wistar; Reperfusion; Time Factors | 2004 |
Minocycline inhibits oxidative stress and decreases in vitro and in vivo ischemic neuronal damage.
Topics: Animals; Antioxidants; Benzimidazoles; Benzoxazoles; Biphenyl Compounds; Brain Edema; Brain Infarction; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Chromans; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Fluorescent Dyes; Glutamic Acid; Hydrazines; Infarction, Middle Cerebral Artery; Inhibitory Concentration 50; Ischemia; Lipid Peroxidation; Male; Mice; Minocycline; Neurons; Neuroprotective Agents; Oxidative Stress; Picrates; Quinolinium Compounds; Saponins; Tetrazolium Salts; Time Factors | 2005 |
Hypoxic-ischemic insult decreases glutamate uptake by hippocampal slices from neonatal rats: prevention by guanosine.
Topics: Analysis of Variance; Animals; Animals, Newborn; Brain Infarction; Glutamic Acid; Guanosine; Hippocampus; Hypoxia-Ischemia, Brain; In Vitro Techniques; Rats; Rats, Wistar; Time Factors | 2005 |
Prenatal hypoxia impairs memory function but does not result in overt structural alterations in the postnatal chick brain.
Topics: Animals; Brain Infarction; Chick Embryo; Chickens; Disease Models, Animal; Fetal Hypoxia; Glutamate-Ammonia Ligase; Glutamic Acid; Hypoxia, Brain; Immunohistochemistry; Memory Disorders; Microscopy, Electron, Transmission; Presynaptic Terminals; Synaptic Vesicles; Synaptophysin | 2005 |
Effects of sabiporide, a specific Na+/H+ exchanger inhibitor, on neuronal cell death and brain ischemia.
Topics: Animals; Brain Infarction; Brain Ischemia; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; Glutamic Acid; Guanidines; Mice; N-Methylaspartate; Neurons; Reperfusion; Sodium-Hydrogen Exchangers; Tetrazolium Salts; Thiazoles | 2005 |
The metabolism of C-glucose by neurons and astrocytes in brain subregions following focal cerebral ischemia in rats.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Astrocytes; Brain; Brain Infarction; Brain Ischemia; Carbon Radioisotopes; Cell Communication; Cell Death; Disease Models, Animal; Down-Regulation; Energy Metabolism; Glucose; Glutamic Acid; Glutamine; Infarction, Middle Cerebral Artery; Male; Neurons; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2006 |
Glutamate transporters GLAST and EAAT4 regulate postischemic Purkinje cell death: an in vivo study using a cardiac arrest model in mice lacking GLAST or EAAT4.
Topics: Animals; Brain Infarction; Cell Death; Disease Models, Animal; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 4; Glutamic Acid; Heart Arrest; Heart Arrest, Induced; Hypoxia-Ischemia, Brain; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Purkinje Cells | 2006 |
Estradiol prevents the injury-induced decrease of Akt/glycogen synthase kinase 3beta phosphorylation.
Topics: Animals; Apoptosis; Blotting, Western; Brain; Brain Infarction; Cell Line; Enzyme Activation; Estradiol; Female; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Immunohistochemistry; In Situ Nick-End Labeling; In Vitro Techniques; Infarction, Middle Cerebral Artery; Neuroprotective Agents; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley | 2006 |
Factors influencing cell fate in the infarct rim.
Topics: Animals; Brain Infarction; Cations, Monovalent; Cell Death; Cell Hypoxia; Culture Media; Extracellular Fluid; Glucose; Glutamic Acid; Hippocampus; Hydrogen-Ion Concentration; Ischemic Attack, Transient; Mice; Organ Culture Techniques; Oxygen; Potassium; Sodium; Temperature | 2007 |
Profile of glutamate uptake and cellular viability in hippocampal slices exposed to oxygen and glucose deprivation: developmental aspects and protection by guanosine.
Topics: Aging; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Biological Transport, Active; Brain Infarction; Cell Survival; Energy Metabolism; Glutamic Acid; Guanosine; Hippocampus; Hypoxia-Ischemia, Brain; Male; Neurons; Neuroprotective Agents; Organ Culture Techniques; Rats; Rats, Wistar | 2008 |
Downregulation of glutamate transporters is associated with elevation in extracellular glutamate concentration following rat microsphere embolism.
Topics: Animals; Brain; Brain Infarction; Brain Ischemia; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Extracellular Fluid; Glial Fibrillary Acidic Protein; Glutamic Acid; Intracranial Embolism; Male; Microdialysis; Microspheres; Microtubule-Associated Proteins; Nerve Degeneration; Neuroglia; Neurons; Potassium Chloride; Rats; Rats, Wistar; Up-Regulation | 2008 |
Dimemorfan protects rats against ischemic stroke through activation of sigma-1 receptor-mediated mechanisms by decreasing glutamate accumulation.
Topics: Analysis of Variance; Animals; Brain Infarction; Brain Ischemia; Chemokine CCL2; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Glutamic Acid; Lipid Peroxidation; Male; Morphinans; Morpholines; NF-kappaB-Inducing Kinase; Nitric Oxide Synthase; Peroxidase; Protein Serine-Threonine Kinases; Rats; Rats, Long-Evans; Receptors, sigma; Reperfusion Injury; Sigma-1 Receptor; Signal Transduction; STAT1 Transcription Factor | 2008 |
DCPIB, a specific inhibitor of volume regulated anion channels (VRACs), reduces infarct size in MCAo and the release of glutamate in the ischemic cortical penumbra.
Topics: Animals; Aspartic Acid; Brain Infarction; Chromatography, High Pressure Liquid; Cyclopentanes; Dialysis; Disease Models, Animal; Drug Administration Routes; Fluorenes; Glutamic Acid; Indans; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Tetrazolium Salts | 2008 |
Inhibited glutamate release by granulocyte-colony stimulating factor after experimental stroke.
Topics: Animals; Brain Infarction; Corpus Striatum; Disease Models, Animal; Glutamic Acid; Granulocyte Colony-Stimulating Factor; Infarction, Middle Cerebral Artery; Male; Rats; Rats, Wistar; Time Factors | 2008 |
Post-ischemic administration of DY-9760e, a novel calmodulin antagonist, reduced infarct volume in the permanent focal ischemia model of spontaneously hypertensive rat.
Topics: Animals; Brain Infarction; Brain Ischemia; Calcium; Calmodulin; Cerebral Cortex; Cerebrovascular Circulation; Disease Models, Animal; Glutamic Acid; Indazoles; Male; Neostriatum; Nerve Degeneration; Neuroprotective Agents; Rats; Rats, Inbred SHR | 2001 |
Inflammation-mediated damage in progressing lacunar infarctions: a potential therapeutic target.
Topics: Aged; Biomarkers; Brain Infarction; Disease Progression; Encephalitis; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Intercellular Adhesion Molecule-1; Interleukin-6; Logistic Models; Male; Middle Aged; Odds Ratio; Predictive Value of Tests; Prognosis; Severity of Illness Index; Tumor Necrosis Factor-alpha | 2002 |