glutamic acid has been researched along with Blood Pressure, High in 113 studies
Timeframe | Studies, this research(%) | All Research% |
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pre-1990 | 10 (8.85) | 18.7374 |
1990's | 27 (23.89) | 18.2507 |
2000's | 44 (38.94) | 29.6817 |
2010's | 24 (21.24) | 24.3611 |
2020's | 8 (7.08) | 2.80 |
Authors | Studies |
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Chen, F; Chu, D; Du, D; Tong, L; Wu, J; Xing, M; Zhang, H; Zhang, S | 1 |
Lecarpentier, Y; Vallée, A; Vallée, JN | 1 |
Fan, JF; Li, JK; Li, WY; Niu, LY; Tan, X; Wang, W; Wang, WZ; Wang, YK; Ye, P | 1 |
Dupont, AG; Légat, L; Smolders, I | 1 |
Hébert, JL; Lecarpentier, Y; Schussler, O; Vallée, A | 1 |
Haibara, AS; Katsurada, K; Liu, X; Nandi, SS; Patel, KP; Sharma, NM; Zheng, H | 1 |
Contoreggi, NH; Glass, MJ; Marques-Lopes, J; Milner, TA; Pickel, VM; Wang, G; Woods, C | 1 |
Chen, SL; Chu, CH; Liu, YC; Yen, PS | 1 |
Cai, D; Yu, B | 1 |
Li, DP; Pan, HL | 2 |
Chen, YT; Lin, XM; Shen, PP; Xiao, SK; Yang, YY; Yao, W | 1 |
Li, CB; Ren, CZ; Shi, XY; Tan, X; Wang, W; Wang, WZ; Yao, XY; Zhang, RW; Zou, Z | 1 |
Farnham, MMJ; Kakall, ZM; Pilowsky, PM | 1 |
Blanch, GT; Colombari, E; de Mello, ABS; Dos Santos Moreira, MC; Freiria-Oliveira, AH; Gomes, RM; Lopes, PR; Mourão, AA; Pedrino, GR; Rodrigues, KL; Xavier, CH | 1 |
Chen, H; Chen, SR; Li, DP; Ma, H; Pan, HL; Zhou, JJ | 1 |
Dampney, RA; Li, DP; Michelini, LC; Pan, HL | 1 |
Basting, T; Epling, J; Fuchs, R; Lazartigues, E; Mukerjee, S; Sriramula, S; Xu, J | 1 |
Kalinina, TS; Kiselev, AV; Stovbun, SV; Vostrikova, EV | 1 |
Gabor, A; Leenen, FH | 1 |
Deng, XM; Deng, Y; Tan, X; Wang, WZ; Wang, YK; Yuan, WJ; Zha, YP; Zhang, RW | 1 |
Li, DP; Pan, HL; Ye, ZY | 1 |
Kang, YM; Qi, J; Qin, DN; Su, Q; Suo, YP; Yang, Q; Yu, XJ; Yue, LY; Zhang, DM; Zhu, GQ | 1 |
Jia, LL; Kang, YM; Li, HB; Qi, J; Qin, DN; Suo, YP; Tian, ZJ; Wang, FX; Yu, XJ; Zhang, Y; Zhu, GQ; Zhu, Z | 1 |
Chen, YF; Deng, Y; Hao, Q; Hu, QK; Shen, D; Su, DF; Wang, WZ; Wang, YK; Wu, ZT; Yu, Q; Yuan, WJ | 1 |
Iwasa, M; Kawabe, K; Kawabe, T; Sapru, HN | 1 |
Arós, F; Clish, CB; Corella, D; Dennis, C; Estruch, R; Fiol, M; Fitó, M; Gómez-Gracia, E; Hruby, A; Hu, FB; Lapetra, J; Liang, L; Martínez-González, MA; Ros, E; Ruiz-Canela, M; Salas-Salvado, J; Serra-Majem, L; Toledo, E; Zheng, Y | 1 |
Biancardi, VC; Patel, KP; Sharma, N; Son, S; Stern, JE; Zheng, H | 1 |
Kaetu, A; Kishimoto, T; Kotani, K; Kurosawa, Y; Okamoto, M; Osaki, Y; Sawada, T; Tahara, A | 1 |
Hirayama, A; Ito, S; Komatsu, K; Matsumoto, K; Tsukamoto, K; Yajima, Y | 1 |
Brown, IJ; Chan, Q; Daviglus, ML; Elliott, P; Kesteloot, H; Stamler, J; Ueshima, H; Zhao, L | 1 |
Mifflin, S; Zhang, W | 1 |
Gallinat, J; Joppke, M; Klär, AA; Schubert, F; Westhoff, TH; Wirth, C; Zidek, W | 1 |
Makani, H; Messerli, FH | 1 |
Huber, DA; Schreihofer, AM | 1 |
Osborn, JW; Veitenheimer, B | 1 |
Coote, JH; Yang, Z | 1 |
Guyenet, PG; Sevigny, CP; Stornetta, RL; Wang, H; Weston, M | 1 |
Hirooka, Y; Ito, K; Kishi, T; Sakai, K; Shimokawa, H; Takeshita, A | 1 |
Ito, S; Kanmatsuse, K; Katsunuma, N; Tsukamoto, K | 1 |
Russell, VA | 1 |
RIZKALLA, Y | 1 |
Ku, YH; Li, YH | 2 |
Al-Sarraf, H; Philip, L | 1 |
Dragon, DN; Talman, WT | 1 |
Hirooka, Y; Ito, K; Kimura, Y; Kishi, T; Shimokawa, H; Takeshita, A | 1 |
Kellaway, L; Lehohla, M; Russell, VA | 1 |
Harada, S; Kido, H; Morimoto, S; Nakagawa, M; Oguni, A; Sasaki, S; Takeda, K | 1 |
Farfel, Z; Holtzman, EJ; Mayan, H; Mouallem, M; Munter, G; Pauzner, R; Shaharabany, M | 1 |
Isogai, O; Ito, S; Kanmatsuse, K; Kasamaki, Y; Kawato, H; Masubuchi, Y; Suzuki, T; Tomioka, S; Tsukamoto, K; Yajima, Y | 1 |
Eriksson, AL; Hedner, T; Ohlsson, C; Wallerstedt, SM | 1 |
Arcucci, O; Cipolletta, E; De Luca, N; Di Renzo, G; Iaccarino, G; Izzo, R; Lanni, F; Trimarco, V | 1 |
Corrêa, FM; Pajolla, GP; Pelosi, GG | 1 |
Jensen, GB; Nordestgaard, BG; Sethi, AA; Tybjaerg-Hansen, A | 1 |
Basso, LS; Becker, LK; de Souza, HC; Garcia, MR; Lopes, OU; Martins-Pinge, MC; Neto, RV; Zoccal, DB | 1 |
Fujii, K; Fukuhara, M; Iida, M; Kagiyama, S; Lin, Y; Matsumura, K | 1 |
Chang, CP; Chen, SH; Lin, MT | 1 |
Chen, R; Chen, S; Ge, D; Gu, D; Huang, J; Li, B; Qiang, B; Su, S | 1 |
Feng, YQ; Li, JS; Wang, H; Zhang, HJ | 1 |
Amar, J; Baguet, JP; Cambien, F; Chamontin, B; François, P; Mallion, JM; Mounier Vehier, C; Ormezzano, O; Poirier, O | 1 |
Dai, XP; Li, HH; Liu, J; Liu, ZQ; Mo, W; Tan, YM; Yang, TL; Zeng, H; Zhang, GG; Zhou, HH | 1 |
Ferrari, MF; Fior-Chadi, DR | 1 |
Catone, C; Chazalviel, L; Chuquet, J; Lecrux, C; MacKenzie, ET; Nicole, O; Touzani, O | 1 |
Das, N; Das, S; Narang, R; Sreenivas, V; Srivastava, K | 1 |
Aicher, SA; Andresen, MC; Bailey, TW; Hermes, SM; Lynch, PJ; McKee, BL; Mitchell, JL; Silverman, MB | 1 |
Corrêa, FM; Resstel, LB | 1 |
Li, DP; Pan, HL; Pan, HM; Yang, Q | 1 |
Blessing, WW; Reis, DJ; Sved, AF | 1 |
Granata, AR; Reis, DJ; Talman, WT | 1 |
Head, RA; Tunnicliff, G; Welborn, KL | 1 |
Misu, Y; Miyamae, T; Okumura, Y; Ueda, H; Yue, JL | 1 |
Chai, CY; Yang, TL; Yen, CT | 1 |
Campos, RR; Cravo, SL; Guertzenstein, PG; Lopes, OU; Possas, OS | 1 |
Calaresu, FR; Cogo, CE; Ermirio, R; Picchio, V; Ruggeri, P | 1 |
Sved, AF; Tsukamoto, K | 1 |
Gordon, FJ; Pawloski-Dahm, CM | 1 |
Douglas, FL; Melethil, S; Rakhit, A; Tang, JP; Xu, ZQ | 1 |
Goldstein, M; Masuyama, Y; Nishio, I; Tsuda, K; Tsuda, S | 2 |
Berrino, L; D'Amico, M; de Novellis, V; Pizzirusso, A; Rossi, F | 1 |
Chalmers, JP; Kapoor, R; Kapoor, V | 1 |
Misu, Y; Miyamae, T; Ueda, H; Yue, JL | 1 |
Arnolda, L; Chalmers, J; Hara, K; Llewellyn-Smith, I; Minson, J; Miyawaki, T; Pilowsky, P | 1 |
Abe, I; Fujishima, M; Kagiyama, S; Ohya, Y; Tsuchihashi, T | 1 |
Kobayashi, M; Yokogoshi, H | 1 |
Eshima, K; Hirooka, Y; Hori, N; Shihara, M; Takeshita, A | 1 |
Baima, J; Baldwin, CT; Bresnahan, M; Burzstyn, M; DeStefano, AL; Farrer, L; Gavras, H; Gavras, I; Handy, DE; Joost, O; Manolis, A; Martel, T; Nicolaou, M; Schwartz, F | 1 |
Bergamaschi, CT; Campos, RR; Lopes, OU | 1 |
Ito, S; Komatsu, K; Sved, AF; Tsukamoto, K | 1 |
Dreshaj, IA; Ernsberger, P; Haxhiu, MA; Tolentino-Silva, FP; Waldbaum, S | 2 |
Abe, I; Fujishima, M; Kagiyama, S; Lin, Y; Matsumura, K; Tsuchihashi, T | 1 |
Bengtsson, K; Groop, L; Lindblad, U; Melander, O; Orho-Melander, M; Ranstam, J; Råstam, L | 1 |
Goodchild, AK; Pilowsky, PM; Seyedabadi, M | 1 |
Benjafield, AV; Ericsson, JO; Morris, BJ | 1 |
Ikäheimo, M; Karvonen, J; Kauma, H; Kervinen, K; Kesäniemi, YA; Päivänsalo, M; Rantala, M; Savolainen, MJ | 1 |
Dambinova, SA; Khounteev, GA; Skoromets, AA | 1 |
Miura, M; Takayama, K | 2 |
Fujishima, M; Hirano, M; Matsumoto, T; Ooboshi, H; Sadoshima, S; Uchimura, H; Yao, H | 1 |
Krieger, AJ; Maeda, M; Sapru, HN | 1 |
Hayashi, J; Hirata, M; Itoh, H; Kawasaki, S; Nakagawa, M; Nakata, T; Oguro, M; Sasaki, S; Takeda, K; Tanaka, M | 1 |
Lewis, SJ; Talman, WT | 1 |
Barron, KW; Smith, JK | 2 |
Arnerić, SP; Tingley, FD | 1 |
Harano, K; Harano, T; Imai, K; Ohkushi, T; Ueda, S | 1 |
Berecek, KH; Hofbauer, KG; Mah, SC; Olpe, HR | 1 |
Buckley, JP; Chelly, JE; Doursout, MF | 1 |
Nelson, DO | 1 |
Angrisani, M; Berrino, L; De Santis, D; Fici, F; Lampa, E; Maione, S; Marmo, E; Marrazzo, R; Susanna, V | 1 |
Brody, MJ; Machado, BH | 1 |
4 review(s) available for glutamic acid and Blood Pressure, High
Article | Year |
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WNT/β-catenin Pathway: a Possible Link Between Hypertension and Alzheimer's Disease.
Topics: Aged; Alzheimer Disease; beta Catenin; Essential Hypertension; Glutamic Acid; Humans; Hypertension; Wnt Signaling Pathway | 2022 |
Molecular Mechanisms Underlying the Circadian Rhythm of Blood Pressure in Normotensive Subjects.
Topics: Animals; Blood Pressure; Circadian Rhythm; Glutamic Acid; Humans; Hypertension; Suprachiasmatic Nucleus | 2020 |
Glutamatergic Regulation of Hypothalamic Presympathetic Neurons in Hypertension.
Topics: Animals; Glutamic Acid; Humans; Hypertension; Hypothalamus; Neuronal Plasticity; Neurons; Paraventricular Hypothalamic Nucleus; Rats; Receptors, Glutamate; Sympathetic Nervous System | 2017 |
Regulation of sympathetic vasomotor activity by the hypothalamic paraventricular nucleus in normotensive and hypertensive states.
Topics: Angiotensin II; Animals; Blood Pressure; Blood-Brain Barrier; Cardiovascular System; Disease Models, Animal; Excitatory Postsynaptic Potentials; Exercise Therapy; GABAergic Neurons; Glutamic Acid; Humans; Hypertension; Inflammation Mediators; Neural Inhibition; Oxidative Stress; Paraventricular Hypothalamic Nucleus; Synaptic Transmission; Vasomotor System | 2018 |
1 trial(s) available for glutamic acid and Blood Pressure, High
Article | Year |
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[A randomized, double-blind, placebo-controlled study of the efficacy and safety of ampasse in the treatment of chronic cerebral ischemia].
Topics: Aged; Brain Ischemia; Chronic Disease; Depressive Disorder; Double-Blind Method; Glutamic Acid; Humans; Hypertension; Middle Aged; Treatment Outcome | 2019 |
108 other study(ies) available for glutamic acid and Blood Pressure, High
Article | Year |
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Overexpression of NaV1.6 in the rostral ventrolateral medulla in rats mediates stress-induced hypertension via glutamate regulation.
Topics: Animals; Blood Pressure; Glutamic Acid; Hypertension; Medulla Oblongata; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System | 2022 |
Contribution of cyclooxygenase-2 overexpression to enhancement in tonically active glutamatergic inputs to the rostral ventrolateral medulla in hypertension.
Topics: Animals; Blood Pressure; Cyclooxygenase 2; Dinoprostone; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutaminase; Hypertension; Medulla Oblongata; Mice; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2022 |
Angiotensin-II-mediated AT
Topics: Angiotensin II; Animals; Blood Pressure; Down-Regulation; Glutamic Acid; Hypertension; Medulla Oblongata; N-Methylaspartate; Rats; Receptor, Angiotensin, Type 1; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2020 |
Central Ang II (Angiotensin II)-Mediated Sympathoexcitation: Role for HIF-1α (Hypoxia-Inducible Factor-1α) Facilitated Glutamatergic Tone in the Paraventricular Nucleus of the Hypothalamus.
Topics: Angiotensin II; Animals; Baroreflex; Glutamic Acid; Hypertension; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney; Male; N-Methylaspartate; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sympathetic Nervous System | 2021 |
Tumor Necrosis Factor α Receptor Type 1 Activation in the Hypothalamic Paraventricular Nucleus Contributes to Glutamate Signaling and Angiotensin II-Dependent Hypertension.
Topics: Angiotensin II; Animals; Glutamic Acid; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Paraventricular Hypothalamic Nucleus; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction | 2021 |
Upregulation of Glutamatergic Receptors in Hippocampus and Locomotor Hyperactivity in Aged Spontaneous Hypertensive Rat.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Glutamic Acid; Hippocampus; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Up-Regulation | 2022 |
Neural Programmatic Role of Leptin, TNFα, Melanocortin, and Glutamate in Blood Pressure Regulation vs Obesity-Related Hypertension in Male C57BL/6 Mice.
Topics: Animals; Blood Pressure; Brain; Glutamic Acid; Hypertension; Leptin; Male; Melanocortins; Mice; Mice, Inbred C57BL; Neurons; Obesity; Tumor Necrosis Factor-alpha | 2017 |
[Effect of Acupuncture at "Taichong"(LR 3) and "Neiguan"(PC 6) on Blood Pressure and Contents of Aspartic Acid and Glutamic Acid in the Rostral Ventrolateral Medulla in Spontaneous Hypertension Rats].
Topics: Acupuncture Points; Acupuncture Therapy; Animals; Aspartic Acid; Blood Pressure; Disease Models, Animal; Glutamic Acid; Humans; Hypertension; Male; Medulla Oblongata; Rats; Rats, Inbred SHR; Rats, Wistar | 2017 |
Enhancement in Tonically Active Glutamatergic Inputs to the Rostral Ventrolateral Medulla Contributes to Neuropathic Pain-Induced High Blood Pressure.
Topics: Animals; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutaminase; Hyperalgesia; Hypertension; Male; Medulla Oblongata; Neuralgia; Paraventricular Hypothalamic Nucleus; Periaqueductal Gray; Rats, Sprague-Dawley; Receptors, Glutamate; Sympathetic Nervous System; Vesicular Glutamate Transport Protein 2 | 2017 |
PACAP-(6-38) or kynurenate microinjections in the RVLM prevent the development of sympathetic long-term facilitation after acute intermittent hypoxia.
Topics: Acute Disease; Animals; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Hypertension; Hypoxia; Kynurenic Acid; Long-Term Potentiation; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Sleep Apnea, Obstructive; Sympathetic Nervous System; Synaptic Transmission; Time Factors | 2018 |
Median preoptic nucleus excitatory neurotransmitters in the maintenance of hypertensive state.
Topics: Angiotensin II; Animals; Disease Models, Animal; Glutamic Acid; Hypertension; Male; Preoptic Area; Rats, Inbred SHR; Rats, Wistar; Receptors, Neurotransmitter | 2018 |
α2δ-1 couples to NMDA receptors in the hypothalamus to sustain sympathetic vasomotor activity in hypertension.
Topics: Animals; Calcium Channels, L-Type; Excitatory Postsynaptic Potentials; Glutamic Acid; Hypertension; Hypothalamus; Male; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, N-Methyl-D-Aspartate; Sympathetic Nervous System | 2018 |
Glutamatergic neurons of the paraventricular nucleus are critical contributors to the development of neurogenic hypertension.
Topics: Animals; Blood Pressure; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Channelrhodopsins; Female; Gene Expression Regulation; Glucose Transporter Type 2; Glutamic Acid; Hypertension; Male; Mice; Neurons; Paraventricular Hypothalamic Nucleus | 2018 |
Central mineralocorticoid receptors and the role of angiotensin II and glutamate in the paraventricular nucleus of rats with angiotensin II-induced hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Eplerenone; Glutamic Acid; Heart Rate; Hypertension; Infusions, Intravenous; Infusions, Intraventricular; Kynurenic Acid; Male; Mineralocorticoid Receptor Antagonists; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Glutamate; Receptors, Mineralocorticoid; Signal Transduction; Spironolactone; Tetrazoles | 2013 |
Exercise training lowers the enhanced tonically active glutamatergic input to the rostral ventrolateral medulla in hypertensive rats.
Topics: Animals; Exercise Test; Glutamic Acid; Hypertension; Male; Medulla Oblongata; Physical Conditioning, Animal; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2013 |
Regulation of Hypothalamic Presympathetic Neurons and Sympathetic Outflow by Group II Metabotropic Glutamate Receptors in Spontaneously Hypertensive Rats.
Topics: Adaptation, Physiological; Animals; Cyclopropanes; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; Hypertension; Male; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Metabotropic Glutamate; Sympathetic Nervous System | 2013 |
Chronic infusion of enalaprilat into hypothalamic paraventricular nucleus attenuates angiotensin II-induced hypertension and cardiac hypertrophy by restoring neurotransmitters and cytokines.
Topics: Angiotensin II; Animals; Cardiomegaly; Chemokine CCL2; Enalaprilat; gamma-Aminobutyric Acid; Glutamic Acid; Heart; Hypertension; Interleukin-10; Interleukin-1beta; Interleukin-6; Kidney; Losartan; Male; Neurotransmitter Agents; Norepinephrine; Organ Size; Paraventricular Hypothalamic Nucleus; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2014 |
Exercise training attenuates hypertension and cardiac hypertrophy by modulating neurotransmitters and cytokines in hypothalamic paraventricular nucleus.
Topics: Animals; Arterial Pressure; Cardiomegaly; Cytokines; gamma-Aminobutyric Acid; Glutamic Acid; Hypertension; Male; NADPH Oxidases; NF-kappa B; Norepinephrine; Oxidative Stress; Paraventricular Hypothalamic Nucleus; Physical Conditioning, Animal; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System | 2014 |
Overexpression of angiotensin-converting enzyme 2 attenuates tonically active glutamatergic input to the rostral ventrolateral medulla in hypertensive rats.
Topics: Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Disease Models, Animal; Excitatory Amino Acid Antagonists; Gene Transfer Techniques; Genetic Vectors; Glutamic Acid; Green Fluorescent Proteins; Heart Rate; Humans; Hypertension; Injections; Kynurenic Acid; Lentivirus; Male; Medulla Oblongata; Norepinephrine; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Glutamate; Time Factors; Up-Regulation | 2014 |
Attenuation of angiotensin type 2 receptor function in the rostral ventrolateral medullary pressor area of the spontaneously hypertensive rat.
Topics: Angiotensin II Type 2 Receptor Blockers; Animals; Arterial Pressure; Blood Pressure; Glutamic Acid; Heart Rate; Hypertension; Imidazoles; Immunohistochemistry; Male; Medulla Oblongata; Microinjections; Neurons; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Receptor, Angiotensin, Type 2; Spinal Cord Lateral Horn; Splanchnic Nerves | 2016 |
Metabolites of Glutamate Metabolism Are Associated With Incident Cardiovascular Events in the PREDIMED PREvención con DIeta MEDiterránea (PREDIMED) Trial.
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Diet, Mediterranean; Dyslipidemias; Female; Glutamic Acid; Glutamine; Humans; Hypertension; Incidence; Male; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Randomized Controlled Trials as Topic; Risk Factors; Smoking; Spain; Stroke; Tobacco Smoking | 2016 |
Astrocytes Contribute to Angiotensin II Stimulation of Hypothalamic Neuronal Activity and Sympathetic Outflow.
Topics: Angiotensin II; Animals; Astrocytes; Blotting, Western; Cells, Cultured; Electrophysiology; Glutamic Acid; Hypertension; Male; Neurons; Paraventricular Hypothalamic Nucleus; Rats; Sympathetic Nervous System | 2016 |
Relation of the Glu298Asp polymorphism of the nitric oxide synthase gene to hypertension and serum cholesterol in Japanese workers.
Topics: Adult; Aged; Cholesterol; Female; Glutamic Acid; Humans; Hypertension; Japan; Male; Middle Aged; Nitric Oxide Synthase Type III; Odds Ratio; Polymorphism, Genetic; Sequence Analysis, DNA | 2008 |
Enhanced response from the caudal pressor area in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Glutamic Acid; Glycine; Glycine Agents; Heart Rate; Hypertension; Male; Medulla Oblongata; Microinjections; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity; Sympathetic Nervous System | 2008 |
Glutamic acid, the main dietary amino acid, and blood pressure: the INTERMAP Study (International Collaborative Study of Macronutrients, Micronutrients and Blood Pressure).
Topics: Adult; Amino Acids; Blood Pressure; Cooperative Behavior; Cross-Sectional Studies; Dietary Proteins; Female; Glutamic Acid; Humans; Hypertension; Internationality; Male; Micronutrients; Middle Aged | 2009 |
Chronic hypertension enhances presynaptic inhibition by baclofen in the nucleus of the solitary tract.
Topics: Animals; Baclofen; Baroreflex; Chronic Disease; Disease Models, Animal; GABA Agonists; Glutamic Acid; Hypertension; Male; Neurons; Pressoreceptors; Presynaptic Terminals; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Solitary Nucleus; Synaptic Potentials; Synaptic Transmission | 2010 |
The impact of blood pressure on hippocampal glutamate and mnestic function.
Topics: Adult; Aspartic Acid; Blood Pressure; Cognition; Cognition Disorders; Female; Germany; Glutamic Acid; Gyrus Cinguli; Hippocampus; Humans; Hypertension; Linear Models; Magnetic Resonance Spectroscopy; Male; Memory; Middle Aged; Neuropsychological Tests; Young Adult | 2011 |
Does glutamic acid lower blood pressure?
Topics: Blood Pressure; Dietary Proteins; Glutamic Acid; Humans; Hypertension; Randomized Controlled Trials as Topic; Treatment Outcome | 2010 |
Altered regulation of the rostral ventrolateral medulla in hypertensive obese Zucker rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Brain Stem; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Heart Rate; Hypertension; Losartan; Medulla Oblongata; Microinjections; Muscle Tonus; Muscle, Smooth, Vascular; Obesity; Rats; Rats, Zucker; Receptors, GABA-A; Splanchnic Circulation; Sympathetic Nervous System | 2011 |
Effects of intrathecal kynurenate on arterial pressure during chronic osmotic stress in conscious rats.
Topics: Animals; Antihypertensive Agents; Arterial Pressure; Blood Pressure Monitoring, Ambulatory; Consciousness; Desoxycorticosterone; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Hypertension; Injections, Spinal; Kynurenic Acid; Male; Osmolar Concentration; Osmotic Pressure; Rats; Rats, Sprague-Dawley; Receptors, Ionotropic Glutamate; Spinal Cord; Stress, Physiological; Telemetry; Time Factors; Water Deprivation | 2013 |
The influence of vasopressin on tonic activity of cardiovascular neurones in the ventrolateral medulla of the hypertensive rat.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Cardiovascular System; Glutamic Acid; Hypertension; Iontophoresis; Medulla Oblongata; Neurons; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred SHR; Rats, Wistar; Sympathetic Nervous System; Vasoconstrictor Agents; Vasomotor System; Vasopressins | 2003 |
Fos expression by glutamatergic neurons of the solitary tract nucleus after phenylephrine-induced hypertension in rats.
Topics: Animals; Baroreflex; Carrier Proteins; Cell Count; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Hypertension; Isoenzymes; Male; Medulla Oblongata; Membrane Transport Proteins; Neurons; Phenylephrine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Sympathomimetics; Vasoconstrictor Agents; Vesicular Glutamate Transport Protein 2; Vesicular Transport Proteins | 2003 |
Enhanced depressor response to endothelial nitric oxide synthase gene transfer into the nucleus tractus solitarii of spontaneously hypertensive rats.
Topics: Animals; beta-Galactosidase; Blood Pressure; Cisterna Magna; Enzyme Inhibitors; Gene Transfer Techniques; Genetic Therapy; Glutamic Acid; Heart Rate; Hypertension; Male; Microinjections; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Solitary Nucleus; Telemetry | 2003 |
Enhanced angiotensin-mediated responses in the nucleus tractus solitarii of spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensins; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Interactions; Functional Laterality; Glutamic Acid; Heart Rate; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Solitary Nucleus; Species Specificity; Tetrazoles; Valine; Valsartan | 2003 |
In vitro glutamate-stimulated release of dopamine from nucleus accumbens core and shell of spontaneously hypertensive rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dopamine; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypertension; In Vitro Techniques; Nucleus Accumbens; Perfusion; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, AMPA | 2003 |
Glutamic acid in the treatment of cerebral arteriosclerosis and some cases of hypertension.
Topics: Arteriosclerosis; Glutamates; Glutamic Acid; Humans; Hypertension; Intracranial Arteriosclerosis; Vascular Diseases | 1955 |
Subfornical organ-angiotensin II pressor system takes part in pressor response of emotional circuit.
Topics: Amygdala; Angiotensin II; Animals; Blood Pressure; Brain; Glutamic Acid; Heart Rate; Histocytochemistry; Hypertension; Hypothalamic Area, Lateral; Intralaminar Thalamic Nuclei; Male; Microinjections; Models, Neurological; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Stress, Psychological; Subfornical Organ | 2003 |
Increased brain uptake and CSF clearance of 14C-glutamate in spontaneously hypertensive rats.
Topics: Animals; Biological Transport; Blood Pressure; Blood-Brain Barrier; Brain; Carbon Isotopes; Cerebrospinal Fluid; Cerebrovascular Circulation; Disease Models, Animal; Female; Glutamic Acid; Hypertension; Kinetics; Male; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2003 |
Transmission of arterial baroreflex signals depends on neuronal nitric oxide synthase.
Topics: Amidines; Animals; Baroreflex; Blood Pressure; Enzyme Inhibitors; Glutamic Acid; Heart Rate; Hypertension; Injections; Male; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Reflex, Abnormal; Signal Transduction; Solitary Nucleus; Synaptic Transmission; Thiophenes | 2004 |
Increased reactive oxygen species in rostral ventrolateral medulla contribute to neural mechanisms of hypertension in stroke-prone spontaneously hypertensive rats.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Animals; Blood Pressure; Brain Chemistry; Catalase; Cyclic N-Oxides; Deferoxamine; Genetic Predisposition to Disease; Genetic Therapy; Glutamic Acid; Hydrogen Peroxide; Hydroxyl Radical; Hypertension; Lipid Peroxidation; Male; Medulla Oblongata; Norepinephrine; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Recombinant Fusion Proteins; Spin Labels; Stroke; Superoxide Dismutase; Superoxides; Sympathetic Nervous System; Thiobarbituric Acid Reactive Substances; Transduction, Genetic; Vasomotor System | 2004 |
NMDA receptor function in the prefrontal cortex of a rat model for attention-deficit hyperactivity disorder.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Calcium; Disease Models, Animal; Glutamic Acid; Hypertension; Male; Prefrontal Cortex; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, N-Methyl-D-Aspartate | 2004 |
Effects of angiotensin II type 1 receptor antagonist on pressor responses to pulsatile compression of the rostral ventrolateral medulla in rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypertension; Imidazoles; Injections, Intravenous; Kynurenic Acid; Male; Medulla Oblongata; Pulsatile Flow; Pyridines; Rats; Rats, Wistar; Sympathetic Nervous System; Tetrazoles; Vasoconstrictor Agents | 2004 |
Hypercalciuria in familial hyperkalemia and hypertension accompanies hyperkalemia and precedes hypertension: description of a large family with the Q565E WNK4 mutation.
Topics: Adult; Calcium; Calcium Metabolism Disorders; Female; Glutamic Acid; Glutamine; Humans; Hyperkalemia; Hypertension; Male; Middle Aged; Mutation; Pedigree; Protein Serine-Threonine Kinases | 2004 |
High salt diet enhances cardiovascular responses from the nucleus tractus solitarius and ventrolateral medulla of Sprague-Dawley rats.
Topics: Acetylcholine; Animals; Baroreflex; Blood Pressure; Drug Synergism; Glutamic Acid; Heart Rate; Hypertension; Male; Medulla Oblongata; Microinjections; Rats; Rats, Sprague-Dawley; Serotonin; Sodium Chloride, Dietary; Solitary Nucleus | 2005 |
Haplotype association analysis of the polymorphisms Arg16Gly and Gln27Glu of the adrenergic beta2 receptor in a Swedish hypertensive population.
Topics: Arginine; Blood Pressure; Cohort Studies; Female; Glutamic Acid; Glutamine; Glycine; Haplotypes; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Polymorphism, Genetic; Prospective Studies; Receptors, Adrenergic, beta-2; Sweden | 2005 |
beta-Blockade and increased dyslipidemia in patients bearing Glu27 variant of beta2 adrenergic receptor gene.
Topics: Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-3 Receptor Antagonists; Adrenergic beta-Antagonists; Alleles; Antihypertensive Agents; Arginine; Atenolol; Blood Glucose; Cholesterol; Female; Follow-Up Studies; Glutamic Acid; Homozygote; Humans; Hyperlipidemias; Hypertension; Male; Metoprolol; Polymorphism, Genetic; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3; Risk Factors; Triglycerides | 2005 |
Involvement of NMDA receptors in the hypotensive response to the injection of L-glutamate into the lateral hypothalamus of unanesthetized rats.
Topics: Analysis of Variance; Animals; Blood Pressure; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Heart Rate; Hypertension; Hypothalamic Area, Lateral; Male; Microinjections; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Wakefulness | 2005 |
164Ile allele in the beta2-Adrenergic receptor gene is associated with risk of elevated blood pressure in women. The Copenhagen City Heart Study.
Topics: Alleles; Arginine; Blood Pressure; Body Mass Index; Denmark; Female; Gene Expression Regulation; Gene Frequency; Genetic Variation; Genotype; Glutamic Acid; Glutamine; Glycine; Haplotypes; Heart Rate; Heterozygote; Humans; Hypertension; Isoleucine; Linkage Disequilibrium; Male; Receptors, Adrenergic, beta-2; Risk; Risk Factors; Sequence Analysis, DNA; Sex Factors; Time Factors | 2005 |
Attenuated pressor responses to amino acids in the rostral ventrolateral medulla after swimming training in conscious rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular System; Consciousness; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; Heart Rate; Hypertension; Hypotension; Injections, Intraventricular; Male; Medulla Oblongata; Microinjections; Physical Conditioning, Animal; Prazosin; Rats; Rats, Wistar; Swimming; Tachycardia | 2005 |
Chronic administration of olmesartan attenuates the exaggerated pressor response to glutamate in the rostral ventrolateral medulla of SHR.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Autonomic Pathways; Blood Pressure; Drug Administration Schedule; Drug Interactions; Excitatory Amino Acid Agonists; Glutamic Acid; Hypertension; Imidazoles; Male; Medulla Oblongata; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, N-Methyl-D-Aspartate; Reticular Formation; Sympathetic Nervous System; Synaptic Transmission; Tetrazoles; Treatment Outcome; Vasoconstriction | 2005 |
Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke.
Topics: Anesthesia; Animals; Brain; Brain Ischemia; Corpus Striatum; Disease Models, Animal; Glutamic Acid; Glycerol; Heat Stroke; Hot Temperature; Hypertension; Hypoxia; Intracranial Hypertension; Ketanserin; Lactates; Lactic Acid; Models, Statistical; Neurons; Oxygen; Pressure; Pyrimidines; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists; Shock; Temperature; Time Factors; Titanium; Urethane | 2005 |
Association study with 33 single-nucleotide polymorphisms in 11 candidate genes for hypertension in Chinese.
Topics: Alanine; Asian People; Case-Control Studies; Cytochrome P-450 CYP11B2; Epistasis, Genetic; Female; G-Protein-Coupled Receptor Kinase 4; Glutamic Acid; Glutamine; Humans; Hypertension; Male; Middle Aged; Polymorphism, Single Nucleotide; Protein Serine-Threonine Kinases; Receptor, Angiotensin, Type 1; Receptors, Adrenergic, beta-2; Tyrosine 3-Monooxygenase; Valine | 2006 |
Determination of aspartate and glutamate in rabbit retina using polymer monolith microextraction coupled to high-performance liquid chromatography with fluorescence detection.
Topics: Animals; Aspartic Acid; Calibration; Chromatography, High Pressure Liquid; Fluorescence; Glutamic Acid; Hydrogen-Ion Concentration; Hypertension; Molecular Structure; Polymers; Rabbits; Retina | 2006 |
Glutamatergic inputs in the hypothalamic paraventricular nucleus maintain sympathetic vasomotor tone in hypertension.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Blood Pressure; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; Heart Rate; Hypertension; Kynurenic Acid; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Pyridazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System; Vasomotor System | 2007 |
Association of eNOS Glu298Asp gene polymorphism with circadian blood pressure rhythm.
Topics: Adult; Aged; Aspartic Acid; Blood Pressure; Circadian Rhythm; Glutamic Acid; Humans; Hypertension; Middle Aged; Nitric Oxide Synthase Type III; Polymorphism, Genetic | 2007 |
The genetic polymorphisms of beta3-adrenergic receptor (AR) Trp64Arg and beta2-AR Gln27Glu are associated with obesity in Chinese male hypertensive patients.
Topics: Aged; Arginine; Base Sequence; DNA Primers; Glutamic Acid; Glycine; Humans; Hypertension; Male; Middle Aged; Obesity; Polymerase Chain Reaction; Polymorphism, Genetic; Receptors, Adrenergic, beta-3; Tryptophan | 2007 |
Chronic nicotine administration. Analysis of the development of hypertension and glutamatergic neurotransmission.
Topics: Analysis of Variance; Animals; Blood Pressure; Brain; Chromatography, High Pressure Liquid; Competitive Bidding; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Excitatory Amino Acid Agonists; Gene Expression Regulation; Glutamic Acid; Hypertension; In Situ Hybridization; Male; Nicotine; Nicotinic Agonists; Protein Binding; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2007 |
Spontaneously hypertensive rats are highly vulnerable to AMPA-induced brain lesions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Brain Damage, Chronic; Brain Ischemia; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Death; Genetic Predisposition to Disease; Glutamic Acid; Hypertension; Ion Channel Gating; Male; Membrane Potentials; Nerve Degeneration; Neurotoxins; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, AMPA; Regional Blood Flow; Vascular Resistance | 2007 |
Association of eNOS Glu298Asp gene polymorphism with essential hypertension in Asian Indians.
Topics: Adult; Alleles; Aspartic Acid; Female; Genotype; Glutamic Acid; Humans; Hypertension; India; Male; Middle Aged; Nitric Oxide Synthase Type III; Polymorphism, Genetic | 2008 |
Sustained hypertension increases the density of AMPA receptor subunit, GluR1, in baroreceptive regions of the nucleus tractus solitarii of the rat.
Topics: Animals; Baroreflex; Dendritic Spines; Down-Regulation; Glutamic Acid; Hydralazine; Hypertension; Male; Microscopy, Immunoelectron; Organ Culture Techniques; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptors, AMPA; Solitary Nucleus; Synaptic Membranes; Synaptic Transmission; Up-Regulation; Vagus Nerve; Vasodilator Agents; Visceral Afferents | 2008 |
Cardiovascular effects of L-glutamate injected in the medial prefrontal cortex of spontaneously hypertensive rats.
Topics: Adrenergic beta-1 Receptor Antagonists; Analysis of Variance; Animals; Atenolol; Blood Pressure; Bradycardia; Cardiovascular Physiological Phenomena; Dose-Response Relationship, Drug; Glutamic Acid; Hypertension; Male; Microinjections; Muscarinic Antagonists; Prefrontal Cortex; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Adrenergic, beta-1; Species Specificity; Time Factors; Tropanes | 2008 |
Pre- and postsynaptic plasticity underlying augmented glutamatergic inputs to hypothalamic presympathetic neurons in spontaneously hypertensive rats.
Topics: Animals; Cells, Cultured; Glutamic Acid; Hypertension; Hypothalamus; Male; Neural Pathways; Neuronal Plasticity; Neurons; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Neurotransmitter; Sympathetic Nervous System; Synaptic Transmission | 2008 |
Destruction of noradrenergic neurons in rabbit brainstem elevates plasma vasopressin, causing hypertension.
Topics: Adrenergic Fibers; Animals; Arginine Vasopressin; Blood Pressure; Brain Stem; Glutamates; Glutamic Acid; Hypertension; Hypothalamus; Kainic Acid; Male; Neurosecretion; Norepinephrine; Rabbits | 1982 |
Glutamatergic mechanisms in the nucleus tractus solitarius in blood pressure control.
Topics: Acetylcholine; Afferent Pathways; Animals; Blood Pressure; Brain; Glutamates; Glutamic Acid; Heart Rate; Hypertension; Male; Medulla Oblongata; Pressoreceptors; Rats; Rats, Inbred Strains; Reflex; Serotonin; Vagus Nerve | 1984 |
The GABA/benzodiazepine receptor complex in the nervous system of a hypertensive strain of rat.
Topics: Aging; Animals; Brain; Cerebellum; Cerebral Cortex; Flunitrazepam; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, GABA-A; Synaptic Membranes | 1984 |
Altered tonic L-3,4-dihydroxyphenylalanine systems in the nucleus tractus solitarii and the rostral ventrolateral medulla of spontaneously hypertensive rats.
Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Biogenic Monoamines; Blood Pressure; Dopamine; Dose-Response Relationship, Drug; Glutamic Acid; Heart Rate; Hypertension; Levodopa; Male; Medulla Oblongata; Microdialysis; Microinjections; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Solitary Nucleus; Tyrosine 3-Monooxygenase | 1995 |
Enhanced sympathetic reactivity to glutamate stimulation in medulla oblongata of spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Brain Mapping; Cerebrovascular Disorders; Electric Stimulation; Glutamic Acid; Hypertension; Kidney; Male; Medulla Oblongata; Neurons; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rest; Sympathetic Nervous System; Vasomotor System | 1995 |
A fall in arterial blood pressure produced by inhibition of the caudalmost ventrolateral medulla: the caudal pressor area.
Topics: Animals; Arteries; Blood Pressure; Carotid Arteries; Constriction; Decerebrate State; Glutamic Acid; Hypertension; Male; Medulla Oblongata; Microinjections; Neural Inhibition; Rats; Rats, Wistar | 1994 |
Cardiovascular effects of microinjection of atrial natriuretic factor (ANF) in the nucleus tractus solitarii of spontaneously hypertensive rats.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Cardiovascular System; Glutamic Acid; Heart Rate; Hypertension; Male; Medulla Oblongata; Microinjections; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1994 |
Enhanced gamma-aminobutyric acid-mediated responses in nucleus tractus solitarius of hypertensive rats.
Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Analysis of Variance; Animals; Blood Pressure; Desoxycorticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; GABA-B Receptor Antagonists; Glutamates; Glutamic Acid; Heart Rate; Hypertension; Male; Neurotransmitter Agents; Nipecotic Acids; Organophosphorus Compounds; Pressoreceptors; Proline; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, GABA-B; Sodium Chloride; Solitary Nucleus; Vigabatrin | 1993 |
Increased dietary salt sensitizes vasomotor neurons of the rostral ventrolateral medulla.
Topics: Analysis of Variance; Animals; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Glutamates; Glutamic Acid; Heart Rate; Hypertension; Male; Medulla Oblongata; Motor Neurons; Neurotransmitter Agents; Norepinephrine; Phenylephrine; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Sympathetic Nervous System | 1993 |
Increased blood-brain barrier permeability of amino acids in chronic hypertension.
Topics: Animals; Blood Pressure; Blood-Brain Barrier; Brain; Cell Membrane Permeability; Cerebellum; Cerebral Cortex; Glutamates; Glutamic Acid; Hypertension; Medulla Oblongata; Organ Specificity; Pons; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Tryptophan | 1993 |
Glutamatergic regulation of [3H]-noradrenaline release in the medulla oblongata of normotensive and spontaneously hypertensive rats.
Topics: Animals; Dizocilpine Maleate; Glutamic Acid; Glycine; Hypertension; Male; Medulla Oblongata; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Reference Values; Tritium | 1994 |
Opposing effects on blood pressure following the activation of metabotropic and ionotropic glutamate receptors in raphe obscurus in the anaesthetized rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Benzoates; Blood Pressure; Cycloleucine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hypertension; Male; Microinjections; N-Methylaspartate; Neurotoxins; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Structure-Activity Relationship; Valine | 1996 |
Altered responsiveness of medullary depressor neurones to L-glutamate and D-serine in SHR rats.
Topics: Animals; Blood Pressure; Glutamic Acid; Hypertension; Kynurenic Acid; Medulla Oblongata; Microinjections; Neurons; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Glycine; Serine; Stereoisomerism | 1996 |
Glutamatergic regulation of [3H]acetylcholine release in striatal slices of normotensive and spontaneously hypertensive rats.
Topics: Acetylcholine; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hypertension; In Vitro Techniques; Male; Neostriatum; Parasympathetic Nervous System; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley | 1996 |
Altered basal release and pressor effect of L-DOPA in the rostral ventrolateral medulla of spontaneously hypertensive rats.
Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Blood Pressure; Dopamine Agents; Glutamic Acid; Heart Rate; Hypertension; Levodopa; Male; Medulla Oblongata; Microdialysis; Microinjections; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrodotoxin; Tyrosine; Tyrosine 3-Monooxygenase | 1995 |
Role of spinal GABA receptors in depressor responses to chemical stimulation of the A5 area in normal and hypertensive rats.
Topics: Animals; Bicuculline; Blood Pressure; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Glutamic Acid; Hemodynamics; Hypertension; Injections, Spinal; Male; Muscimol; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, GABA; Spinal Cord; Stimulation, Chemical | 1997 |
Antihypertensive treatment and the responsiveness to glutamate in ventrolateral medulla.
Topics: Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Body Weight; Enalapril; Excitatory Amino Acid Agonists; Glutamic Acid; Heart Rate; Hypertension; Medulla Oblongata; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Glutamate | 1998 |
Hypotensive effect of gamma-glutamylmethylamide in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hypertension; Male; Rats; Rats, Inbred SHR; Tea | 1998 |
Endothelin-1 facilitates synaptic transmission in the nucleus tractus solitarii in normotensive rats but not in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Electric Stimulation; Endothelin Receptor Antagonists; Endothelin-1; Glutamic Acid; Heart Rate; Hypertension; In Vitro Techniques; Iontophoresis; Male; Microelectrodes; Neurons; Peptides, Cyclic; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Endothelin A; Signal Transduction; Solitary Nucleus; Synaptic Transmission | 1999 |
Identification of a polymorphic glutamic acid stretch in the alpha2B-adrenergic receptor and lack of linkage with essential hypertension.
Topics: Alleles; Blood Pressure; DNA; DNA Primers; Gene Frequency; Genetic Linkage; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Humans; Hypertension; Mutation; Polymorphism, Genetic; Receptors, Adrenergic, alpha-2; Sympathetic Nervous System | 1999 |
Rostral ventrolateral medulla : A source of sympathetic activation in rats subjected to long-term treatment with L-NAME.
Topics: Animals; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hypertension; Kynurenic Acid; Male; Medulla Oblongata; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Sympathetic Nervous System | 1999 |
Excitatory amino acids in the rostral ventrolateral medulla support blood pressure in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Excitatory Amino Acid Antagonists; GABA Agonists; Glutamic Acid; Heart Rate; Hypertension; Kynurenic Acid; Male; Medulla Oblongata; Muscimol; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Glutamate | 2000 |
alpha(2)-adrenergic receptors are not required for central anti-hypertensive action of moxonidine in mice.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Amygdala; Animals; Antihypertensive Agents; Benzofurans; Binding, Competitive; Blood Pressure; Brain Chemistry; Glutamic Acid; Heart Rate; Hypertension; Imidazoles; Imidazoline Receptors; Injections, Intravenous; Medulla Oblongata; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Microinjections; Pons; Receptors, Adrenergic, alpha-2; Receptors, Drug | 2000 |
Cardiovascular responses to glutamate and angiotensin II in ventrolateral medulla of hypertension induced by chronic inhibition of nitric oxide.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiovascular System; Enzyme Inhibitors; Glutamic Acid; Heart Rate; Hypertension; Male; Medulla Oblongata; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Time Factors | 2000 |
Differential cardiorespiratory control elicited by activation of ventral medullary sites in mice.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Benzazepines; Cardiovascular Physiological Phenomena; Catecholamines; Diaphragm; Electric Stimulation; Glutamic Acid; Hemodynamics; Hypertension; Medulla Oblongata; Mice; Mice, Inbred C57BL; Neurons; Receptors, Adrenergic, alpha-2; Respiratory Mechanics; Respiratory Physiological Phenomena; Stereotaxic Techniques; Tyrosine 3-Monooxygenase | 2000 |
Beta(2)-adrenergic receptor gene variation and hypertension in subjects with type 2 diabetes.
Topics: Aged; Analysis of Variance; Arginine; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Genetic Variation; Genotype; Glutamic Acid; Glutamine; Glycine; Humans; Hypertension; Male; Middle Aged; Polymorphism, Genetic; Receptors, Adrenergic, beta-2 | 2001 |
Differential role of kinases in brain stem of hypertensive and normotensive rats.
Topics: Androstadienes; Angiotensin II; Animals; Apnea; Blood Pressure; Brain Stem; Enzyme Inhibitors; Flavonoids; Glutamic Acid; Hypertension; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstrictor Agents; Wortmannin | 2001 |
Association of beta2-adrenoceptor Gln27Glu variant with body weight but not hypertension.
Topics: Body Weight; Case-Control Studies; Chromosomes, Human, Pair 5; Cohort Studies; Genetic Markers; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Glutamine; Humans; Hypertension; Obesity; Receptors, Adrenergic, beta-2; Risk Factors | 2001 |
Endothelial nitric oxide synthase gene Glu298Asp polymorphism and blood pressure, left ventricular mass and carotid artery atherosclerosis in a population-based cohort.
Topics: Alleles; Aspartic Acid; Blood Pressure; Carotid Stenosis; Case-Control Studies; Cohort Studies; Cross-Sectional Studies; Endothelium, Vascular; Female; Finland; Gene Frequency; Genetics, Population; Genotype; Glutamic Acid; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Polymorphism, Genetic; Risk | 2002 |
Involvement of rat lateral septum-acetylcholine pressor system in central amygdaloid nucleus-emotional pressor circuit.
Topics: Acetylcholine; Amygdala; Animals; Atropine; Corticotropin-Releasing Hormone; Glutamic Acid; Habenula; Hypertension; Hypothalamus; Locus Coeruleus; Male; Medulla Oblongata; Muscarinic Antagonists; Rats; Rats, Wistar; Septal Nuclei; Stress, Psychological; Substance P | 2002 |
Multiple panel of biomarkers for TIA/stroke evaluation.
Topics: Adult; Antibodies, Anticardiolipin; Antibodies, Antiphospholipid; Autoantibodies; Biomarkers; Diagnosis, Differential; Disease Progression; Female; Glutamic Acid; Glycine; Homocysteine; Humans; Hypertension; Ischemic Attack, Transient; Magnetic Resonance Imaging; Male; Middle Aged; Myocardial Infarction; Neuroprotective Agents; Predictive Value of Tests; Receptors, N-Methyl-D-Aspartate; Stroke; Tomography, X-Ray Computed | 2002 |
Difference in distribution of glutamate-immunoreactive neurons projecting into the subretrofacial nucleus in the rostral ventrolateral medulla of SHR and WKY: a double-labeling study.
Topics: Animals; Genealogy and Heraldry; Glutamates; Glutamic Acid; Hemodynamics; Horseradish Peroxidase; Hypertension; Immunohistochemistry; Male; Medulla Oblongata; Microelectrodes; Neural Pathways; Neurons; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1992 |
Excitatory and inhibitory amino acid changes in ischemic brain regions in spontaneously hypertensive rats.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Cerebral Cortex; Corpus Striatum; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Hippocampus; Hypertension; Ischemic Attack, Transient; Male; Nucleus Accumbens; Rats; Rats, Inbred SHR; Septum Pellucidum; Taurine | 1991 |
Chemical stimulation of the ventrolateral medullary depressor area decreases ipsilateral cerebral blood flow in anesthetized rats.
Topics: Animals; Blood Pressure; Carbon Dioxide; Cerebral Cortex; Cerebrovascular Circulation; Functional Laterality; Glutamates; Glutamic Acid; Hemorrhage; Hypertension; Hypotension; Male; Medulla Oblongata; Microinjections; Oxygen; Partial Pressure; Rats; Rats, Inbred Strains; Reference Values | 1991 |
Enhanced norepinephrine release in hypothalamus from locus coeruleus in SHR.
Topics: Animals; Blood Pressure; Glutamates; Glutamic Acid; Hydroxydopamines; Hypertension; Hypothalamus; Locus Coeruleus; Microinjections; Norepinephrine; Oxidopamine; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1991 |
Altered cardiovascular responses to glutamate and acetylcholine microinjected into the nucleus tractus solitarii of the SHR.
Topics: Acetylcholine; Animals; Blood Pressure; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Heart Rate; Hypertension; Medulla Oblongata; Microinjections; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1991 |
Glutamate-immunoreactive neurons of the central amygdaloid nucleus projecting to the subretrofacial nucleus of SHR and WKY rats: a double-labeling study.
Topics: Afferent Pathways; Amygdala; Animals; Blood Pressure; Electric Stimulation; Glutamates; Glutamic Acid; Hypertension; Male; Medulla Oblongata; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasomotor System | 1991 |
Cardiovascular effects of L-glutamate and tetrodotoxin microinjected into the rostral and caudal ventrolateral medulla in normotensive and spontaneously hypertensive rats.
Topics: Action Potentials; Animals; Blood Pressure; Glutamates; Glutamic Acid; Heart Rate; Hypertension; Medulla Oblongata; Rats; Rats, Inbred SHR; Tetrodotoxin | 1990 |
The rostral and caudal ventrolateral medulla in young spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Chlorisondamine; Glutamates; Glutamic Acid; Heart Rate; Hypertension; Medulla Oblongata; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Sympathetic Nervous System | 1990 |
Evidence for clonidine presynaptically modulating amino acid release in the rostral ventral medulla: role in hypertension.
Topics: Amino Acids; Animals; Aspartic Acid; Clonidine; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hypertension; In Vitro Techniques; Medulla Oblongata; Neurotransmitter Agents; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Synapses; Synaptic Transmission; Synaptosomes; Yohimbine | 1990 |
A new hemoglobin variant, Hb Mito [beta 144(HC 1) Lys----Glu], with increased oxygen affinity.
Topics: Amino Acid Sequence; Electrophoresis, Cellulose Acetate; Female; Glutamates; Glutamic Acid; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Hypertension; Isoelectric Focusing; Japan; Lysine; Middle Aged; Oxygen | 1985 |
Alterations in responsiveness of noradrenergic neurons of the locus coeruleus in deoxycorticosterone acetate (DOCA)-salt hypertensive rats.
Topics: Animals; Desoxycorticosterone; Epinephrine; Glutamates; Glutamic Acid; Hypertension; Locus Coeruleus; Norepinephrine; Rats; Rats, Inbred Strains; Sodium Chloride; Synaptic Transmission | 1987 |
Acute central effects of L-glutamate in pentobarbital-anesthetized dogs.
Topics: Anesthesia; Animals; Atropine; Blood Pressure; Cardiovascular System; Dogs; Dose-Response Relationship, Drug; Female; Glutamates; Glutamic Acid; Heart Rate; Hexamethonium Compounds; Hypertension; Injections, Intraventricular; Male; Methylene Blue; Pentobarbital; Propranolol | 1987 |
Development of angiotensin II-sensitive OVLT neurons in SHR and WKY rats.
Topics: Action Potentials; Aging; Angiotensin II; Animals; Glutamates; Glutamic Acid; Hypertension; Hypothalamus; In Vitro Techniques; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains | 1988 |
Glutamergic transmission and cardiovascular apparatus in normotensive rats.
Topics: Animals; Blood Pressure; Brain; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Heart Rate; Hypertension; Male; Rats | 1988 |
Role of the nucleus ambiguus in the regulation of heart rate and arterial pressure.
Topics: Animals; Blood Pressure; Bradycardia; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Heart Rate; Hypertension; Kainic Acid; Male; Medulla Oblongata; Rats; Rats, Inbred Strains; Sinoatrial Node | 1988 |