glutamic acid and Bipolar Disorder

glutamic acid has been researched along with Bipolar Disorder in 114 studies

Research

Studies (114)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (1.75)	18.2507
2000's	45 (39.47)	29.6817
2010's	51 (44.74)	24.3611
2020's	16 (14.04)	2.80

Authors

Authors	Studies
Adamson, MM; Hadipour, AL; Kazemi, R; Luttenbacher, I; Martinez, J; Phillips, A; Sanghvi, I	1
Barbini, B; Benedetti, F; Bravi, B; Dallaspezia, S; Melloni, EMT; Poletti, S; Zanardi, R	1
Allauze, E; Chabert, J; Chassain, C; De Chazeron, I; Fossati, P; Llorca, PM; Pereira, B; Rotgé, JY; Samalin, L	1
Guglielmo, R; Hasler, G	1
Cory, B; Fivaz, M; Lim, KL; Tang, W	1
Honda, S; Horita, N; Ino, H; Meyer, JH; Mimura, M; Moriguchi, S; Nakajima, S; Noda, Y; Tsugawa, S; Yamada, K; Yoshida, K	1
Chen, Y; Chen, YF; Dai, A; Fu, CL; Gage, FH; Huang, X; Liu, YN; Lu, SY; Shen, W; Wang, QW; Wang, YH; Wei, H; Xu, Q; Yao, J	1
Brietzke, E; Carmona, NE; Cosgrove, VE; Hajek, T; Iacobucci, M; Kramer, NE; Lee, Y; Mansur, RB; McIntyre, RS; Nasri, F; Newport, J; Pan, Z; Rodrigues, N; Rosenblat, JD; Shekotikhina, M; Subramaniapillai, M; Suppes, T	1
Andrews, T; Benevenuto, D; Lima, CNC; Quevedo, J; Scaini, G; Streck, EL	1
Adler, CM; Blom, TJ; Cecil, KM; DelBello, MP; Nery, FG; Patino, LR; Tallman, MJ	1
Ab Razak, A; Wan Azman, WN; Wan Nasru, WN; Yaacob, NM	1
Henter, ID; Park, LT; Zarate, CA	1
Chen, Y; Lu, SY; Wang, B; Wang, QW; Wang, YH; Yao, J	1
El-Mallakh, RS; Gao, Y; Hu, M	1
Aryutova, K; Kandilarova, S; Paunova, R; Stoyanov, D; Todeva-Radneva, A	1
Arnold, L; Hix, S; Mellick, W; Prisciandaro, JJ; Squeglia, LM; Tolliver, BK	1
Cohen, BM; Coyle, JT; Du, F; Jensen, JE; Kaufman, MJ; Kim, SY; Öngür, D	1
Galińska-Skok, B; Gierus, J; Marcinowicz, P; Mosiolek, A; Szulc, A; Waszkiewicz, N; Wiedlocha, M	1
Algın, O; Atagün, Mİ; Can, SS; Çayköylü, A; Kaymak, SU; Moore, CM; Öngür, D; Phillips, ML; Şıkoğlu, EM; Uğurlu, GK	1
Lafer, B; Leite, C; Machado-Vieira, R; Moreno, RA; Nery, FG; Otaduy, MCG; Soeiro-de-Souza, MG	1
Guadagno, E; Li, C; Ramamurthy, J; Trakadis, Y; Wang, A; Wang, C; Zhang, E	1
Horne, CM; Jelen, LA; King, S; Lythgoe, DJ; Stone, JM; Young, AH	1
Bargiotas, T; Cowen, PJ; Emir, UE; Godlewska, BR; Masaki, C	1
Balakrishnan, A; Bhat, M; Joshi, MB; Kotambail, A; Pai, S; Satyamoorthy, K; Sharma, P	1
Chitty, KM; Duffy, SL; Hermens, DF; Hickie, IB; Kaur, M; Lagopoulos, J	1
Chavez, S; Kolla, NJ; Lobaugh, NJ; Meyer, JH; Smaragdi, A	1
Forester, BP; Harper, DG; Jensen, E; Mellen, EJ; Ravichandran, C; Silveri, M	1
Backlund, L; Biernacka, JM; Bond, DJ; Choi, DS; Frye, MA; Geske, JR; Ho, AM; Jia, YF; Lavebratt, C; McElroy, SL; Millischer, V; Port, JD; Schalling, M; Skime, M; Veldic, M; Villaescusa, JC	1
Anand, A; Dydak, U; Dzemidzic, M; Gunn, AD; Harezlak, J; Karne, HS; Nixon, J; Xu, J	1
Cowen, PJ; Godlewska, BR; Goodwin, GM; Near, J; Yip, SW	1
Chitty, KM; Hermens, DF; Hickie, IB; Lagopoulos, J; Lee, RS	1
Gigante, AD; Lafer, B; Yatham, LN	1
Kuswanto, CN; Low, CM; Nowinski, WL; Sim, K; Sitoh, YY; Sum, MY; Thng, CR; Yang, GL; Zhang, YB	1
Buonaguro, EF; de Bartolomeis, A; Iasevoli, F; Tomasetti, C	1
Cohen, BM; Duncan, LE; Holmans, PA; Kirby, AW; Lee, PH; O'Dushlaine, CT; Öngür, D; Smoller, JW	1
Taylor, MJ	1
Ågren, H; Ekman, CJ; Fujita, Y; Hashimoto, K; Jakobsson, J; Landén, M; Pålsson, E; Sellgren, C; Södersten, K	1
Busatto, GF; de Sousa, RT; Gattaz, WF; Leite, CC; Machado-Vieira, R; Otaduy, MC; Zanetti, MV	1
Ehrlich, A; Gallinat, J; Pehrs, C; Schubert, F	1
Chitty, KM; Hermens, DF; Hickie, IB; Lagopoulos, J	1
Castro, MC; Czerniak, SM; Dvir, Y; Edden, RA; Frazier, JA; Moore, CM; Navarro, AA; Nwosu, BU; Rogan, RC; Sikoglu, EM; Starr, D	1
Arias, B; Benabarre, A; Bobes, J; Burón, P; García-Portilla, MP; Goikolea, JM; Jiménez, E; Mitjans, M; Sáiz, PA; Vieta, E	1
Allyn-Feuer, A; Athey, BD; Barbour, E; Higgins, GA	1
Carvalho, AF; De Sousa, RT; Gattaz, WF; Leite, CC; Machado-Vieira, R; Otaduy, MC; Soeiro-de-Souza, MG; Zanetti, MV	1
da Costa Leite, C; Henning, A; Machado-Vieira, R; Moreno, RA; Otaduy, MC; Pastorello, BF; Soeiro-de-Souza, MG; Vallada, H	1
Dalvie, S; Fabbri, C; Ramesar, R; Serretti, A; Stein, DJ	1
Bond, DJ; da Silveira, LE; Honer, WG; Lam, RW; Lang, DJ; MacMillan, EL; Su, W; Torres, IJ; Yatham, LN	1
El-Mallakh, RS; Gao, Y; Lei, Z; Roisen, F; Schroeder, E	1
Bond, DJ; Bücker, J; Kapczinski, F; Kozicky, JM; MacMillan, EL; Muralidharan, K; Rosa, AR; Silveira, LE; Yatham, LN	1
Bao, AM; Wu, JL; Wu, SH; Yu, SY	1
Cao, B; Mwangi, B; Passos, IC; Selvaraj, S; Soares, JC; Stanley, JA; Zunta-Soares, GB	1
Breen, ME; de Klerk, K; DeLuca, AP; Gaynor, SC; Monson, ET; Parsons, M; Potash, JB; Scheetz, TE; Willour, VL; Zandi, PP	1
Funakoshi, Y; Harada, M; Iga, JI; Inoshita, M; Kameoka, N; Kinoshita, M; Kubo, H; Nakataki, M; Nakayama-Yamauchi, C; Numata, S; Ohmori, T; Ohta, M; Sumitani, S; Tamaru, M; Umehara, H; Watanabe, SY	1
Cohen, BM; Jensen, JE; Lundy, M; Öngür, D; Prescot, AP; Renshaw, PF; Stork, C	1
Sümegi, A	2
Alda, M; Calkin, C; Hajek, T; O'Donovan, C	1
Graham, S; Lau, IY; Ng, WX; Sim, K	1
Benzel, I; de Belleroche, J; Hirsch, S; Kelly, F; Kew, JN; Maycox, PR; Sanderson, TH; Viknaraja, R	1
Adler, CM; Cecil, KM; DelBello, MP; Patel, NC; Strakowski, SM	1
Jensen, JE; Kaufman, RE; Marks, EH; Ostacher, MJ; Pollack, MH; Renshaw, PF; Sachs, GS; Simon, NM	1
Cohen, BM; Haws, C; Kim, TS; Lyoo, IK; Renshaw, PF; Yoon, SJ	1
Erfurth, A; Michael, N; Pfleiderer, B	1
Renshaw, PF	1
Hall, GB; MacQueen, GM; Milne, AM; Senaratne, R	1
Benedetti, F; Bernasconi, A; Cadioli, M; Calabrese, G; Colombo, C; Dallaspezia, S; Falini, A; Radaelli, D; Scotti, G; Smeraldi, E	1
Mill, J; Rutten, BP	1
Brennan, BP; Cohen, BM; Hudson, JI; Jensen, JE; McCarthy, J; Ongür, D; Pope, HG; Prescot, AP; Renshaw, PF; Roberts, JL	1
Cherlyn, SY; Liu, JJ; Ong, WY; Sim, K; Tsai, GC; Woon, PS	1
Eastwood, SL; Harrison, PJ	1
Adleman, N; Alegria, D; Chang, K; Howe, M; Reiss, A; Singh, M; Spielman, D	1
Chen, G; Henter, ID; Manji, HK	1
Agam, G; Ben-Shachar, D	1
Backens, M; Ekawardhani, S; Falkai, P; Gruber, O; Hasan, A; Meyer, J; Reith, W; Scherk, H; Schmitt, A; Schneider-Axmann, T; Wobrock, T	1
Anand, A; Barkay, G; Ghosh, S; Gunn, AD; Karne, HS; Mathew, SJ; Nurnberger, JI	1
Bao, AM; Kamphuis, W; Lou, JS; Luchetti, S; Qi, XR; Swaab, DF; Zhao, J	1
Rezaei, Z; Saadat, I; Saadat, M	1
Abelli, M; Cardini, A; Cassano, GB; Da Pozzo, E; Daniele, S; Gesi, C; Lari, L; Martini, C; Panighini, A; Pini, S	1
Adler, CM; Alfieri, DC; Blom, TJ; Bryan, HS; Chu, WJ; DelBello, MP; Kim, MJ; Lee, JH; Nandagopal, JJ; Patel, NC; Strakowski, SM; Strawn, JR; Welge, JA	1
Bond, DJ; Gigante, AD; Lafer, B; Lam, RW; Yatham, LN; Young, LT	1
Chaim, KT; Gattaz, WF; Machado-Vieira, R; Moreno, RA; Otaduy, MC; Salvadore, G; Soeiro-de-Souza, MG; Zarate, CA	1
Magistretti, P; Pralong, E; Stoop, R	1
Arolt, V; Erfurth, A; Gössling, M; Heindel, W; Michael, N; Ohrmann, P; Pfleiderer, B	1
Braff, DL; Kelsoe, JR; Schuckit, MA; Wilhelmsen, KC	1
Alda, M; Bauer, M; Priller, J; Young, LT	1
Amore, M; Canaider, S; Carinci, P; Casadei, R; D'Addabbo, P; Ferrari, G; Frabetti, F; Laterza, C; Lenzi, L; Strippoli, P; Tagariello, P; Torroni, A; Vitale, L; Zannotti, M	1
Dager, SR; Demopulos, C; Dunner, DL; Friedman, SD; Hirashima, F; Lyoo, IK; Parow, A; Renshaw, PF; Stoll, AL	1
Fekkes, D; Hoekstra, R; Loonen, AJ; Pepplinkhuizen, L; Tuinier, S; Verhoeven, WM	1
Akil, H; Bunney, WE; Choudary, PV; Evans, SJ; Jones, EG; Li, JZ; Molnar, M; Myers, RM; Tomita, H; Vawter, MP; Watson, SJ	1
Kugaya, A; Sanacora, G	1
Chopra, V; Flibotte, S; Holt, RA; Honer, WG; Melnyk, BL; Wilson, GM	1
Aleardi, M; Biederman, J; Dougherty, M; Hammerness, P; Harpold, T; Mick, E; Moore, CM; Randall, E; Renshaw, PF; Wardrop, M; Wozniak, J	1
Borges, VC; do Nascimento, CA; Nogueira, CW; Rocha, JB	1
Ankerst, DP; Yildiz-Yesiloglu, A	1
Coyle, JT; Frye, MA; Huggins, T; Post, RM; Tsai, GE	1
Chang, K; Howe, M; Saxena, K; Simeonova, D; Steiner, H	1
Bortolato, M; Casti, A; Fà, M; Fais, N; Frau, R; Gessa, G; Manunta, M; Mereu, G; Orrù, M	1
Aleardi, M; Biederman, J; Dougherty, M; Hammerness, P; Harpold, T; Lyoo, IK; Mick, E; Moore, CM; Randall, E; Renshaw, PF; Wardrop, M; Wozniak, J	1
Beneyto, M; Dean, B; Kristiansen, LV; McCullumsmith, RE; Meador-Woodruff, JH; Scarr, E	1
Ashworth, F; Bhagwagar, Z; Cowen, PJ; Evans, J; Jezzard, P; Matthews, PM; Sule, A; Wylezinska, M	1
Breeze, JL; Dieterich, M; Finn, CT; Frazier, JA; Frederick, Bd; Glod, CA; Moore, CM; Renshaw, PF	1
Banakar, S; Chirichigno, JW; Davanzo, P; Elman, S; Fischer, J; Frye, MA; Mintz, J; O'Neill, J; Thomas, MA; Tsuang, J; Ventura, J; Walot, I; Watzl, J	1
Bennett, MR	1
Andreazza, AC; Frey, BN; Kapczinski, F; Martins, MR; Nery, FG; Quevedo, J; Soares, JC	1
Marcus, SM; Mrazek, DA; Port, JD; Unal, SS	1
Bahn, S; Griffin, JL; Holmes, E; Huang, JT; Lan, MJ; Manji, H; McLoughlin, GA; Tsang, TM; Yuan, P	1
Bajbouj, M; Bubner, M; Colla, M; Heidenreich, JO; Heuser, I; Kronenberg, G; Luborzewski, A; Schubert, F; Seifert, F	1
Kloos, A; Weller, EB; Weller, RA	1
Dixon, JF; Hokin, LE	2
Castillo, M; Courvoisie, H; Hooper, SR; Kwock, L	1
Deakin, JF; Law, AJ	1
Chalecka-Franaszek, E; Chen, RW; Chuang, DM; Hashimoto, R; Hiroi, T; Hough, C; Kanai, H; Leeds, P; Ren, M; Senatorov, V	1
Frye, MA; Ketter, TA; Li, X	1

Reviews

28 review(s) available for glutamic acid and Bipolar Disorder

Article	Year
Transdiagnostic role of glutamate and white matter damage in neuropsychiatric disorders: A Systematic Review. Journal of psychiatric research, 2022, Volume: 147 Topics: Anisotropy; Bipolar Disorder; Brain; Depressive Disorder, Major; Diffusion Tensor Imaging; Glutamic Acid; Humans; White Matter	2022
Glutamatergic and N-Acetylaspartate Metabolites in Bipolar Disorder: A Systematic Review and Meta-Analysis of Proton Magnetic Resonance Spectroscopy Studies. International journal of molecular sciences, 2022, Aug-11, Volume: 23, Issue:16 Topics: Aspartic Acid; Bipolar Disorder; Depressive Disorder, Major; Glutamic Acid; Glutamine; Humans; Proton Magnetic Resonance Spectroscopy	2022
The neuroprotective and neuroplastic potential of glutamatergic therapeutic drugs in bipolar disorder. Neuroscience and biobehavioral reviews, 2022, Volume: 142 Topics: Animals; Antimanic Agents; Bipolar Disorder; Genome-Wide Association Study; Glutamic Acid; Neuronal Plasticity	2022
Glutamatergic Neurometabolite Levels in Bipolar Disorder: A Systematic Review and Meta-analysis of Proton Magnetic Resonance Spectroscopy Studies. Biological psychiatry. Cognitive neuroscience and neuroimaging, 2023, Volume: 8, Issue:2 Topics: Adult; Bipolar Disorder; Child; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Proton Magnetic Resonance Spectroscopy	2023
Mitochondrial dysfunction as a critical event in the pathophysiology of bipolar disorder. Mitochondrion, 2021, Volume: 57 Topics: Apoptosis; Bipolar Disorder; Brain; Calcium; Gene Expression Regulation; Glutamic Acid; Humans; Mitochondria; Oxidative Stress	2021
Novel Glutamatergic Modulators for the Treatment of Mood Disorders: Current Status. CNS drugs, 2021, Volume: 35, Issue:5 Topics: Animals; Antidepressive Agents; Bipolar Disorder; Depressive Disorder, Major; Excitatory Amino Acid Agents; Glutamic Acid; Humans; Mood Disorders; Receptors, Glutamate	2021
The Translational Potential of Non-coding RNAs and Multimodal MRI Data Sets as Diagnostic and Differential Diagnostic Biomarkers for Mood Disorders. Current topics in medicinal chemistry, 2021, Volume: 21, Issue:11 Topics: Biomarkers; Bipolar Disorder; Brain; Depressive Disorder, Major; Gene Expression Regulation; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; MicroRNAs; Mood Disorders; RNA, Untranslated	2021
Proton magnetic resonance spectroscopy changes after lithium treatment. Systematic review. Psychiatry research. Neuroimaging, 2018, 03-30, Volume: 273 Topics: Antimanic Agents; Aspartic Acid; Bipolar Disorder; Brain; Choline; Cross-Sectional Studies; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inositol; Lithium Compounds; Proton Magnetic Resonance Spectroscopy; Treatment Outcome	2018
Metabolomics in patients with psychosis: A systematic review. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2018, Volume: 177, Issue:6 Topics: 3-Hydroxybutyric Acid; Aspartic Acid; Biomarkers; Bipolar Disorder; Creatine; Female; Glutamic Acid; Glutathione; Humans; Kynurenine; Lactic Acid; Linoleic Acid; Male; Metabolome; Metabolomics; Psychotic Disorders; Schizophrenia; Serine; Tryptophan	2018
A systematic review and meta-analysis of proton magnetic resonance spectroscopy and mismatch negativity in bipolar disorder. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2013, Volume: 23, Issue:11 Topics: Bipolar Disorder; Evoked Potentials; Frontal Lobe; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Protons	2013
The emerging role of dopamine-glutamate interaction and of the postsynaptic density in bipolar disorder pathophysiology: Implications for treatment. Journal of psychopharmacology (Oxford, England), 2014, Volume: 28, Issue:6 Topics: Affect; Antipsychotic Agents; Bipolar Disorder; Brain; Dopamine; Dopaminergic Neurons; Glutamic Acid; Humans; Neuronal Plasticity; Post-Synaptic Density; Synaptic Transmission	2014
Could glutamate spectroscopy differentiate bipolar depression from unipolar? Journal of affective disorders, 2014, Volume: 167 Topics: Adult; Bipolar Disorder; Depressive Disorder, Major; Diagnosis, Differential; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Predictive Value of Tests; Sensitivity and Specificity	2014
[Mood stabilizers--past, present and future]. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2008, Volume: 10, Issue:1 Topics: Affect; Antimanic Agents; Bipolar Disorder; Calcium; Carbamazepine; Depressive Disorder; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Lamotrigine; Lithium Compounds; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Mood Disorders; Triazines; Valproic Acid	2008
Treatment of bipolar disorder: new perspectives. Annals of medicine, 2009, Volume: 41, Issue:3 Topics: Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Glutamic Acid; Glycogen Synthase Kinases; Humans; Lithium Carbonate; Polymorphism, Genetic; Protein Kinase C; Protein Kinase Inhibitors; Synaptic Transmission	2009
Neurobiological evidence for thalamic, hippocampal and related glutamatergic abnormalities in bipolar disorder: a review and synthesis. Neuroscience and biobehavioral reviews, 2009, Volume: 33, Issue:3 Topics: Basal Ganglia; Bipolar Disorder; Glutamic Acid; Hippocampus; Humans; Magnetic Resonance Imaging; Neural Pathways; Neurons; Organ Size; Prefrontal Cortex; Synaptic Transmission; Temporal Lobe; Thalamus	2009
Applications for magnetic resonance imaging in bipolar disorder. CNS spectrums, 2007, Volume: 12, Issue:6 Suppl 8 Topics: Antipsychotic Agents; Aspartic Acid; Bipolar Disorder; Brain; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy	2007
[Quetiapin in bipolar disorders]. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2008, Volume: 10, Issue:5 Topics: Adult; Aged; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Dibenzothiazepines; Dopamine; Female; Glutamic Acid; Humans; Male; Middle Aged; Norepinephrine; Quetiapine Fumarate; Receptors, Histamine; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists	2008
Epigenetic mediation of environmental influences in major psychotic disorders. Schizophrenia bulletin, 2009, Volume: 35, Issue:6 Topics: Alleles; Bipolar Disorder; Child; Child Abuse; Diseases in Twins; DNA Methylation; Epigenesis, Genetic; Female; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamic Acid; Humans; Illicit Drugs; Parenting; Phenotype; Polymorphism, Genetic; Pregnancy; Prenatal Exposure Delayed Effects; Psychoses, Substance-Induced; Risk Factors; Schizophrenia; Schizophrenic Psychology; Social Environment	2009
Genetic association studies of glutamate, GABA and related genes in schizophrenia and bipolar disorder: a decade of advance. Neuroscience and biobehavioral reviews, 2010, Volume: 34, Issue:6 Topics: Animals; Bipolar Disorder; gamma-Aminobutyric Acid; Genetic Association Studies; Glutamic Acid; Humans; Schizophrenia; Synaptic Transmission	2010
Brain glutamate levels measured by magnetic resonance spectroscopy in patients with bipolar disorder: a meta-analysis. Bipolar disorders, 2012, Volume: 14, Issue:5 Topics: Adolescent; Adult; Bipolar Disorder; Brain; Child; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy	2012
Cellular perspectives on the glutamate-monoamine interactions in limbic lobe structures and their relevance for some psychiatric disorders. Progress in neurobiology, 2002, Volume: 67, Issue:3 Topics: Bipolar Disorder; Brain; Depressive Disorder; Dopamine; Glutamic Acid; Humans; Limbic System; Neurotransmitter Agents; Norepinephrine; Receptors, Dopamine; Receptors, Serotonin; Schizophrenia; Serotonin	2002
Implications of the neuroprotective effects of lithium for the treatment of bipolar and neurodegenerative disorders. Pharmacopsychiatry, 2003, Volume: 36 Suppl 3 Topics: Alzheimer Disease; Bipolar Disorder; Glucocorticoids; Glutamic Acid; Humans; Huntington Disease; Lithium Compounds; Nerve Degeneration; Neurodegenerative Diseases; Neuroprotective Agents; Signal Transduction	2003
Beyond monoamines: glutamatergic function in mood disorders. CNS spectrums, 2005, Volume: 10, Issue:10 Topics: Bipolar Disorder; Brain; Clinical Trials as Topic; Depressive Disorder, Major; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Lamotrigine; Magnetic Resonance Spectroscopy; Neuroglia; Receptors, Glutamate; Riluzole; Treatment Outcome; Triazines	2005
Neurochemical alterations of the brain in bipolar disorder and their implications for pathophysiology: a systematic review of the in vivo proton magnetic resonance spectroscopy findings. Progress in neuro-psychopharmacology & biological psychiatry, 2006, Aug-30, Volume: 30, Issue:6 Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain Chemistry; Child; Choline; Creatine; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy	2006
The role of hippocampus in the pathophysiology of bipolar disorder. Behavioural pharmacology, 2007, Volume: 18, Issue:5-6 Topics: Animals; Antimanic Agents; Bipolar Disorder; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Neuronal Plasticity; Radionuclide Imaging	2007
Biologic basis of bipolar disorder in children and adolescents. Current psychiatry reports, 2008, Volume: 10, Issue:2 Topics: Adolescent; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Brain; Brain-Derived Neurotrophic Factor; Child; Energy Metabolism; Genetic Predisposition to Disease; Glutamic Acid; Glutamine; Humans; Lithium Compounds; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Neuropsychological Tests	2008
Neuroprotective effects of lithium in cultured cells and animal models of diseases. Bipolar disorders, 2002, Volume: 4, Issue:2 Topics: Animals; Bipolar Disorder; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Glutamic Acid; Lithium Carbonate; Neurons; Receptors, N-Methyl-D-Aspartate; Stroke	2002
Synaptic, intracellular, and neuroprotective mechanisms of anticonvulsants: are they relevant for the treatment and course of bipolar disorders? Journal of affective disorders, 2002, Volume: 69, Issue:1-3 Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamic Acid; Humans; Lithium; Signal Transduction; Synaptic Transmission; Valproic Acid	2002

Trials

10 trial(s) available for glutamic acid and Bipolar Disorder

Article	Year
Effects of infliximab on brain neurochemistry of adults with bipolar depression. Journal of affective disorders, 2021, 02-15, Volume: 281 Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain; Glutamic Acid; Humans; Infliximab; Neurochemistry; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy	2021
N-acetylcysteine for depression and glutamate changes in the left prefrontal cortex in adolescents and young adults at risk for bipolar disorder: A pilot study. Early intervention in psychiatry, 2022, Volume: 16, Issue:2 Topics: Acetylcysteine; Adolescent; Bipolar Disorder; Depression; Glutamic Acid; Humans; Pilot Projects; Prefrontal Cortex; Young Adult	2022
Results from a randomized, double-blind, placebo-controlled, crossover, multimodal-MRI pilot study of gabapentin for co-occurring bipolar and cannabis use disorders. Addiction biology, 2022, Volume: 27, Issue:1 Topics: Adolescent; Adult; Bipolar Disorder; Cigarette Smoking; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Male; Marijuana Abuse; Middle Aged; Pilot Projects; Proton Magnetic Resonance Spectroscopy; Young Adult	2022
Bimodal effect of lithium plasma levels on hippocampal glutamate concentrations in bipolar II depression: a pilot study. The international journal of neuropsychopharmacology, 2014, Oct-31, Volume: 18, Issue:6 Topics: Adolescent; Adult; Affect; Antimanic Agents; Bipolar Disorder; Brazil; Drug Monitoring; Female; Glutamic Acid; Hippocampus; Humans; Lithium Compounds; Male; Pilot Projects; Proton Magnetic Resonance Spectroscopy; Time Factors; Treatment Outcome; Young Adult	2014
1H-magnetic resonance spectroscopy study of glutamate-related abnormality in bipolar disorder. Journal of affective disorders, 2017, Jan-15, Volume: 208 Topics: Adult; Basal Ganglia; Biomarkers; Bipolar Disorder; Case-Control Studies; Cross-Sectional Studies; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged	2017
Decreased glutamate/glutamine levels may mediate cytidine's efficacy in treating bipolar depression: a longitudinal proton magnetic resonance spectroscopy study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:7 Topics: Administration, Oral; Adult; Antidepressive Agents; Bipolar Disorder; Brain; Chi-Square Distribution; Cytidine; Double-Blind Method; Glutamic Acid; Glutamine; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Middle Aged; Protons; Psychiatric Status Rating Scales; Time Factors; Treatment Outcome; Young Adult	2009
Spectroscopic correlates of antidepressant response to sleep deprivation and light therapy: a 3.0 Tesla study of bipolar depression. Psychiatry research, 2009, Sep-30, Volume: 173, Issue:3 Topics: Adult; Antidepressive Agents; Bipolar Disorder; Brain; Creatine; Female; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phototherapy; Protons; Sleep Deprivation	2009
Early antidepressant effect of memantine during augmentation of lamotrigine inadequate response in bipolar depression: a double-blind, randomized, placebo-controlled trial. Bipolar disorders, 2012, Volume: 14, Issue:1 Topics: Adult; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Depression; Dopamine Agents; Double-Blind Method; Drug Therapy, Combination; Female; Glutamic Acid; Humans; Lamotrigine; Male; Memantine; Middle Aged; Pilot Projects; Treatment Outcome; Triazines	2012
Lithium and valproic acid treatment effects on brain chemistry in bipolar disorder. Biological psychiatry, 2004, Sep-01, Volume: 56, Issue:5 Topics: Adult; Analysis of Variance; Antimanic Agents; Bipolar Disorder; Brain; Brain Chemistry; Brain Mapping; Case-Control Studies; Echo-Planar Imaging; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Lactic Acid; Lithium; Magnetic Resonance Spectroscopy; Male; Psychiatric Status Rating Scales; Valproic Acid	2004
Divalproex sodium reduces overall aggression in youth at high risk for bipolar disorder. Journal of child and adolescent psychopharmacology, 2006, Volume: 16, Issue:3 Topics: Adolescent; Affect; Aggression; Antimanic Agents; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Child; Cyclothymic Disorder; Depressive Disorder, Major; Dysthymic Disorder; Female; GABA Agents; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Risk Factors; Valproic Acid	2006

Other Studies

76 other study(ies) available for glutamic acid and Bipolar Disorder

Article	Year
Antidepressant chronotherapeutics normalizes prefrontal Progress in neuro-psychopharmacology & biological psychiatry, 2022, 12-20, Volume: 119 Topics: Antidepressive Agents; Bipolar Disorder; Depressive Disorder, Major; Drug Chronotherapy; Glutamic Acid; Glutamine; Humans; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy	2022
The Mood Stabilizer Lithium Slows Down Synaptic Vesicle Cycling at Glutamatergic Synapses. Neuromolecular medicine, 2023, Volume: 25, Issue:1 Topics: Action Potentials; Animals; Bipolar Disorder; Cells, Cultured; Endocytosis; Exocytosis; Glutamic Acid; Hippocampus; Lithium Compounds; Presynaptic Terminals; Rats; Synapses; Synaptic Transmission; Synaptic Vesicles	2023
Synaptotagmin-7 deficiency induces mania-like behavioral abnormalities through attenuating GluN2B activity. Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49 Topics: Adult; Aged; Animals; Behavior, Animal; Bipolar Disorder; Exocytosis; Female; Glutamic Acid; Hippocampus; Humans; Induced Pluripotent Stem Cells; Male; Mania; Mice, Knockout; Middle Aged; Neurons; Receptors, N-Methyl-D-Aspartate; Synaptic Vesicles; Synaptotagmins; Young Adult	2020
Alteration of plasma alanine, glutamate, and glycine Level: A potentiate manic episode of bipolar disorder. The Malaysian journal of pathology, 2021, Volume: 43, Issue:1 Topics: Adult; Alanine; Bipolar Disorder; Glutamic Acid; Glycine; Humans; Mania	2021
Synaptotagmin-7-mediated activation of spontaneous NMDAR currents is disrupted in bipolar disorder susceptibility variants. PLoS biology, 2021, Volume: 19, Issue:7 Topics: Animals; Bipolar Disorder; Calcium; Clustered Regularly Interspaced Short Palindromic Repeats; Disease Models, Animal; Genetic Predisposition to Disease; Glutamic Acid; HEK293 Cells; Hippocampus; Humans; Mice; Mice, Knockout; Neurons; Receptors, N-Methyl-D-Aspartate; Synaptotagmins	2021
Neuronal cells from bipolar individuals are more susceptible to glutamate induced apoptosis than cells from non-bipolar subjects. Journal of affective disorders, 2021, 11-01, Volume: 294 Topics: Antimanic Agents; Apoptosis; Bipolar Disorder; Glutamic Acid; Humans; Neurons	2021
In Vivo Brain Glycine and Glutamate Concentrations in Patients With First-Episode Psychosis Measured by Echo Time-Averaged Proton Magnetic Resonance Spectroscopy at 4T. Biological psychiatry, 2018, 03-15, Volume: 83, Issue:6 Topics: Adult; Bipolar Disorder; Brain; Case-Control Studies; Female; Glutamic Acid; Glycine; Humans; Image Processing, Computer-Assisted; Male; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Young Adult	2018
Neurochemical differences between bipolar disorder type I and II in superior temporal cortices: A proton magnetic resonance spectroscopy study. Journal of affective disorders, 2018, 08-01, Volume: 235 Topics: Adult; Bipolar Disorder; Creatine; Cross-Sectional Studies; Cyclothymic Disorder; Female; Glutamic Acid; Humans; Magnetic Resonance Imaging; Male; Phosphocreatine; Proton Magnetic Resonance Spectroscopy; Temporal Lobe; Young Adult	2018
Anterior Cingulate Cortex Glutamatergic Metabolites and Mood Stabilizers in Euthymic Bipolar I Disorder Patients: A Proton Magnetic Resonance Spectroscopy Study. Biological psychiatry. Cognitive neuroscience and neuroimaging, 2018, Volume: 3, Issue:12 Topics: Adolescent; Adult; Affect; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Brain; Cyclothymic Disorder; Female; Glutamic Acid; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Young Adult	2018
Functional magnetic resonance spectroscopy in patients with schizophrenia and bipolar affective disorder: Glutamate dynamics in the anterior cingulate cortex during a working memory task. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2019, Volume: 29, Issue:2 Topics: Adult; Analysis of Variance; Bipolar Disorder; Creatine; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Memory, Short-Term; Middle Aged; Schizophrenia; Young Adult	2019
Changes in brain Glx in depressed bipolar patients treated with lamotrigine: A proton MRS study. Journal of affective disorders, 2019, 03-01, Volume: 246 Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Brain; Female; Glutamic Acid; Humans; Lamotrigine; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Treatment Outcome; Young Adult	2019
Evidence for perturbed metabolic patterns in bipolar disorder subjects associated with lithium responsiveness. Psychiatry research, 2019, Volume: 273 Topics: Adult; Amino Acids, Branched-Chain; Bipolar Disorder; Dopamine; Female; Glutamic Acid; Homeostasis; Humans; Lithium Compounds; Male; Metabolome; Middle Aged; Phenylalanine; Psychotropic Drugs; Treatment Outcome; Tyrosine	2019
Elucidating the glutamatergic processes underlying mismatch negativity deficits in early stage bipolar disorder and schizophrenia: A combined Journal of psychiatric research, 2019, Volume: 113 Topics: Adolescent; Adult; Bipolar Disorder; Electroencephalography; Evoked Potentials, Auditory; Female; Glutamic Acid; Humans; Male; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Young Adult	2019
Differential levels of prefrontal cortex glutamate+glutamine in adults with antisocial personality disorder and bipolar disorder: A proton magnetic resonance spectroscopy study. Progress in neuro-psychopharmacology & biological psychiatry, 2019, 07-13, Volume: 93 Topics: Adult; Antisocial Personality Disorder; Bipolar Disorder; Brain; Case-Control Studies; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Male; Neuroimaging; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy	2019
Lamotrigine Therapy and Biomarkers of Cerebral Energy Metabolism in Older Age Bipolar Depression. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2019, Volume: 27, Issue:8 Topics: Aged; Aging; Antipsychotic Agents; Aspartic Acid; Biomarkers; Bipolar Disorder; Cerebral Cortex; Creatine; Depression; Energy Metabolism; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Humans; Lamotrigine; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Severity of Illness Index; Treatment Outcome	2019
Genetic variant in SLC1A2 is associated with elevated anterior cingulate cortex glutamate and lifetime history of rapid cycling. Translational psychiatry, 2019, 05-23, Volume: 9, Issue:1 Topics: Adult; Bipolar Disorder; Cohort Studies; Depressive Disorder, Major; Excitatory Amino Acid Transporter 2; Female; Glutamic Acid; Gyrus Cinguli; Humans; Hyaluronan Receptors; Male; Middle Aged; Polymorphism, Single Nucleotide; Proton Magnetic Resonance Spectroscopy	2019
Neurochemical abnormalities in unmedicated bipolar depression and mania: a 2D 1H MRS investigation. Psychiatry research, 2013, Sep-30, Volume: 213, Issue:3 Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain; Creatine; Female; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Psychiatric Status Rating Scales; Tritium; Young Adult	2013
Cortical glutathione levels in young people with bipolar disorder: a pilot study using magnetic resonance spectroscopy. Psychopharmacology, 2014, Volume: 231, Issue:2 Topics: Aspartic Acid; Biomarkers; Bipolar Disorder; Case-Control Studies; Female; Functional Neuroimaging; gamma-Aminobutyric Acid; Glutamic Acid; Glutathione; Humans; Magnetic Resonance Spectroscopy; Male; Occipital Lobe; Pilot Projects; Prefrontal Cortex; Young Adult	2014
(1)H-MRS of hippocampus in patients after first manic episode. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2014, Volume: 15, Issue:2 Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Glutamic Acid; Glutamine; Hippocampus; Humans; Hydrogen; Inositol; Magnetic Resonance Spectroscopy; Male; Neurons; Prospective Studies; Time Factors; Young Adult	2014
GRIN2B gene and associated brain cortical white matter changes in bipolar disorder: a preliminary combined platform investigation. BioMed research international, 2013, Volume: 2013 Topics: Adult; Aged; Bipolar Disorder; Brain; Female; Genotype; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Leukoencephalopathies; Male; Middle Aged; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synaptic Transmission	2013
Pathway analyses implicate glial cells in schizophrenia. PloS one, 2014, Volume: 9, Issue:2 Topics: Bipolar Disorder; Case-Control Studies; Genetic Predisposition to Disease; Genome-Wide Association Study; Glutamic Acid; Humans; Mitochondria; Neuroglia; Polymorphism, Single Nucleotide; Schizophrenia; Signal Transduction	2014
Markers of glutamate signaling in cerebrospinal fluid and serum from patients with bipolar disorder and healthy controls. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2015, Volume: 25, Issue:1 Topics: Adult; Bipolar Disorder; Female; Glutamic Acid; Glutamine; Glycine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Serine	2015
Alterations of cerebral glutamate in the euthymic state of patients with bipolar disorder. Psychiatry research, 2015, Aug-30, Volume: 233, Issue:2 Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Female; Glutamic Acid; Gyrus Cinguli; Hippocampus; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy	2015
Hippocampal glutamatergic/NMDA receptor functioning in bipolar disorder: A study combining mismatch negativity and proton magnetic resonance spectroscopy. Psychiatry research, 2015, Aug-30, Volume: 233, Issue:2 Topics: Adult; Bipolar Disorder; Creatine; Electroencephalography; Evoked Potentials; Female; Glutamic Acid; Hippocampus; Humans; Male; Proton Magnetic Resonance Spectroscopy; Receptors, N-Methyl-D-Aspartate; Young Adult	2015
Vitamin D3 Supplemental Treatment for Mania in Youth with Bipolar Spectrum Disorders. Journal of child and adolescent psychopharmacology, 2015, Volume: 25, Issue:5 Topics: Adolescent; Affect; Bipolar Disorder; Child; Cholecalciferol; Dietary Supplements; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Humans; Male; Psychiatric Status Rating Scales; Treatment Outcome	2015
Exploring Genetic Variability at PI, GSK3, HPA, and Glutamatergic Pathways in Lithium Response: Association With IMPA2, INPP1, and GSK3B Genes. Journal of clinical psychopharmacology, 2015, Volume: 35, Issue:5 Topics: Adult; Antimanic Agents; Bipolar Disorder; Cross-Sectional Studies; Female; Genetic Variation; Genotype; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Lithium Compounds; Male; Middle Aged; Phosphoric Monoester Hydrolases; Polymorphism, Single Nucleotide; Prospective Studies; Retrospective Studies; Treatment Outcome	2015
A glutamatergic network mediates lithium response in bipolar disorder as defined by epigenome pathway analysis. Pharmacogenomics, 2015, Volume: 16, Issue:14 Topics: Antimanic Agents; Bipolar Disorder; Chromosome Mapping; Computer Simulation; Epigenesis, Genetic; Genome-Wide Association Study; Glutamic Acid; Humans; In Situ Hybridization; Lithium Compounds; Polymorphism, Single Nucleotide; Receptors, AMPA; RNA, Messenger	2015
A Longitudinal (6-week) 3T (1)H-MRS Study on the Effects of Lithium Treatment on Anterior Cingulate Cortex Metabolites in Bipolar Depression. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2015, Volume: 25, Issue:12 Topics: Adult; Antidepressive Agents; Bipolar Disorder; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Imaging, Three-Dimensional; Inositol; Lithium Compounds; Longitudinal Studies; Magnetic Resonance Spectroscopy; Male; Protons; Statistics, Nonparametric; Young Adult	2015
Anterior cingulate Glutamate-Glutamine cycle metabolites are altered in euthymic bipolar I disorder. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2015, Volume: 25, Issue:12 Topics: Adolescent; Adult; Analysis of Variance; Antidepressive Agents; Bipolar Disorder; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Male; Mass Spectrometry; Middle Aged; Young Adult	2015
Glutamatergic and HPA-axis pathway genes in bipolar disorder comorbid with alcohol- and substance use disorders. Metabolic brain disease, 2016, Volume: 31, Issue:1 Topics: Adolescent; Adult; Age of Onset; Alcoholism; Bipolar Disorder; Cohort Studies; Comorbidity; Female; Glutamic Acid; Humans; Hypothalamo-Hypophyseal System; Male; Middle Aged; Polymorphism, Single Nucleotide; Signal Transduction; Substance-Related Disorders; Young Adult	2016
Relationship between body mass index and hippocampal glutamate/glutamine in bipolar disorder. The British journal of psychiatry : the journal of mental science, 2016, Volume: 208, Issue:2 Topics: Adolescent; Adult; Bipolar Disorder; Body Mass Index; Body Weight; Case-Control Studies; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Linear Models; Magnetic Resonance Spectroscopy; Male; Young Adult	2016
The gene BRAF is underexpressed in bipolar subject olfactory neuroepithelial progenitor cells undergoing apoptosis. Psychiatry research, 2016, Feb-28, Volume: 236 Topics: Adult; Apoptosis; Bipolar Disorder; Case-Control Studies; Female; Glutamic Acid; Humans; Male; MAP Kinase Signaling System; Olfactory Receptor Neurons; Proto-Oncogene Proteins B-raf; Real-Time Polymerase Chain Reaction; Stem Cells	2016
Hippocampal neurochemical markers in bipolar disorder patients following the first-manic episode: A prospective 12-month proton magnetic resonance spectroscopy study. The Australian and New Zealand journal of psychiatry, 2017, Volume: 51, Issue:1 Topics: Adult; Aspartic Acid; Bipolar Disorder; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Male; Prospective Studies; Proton Magnetic Resonance Spectroscopy; Young Adult	2017
A sensitive and practical RP-HPLC-FLD for determination of the low neuroactive amino acid levels in body fluids and its application in depression. Neuroscience letters, 2016, Mar-11, Volume: 616 Topics: Aged; Aged, 80 and over; Amino Acids; Bipolar Disorder; Body Fluids; Case-Control Studies; Chromatography, High Pressure Liquid; Depression; Depressive Disorder; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Mood Disorders	2016
Evidence of altered membrane phospholipid metabolism in the anterior cingulate cortex and striatum of patients with bipolar disorder I: A multi-voxel (1)H MRS study. Journal of psychiatric research, 2016, Volume: 81 Topics: Adult; Aged; Bipolar Disorder; Corpus Striatum; Creatine; Female; Glutamic Acid; Gyrus Cinguli; Humans; Male; Middle Aged; Phospholipids; Proton Magnetic Resonance Spectroscopy; Psychiatric Status Rating Scales; Young Adult	2016
A targeted sequencing study of glutamatergic candidate genes in suicide attempters with bipolar disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2016, Volume: 171, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Bipolar Disorder; Calcium-Binding Proteins; Cell Adhesion Molecules, Neuronal; Excitatory Amino Acids; Female; Genetic Predisposition to Disease; Genetic Variation; Genome-Wide Association Study; Glutamic Acid; High-Throughput Nucleotide Sequencing; Humans; Male; Middle Aged; Nerve Tissue Proteins; Neural Cell Adhesion Molecules; Polymorphism, Single Nucleotide; Receptors, N-Methyl-D-Aspartate; Suicidal Ideation; Suicide; Suicide, Attempted	2016
Abnormal glutamatergic neurotransmission and neuronal-glial interactions in acute mania. Biological psychiatry, 2008, Oct-15, Volume: 64, Issue:8 Topics: Acute Disease; Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Cerebral Cortex; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Matched-Pair Analysis; Neuroglia; Neurons; Neurotransmitter Agents; Occipital Lobe; Parietal Lobe; Pilot Projects; Reference Values; Schizophrenia; Synaptic Transmission; Young Adult	2008
Investigation of G72 (DAOA) expression in the human brain. BMC psychiatry, 2008, Dec-11, Volume: 8 Topics: Bipolar Disorder; Brain; Carrier Proteins; Cell Line; Chromosome Mapping; Chromosomes, Human, Pair 13; D-Amino-Acid Oxidase; Enzyme Activation; Genetic Predisposition to Disease; Glutamic Acid; Humans; Intracellular Signaling Peptides and Proteins; Molecular Probe Techniques; Polymorphism, Genetic; Promoter Regions, Genetic; Protein Interaction Domains and Motifs; RNA, Messenger; Schizophrenia	2008
Neurochemical alterations in adolescent bipolar depression: a proton magnetic resonance spectroscopy pilot study of the prefrontal cortex. Journal of child and adolescent psychopharmacology, 2008, Volume: 18, Issue:6 Topics: Adolescent; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Aspartic Acid; Bipolar Disorder; Brain Chemistry; Child; Choline; Creatine; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Pilot Projects; Prefrontal Cortex	2008
Brain GABA levels in patients with bipolar disorder. Progress in neuro-psychopharmacology & biological psychiatry, 2009, Apr-30, Volume: 33, Issue:3 Topics: Adult; Bipolar Disorder; Brain; Brain Mapping; Case-Control Studies; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Spectrum Analysis	2009
Elevated metabolites within dorsolateral prefrontal cortex in rapid cycling bipolar disorder. Psychiatry research, 2009, Apr-30, Volume: 172, Issue:1 Topics: Adult; Aspartic Acid; Biomarkers; Bipolar Disorder; Brain; Choline; Creatine; Female; Functional Laterality; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex	2009
Increased choline-containing compounds in the orbitofrontal cortex and hippocampus in euthymic patients with bipolar disorder: a proton magnetic resonance spectroscopy study. Psychiatry research, 2009, Jun-30, Volume: 172, Issue:3 Topics: Adult; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Choline; Female; Frontal Lobe; Functional Laterality; Glutamic Acid; Glutamine; Glycerylphosphorylcholine; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphorylcholine; Psychiatric Status Rating Scales; Severity of Illness Index	2009
Rapid enhancement of glutamatergic neurotransmission in bipolar depression following treatment with riluzole. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:3 Topics: Adult; Bipolar Disorder; Female; Glutamic Acid; Gyrus Cinguli; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Riluzole; Synaptic Transmission; Time Factors; Treatment Outcome; Young Adult	2010
Markers of glutamate synaptic transmission and plasticity are increased in the anterior cingulate cortex in bipolar disorder. Biological psychiatry, 2010, Jun-01, Volume: 67, Issue:11 Topics: Adult; Aged; Analysis of Variance; Bipolar Disorder; Female; Functional Laterality; Genotype; Glutamic Acid; Glycoproteins; GPI-Linked Proteins; Gyrus Cinguli; Humans; In Situ Hybridization; Male; Middle Aged; Nerve Tissue Proteins; Netrins; Neuronal Plasticity; Neurons; Presynaptic Terminals; Reverse Transcriptase Polymerase Chain Reaction; Schizophrenia; Synaptic Transmission; Vesicular Glutamate Transport Protein 1	2010
Brain glutamatergic characteristics of pediatric offspring of parents with bipolar disorder. Psychiatry research, 2010, May-30, Volume: 182, Issue:2 Topics: Adolescent; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Brain Mapping; Child; Child of Impaired Parents; Cohort Studies; Female; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Pediatrics; Protons; Psychiatric Status Rating Scales	2010
Presynaptic glutamatergic dysfunction in bipolar disorder. Biological psychiatry, 2010, Jun-01, Volume: 67, Issue:11 Topics: Bipolar Disorder; Cerebral Cortex; Glutamic Acid; Humans; Neurons; Presynaptic Terminals	2010
Editorial: Etiological hypotheses of mental disorders at the molecular level. The Israel journal of psychiatry and related sciences, 2010, Volume: 47, Issue:1 Topics: Bipolar Disorder; Circadian Rhythm; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Mental Disorders; Receptors, N-Methyl-D-Aspartate; Risk Factors; Schizophrenia; Sleep	2010
Association of the brain-derived neurotrophic factor val66met polymorphism with magnetic resonance spectroscopic markers in the human hippocampus: in vivo evidence for effects on the glutamate system. European archives of psychiatry and clinical neuroscience, 2012, Volume: 262, Issue:1 Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Creatine; Female; Genetic Association Studies; Genotype; Glutamic Acid; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Memory; Methionine; Middle Aged; Multivariate Analysis; Polymorphism, Single Nucleotide; Protons; Schizophrenia; Valine; Verbal Learning	2012
Gene expression of GABA and glutamate pathway markers in the prefrontal cortex of non-suicidal elderly depressed patients. Journal of affective disorders, 2012, Volume: 138, Issue:3 Topics: Aged; Aged, 80 and over; Bipolar Disorder; Depressive Disorder, Major; Female; gamma-Aminobutyric Acid; Gene Expression; Glutamic Acid; Humans; Male; Prefrontal Cortex; Signal Transduction; Suicidal Ideation	2012
Association between three genetic polymorphisms of glutathione S-transferase Z1 (GSTZ1) and susceptibility to bipolar disorder. Psychiatry research, 2012, Jun-30, Volume: 198, Issue:1 Topics: Adolescent; Adult; Age Factors; Bipolar Disorder; Chi-Square Distribution; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Glutathione Transferase; Humans; Linkage Disequilibrium; Logistic Models; Lysine; Male; Middle Aged; Polymorphism, Single Nucleotide; Young Adult	2012
Platelet uptake of GABA and glutamate in patients with bipolar disorder. Bipolar disorders, 2012, Volume: 14, Issue:3 Topics: Adult; Aged; Analysis of Variance; Bipolar Disorder; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Psychometrics; Regression Analysis; Tritium; Young Adult	2012
Glutamatergic effects of divalproex in adolescents with mania: a proton magnetic resonance spectroscopy study. Journal of the American Academy of Child and Adolescent Psychiatry, 2012, Volume: 51, Issue:6 Topics: Adolescent; Antimanic Agents; Bipolar Disorder; Cerebral Cortex; Female; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Neurotransmitter Agents; Psychiatric Status Rating Scales; Remission Induction; Treatment Outcome; Valproic Acid	2012
Bcl-2 rs956572 polymorphism is associated with increased anterior cingulate cortical glutamate in euthymic bipolar I disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013, Volume: 38, Issue:3 Topics: Adolescent; Adult; Bipolar Disorder; Female; Glutamic Acid; Gyrus Cinguli; Humans; Male; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins c-bcl-2; Up-Regulation; Young Adult	2013
Acute mania is accompanied by elevated glutamate/glutamine levels within the left dorsolateral prefrontal cortex. Psychopharmacology, 2003, Volume: 168, Issue:3 Topics: Acute Disease; Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Receptors, Glutamate	2003
Some possible genetic parallels across alcoholism, bipolar disorder and schizophrenia. Journal of studies on alcohol, 2003, Volume: 64, Issue:2 Topics: Alcoholism; Bipolar Disorder; Catecholamines; Chromosome Deletion; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 22; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Schizophrenia	2003
Sequence analysis of ADARB1 gene in patients with familial bipolar disorder. Journal of affective disorders, 2004, Volume: 81, Issue:1 Topics: Adenosine Deaminase; Adolescent; Adult; Anticonvulsants; Bipolar Disorder; Chromosomes, Human, Pair 21; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Glutamic Acid; Humans; Male; Middle Aged; Molecular Sequence Data; Polymorphism, Genetic; Receptors, Glutamate; RNA Precursors; RNA-Binding Proteins; Sequence Analysis, DNA; Synaptic Transmission	2004
Bipolar mania and plasma amino acids: increased levels of glycine. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2006, Volume: 16, Issue:1 Topics: Adult; Aged; Bipolar Disorder; Case-Control Studies; Female; Glutamic Acid; Glycine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Tryptophan	2006
Altered cortical glutamatergic and GABAergic signal transmission with glial involvement in depression. Proceedings of the National Academy of Sciences of the United States of America, 2005, Oct-25, Volume: 102, Issue:43 Topics: Bipolar Disorder; Cerebral Cortex; Depressive Disorder, Major; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; gamma-Aminobutyric Acid; Gene Expression Profiling; Glutamate Plasma Membrane Transport Proteins; Glutamate-Ammonia Ligase; Glutamic Acid; Humans; In Situ Hybridization; Neuroglia; Oligonucleotide Array Sequence Analysis; Receptors, GABA-A; Signal Transduction	2005
DNA copy-number analysis in bipolar disorder and schizophrenia reveals aberrations in genes involved in glutamate signaling. Human molecular genetics, 2006, Mar-01, Volume: 15, Issue:5 Topics: A Kinase Anchor Proteins; Adaptor Proteins, Signal Transducing; Bipolar Disorder; Calcium Channels; Chromosome Aberrations; Chromosomes, Artificial, Bacterial; Cohort Studies; DNA Primers; Frontal Lobe; Gene Dosage; Genetic Variation; Genome, Human; GluK3 Kainate Receptor; Glutamic Acid; Humans; Nucleic Acid Hybridization; Receptors, Kainic Acid; Reverse Transcriptase Polymerase Chain Reaction; Schizophrenia; Signal Transduction	2006
Differences in brain chemistry in children and adolescents with attention deficit hyperactivity disorder with and without comorbid bipolar disorder: a proton magnetic resonance spectroscopy study. The American journal of psychiatry, 2006, Volume: 163, Issue:2 Topics: Adolescent; Age Factors; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Brain Chemistry; Child; Comorbidity; Creatine; Dopamine; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Inositol; Magnetic Resonance Spectroscopy; Phosphocreatine; Protons; Serotonin; Tissue Distribution	2006
Changes in [(3)H]-glutamate uptake into platelets from patients with bipolar I disorder. Psychiatry research, 2006, Mar-30, Volume: 141, Issue:3 Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Blood Platelets; Female; Glutamic Acid; Humans; Lithium Carbonate; Male; Synaptic Transmission	2006
Low cerebrospinal fluid glutamate and glycine in refractory affective disorder. Biological psychiatry, 2007, Jan-15, Volume: 61, Issue:2 Topics: Adult; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Chromatography, High Pressure Liquid; Depressive Disorder, Major; Drug Resistance; Electroconvulsive Therapy; Female; Glutamic Acid; Glycine; Humans; Male; Middle Aged; N-Methylaspartate; Statistics as Topic	2007
Effects of topiramate on the prepulse inhibition of the acoustic startle in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:2 Topics: Animals; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Brain; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Fructose; Glutamic Acid; Male; Neural Inhibition; Rats; Rats, Sprague-Dawley; Reflex, Startle; Schizophrenia; Synaptic Transmission; Topiramate	2007
Mania, glutamate/glutamine and risperidone in pediatric bipolar disorder: a proton magnetic resonance spectroscopy study of the anterior cingulate cortex. Journal of affective disorders, 2007, Volume: 99, Issue:1-3 Topics: Adolescent; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Child; Comorbidity; Creatine; Cross-Sectional Studies; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Psychiatric Status Rating Scales; Risperidone	2007
Decreased NR1, NR2A, and SAP102 transcript expression in the hippocampus in bipolar disorder. Brain research, 2007, Jan-05, Volume: 1127, Issue:1 Topics: Binding Sites; Binding, Competitive; Biomarkers; Bipolar Disorder; Down-Regulation; Female; Gene Expression Regulation; Glutamic Acid; Hippocampus; Humans; Male; Nuclear Proteins; Predictive Value of Tests; Presynaptic Terminals; Protein Transport; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Schizophrenia; Synaptic Transmission; Transcription Factors	2007
Reduction in occipital cortex gamma-aminobutyric acid concentrations in medication-free recovered unipolar depressed and bipolar subjects. Biological psychiatry, 2007, Mar-15, Volume: 61, Issue:6 Topics: Adult; Aged; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Brain Mapping; Depressive Disorder; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Matched-Pair Analysis; Middle Aged; Occipital Lobe; Reference Values	2007
Glutamine and glutamate levels in children and adolescents with bipolar disorder: a 4.0-T proton magnetic resonance spectroscopy study of the anterior cingulate cortex. Journal of the American Academy of Child and Adolescent Psychiatry, 2007, Volume: 46, Issue:4 Topics: Adolescent; Adult; Analysis of Variance; Bipolar Disorder; Child; Child, Preschool; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Neuroglia; Occipital Lobe; Protons; Psychotropic Drugs	2007
Increased anterior cingulate/medial prefrontal cortical glutamate and creatine in bipolar depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:12 Topics: Adult; Analysis of Variance; Antidepressive Agents; Bipolar Disorder; Creatine; Evaluation Studies as Topic; Female; Glutamic Acid; Gyrus Cinguli; Humans; Lamotrigine; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Protons; Triazines	2007
Synaptic P2X7 receptor regenerative-loop hypothesis for depression. The Australian and New Zealand journal of psychiatry, 2007, Volume: 41, Issue:7 Topics: Adenosine Triphosphate; Astrocytes; Bipolar Disorder; Brain; Cerebral Cortex; Depressive Disorder, Major; Genetic Predisposition to Disease; Glutamic Acid; Hippocampus; Humans; Infections; Interleukin-1beta; Microglia; Nerve Net; Nerve Regeneration; Polymorphism, Genetic; Receptors, AMPA; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Synapses; Synaptic Transmission; Toll-Like Receptors; Tumor Necrosis Factor-alpha	2007
Metabolic alterations in medication-free patients with bipolar disorder: a 3T CSF-corrected magnetic resonance spectroscopic imaging study. Psychiatry research, 2008, Feb-28, Volume: 162, Issue:2 Topics: Adolescent; Adult; Aspartic Acid; Basal Ganglia; Bipolar Disorder; Brain; Case-Control Studies; Caudate Nucleus; Corpus Striatum; Creatine; Cross-Sectional Studies; Dominance, Cerebral; Energy Metabolism; Female; Frontal Lobe; Glutamic Acid; Glutamine; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Reference Values	2008
Metabonomic analysis identifies molecular changes associated with the pathophysiology and drug treatment of bipolar disorder. Molecular psychiatry, 2009, Volume: 14, Issue:3 Topics: Adult; Analysis of Variance; Animals; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Creatine; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Matched-Pair Analysis; Metabolomics; Middle Aged; Prefrontal Cortex; Rats; Rats, Inbred WKY; Reference Values	2009
Glutamate as a spectroscopic marker of hippocampal structural plasticity is elevated in long-term euthymic bipolar patients on chronic lithium therapy and correlates inversely with diurnal cortisol. Molecular psychiatry, 2009, Volume: 14, Issue:7 Topics: Adult; Aged; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Choline; Circadian Rhythm; Creatine; Female; Glutamic Acid; Hippocampus; Humans; Hydrocortisone; Linear Models; Lithium Chloride; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuronal Plasticity; Saliva	2009
The antibipolar drug valproate mimics lithium in stimulating glutamate release and inositol 1,4,5-trisphosphate accumulation in brain cortex slices but not accumulation of inositol monophosphates and bisphosphates. Proceedings of the National Academy of Sciences of the United States of America, 1997, Apr-29, Volume: 94, Issue:9 Topics: Animals; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cerebral Cortex; Drug Interactions; Glutamic Acid; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lithium; Male; Mice; Mice, Inbred ICR; Molecular Mimicry; Receptors, N-Methyl-D-Aspartate; Valproic Acid	1997
Lithium acutely inhibits and chronically up-regulates and stabilizes glutamate uptake by presynaptic nerve endings in mouse cerebral cortex. Proceedings of the National Academy of Sciences of the United States of America, 1998, Jul-07, Volume: 95, Issue:14 Topics: Animals; Bipolar Disorder; Cerebral Cortex; Glutamic Acid; Lithium; Mice; Mice, Inbred ICR; Presynaptic Terminals; Up-Regulation	1998
Proton MR spectroscopy in children with bipolar affective disorder: preliminary observations. AJNR. American journal of neuroradiology, 2000, Volume: 21, Issue:5 Topics: Aspartic Acid; Basal Ganglia; Bipolar Disorder; Child; Choline; Creatine; Energy Metabolism; Frontal Lobe; Glutamic Acid; Glutamine; Humans; Lipid Metabolism; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Reference Values; Temporal Lobe	2000
Asymmetrical reductions of hippocampal NMDAR1 glutamate receptor mRNA in the psychoses. Neuroreport, 2001, Sep-17, Volume: 12, Issue:13 Topics: Bipolar Disorder; Depression; Down-Regulation; Female; Functional Laterality; Glutamic Acid; Hippocampus; Humans; Male; Middle Aged; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Schizophrenia; Sex Characteristics	2001