glutamic acid has been researched along with Autism Spectrum Disorder in 74 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 37 (50.00) | 24.3611 |
| 2020's | 37 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anashkina, AA; Erlykina, EI | 1 |
| Puts, NAJ; Sapey-Triomphe, LA; Temmerman, J; Wagemans, J | 1 |
| Bacova, Z; Bakos, J; Havranek, T; Meliskova, V | 1 |
| Akhtar, S; Ali, TA; Amjad, S; Bagga, P; Bhat, AA; Chawla, S; Fakhro, K; Frenneaux, MP; Haris, M; Hashem, S; Masoodi, T; Nisar, S; Reddy, R | 1 |
| Bonsi, P; Martella, G; Meringolo, M; Montanari, M | 1 |
| Dacko, M; Domschke, K; Düppers, AL; Ebert, D; Endres, D; Fangmeier, T; Lange, T; Maier, S; Nickel, K; Perlov, E; Riedel, A; Runge, K; Tebartz van Elst, L | 1 |
| Barash, J; Cheng, C; Kofke, WA; Li, M; Liu, Q; Shen, Y; Sheng, Z; Xie, Z | 1 |
| Amal, H; Hamoudi, W; Ojha, SK; Tripathi, MK | 1 |
| Ozawa, T; Sugimoto, N; Ueda, Y | 1 |
| Kim, J; Manning, MA; Niehaus, AD | 1 |
| Carey, C; Cash, D; Dunn, JT; Gee, A; Hader, S; Horder, J; Lythgoe, DJ; McAlonan, G; Mendez, MA; Murphy, D; Pereira, AC; Pretzsch, CM; Rotaru, DG; Sementa, T; Singh, N; Velthuis, H; Veronese, M | 1 |
| Arlicot, N; Barantin, L; Belzung, C; Bonnet-Brilhault, F; Briend, F; Chalon, S; Dupont, AC; Emond, P; Galineau, L; Gissot, V; Gomot, M; Houy-Durand, E; Laumonnier, F; Lefevre, A; Mavel, S; Nadal, L; Roussel, C; Roux, S; Santiago-Ribeiro, MJ; Tauber, C; Vercouillie, J | 1 |
| Dai, Y; Deng, S; Du, X; Feng, J; He, H; Ji, Y; Langley, C; Li, F; Li, WG; Liu, X; Luo, Q; Sahakian, BJ; Tang, Y; Wang, K; Yu, J; Zhang, J; Zhang, L; Zhou, X | 1 |
| Ambrosino, S; Banaschewski, T; Baumeister, S; Beckmann, CF; Bölte, S; Bourgeron, T; Buitelaar, JK; Charman, T; Dell'Acqua, F; Ecker, C; Forde, NJ; Hollestein, V; Holt, R; Jones, EJH; Loth, E; Mann, C; Mason, L; Moessnang, C; Murphy, DGM; Naaijen, J; Poelmans, G; Puts, NA; Schäfer, T; Tillmann, J | 1 |
| Chen, L; Cheng, Y; Du, Y; Li, YB; Wang, YL; Xv, CX; Yan, MC; Zhong, XL | 1 |
| Barantin, L; Bonnet-Brilhault, F; Briend, F; Cléry, H; Cottier, JP; Gomot, M; Houy-Durand, E | 1 |
| Albasher, G; Alonazi, M; Ben Bacha, A; El-Ansary, A; Kamalmaz, N; Khayyat, AIA | 1 |
| Abdelhakam, DA; Aboul-Ela, YM; Aboul-Fotouh, S; Ebeid, MA; Elnahas, EM; Habib, MZ; Negm, EA; Sadek, DR; Tarek, M | 1 |
| Demler, VF; Knolle, F; Sterner, EF; Wilson, M; Zimmer, C | 1 |
| Corrigan, N; Dager, S; Edden, R; Estes, A; Johnson, AJ; Kleinhans, NM; Richards, T; Shankland, E; Shusterman, D; St John, T | 1 |
| Crewther, DP; Enticott, PG; Ford, TC; Woods, W | 1 |
| Ajram, L; Daly, E; Edden, RAE; Heasman, M; Horder, J; Ivin, G; Lythgoe, D; McAlonan, GM; Mendez, MA; Murphy, DGM; Pretzsch, CM; Voinescu, B; Wichers, R; Williams, S | 1 |
| Saitow, F; Suzuki, H; Takumi, T | 1 |
| Dydak, U; Edmondson, DA; Keehn, B; McNally Keehn, R; Xia, P | 1 |
| Dai, Y; Deng, S; Du, X; Feng, J; Huang, CC; Ji, Y; Li, F; Lin, CP; Luo, Q; Sahakian, BJ; Shen, C; Tang, Y; Wang, K; Xu, M; Yu, J; Zhang, L | 1 |
| Kawada, K; Kuramoto, N; Mimori, S | 1 |
| Bernier, RA; Edden, RAE; Gerdts, J; Kolodny, T; Murray, SO; Schallmo, MP | 1 |
| Arckens, L; Bentea, E; Churchill, MJ; De Pauw, L; Declerck, NB; DePasquale, EAK; Funk, AJ; Hermans, E; Janssen, P; Lara, O; Massie, A; McCullumsmith, RE; Meshul, CK; Moore, C; O'Donovan, SM; Ris, L; Sato, H; Verbruggen, L; Villers, A | 1 |
| Kondo, HM; Lin, IF | 1 |
| Eltokhi, A; Merchan-Perez, A; Santuy, A; Sprengel, R | 1 |
| González-Mora, JL; Jiménez-Espinoza, C; Marcano Serrano, F | 1 |
| Banaschewski, T; Brandeis, D; Buitelaar, JK; Durston, S; Gooskens, B; Hohmann, S; Hollestein, V; Kaiser, A; Lythgoe, DJ; Naaijen, J; Oranje, B; Williams, SCR | 1 |
| Bortoletto, R; Colizzi, M; Costa, R; Zoccante, L | 1 |
| Branigan, H; Dauvermann, MR; Lawrie, SM; Roberts, N; Romaniuk, L; Siegel-Ramsay, JE; Stanfield, AC; Whalley, HC | 1 |
| Han, J; Shen, Y; Su, LD; Wang, N | 1 |
| Garner, CC; Jung, Y; Lee, K; Montgomery, JM; Vyas, Y | 1 |
| Crocetti, D; Deronda, A; Edden, RAE; Harris, AD; He, JL; Mikkelsen, M; Mostofsky, SH; Oeltzschner, G; Puts, NAJ; Wodka, EL | 1 |
| Bozzi, Y; Casarosa, S; Provenzano, G | 1 |
| Ajram, LA; Barker, GJ; Brennan, LP; Edden, RAE; Galanopoulos, A; Heasman, M; Horder, J; Ivin, G; Lythgoe, DJ; McAlonan, GM; Meek, D; Mendez, MA; Murphy, CM; Murphy, DGM; Robertson, DM; Tricklebank, MD; Wichers, RH; Williams, SC; Zinkstok, J | 1 |
| Bonsi, P; De Jaco, A; Martella, G; Meringolo, M; Pisani, A; Trobiani, L | 1 |
| Banaschewski, T; Dijkhuizen, RM; Dittmann, RW; Durston, S; Glennon, JC; Häge, A; K Buitelaar, J; Mechler, K; Murphy, D; Schweinfurth, N; Tactics Consortium, T; Williams, S | 1 |
| Arnesano, C; Herring, BE; Katritch, V; Sadybekov, A; Tian, C | 1 |
| Abrunhosa, A; Cai, Y; Castelo-Branco, M; Gonçalves, J; Leitão, RA; Sereno, J; Silva, AJ; Silva, AP; Violante, IR | 1 |
| Kery, R; Wang, X; Xiong, Q | 1 |
| Ackermann, J; Biscaldi, M; Bour, HS; Chiocchetti, AG; Cichon, S; Degenhardt, F; Duketis, E; Freitag, CM; Haslinger, D; Herms, S; Jarczok, T; Klauck, SM; Koch, I; Sachse, M; Waltes, R; Yousaf, A | 1 |
| Brandeis, D; Buitelaar, JK; Durston, S; Forde, NJ; Franke, B; Glennon, JC; Lythgoe, DJ; Naaijen, J; Williams, SC; Zwiers, MP | 1 |
| Carvalho Pereira, A; Castelo-Branco, M; Mouga, S; Oliveira, G; Violante, IR | 1 |
| Al-Ayadhi, L; Al-Marshoud, M; El-Ansary, A; Elkhawad, AO; Hamed, NO; Merghani, NM; Osman, MA; Qasem, H | 1 |
| Al-Ayadhi, L; Al-Otaish, H; Bjørklund, G; Chirumbolo, S; El-Ansary, A; Urbina, MA | 1 |
| Barker, GJ; Bruns, A; Horder, J; Künnecke, B; Mendez, MA; Murphy, DG; Petrinovic, MM; Spooren, W; Takumi, T | 1 |
| Khalifa, D; Raafat, O; Salem, D; Shahin, O | 1 |
| Brown, EA; Davis, TR; Fahnestock, M; Gniffke, EP; Lautz, JD; Neier, SC; Nicolini, C; Schrum, AG; Smith, SEP; Tashbook, N; VanSchoiack, AAW | 1 |
| Fernell, E | 1 |
| Durens, M; Lunden, JW; Nestor, MW; Phillips, AW | 1 |
| DU, L; Jia, FY; Li, HH; Wang, B; Yue, XJ | 1 |
| Ajram, L; Daly, E; Edden, RAE; Freyberg, J; Heasman, M; Horder, J; Ivin, G; Lythgoe, D; McAlonan, GM; Mendez, MA; Murphy, DGM; Pretzsch, CM; Voinescu, B; Wichers, R; Williams, S | 1 |
| Chen, J; Chen, Q; Feng, D; Feng, G; Fu, Z; Guo, B; Hu, H; Jia, F; Liu, H; Liu, Y; Lynn-Jones, T; Mao, H; Qi, C; Ren, K; Wang, W; Wu, S; Yang, J; Yao, H | 1 |
| Abu-Akel, A; Crewther, DP; Ford, TC | 1 |
| Ben-Ari, Y; Chiesa, M; Eftekhari, S; Ferrari, DC; Guimond, D; Lozovaya, N; Nardou, R; Tyzio, R | 1 |
| Friedman, LK; Kahen, BA | 1 |
| Chang, CL; Yang, P | 1 |
| Al-Ayadhi, L; El-Ansary, A | 1 |
| Chiu, SL; Huganir, RL; Sharma, K; Volk, L | 1 |
| Fung, LK; Hardan, AY | 1 |
| Baron-Cohen, S; Chakrabarti, B; Lai, MC; Roberts, D; Suckling, J; Young, AM | 1 |
| Cai, J; Ding, L; Wang, LZ; Xue, J; Zhang, JS | 1 |
| Banaschewski, T; Buitelaar, JK; Dijkhuizen, RM; Dittmann, RW; Franke, B; Häge, A; Lythgoe, DJ; Mechler, K; Williams, SC | 1 |
| Mu, D; Qu, Y; Zheng, Z; Zhu, T | 1 |
| Dickinson, A; Jones, M; Milne, E | 1 |
| Aldenkamp, AP; Barendse, EM; Drenthen, GS; Edden, RA; Hendriks, MP; Jansen, JF; Kessels, RP; Puts, NA; Thoonen, G; van Veenendaal, TM; Zinger, S | 1 |
| Baker, GB; Li, XM; Rauw, G; Wang, WQ; Zheng, HF | 1 |
| Amiri, H; Banaschewski, T; Boecker-Schlier, R; Brandeis, D; Buitelaar, JK; Durston, S; Franke, B; Glennon, JC; Lythgoe, DJ; Naaijen, J; Oranje, B; Ruf, M; Williams, SCR; Wolf, I; Zwiers, MP | 1 |
| Bralten, J; Buitelaar, JK; Franke, B; Glennon, JC; Naaijen, J; Poelmans, G | 1 |
| Fluegge, K | 1 |
22 review(s) available for glutamic acid and Autism Spectrum Disorder
| Article | Year |
|---|---|
Molecular Mechanisms of Aberrant Neuroplasticity in Autism Spectrum Disorders (Review).
Topics: Amino Acids; Autism Spectrum Disorder; Glutamic Acid; Humans; Neuronal Plasticity; Oxidative Stress | 2021 |
The role of selected postsynaptic scaffolding proteins at glutamatergic synapses in autism-related animal models.
Topics: Animals; Autism Spectrum Disorder; Disease Models, Animal; Glutamic Acid; Guanylate Kinases; Homer Scaffolding Proteins; Membrane Proteins; Mice; Nerve Tissue Proteins; Synapses | 2021 |
Genetics of glutamate and its receptors in autism spectrum disorder.
Topics: Animals; Autism Spectrum Disorder; Brain; Disease Models, Animal; Glutamic Acid; Synaptic Transmission | 2022 |
Autism Spectrum Disorder: Focus on Glutamatergic Neurotransmission.
Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Gastrointestinal Microbiome; Glutamic Acid; Humans; Synaptic Transmission | 2022 |
Phenotypic variability in RERE-related disorders and the first report of an inherited variant.
Topics: Arginine; Autism Spectrum Disorder; Biological Variation, Population; Carrier Proteins; Dipeptides; Female; Glutamic Acid; Humans; Intellectual Disability; Musculoskeletal Abnormalities; Neurodevelopmental Disorders; Phenotype | 2022 |
Neurometabolite levels in the brains of patients with autism spectrum disorders: A meta-analysis of proton magnetic resonance spectroscopy studies (N = 1501).
Topics: Aspartic Acid; Autism Spectrum Disorder; Brain; Choline; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Proton Magnetic Resonance Spectroscopy | 2023 |
Possibility that the Onset of Autism Spectrum Disorder is Induced by Failure of the Glutamine-Glutamate Cycle.
Topics: Autism Spectrum Disorder; Brain; Endoplasmic Reticulum Stress; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Humans; Neurogenesis; Neuroglia; Neurons; Plant Extracts; Tea | 2021 |
Glutamatergic Dysfunction and Synaptic Ultrastructural Alterations in Schizophrenia and Autism Spectrum Disorder: Evidence from Human and Rodent Studies.
Topics: Animals; Autism Spectrum Disorder; Biomarkers; Disease Models, Animal; Disease Susceptibility; Glutamic Acid; Humans; Mitochondria; Neuronal Plasticity; Neurons; Receptors, Glutamate; Rodentia; Schizophrenia; Synapses | 2020 |
Palmitoylethanolamide and Its Biobehavioral Correlates in Autism Spectrum Disorder: A Systematic Review of Human and Animal Evidence.
Topics: Amides; Animals; Apoptosis; Autism Spectrum Disorder; Brain; Down-Regulation; Endocannabinoids; Ethanolamines; Glutamic Acid; Humans; Immune System Phenomena; Inflammation; Mitochondria; Neuroprotective Agents; Palmitic Acids; PPAR alpha; Receptors, Cannabinoid; Signal Transduction | 2021 |
Group 1 Metabotropic Glutamate Receptors in Neurological and Psychiatric Diseases: Mechanisms and Prospective.
Topics: Alzheimer Disease; Autism Spectrum Disorder; Glutamic Acid; Humans; Mental Disorders; Parkinson Disease | 2022 |
Neurobiological bases of autism-epilepsy comorbidity: a focus on excitation/inhibition imbalance.
Topics: Animals; Autism Spectrum Disorder; Comorbidity; Cortical Excitability; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Neural Inhibition | 2018 |
Glutamatergic Agents in the Treatment of Compulsivity and Impulsivity in Child and Adolescent Psychiatry: a Systematic Review of the Literature.
Topics: Acetylcysteine; Adolescent; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Brain; Child; Corpus Striatum; Excitatory Amino Acid Agents; Glutamic Acid; Humans; Memantine; Obsessive-Compulsive Disorder; Randomized Controlled Trials as Topic; Receptors, Glutamate; Risk Assessment; Treatment Outcome | 2018 |
Synaptopathology in autism spectrum disorders: Complex effects of synaptic genes on neural circuits.
Topics: Animals; Autism Spectrum Disorder; Brain; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Synapses; Synaptic Transmission | 2018 |
Cortical interneuron function in autism spectrum condition.
Topics: Animals; Autism Spectrum Disorder; Cerebral Cortex; Electroencephalography; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Induced Pluripotent Stem Cells; Interneurons | 2019 |
[A review on the role of γ-aminobutyric acid signaling pathway in autism spectrum disorder].
Topics: Animals; Autism Spectrum Disorder; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Signal Transduction | 2018 |
Glutamate-mediated signaling and autism spectrum disorders: emerging treatment targets.
Topics: Animals; Autism Spectrum Disorder; Drug Design; Glutamic Acid; Humans; Molecular Targeted Therapy; Neuronal Plasticity; Pluripotent Stem Cells; Receptors, Glutamate; Signal Transduction; Synaptic Transmission | 2014 |
Glutamate synapses in human cognitive disorders.
Topics: Animals; Autism Spectrum Disorder; Cognition Disorders; Genetic Predisposition to Disease; Glutamic Acid; Humans; Intellectual Disability; Models, Neurological; Schizophrenia; Synapses | 2015 |
Developing Medications Targeting Glutamatergic Dysfunction in Autism: Progress to Date.
Topics: Animals; Autism Spectrum Disorder; Excitatory Amino Acid Agents; Glutamic Acid; Humans | 2015 |
From molecules to neural morphology: understanding neuroinflammation in autism spectrum condition.
Topics: Amniotic Fluid; Animals; Antigens, Surface; Autism Spectrum Disorder; Autoantibodies; Body Fluids; Brain; Brain Chemistry; Chemokines; Cytokines; Female; Glutamic Acid; Haplorhini; HLA Antigens; Humans; Immunity, Maternally-Acquired; Inflammation; Inflammation Mediators; Lipopolysaccharides; Maternal-Fetal Exchange; Mice; Nerve Tissue Proteins; Neuroglia; Neuroimaging; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Signal Transduction | 2016 |
Blood Glutamate Levels in Autism Spectrum Disorder: A Systematic Review and Meta-Analysis.
Topics: Autism Spectrum Disorder; Chromatography, High Pressure Liquid; Glutamic Acid; Humans; Tandem Mass Spectrometry | 2016 |
Measuring neural excitation and inhibition in autism: Different approaches, different findings and different interpretations.
Topics: Adult; Animals; Autism Spectrum Disorder; Brain; Electroencephalography; Gamma Rhythm; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetoencephalography; Neural Inhibition; Young Adult | 2016 |
Body fluid levels of neuroactive amino acids in autism spectrum disorders: a review of the literature.
Topics: Amino Acids; Autism Spectrum Disorder; Body Fluids; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycine; Humans; Serine; Taurine; Tryptophan | 2017 |
5 trial(s) available for glutamic acid and Autism Spectrum Disorder
| Article | Year |
|---|---|
Improved symptoms following bumetanide treatment in children aged 3-6 years with autism spectrum disorder: a randomized, double-blind, placebo-controlled trial.
Topics: Autism Spectrum Disorder; Autistic Disorder; Bumetanide; Child; Child, Preschool; gamma-Aminobutyric Acid; Glutamic Acid; Humans | 2021 |
Effects of cannabidivarin (CBDV) on brain excitation and inhibition systems in adults with and without Autism Spectrum Disorder (ASD): a single dose trial during magnetic resonance spectroscopy.
Topics: Adult; Autism Spectrum Disorder; Basal Ganglia; Cannabinoids; Cross-Over Studies; Double-Blind Method; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gray Matter; Humans; Inhibition, Psychological; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; White Matter; Young Adult | 2019 |
Symptom improvement in children with autism spectrum disorder following bumetanide administration is associated with decreased GABA/glutamate ratios.
Topics: Autism Spectrum Disorder; Autistic Disorder; Bumetanide; Child; Child, Preschool; gamma-Aminobutyric Acid; Glutamic Acid; Humans | 2020 |
Effects of cannabidiol on brain excitation and inhibition systems; a randomised placebo-controlled single dose trial during magnetic resonance spectroscopy in adults with and without autism spectrum disorder.
Topics: Adult; Autism Spectrum Disorder; Basal Ganglia; Cannabidiol; Double-Blind Method; gamma-Aminobutyric Acid; Glutamic Acid; Gray Matter; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; White Matter; Young Adult | 2019 |
Glutamatergic medication in the treatment of obsessive compulsive disorder (OCD) and autism spectrum disorder (ASD) - study protocol for a randomised controlled trial.
Topics: Adolescent; Adolescent Behavior; Autism Spectrum Disorder; Brain; Child; Child Behavior; Clinical Protocols; Double-Blind Method; Europe; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Male; Memantine; Neuroimaging; Obsessive-Compulsive Disorder; Psychiatric Status Rating Scales; Research Design; Time Factors; Treatment Outcome | 2016 |
47 other study(ies) available for glutamic acid and Autism Spectrum Disorder
| Article | Year |
|---|---|
Prediction learning in adults with autism and its molecular correlates.
Topics: Adult; Autism Spectrum Disorder; Autistic Disorder; Bayes Theorem; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy | 2021 |
Increased prefrontal GABA concentrations in adults with autism spectrum disorders.
Topics: Adult; Autism Spectrum Disorder; Creatine; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Prefrontal Cortex | 2022 |
Fentanyl induces autism-like behaviours in mice by hypermethylation of the glutamate receptor gene Grin2b.
Topics: Analgesics, Opioid; Animals; Autism Spectrum Disorder; Autistic Disorder; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; Fentanyl; Glutamic Acid; Male; Mice; Naloxone; Narcotic Antagonists; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu | 2022 |
A cross-talk between nitric oxide and the glutamatergic system in a Shank3 mouse model of autism.
Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Disease Models, Animal; Glutamic Acid; Mice; Microfilament Proteins; Nerve Tissue Proteins; Nitric Oxide; Proteome | 2022 |
Increased spine PIP3 is sequestered from dendritic shafts.
Topics: Autism Spectrum Disorder; Fluorescent Dyes; Glutamic Acid; Humans; Neuronal Plasticity; Pyramidal Cells; Spine | 2022 |
From bench to bedside: The mGluR5 system in people with and without Autism Spectrum Disorder and animal model systems.
Topics: Adult; Animals; Autism Spectrum Disorder; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Membrane Proteins; Mice; Microfilament Proteins; Nerve Tissue Proteins; Parvalbumins; Receptor, Metabotropic Glutamate 5 | 2022 |
Glutamatergic synapse in autism: a complex story for a complex disorder.
Topics: Adolescent; Adult; Animals; Autism Spectrum Disorder; Autistic Disorder; Brain; Child; Female; Glutamic Acid; Humans; Male; Pregnancy; Rats; Synapses; Valproic Acid | 2023 |
Excitatory/inhibitory imbalance in autism: the role of glutamate and GABA gene-sets in symptoms and cortical brain structure.
Topics: Adolescent; Adult; Autism Spectrum Disorder; Autistic Disorder; Brain; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Transcriptome | 2023 |
Glutamate levels of the right and left anterior cingulate cortex in autistics adults.
Topics: Adult; Autism Spectrum Disorder; Autistic Disorder; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy | 2023 |
Unveiling sex-based differences in developing propionic acid-induced features in mice as a rodent model of ASD.
Topics: Animals; Autism Spectrum Disorder; Female; Glutamic Acid; Male; Mice; Neuroinflammatory Diseases; Rodentia; Sex Characteristics | 2023 |
Risperidone impedes glutamate excitotoxicity in a valproic acid rat model of autism: Role of ADAR2 in AMPA GluA2 RNA editing.
Topics: Adenosine Deaminase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autism Spectrum Disorder; Autistic Disorder; Disease Models, Animal; Female; Glutamic Acid; Pregnancy; Rats; Receptors, AMPA; Risperidone; RNA; RNA Editing; Valproic Acid | 2023 |
Association between increased anterior cingulate glutamate and psychotic-like experiences, but not autistic traits in healthy volunteers.
Topics: Autism Spectrum Disorder; Female; Glutamic Acid; Gyrus Cinguli; Healthy Volunteers; Humans; Magnetic Resonance Spectroscopy | 2023 |
Relationships between GABA, glutamate, and GABA/glutamate and social and olfactory processing in children with autism spectrum disorder.
Topics: Autism Spectrum Disorder; Child; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Smell | 2023 |
Cortical excitation-inhibition ratio mediates the effect of pre-attentive auditory processing deficits on interpersonal difficulties.
Topics: Adolescent; Adult; Auditory Perception; Autism Spectrum Disorder; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Interpersonal Relations; Magnetic Resonance Imaging; Magnetoencephalography; Male; Neural Inhibition; Neuropsychological Tests; Schizotypal Personality Disorder; Social Perception; Temporal Lobe; Young Adult | 2020 |
Change in serotonergic modulation contributes to the synaptic imbalance of neuronal circuit at the prefrontal cortex in the 15q11-13 duplication mouse model of autism.
Topics: Animals; Autism Spectrum Disorder; Cortical Excitability; Disease Models, Animal; DNA Copy Number Variations; GABAergic Neurons; gamma-Aminobutyric Acid; Glutamic Acid; Long-Term Potentiation; Male; Membrane Potentials; Mice, Inbred C57BL; Prefrontal Cortex; Pyramidal Cells; Receptors, Serotonin, 5-HT2; Serotonin; Synapses | 2020 |
A Magnetic Resonance Spectroscopy Study of Superior Visual Search Abilities in Children with Autism Spectrum Disorder.
Topics: Adolescent; Aspartic Acid; Attention; Autism Spectrum Disorder; Brain; Child; Creatine; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Visual Perception | 2020 |
Concentrations of Cortical GABA and Glutamate in Young Adults With Autism Spectrum Disorder.
Topics: Autism Spectrum Disorder; Bayes Theorem; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Young Adult | 2020 |
Corticostriatal dysfunction and social interaction deficits in mice lacking the cystine/glutamate antiporter.
Topics: Animals; Antiporters; Autism Spectrum Disorder; Cystine; Glutamic Acid; Mice; Proteomics; Social Interaction | 2021 |
Excitation-inhibition balance and auditory multistable perception are correlated with autistic traits and schizotypy in a non-clinical population.
Topics: Adolescent; Adult; Auditory Cortex; Auditory Perception; Autism Spectrum Disorder; Child; Female; Glutamic Acid; Glutamine; Humans; Inhibition, Psychological; Male; Schizophrenia; Schizotypal Personality Disorder; Verbal Learning; Young Adult | 2020 |
Topics: Adult; Aspartic Acid; Astrocytes; Autism Spectrum Disorder; Biomarkers; Cerebral Cortex; Dipeptides; Female; Glutamic Acid; Humans; Male; Neurons; Oligodendroglia; Proton Magnetic Resonance Spectroscopy; Young Adult | 2021 |
Developmental changes in fronto-striatal glutamate and their association with functioning during inhibitory control in autism spectrum disorder and obsessive compulsive disorder.
Topics: Adolescent; Autism Spectrum Disorder; Corpus Striatum; Glutamic Acid; Humans; Magnetic Resonance Imaging; Obsessive-Compulsive Disorder | 2021 |
Glutamate and functional connectivity - support for the excitatory-inhibitory imbalance hypothesis in autism spectrum disorders.
Topics: Adult; Autism Spectrum Disorder; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Male; Proton Magnetic Resonance Spectroscopy | 2021 |
In vitro zinc supplementation alters synaptic deficits caused by autism spectrum disorder-associated Shank2 point mutations in hippocampal neurons.
Topics: Animals; Animals, Newborn; Autism Spectrum Disorder; Dietary Supplements; Female; Glutamic Acid; Hippocampus; Male; Nerve Tissue Proteins; Neurons; Point Mutation; Rats; Synapses; Zinc | 2021 |
Region-specific elevations of glutamate + glutamine correlate with the sensory symptoms of autism spectrum disorders.
Topics: Autism Spectrum Disorder; Child; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy | 2021 |
Shifting brain inhibitory balance and connectivity of the prefrontal cortex of adults with autism spectrum disorder.
Topics: Adult; Autism Spectrum Disorder; Brain; Brain Mapping; Excitatory Amino Acid Antagonists; Functional Neuroimaging; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Neural Pathways; Prefrontal Cortex; Riluzole | 2017 |
The neurobiological bases of autism spectrum disorders: the R451C-neuroligin 3 mutation hampers the expression of long-term synaptic depression in the dorsal striatum.
Topics: Animals; Autism Spectrum Disorder; Cell Adhesion Molecules, Neuronal; Disease Models, Animal; Electroencephalography; Endocannabinoids; Excitatory Postsynaptic Potentials; GABA Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; Glutamic Acid; Long-Term Synaptic Depression; Male; Membrane Proteins; Mice; Mice, Transgenic; Neostriatum; Nerve Tissue Proteins; Patch-Clamp Techniques; Picrotoxin; Receptor, Cannabinoid, CB1 | 2018 |
An autism spectrum disorder-related de novo mutation hotspot discovered in the GEF1 domain of Trio.
Topics: Animals; Autism Spectrum Disorder; Female; Genetic Predisposition to Disease; Glutamic Acid; Guanine Nucleotide Exchange Factors; Humans; In Vitro Techniques; Male; Mutation; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Synapses | 2017 |
Testing the excitation/inhibition imbalance hypothesis in a mouse model of the autism spectrum disorder: in vivo neurospectroscopy and molecular evidence for regional phenotypes.
Topics: Animals; Autism Spectrum Disorder; Disease Models, Animal; DNA-Binding Proteins; Female; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Inhibition, Psychological; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Knockout; Nervous System Physiological Phenomena; Neurofibromin 1; Organ Specificity; Receptors, GABA; Viral Proteins | 2017 |
Common functional variants of the glutamatergic system in Autism spectrum disorder with high and low intellectual abilities.
Topics: Autism Spectrum Disorder; Child; Female; Genetic Association Studies; Glutamic Acid; Humans; Intellectual Disability; Intelligence Tests; Male; Polymorphism, Single Nucleotide | 2018 |
Striatal structure and its association with N-Acetylaspartate and glutamate in autism spectrum disorder and obsessive compulsive disorder.
Topics: Adolescent; Aspartic Acid; Autism Spectrum Disorder; Child; Corpus Striatum; Female; Functional Laterality; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Obsessive-Compulsive Disorder; Organ Size; Proton Magnetic Resonance Spectroscopy | 2018 |
Medial Frontal Lobe Neurochemistry in Autism Spectrum Disorder is Marked by Reduced N-Acetylaspartate and Unchanged Gamma-Aminobutyric Acid and Glutamate + Glutamine Levels.
Topics: Adolescent; Aspartic Acid; Autism Spectrum Disorder; Biomarkers; Child; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex | 2018 |
Understanding the roles of glutamine synthetase, glutaminase, and glutamate decarboxylase autoantibodies in imbalanced excitatory/inhibitory neurotransmission as etiological mechanisms of autism.
Topics: Autism Spectrum Disorder; Autoantibodies; Child; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Humans; Male; Synaptic Transmission | 2018 |
Relationship between absolute and relative ratios of glutamate, glutamine and GABA and severity of autism spectrum disorder.
Topics: Adolescent; Autism Spectrum Disorder; Biomarkers; Child; Cognition; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Male; Severity of Illness Index; Social Behavior | 2018 |
Glutamate and GABA in autism spectrum disorder-a translational magnetic resonance spectroscopy study in man and rodent models.
Topics: Adult; Animals; Autism Spectrum Disorder; Brain; Corpus Striatum; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Mice, Inbred C57BL; Mice, Transgenic; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Rats, Transgenic | 2018 |
Serum glutamate was elevated in children aged 3-10 years with autism spectrum disorders when they were compared with controls.
Topics: Autism Spectrum Disorder; Biomarkers; Case-Control Studies; Child; Child, Preschool; Female; Glutamic Acid; Humans; Male | 2019 |
Clustering the autisms using glutamate synapse protein interaction networks from cortical and hippocampal tissue of seven mouse models.
Topics: Animals; Autism Spectrum Disorder; Cluster Analysis; Disease Models, Animal; Female; Frontal Lobe; Genotype; Glutamic Acid; Hippocampus; Male; Mice; Protein Interaction Maps; Proteomics; Synapses | 2018 |
Further studies of GABA and Glutamate imbalances in autism are important challenges for future research.
Topics: Autism Spectrum Disorder; Autistic Disorder; Child; Child, Preschool; gamma-Aminobutyric Acid; Glutamic Acid; Humans | 2019 |
Anterior cingulate cortex dysfunction underlies social deficits in Shank3 mutant mice.
Topics: Animals; Autism Spectrum Disorder; Dioxoles; Disease Models, Animal; Glutamic Acid; Grooming; Gyrus Cinguli; Interpersonal Relations; Mice; Mice, Inbred C57BL; Mice, Knockout; Microfilament Proteins; Mutation; Nerve Tissue Proteins; Optogenetics; Piperidines; Pyramidal Cells; Receptors, AMPA; Social Behavior; Synapses | 2019 |
Psychosocial deficits across autism and schizotypal spectra are interactively modulated by excitatory and inhibitory neurotransmission.
Topics: Adolescent; Adult; Attention; Autism Spectrum Disorder; Cognition; Female; gamma-Aminobutyric Acid; Glutamic Acid; Healthy Volunteers; Humans; Interpersonal Relations; Male; Proton Magnetic Resonance Spectroscopy; Schizotypal Personality Disorder; Social Skills; Synaptic Transmission; Temporal Lobe; Young Adult | 2020 |
Enhanced Glutamatergic Currents at Birth in Shank3 KO Mice.
Topics: Animals; Animals, Newborn; Autism Spectrum Disorder; CA3 Region, Hippocampal; Disease Models, Animal; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Mice; Mice, Knockout; Microfilament Proteins; Nerve Tissue Proteins; Patch-Clamp Techniques; Pyramidal Cells | 2019 |
Chronic subconvulsive activity during early postnatal life produces autistic behavior in the absence of neurotoxicity in the juvenile weanling period.
Topics: Animals; Anxiety; Autism Spectrum Disorder; Behavior, Animal; Disease Models, Animal; Female; Glutamic Acid; Interpersonal Relations; Kainic Acid; Male; Phenotype; Rats; Sex Factors; Social Behavior; Social Environment | 2019 |
GABAergic/glutamatergic imbalance relative to excessive neuroinflammation in autism spectrum disorders.
Topics: Adolescent; Animals; Autism Spectrum Disorder; Biomarkers; Child; Child, Preschool; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Inflammation; Interleukin-6; Male; Mice; Rats; Tumor Necrosis Factor-alpha | 2014 |
Elevated plasma levels of glutamate in children with autism spectrum disorders.
Topics: Area Under Curve; Autism Spectrum Disorder; Blood Chemical Analysis; Child, Preschool; Chromatography, Liquid; Female; Glutamic Acid; Humans; Logistic Models; Male; Multivariate Analysis; Psychiatric Status Rating Scales; ROC Curve; Severity of Illness Index; Tandem Mass Spectrometry | 2016 |
Altered neurotransmitter metabolism in adolescents with high-functioning autism.
Topics: Adolescent; Autism Spectrum Disorder; Creatine; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Proton Magnetic Resonance Spectroscopy | 2016 |
Fronto-Striatal Glutamate in Autism Spectrum Disorder and Obsessive Compulsive Disorder.
Topics: Adolescent; Autism Spectrum Disorder; Child; Corpus Striatum; Female; Frontal Lobe; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Obsessive-Compulsive Disorder | 2017 |
Glutamatergic and GABAergic gene sets in attention-deficit/hyperactivity disorder: association to overlapping traits in ADHD and autism.
Topics: Adolescent; Amino Acid Transport System y+L; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Autistic Disorder; Calcium-Binding Proteins; Child; Child, Preschool; Female; Fusion Regulatory Protein 1, Light Chains; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Nerve Tissue Proteins; Receptors, AMPA; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Severity of Illness Index | 2017 |
The BTBR Mouse, Sociability, and Reduced Glutamate Release: A Role for Endogenous Dynorphin?
Topics: Animals; Autism Spectrum Disorder; Behavior, Animal; Disease Models, Animal; Dynorphins; Glutamic Acid; Mice, Inbred C57BL; Mice, Inbred Strains; Social Behavior | 2017 |