Compounds > glutamic acid

glutamic acid and Aura

glutamic acid has been researched along with Aura in 483 studies

Research

Studies (483)

TimeframeStudies, this research(%)All Research%
pre-199035 (7.25)18.7374
1990's82 (16.98)18.2507
2000's180 (37.27)29.6817
2010's139 (28.78)24.3611
2020's47 (9.73)2.80

Authors

AuthorsStudies
Dos Santos, WF; Fontana, ACK; Green, JL1
Aydin, E; Hotz, AL; Jamali, A; Jurisch-Yaksi, N; Lalla, L; Myren-Svelstad, S; Neuhauss, SCF; Niklaus, S; Rieser, NN; Yaksi, E1
Fujita, Y; Hashiguchi, M; Kohmura, E; Kohta, M; Maeyama, M; Nagashima, H; Nakai, T; Sasayama, T; Somiya, Y; Tanaka, H; Tanaka, K; Uozumi, Y1
Alcoreza, O; Campbell, SL; Jagarlamudi, S; Savoia, A; Sontheimer, H1
Fukuyama, K; Okada, M1
Bao, YH; Chen, MJ; He, JH; Huang, BJ; Kwan, P; Li, YP; Li, ZC; Mao, YL; Qiao, JD; Ye, ZJ; Zhang, JM; Zhang, WJ1
Chen, D; Gan, CL; Gu, X; Hu, L; Lee, TH; Li, R; Mei, Y; Shui, X; Tian, Y; Wang, J; Wang, L; Zhang, M; Zhang, T; Zou, Y1
Bentley, R; Hu, G; Jiang, X; Lowe, S; Mei, H; Sun, C; Wu, Y; Xie, R; Zhao, W1
Chen, S; Das, S; Davis, KA; Detre, JA; Elliott, MA; Gibson, A; Hadar, P; Lucas, A; Nanga, RPR; Oechsel, K; Reddy, R; Stein, JM1
Alijanpour, S; Ghafouri-Fard, S; Miryounesi, M1
Bedner, P; Henneberger, C; Henning, L; Steinhäuser, C; Unichenko, P1
Mai, D; Qu, Q; Qu, S; Ren, S; Wang, J; Zhang, W; Zhang, Y1
Bayat, A; Bobylova, M; Bonanni, P; Cerulli Irelli, E; Ceulemans, B; Coppola, A; Cuccurullo, C; De Wachter, M; Di Bonaventura, C; Feucht, M; Fuchs, A; Gröppel, G; Heimer, G; Herdt, B; Kluger, G; Kulikova, S; Lerman Sagie, T; Mukhin, K; Nicassio, S; Nissenkorn, A; Orsini, A; Panagiotou, M; Pringsheim, M; Puest, B; Pylaeva, O; Ramantani, G; Ricciardelli, P; Russo, A; Schubert-Bast, S; Stark, B; Striano, P; Tsekoura, M; van Baalen, A; von Stülpnagel, C1
Holton, KF; Kao, A; Sarlo, GL1
Alves, M; Boison, D; Purnell, BS1
Cai, X; Dai, Y; Fan, P; He, E; Mo, F; Song, Y; Wang, Y; Wu, Y; Xie, J; Xing, Y; Xu, Z; Yang, G1
Costa, B; Vale, N1
Jayalakshmi, S; Madhamanchi, K; Madhamanchi, P; Panigrahi, M; Patil, A; Phanithi, PB1
Goyette, MJ; Holton, K; Murray, SL; Saldanha, CJ1
Shende, P; Trivedi, R1
Callai, EMM; Catarina, LS; da Silva Torres, IL; de Oliveira Marques, C; Fróes, F; Gonçalves, CA; Leal, MB; Moreira, AP; Ponzoni, D; Puricelli, E; Quevedo, AS; Vizuete, AFK; Zin, LEF1
Ciltas, AC; Güneş, H; Toy, CE; Yaprak, M1
Aydin, E; Cosacak, MI; Deneubourg, C; Diaz Verdugo, C; Jurisch-Yaksi, N; Kawakami, K; Kizil, C; Muto, A; Myren-Svelstad, S; Pelgrims, R; Van Hoeymissen, E; Vancraeynest, J; Vanderhaeghe, S; Yaksi, E1
Kullmann, DM; Walker, MC1
Aviramd, I; Biton, Y; Braunstein, D; Rabinovitch, A1
Akanuma, SI; Bauer, B; Doods, H; Hartz, AMS; Hosoya, KI; Kryscio, RJ; Pekcec, A; Soldner, ELB1
Bauer, B; Hartz, AMS; Kryscio, R; Pekcec, A; Rempe, RG; Schlichtiger, J; Soldner, ELB1
Bao, YH; Chen, DY; Chen, HS; Chen, Z; Cui, TT; Fukunaga, K; Gong, DM; Han, F; He, Y; Liu, XX; Lu, NN; Lu, YM; Lu, YP; Shao, LX; Shi, WX; Sun, NH; Wu, G; Yang, L1
Karyakin, VB; Malkin, SL; Postnikova, TY; Romanova, IV; Smolensky, IV; Zaitsev, AV; Zakharova, MV; Zavyalov, V; Zubareva, OE1
Kwan, P; Nicolo, JP; O'Brien, TJ1
Ai, Y; Alcala, R; Boychuk, JA; Butler, CR; Gerhardt, GA; Huettl, P; Jakobsson, J; Pomerleau, F; Slevin, JT; Smith, BN; Whiteheart, SW1
Weller, M; Wirsching, HG1
Krystal, JH1
Hanada, T1
Alese, OO; Mabandla, MV; Mkhize, NV; Ngoupaye, GT; Rakgantsho, C; Zulu, S1
Colangeli, R; Hill, MN; Morena, M; Pittman, QJ; Teskey, GC1
Desai, MJ; Kapinos, G; Valsamis, HA; Weiss, SA1
Bardakjian, BL; Breton, VL; Carlen, PL; Chinvarun, Y; Del Campo, JM; Dufour, S1
Ametamey, SM; Cumming, P; Kim, JH; Marton, J1
Moreira, JD; Müller, AP; Porciúncula, LO; Siqueira, LV; Souza, DO; Vinadé, L1
Desmond, PM; Gonen, OM; Kwan, P; Lui, E; Moffat, BA; O'Brien, TJ1
Chen, Q; Chen, Y; Feng, Z; Huang, H; Peng, Y; Wang, J; Xu, Z; Zeng, J; Zhang, H; Zhang, J; Zhou, X1
Akyuz, E; Angelopoulou, E; Eroglu, E; Kullu, I; Paudel, YN; Polat, AK1
Bai, S; Ding, J; Guan, Y; Hao, Y; Hong, R; Li, Z; Peng, J1
Crespo, M; León-Navarro, DA; Martín, M1
Brigati, G; De Angelis, LC; Maghnie, M; Malova, M; Massirio, P; Minghetti, D; Parodi, A; Polleri, G; Ramenghi, LA; Rossi, A; Traggiai, C1
Chen, WB; Huang, ZH; Lee, D; Liu, ZP; Mei, L; Milibari, L; Pan, JX; Ren, X; Shen, C; Sun, D; Sun, XD; Tan, ZB; Xiong, WC; Yao, LL1
Geng, Z; Liang, M; Zhang, L1
Dejakaisaya, H; Jones, NC; Kwan, P1
Hörnschemeyer, J; Kirschstein, T; Lange, F1
Holton, KF; Sarlo, GL1
Buchanan, RA; Consoli, DC; Dixit, S; Harrison, FE; May, JM; Nobis, WP; Tienda, AA; Wilcox, JM1
Baker, DH; Penkman, KEH; Smith, AK; Wade, AR1
Binder, DK; Hubbard, JA1
Bozzi, Y; Casarosa, S; Provenzano, G1
Li, W; Li, X; Quan, ZS; Wang, Q; Wu, D; Zhang, DW; Zhang, HJ1
Barbieri Caus, L; Calcagnotto, ME; Ganzella, M; Gomes de Souza, DO; Goodman, S; Junges, B; Koeller, DM; Loureiro, S; Meier, L; Umpierrez Amaral, A; Vendramin Pasquetti, M; Wajner, M; Woontner, M1
Bi, Y; Ding, L; Gao, W; Ye, M; Zhu, W1
Blümcke, I; Groemer, TW; Hackenbracht, J; Jablonski, J; Kiese, K; Kobow, K; Kornhuber, J; Wrosch, JK1
Aarão, MC; Antonio, BB; Barros, V; Bittencourt, S; de Almeida, AG; Ferrazoli, E; Janisset, NRLL; Longo, BM; Macedo, CE; Mello, LE; Miranda, MF; Mundim, M; Porcionatto, M; Rodrigues, AM; Romariz, S; Valente, MF1
Anas, ARJ; Eguchi, M; Oishi, K; Ono, K; Oya, M; Sawada, M; Suzuki, H; Yamaguchi, S1
Baroli, G; Cervelli, M; Cervetto, C; Colasanti, M; Leonetti, A; Marcoli, M; Mariottini, P; Mastrantonio, R; Maura, G; Persichini, T; Pietropaoli, S; Venturini, A1
Fighera, MR; Freitas, ML; Funck, VR; Furian, AF; Larrick, JW; Mello, FK; Oliveira, CV; Oliveira, MS; Royes, LFF1
Donovan, MJ; Gietzen, DW; Lindström, SH; Sharp, JW; Teh, PS1
Almad, A; Maragakis, NJ1
Kennedy, RT; Luna-Munguia, H; Stacey, WC; Zestos, AG1
Aldenkamp, AP; Backes, WH; Hofman, PAM; Jansen, JFA; Klomp, DW; Rouhl, RPW; Scheenen, TWJ; Tse, DHY; van Veenendaal, TM; Vlooswijk, MCG1
Danbolt, NC; Dhaher, R; Eid, T; Gruenbaum, SE; Hassel, B; Hu, QX; Hyder, F; Parent, M; Yee, SP; Zhou, Y1
Hsieh, HL; Hsieh, TY; Huang, SK; Lin, TY; Lu, CW; Wang, SJ1
Bocker, HT; Gerth, M; Heinrich, T; Hennings, JC; Hübner, CA; Isbrandt, D; Jahn, R; Jakovčevski, I; Kessels, MM; Liebmann, L; Preobraschenski, J; Qualmann, B; Seemann, E; Westermann, M1
Blake, CL; Cairelli, MJ; Fiszman, M; Kilicoglu, H; Rindflesch, TC; Zeiss, CJ1
Brandt, C; Klein, J; Löscher, W; Meller, S; Theilmann, W1
Bergner, C; Hörnschemeyer, J; Kirschstein, T; Köhling, R; Krause, BJ; Lange, F; Linnebacher, M; Mullins, CS; Porath, K; Weßlau, K1
Davis, KA; Desmond, P; Drummond, K; Glarin, R; Hariharan, H; Kwan, P; Moffat, BA; Morokoff, A; Nanga, RPR; Neal, A; O'Brien, TJ; Reddy, R; Shinohara, RT; Stein, JM1
Guo, F; Li, X; Liu, N; Ma, L; Sun, T; Yu, J; Zhang, X; Zheng, P; Zhou, R1
Furness, AM; Lunte, CE; Lunte, SM; Michealis, EK; Pal, R1
Czornyj, L; Lazarowski, A; Merelli, A1
Batra, B; Pundir, CS1
Bazan, N; Lu, Y; Pei, L; Shang, Y; Tian, Q; Wang, X; Wen, R; Yang, Y; Zhao, K; Zhu, LQ1
Battaglia, GS; Bramerio, MA; Castana, L; Colciaghi, F; Finardi, A; Fratelli, M; Locatelli, D; Lorusso, G; Marras, CE; Nobili, P1
Creevy, KE; Edwards, GL; Gagnepain, JF; Kent, M; Platt, SR1
Mishra, M; Mukherjee, S; Sharma, D; Singh, R1
Chen, CZ; Cheng, WZ; Ding, J; Fan, W; Li, X; Liang, L; Mao, LY; Peng, WF; Wang, X1
Bardelli, D; Bianchi, MG; Bussolati, O; Chiu, M1
Hasegawa, T; Horitani, Y; Komori, M; Sumita, M; Takenaka, S; Tamai, R; Tanaka, K1
Heuser, K; Szokol, K; Taubøll, E1
Alzweiri, M; Bardaweel, SK; Ishaqat, AA1
Deng, S; Ding, J; Ge, WH; Huang, C; Li, F; Li, WG; Wang, JJ; Wang, L; Xu, TL1
Carmignoto, G; Crunelli, V; Steinhäuser, C1
Andresen, L; Cantu, D; Dulla, CG; Hampton, D; Taylor-Weiner, A; Tesco, G; Walker, K1
Drummond, KJ; Kaye, AH; Liubinas, SV; Moffat, BM; Morokoff, AP; O'Brien, TJ1
DiNuzzo, M; Giove, F; Mangia, S; Maraviglia, B1
Mitsuhashi, T; Takahashi, T1
DeFranco, DB; Di Maio, R; Kanuparthi, PS; Samarasinghe, RA; Timothy Greenamyre, J1
Andresen, L; Dulla, CG; Hampton, D; Maguire, J; Morel, L; Taylor-Weiner, A; Yang, Y1
Getzinger, T; Kluger, G; Kudernatsch, M; Luna-Munguia, H; Pascher, B; Pieper, T; Potschka, H; Salvamoser, JD1
Astashev, M; Astasheva, E; Kitchigina, V1
Boets, S; Dedeurwaerdere, S; Janssens, P; Lavreysen, H; Steckler, T1
Bianchi, R; Chuang, SC; Wong, RK; Young, SR; Zhao, W1
Beauvieux, MC; Bouzier-Sore, AK; Cunnane, SC; El Hamrani, D; Gallis, JL; Naulin, J; Roy, M1
Giza, CC; Guerriero, RM; Rotenberg, A1
Aoki, CJ; Armsen, W; Bedoya, EA; Danbolt, NC; Dhamne, SC; Fischer, KD; Frederick, NM; Hameed, MQ; Miranda, C; Petr, GT; Rosenberg, PA; Rotenberg, A; Sun, Y; Wang, J; Zhou, Y1
He, J; Lei, JP; Liao, DG; Liu, F; Liu, H; Luo, K; Song, Z; Yang, L; Zhang, TY; Zhuang, K1
Coulter, DA; Dulla, CG; Ziburkus, J1
Chen, G; Foster, AC; Li, YX; Staubli, U; Sun, C; Tang, X; Wu, X; Wu, Z1
Binaschi, A; Falcicchia, C; Palma, E; Roncon, P; Simonato, M; Soukupova, M; Zucchini, S1
Kanamori, K1
Barker-Haliski, M; White, HS1
Chen, X; Guo, W; Li, S; Liu, S; Shen, K; Shu, H; Wei, Y; Yang, H; Zang, Z; Zhang, W; Zhao, B; Zheng, D; Zheng, X1
Koh, S; Piao, C; Ralay Ranaivo, H; Rusie, A; Wadhwani, N; Wainwright, MS1
Buchanan, RJ; Gjini, K; Meier, KT; Modur, P; Nadasdy, Z; Robinson, JL1
Bhandare, AM; Farnham, MM; Kapoor, K; Pilowsky, PM1
Benali, H; Bénar, CG; Benquet, P; Blanchard, S; Ivanov, A; Pélégrini-Issac, M; Saillet, S; Wendling, F1
Koshal, P; Kumar, P1
Chugani, HT; Hu, J; Juhász, C; Xuan, Y1
Han, L; Liu, X; Wang, Q1
Bonansco, C; Fuenzalida, M1
Burette, AC; Elgersma, Y; Gu, B; Han, JE; Judson, MC; King, IF; Philpot, BD; Sidorov, MS; van Woerden, GM; Wallace, ML; Weinberg, RJ; Zylka, MJ1
Cheng, J; Fan, L; Feng, S; Jia, C; Liu, Y; Lu, D; Ma, S; Su, Y; Wang, Y; Yang, S; Zhou, K1
Mazarati, A; Sankar, R1
Goel, RK; Singh, T1
Aseervatham, GS; Bose, PC; Sivasudha, T; Sundaram, S; Suryakala, U1
MacKenzie, G; Maguire, J; Moss, SJ; O'Toole, KK1
Bahi-Buisson, N; Dulac, O; Fallet-Bianco, C; Galmiche-Rolland, L; Gataullina, S; Kaminska, A; Lauer-Zillhardt, J; Ottolenghi, C; Pontoizeau, C1
Aldenkamp, AP; Backes, WH; de Louw, AJA; Edden, RAE; Hofman, PAM; IJff, DM; Jansen, JFA; Lazeron, RHC; Puts, NAJ; van Veenendaal, TM1
Castillo-Pérez, C; Custodio, V; González-Guevara, E; Hernández-Cerón, M; Martínez-Lazcano, JC; Paz, C; Rubio, C1
Adams, DR; Bhattacharya, S; Burger, PB; Chen, W; Hu, C; Kusumoto, H; Millichap, JJ; Petrovski, S; Strong, KL; Swanger, SA; Tankovic, A; Traynelis, SF; Wells, G; Yuan, H; Zhang, J1
Danbolt, NC; Dhaher, R; Eid, T; Gruenbaum, SE; Lee, TW; Zhou, Y1
Beck, H; Kelly, T1
Ding, MP; Ding, Y; Guo, Y; Shen, CH; Tang, YL; Wang, S; Zhang, YX; Zheng, Y; Zhu, JM1
Parvez, S; Raisuddin, S; Vishnoi, S1
Li, J; Sha, L; Shen, Y; Shi, X; Wang, X; Wu, L; Xu, Q1
Huang, Q; Jiang, WQ; Mei, QH; Shen, SQ; Wang, XE; Yang, Y; Yuan, C1
Bauer, B; Hartz, AM; Pekcec, A; Schlichtiger, J; Soldner, EL; Zhong, Y1
Kumar, M; Kumar, P1
Hirayama, Y; Imoto, H; Inoue, T; Maruta, Y; Nomura, S; Suehiro, E; Suzuki, M1
Kim, DS; Lee, K; Park, DK; Park, KH; Sin, DS; Yu, YH1
Auer, RN; Kherani, ZS1
Gawlak, M; Górkiewicz, T; Gorlewicz, A; Kaczmarek, L; Konopacki, FA; Wilczynski, GM1
Le Roux, PD; Monnerie, H1
Kaminski, RM; Klitgaard, H; Matagne, A; Patsalos, PN1
Fan, GG; Guo, QY; Sun, HZ; Wang, GL1
Bukovics, P; Gallyas, F; Pál, J1
Faria, LC; Fuortes, MG; Merlin, LR1
Ueda, Y; Willmore, LJ1
Aziz, MA; El Hay Ahmed, NA; Ibrahim, KM; Khadrawy, YA; Khedr, ME; Radwan, NM1
Barbieri, M; Belluzzi, O; Binaschi, A; Buzzi, A; Cifelli, P; Coffin, JD; Marzola, A; Paradiso, B; Rodi, D; Simonato, M; Zucchini, S1
Abudara, V; Giaume, C; Koulakoff, A; Rouach, N; Willecke, K1
Borbély, S; Czégé, D; Dobó, E; Mihály, A; Molnár, E; Világi, I1
Bidziński, A; Hamed, A; Lehner, M; Maciejak, P; Płaźnik, A; Skórzewska, A; Sobolewska, A; Szyndler, J; Taracha, E; Turzyńska, D; Wisłowska-Stanek, A1
Kanner, AM1
Blair, RE; DeLorenzo, RJ; Deshpande, LS; Elphick, MR; Martin, BR; Sombati, S1
Aroniadou-Anderjaska, V; Braga, MF; Figueiredo, TH; Fritsch, B; Qashu, F; Rogawski, MA1
Jiang, Q; Jiang, YW; Wu, XR1
Bar-Klein, G; Cacheaux, LP; David, Y; Friedman, A; Heinemann, U; Ivens, S; Kaufer, D; Lakhter, AJ; Shapira, M1
Cacheaux, LP; David, Y; Friedman, A; Heinemann, U; Ivens, S; Kaufer, D; Lapilover, E1
Aldouby, Y; Domb, AJ; Kubek, MJ; Veronesi, MC1
Benarroch, EE1
Cai, JQ; Guo, F; Hao, LY; Liu, R; Mao, XY; Sun, F; Tu, DY; Wang, QH; Wu, KC; Xie, N; Yu, JL1
Kardos, J; Lasztóczi, B; Nyitrai, G1
Bero, AW; Holtzman, DM; Wong, M; Zeng, LH; Zhang, B1
Hunt, RF; Scheff, SW; Smith, BN1
Dulla, CG; Huguenard, JR; Reimer, RJ; Tani, H1
Ardourel, MY; Baala, L; Briault, S; Laumonnier, F; Menuet, A; Montécot-Dubourg, C; Mortaud, S; Perche, O; Pichon, J; Richard, O; Robin, V1
Ali, F; Cavanna, AE; McCorry, D; Rickards, HE1
WAGER, RW1
Fu, M; Sun, ZH; Zuo, HC1
Eagen, KP; Ganem, B; Hess, GP; Lewis, RW; Mabry, J; Polisar, JG1
Bloss, EB; Hunter, RG1
Potschka, H1
Javed, D; Johnson-Venkatesh, EM; Sutton, MA; Terauchi, A; Toth, AB; Umemori, H1
Xie, W; Yu, Y; Zhao, Y1
de Lanerolle, NC; Lee, TS; Spencer, DD1
GOODMAN, LS; SWINYARD, EA; TOMAN, JE1
Bingaman, W; González-Martínez, JA; Najm, I; Prayson, R; Ying, Z1
Delorenzo, RJ; Deshpande, LS; Ziobro, JM1
Buckley, PT; Eberwine, JH; Porter, BE; Robinson, MB; Ross, JR1
Cano-Abad, MF; García-Navarrete, E; Herrera-Peco, I; Moro, RC; Pastor, J; Pizzo, P; Ruiz-Nuño, A; Sola, RG1
Desai, PV; Therisa, KK1
Chen, SG; Huang, HP; Lin, MX; Lin, WH1
Chang, SY; Hitti, FL; Lee, DC; Lee, KH; Leiter, JC; McIntyre, CC; Roberts, DW1
Aldana, BI; Chiu, LM; Guarneros, A; Sanchez-Tafolla, BM; Sitges, M1
Buckingham, SC; Campbell, SL; Haas, BR; Montana, V; Ogunrinu, T; Robel, S; Sontheimer, H1
Cho, GJ; Choi, WS; Jeon, BT; Jeong, EA; Kang, SS; Kim, HJ; Kim, N; Lee, DH; Roh, GS; Shin, HJ1
Simon, M; von Lehe, M1
Albrecht, J; Aschner, M; Sidoryk-Węgrzynowicz, M; Zielińska, M1
Sontheimer, H1
Houser, CR; Wyeth, MS; Zhang, N1
Gerhardt, GA; Matveeva, EA; Price, DA; Slevin, JT; Vanaman, TC; Whiteheart, SW1
Tapia, R; Vera, G1
Ashpole, NM; Brustovetsky, N; Brustovetsky, T; Cummins, TR; Engleman, EA; Hudmon, A; Song, W1
Aniksztejn, L; Cattani, AA; Mdzomba, JB; Molinari, F1
Dobolyi, A; Fiáth, R; Héja, L; Kardos, J; Kékesi, O; Nyitrai, G; Pál-Szenthe, B; Palkovits, M; Szabó, P; Ulbert, I1
Behar, K; Bumanglag, AV; Dhaher, R; Eid, T; Lee, TS1
Coulter, DA; Eid, T1
Gurkoff, GG; Lyeth, BG; Shahlaie, K1
Alkan, A; Dogan, DG; Dogan, M; Kahraman, AS; Ozcan, O; Yakinci, C1
Amrutur, B; Raghavan, M; Sikdar, SK; Srinivas, KV1
Dai, K; Hoshikawa, M; Niwa, O; Okada, M; Saito, H; Suzuki, N; Yamamura, S1
López-Pérez, SJ; Medina-Ceja, L; Morales-Villagrán, A; Sandoval-García, F1
Darnell, RB; Fak, JJ; Herre, M; Ince-Dunn, G; Jensen, KB; Mele, A; Noebels, JL; Okano, H; Okano, HJ; Park, WY; Ule, J; Yang, C; Yoo, J; Zhang, C; Zhong, R1
Bacigaluppi, M; Bari, M; Brambilla, E; Butti, E; Cambiaghi, M; Cebrian Silla, A; Centonze, D; Comi, G; D'Adamo, P; De Ceglia, R; De Chiara, V; Garcia-Verdugo, JM; Leocani, L; Maccarrone, M; Martino, G; Musella, A; Muzio, L; Quattrini, A; Rossi, S; Teneud, L1
Meldrum, BS4
Hsuchou, H; Jayaram, B; Kastin, AJ; Khan, RS; Pan, W; Wu, X1
Deng, Y; He, N; Ma, C; Wang, M; Wang, W1
Sugiura, H; Yamagata, K; Yasuda, A1
Alvarez-Linera, J; González de la Aleja, J; Hernández-Gallego, J; Hernández-Tamames, JA; Martínez-Salio, A; Mato-Abad, V; Molina, JA; Ramos, A1
De Lanerolle, NC; Devinsky, O; Najjar, S; Rogawski, MA; Vezzani, A1
Chen, N; Ge, Y; Hu, WH; Liu, C; Liu, HG; Meng, DW; Meng, FG; Yang, AC; Zhang, JG; Zhang, X1
Buckingham, SC; Robel, S1
Behar, K; Cohen, AS; Coulter, DA; Eccles, C; Ganel, R; Rafiq, A; Rothstein, JD; Sepkuty, JP1
Klisch, J; Schumacher, M; Spreer, J; Thiel, T; Ziyeh, S1
Doi, T; Mitsuyama, Y; Tokumaru, J; Tsuru, N; Ueda, Y1
Banczerowski-Pelyhe, I; Gulyás-Kovács, A; Takács, J; Tarnawa, I; Világi, I1
Blair, RE; DeLorenzo, RJ; Sombati, S; Sun, DA3
Han, S; Hu, SJ; Liu, GP; Xie, Y; Xu, JX; Yang, HJ1
Armano, S; Bacci, A; Fesce, R; Franceschetti, S; Matteoli, M; Pravettoni, E; Sancini, G; Verderio, C1
Takeda, A1
Wang, Q1
Budd, SL; Gillessen, T; Lipton, SA1
Schauwecker, PE1
Ross, B; Shic, F1
Archer, T; Beninger, RJ; Kostrzewa, RM; Palomo, T1
Aker, R; Gören, MZ; Onat, FY; Yananli, HR1
Furuta, A; Goto, Y; Iwaki, T; Kanahori, Y; Noda, M; Rothstein, JD; Suzuki, SO1
Crino, PB; Ess, KC; Gutmann, DH; Jansen, LA; Li, W; Mennerick, S; Uhlmann, EJ; Wong, M; Yamada, KA1
Friedman, LK; Kaur, J; Liu, H; Magrys, BW; Velísková, J1
Ayala, GX; Tapia, R2
Bernays, R; Blau, N; Boison, D; Imhof, HG; Rudolph, U; Wieser, HG; Yonekawa, Y1
CONSTANS, JP; PUECH, J1
LORAND, B1
DOBROWOLSKI, B1
TOWER, DB1
COLMART, C; POIRE, R; RAYEL, L; ROYER, P1
ANDREEV, AL; KHALIZEVA, EK1
Ben-Ari, Y; Holmes, GL; Khalilov, I1
Lichtman, AH; Mechoulam, R1
Azad, SC; Behl, C; Cannich, A; Casanova, E; Cascio, MG; Di Marzo, V; Eder, M; Goodenough, S; Gutiérrez, SO; Hermann, H; López-Rodriguez, ML; Lutz, B; Marsicano, G; Monory, K; Schütz, G; van der Stelt, M; Zieglgänsberger, W1
Ramírez-Munguía, N; Tapia, R; Vera, G1
MENICHETTI, E1
POND, DA; POND, MH1
Liang, LP; Patel, M1
Godukhin, OV; Kalemenev, SV; Levin, SG1
André, N; Gillardin, JM; Heulard, I; Verleye, M1
Rudenko, AIu; Svystil'nyk, VO1
de Oliveira, DL; Frizzo, ME; Horn, JF; Moriguchi, E; Rodrigues, JM; Souza, DO; Wofchuk, S1
Gibson, KM; Gupta, M; Jakobs, C; Jansen, EE; Polinsky, M; Senephansiri, H; Snead, OC1
WERNER, A1
Chen, L; Liao, WP1
Swann, JW1
Jaseja, H4
Minabe, Y; Ogino, T; Shirayama, Y; Takahashi, S1
Cavadas, C; Cristóvão, A; Ferreira, R; Grouzmann, E; Lourenço, J; Malva, JO; Oliveira, CR; Pinheiro, PS; Silva, AP; Xapelli, S1
Aldenkamp, AP; Bootsma, HP; Kessels, AG; Leenen, LA; Leonard, BE; Majoie, HJ; Roberts, GM1
Beleboni, RO; Carolino, RO; Coutinho-Netto, J; Garcia-Cairasco, N; Moyses-Neto, M; Pizzo, AB; Santos, WF; Vecchio, FD1
Hinoi, E; Takarada, T; Tsuchihashi, Y; Yoneda, Y1
Clinckers, R; Ebinger, G; Gheuens, S; Meurs, A; Michotte, Y; Smolders, I1
Dudek, FE; Shao, LR1
Sierra-Marcuño, G; Sierra-Paredes, G; Vázquez-López, A1
Chauzit, E; Feuerstein, TJ; Huppertz, HJ; Steffens, M; Zentner, J1
Azmi, H; Kang, J; Lin, J; Lou, N; Nedergaard, M; Oberheim, N; Peng, W; Takano, T; Tian, GF; Wang, X; Xu, Q; Zielke, HR1
Rogawski, MA1
Kang, J; Kang, N; Nedergaard, M; Xu, J; Xu, Q1
Changgeng, Z; Li, L; Xiaojing, W; Xiaoqin, Z; Zhengli, L1
Siva, N1
Chen, YW; Jeng, CJ; Lin, HM; Tang, CY; Wu, YS; Yeh, JH1
Beck, H; Remy, S1
Kanamatsu, T; Nakama, H; Otsuki, T; Tsukada, Y1
Hikasa, Y; Ikeda, S; Morita, T; Sato, K; Sawada, M; Shibahara, T; Shimada, A; Takahashi, M; Takeuchi, T1
Edwards, RH; Seal, RP1
Crino, PB; Gutmann, DH; Jansen, LA; Uhlmann, EJ; Wong, M1
Pan, JW; Spencer, DD; Venkatraman, T; Vives, K1
Emri, Z; Héja, L; Kardos, J; Lasztóczi, B; Nyikos, L; Simon, A; Szárics, E1
Akasu, T; Cao, R; Hasuo, H; Ooba, S; Zhang, X1
Allen, A; Daschner, J; Joseph, SA; Lynd-Balta, E; O'Banion, MK; Padowski, J; Rappold, PM1
Bozzao, L; Carní, M; Colonnese, C; Di Bonaventura, C; Garreffa, G; Giallonardo, AT; Giove, F; Macrì, MA; Maraviglia, B; Pantano, P; Peca, S; Prencipe, M; Vaudano, AE1
Raiteri, M1
Orme-Johnson, D1
Kapaki, E; Limpitaki, G; Paraskevas, GP; Petropoulou, O; Triantafyllou, NI; Vassilopoulos, D1
Gutiérrez, R; Heinemann, U1
Ben-Ari, Y1
Ben-Ari, Y; Bihi, RI; Crépel, V; Epsztein, J; Jorquera, I; Milh, M; Represa, A1
Di Luca, M; Gardoni, F1
DeLorenzo, RJ; Deshpande, LS; Sun, DA1
Binder, DK; Steinhäuser, C1
Blaudzun, H; Dodt, HU; During, M; Eder, M; Egertová, M; Ekker, M; Elphick, MR; Goebbels, S; Jacob, W; Kelsch, W; Klugmann, M; Long, J; Lutz, B; Mackie, K; Marsch, R; Marsicano, G; Massa, F; Monory, K; Nave, KA; Rubenstein, JL; Westenbroek, R; Wölfel, B; Wotjak, CT; Zieglgänsberger, W1
Carmignoto, G; Fellin, T; Gobbo, S; Gomez-Gonzalo, M; Haydon, PG1
Blair, RE; Carter, DS; DeLorenzo, RJ; Deshpande, LS; Haider, SN; Sombati, S1
Bjørnsen, LP; Danbolt, NC; de Lanerolle, NC; Eid, T; Holmseth, S; Spencer, DD1
Patrylo, PR; Willingham, A1
Le, JT; Lee, CL; Swann, JW1
Fellin, T; Halassa, MM; Haydon, PG1
Avallone, J; Friedman, LK; Gashi, E; Webster, T1
Bai, ZT; Chai, ZF; Ji, YH; Liu, T; Pang, XY; Zhang, XY1
Frahm, C; Gorter, JA; Heinemann, U; Lopes da Silva, FH; Metzger, R; Tolner, EA; Witte, OW1
Henshall, DC1
Bianchi, R; Chuang, SC; Wang, M; Wong, RK; Zhao, W1
Bough, KJ; Dingledine, R; Hall, RA; Hassel, B; Paquet, M; Paré, JF; Smith, Y1
Becker, AJ; Flor, PJ; Gueler, N; Pitsch, J; Schoch, S; van der Putten, H1
Barker, GJ; Duncan, JS; McLean, MA; Simister, RJ1
Doi, T; Nagatomo, K; Nakajima, A; Ueda, Y; Willmore, LJ1
Jain, R; Saurav, S; Sikdar, SK; Srinivas, KV1
Auberson, M; Blanz, J; Hübner, CA; Jentsch, TJ; Maier, H; Muenscher, A; Schweizer, M1
Carolino, RO; Coutinho-Netto, J; Cunha, AO; Dos Santos, WF; Mortari, MR1
Compte, A; Descalzo, VF; Figueroa, NA; Gallego, R; Reig, R; Sanchez-Vives, MV1
Bidziński, A; Hamed, A; Lehner, M; Maciejak, P; Płaźnik, A; Skórzewska, A; Sobolewska, A; Szyndler, J; Taracha, E; Turzyńska, D; Walkowiak, J; Wisłowska, A1
Carvalho, AL; Duarte, CB; Ferreira, JS; Gomes, AR; Lerma, J; Paternain, AV1
Khan, R; Krishnakumar, A; Paulose, CS1
Bonner, CT; Bonner, HP; Concannon, CG; Engel, T; Henshall, DC; Kuroki, K; Prehn, JH; Tuffy, LP; Ward, MW; Woods, I1
Chapman, J; Maggio, N; Segal, M; Shavit, E1
Aroniadou-Anderjaska, V; Braga, MF; Fritsch, B; Qashu, F1
Jesse, CR; Nogueira, CW; Rocha, JB; Savegnago, L1
Mulle, C; Vincent, P1
Gundersen, V1
Chu, J; Ma, Y; Zhang, B; Zhang, J1
Kühne, GE; Wolf, G1
Walker, JE1
Craig, CR1
Merlin, LR; Taylor, GW; Wong, RK1
Brusa, R; Feldmeyer, D; Gass, P; Koh, DS; Seeburg, PH; Sprengel, R; Zimmermann, F1
Bockaert, J; Fagni, L; Lafon-Cazal, M; Lerner-Natoli, M; Manzoni, O; Rondouin, G1
Behar, KL; Mattson, RH; Petroff, OA; Rothman, DL1
Gerfin-Moser, A; Grogg, F; Rietschin, L; Streit, P; Thompson, SM1
Hyvönen, M; Lahtinen, H; Miettinen, R; Riekkinen, PJ; Sirviö, J; Ylinen, A1
Flavin, HJ; Seyfried, TN1
Baumeister, FA; Egger, J; Gsell, W; Shin, YS1
Tamura, M; Yanagida, M1
Lasley, SM; Yan, QS1
Castrén, E; Lahtinen, H; Miettinen, R; Paljärvi, L; Riekkinen, PJ; Ylinen, A1
Chapman, AG; Meldrum, BS; Millan, MH1
Halonen, T; Kälviäinen, R; Pitkänen, A; Riekkinen, PJ1
Hamberger, A; van Gelder, NM1
Cornell-Bell, AH; Lee, SH; Magge, S; Sontheimer, H; Spencer, DD1
Haapalinna, A; Halonen, T; Riekkinen, P; Valtonen, P1
Attwell, PJ; Bradford, HF; Croucher, MJ; Jane, DE; Kaura, S; Sigala, G; Watkins, JC1
el-Alazounni, H; Griebel, R; Kalra, J; Kanthan, R; Miyashita, H; Shuaib, A1
Acosta, GB; Wikinski, SI1
Bachelard, H; Morris, P; Taylor, A; Thatcher, N1
DuPont, BR; Leach, RJ; Lewis, TB; Michaelis, EK; Wood, S1
Bradford, HF1
Ishihara, K; Ishii, A; Kanda, T; Kurokawa, M; Kuwana, Y; Nakamura, J; Sasa, M; Serikawa, T; Tamura, S; Yamada, J1
Köhling, R; Lücke, A; Speckmann, EJ1
Attwell, D; Billups, B; Hamann, M; Rossi, D; Sarantis, M; Takahashi, M1
Dudek, FE; Spitz, M1
Hori, S; Ichihara, N; Iwama, H; Kawashima, N; Kikuchi, T; Manabe, T; Nishikawa, T; Okuyama, S; Takahashi, K; Takimoto, M; Tanaka, K; Wada, K; Watanabe, M; Watase, K; Yamada, K1
Fischer, KM1
Janzen, J; Peghini, P; Stoffel, W1
Alonso, A; Dickson, CT1
Becker, A; Krug, M; Schröder, H1
Claudio, OI; Cordero, ML; Ortiz, JG; Santiago, G1
Jones, RS1
Chapman, AG; Elwes, RD; Meldrum, BS; Millan, MH; Polkey, CE1
Lee, FS; Lewis, SM; Seyfried, TN; Todorova, M; Ueda, T1
Bittigau, P; Ikonomidou, C1
Kempski, OS; Lowitzsch, K; Stover, JF1
Abdul-Ghani, AS; Attwell, PJ; Bradford, HF; Croucher, MJ; Koumentaki, A1
Akimitsu, T; Arita, K; Hanaya, R; Iida, K; Ishihara, K; Kurisu, K; Sasa, M; Serikawa, T; Ujihara, H1
Bashkatova, VG; Rayevsky, KS1
March, PA1
Bowyer, JF; Peterson, SL; Rountree, RL; Tor-Agbidye, J; Wang, GJ1
Curran, T; Morgan, JI; Vendrell, M1
Jefferys, JG; Traub, RD1
Scheyer, RD1
Honkaniemi, J; Sharp, FR1
Ben-Ari, Y; Bernard, A; Charton, G; Dessi, F; Ferhat, L; Khrestchatisky, M; Represa, A1
Casebeer, D; Faingold, C1
French, SJ; Horner, CH; Humby, T; Rattray, M; Sofroniew, MV1
Conti, M; De Luigi, A; De Simoni, MG; Marchesi, F; Moneta, D; Ravizza, T; Vezzani, A1
Ferraro, G; La Grutta, V; Montalbano, ME1
Beani, L; Bianchi, C; Borea, PA; Bregola, G; Gessi, S; Regoli, D; Simonato, M; Varani, K1
Donnelly, S; Loscher, C; Lynch, MA; Mills, KH1
Bianchi, R; Merlin, LR; Taylor, GW; Wong, RK1
Akbar, MT; Chapman, AG; Meldrum, BS1
Li, X; Xiao, Y1
Standley, CA1
Altemus, KL; Ariano, MA; Cepeda, C; Crawford, CA; Cromwell, HC; Levine, MS; Li, Z; Mathern, GW; Nansen, EA; Peacock, WJ; Sibley, DR1
Angelatou, F; Ekonomou, A1
Krishnamoorthy, ES; Trimble, MR1
da Silva Aresta Belo, AI; Ghijsen, WE; Lopez da Silva, FH; Zuiderwijk, M1
Thio, LL; Wong, M; Yamada, KA1
Chapman, AG1
Keele, NB; Neugebauer, V; Shinnick-Gallagher, P; Zinebi, F1
Doyle, WK; Freund, TF; Gulácsi, A; Lai, Y; Mody, I; Pacia, S; Sík, A1
da Silveira Perla, A; de Faria Maraschin, J; Lara, DR; Onofre Souza, D; Schmidt, AP1
Hopkins, KJ; Schmued, LC; Wang, G1
Lukasiuk, K; Pitkänen, A1
Chugani, DC; Chugani, HT; Juhász, C; Moore, GJ; Muzik, O; Pfund, Z; Seraji-Bozorgzad, N; Wilds, IB1
Dacanal, J; de Mello, CF; de Souza, DO; Emanuelli, T; Prauchner, CA; Reis, EC; Zeni, A1
Berchanski, A; Elazar, Z1
Arroyo, S; Casanovas-Aguilar, C; Danscher, G; Franco-Pons, N; Pérez-Clausell, J; Rumià, J1
Dammerman, RS; Kriegstein, AR1
Barker, GJ; Duncan, JS; McLean, MA; Woermann, FG1
Claudio, OI; Ferchmin, P; Moshé, SL; Ortiz, JG; Sperber, EF; Velísek, L1
DeLorenzo, RJ; Limbrick, DD; Pal, S; Rafiq, A1
Binaschi, A; Bregola, G; Gemignani, A; Marti, M; Simonato, M1
Czuczwar, SJ; Deckers, CL; Hekster, YA; Keyser, A; Kubova, H; Meinardi, H; Patsalos, PN; Renier, WO; Van Rijn, CM1
Gutiérrez, R1
Peña, F; Tapia, R1
Doi, T; Mitsuyama, Y; Tokumaru, J; Ueda, Y; Willmore, LJ2
Senra-Vidal, A; Sierra-Marcuño, G; Sierra-Paredes, G1
Barker, GJ; Bartlett, PA; Duncan, JS; McLean, MA; Woermann, FG1
Doi, T; Kamada, H; Mitsuyama, Y; Nakajima, A; Ohya-Nishiguchi, H; Tokumaru, J; Ueda, Y; Willmore, LJ; Yokoyama, H1
Gabel, LA; LoTurco, JJ1
Flink, R; Hillered, L; Kihlström, L; Lindquist, C; Nie, JX; Olsson, Y; Ronne Engström, E; Silander, HC1
D'Hooge, R; De Deyn, PP; Engelborghs, S1
Bondada, S; Culmsee, C; Mattson, MP1
Duan, W; Guo, Z; Lee, J; Mattson, MP1
Ebner, A; Gorji, A; Höhling, JM; Köhling, R; Oppel, F; Scheller, D; Speckmann, EJ; Straub, H; Tegtmeier, F; Tuxhorn, I; Werner Panneck, H; Wolf, P1
Brodie, MJ; Kwan, P; Sills, GJ1
DeFelipe, J; Gómez-Utrero, E; González-Albo, MC; Sánchez, A; Sola, RG1
Autere, AM; Kaila, K; Lahtinen, H; Lauri, SE; Paalasmaa, P1
Madamba, SG; Siggins, GR; Tallent, MK1
Avakian, GN; Gusev, EI; Kudrin, VS; Nesterova, SI; Raevskiĭ, KS1
Burgos, JS; Frizzo, ME; Lara, DR; Ramírez, G; Schmidt, AP; Souza, DO1
Araújo, DA; Beirão, PS; Cruz, JS; Mafra, RA1
DeLorenzo, RJ; Limbrick, D; Pal, S; Rafiq, A; Sun, D1
DeLorenzo, RJ; Sombati, S; Sun, DA1
Cunningham, MO; Evans, DI; Jones, RS; Woodhall, G1
Fedele, E; Marchi, M; Raiteri, M1
Buckby, LE; Lacey, MG1
Kumar, P; Raju, TR1
Camón, L; de Vera, N; Martínez, E1
Brooks-Kayal, AR; Lynch, DR; Raol, YH1
Czuczwar, SJ1
Aronica, E; De Graan, PN; Ghijsen, WE; Gorter, JA; Lopes Da Silva, FH; Proper, EA; Van Vliet, EA1
Garg, BP; Kubek, MJ1
Hilgenberg, LG; Ho, KD; Lee, D; O'Dowd, DK; Smith, MA1
Blüml, S; Moreno-Torres, A; Nguy, CH; Ross, BD; Shic, F1
Borrelli, E; Bozzi, Y1
Dudek, FE; Smith, BN1
Söderpalm, B1
He, RR; Wang, H; Wang, ZA1
Avshalumov, MV; Rice, ME1
Holmes, GL; Stafstrom, CE; Tandon, P; Yang, Y1
Errante, LD; Kim, JH; Petroff, OA; Rothman, DL; Spencer, DD1
Cole, AE; Fisher, RS1
Kulkarni, SK; Mehta, AK; Ticku, MK1
Eguchi, T; Hirabayashi, H; Morimoto, T; Nakase, H; Sakaki, T; Tada, T2
Carter, RE; Coyle, JT; Meyerhoff, JL; Slusher, BS; Yourick, DL1
Hertz, L; Petersen, SB; Schousboe, A; Sonnewald, U; Westergaard, N; Yu, AC1
Flavin, HJ; Seyfried, TN; Wieraszko, A1
Avoli, M; Perreault, P1
Higashi, H; Nishi, S; Tanaka, E1
Haberly, LB; Hoffman, WH1
Isokawa, M; Mello, LE1
Craig, CR; Fleming, WW; Gould, EM; Taylor, DA1
Bettucci, D; Cantello, R; Gianelli, M; Mutani, R1
Chapman, A; Meldrum, B1
Gunawan, S; Treiman, DM; Walton, NY1
van Gelder, NM2
Hiramatsu, M; Janjua, NA; Mori, A1
Hattori, Y; Hayashi, Y; Hori, Y; Moriwaki, A1
Porter, RJ1
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Dempster, DW; Sloviter, RS1
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Ingvar, M; Siesjö, BK; Wieloch, T1
Diemer, NH; Johansen, FF; Jørgensen, MB1
Crawford, IL1
Ben-Ari, Y; Schwarcz, R1
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Connick, JH; English, M; Hastings, MH; Stone, TW; Winn, P1
Meldrum, BS; Ottersen, OP; Storm-Mathisen, J; Swan, JH1
Keilhoff, G; Wolf, G1
Kumashiro, H; Mori, N; Sato, T1

Reviews

106 review(s) available for glutamic acid and Aura

ArticleYear
Role of glutamate excitotoxicity and glutamate transporter EAAT2 in epilepsy: Opportunities for novel therapeutics development.
    Biochemical pharmacology, 2021, Volume: 193

    Topics: Animals; Anticonvulsants; Epilepsy; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glutamic Acid; Humans

2021
The role of excitatory amino acid transporter 2 (EAAT2) in epilepsy and other neurological disorders.
    Metabolic brain disease, 2023, Volume: 38, Issue:1

    Topics: Animals; Biological Transport; Epilepsy; Excitatory Amino Acid Transporter 2; Glutamic Acid; Humans; Mammals; Schizophrenia

2023
Overview Article Astrocytes as Initiators of Epilepsy.
    Neurochemical research, 2023, Volume: 48, Issue:4

    Topics: Astrocytes; Brain; Epilepsy; Glutamic Acid; Humans; Synaptic Transmission

2023
Astrocyte-neuron circuits in epilepsy.
    Neurobiology of disease, 2023, Volume: 179

    Topics: Adenosine; Astrocytes; Epilepsy; Glutamic Acid; Humans; Neurons

2023
Understanding Lamotrigine's Role in the CNS and Possible Future Evolution.
    International journal of molecular sciences, 2023, Mar-23, Volume: 24, Issue:7

    Topics: Anticonvulsants; Central Nervous System; Depressive Disorder, Major; Epilepsy; Glutamic Acid; Humans; Ion Channels; Lamotrigine; Triazines

2023
Sex Hormones, Neurosteroids, and Glutamatergic Neurotransmission: A Review of the Literature.
    Neuroendocrinology, 2023, Volume: 113, Issue:9

    Topics: Chronic Pain; Epilepsy; Estrogens; Glutamic Acid; Gonadal Steroid Hormones; Humans; Neurosteroids

2023
Optogenetic and chemogenetic therapies for epilepsy.
    Neuropharmacology, 2020, 05-15, Volume: 168

    Topics: Animals; Anticonvulsants; Brain; Drug Resistant Epilepsy; Epilepsy; Genetic Therapy; Glutamic Acid; Humans; Ion Channel Gating; Optogenetics

2020
Role of cerebral glutamate in post-stroke epileptogenesis.
    NeuroImage. Clinical, 2019, Volume: 24

    Topics: Animals; Brain; Epilepsy; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Stroke

2019
Ionotropic Glutamate Receptors in Epilepsy: A Review Focusing on AMPA and NMDA Receptors.
    Biomolecules, 2020, 03-18, Volume: 10, Issue:3

    Topics: Animals; Anticonvulsants; Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Receptors, Ionotropic Glutamate

2020
A Review of Molecular Imaging of Glutamate Receptors.
    Molecules (Basel, Switzerland), 2020, Oct-16, Volume: 25, Issue:20

    Topics: Animals; Brain; Epilepsy; Glutamic Acid; Humans; Molecular Imaging; Neurodegenerative Diseases; Receptors, Glutamate; Schizophrenia; Stroke; Tomography, Emission-Computed, Single-Photon

2020
Revisiting the role of neurotransmitters in epilepsy: An updated review.
    Life sciences, 2021, Jan-15, Volume: 265

    Topics: Acetylcholine; Animals; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Mutation; Neurotransmitter Agents; Nitric Oxide; Receptors, Neurotransmitter

2021
Neonatal Hypoglycemia and Brain Vulnerability.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Brain; Brain Injuries; Cell Death; Epilepsy; Glucose; Glutamic Acid; Homeostasis; Humans; Hypoglycemia; Infant, Newborn; Infant, Newborn, Diseases; Neurons; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Receptors, Glutamate; Risk Factors; Zinc

2021
Advances in the Development of Biomarkers for Poststroke Epilepsy.
    BioMed research international, 2021, Volume: 2021

    Topics: Biomarkers; Epilepsy; Glutamic Acid; Humans; Interleukin-6; S100 Calcium Binding Protein beta Subunit; Stroke; Tumor Necrosis Factor-alpha

2021
Astrocyte and glutamate involvement in the pathogenesis of epilepsy in Alzheimer's disease.
    Epilepsia, 2021, Volume: 62, Issue:7

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Astrocytes; Encephalitis; Epilepsy; Glutamic Acid; Humans; Middle Aged

2021
Glutamatergic Mechanisms in Glioblastoma and Tumor-Associated Epilepsy.
    Cells, 2021, 05-17, Volume: 10, Issue:5

    Topics: Animals; Anticonvulsants; Antineoplastic Agents; Brain; Brain Neoplasms; Brain Waves; Disease Progression; Epilepsy; Excitatory Amino Acid Antagonists; Glioblastoma; Glutamic Acid; Humans; Receptors, Ionotropic Glutamate; Receptors, Metabotropic Glutamate; Signal Transduction

2021
Brain concentrations of glutamate and GABA in human epilepsy: A review.
    Seizure, 2021, Volume: 91

    Topics: Brain; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans

2021
Neurobiological bases of autism-epilepsy comorbidity: a focus on excitation/inhibition imbalance.
    The European journal of neuroscience, 2018, Volume: 47, Issue:6

    Topics: Animals; Autism Spectrum Disorder; Comorbidity; Cortical Excitability; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Neural Inhibition

2018
A stocked toolbox for understanding the role of astrocytes in disease.
    Nature reviews. Neurology, 2018, Volume: 14, Issue:6

    Topics: Animals; Astrocytes; Calcium; Epilepsy; Glutamic Acid; Humans; Induced Pluripotent Stem Cells; Laser Scanning Cytometry; Microscopy, Fluorescence, Multiphoton; Neurodegenerative Diseases; Neurodevelopmental Disorders; Optogenetics

2018
Use and Future Prospects of in Vivo Microdialysis for Epilepsy Studies.
    ACS chemical neuroscience, 2019, 04-17, Volume: 10, Issue:4

    Topics: Animals; Brain; Chromatography, Liquid; Electrophoresis, Capillary; Epilepsy; Forecasting; gamma-Aminobutyric Acid; Glutamic Acid; Histamine; Humans; Microdialysis; Neurotransmitter Agents; Spectrometry, Fluorescence

2019
Erythropoietin: a neuroprotective agent in cerebral hypoxia, neurodegeneration, and epilepsy.
    Current pharmaceutical design, 2013, Volume: 19, Issue:38

    Topics: Animals; Epilepsy; Erythropoietin; Glutamic Acid; Humans; Hypoxia-Inducible Factor 1; Hypoxia, Brain; Neurodegenerative Diseases; Neuroprotective Agents; Receptors, Erythropoietin

2013
Changes in the expression of the glutamate transporter EAAT3/EAAC1 in health and disease.
    Cellular and molecular life sciences : CMLS, 2014, Volume: 71, Issue:11

    Topics: Animals; Biological Transport; Central Nervous System; Epilepsy; Excitatory Amino Acid Transporter 3; Gene Expression Regulation; Glutamic Acid; Homeostasis; Humans; Hypoxia; Mice; Multiple Sclerosis; Oxidative Stress; Schizophrenia; Signal Transduction

2014
The role of glial cells in epilepsy.
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2014, Jan-14, Volume: 134, Issue:1

    Topics: Aquaporin 4; Astrocytes; Calcium Signaling; Epilepsy; Gap Junctions; Glutamic Acid; Humans; Neuroglia; Potassium Channels, Inwardly Rectifying; Synaptic Transmission; Water-Electrolyte Balance

2014
D-Serine in neurobiology: CNS neurotransmission and neuromodulation.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2014, Volume: 41, Issue:2

    Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Central Nervous System; Epilepsy; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Mental Disorders; Neurodegenerative Diseases; Neuronal Plasticity; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate; Serine; Synaptic Transmission

2014
Novel astrocyte targets: new avenues for the therapeutic treatment of epilepsy.
    The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 2015, Volume: 21, Issue:1

    Topics: Animals; Aquaporins; Astrocytes; Brain; Calcium Signaling; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Gap Junctions; Glutamic Acid; Humans; Potassium Channels

2015
Tumour associated epilepsy and glutamate excitotoxicity in patients with gliomas.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:6

    Topics: Animals; Brain Neoplasms; Epilepsy; Glioma; Glutamic Acid; Humans; Quality of Life; Synaptic Transmission

2014
Physiological bases of the K+ and the glutamate/GABA hypotheses of epilepsy.
    Epilepsy research, 2014, Volume: 108, Issue:6

    Topics: Animals; Astrocytes; Brain; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Glycogen; Humans; Models, Neurological; Neurons; Potassium

2014
[Neocortical histogenesis and intractable epilepsy].
    No to hattatsu = Brain and development, 2014, Volume: 46, Issue:3

    Topics: Animals; Cell Differentiation; Cell Division; Cell Movement; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Neocortex; Neuroglia; Neurons; Neurotransmitter Agents; Synapses; Synaptic Transmission

2014
In the grey zone between epilepsy and schizophrenia: alterations in group II metabotropic glutamate receptors.
    Acta neurologica Belgica, 2015, Volume: 115, Issue:3

    Topics: Animals; Brain; Epilepsy; Glutamic Acid; Humans; Receptors, Metabotropic Glutamate; Schizophrenia

2015
Glutamate and GABA imbalance following traumatic brain injury.
    Current neurology and neuroscience reports, 2015, Volume: 15, Issue:5

    Topics: Animals; Brain Injuries; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Homeostasis; Humans; Receptors, GABA; Receptors, Glutamate

2015
From Molecular Circuit Dysfunction to Disease: Case Studies in Epilepsy, Traumatic Brain Injury, and Alzheimer's Disease.
    The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 2016, Volume: 22, Issue:3

    Topics: Alzheimer Disease; Animals; Brain; Brain Injuries, Traumatic; Cerebral Cortex; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; Ion Channels; Neural Pathways; Neurons; tau Proteins; Thalamus; TOR Serine-Threonine Kinases

2016
Glutamatergic Mechanisms Associated with Seizures and Epilepsy.
    Cold Spring Harbor perspectives in medicine, 2015, Jun-22, Volume: 5, Issue:8

    Topics: Anticonvulsants; Epilepsy; Female; Glutamic Acid; Humans; Male; Receptors, Glutamate; Reference Values; Seizures; Signal Transduction; Synaptic Transmission

2015
Plasticity of Hippocampal Excitatory-Inhibitory Balance: Missing the Synaptic Control in the Epileptic Brain.
    Neural plasticity, 2016, Volume: 2016

    Topics: Animals; Astrocytes; Brain; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; Neuronal Plasticity; Synapses; Synaptic Transmission

2016
Common Mechanisms Underlying Epileptogenesis and the Comorbidities of Epilepsy.
    Cold Spring Harbor perspectives in medicine, 2016, 07-01, Volume: 6, Issue:7

    Topics: Animals; Brain; Comorbidity; Depression; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Hypothalamo-Hypophyseal System; Inflammation; Magnetic Resonance Imaging; Neurotransmitter Agents; Quality of Life; Serotonin

2016
The Glutamate-Glutamine Cycle in Epilepsy.
    Advances in neurobiology, 2016, Volume: 13

    Topics: Astrocytes; Epilepsy; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Humans

2016
Glutamate Excitotoxicity and Oxidative Stress in Epilepsy: Modulatory Role of Melatonin.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2016, Volume: 35, Issue:4

    Topics: Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Melatonin; Neurotoxins; Oxidative Stress; Reactive Oxygen Species

2016
Benefit of combination therapy in epilepsy: a review of the preclinical evidence with levetiracetam.
    Epilepsia, 2009, Volume: 50, Issue:3

    Topics: Animals; Anticonvulsants; Brain; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Interactions; Drug Therapy, Combination; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Levetiracetam; Membrane Glycoproteins; Nerve Tissue Proteins; Piracetam

2009
[Progress in the study of the chemical synapse in glioma-associated epileptogenesis].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2008, Aug-18, Volume: 40, Issue:4

    Topics: Brain Neoplasms; Epilepsy; Glioma; Glutamic Acid; Humans; Neurotransmitter Agents; Neurotransmitter Transport Proteins; Synapses

2008
Posttraumatic epilepsy: hemorrhage, free radicals and the molecular regulation of glutamate.
    Neurochemical research, 2009, Volume: 34, Issue:4

    Topics: Animals; Antioxidants; Brain Injuries; Disease Models, Animal; Epilepsy; Free Radicals; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Intracranial Hemorrhages; Neurons; Neuropil; Nitric Oxide; Oxidation-Reduction

2009
Depression and epilepsy: do glucocorticoids and glutamate explain their relationship?
    Current neurology and neuroscience reports, 2009, Volume: 9, Issue:4

    Topics: Animals; Comorbidity; Depressive Disorder; Epilepsy; Glucocorticoids; Glutamic Acid; Humans; Hypothalamo-Hypophyseal System; Pituitary-Adrenal System; Quality of Life; Risk Factors; Suicide

2009
[Advances in studies on molecular mechanisms underlying epileptogenesis].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2009, Volume: 47, Issue:5

    Topics: Epilepsy; Glutamic Acid; Humans; Ion Channels; Receptors, GABA-A

2009
[Autism, genetics and synaptic function alterations].
    Pathologie-biologie, 2010, Volume: 58, Issue:5

    Topics: Asperger Syndrome; Astrocytes; Autistic Disorder; Carrier Proteins; Cell Adhesion Molecules, Neuronal; Child; Child Development Disorders, Pervasive; Comorbidity; Epilepsy; Glutamic Acid; Humans; Incidence; Intellectual Disability; Membrane Proteins; Receptors, Glutamate; Synaptic Transmission

2010
Behavioral and cognitive effects of anti-epileptic drugs.
    Discovery medicine, 2010, Volume: 9, Issue:45

    Topics: Amines; Anticonvulsants; Antidepressive Agents; Behavior; Cognition; Cognition Disorders; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Lamotrigine; Neurotransmitter Agents; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Triazines; Vigabatrin

2010
Hippocampal kainate receptors.
    Vitamins and hormones, 2010, Volume: 82

    Topics: Animals; Epilepsy; Glutamic Acid; Hippocampus; Humans; Mental Disorders; Neuronal Plasticity; Rats; Receptors, Kainic Acid

2010
Modulating P-glycoprotein regulation: future perspectives for pharmacoresistant epilepsies?
    Epilepsia, 2010, Volume: 51, Issue:8

    Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Drug Resistance; Epilepsy; Glutamic Acid; Humans; Models, Biological; Signal Transduction

2010
Astrocytes and epilepsy.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2010, Volume: 7, Issue:4

    Topics: Animals; Astrocytes; Brain; Calcium; Epilepsy; Gene Expression; Glial Fibrillary Acidic Protein; Glutamic Acid; Humans; Models, Biological

2010
Roles of glutamine in neurotransmission.
    Neuron glia biology, 2010, Volume: 6, Issue:4

    Topics: Animals; Central Nervous System; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Models, Biological; Neuroglia; Neurons; Neurotoxicity Syndromes; Neurotransmitter Agents; Synaptic Transmission

2010
Roles of glutamine synthetase inhibition in epilepsy.
    Neurochemical research, 2012, Volume: 37, Issue:11

    Topics: Ammonia; Animals; Epilepsy; gamma-Aminobutyric Acid; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Humans

2012
Astrocytic regulation of glutamate homeostasis in epilepsy.
    Glia, 2012, Volume: 60, Issue:8

    Topics: Animals; Astrocytes; Epilepsy; Glutamic Acid; Homeostasis; Humans

2012
Neurotransmission in epilepsy.
    Epilepsia, 1995, Volume: 36 Suppl 1

    Topics: Animals; Epilepsy; GABAergic Neurons; Glutamic Acid; Humans; Neural Inhibition; Synaptic Transmission

1995
Glia and epilepsy: excitability and inflammation.
    Trends in neurosciences, 2013, Volume: 36, Issue:3

    Topics: Action Potentials; Animals; Anticonvulsants; Blood-Brain Barrier; Body Water; Calcium Signaling; Cytokines; Drug Resistance; Encephalitis; Epilepsy; Extracellular Space; Gliosis; Glutamic Acid; Humans; Inflammation Mediators; Ion Channels; Microcirculation; Models, Neurological; Nerve Tissue Proteins; Neuroglia; Neurons; Potassium

2013
Glutamate and tumor-associated epilepsy: glial cell dysfunction in the peritumoral environment.
    Neurochemistry international, 2013, Volume: 63, Issue:7

    Topics: Blood-Brain Barrier; Epilepsy; Glutamic Acid; Homeostasis; Humans; Neoplasms; Neuroglia; Potassium

2013
Manganese action in brain function.
    Brain research. Brain research reviews, 2003, Volume: 41, Issue:1

    Topics: Animals; Basal Ganglia Diseases; Brain; Epilepsy; Glutamic Acid; Humans; Manganese; Manganese Poisoning; Metalloproteins; Presynaptic Terminals; Synaptic Transmission

2003
[The roles of estrogen and progestin in epileptogenesis and their mechanisms of action].
    Sheng li ke xue jin zhan [Progress in physiology], 2000, Volume: 31, Issue:3

    Topics: Animals; Cerebral Cortex; Epilepsy; Estrogens; Genes, Immediate-Early; Glutamic Acid; Hippocampus; Neurotransmitter Agents; Progestins; Rats; Receptors, Estrogen; Receptors, Progesterone

2000
Excitatory amino acid neurotoxicity.
    Advances in experimental medicine and biology, 2002, Volume: 513

    Topics: Animals; Aspartic Acid; Brain; Brain Injuries; Brain Ischemia; Calcium; Epilepsy; Glutamic Acid; Humans; Mitochondria; Nervous System Diseases; Neurodegenerative Diseases; Reactive Nitrogen Species; Reactive Oxygen Species; Receptors, Glutamate; Signal Transduction

2002
Brain sites of movement disorder: genetic and environmental agents in neurodevelopmental perturbations.
    Neurotoxicity research, 2003, Volume: 5, Issue:1-2

    Topics: Ataxia; Attention Deficit Disorder with Hyperactivity; Environmental Pollutants; Epilepsy; Glutamic Acid; Humans; Infant, Newborn; Iron; Mercury; Movement Disorders; Multiple Sclerosis; Mutagens; Neostriatum; Nerve Growth Factors; Receptors, Dopamine

2003
[Modern views on the correlation of brain metabolites in pathogenesis of epilepsy in children].
    Likars'ka sprava, 2004, Issue:2

    Topics: Biogenic Amines; Brain; Child; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Humans

2004
The impact of seizures on developing hippocampal networks.
    Progress in brain research, 2005, Volume: 147

    Topics: Animals; Animals, Newborn; Epilepsy; Glutamic Acid; Hippocampus; Humans; Learning Disabilities; Recurrence; Synapses

2005
Glutamate transporters as drug targets.
    Current drug targets. CNS and neurological disorders, 2005, Volume: 4, Issue:2

    Topics: Alzheimer Disease; Amino Acid Transport System X-AG; Amyotrophic Lateral Sclerosis; Animals; Biological Transport; Brain Ischemia; Drug Design; Epilepsy; Glutamic Acid; Humans; Membrane Transport Proteins; Schizophrenia; Transport Vesicles

2005
Molecular and cellular mechanisms of pharmacoresistance in epilepsy.
    Brain : a journal of neurology, 2006, Volume: 129, Issue:Pt 1

    Topics: Animals; Anticonvulsants; Biological Transport; Blood-Brain Barrier; Brain; Drug Resistance; Epilepsy; Forecasting; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Ion Channels; Models, Animal; Multidrug Resistance-Associated Proteins

2006
Functional implications of neurotransmitter co-release: glutamate and GABA share the load.
    Current opinion in pharmacology, 2006, Volume: 6, Issue:1

    Topics: Acetylcholine; Animals; Brain Stem; Dentate Gyrus; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Neuronal Plasticity; Neurons; Neurotransmitter Agents; Olfactory Bulb; Synaptic Transmission

2006
Functional pharmacology in human brain.
    Pharmacological reviews, 2006, Volume: 58, Issue:2

    Topics: Acetylcholine; Alzheimer Disease; Brain; Brain Ischemia; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Neurons; Norepinephrine; Receptors, Adrenergic; Receptors, Cholinergic; Receptors, GABA; Receptors, Glutamate; Synaptic Transmission

2006
Co-existence of GABA and Glu in the hippocampal granule cells: implications for epilepsy.
    Current topics in medicinal chemistry, 2006, Volume: 6, Issue:10

    Topics: Animals; Cytoplasmic Granules; Electric Stimulation; Epilepsy; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; Magnetics

2006
Basic developmental rules and their implications for epilepsy in the immature brain.
    Epileptic disorders : international epilepsy journal with videotape, 2006, Volume: 8, Issue:2

    Topics: Animals; Brain; Cell Movement; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Neurons; Neurotransmitter Agents; Paracrine Communication; Synapses

2006
New targets for pharmacological intervention in the glutamatergic synapse.
    European journal of pharmacology, 2006, Sep-01, Volume: 545, Issue:1

    Topics: Alzheimer Disease; Animals; Epilepsy; Glutamic Acid; Humans; Huntington Disease; Ischemia; Parkinson Disease; Protein Kinases; Receptors, N-Methyl-D-Aspartate; Synapses

2006
Erratum to "Cellular mechanisms underlying acquired epilepsy: the calcium hypothesis of the induction and maintenance of epilepsy." [Pharmacol. Ther. 105(3) (2005) 229-266].
    Pharmacology & therapeutics, 2006, Volume: 111, Issue:1

    Topics: Animals; Anticonvulsants; Brain Injuries; Calcium; Epilepsy; Glutamic Acid; Homeostasis; Humans

2006
Functional changes in astroglial cells in epilepsy.
    Glia, 2006, Volume: 54, Issue:5

    Topics: Animals; Aquaporins; Astrocytes; Brain; Brain Injuries; Epilepsy; Glutamic Acid; Humans; Neoplasms; Potassium Channels; Tuberous Sclerosis; Vesicular Glutamate Transport Proteins

2006
Treatment of interictal epileptiform discharges in cerebral palsy patients without clinical epilepsy: hope for a better outcome in prognosis.
    Clinical neurology and neurosurgery, 2007, Volume: 109, Issue:3

    Topics: Calcium Channels; Cerebral Palsy; Electroencephalography; Epilepsy; Glutamic Acid; Humans; Intracellular Space; Neurons; Neurotoxins; Prognosis; Valproic Acid

2007
An in vitro model of stroke-induced epilepsy: elucidation of the roles of glutamate and calcium in the induction and maintenance of stroke-induced epileptogenesis.
    International review of neurobiology, 2007, Volume: 81

    Topics: Animals; Calcium; Epilepsy; Glutamic Acid; Humans; Stroke

2007
Pathology and pathophysiology of the amygdala in epileptogenesis and epilepsy.
    Epilepsy research, 2008, Volume: 78, Issue:2-3

    Topics: Amygdala; Animals; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Humans

2008
Kainate receptors in epilepsy and excitotoxicity.
    Neuroscience, 2009, Jan-12, Volume: 158, Issue:1

    Topics: Animals; Brain; Epilepsy; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; Kainic Acid; Nerve Net; Neurotoxins; Receptors, Kainic Acid; Synaptic Transmission

2009
Co-localization of excitatory and inhibitory transmitters in the brain.
    Acta neurologica Scandinavica. Supplementum, 2008, Volume: 188

    Topics: Aspartic Acid; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Mossy Fibers, Hippocampal; Synapses

2008
Glutamate, GABA, and CNS disease: a review.
    Neurochemical research, 1983, Volume: 8, Issue:4

    Topics: Brain; Brain Diseases; Energy Metabolism; Epilepsy; Ethanol; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Kindling, Neurologic; Mental Disorders; Neurons; Neurotransmitter Agents; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Glutamate; Synapses

1983
Lamotrigine--a novel approach.
    Seizure, 1994, Volume: 3 Suppl A

    Topics: Anticonvulsants; Brain; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy; Glutamic Acid; Humans; Lamotrigine; Metabolic Clearance Rate; Sodium Channels; Triazines

1994
The role of glutamate in epilepsy and other CNS disorders.
    Neurology, 1994, Volume: 44, Issue:11 Suppl 8

    Topics: Animals; Central Nervous System Diseases; Epilepsy; Glutamic Acid; Humans; Lamotrigine; Mice; N-Methylaspartate; Parkinson Disease; Piperazines; Pyrimidines; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Sodium Channels; Triazines

1994
Metabolic manipulation of neural tissue to counter the hypersynchronous excitation of migraine and epilepsy.
    Neurochemical research, 1993, Volume: 18, Issue:4

    Topics: Animals; Brain; Calcium; Epilepsy; Glutamates; Glutamic Acid; Humans; Migraine Disorders

1993
[Role of excitatory amino acids in neuropathology].
    Medicina, 1995, Volume: 55, Issue:4

    Topics: Animals; Epilepsy; Excitatory Amino Acids; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Ischemia; Neuroglia; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Schizophrenia

1995
Glutamate, GABA and epilepsy.
    Progress in neurobiology, 1995, Volume: 47, Issue:6

    Topics: Animals; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Kindling, Neurologic

1995
The role of glutamate transporters in glutamate homeostasis in the brain.
    The Journal of experimental biology, 1997, Volume: 200, Issue:Pt 2

    Topics: Adenosine Triphosphate; Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Brain; Brain Ischemia; Chloride Channels; Cloning, Molecular; Epilepsy; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Hypoxia, Brain; Nerve Tissue Proteins; Potassium; Signal Transduction; Sodium; Synaptic Transmission

1997
Hypothetical mechanisms for the cellular and neurophysiologic basis of secondary epileptogenesis: proposed role of synaptic reorganization.
    Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 1997, Volume: 14, Issue:2

    Topics: Animals; Dentate Gyrus; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Nerve Net; Rats; Receptors, N-Methyl-D-Aspartate; Synapses

1997
Glutamate in neurologic diseases.
    Journal of child neurology, 1997, Volume: 12, Issue:8

    Topics: Acute Disease; Animals; Brain Injuries; Brain Ischemia; Child; Child Development; Chronic Disease; Disease Models, Animal; Epilepsy; Glutamic Acid; Humans; Nervous System Diseases; Neurodegenerative Diseases; Neuroprotective Agents; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate

1997
Seizures: classification, etiologies, and pathophysiology.
    Clinical techniques in small animal practice, 1998, Volume: 13, Issue:3

    Topics: Animals; Brain Injuries; Cat Diseases; Cats; Cerebral Cortex; Dog Diseases; Dogs; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Neurons; Seizures; Synapses

1998
Electrophysiological substrates for focal epilepsies.
    Progress in brain research, 1998, Volume: 116

    Topics: Animals; Electrophysiology; Epilepsy; Glutamic Acid; Humans; Neural Pathways; Time Factors

1998
Involvement of glutamate in human epileptic activities.
    Progress in brain research, 1998, Volume: 116

    Topics: Animals; Anticonvulsants; Epilepsy; Glutamic Acid; Humans; Synaptic Transmission

1998
Role of metabotropic glutamate receptors in epilepsy.
    Advances in neurology, 1999, Volume: 79

    Topics: Action Potentials; Animals; Epilepsy; Glutamic Acid; Receptors, Metabotropic Glutamate; Synapses

1999
Glutamate receptors and transporters in genetic and acquired models of epilepsy.
    Epilepsy research, 1999, Volume: 36, Issue:2-3

    Topics: Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Epilepsy; Glutamic Acid; Hippocampus; Humans; Kindling, Neurologic; Mice; Mice, Transgenic; Rats; Receptors, Glutamate

1999
Forced normalization: clinical and therapeutic relevance.
    Epilepsia, 1999, Volume: 40 Suppl 10

    Topics: Animals; Cats; Cerebral Cortex; Comorbidity; Diagnosis, Differential; Dopamine; Electroencephalography; Epilepsy; Functional Laterality; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Kindling, Neurologic; Mental Disorders; Neurotransmitter Agents; Psychotic Disorders

1999
Glutamate and epilepsy.
    The Journal of nutrition, 2000, Volume: 130, Issue:4S Suppl

    Topics: Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Epilepsy; Glutamic Acid; Humans; Receptors, Glutamate; Receptors, Metabotropic Glutamate

2000
Transient actions of neurotransmitters during neocortical development.
    Epilepsia, 2000, Volume: 41, Issue:8

    Topics: Animals; Calcium Channels; Cats; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Models, Neurological; Neocortex; Neural Pathways; Neurotransmitter Agents; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Rodentia; Taurine; Thalamus

2000
Selection of antiepileptic drug polytherapy based on mechanisms of action: the evidence reviewed.
    Epilepsia, 2000, Volume: 41, Issue:11

    Topics: Animals; Anticonvulsants; Calcium Channel Agonists; Databases as Topic; Disease Models, Animal; Drug Therapy, Combination; Epilepsy; GABA Agonists; Glutamic Acid; Humans; MEDLINE; Mice; Rabbits; Rats; Sodium Channel Blockers; Treatment Outcome

2000
Pathophysiology of epilepsy.
    Acta neurologica Belgica, 2000, Volume: 100, Issue:4

    Topics: Adult; Animals; Anticonvulsants; Autoimmune Diseases; Calcium; Catecholamines; Cell Movement; Child; Child, Preschool; Electroencephalography; Encephalitis; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Genes, Dominant; Genetic Predisposition to Disease; Glutamic Acid; Hamartoma; Humans; Infant; Infant, Newborn; Ion Channels; Kindling, Neurologic; Membrane Potentials; Neurons; Potassium; Rats; Receptors, AMPA; Receptors, GABA; Receptors, Glutamate; Sodium; Spasms, Infantile; Syndrome; Thalamic Diseases

2000
The mechanisms of action of commonly used antiepileptic drugs.
    Pharmacology & therapeutics, 2001, Volume: 90, Issue:1

    Topics: Animals; Anticonvulsants; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Ion Channels; Molecular Structure; Structure-Activity Relationship; Synaptic Transmission

2001
Role of excitatory amino acids in developmental epilepsies.
    Mental retardation and developmental disabilities research reviews, 2001, Volume: 7, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Epilepsy; Excitatory Amino Acids; Glutamic Acid; Humans; Kinetics; N-Methylaspartate; Synaptic Transmission

2001
[Glutamate receptor antagonists as potential antiepileptic drugs].
    Neurologia i neurochirurgia polska, 2000, Volume: 34 Suppl 8

    Topics: Anticonvulsants; Epilepsy; Glutamic Acid; Humans; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate

2000
Thyrotropin-releasing hormone in the treatment of intractable epilepsy.
    Pediatric neurology, 2002, Volume: 26, Issue:1

    Topics: Anticonvulsants; Brain; Drug Administration Routes; Drug Administration Schedule; Epilepsy; Glutamic Acid; Humans; Neurotransmitter Agents; Syndrome; Thyrotropin-Releasing Hormone

2002
Anticonvulsants: aspects of their mechanisms of action.
    European journal of pain (London, England), 2002, Volume: 6 Suppl A

    Topics: Animals; Anticonvulsants; Central Nervous System; Chronic Disease; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Neural Inhibition; Sodium Channels; Synaptic Transmission

2002
Modulatory role of GABA receptor subtypes and glutamate receptors in the anticonvulsant effect of barbiturates.
    Epilepsy research. Supplement, 1992, Volume: 8

    Topics: Animals; Anticonvulsants; Barbiturates; Brain; Culture Techniques; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Receptors, GABA-A; Receptors, Glutamate; Synaptic Transmission

1992
Regulatory role of astrocytes for neuronal biosynthesis and homeostasis of glutamate and GABA.
    Progress in brain research, 1992, Volume: 94

    Topics: Alanine; Amino Acids; Animals; Astrocytes; Brain; Cell Communication; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Homeostasis; Humans; Nerve Degeneration; Neurons

1992
Rational basis for the development of new antiepileptic drugs.
    Epilepsy research. Supplement, 1991, Volume: 3

    Topics: Animals; Anticonvulsants; Aspartic Acid; Brain; Electroencephalography; Epilepsy; Glutamates; Glutamic Acid; Humans; Synaptic Transmission

1991
Excitatory amino acids in epilepsy and novel anti-epileptic drugs.
    Epilepsy research. Supplement, 1991, Volume: 3

    Topics: Animals; Anticonvulsants; Aspartic Acid; Epilepsy; Glutamates; Glutamic Acid; Humans; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission

1991
Excitatory amino acid transmitters in epilepsy.
    Epilepsia, 1991, Volume: 32 Suppl 2

    Topics: Anticonvulsants; Aspartic Acid; Epilepsy; Epilepsy, Temporal Lobe; Glutamates; Glutamic Acid; Humans; Ion Channels; Lamotrigine; Neurotransmitter Agents; Triazines

1991
Neuronal discharge hypersynchrony and the intracranial water balance in relation to glutamic acid and taurine redistribution: migraine and epilepsy.
    Progress in clinical and biological research, 1990, Volume: 351

    Topics: Action Potentials; Animals; Brain; Epilepsy; Glutamates; Glutamic Acid; Humans; Migraine Disorders; Neurons; Taurine; Water-Electrolyte Balance

1990
Possible therapeutic applications of antagonists of excitatory amino acid neurotransmitters.
    Clinical science (London, England : 1979), 1985, Volume: 68, Issue:2

    Topics: Alzheimer Disease; Animals; Aspartic Acid; Basal Ganglia Diseases; Brain; Brain Ischemia; Epilepsy; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Humans; Huntington Disease; Mice; Movement Disorders; Nerve Degeneration; Neurotransmitter Agents; Parkinson Disease; Rats

1985
Neuron-glia relationships in human and experimental epilepsy: a biochemical point of view.
    Advances in neurology, 1986, Volume: 44

    Topics: Amino Acids; Animals; Biological Transport; Brain; Carbonic Anhydrases; Epilepsy; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Homeostasis; Humans; Ions; Neuroglia; Neurons; Neurotransmitter Agents; Potassium; Sodium-Potassium-Exchanging ATPase

1986
Cellular and molecular events underlying epileptic brain damage.
    Annals of the New York Academy of Sciences, 1986, Volume: 462

    Topics: Acidosis; Animals; Brain; Brain Damage, Chronic; Calcium; Cell Survival; Cerebral Infarction; Electroconvulsive Therapy; Electroshock; Epilepsy; Fatty Acids, Nonesterified; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Nucleotides; Oxygen Consumption; Phospholipids; Potassium; Proteins; Pyruvates; Pyruvic Acid

1986
Influence of precursors on brain GABA level.
    Clinical neuropharmacology, 1987, Volume: 10, Issue:1

    Topics: Animals; Brain; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Humans; Sodium Glutamate

1987
Endogenous excitotoxic agents.
    Ciba Foundation symposium, 1987, Volume: 126

    Topics: Animals; Aspartic Acid; Cell Survival; Central Nervous System; Dementia; Epilepsy; Glutamates; Glutamic Acid; Humans; Huntington Disease; Models, Neurological; Neurons; Quinolinic Acid; Quinolinic Acids

1987

Trials

6 trial(s) available for glutamic acid and Aura

ArticleYear
Investigation of the low glutamate diet as an adjunct treatment for pediatric epilepsy: A pilot randomized controlled trial.
    Seizure, 2023, Volume: 106

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; COVID-19; Diet; Drug Resistant Epilepsy; Epilepsy; Glutamic Acid; Humans; Pilot Projects; Seizures; Young Adult

2023
Ketter's hypothesis of the mood effects of antiepileptic drugs coupled to the mechanism of action of topiramate and levetiracetam.
    Epilepsy & behavior : E&B, 2005, Volume: 6, Issue:3

    Topics: Adult; Anticonvulsants; Chi-Square Distribution; Demography; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Fructose; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Levetiracetam; Male; Middle Aged; Models, Biological; Mood Disorders; Odds Ratio; Piracetam; Time Factors; Topiramate

2005
Quantitative glutamate spectroscopic imaging of the human hippocampus.
    NMR in biomedicine, 2006, Volume: 19, Issue:2

    Topics: Adult; Algorithms; Epilepsy; Female; Glutamic Acid; Hippocampus; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurotransmitter Agents; Tissue Distribution

2006
Add-on lamotrigine treatment and plasma glutamate levels in epilepsy: relation to treatment response.
    Epilepsy research, 2006, Volume: 70, Issue:2-3

    Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Epilepsy; Female; Glutamic Acid; Humans; Lamotrigine; Male; Time Factors; Triazines; Valproic Acid

2006
Quantitative analysis of short echo time (1)H-MRSI of cerebral gray and white matter.
    Magnetic resonance in medicine, 2000, Volume: 44, Issue:3

    Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Calibration; Cerebrospinal Fluid; Choline; Creatine; Dipeptides; Epilepsy; Female; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis; Phantoms, Imaging; Regression Analysis; Sensitivity and Specificity

2000
Quantitative short echo time proton magnetic resonance spectroscopic imaging study of malformations of cortical development causing epilepsy.
    Brain : a journal of neurology, 2001, Volume: 124, Issue:Pt 2

    Topics: Adult; Analysis of Variance; Aspartic Acid; Cerebral Cortex; Choline; Creatine; Dipeptides; Epilepsy; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Imaging; Male; Middle Aged; Nervous System Malformations; Phosphocreatine; Reference Values

2001

Other Studies

371 other study(ies) available for glutamic acid and Aura

ArticleYear
Loss of glutamate transporter eaat2a leads to aberrant neuronal excitability, recurrent epileptic seizures, and basal hypoactivity.
    Glia, 2022, Volume: 70, Issue:1

    Topics: Animals; Astrocytes; Epilepsy; Excitatory Amino Acid Transporter 2; Glutamic Acid; Neurons; Seizures; Zebrafish

2022
Glutamic Acid and Total Creatine as Predictive Markers for Epilepsy in Glioblastoma by Using Magnetic Resonance Spectroscopy Before Surgery.
    World neurosurgery, 2022, Volume: 160

    Topics: Creatine; Epilepsy; Glioblastoma; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Quality of Life; Reproducibility of Results

2022
Sulfasalazine decreases astrogliosis-mediated seizure burden.
    Epilepsia, 2022, Volume: 63, Issue:4

    Topics: Animals; Antiporters; Electroencephalography; Epilepsy; Gliosis; Glutamic Acid; Humans; Mice; Seizures; Sulfasalazine

2022
High frequency oscillations play important roles in development of epileptogenesis/ictogenesis via activation of astroglial signallings.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 149

    Topics: Animals; Astrocytes; Carbamazepine; Connexin 43; Epilepsy; Glutamic Acid; Proto-Oncogene Proteins c-akt; Rats

2022
Ketone Body Rescued Seizure Behavior of LRP1 Deficiency in Drosophila by Modulating Glutamate Transport.
    Journal of molecular neuroscience : MN, 2022, Volume: 72, Issue:8

    Topics: Animals; Drosophila; Epilepsy; Glutamic Acid; Ketone Bodies; Seizures; Sucrose

2022
Blocking ERK-DAPK1 Axis Attenuates Glutamate Excitotoxicity in Epilepsy.
    International journal of molecular sciences, 2022, Jun-07, Volume: 23, Issue:12

    Topics: Animals; Death-Associated Protein Kinases; Epilepsy; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Humans; Kainic Acid; Mice; Seizures

2022
Quercetin alleviates kainic acid-induced seizure by inhibiting the Nrf2-mediated ferroptosis pathway.
    Free radical biology & medicine, 2022, Volume: 191

    Topics: Animals; Anticonvulsants; Epilepsy; Ferroptosis; Glutamic Acid; Kainic Acid; Mice; Neuroprotective Agents; NF-E2-Related Factor 2; Polyphenols; Quercetin; Seizures; Signal Transduction; Sirtuin 1

2022
Mapping hippocampal glutamate in mesial temporal lobe epilepsy with glutamate weighted CEST (GluCEST) imaging.
    Human brain mapping, 2023, 02-01, Volume: 44, Issue:2

    Topics: Epilepsy; Epilepsy, Temporal Lobe; Glutamic Acid; Hippocampus; Humans; Magnetic Resonance Imaging; Sclerosis

2023
Functional investigation of SLC1A2 variants associated with epilepsy.
    Cell death & disease, 2022, 12-21, Volume: 13, Issue:12

    Topics: Animals; Biological Transport; Calcium; Calcium Signaling; Epilepsy; Glutamic Acid; Mice; ORAI1 Protein; Stromal Interaction Molecule 1

2022
Perampanel as precision therapy in rare genetic epilepsies.
    Epilepsia, 2023, Volume: 64, Issue:4

    Topics: Anticonvulsants; Child; Epilepsies, Partial; Epilepsy; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Protocadherins; Pyridones; Retrospective Studies; Seizures; Treatment Outcome

2023
PtNPs/rGO-GluOx/mPD Directionally Electroplated Dual-Mode Microelectrode Arrays for Detecting the Synergistic Relationship between the Cortex and Hippocampus of Epileptic Rats.
    ACS sensors, 2023, 04-28, Volume: 8, Issue:4

    Topics: Animals; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Microelectrodes; Rats; Rats, Sprague-Dawley

2023
Dopamine and Glutamate Crosstalk Worsen the Seizure Outcome in TLE-HS Patients.
    Molecular neurobiology, 2023, Volume: 60, Issue:9

    Topics: Dopamine; Drug Resistant Epilepsy; Epilepsy; Epilepsy, Temporal Lobe; Glutamic Acid; Hippocampus; Humans; Treatment Outcome

2023
A stimuli-responsive nanocarrier for diagnosis of seizures and inhibition of glutaminase in epilepsy.
    International journal of pharmaceutics, 2023, Jul-25, Volume: 642

    Topics: Animals; Epilepsy; Glutamic Acid; Glutaminase; Rats; Rats, Wistar; Seizures

2023
Astroglial Alterations in the Hippocampus of Rats Submitted to a Single Trans-Cranial Direct Current Stimulation Trial.
    Neurochemical research, 2023, Volume: 48, Issue:11

    Topics: Animals; Astrocytes; Epilepsy; Glutamate-Ammonia Ligase; Glutamic Acid; Hippocampus; Rats; Transcranial Direct Current Stimulation

2023
Effects of probiotics on GABA/glutamate and oxidative stress in PTZ- induced acute seizure model in rats.
    Epilepsy research, 2023, Volume: 195

    Topics: Animals; Anticonvulsants; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Male; Oxidative Stress; Pentylenetetrazole; Probiotics; Rats; Rats, Wistar; Seizures

2023
Glia-neuron interactions underlie state transitions to generalized seizures.
    Nature communications, 2019, 08-23, Volume: 10, Issue:1

    Topics: Animals; Animals, Genetically Modified; Brain; Cell Communication; Cortical Excitability; Disease Models, Animal; Epilepsy; Gap Junctions; Glutamic Acid; Humans; Microscopy, Confocal; Nerve Net; Neuroglia; Neurons; Optical Imaging; Optogenetics; Patch-Clamp Techniques; Seizures; Zebrafish

2019
A combined astrocyte - G-lymphatic model of epilepsy initiation, maintenance and termination.
    Medical hypotheses, 2019, Volume: 133

    Topics: Anesthesia; Animals; Astrocytes; Brain; Circadian Rhythm; Epilepsy; Glutamic Acid; Glymphatic System; Humans; Models, Neurological; Neuroglia; Neurons; Norepinephrine; Potassium; Sleep; Sleep Deprivation; Unconsciousness

2019
Inhibition of human microsomal PGE2 synthase-1 reduces seizure-induced increases of P-glycoprotein expression and activity at the blood-brain barrier.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Brain; Capillaries; Cyclooxygenase 2; Dinoprostone; Epilepsy; Female; Glutamic Acid; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microsomes; Prostaglandin-E Synthases; Rats; Rats, Sprague-Dawley; Seizures; Signal Transduction; Up-Regulation

2019
Cytosolic phospholipase A2 is a key regulator of blood-brain barrier function in epilepsy.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:12

    Topics: Animals; Blood-Brain Barrier; Brain; Capillaries; Epilepsy; Gene Expression Regulation, Enzymologic; Genotype; Glutamic Acid; Group IV Phospholipases A2; Male; Mice; Rats; Rats, Sprague-Dawley

2019
Endothelial Cdk5 deficit leads to the development of spontaneous epilepsy through CXCL1/CXCR2-mediated reactive astrogliosis.
    The Journal of experimental medicine, 2020, 01-06, Volume: 217, Issue:1

    Topics: Animals; Astrocytes; Blood-Brain Barrier; Cells, Cultured; Chemokine CXCL1; Cyclin-Dependent Kinase 5; Endothelial Cells; Epilepsy; Gliosis; Glutamic Acid; Mice; Mice, Knockout; Neurons; Receptors, Interleukin-8B; Seizures; Signal Transduction

2020
Ceftriaxone Treatment Affects EAAT2 Expression and Glutamatergic Neurotransmission and Exerts a Weak Anticonvulsant Effect in Young Rats.
    International journal of molecular sciences, 2019, Nov-21, Volume: 20, Issue:23

    Topics: Animals; Anticonvulsants; Ceftriaxone; Epilepsy; Excitatory Amino Acid Transporter 2; Excitatory Postsynaptic Potentials; Gene Expression; Glutamic Acid; Hippocampus; Male; Rats, Wistar; Seizures; Synaptic Transmission; Temporal Lobe

2019
Modulation of epileptogenesis: A paradigm for the integration of enzyme-based microelectrode arrays and optogenetics.
    Epilepsy research, 2020, Volume: 159

    Topics: Animals; Electrodes, Implanted; Epilepsy; Glutamic Acid; Hippocampus; Male; Nerve Net; Neurons; Optogenetics; Rats; Rats, Sprague-Dawley; Synaptic Transmission

2020
Does Neuronal Activity Promote Glioma Progression?
    Trends in cancer, 2020, Volume: 6, Issue:1

    Topics: Epilepsy; Glioma; Glutamic Acid; Humans; Neurons; Signal Transduction

2020
Imaging the glutamate synapse.
    Nature medicine, 2020, Volume: 26, Issue:2

    Topics: Allosteric Site; Animals; Cell Proliferation; Dendrites; Epilepsy; Glutamic Acid; Glutamine; Humans; Ligands; Neurons; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, AMPA; Synapses; Synaptic Transmission; Temporal Lobe

2020
Glutamatergic pathway in depressive-like behavior associated with pentylenetetrazole rat model of epilepsy with history of prolonged febrile seizures.
    Life sciences, 2020, Jul-15, Volume: 253

    Topics: Amygdala; Animals; Brain-Derived Neurotrophic Factor; Depression; Epilepsy; Excitatory Amino Acid Transporter 1; Glutamate Synthase; Glutamic Acid; Hippocampus; Male; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Seizures, Febrile

2020
Anandamide Signaling Augmentation Rescues Amygdala Synaptic Function and Comorbid Emotional Alterations in a Model of Epilepsy.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020, 07-29, Volume: 40, Issue:31

    Topics: Affective Symptoms; Amidohydrolases; Amygdala; Animals; Anxiety; Arachidonic Acids; Endocannabinoids; Epilepsy; Fear; gamma-Aminobutyric Acid; Glutamic Acid; Kindling, Neurologic; Male; Polyunsaturated Alkamides; Rats; Rats, Long-Evans; Signal Transduction; Synapses

2020
Biochemical underpinning of Lateralized Periodic Discharges: Regional glutamate overload?
    Epilepsy research, 2020, Volume: 167

    Topics: Electroencephalography; Epilepsy; Glutamic Acid; Humans; Patient Discharge

2020
Transitions between neocortical seizure and non-seizure-like states and their association with presynaptic glutamate release.
    Neurobiology of disease, 2020, Volume: 146

    Topics: Adult; Animals; Epilepsy; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Humans; Male; Mice, Inbred C57BL; Neocortex; Patch-Clamp Techniques; Seizures; Synapses; Synaptic Transmission; Young Adult

2020
Dietary omega-3 fatty acids prevent neonatal seizure-induced early alterations in the hippocampal glutamatergic system and memory deficits in adulthood.
    Nutritional neuroscience, 2022, Volume: 25, Issue:5

    Topics: Animals; Diet; Epilepsy; Fatty Acids, Omega-3; Female; Glutamic Acid; Hippocampus; Kainic Acid; Male; Memory Disorders; Pregnancy; Rats; Rats, Wistar; Seizures

2022
Seven-tesla quantitative magnetic resonance spectroscopy of glutamate, γ-aminobutyric acid, and glutathione in the posterior cingulate cortex/precuneus in patients with epilepsy.
    Epilepsia, 2020, Volume: 61, Issue:12

    Topics: Adult; Aged; Case-Control Studies; Epilepsy; Epilepsy, Generalized; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glutamic Acid; Glutathione; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Parietal Lobe; Young Adult

2020
Inhibition of p38 MAPK regulates epileptic severity by decreasing expression levels of A1R and ENT1.
    Molecular medicine reports, 2020, Volume: 22, Issue:6

    Topics: Animals; Anticonvulsants; Brain; Epilepsy; Equilibrative Nucleoside Transporter 1; Glutamic Acid; Hippocampus; Imidazoles; Male; Neurons; p38 Mitogen-Activated Protein Kinases; Pilocarpine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Seizures; Signal Transduction; Status Epilepticus

2020
TRIM27-mediated ubiquitination of PPARγ promotes glutamate-induced cell apoptosis and inflammation.
    Experimental cell research, 2021, 03-01, Volume: 400, Issue:1

    Topics: Apoptosis; Brain; Case-Control Studies; DNA-Binding Proteins; Epilepsy; Glutamic Acid; Humans; Inflammation; Nuclear Proteins; PPAR gamma; Ubiquitination

2021
Glutamatergic System is Affected in Brain from an Hyperthermia-Induced Seizures Rat Model.
    Cellular and molecular neurobiology, 2022, Volume: 42, Issue:5

    Topics: Animals; Brain; Epilepsy; Glutamic Acid; Hyperthermia, Induced; Rats; Seizures, Febrile

2022
Hippocampal astrocytic neogenin regulating glutamate uptake, a critical pathway for preventing epileptic response.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 04-20, Volume: 118, Issue:16

    Topics: Animals; Astrocytes; Biological Transport; Epilepsy; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Female; Glutamic Acid; Hippocampus; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Seizures; Signal Transduction; Synaptic Potentials

2021
Altered synaptic glutamate homeostasis contributes to cognitive decline in young APP/PSEN1 mice.
    Neurobiology of disease, 2021, Volume: 158

    Topics: Amyloid beta-Protein Precursor; Animals; Cognitive Dysfunction; Electroencephalography; Epilepsy; Female; Glutamic Acid; Hippocampus; Homeostasis; Kainic Acid; Long-Term Potentiation; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Plaque, Amyloid; Presenilin-1

2021
Dietary modulation of cortical excitation and inhibition.
    Journal of psychopharmacology (Oxford, England), 2017, Volume: 31, Issue:5

    Topics: Adult; Brain; Diet; Electroencephalography; Epilepsy; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Inhibition, Psychological; Male; Neural Inhibition; Neurotransmitter Agents; Synaptic Transmission; Young Adult

2017
Targeting glutamate transporter-1 in neurological diseases.
    Oncotarget, 2017, Apr-04, Volume: 8, Issue:14

    Topics: Alzheimer Disease; Amino Acid Transport System X-AG; Amyotrophic Lateral Sclerosis; Animals; Astrocytes; Disease Progression; Epilepsy; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glutamate Plasma Membrane Transport Proteins; Glutamates; Glutamic Acid; Homeostasis; Humans; Mice; Models, Biological; Nervous System Diseases; Neurodegenerative Diseases

2017
Current Study of the Mechanism of Action of the Potential Anti-Epileptic Agent Q808.
    Molecules (Basel, Switzerland), 2017, Jul-07, Volume: 22, Issue:7

    Topics: Animals; Anticonvulsants; Brain; Electroshock; Epilepsy; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Male; Neurons; Neurotransmitter Agents; Phthalazines; Rats, Sprague-Dawley; Receptors, GABA; Tetrazoles

2017
Impairment of GABAergic system contributes to epileptogenesis in glutaric acidemia type I.
    Epilepsia, 2017, Volume: 58, Issue:10

    Topics: Amino Acid Metabolism, Inborn Errors; Animals; Blotting, Western; Brain; Brain Diseases, Metabolic; Chromatography, High Pressure Liquid; Epilepsy; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Glutaryl-CoA Dehydrogenase; Mice; Mice, Knockout; Pentylenetetrazole; Synaptosomes

2017
SSa ameliorates the Glu uptaking capacity of astrocytes in epilepsy via AP-1/miR-155/GLAST.
    Biochemical and biophysical research communications, 2017, 11-25, Volume: 493, Issue:3

    Topics: Animals; Astrocytes; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Transporter 1; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; MicroRNAs; Oleanolic Acid; Pentylenetetrazole; Proto-Oncogene Proteins c-fos; Rats, Wistar; Saponins; Transcription Factor AP-1

2017
Epigenetic control of epilepsy target genes contributes to a cellular memory of epileptogenesis in cultured rat hippocampal neurons.
    Acta neuropathologica communications, 2017, Oct-31, Volume: 5, Issue:1

    Topics: Action Potentials; Animals; Animals, Newborn; Cells, Cultured; DNA Methylation; Epigenesis, Genetic; Epilepsy; Excitatory Amino Acid Agents; Gene Expression; Glutamic Acid; Hippocampus; Microtubule-Associated Proteins; Models, Biological; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Tetrodotoxin; Valine

2017
Modification of the natural progression of epileptogenesis by means of biperiden in the pilocarpine model of epilepsy.
    Epilepsy research, 2017, Volume: 138

    Topics: Action Potentials; Animals; Autonomic Nervous System; Biperiden; Chronic Disease; Cytokines; Disease Models, Animal; Disease Progression; Epilepsy; Exploratory Behavior; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Maze Learning; Muscarinic Agonists; Muscarinic Antagonists; Pilocarpine; Rats; Rats, Wistar

2017
LC-MS/MS imaging with thermal film-based laser microdissection.
    Analytical and bioanalytical chemistry, 2018, Volume: 410, Issue:2

    Topics: Acetylcholine; Animals; Choline; Chromatography, Liquid; Epilepsy; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Laser Capture Microdissection; Mice, Inbred C57BL; Neurotransmitter Agents; Pilocarpine; Tandem Mass Spectrometry

2018
Glutamate Excitotoxicity Linked to Spermine Oxidase Overexpression.
    Molecular neurobiology, 2018, Volume: 55, Issue:9

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Amino Acid Transport System y+; Animals; Behavior, Animal; Brain; Deoxyguanosine; Epilepsy; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamic Acid; Mice, Transgenic; Models, Biological; Neuroglia; Neurotoxins; NF-E2-Related Factor 2; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Protein Subunits; Protein Transport; Receptors, AMPA; Sulfasalazine; Synaptosomes

2018
Na
    Neuroscience, 2018, 05-01, Volume: 377

    Topics: Animals; Antibodies; Anticonvulsants; Caspase 3; Disease Models, Animal; Drug Evaluation, Preclinical; Epilepsy; Glucose; Glutamic Acid; Hippocampus; Male; Mice, Inbred C57BL; Oxidation-Reduction; Pilocarpine; Sodium-Potassium-Exchanging ATPase; Tissue Culture Techniques

2018
Indispensable Amino Acid-Deficient Diets Induce Seizures in Ketogenic Diet-Fed Rodents, Demonstrating a Role for Amino Acid Balance in Dietary Treatments for Epilepsy.
    The Journal of nutrition, 2018, 03-01, Volume: 148, Issue:3

    Topics: Amino Acids, Essential; Animals; Brain; Deficiency Diseases; Diet, Ketogenic; Dietary Proteins; Epilepsy; Feeding Behavior; Female; Gerbillinae; Glutamic Acid; Male; Nutritional Requirements; Rats, Sprague-Dawley; Seizures; Threonine

2018
High field imaging of large-scale neurotransmitter networks: Proof of concept and initial application to epilepsy.
    NeuroImage. Clinical, 2018, Volume: 19

    Topics: Adult; Aged; Brain; Brain Mapping; Epilepsy; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Net; Neural Pathways; Neurons; Neurotransmitter Agents; Young Adult

2018
Selective deletion of glutamine synthetase in the mouse cerebral cortex induces glial dysfunction and vascular impairment that precede epilepsy and neurodegeneration.
    Neurochemistry international, 2019, Volume: 123

    Topics: Amino Acid Transport System X-AG; Animals; Astrocytes; Cerebral Cortex; Disease Models, Animal; Epilepsy; Female; Glial Fibrillary Acidic Protein; Glutamate-Ammonia Ligase; Glutamic Acid; Hippocampus; Male; Mice; Neuroglia; Receptors, Glutamate

2019
Echinacoside, an Active Constituent of Cistanche Herba, Exerts a Neuroprotective Effect in a Kainic Acid Rat Model by Inhibiting Inflammatory Processes and Activating the Akt/GSK3β Pathway.
    Biological & pharmaceutical bulletin, 2018, Nov-01, Volume: 41, Issue:11

    Topics: Animals; Brain; Cistanche; Cytokines; Disease Models, Animal; Epilepsy; Glutamic Acid; Glycogen Synthase Kinase 3 beta; Glycosides; Inflammation; Kainic Acid; Male; Microglia; Neuroprotective Agents; Neurotoxicity Syndromes; Phosphorylation; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats, Sprague-Dawley; Seizures; Signal Transduction

2018
The Na+/H+ Exchanger Nhe1 Modulates Network Excitability via GABA Release.
    Cerebral cortex (New York, N.Y. : 1991), 2019, 09-13, Volume: 29, Issue:10

    Topics: Animals; CA1 Region, Hippocampal; Epilepsy; Female; GABAergic Neurons; gamma-Aminobutyric Acid; Glutamic Acid; Interneurons; Male; Membrane Potentials; Mice, Inbred C57BL; Mice, Transgenic; Presynaptic Terminals; Sodium-Hydrogen Exchanger 1; Vesicular Glutamate Transport Protein 1; Vesicular Inhibitory Amino Acid Transport Proteins

2019
Investigating the role of interleukin-1 beta and glutamate in inflammatory bowel disease and epilepsy using discovery browsing.
    Journal of biomedical semantics, 2018, 12-27, Volume: 9, Issue:1

    Topics: Brain; Data Mining; Epilepsy; Glutamic Acid; Humans; Inflammatory Bowel Diseases; Interleukin-1beta; MEDLINE; Semantics

2018
Commonalities and differences in extracellular levels of hippocampal acetylcholine and amino acid neurotransmitters during status epilepticus and subsequent epileptogenesis in two rat models of temporal lobe epilepsy.
    Brain research, 2019, 06-01, Volume: 1712

    Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Disease Models, Animal; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; Female; Glutamic Acid; Hippocampus; Lysine; Microdialysis; Neurotransmitter Agents; Pilocarpine; Rats; Scopolamine; Seizures; Status Epilepticus; Temporal Lobe

2019
AMPA receptor antagonist perampanel affects glioblastoma cell growth and glutamate release in vitro.
    PloS one, 2019, Volume: 14, Issue:2

    Topics: Anticonvulsants; Antineoplastic Agents; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Epilepsy; Glioblastoma; Glutamic Acid; Humans; Nitriles; Pyridones; Receptors, AMPA; Seizures; Up-Regulation; Valproic Acid

2019
Glutamate weighted imaging contrast in gliomas with 7 Tesla magnetic resonance imaging.
    NeuroImage. Clinical, 2019, Volume: 22

    Topics: Adult; Brain Neoplasms; Epilepsy; Female; Glioma; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged

2019
The Anticonvulsant Effects of Baldrinal on Pilocarpine-Induced convulsion in Adult Male Mice.
    Molecules (Basel, Switzerland), 2019, Apr-24, Volume: 24, Issue:8

    Topics: Animals; Anticonvulsants; Brain; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Iridoids; Mice; Pilocarpine; Seizures

2019
Neurochemical investigation of multiple locally induced seizures using microdialysis sampling: Epilepsy effects on glutamate release.
    Brain research, 2019, 11-01, Volume: 1722

    Topics: 3-Mercaptopropionic Acid; Animals; Disease Models, Animal; Epilepsy; Glutamic Acid; Hippocampus; Male; Microdialysis; Rats, Wistar; Seizures

2019
An amperometric glutamate biosensor based on immobilization of glutamate oxidase onto carboxylated multiwalled carbon nanotubes/gold nanoparticles/chitosan composite film modified Au electrode.
    Biosensors & bioelectronics, 2013, Sep-15, Volume: 47

    Topics: Amino Acid Oxidoreductases; Biosensing Techniques; Chitosan; Dielectric Spectroscopy; Electrodes; Enzymes, Immobilized; Epilepsy; Female; Glutamic Acid; Gold; Humans; Hydrogen Peroxide; Limit of Detection; Male; Metal Nanoparticles; Nanotubes, Carbon

2013
EPAC inhibition of SUR1 receptor increases glutamate release and seizure vulnerability.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, May-15, Volume: 33, Issue:20

    Topics: Animals; Bicuculline; Biophysics; Disease Models, Animal; Electric Stimulation; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Glutamic Acid; Guanine Nucleotide Exchange Factors; Hippocampus; Humans; Immunoprecipitation; In Vitro Techniques; Kainic Acid; KATP Channels; Male; Membrane Potentials; Mice; Mice, Knockout; Patch-Clamp Techniques; Probability; Protein Binding; Quinoxalines; Synaptosomes; Transduction, Genetic

2013
Long-duration epilepsy affects cell morphology and glutamatergic synapses in type IIB focal cortical dysplasia.
    Acta neuropathologica, 2013, Volume: 126, Issue:2

    Topics: Adolescent; Adult; Brain Diseases; Cell Size; Child; Child, Preschool; Epilepsy; Female; Gliosis; Glutamic Acid; Humans; Infant; Male; Malformations of Cortical Development; Malformations of Cortical Development, Group I; Middle Aged; Neuronal Plasticity; Neurons; Receptors, N-Methyl-D-Aspartate; Synapses; Vesicular Glutamate Transport Protein 1; Young Adult

2013
Comparison of concentrations of γ-aminobutyric acid and glutamate in cerebrospinal fluid of dogs with idiopathic epilepsy with and without seizure-related magnetic resonance imaging hyperintense areas in the limbic system.
    American journal of veterinary research, 2013, Volume: 74, Issue:8

    Topics: Animals; Dog Diseases; Dogs; Epilepsy; Female; gamma-Aminobutyric Acid; Glutamic Acid; Limbic System; Magnetic Resonance Imaging; Male

2013
Dehydroepiandrosterone's antiepileptic action in FeCl3-induced epileptogenesis involves upregulation of glutamate transporters.
    Epilepsy research, 2013, Volume: 106, Issue:1-2

    Topics: Amino Acid Transport System X-AG; Animals; Anticonvulsants; Chlorides; Dehydroepiandrosterone; Electroencephalography; Electrophysiological Phenomena; Epilepsy; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Ferric Compounds; Glutamic Acid; Male; Polymerase Chain Reaction; Rats; Rats, Wistar; RNA; Seizures

2013
Increased ratio of glutamate/glutamine to creatine in the right hippocampus contributes to depressive symptoms in patients with epilepsy.
    Epilepsy & behavior : E&B, 2013, Volume: 29, Issue:1

    Topics: Adolescent; Adult; Creatine; Depression; Epilepsy; Female; Functional Laterality; Glutamic Acid; Glutamine; Hippocampus; Humans; Male; Middle Aged; Neuropsychological Tests; Prospective Studies; Psychiatric Status Rating Scales; Young Adult

2013
Gas chromatography-mass spectrometry-based metabolic profiling of cerebrospinal fluid from epileptic dogs.
    The Journal of veterinary medical science, 2014, Volume: 76, Issue:4

    Topics: Animals; Cerebrospinal Fluid; Dog Diseases; Dogs; Epilepsy; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Metabolome

2014
Curcumol from Rhizoma Curcumae suppresses epileptic seizure by facilitation of GABA(A) receptors.
    Neuropharmacology, 2014, Volume: 81

    Topics: Animals; Anticonvulsants; Cells, Cultured; Curcuma; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Exploratory Behavior; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Inhibitory Postsynaptic Potentials; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Receptors, GABA-A; Sesquiterpenes

2014
Traumatic Brain Injury Increases Cortical Glutamate Network Activity by Compromising GABAergic Control.
    Cerebral cortex (New York, N.Y. : 1991), 2015, Volume: 25, Issue:8

    Topics: Animals; Astrocytes; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Postsynaptic Potentials; GABAergic Neurons; Glutamic Acid; Inhibitory Postsynaptic Potentials; Male; Mice, Inbred C57BL; Neural Pathways; Parvalbumins; Somatostatin; Tissue Culture Techniques

2015
Transient muscarinic and glutamatergic stimulation of neural stem cells triggers acute and persistent changes in differentiation.
    Neurobiology of disease, 2014, Volume: 70

    Topics: Animals; Chronic Disease; Disease Models, Animal; Epilepsy; GABAergic Neurons; Gap Junctions; Glutamic Acid; Hippocampus; Humans; Induced Pluripotent Stem Cells; Male; Mice; Muscarinic Agonists; Neural Stem Cells; Neurogenesis; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, Muscarinic

2014
Gabapentin attenuates hyperexcitability in the freeze-lesion model of developmental cortical malformation.
    Neurobiology of disease, 2014, Volume: 71

    Topics: Age Factors; Amines; Animals; Animals, Newborn; Anticonvulsants; Calcium Channels; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electric Stimulation; Epilepsy; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Freezing; Gabapentin; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamic Acid; In Vitro Techniques; Kainic Acid; Malformations of Cortical Development; Mice; Mice, Inbred C57BL; Neuroimaging; Patch-Clamp Techniques; Somatosensory Cortex; Thrombospondins

2014
Glutamate-mediated upregulation of the multidrug resistance protein 2 in porcine and human brain capillaries.
    The Journal of pharmacology and experimental therapeutics, 2015, Volume: 352, Issue:2

    Topics: Adolescent; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Biological Transport; Blood-Brain Barrier; Brain; Capillaries; Child; Child, Preschool; Cyclooxygenase 2; Dose-Response Relationship, Drug; Epilepsy; Female; Glutamic Acid; Humans; In Vitro Techniques; Male; Receptors, N-Methyl-D-Aspartate; Swine; Up-Regulation

2015
Changes in the behavior and oscillatory activity in cortical and subcortical brain structures induced by repeated l-glutamate injections to the medial septal area in guinea pigs.
    Epilepsy research, 2015, Volume: 109

    Topics: Animals; Brain; Brain Waves; Electrodes, Implanted; Epilepsy; Female; Glutamic Acid; Guinea Pigs; Male; Seizures

2015
Extracellular glutamate exposure facilitates group I mGluR-mediated epileptogenesis in the hippocampus.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Jan-07, Volume: 35, Issue:1

    Topics: Animals; Epilepsy; Extracellular Space; Fragile X Mental Retardation Protein; Glutamic Acid; Hippocampus; Mice; Mice, 129 Strain; Mice, Knockout; Organ Culture Techniques; Receptors, Metabotropic Glutamate

2015
Rapid adaptation of rat brain and liver metabolism to a ketogenic diet: an integrated study using (1)H- and (13)C-NMR spectroscopy.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2015, Volume: 35, Issue:7

    Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Brain; Diet, Ketogenic; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Ketone Bodies; Liver; Magnetic Resonance Spectroscopy; Male; Rats, Sprague-Dawley

2015
Conditional deletion of the glutamate transporter GLT-1 reveals that astrocytic GLT-1 protects against fatal epilepsy while neuronal GLT-1 contributes significantly to glutamate uptake into synaptosomes.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Apr-01, Volume: 35, Issue:13

    Topics: Animals; Astrocytes; Body Weight; Brain; Electroencephalography; Epilepsy; Excitatory Amino Acid Transporter 2; Female; Glutamic Acid; Liposomes; Male; Mice; Mice, Knockout; Neurons; Presynaptic Terminals; Synaptosomes

2015
Anticonvulsant and Sedative Effects of Eudesmin isolated from Acorus tatarinowii on mice and rats.
    Phytotherapy research : PTR, 2015, Volume: 29, Issue:7

    Topics: Acorus; Animals; Anticonvulsants; Brain; Caspase 3; Disease Models, Animal; Electroshock; Epilepsy; Furans; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Hypnotics and Sedatives; Lignans; Male; Mice; Mice, Inbred ICR; Motor Activity; Pentobarbital; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures

2015
Effects of 3-aminoglutarate, a "silent" false transmitter for glutamate neurons, on synaptic transmission and epileptiform activity.
    Neuropharmacology, 2015, Volume: 97

    Topics: Animals; Anticonvulsants; Brain; Cells, Cultured; Epilepsy; Excitatory Postsynaptic Potentials; Glutamates; Glutamic Acid; Mice, Inbred C57BL; Miniature Postsynaptic Potentials; Neurons; Neurotransmitter Agents; Patch-Clamp Techniques; Receptors, Glutamate; Synapses; Synaptic Transmission; Tissue Culture Techniques

2015
Increased extracellular levels of glutamate in the hippocampus of chronically epileptic rats.
    Neuroscience, 2015, Aug-20, Volume: 301

    Topics: Animals; Chromatography, High Pressure Liquid; Chronic Disease; Disease Models, Animal; Electroencephalography; Epilepsy; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Microdialysis; Muscarinic Agonists; Pilocarpine; Rats; Rats, Sprague-Dawley; Scopolamine; Signal Transduction

2015
Disinhibition reduces extracellular glutamine and elevates extracellular glutamate in rat hippocampus in vivo.
    Epilepsy research, 2015, Volume: 114

    Topics: Action Potentials; Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Dendritic Cells; Electroencephalography; Epilepsy; Functional Laterality; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Glutamic Acid; Glutamine; Hippocampus; Male; Microdialysis; Organophosphorus Compounds; Pyridazines; Rats; Rats, Wistar; Sodium Channels

2015
Expression Patterns of TRPC1 in Cortical Lesions from Patients with Focal Cortical Dysplasia.
    Journal of molecular neuroscience : MN, 2015, Volume: 57, Issue:2

    Topics: Child; Child, Preschool; Epilepsy; Female; Glutamic Acid; Humans; Male; Malformations of Cortical Development, Group I; Neurons; RNA, Messenger; TRPC Cation Channels

2015
Thrombin decreases expression of the glutamate transporter GLAST and inhibits glutamate uptake in primary cortical astrocytes via the Rho kinase pathway.
    Experimental neurology, 2015, Volume: 273

    Topics: Adolescent; Animals; Animals, Newborn; Astrocytes; Blood-Brain Barrier; Cells, Cultured; Cerebral Cortex; Child; Child, Preschool; Epilepsy; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Female; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Male; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction; Thrombin; Time Factors; Young Adult; Zonula Occludens-1 Protein

2015
In vivo measurements of limbic glutamate and GABA concentrations in epileptic patients during affective and cognitive tasks: A microdialysis study.
    Hippocampus, 2016, Volume: 26, Issue:5

    Topics: Adult; Cognition; Electroencephalography; Emotions; Epilepsy; Female; Functional Laterality; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Limbic System; Microdialysis; Middle Aged; Photic Stimulation

2016
Microglia PACAP and glutamate: Friends or foes in seizure-induced autonomic dysfunction and SUDEP?
    Respiratory physiology & neurobiology, 2016, Volume: 226

    Topics: Animals; Autonomic Nervous System Diseases; Cardiovascular Diseases; Death, Sudden; Epilepsy; Glutamic Acid; Humans; Microglia; Neurons; Pituitary Adenylate Cyclase-Activating Polypeptide; Respiration; Seizures

2016
A New Computational Model for Neuro-Glio-Vascular Coupling: Astrocyte Activation Can Explain Cerebral Blood Flow Nonlinear Response to Interictal Events.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: Action Potentials; Algorithms; Animals; Astrocytes; Blood Vessels; Brain; Cerebrovascular Circulation; Computer Simulation; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Hemodynamics; Models, Biological; Neuroglia; Neurons; Neurotransmitter Agents; Rats

2016
Neurochemical modulation involved in the beneficial effect of liraglutide, GLP-1 agonist on PTZ kindling epilepsy-induced comorbidities in mice.
    Molecular and cellular biochemistry, 2016, Volume: 415, Issue:1-2

    Topics: Animals; Comorbidity; Epilepsy; gamma-Aminobutyric Acid; Glucagon-Like Peptide 1; Glutamic Acid; Glutathione; Kindling, Neurologic; Liraglutide; Male; Mice; Nitrites; Pentylenetetrazole

2016
Imaging increased glutamate in children with Sturge-Weber syndrome: Association with epilepsy severity.
    Epilepsy research, 2016, Volume: 122

    Topics: Aspartic Acid; Brain; Child; Child, Preschool; Creatine; Epilepsy; Female; Fluorodeoxyglucose F18; Follow-Up Studies; Glutamic Acid; Humans; Infant; Magnetic Resonance Imaging; Male; Multivariate Analysis; Positron-Emission Tomography; Proton Magnetic Resonance Spectroscopy; Radiopharmaceuticals; Regression Analysis; Severity of Illness Index; Sturge-Weber Syndrome

2016
The effect of butylphthalide on aminoacid content in the brain of epileptic mice.
    Minerva pediatrics, 2022, Volume: 74, Issue:6

    Topics: Amino Acids; Animals; Benzofurans; Brain; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Mice

2022
GABAergic Neuron-Specific Loss of Ube3a Causes Angelman Syndrome-Like EEG Abnormalities and Enhances Seizure Susceptibility.
    Neuron, 2016, Apr-06, Volume: 90, Issue:1

    Topics: Angelman Syndrome; Animals; Clathrin-Coated Vesicles; Electroencephalography; Epilepsy; GABAergic Neurons; Glutamic Acid; Mice; Neocortex; Neural Inhibition; Neurons; Presynaptic Terminals; Pyramidal Cells; Seizures; Ubiquitin-Protein Ligases

2016
Sonic hedgehog is a regulator of extracellular glutamate levels and epilepsy.
    EMBO reports, 2016, Volume: 17, Issue:5

    Topics: Animals; Calcium; Cerebral Cortex; Disease Models, Animal; Epilepsy; Extracellular Space; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gi-Go; Hedgehog Proteins; Hippocampus; Male; Mice; Mice, Knockout; Neurons; Pyramidal Cells; Rats; Signal Transduction; Zinc Finger Protein GLI1

2016
Evidence in support of using a neurochemistry approach to identify therapy for both epilepsy and associated depression.
    Epilepsy & behavior : E&B, 2016, Volume: 61

    Topics: Animals; Anticonvulsants; Brain; Depression; Depressive Disorder; Disease Models, Animal; Dopamine; Epilepsy; Glutamic Acid; Hindlimb Suspension; Kindling, Neurologic; Male; Mice; Neurochemistry; Norepinephrine; Pentylenetetrazole; Seizures; Serotonin; Treatment Outcome; Valproic Acid

2016
Expression pattern of NMDA receptors reveals antiepileptic potential of apigenin 8-C-glucoside and chlorogenic acid in pilocarpine induced epileptic mice.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 82

    Topics: Animals; Anticonvulsants; Antioxidants; Apigenin; Behavior, Animal; Chlorogenic Acid; Epilepsy; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamic Acid; Glutathione; Hippocampus; Male; Mice; Neuroprotective Agents; Nitric Oxide; Pilocarpine; Receptors, N-Methyl-D-Aspartate; Thiobarbituric Acid Reactive Substances

2016
Compromised GABAergic inhibition contributes to tumor-associated epilepsy.
    Epilepsy research, 2016, Volume: 126

    Topics: Animals; Brain; Brain Neoplasms; Bumetanide; Cell Line, Tumor; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Glioma; Glutamic Acid; K Cl- Cotransporters; Male; Mice, Inbred C57BL; Mice, Nude; Mice, Transgenic; Phosphorylation; Rats; Sodium Potassium Chloride Symporter Inhibitors; Solute Carrier Family 12, Member 2; Symporters; Tissue Culture Techniques

2016
Epileptic Phenotype of Two Siblings with Asparagine Synthesis Deficiency Mimics Neonatal Pyridoxine-Dependent Epilepsy.
    Neuropediatrics, 2016, Volume: 47, Issue:6

    Topics: Aspartate-Ammonia Ligase; Brain Diseases; Child, Preschool; Diagnosis; Epilepsy; Female; Glutamic Acid; Humans; Magnetic Resonance Imaging; Male; Metabolism, Inborn Errors; Siblings

2016
Glutamate concentrations vary with antiepileptic drug use and mental slowing.
    Epilepsy & behavior : E&B, 2016, Volume: 64, Issue:Pt A

    Topics: Adult; Anticonvulsants; Cognition; Cross-Sectional Studies; Epilepsy; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Occipital Lobe

2016
Participation of the dentate-rubral pathway in the kindling model of epilepsy.
    Journal of neuroscience research, 2017, Volume: 95, Issue:7

    Topics: Amygdala; Animals; Dentate Gyrus; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Kindling, Neurologic; Locomotion; Male; Neural Pathways; Rats; Rats, Wistar; Red Nucleus

2017
Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains.
    American journal of human genetics, 2016, Dec-01, Volume: 99, Issue:6

    Topics: Epilepsy; Exome; Glutamic Acid; Humans; Intellectual Disability; Models, Molecular; Mutation, Missense; Neurons; Protein Binding; Protein Domains; Protein Transport; Receptors, N-Methyl-D-Aspartate; Seizures

2016
Functional properties of granule cells with hilar basal dendrites in the epileptic dentate gyrus.
    Epilepsia, 2017, Volume: 58, Issue:1

    Topics: Action Potentials; Animals; Calcium; Dendrites; Dentate Gyrus; Disease Models, Animal; Epilepsy; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Male; Neurons; Patch-Clamp Techniques; Pyridazines; Rats; Rats, Wistar

2017
BRAF V600E mutation in epilepsy-associated glioneuronal tumors: Prevalence and correlation with clinical features in a Chinese population.
    Seizure, 2017, Volume: 45

    Topics: Adolescent; Adult; Brain; Brain Neoplasms; Child; Child, Preschool; China; Cohort Studies; Electroencephalography; Epilepsy; Female; Glioma; Glutamic Acid; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins B-raf; Statistics as Topic; Statistics, Nonparametric; Valine; Young Adult

2017
Pharmacologic inhibition of Hsp90 to prevent GLT-1 degradation as an effective therapy for epilepsy.
    The Journal of experimental medicine, 2017, Volume: 214, Issue:2

    Topics: Animals; Astrocytes; Benzoquinones; Cells, Cultured; Epilepsy; Epilepsy, Temporal Lobe; Excitatory Amino Acid Transporter 2; Glutamic Acid; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Proteasome Endopeptidase Complex; Seizures, Febrile

2017
Autoantibodies to NR2A Peptide of the Glutamate/NMDA Receptor in Patients with Seizure Disorders in Neuropsychiatric Systemic Lupus Erythematosus.
    Mediators of inflammation, 2017, Volume: 2017

    Topics: Adolescent; Adult; Antibodies; Autoantibodies; Case-Control Studies; Complement System Proteins; Epilepsy; Female; Glutamic Acid; Humans; Lupus Vasculitis, Central Nervous System; Male; Middle Aged; Peptides; Receptors, N-Methyl-D-Aspartate; Retrospective Studies; Young Adult

2017
P-gp Protein Expression and Transport Activity in Rodent Seizure Models and Human Epilepsy.
    Molecular pharmaceutics, 2017, 04-03, Volume: 14, Issue:4

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Capillaries; Carrier Proteins; Disease Models, Animal; Epilepsy; Female; Glutamic Acid; Humans; Rats; Rats, Wistar; Seizures; Up-Regulation

2017
Protective effect of spermine against pentylenetetrazole kindling epilepsy induced comorbidities in mice.
    Neuroscience research, 2017, Volume: 120

    Topics: Animals; Arginine; Avoidance Learning; Brain; Catecholamines; Comorbidity; Depression; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Kindling, Neurologic; Male; Mice; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Pentylenetetrazole; Spermine

2017
Effects of focal brain cooling on extracellular concentrations of neurotransmitters in patients with epilepsy.
    Epilepsia, 2017, Volume: 58, Issue:4

    Topics: Adolescent; Adult; Brain; Chi-Square Distribution; Child; Chromatography, High Pressure Liquid; Electrocorticography; Electroencephalography; Epilepsy; Extracellular Space; Female; Freezing; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Hypothermia, Induced; Male; Microdialysis; Middle Aged; Neurotransmitter Agents; Young Adult

2017
Altered functional efficacy of hippocampal interneuron during epileptogenesis following febrile seizures.
    Brain research bulletin, 2017, Volume: 131

    Topics: Animals; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; GABA Agents; GABA Antagonists; Glutamic Acid; Hippocampus; Interneurons; Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Seizures; Seizures, Febrile; Synaptic Transmission

2017
Pharmacologic analysis of the mechanism of dark neuron production in cerebral cortex.
    Acta neuropathologica, 2008, Volume: 116, Issue:4

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Artifacts; Biopsy; Brain Ischemia; Cerebral Cortex; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypoglycemia; Male; Neurons; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tetraethylammonium

2008
High resolution in situ zymography reveals matrix metalloproteinase activity at glutamatergic synapses.
    Neuroscience, 2009, Jan-12, Volume: 158, Issue:1

    Topics: Animals; Biological Assay; Brain; Epilepsy; Extracellular Matrix; Fluorescent Antibody Technique; Glutamic Acid; Male; Matrix Metalloproteinases; Microscopy, Fluorescence; Neurochemistry; Proteomics; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Tissue Embedding; Tissue Fixation

2009
Glutamate alteration of glutamic acid decarboxylase (GAD) in GABAergic neurons: the role of cysteine proteases.
    Experimental neurology, 2008, Volume: 213, Issue:1

    Topics: Animals; Brain Damage, Chronic; Calcium Signaling; Calpain; Cathepsins; Cells, Cultured; Cerebral Cortex; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Activation; Epilepsy; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Hypoxia-Ischemia, Brain; Mice; Mice, Inbred BALB C; Neurons; Neurotoxins; Receptors, N-Methyl-D-Aspartate

2008
Aldehyde fixation is not necessary for the formation of "dark" neurons.
    Acta neuropathologica, 2008, Volume: 116, Issue:4

    Topics: Aldehydes; Animals; Brain Ischemia; Epilepsy; Fixatives; Glutamic Acid; Humans; Hypoglycemia; Microscopy, Electron, Transmission; Neocortex; Neurons; Rats

2008
Impact of protein kinase C activation on epileptiform activity in the hippocampal slice.
    Epilepsy research, 2008, Volume: 82, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Action Potentials; Animals; Atropine; Benzoates; Benzophenanthridines; Enzyme Activation; Epilepsy; Glutamic Acid; Glycine; Guinea Pigs; Hippocampus; In Vitro Techniques; Neurotransmitter Agents; Phorbol 12,13-Dibutyrate; Picrotoxin; Protein Kinase C; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Signal Transduction

2008
Effect of infrared laser irradiation on amino acid neurotransmitters in an epileptic animal model induced by pilocarpine.
    Photomedicine and laser surgery, 2009, Volume: 27, Issue:3

    Topics: Alanine Transaminase; Amino Acids; Analysis of Variance; Animals; Aspartate Aminotransferases; Aspartic Acid; Cerebral Cortex; Chromatography, High Pressure Liquid; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Lasers, Semiconductor; Male; Models, Animal; Neurotransmitter Agents; Pilocarpine; Rats; Taurine

2009
Fgf-2 overexpression increases excitability and seizure susceptibility but decreases seizure-induced cell loss.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Dec-03, Volume: 28, Issue:49

    Topics: Animals; Cell Death; Convulsants; Disease Models, Animal; Epilepsy; Female; Fibroblast Growth Factor 2; Genetic Predisposition to Disease; Glutamic Acid; Growth Cones; Hippocampus; Humans; Male; Membrane Potentials; Mice; Mice, Transgenic; Nerve Degeneration; Neuronal Plasticity; Organ Culture Techniques; Patch-Clamp Techniques; Presynaptic Terminals; Pyramidal Cells; Synaptic Vesicles

2008
Astroglial metabolic networks sustain hippocampal synaptic transmission.
    Science (New York, N.Y.), 2008, Dec-05, Volume: 322, Issue:5907

    Topics: Animals; Astrocytes; Blood Glucose; Cell Membrane Permeability; Connexin 30; Connexin 43; Connexins; Diffusion; Epilepsy; Excitatory Postsynaptic Potentials; Gap Junctions; Glucose; Glutamic Acid; Hippocampus; In Vitro Techniques; Lactic Acid; Metabolic Networks and Pathways; Mice; Mice, Knockout; Mice, Transgenic; Neurons; Patch-Clamp Techniques; Receptors, AMPA; Synaptic Transmission

2008
Repeated 4-aminopyridine induced seizures diminish the efficacy of glutamatergic transmission in the neocortex.
    Experimental neurology, 2009, Volume: 219, Issue:1

    Topics: 4-Aminopyridine; Animals; Cobalt; Convulsants; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Neocortex; Organ Culture Techniques; Potassium Channel Blockers; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex; Synaptic Transmission

2009
The effects of group III mGluR ligands on pentylenetetrazol-induced kindling of seizures and hippocampal amino acids concentration.
    Brain research, 2009, Jul-28, Volume: 1282

    Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Kindling, Neurologic; Male; Pentylenetetrazole; Rats; Receptors, Metabotropic Glutamate; Taurine

2009
Prolonged exposure to WIN55,212-2 causes downregulation of the CB1 receptor and the development of tolerance to its anticonvulsant effects in the hippocampal neuronal culture model of acquired epilepsy.
    Neuropharmacology, 2009, Volume: 57, Issue:3

    Topics: Animals; Anticonvulsants; Benzoxazines; Cells, Cultured; Dose-Response Relationship, Drug; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Immunohistochemistry; Magnesium; Morpholines; Naphthalenes; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Pyramidal Cells; Rats; Receptor, Cannabinoid, CB1; Time Factors

2009
Pathological alterations in GABAergic interneurons and reduced tonic inhibition in the basolateral amygdala during epileptogenesis.
    Neuroscience, 2009, Sep-29, Volume: 163, Issue:1

    Topics: Amygdala; Animals; Convulsants; Down-Regulation; Epilepsy; Fluoresceins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Immunohistochemistry; Inhibitory Postsynaptic Potentials; Interneurons; Kainic Acid; Male; Nerve Degeneration; Neural Inhibition; Organic Chemicals; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Kainic Acid; Staining and Labeling; Status Epilepticus; Synaptic Transmission

2009
Transcriptome profiling reveals TGF-beta signaling involvement in epileptogenesis.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Jul-15, Volume: 29, Issue:28

    Topics: Action Potentials; Albumins; Animals; Antibodies; Astrocytes; Benzamides; Blood-Brain Barrier; Brain; Cluster Analysis; Dioxoles; Disease Models, Animal; Electric Stimulation; Epilepsy; gamma-Aminobutyric Acid; Gene Expression; Gene Expression Profiling; Gene Expression Regulation; Genome-Wide Association Study; Glutamic Acid; Immunoprecipitation; In Vitro Techniques; Inflammation; Ion Channels; Male; Microarray Analysis; Rats; Rats, Wistar; Signal Transduction; Smad2 Protein; Statistics, Nonparametric; Transforming Growth Factor beta; Transforming Growth Factor beta2

2009
Astrocytic dysfunction in epileptogenesis: consequence of altered potassium and glutamate homeostasis?
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Aug-26, Volume: 29, Issue:34

    Topics: Albumins; Animals; Astrocytes; Computer Simulation; Deoxycholic Acid; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamic Acid; In Vitro Techniques; Male; Models, Neurological; Neocortex; Oligonucleotide Array Sequence Analysis; Patch-Clamp Techniques; Potassium; Rats; Rats, Wistar

2009
Thyrotropin-releasing hormone d,l polylactide nanoparticles (TRH-NPs) protect against glutamate toxicity in vitro and kindling development in vivo.
    Brain research, 2009, Dec-15, Volume: 1303

    Topics: Administration, Intranasal; Amygdala; Animals; Biological Availability; Cells, Cultured; Drug Delivery Systems; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; Evoked Potentials; Glutamic Acid; Hippocampus; Kindling, Neurologic; Nanoparticles; Nerve Degeneration; Neuroprotective Agents; Polyesters; Rats; Rats, Sprague-Dawley; Thyrotropin-Releasing Hormone; Treatment Outcome

2009
Astrocyte-neuron interactions: implications for epilepsy.
    Neurology, 2009, Oct-20, Volume: 73, Issue:16

    Topics: Animals; Astrocytes; Blood Vessels; Brain; Epilepsy; Glutamic Acid; Homeostasis; Humans; Infant; Mice; Models, Neurological; Neurons; Potassium; Seizures; Synapses; Synaptic Transmission; Water

2009
Abnormal expressions of glutamate transporters and metabotropic glutamate receptor 1 in the spontaneously epileptic rat hippocampus.
    Brain research bulletin, 2010, Mar-16, Volume: 81, Issue:4-5

    Topics: Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Dentate Gyrus; Epilepsy; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hippocampus; Rats; Rats, Mutant Strains; Rats, Wistar; Receptors, Metabotropic Glutamate; RNA, Messenger

2010
Glutamate uptake shapes low-[Mg2+] induced epileptiform activity in juvenile rat hippocampal slices.
    Brain research, 2010, Jan-14, Volume: 1309

    Topics: Aging; Animals; Aspartic Acid; CA3 Region, Hippocampal; Dicarboxylic Acids; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Epilepsy; Glutamic Acid; Hippocampus; Kainic Acid; Magnesium; Magnesium Deficiency; Male; Neurons; Neurotransmitter Transport Proteins; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells; Pyrrolidines; Rats; Rats, Wistar; Synaptic Transmission

2010
Modulation of astrocyte glutamate transporters decreases seizures in a mouse model of Tuberous Sclerosis Complex.
    Neurobiology of disease, 2010, Volume: 37, Issue:3

    Topics: Animals; Astrocytes; Ceftriaxone; Cell Death; Disease Models, Animal; Down-Regulation; Epilepsy; Excitatory Amino Acid Transporter 2; Extracellular Fluid; Glial Fibrillary Acidic Protein; Glutamic Acid; Mice; Mice, Knockout; Survival Rate; Tuberous Sclerosis; Tuberous Sclerosis Complex 1 Protein; Tumor Suppressor Proteins; Up-Regulation

2010
Regionally localized recurrent excitation in the dentate gyrus of a cortical contusion model of posttraumatic epilepsy.
    Journal of neurophysiology, 2010, Volume: 103, Issue:3

    Topics: Animals; Brain Injuries; Contusions; Data Interpretation, Statistical; Dentate Gyrus; Electrophysiology; Epilepsy; Excitatory Postsynaptic Potentials; Glutamic Acid; Immunohistochemistry; In Vitro Techniques; Male; Membrane Potentials; Mice; Mossy Fibers, Hippocampal; Patch-Clamp Techniques; Photic Stimulation; Synapses

2010
Glutamine is required for persistent epileptiform activity in the disinhibited neocortical brain slice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Jan-27, Volume: 30, Issue:4

    Topics: Action Potentials; Animals; Carrier Proteins; Epilepsy; Glutamic Acid; Glutamine; Neocortex; Nerve Net; Neural Inhibition; Neural Pathways; Neurons; Organ Culture Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Synaptic Transmission

2010
On the role of glutamic acid in epilepsy.
    Federation proceedings, 1947, Volume: 6, Issue:1 Pt 2

    Topics: Epilepsy; Glutamates; Glutamic Acid; Humans

1947
Neuroprotective effect of piperine on primarily cultured hippocampal neurons.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:4

    Topics: Alkaloids; Animals; Anticonvulsants; Apoptosis; Benzodioxoles; Calcium; Calcium Signaling; Cell Survival; Drugs, Chinese Herbal; Epilepsy; Glutamic Acid; Hippocampus; Neurons; Neuroprotective Agents; Piper nigrum; Piperidines; Polyunsaturated Alkamides; Rats; Signal Transduction; Synapses; Synaptic Transmission

2010
Dihydropyrimidinone positive modulation of delta-subunit-containing gamma-aminobutyric acid type A receptors, including an epilepsy-linked mutant variant.
    Biochemistry, 2010, Jun-15, Volume: 49, Issue:23

    Topics: Alanine; Allosteric Regulation; Cell Line; Drug Synergism; Epilepsy; Genetic Variation; Glutamic Acid; Humans; Mutagenesis, Site-Directed; Protein Binding; Protein Isoforms; Protein Subunits; Pyrimidines; Pyrimidinones; Receptors, GABA-A; Thiones

2010
Distinct FGFs promote differentiation of excitatory and inhibitory synapses.
    Nature, 2010, Jun-10, Volume: 465, Issue:7299

    Topics: Animals; Cell Differentiation; Cells, Cultured; Dendrites; Disease Susceptibility; Epilepsy; Excitatory Postsynaptic Potentials; Fibroblast Growth Factor 7; Fibroblast Growth Factors; gamma-Aminobutyric Acid; Gene Expression Profiling; Glutamic Acid; Hippocampus; In Situ Hybridization; Inhibitory Postsynaptic Potentials; Kindling, Neurologic; Mice; Mice, Knockout; Miniature Postsynaptic Potentials; Presynaptic Terminals; Pyramidal Cells; Receptors, Fibroblast Growth Factor; Seizures; Synapses; Synaptic Transmission; Synaptic Vesicles

2010
[Effect of Chaihu Shugan Tang on excitability in different brain regions of pentylenetetrazole-kindled chronic epileptic rats].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2010, Volume: 35, Issue:12

    Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Aspartic Acid; Brain; Chronic Disease; Deoxyglucose; Disease Models, Animal; Drugs, Chinese Herbal; Epilepsy; Glutamic Acid; Hippocampus; Humans; Kindling, Neurologic; Male; Pentylenetetrazole; Random Allocation; Rats; Valproic Acid

2010
Effects of 1 (-) glutamic acid and other agents on experimental seizures.
    Archives of neurology and psychiatry, 1946, Volume: 56, Issue:1

    Topics: Epilepsy; Glutamic Acid; Humans; Seizures

1946
Glutamate clearance mechanisms in resected cortical dysplasia.
    Journal of neurosurgery, 2011, Volume: 114, Issue:4

    Topics: Adolescent; Adult; Amino Acid Transport System X-AG; Child; Electroencephalography; Epilepsy; Excitatory Amino Acid Transporter 2; Female; Fluorescent Antibody Technique, Indirect; Glial Fibrillary Acidic Protein; Glutamate Plasma Membrane Transport Proteins; Glutamate-Ammonia Ligase; Glutamic Acid; Humans; Immunohistochemistry; Male; Malformations of Cortical Development; Monitoring, Intraoperative; Neocortex; Neuroglia; Neurons; Neurosurgical Procedures; Young Adult

2011
An organotypic hippocampal slice culture model of excitotoxic injury induced spontaneous recurrent epileptiform discharges.
    Brain research, 2011, Jan-31, Volume: 1371

    Topics: Action Potentials; Animals; Anticonvulsants; Cell Survival; Epilepsy; Ethosuximide; Glutamic Acid; Hippocampus; Nerve Net; Neurons; Neurotoxins; Organ Culture Techniques; Patch-Clamp Techniques; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Stroke

2011
mRNA for the EAAC1 subtype of glutamate transporter is present in neuronal dendrites in vitro and dramatically increases in vivo after a seizure.
    Neurochemistry international, 2011, Volume: 58, Issue:3

    Topics: Animals; Cell Polarity; Cells, Cultured; Dendrites; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Transporter 3; Glutamic Acid; Rats; Rats, Sprague-Dawley; RNA, Messenger; Up-Regulation

2011
New insights on culture and calcium signalling in neurons and astrocytes from epileptic patients.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2011, Volume: 29, Issue:2

    Topics: Adult; Astrocytes; Calcium; Calcium Signaling; Cell Culture Techniques; Cells, Cultured; Epilepsy; Female; Glutamic Acid; Humans; Male; Middle Aged; Neurons; Young Adult

2011
Study of epileptiform activity in cerebral ganglion of mud crab Scylla serrata.
    Invertebrate neuroscience : IN, 2011, Volume: 11, Issue:1

    Topics: Animals; Anticonvulsants; Brachyura; Convulsants; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Glutamic Acid; Neurons; Pentylenetetrazole; Valproic Acid

2011
[The effect of high frequency stimulation of epileptic foci on the release of glutamate and gamma-aminobutyric acid in hippocampus of the kainic acid-kindled rats].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2011, Volume: 27, Issue:1

    Topics: Animals; Electric Stimulation; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Kainic Acid; Kindling, Neurologic; Male; Rats; Rats, Sprague-Dawley

2011
High frequency stimulation abolishes thalamic network oscillations: an electrophysiological and computational analysis.
    Journal of neural engineering, 2011, Volume: 8, Issue:4

    Topics: Action Potentials; Algorithms; Animals; Biosensing Techniques; Cerebral Cortex; Computer Simulation; Cyclic Nucleotide-Gated Cation Channels; Deep Brain Stimulation; Electrophysiological Phenomena; Epilepsy; Female; Ferrets; Glutamic Acid; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Interneurons; Membrane Potentials; Models, Neurological; Nerve Net; Potassium Channels; Thalamus

2011
Vinpocetine inhibits glutamate release induced by the convulsive agent 4-aminopyridine more potently than several antiepileptic drugs.
    Epilepsy research, 2011, Volume: 96, Issue:3

    Topics: 4-Aminopyridine; Animals; Anticonvulsants; Calcium; Carbamazepine; Drug Interactions; Epilepsy; Fructose; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Lamotrigine; Male; Nerve Endings; Oxcarbazepine; Phenytoin; Potassium Channel Blockers; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Tetrodotoxin; Topiramate; Triazines; Tritium; Vinca Alkaloids

2011
Glutamate release by primary brain tumors induces epileptic activity.
    Nature medicine, 2011, Sep-11, Volume: 17, Issue:10

    Topics: Amino Acid Transport System y+; Analysis of Variance; Animals; Brain Neoplasms; Cell Transplantation; Electroencephalography; Electrophysiology; Epilepsy; Glioma; Glutamic Acid; Humans; Mice; Mice, SCID; Sulfasalazine

2011
Ketogenic diet-induced peroxisome proliferator-activated receptor-γ activation decreases neuroinflammation in the mouse hippocampus after kainic acid-induced seizures.
    Experimental neurology, 2011, Volume: 232, Issue:2

    Topics: Acetoacetates; Animals; Body Weight; CD11b Antigen; Cell Line; Cell Survival; Cyclooxygenase 2; Diet, Ketogenic; Encephalitis; Epilepsy; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Kainic Acid; Male; Mice; Mice, Inbred ICR; Neurons; PPAR gamma; Tumor Necrosis Factor-alpha

2011
Glioma-related seizures: glutamate is the key.
    Nature medicine, 2011, Oct-11, Volume: 17, Issue:10

    Topics: Animals; Brain Neoplasms; Epilepsy; Glioma; Glutamic Acid; Humans

2011
Glutamate and tumor-associated epilepsy.
    Oncotarget, 2011, Volume: 2, Issue:11

    Topics: Animals; Brain Neoplasms; Epilepsy; Glutamic Acid; Humans

2011
Increased cholecystokinin labeling in the hippocampus of a mouse model of epilepsy maps to spines and glutamatergic terminals.
    Neuroscience, 2012, Jan-27, Volume: 202

    Topics: Animals; CA1 Region, Hippocampal; Cholecystokinin; Dendritic Spines; Epilepsy; Excitatory Postsynaptic Potentials; Fluorescent Antibody Technique; Glutamic Acid; Hippocampus; Immunoenzyme Techniques; Immunohistochemistry; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Microscopy, Electron; Pilocarpine; Presynaptic Terminals; Receptor, Cannabinoid, CB1; Scopolamine

2012
Reduction of vesicle-associated membrane protein 2 expression leads to a kindling-resistant phenotype in a murine model of epilepsy.
    Neuroscience, 2012, Jan-27, Volume: 202

    Topics: Animals; CA1 Region, Hippocampal; CA2 Region, Hippocampal; Data Interpretation, Statistical; Dentate Gyrus; Electric Stimulation; Epilepsy; Glutamic Acid; Kindling, Neurologic; Mice; Mice, Inbred C57BL; Mice, Knockout; Microelectrodes; SNARE Proteins; Vesicle-Associated Membrane Protein 2

2012
Activation of group III metabotropic glutamate receptors by endogenous glutamate protects against glutamate-mediated excitotoxicity in the hippocampus in vivo.
    Journal of neuroscience research, 2012, Volume: 90, Issue:5

    Topics: 4-Aminopyridine; Amino Acids; Animals; Carboxylic Acids; Chromatography, High Pressure Liquid; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electrochemistry; Electroencephalography; Epilepsy; Excitatory Amino Acid Antagonists; Extracellular Fluid; Glutamic Acid; Hippocampus; Male; Microdialysis; Phosphoserine; Potassium Channel Blockers; Pyridines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Time Factors

2012
Calcium/calmodulin-dependent protein kinase II (CaMKII) inhibition induces neurotoxicity via dysregulation of glutamate/calcium signaling and hyperexcitability.
    The Journal of biological chemistry, 2012, Mar-09, Volume: 287, Issue:11

    Topics: Action Potentials; Animals; Brain Injuries; Brain Ischemia; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Caspase 3; Cell Death; Cells, Cultured; Cycloheximide; Epilepsy; Glutamic Acid; Nerve Tissue Proteins; Neurons; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

2012
Glutamate transporters control metabotropic glutamate receptors activation to prevent the genesis of paroxysmal burst in the developing hippocampus.
    Neuroscience, 2012, Apr-05, Volume: 207

    Topics: Animals; Animals, Newborn; Epilepsy; Epilepsy, Temporal Lobe; Female; Glutamic Acid; Hippocampus; Male; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synaptic Transmission; Vesicular Glutamate Transport Proteins

2012
Astrocytes convert network excitation to tonic inhibition of neurons.
    BMC biology, 2012, Mar-15, Volume: 10

    Topics: Animals; Astrocytes; Disease Models, Animal; Epilepsy; Feedback, Physiological; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hippocampus; Humans; Neural Inhibition; Rats; Rats, Wistar; Synaptic Transmission

2012
In vitro mechanical strain trauma alters neuronal calcium responses: Implications for posttraumatic epilepsy.
    Epilepsia, 2012, Volume: 53 Suppl 1

    Topics: Animals; Astrocytes; Brain Injuries; Calcium; Calcium Signaling; Cell Count; Cell Death; Cells, Cultured; Epilepsy; Excitatory Amino Acids; Female; Glutamic Acid; Intracellular Space; Male; Neurons; Rats; Stress, Mechanical

2012
A 9-year follow-up of a girl with pyridoxine (vitamin B6)-dependent seizures: magnetic resonance spectroscopy findings.
    European review for medical and pharmacological sciences, 2012, Volume: 16, Issue:5

    Topics: Adolescent; Anticonvulsants; Aspartic Acid; Biomarkers; Brain; Child; Creatinine; Disease Progression; Epilepsy; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Predictive Value of Tests; Pyridoxine; Treatment Outcome; Vitamin B Complex

2012
A study of epileptogenic network structures in rat hippocampal cultures using first spike latencies during synchronization events.
    Physical biology, 2012, Volume: 9, Issue:5

    Topics: Animals; Cells, Cultured; Disease Models, Animal; Electrophysiological Phenomena; Epilepsy; Glutamic Acid; Hippocampus; Nerve Net; Neurons; Rats; Rats, Wistar

2012
ONO-2506 inhibits spike-wave discharges in a genetic animal model without affecting traditional convulsive tests via gliotransmission regulation.
    British journal of pharmacology, 2013, Volume: 168, Issue:5

    Topics: Animals; Anticonvulsants; Astrocytes; Caprylates; Cells, Cultured; Convulsants; Disease Models, Animal; Electroshock; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Kynurenic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pentylenetetrazole; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Serine; Synaptic Transmission

2013
Rapid compensatory changes in the expression of EAAT-3 and GAT-1 transporters during seizures in cells of the CA1 and dentate gyrus.
    Journal of biomedical science, 2012, Aug-29, Volume: 19

    Topics: 4-Aminopyridine; Animals; Behavior, Animal; CA1 Region, Hippocampal; Catheters; Dentate Gyrus; Electroencephalography; Epilepsy; Excitatory Amino Acid Transporter 3; GABA Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Male; Rats; Rats, Wistar; Seizures

2012
Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability.
    Neuron, 2012, Sep-20, Volume: 75, Issue:6

    Topics: 3' Untranslated Regions; Animals; Animals, Newborn; Brain; Computational Biology; Disease Models, Animal; ELAV Proteins; Electroencephalography; Epilepsy; Gene Expression Regulation; Glutamic Acid; Glutaminase; Mice; Mice, Knockout; Microarray Analysis; Nerve Tissue Proteins; Neurons; RNA Splicing; RNA-Binding Proteins; RNA, Messenger

2012
Subventricular zone neural progenitors protect striatal neurons from glutamatergic excitotoxicity.
    Brain : a journal of neurology, 2012, Volume: 135, Issue:Pt 11

    Topics: 4-Aminopyridine; Amidohydrolases; Animals; Arachidonic Acids; Benzamides; Carbamates; Corpus Striatum; Disease Models, Animal; Dronabinol; Endocannabinoids; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Ganciclovir; Glutamic Acid; Lateral Ventricles; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Stem Cells; Neuroprotective Agents; Polyunsaturated Alkamides; Stem Cells; Stroke

2012
Protective role of astrocytic leptin signaling against excitotoxicity.
    Journal of molecular neuroscience : MN, 2013, Volume: 49, Issue:3

    Topics: Animals; Astrocytes; Astrocytoma; Cell Line, Tumor; Convulsants; Epilepsy; Female; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Gliosis; Glutamic Acid; Hippocampus; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Neurotoxins; Pilocarpine; Receptors, Leptin; Recurrence; Signal Transduction; Up-Regulation

2013
Comparison and effects of acute lamotrigine treatment on extracellular excitatory amino acids in the hippocampus of PTZ-kindled epileptic and PTZ-induced status epilepticus rats.
    Neurochemical research, 2013, Volume: 38, Issue:3

    Topics: Animals; Aspartic Acid; Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kindling, Neurologic; Lamotrigine; Male; Neurotransmitter Agents; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Status Epilepticus; Triazines

2013
[Mechanism in diminishing dendritic spines following excessive nerve excitation].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2012, Volume: 140, Issue:3

    Topics: Brain; Cadherins; Dendritic Spines; Drug Design; Endocytosis; Epilepsy; Glutamic Acid; Humans; Imidazoles; Memory Disorders; p38 Mitogen-Activated Protein Kinases; Protein Binding; Protein Kinases; Protocadherins; Pyridines; Synapses

2012
Higher glutamate to glutamine ratios in occipital regions in women with migraine during the interictal state.
    Headache, 2013, Volume: 53, Issue:2

    Topics: Adult; Analysis of Variance; Aspartic Acid; Case-Control Studies; Epilepsy; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Migraine Disorders; Occipital Lobe; Young Adult

2013
[Changes of glutamate and γ-aminobutyric acid of extracellular fluid in hippocampus during electrical stimulation of anterior nucleus thalamus in rats].
    Zhonghua yi xue za zhi, 2012, Dec-18, Volume: 92, Issue:47

    Topics: Animals; Anterior Thalamic Nuclei; Disease Models, Animal; Electric Stimulation; Epilepsy; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Rats; Rats, Sprague-Dawley

2012
A neuronal glutamate transporter contributes to neurotransmitter GABA synthesis and epilepsy.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Aug-01, Volume: 22, Issue:15

    Topics: Action Potentials; Amino Acid Transport System X-AG; Animals; Behavior, Animal; Carbon Radioisotopes; Carrier Proteins; Electroencephalography; Entorhinal Cortex; Epilepsy; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; gamma-Aminobutyric Acid; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hippocampus; In Vitro Techniques; Injections, Intraventricular; Male; Neurons; Oligonucleotides, Antisense; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Symporters; Thalamus; Video Recording

2002
Valproate-induced encephalopathy: assessment with MR imaging and 1H MR spectroscopy.
    Epilepsia, 2002, Volume: 43, Issue:9

    Topics: Adult; Anticonvulsants; Aspartic Acid; Brain; Brain Diseases, Metabolic; Choline; Creatine; Epilepsy; Glutamic Acid; Glutamine; Humans; Hyperammonemia; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Occipital Lobe; Valproic Acid

2002
Expression of glutamate transporters and ionotropic glutamate receptors in GLAST knockout mice.
    Brain research. Molecular brain research, 2002, Aug-15, Volume: 104, Issue:2

    Topics: Amino Acid Transport System X-AG; Animals; Down-Regulation; Epilepsy; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Female; Frontal Lobe; Genetic Predisposition to Disease; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Symporters; Synaptic Transmission

2002
Protective effect of the antiepileptic drug candidate talampanel against AMPA-induced striatal neurotoxicity in neonatal rats.
    Brain research bulletin, 2002, Oct-15, Volume: 59, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Anti-Anxiety Agents; Asphyxia Neonatorum; Behavior, Animal; Benzodiazepines; Cell Death; Epilepsy; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Male; Movement Disorders; Neostriatum; Neuroprotective Agents; Neurotoxins; Rats; Receptors, AMPA; Synaptic Transmission

2002
Calcium-dependent epileptogenesis in an in vitro model of stroke-induced "epilepsy".
    Epilepsia, 2002, Volume: 43, Issue:11

    Topics: Animals; Calcium; Cells, Cultured; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Intracellular Membranes; Neurons; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Stroke; Time Factors

2002
Relation between responsiveness to neurotransmitters and complexity of epileptiform activity in rat hippocampal CA1 neurons.
    Epilepsia, 2002, Volume: 43, Issue:11

    Topics: Action Potentials; Animals; Entropy; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Neurons; Penicillins; Rats; Rats, Sprague-Dawley

2002
Block of glutamate-glutamine cycle between astrocytes and neurons inhibits epileptiform activity in hippocampus.
    Journal of neurophysiology, 2002, Volume: 88, Issue:5

    Topics: Animals; Astrocytes; Cells, Cultured; Electrophysiology; Epilepsy; Extracellular Space; Fluorescent Dyes; Fura-2; GABA Antagonists; Glutamic Acid; Glutamine; Hippocampus; Membrane Potentials; Microscopy, Video; Neuroglia; Neurons; Patch-Clamp Techniques; Rats

2002
Differences in ionotropic glutamate receptor subunit expression are not responsible for strain-dependent susceptibility to excitotoxin-induced injury.
    Brain research. Molecular brain research, 2003, Apr-10, Volume: 112, Issue:1-2

    Topics: Animals; Cell Death; Disease Models, Animal; Drug Resistance; Epilepsy; Genetic Predisposition to Disease; Glutamic Acid; Immunohistochemistry; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurotoxins; Protein Subunits; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Species Specificity; Synaptic Transmission

2003
Automated data processing of [1H-decoupled] 13C MR spectra acquired from human brain in vivo.
    Journal of magnetic resonance (San Diego, Calif. : 1997), 2003, Volume: 162, Issue:2

    Topics: Brain; Carbon Isotopes; Electronic Data Processing; Epilepsy; Glucose; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Mathematical Computing; Observer Variation

2003
Extracellular concentrations of catecholamines and amino acids in the dorsomedial hypothalamus of kindled rats. A microdialysis study.
    Pharmacology, 2003, Volume: 68, Issue:4

    Topics: Animals; Bicuculline; Blood Pressure; Chromatography, High Pressure Liquid; Dopamine; Dorsomedial Hypothalamic Nucleus; Epilepsy; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Heart Rate; Kindling, Neurologic; Male; Microdialysis; N-Methylaspartate; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

2003
Translocation of glutamate transporter subtype excitatory amino acid carrier 1 protein in kainic acid-induced rat epilepsy.
    The American journal of pathology, 2003, Volume: 163, Issue:2

    Topics: Amino Acid Transport System X-AG; Animals; Cell Line; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Kainic Acid; Male; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Symporters

2003
Impaired glial glutamate transport in a mouse tuberous sclerosis epilepsy model.
    Annals of neurology, 2003, Volume: 54, Issue:2

    Topics: Animals; Astrocytes; Biological Transport, Active; Blotting, Western; Cells, Cultured; Electrophysiology; Epilepsy; Gliosis; Glutamic Acid; Homeostasis; Mice; Mice, Knockout; Neuroglia; Proteins; RNA, Messenger; Synapses; Tuberous Sclerosis; Tuberous Sclerosis Complex 1 Protein; Tumor Suppressor Proteins

2003
GluR2(B) knockdown accelerates CA3 injury after kainate seizures.
    Journal of neuropathology and experimental neurology, 2003, Volume: 62, Issue:7

    Topics: Animals; Calcium Signaling; Cell Death; Epilepsy; Glutamic Acid; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Nerve Degeneration; Neurons; Neurotoxins; Oligonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Status Epilepticus

2003
Expression of heat shock protein 70 induced by 4-aminopyridine through glutamate-mediated excitotoxic stress in rat hippocampus in vivo.
    Neuropharmacology, 2003, Volume: 45, Issue:5

    Topics: 4-Aminopyridine; Animals; Anticonvulsants; Cell Count; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Drug Interactions; Electroencephalography; Epilepsy; Extracellular Space; Functional Laterality; Gene Expression; Glutamic Acid; Hippocampus; HSP70 Heat-Shock Proteins; Immunohistochemistry; Male; Microdialysis; Nerve Degeneration; Neuroprotective Agents; Piperazines; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Somatosensory Cortex; Stress, Physiological; Time Factors

2003
Amino acid composition of brain cysts: levels of excitatory amino acids in cyst fluid fail to predict seizures.
    Epilepsy research, 2003, Volume: 55, Issue:3

    Topics: Adenosine; Adolescent; Adult; Anticonvulsants; Aspartic Acid; Brain; Child; Cysts; Electroencephalography; Epilepsy; Excitatory Amino Acids; Female; Glutamic Acid; Humans; Male; Middle Aged; Time Factors

2003
[Therapeutic use of magnesium glutamate in epilepsy and mental deficiency].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1954, Nov-30, Volume: 30, Issue:75

    Topics: Diet, Reducing; Epilepsy; Glutamates; Glutamic Acid; Intellectual Disability; Magnesium

1954
Therapeutic experiments with glutamic acid in child psychiatry.
    Therapia Hungarica (English edition), 1954, Volume: 4

    Topics: Child; Child Psychiatry; Diet, Reducing; Epilepsy; Glutamates; Glutamic Acid; Humans; Intellectual Disability

1954
[Treatment of epilepsy with glutamic acid].
    Polski tygodnik lekarski, 1955, Dec-12, Volume: 10, Issue:50

    Topics: Epilepsy; Glutamates; Glutamic Acid

1955
Glutamic acid and gamma-aminobutyric acid in seizures.
    Clinica chimica acta; international journal of clinical chemistry, 1957, Volume: 2, Issue:5

    Topics: Amino Acids; Cerebral Cortex; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Seizures

1957
[Magnesium glutamate and epileptic sequelae of lobotomy].
    Revue medicale de Nancy, 1961, Volume: 86

    Topics: Epilepsy; Glutamates; Glutamic Acid; Humans; Magnesium; Psychosurgery

1961
[Treatment of epilepsy with glutamic acid].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1955, Volume: 55, Issue:5

    Topics: Epilepsy; Glutamates; Glutamic Acid

1955
In vitro formation of a secondary epileptogenic mirror focus by interhippocampal propagation of seizures.
    Nature neuroscience, 2003, Volume: 6, Issue:10

    Topics: Animals; Animals, Newborn; Chloride Channels; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Functional Laterality; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Kainic Acid; Male; Membrane Potentials; Neural Pathways; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission

2003
Neuroscience. Stout guards of the central nervous system.
    Science (New York, N.Y.), 2003, Oct-03, Volume: 302, Issue:5642

    Topics: Animals; Anticonvulsants; Arachidonic Acids; Brain; Brain Diseases; Cannabidiol; Cannabinoid Receptor Modulators; Cannabinoids; Convulsants; Dronabinol; Endocannabinoids; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycerides; Humans; Kainic Acid; Mice; Neurons; Neuroprotective Agents; Polyunsaturated Alkamides; Rats; Receptors, Cannabinoid; Receptors, Drug; Signal Transduction

2003
CB1 cannabinoid receptors and on-demand defense against excitotoxicity.
    Science (New York, N.Y.), 2003, Oct-03, Volume: 302, Issue:5642

    Topics: Animals; Arachidonic Acids; Brain; Brain-Derived Neurotrophic Factor; Cannabinoids; Endocannabinoids; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Furans; gamma-Aminobutyric Acid; Gene Expression Regulation; Genes, Immediate-Early; Glutamic Acid; Glycerides; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mitogen-Activated Protein Kinases; Mutation; Neurons; Neuroprotective Agents; Piperidines; Polyunsaturated Alkamides; Prosencephalon; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Signal Transduction

2003
Epilepsy, neurodegeneration, and extracellular glutamate in the hippocampus of awake and anesthetized rats treated with okadaic acid.
    Neurochemical research, 2003, Volume: 28, Issue:10

    Topics: Anesthetics, Inhalation; Animals; Electroencephalography; Epilepsy; Extracellular Fluid; Glutamic Acid; Halothane; Hippocampus; Male; Microdialysis; Nerve Degeneration; Okadaic Acid; Phosphoprotein Phosphatases; Rats; Rats, Wistar; Wakefulness

2003
Long-lasting alterations in neuronal calcium homeostasis in an in vitro model of stroke-induced epilepsy.
    Cell calcium, 2004, Volume: 35, Issue:2

    Topics: Animals; Calcium; Cells, Cultured; Epilepsy; Glutamic Acid; Hippocampus; Homeostasis; Neurons; Rats; Rats, Sprague-Dawley; Stroke; Time

2004
[Glutamic acid and hyperglutinate diet in neuropsychiatry].
    Rivista di patologia nervosa e mentale, 1951, Volume: 72, Issue:1

    Topics: Diet; Epilepsy; Glutamic Acid; Humans; Neuropsychiatry

1951
Glutamic acid and its salts in petit mal epilepsy.
    The Journal of mental science, 1951, Volume: 97, Issue:409

    Topics: Epilepsy; Epilepsy, Absence; Glutamates; Glutamic Acid; Salts

1951
Mitochondrial oxidative stress and increased seizure susceptibility in Sod2(-/+) mice.
    Free radical biology & medicine, 2004, Mar-01, Volume: 36, Issue:5

    Topics: Aconitate Hydratase; Amino Acid Transport System X-AG; Animals; Deoxyadenosines; Epilepsy; Excitatory Amino Acid Transporter 2; Glutamic Acid; Kainic Acid; Mice; Mice, Knockout; Mitochondria; Neurodegenerative Diseases; Neurotoxins; Oxidative Stress; Oxygen; Seizures; Superoxide Dismutase; Superoxides

2004
[Hyperexcitability CA1 neurons induced by brief episodes of hypoxia in hippocampal slices in rats of various age groups].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2004, Volume: 90, Issue:1

    Topics: Action Potentials; Aging; Animals; Cell Hypoxia; Electric Stimulation; Epilepsy; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Kindling, Neurologic; Male; Neurons; Pyramidal Cells; Rats; Synaptic Transmission

2004
Nefopam blocks voltage-sensitive sodium channels and modulates glutamatergic transmission in rodents.
    Brain research, 2004, Jul-09, Volume: 1013, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Non-Narcotic; Animals; Binding, Competitive; Electroshock; Epilepsy; Excitatory Amino Acid Agonists; Glutamic Acid; Ion Channel Gating; Kainic Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Nefopam; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Sodium Channels; Synaptic Transmission; Tritium

2004
Quinolinic acid promotes seizures and decreases glutamate uptake in young rats: reversal by orally administered guanosine.
    Brain research, 2004, Aug-20, Volume: 1018, Issue:1

    Topics: Administration, Oral; Aging; Animals; Animals, Newborn; Anticonvulsants; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Drug Interactions; Epilepsy; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Glutamic Acid; Guanosine; In Vitro Techniques; Injections, Intraventricular; Male; Neurons; Phenobarbital; Picrotoxin; Quinolinic Acid; Rats; Rats, Wistar

2004
Seizure evolution and amino acid imbalances in murine succinate semialdehyde dehydrogenase (SSADH) deficiency.
    Neurobiology of disease, 2004, Volume: 16, Issue:3

    Topics: Aldehyde Oxidoreductases; Amino Acids; Animals; Brain; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Inhibition; Succinate-Semialdehyde Dehydrogenase

2004
[Medicinal therapy of convulsive nervous diseases].
    Das Deutsche Gesundheitswesen, 1950, Jul-06, Volume: 5, Issue:27

    Topics: Epilepsy; Glutamic Acid; Humans; Nervous System Diseases; Neurology; Seizures

1950
[Changes of amino acid content in hippocampus of epileptic rats treated with volatile oil of Acorus tatarinowii].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2004, Volume: 29, Issue:7

    Topics: Acorus; Animals; Anticonvulsants; Aspartic Acid; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Kainic Acid; Male; Oils, Volatile; Plants, Medicinal; Rats; Rats, Sprague-Dawley

2004
Meditation may predispose to epilepsy: an insight into the alteration in brain environment induced by meditation.
    Medical hypotheses, 2005, Volume: 64, Issue:3

    Topics: Alpha Rhythm; Autonomic Nervous System; Brain; Brain Chemistry; Diagnostic Imaging; Epilepsy; Glutamic Acid; Gyrus Cinguli; Humans; Meditation; Neurotransmitter Agents; Prefrontal Cortex; Serotonin; Ultrasonography

2005
In vitro 1H NMR spectroscopy shows an increase in N-acetylaspartylglutamate and glutamine content in the hippocampus of amygdaloid-kindled rats.
    Journal of neurochemistry, 2005, Volume: 92, Issue:6

    Topics: Amino Acids; Amygdala; Animals; Creatine; Dipeptides; Disease Models, Animal; Energy Metabolism; Epilepsy; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Glycine; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Magnetic Resonance Spectroscopy; Male; Neural Pathways; Rats; Rats, Wistar; Up-Regulation

2005
Up-regulation of neuropeptide Y levels and modulation of glutamate release through neuropeptide Y receptors in the hippocampus of kainate-induced epileptic rats.
    Journal of neurochemistry, 2005, Volume: 93, Issue:1

    Topics: Animals; Disease Models, Animal; Drug Interactions; Epilepsy; Glutamic Acid; Hippocampus; Kainic Acid; Male; Neuropeptide Y; Peptide Fragments; Potassium Chloride; Rats; Rats, Wistar; Receptors, Neuropeptide Y; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Up-Regulation

2005
Convulsant activity and neurochemical alterations induced by a fraction obtained from fruit Averrhoa carambola (Oxalidaceae: Geraniales).
    Neurochemistry international, 2005, Volume: 46, Issue:7

    Topics: Animals; Binding, Competitive; Brain; Brain Chemistry; Convulsants; Epilepsy; Fruit; gamma-Aminobutyric Acid; Glutamic Acid; Magnoliopsida; Male; Mice; Molecular Weight; Neurons; Neurotoxins; Plant Extracts; Presynaptic Terminals; Radioligand Assay; Rats; Rats, Wistar; Synaptic Transmission

2005
In vivo modulatory action of extracellular glutamate on the anticonvulsant effects of hippocampal dopamine and serotonin.
    Epilepsia, 2005, Volume: 46, Issue:6

    Topics: Animals; Anticonvulsants; Convulsants; Dopamine; Dopamine Antagonists; Epilepsy; Glutamic Acid; Hippocampus; Limbic System; Male; Microdialysis; Pilocarpine; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Serotonin; Serotonin

2005
Detection of increased local excitatory circuits in the hippocampus during epileptogenesis using focal flash photolysis of caged glutamate.
    Epilepsia, 2005, Volume: 46 Suppl 5

    Topics: Animals; Dentate Gyrus; Disease Models, Animal; Epilepsy; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Kainic Acid; Male; Models, Neurological; Mossy Fibers, Hippocampal; Neural Pathways; Patch-Clamp Techniques; Photolysis; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Status Epilepticus; Synaptic Transmission

2005
Seizures induced by microperfusion of glutamate and glycine in the hippocampus of rats pretreated with latrunculin A.
    Neuroscience letters, 2005, Nov-11, Volume: 388, Issue:2

    Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Dizocilpine Maleate; Drug Interactions; Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Thiazoles; Thiazolidines

2005
Unchanged glutamine synthetase activity and increased NMDA receptor density in epileptic human neocortex: implications for the pathophysiology of epilepsy.
    Neurochemistry international, 2005, Volume: 47, Issue:6

    Topics: Adolescent; Adult; Aged; Amygdala; Binding, Competitive; Child; Child, Preschool; Epilepsy; Epilepsy, Temporal Lobe; Female; Glutamate-Ammonia Ligase; Glutamic Acid; Humans; Infant; Male; Middle Aged; Neocortex; Radioligand Assay; Receptor Aggregation; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes; Synaptic Transmission; Synaptosomes; Up-Regulation

2005
An astrocytic basis of epilepsy.
    Nature medicine, 2005, Volume: 11, Issue:9

    Topics: Action Potentials; Animals; Anticonvulsants; Astrocytes; Calcium Signaling; Epilepsy; Glutamic Acid; Hippocampus; Photolysis; Rats; Rats, Sprague-Dawley

2005
Astrocytes get in the act in epilepsy.
    Nature medicine, 2005, Volume: 11, Issue:9

    Topics: Astrocytes; Epilepsy; Glutamic Acid; Humans; Neurons; Signal Transduction

2005
Astrocytic glutamate release-induced transient depolarization and epileptiform discharges in hippocampal CA1 pyramidal neurons.
    Journal of neurophysiology, 2005, Volume: 94, Issue:6

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Calcium; Diagnostic Imaging; Drug Interactions; Electric Stimulation; Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Membrane Potentials; Microscopy, Confocal; Neurons; Neurotoxins; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetanus Toxin; Tetrodotoxin; Time Factors

2005
Changes in behavior and amino acid neurotransmitters in the brain of rats with seizure induced by IL-1beta or IL-6.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2005, Volume: 25, Issue:3

    Topics: Animals; Behavior, Animal; Cerebral Cortex; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Immunohistochemistry; Interleukin-1; Interleukin-6; Male; Random Allocation; Rats; Rats, Sprague-Dawley

2005
Astrocytes have a key role in epilepsy.
    The Lancet. Neurology, 2005, Volume: 4, Issue:10

    Topics: Action Potentials; Animals; Astrocytes; Brain; Calcium Signaling; Cell Communication; Epilepsy; Glutamic Acid; Humans; Neurons; Synaptic Transmission

2005
Selective enhancement of tonic inhibition by increasing ambient GABA is insufficient to suppress excitotoxicity in hippocampal neurons.
    Biochemical and biophysical research communications, 2005, Dec-23, Volume: 338, Issue:3

    Topics: Animals; Cations, Divalent; Electrophysiology; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Magnesium; Neurons; Rats; Rats, Wistar; Receptors, GABA-A

2005
Glutamate metabolism in epilepsy: 13C-magnetic resonance spectroscopy observation in the human brain.
    Neuroreport, 2005, Dec-19, Volume: 16, Issue:18

    Topics: Adult; Brain; Carbon Isotopes; Epilepsy; Female; Glucose; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male

2005
Changes in extracellular neurotransmitters in the cerebrum of familial idiopathic epileptic shetland sheepdogs using an intracerebral microdialysis technique and immunohistochemical study for glutamate metabolism.
    The Journal of veterinary medical science, 2005, Volume: 67, Issue:11

    Topics: Amino Acid Transport System X-AG; Amino Acids; Animals; Dog Diseases; Dogs; Electroencephalography; Epilepsy; Glutamate-Ammonia Ligase; Glutamic Acid; Immunohistochemistry; Microdialysis; Neurotransmitter Agents; Telencephalon

2005
Late N-methyl-D-aspartate receptor blockade rescues hippocampal neurons from excitotoxic stress and death after 4-aminopyridine-induced epilepsy.
    The European journal of neuroscience, 2005, Volume: 22, Issue:12

    Topics: 4-Aminopyridine; Animals; Cell Count; Cell Death; Chelating Agents; Disease Models, Animal; Dizocilpine Maleate; Drug Interactions; Egtazic Acid; Electroencephalography; Epilepsy; Excitatory Amino Acid Antagonists; Functional Laterality; Glutamic Acid; Hippocampus; Male; Microdialysis; Nerve Degeneration; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Stress, Physiological; Time Factors

2005
Epileptogenesis and reduced inward rectifier potassium current in tuberous sclerosis complex-1-deficient astrocytes.
    Epilepsia, 2005, Volume: 46, Issue:12

    Topics: Animals; Astrocytes; Cells, Cultured; Cyclin-Dependent Kinase 2; Epilepsy; Extracellular Space; Genes, Tumor Suppressor; Glutamic Acid; Hippocampus; Mice; Mice, Knockout; Potassium; Potassium Channels, Inwardly Rectifying; Tuberous Sclerosis; Tuberous Sclerosis Complex 1 Protein; Tumor Suppressor Proteins

2005
Meditation potentially capable of increasing susceptibility to epilepsy - a follow-up hypothesis.
    Medical hypotheses, 2006, Volume: 66, Issue:5

    Topics: Brain; Clinical Trials as Topic; Disease Susceptibility; Electroencephalography; Epilepsy; Evidence-Based Medicine; Glutamic Acid; Humans; Meditation; Models, Neurological; Neurotransmitter Agents; Serotonin

2006
A brief study of a possible relation of epilepsy association with meditation.
    Medical hypotheses, 2006, Volume: 66, Issue:5

    Topics: Brain; Clinical Trials as Topic; Disease Susceptibility; Electroencephalography; Epilepsy; Evidence-Based Medicine; Glutamic Acid; Humans; Meditation; Models, Neurological; Neurotransmitter Agents; Serotonin

2006
Suppression of neuronal network excitability and seizure-like events by 2-methyl-4-oxo-3H-quinazoline-3-acetyl piperidine in juvenile rat hippocampus: involvement of a metabotropic glutamate receptor.
    Neurochemistry international, 2006, Volume: 49, Issue:1

    Topics: Age Factors; Animals; Anticonvulsants; Binding Sites; Calcium Channels; Cell Membrane; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Guanosine Triphosphate; Hippocampus; Male; Nerve Net; Neural Inhibition; Organ Culture Techniques; Patch-Clamp Techniques; Piperidines; Protein Subunits; Pyramidal Cells; Quinazolines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synaptic Transmission

2006
Facilitation of glutamatergic synaptic transmission in hippocampal CA1 area of rats with traumatic brain injury.
    Neuroscience letters, 2006, Jun-19, Volume: 401, Issue:1-2

    Topics: Action Potentials; Animals; Brain Injuries; Disease Models, Animal; Epilepsy; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Male; Neuronal Plasticity; Presynaptic Terminals; Pyramidal Cells; Rats; Rats, Wistar; Synaptic Transmission

2006
Enhanced cyclooxygenase-2 expression in olfactory-limbic forebrain following kainate-induced seizures.
    Neuroscience, 2006, Jul-07, Volume: 140, Issue:3

    Topics: Animals; Biomarkers; Convulsants; Cyclooxygenase 2; Disease Models, Animal; Encephalitis; Epilepsy; Gliosis; Glutamic Acid; Immunohistochemistry; Kainic Acid; Limbic System; Male; Microglia; Olfactory Pathways; Prosencephalon; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Up-Regulation

2006
Metabolic alteration transients during paroxysmal activity in an epileptic patient with fixation-off sensitivity: a case study.
    Magnetic resonance imaging, 2006, Volume: 24, Issue:4

    Topics: Adolescent; Epilepsy; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Narcolepsy; Sensitivity and Specificity

2006
Evidence that the Transcendental Meditation program prevents or decreases diseases of the nervous system and is specifically beneficial for epilepsy.
    Medical hypotheses, 2006, Volume: 67, Issue:2

    Topics: Electroencephalography; Epilepsy; Glutamic Acid; Humans; Meditation; Nervous System Diseases; Rest; Serotonin; Sleep

2006
Ongoing epileptiform activity in the post-ischemic hippocampus is associated with a permanent shift of the excitatory-inhibitory synaptic balance in CA3 pyramidal neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Jun-28, Volume: 26, Issue:26

    Topics: Animals; Electroencephalography; Electrophysiology; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Interneurons; Male; Nerve Endings; Neural Inhibition; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Reperfusion Injury; Synapses; Synaptic Transmission

2006
The endocannabinoid system controls key epileptogenic circuits in the hippocampus.
    Neuron, 2006, Aug-17, Volume: 51, Issue:4

    Topics: Analysis of Variance; Animals; Behavior, Animal; Benzoxazines; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cannabinoid Receptor Modulators; Endocannabinoids; Epilepsy; gamma-Aminobutyric Acid; Gene Expression; Glutamic Acid; Hippocampus; Kainic Acid; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morpholines; Naphthalenes; Nerve Net; Pyramidal Cells; Receptor, Cannabinoid, CB1; Reverse Transcriptase Polymerase Chain Reaction; Vesicular Glutamate Transport Protein 1

2006
Astrocytic glutamate is not necessary for the generation of epileptiform neuronal activity in hippocampal slices.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Sep-06, Volume: 26, Issue:36

    Topics: Action Potentials; Animals; Astrocytes; Biological Clocks; Cell Communication; Cells, Cultured; Epilepsy; Glutamic Acid; Hippocampus; Mice; Mice, Inbred C57BL; Pyramidal Cells

2006
Altered calcium/calmodulin kinase II activity changes calcium homeostasis that underlies epileptiform activity in hippocampal neurons in culture.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 319, Issue:3

    Topics: Algorithms; Animals; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Data Interpretation, Statistical; Enzyme Inhibitors; Epilepsy; Fluorescent Dyes; Glutamic Acid; Hippocampus; Homeostasis; Immunohistochemistry; Magnesium; Mutation, Missense; Neurons; Oligonucleotides, Antisense; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley

2006
Changes in glial glutamate transporters in human epileptogenic hippocampus: inadequate explanation for high extracellular glutamate during seizures.
    Neurobiology of disease, 2007, Volume: 25, Issue:2

    Topics: Adolescent; Adult; Amino Acid Transport System X-AG; Astrocytes; Child; Child, Preschool; Down-Regulation; Epilepsy; Epilepsy, Temporal Lobe; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Extracellular Fluid; Female; Glutamic Acid; Hippocampus; Humans; Immunohistochemistry; Male; Microscopy, Electron, Transmission; Middle Aged; Up-Regulation

2007
Anatomic and electrophysiologic evidence for a proconvulsive circuit in the dentate gyrus of reeler mutant mice, an animal model of diffuse cortical malformation.
    Developmental neuroscience, 2007, Volume: 29, Issue:1-2

    Topics: Action Potentials; Animals; Coloring Agents; Dentate Gyrus; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Mice; Mice, Neurologic Mutants; Mossy Fibers, Hippocampal; Nervous System Malformations; Neural Pathways; Organ Culture Techniques; Receptors, Glutamate; Synaptic Transmission

2007
Recurrent seizures and the molecular maturation of hippocampal and neocortical glutamatergic synapses.
    Developmental neuroscience, 2007, Volume: 29, Issue:1-2

    Topics: Aging; Animals; Cell Differentiation; Convulsants; Dendritic Spines; Disks Large Homolog 4 Protein; Down-Regulation; Epilepsy; Glutamic Acid; Guanylate Kinases; Hippocampus; Intracellular Signaling Peptides and Proteins; Learning Disabilities; Membrane Proteins; Mice; Mice, Inbred C57BL; Neocortex; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Recurrence; Synapses; Synaptic Transmission

2007
The tripartite synapse: roles for gliotransmission in health and disease.
    Trends in molecular medicine, 2007, Volume: 13, Issue:2

    Topics: Adenosine Triphosphate; Animals; Astrocytes; Calcium Signaling; Epilepsy; Glutamic Acid; Humans; Models, Neurological; Neuronal Plasticity; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Spinal Cord Injuries; Synapses; Synaptic Transmission

2007
Altered excitability and distribution of NMDA receptor subunit proteins in cortical layers of rat pups following multiple perinatal seizures.
    Brain research, 2007, May-11, Volume: 1145

    Topics: Action Potentials; Aging; Animals; Animals, Newborn; Cerebral Cortex; Electroencephalography; Epilepsy; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Immunohistochemistry; Kainic Acid; Male; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Up-Regulation

2007
Rat epileptic seizures evoked by BmK alphaIV and its possible mechanisms involved in sodium channels.
    Toxicology and applied pharmacology, 2007, May-01, Volume: 220, Issue:3

    Topics: Animals; Calcium; Cerebral Cortex; Dose-Response Relationship, Drug; Electroencephalography; Electrophysiology; Epilepsy; Fluorometry; Glutamic Acid; Injections, Intraventricular; Male; Potassium Chloride; Rats; Rats, Sprague-Dawley; Scorpion Venoms; Sodium; Sodium Channel Blockers; Sodium Channels; Synaptosomes; Tetrodotoxin; Time Factors

2007
Synaptic responses in superficial layers of medial entorhinal cortex from rats with kainate-induced epilepsy.
    Neurobiology of disease, 2007, Volume: 26, Issue:2

    Topics: Animals; Convulsants; Disease Models, Animal; Electric Stimulation; Entorhinal Cortex; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Interneurons; Isoenzymes; Kainic Acid; Male; Neural Inhibition; Neural Pathways; Organ Culture Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Synaptic Transmission

2007
Apoptosis signalling pathways in seizure-induced neuronal death and epilepsy.
    Biochemical Society transactions, 2007, Volume: 35, Issue:Pt 2

    Topics: Apoptosis; Brain; Caspases; Cell Death; Endoplasmic Reticulum; Epilepsy; Glutamic Acid; Humans; Necrosis; Neurons; Proto-Oncogene Proteins c-bcl-2; Seizures; Signal Transduction

2007
Group I metabotropic glutamate receptor-dependent TRPC channel trafficking in hippocampal neurons.
    Journal of neurochemistry, 2007, Volume: 101, Issue:2

    Topics: Action Potentials; Animals; Calcium Channel Blockers; Cell Membrane; Convulsants; Cytoplasm; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Isoenzymes; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Organ Culture Techniques; Phospholipase C beta; Protein Transport; Receptors, Metabotropic Glutamate; TRPC Cation Channels; Type C Phospholipases

2007
Evidence against enhanced glutamate transport in the anticonvulsant mechanism of the ketogenic diet.
    Epilepsy research, 2007, Volume: 74, Issue:2-3

    Topics: Amino Acid Transport System X-AG; Animals; Astrocytes; Blotting, Western; Epilepsy; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glutamic Acid; Hippocampus; Ketones; Male; Microscopy, Electron; Nerve Tissue Proteins; Neurons; Rats; Rats, Sprague-Dawley; Subcellular Fractions

2007
Functional role of mGluR1 and mGluR4 in pilocarpine-induced temporal lobe epilepsy.
    Neurobiology of disease, 2007, Volume: 26, Issue:3

    Topics: Animals; Convulsants; Disease Models, Animal; Down-Regulation; Epilepsy; Epilepsy, Temporal Lobe; Gene Expression Regulation; Genetic Predisposition to Disease; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Mice; Mice, Knockout; Mice, Transgenic; Nerve Degeneration; Neurons; Pilocarpine; Receptors, Metabotropic Glutamate; Recombinant Fusion Proteins; Up-Regulation

2007
The effect of sodium valproate on proton MRS visible neurochemical concentrations.
    Epilepsy research, 2007, Volume: 74, Issue:2-3

    Topics: Adolescent; Adult; Algorithms; Anticonvulsants; Brain Chemistry; Dipeptides; Epilepsy; Female; Glutamic Acid; Glutamine; Humans; Inositol; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Valproic Acid

2007
Functional role for redox in the epileptogenesis: molecular regulation of glutamate in the hippocampus of FeCl3-induced limbic epilepsy model.
    Experimental brain research, 2007, Volume: 181, Issue:4

    Topics: Animals; Behavior, Animal; Chlorides; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Ferric Compounds; Gene Expression Regulation; Glutamic Acid; Hippocampus; Male; Microdialysis; Oxidation-Reduction; Rats; Rats, Wistar; Statistics, Nonparametric

2007
Small-world network topology of hippocampal neuronal network is lost, in an in vitro glutamate injury model of epilepsy.
    The European journal of neuroscience, 2007, Volume: 25, Issue:11

    Topics: Action Potentials; Animals; Cells, Cultured; Disease Models, Animal; Epilepsy; Glutamic Acid; Hippocampus; In Vitro Techniques; Nerve Net; Nonlinear Dynamics; Normal Distribution; Patch-Clamp Techniques; Rats; Rats, Wistar; Time Factors

2007
Leukoencephalopathy upon disruption of the chloride channel ClC-2.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Jun-13, Volume: 27, Issue:24

    Topics: Age Factors; Animals; Axons; Blood-Brain Barrier; Brain; Brain Diseases; Canavan Disease; Chloride Channels; CLC-2 Chloride Channels; Demyelinating Diseases; Epilepsy; Glutamic Acid; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Mutation; Myelin Sheath; RNA, Complementary; Subcellular Fractions; Time Factors; Up-Regulation; Vacuoles

2007
Glutamate binding is altered in hippocampus and cortex of Wistar rats after pilocarpine-induced Status Epilepticus.
    Neuroscience letters, 2007, Aug-31, Volume: 424, Issue:1

    Topics: Animals; Binding Sites; Cerebral Cortex; Convulsants; Epilepsy; Glutamic Acid; Hippocampus; Ligands; Male; Neuronal Plasticity; Pilocarpine; Rats; Rats, Wistar; Receptors, Glutamate; Status Epilepticus; Synaptic Transmission

2007
Rhythmic spontaneous activity in the piriform cortex.
    Cerebral cortex (New York, N.Y. : 1991), 2008, Volume: 18, Issue:5

    Topics: Action Potentials; Animals; Electrophysiology; Epilepsy; Female; Ferrets; Glutamic Acid; Male; Neocortex; Olfactory Pathways; Organ Culture Techniques; Visual Cortex

2008
The opposite role of hippocampal mGluR1 in fear conditioning in kindled and non-kindled rats.
    Brain research, 2008, Jan-02, Volume: 1187

    Topics: Animals; Brain Chemistry; Conditioning, Psychological; Convulsants; Epilepsy; Excitatory Amino Acid Antagonists; Extracellular Fluid; Fear; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Kindling, Neurologic; Learning; Male; Microdialysis; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synaptic Transmission

2008
Characterization of alternatively spliced isoforms of AMPA receptor subunits encoding truncated receptors.
    Molecular and cellular neurosciences, 2008, Volume: 37, Issue:2

    Topics: Alternative Splicing; Animals; Cell Death; Cell Line; Cells, Cultured; Chick Embryo; Cytoprotection; Epilepsy; Glutamic Acid; Hippocampus; Humans; Mutation; Protein Isoforms; Protein Structure, Tertiary; Protein Subunits; Rats; Rats, Wistar; Receptors, AMPA; RNA, Messenger; Synaptic Transmission

2008
Decreased glutamate receptor binding and NMDA R1 gene expression in hippocampus of pilocarpine-induced epileptic rats: neuroprotective role of Bacopa monnieri extract.
    Epilepsy & behavior : E&B, 2008, Volume: 12, Issue:1

    Topics: Analysis of Variance; Animals; Bacopa; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Gene Expression Regulation; Glutamate Dehydrogenase; Glutamic Acid; Hippocampus; Male; Maze Learning; Phytotherapy; Pilocarpine; Plant Preparations; Protein Binding; Rats; Rats, Wistar; Reaction Time; Receptors, N-Methyl-D-Aspartate

2008
NMDA receptor-mediated excitotoxic neuronal apoptosis in vitro and in vivo occurs in an ER stress and PUMA independent manner.
    Journal of neurochemistry, 2008, Volume: 105, Issue:3

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Brain; Brain Ischemia; Calcium Signaling; Endoplasmic Reticulum; Epilepsy; Female; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Neurons; Neurotoxins; Organ Culture Techniques; Oxidative Stress; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tumor Suppressor Proteins; Tunicamycin

2008
Thrombin induces long-term potentiation of reactivity to afferent stimulation and facilitates epileptic seizures in rat hippocampal slices: toward understanding the functional consequences of cerebrovascular insults.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Jan-16, Volume: 28, Issue:3

    Topics: Afferent Pathways; Animals; Animals, Newborn; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Epilepsy; Glutamic Acid; Hemostatics; Hippocampus; Long-Term Potentiation; Male; Peptide Fragments; Potassium; Pyrroles; Quinazolines; Rats; Rats, Wistar; Receptor, PAR-1; Thrombin

2008
Neuroprotective effect caused by MPEP, an antagonist of metabotropic glutamate receptor mGluR5, on seizures induced by pilocarpine in 21-day-old rats.
    Brain research, 2008, Mar-10, Volume: 1198

    Topics: Acetylcholinesterase; Animals; Brain; Convulsants; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Muscarinic Agonists; Nerve Degeneration; Neuroprotective Agents; Oxidative Stress; Pilocarpine; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Synaptic Transmission; Treatment Outcome

2008
Change of extracellular glutamate and gamma-aminobutyric acid in substantia nigra and globus pallidus during electrical stimulation of subthalamic nucleus in epileptic rats.
    Stereotactic and functional neurosurgery, 2008, Volume: 86, Issue:4

    Topics: Animals; Deep Brain Stimulation; Epilepsy; Extracellular Fluid; gamma-Aminobutyric Acid; Globus Pallidus; Glutamic Acid; Male; Rats; Rats, Wistar; Substantia Nigra; Subthalamic Nucleus

2008
[Glutamate as a transmitter in the CNS and its presumed significance in the pathogenesis of cerebral seizure forms--recent aspects].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1983, Volume: 35, Issue:2

    Topics: Brain; Epilepsy; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Neural Pathways; Neurons; Synaptic Transmission

1983
Evidence for a role of neurotransmitters in the mechanism of topical convulsant models.
    Federation proceedings, 1984, Volume: 43, Issue:10

    Topics: Acetylcholine; Acetylcholinesterase; Animals; Aspartic Acid; Brain; Choline O-Acetyltransferase; Disease Models, Animal; Dopamine; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Neurotransmitter Agents; Norepinephrine; Rats; Seizures; Taurine

1984
Role of metabotropic glutamate receptor subtypes in the patterning of epileptiform activities in vitro.
    Journal of neurophysiology, 1995, Volume: 74, Issue:2

    Topics: Animals; Epilepsy; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Picrotoxin; Receptors, Metabotropic Glutamate; Time Factors

1995
Early-onset epilepsy and postnatal lethality associated with an editing-deficient GluR-B allele in mice.
    Science (New York, N.Y.), 1995, Dec-08, Volume: 270, Issue:5242

    Topics: Alleles; Animals; Base Sequence; Calcium; Epilepsy; Gene Targeting; Glutamic Acid; Heterozygote; Hippocampus; In Situ Hybridization; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Nerve Degeneration; Neurons; Polymerase Chain Reaction; Purkinje Cells; Pyramidal Cells; Receptors, AMPA; RNA Editing; RNA Precursors

1995
The role of free radicals in NMDA-dependent neurotoxicity.
    Progress in brain research, 1994, Volume: 103

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Cells, Cultured; Cerebellar Cortex; Cyclic GMP; Electron Spin Resonance Spectroscopy; Enzyme Activation; Epilepsy; Feedback; Free Radicals; Glutamic Acid; Guanylate Cyclase; Kindling, Neurologic; Mice; Molsidomine; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Receptors, N-Methyl-D-Aspartate

1994
Initial observations on effect of vigabatrin on in vivo 1H spectroscopic measurements of gamma-aminobutyric acid, glutamate, and glutamine in human brain.
    Epilepsia, 1995, Volume: 36, Issue:5

    Topics: Adult; Anticonvulsants; Brain; Brain Chemistry; Epilepsy; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Occipital Lobe; Vigabatrin

1995
Alterations in glutamate but not GABAA receptor subunit expression as a consequence of epileptiform activity in vitro.
    Neuroscience, 1995, Volume: 67, Issue:4

    Topics: Animals; Autoradiography; Cells, Cultured; Epilepsy; Gene Expression; Glutamic Acid; Hippocampus; In Situ Hybridization; In Vitro Techniques; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; RNA, Messenger

1995
Preservation of hippocampal NMDA receptors may be crucial for spatial learning after epileptic seizures in rats.
    Brain research, 1993, Oct-15, Volume: 625, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Animals; Cognition Disorders; Electric Stimulation; Epilepsy; Glutamates; Glutamic Acid; Hippocampus; Learning; Male; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Somatostatin; Space Perception

1993
Enhanced aspartate release related to epilepsy in (EL) mice.
    Journal of neurochemistry, 1994, Volume: 63, Issue:2

    Topics: Aging; Animals; Aspartic Acid; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Potassium; Seizures; Species Specificity

1994
Glutamate in pyridoxine-dependent epilepsy: neurotoxic glutamate concentration in the cerebrospinal fluid and its normalization by pyridoxine.
    Pediatrics, 1994, Volume: 94, Issue:3

    Topics: Adrenocorticotropic Hormone; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; Genes, Recessive; Glutamates; Glutamic Acid; Head; Humans; Infant; Intellectual Disability; Male; Neurotransmitter Agents; Pyridoxal Phosphate; Pyridoxine

1994
Changes in oxygenation states of rat brain tissues during glutamate-related epileptic seizures--near-infrared study.
    Advances in experimental medicine and biology, 1994, Volume: 345

    Topics: Animals; Brain; Dizocilpine Maleate; Electroencephalography; Electron Transport Complex IV; Epilepsy; Glutamates; Glutamic Acid; Hemoglobins; Kainic Acid; Male; N-Methylaspartate; Oxidation-Reduction; Oxygen; Rats; Rats, Wistar; Spectrophotometry, Infrared

1994
Diminished potassium-stimulated GABA release in vivo in genetically epilepsy-prone rats.
    Neuroscience letters, 1994, Jul-04, Volume: 175, Issue:1-2

    Topics: Animals; Caudate Nucleus; Dose-Response Relationship, Drug; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Kinetics; Male; Microdialysis; Perfusion; Potassium; Rats; Rats, Sprague-Dawley; Reference Values; Time Factors

1994
NMDA-sensitive [3H]glutamate binding in the epileptic rat hippocampus: an autoradiographic study.
    Neuroreport, 1993, Volume: 4, Issue:1

    Topics: Animals; Autoradiography; Cell Death; Electroencephalography; Epilepsy; Glutamates; Glutamic Acid; Hippocampus; Histocytochemistry; Kinetics; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

1993
Extracellular amino acid levels in hippocampus during pilocarpine-induced seizures.
    Epilepsy research, 1993, Volume: 14, Issue:2

    Topics: Amino Acids; Animals; Behavior, Animal; Dialysis; Dicarboxylic Acids; Epilepsy; Glutamates; Glutamic Acid; Hippocampus; Male; Neurotransmitter Uptake Inhibitors; Pilocarpine; Proline; Pyrrolidines; Rats; Rats, Sprague-Dawley

1993
Amino acid levels in the cerebrospinal fluid of newly diagnosed epileptic patients: effect of vigabatrin and carbamazepine monotherapies.
    Journal of neurochemistry, 1993, Volume: 60, Issue:4

    Topics: Adolescent; Adult; Amino Acids; Aminocaproates; Carbamazepine; Carnosine; Epilepsy; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Humans; Male; Middle Aged; Vigabatrin

1993
Human epileptic astrocytes exhibit increased gap junction coupling.
    Glia, 1995, Volume: 15, Issue:2

    Topics: Astrocytes; Astrocytoma; Brain Neoplasms; Calcium; Cerebral Cortex; Culture Techniques; Electroencephalography; Epilepsy; Gap Junctions; Glutamic Acid; Humans; Magnetic Resonance Imaging; Microscopy, Fluorescence; Temporal Lobe

1995
Effect of alpha 2-adrenergic drugs dexmedetomidine and atipamezole on extracellular amino acid levels in vivo.
    European journal of pharmacology, 1995, Oct-24, Volume: 285, Issue:3

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amino Acids; Animals; Aspartic Acid; Calcium; Epilepsy; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Imidazoles; Male; Medetomidine; Microdialysis; Potassium; Rats; Rats, Wistar; Seizures; Spectrometry, Fluorescence

1995
Blockade of both epileptogenesis and glutamate release by (1S,3S)-ACPD, a presynaptic glutamate receptor agonist.
    Brain research, 1995, Nov-06, Volume: 698, Issue:1-2

    Topics: Animals; Cycloleucine; Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptosomes

1995
Evaluation of monoaminergic neurotransmitters in the acute focal ischemic human brain model by intracerebral in vivo microdialysis.
    Neurochemical research, 1996, Volume: 21, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Catecholamines; Chromatography, High Pressure Liquid; Epilepsy; Glutamic Acid; Humans; Hydroxyindoleacetic Acid; Ischemic Attack, Transient; Microdialysis; Norepinephrine; Serotonin; Temporal Lobe

1996
High-field MRS studies in brain slices.
    Magnetic resonance imaging, 1995, Volume: 13, Issue:8

    Topics: Animals; Cerebral Cortex; Culture Techniques; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Guinea Pigs; Ion Channels; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Membrane Potentials; N-Methylaspartate; Neurotransmitter Agents; Synaptic Transmission

1995
Localization of a gene for a glutamate binding subunit of a NMDA receptor (GRINA) to 8q24.
    Genomics, 1996, Feb-15, Volume: 32, Issue:1

    Topics: Animals; Base Sequence; Binding Sites; Chromosome Mapping; Chromosomes, Human, Pair 6; DNA Primers; DNA, Complementary; Epilepsy; Genetic Markers; Glutamic Acid; Humans; Hybrid Cells; In Situ Hybridization, Fluorescence; Infant, Newborn; Molecular Sequence Data; Protein Conformation; Rats; Receptors, N-Methyl-D-Aspartate

1996
Topiramate reduces abnormally high extracellular levels of glutamate and aspartate in the hippocampus of spontaneously epileptic rats (SER).
    Life sciences, 1996, Volume: 59, Issue:19

    Topics: Animals; Anticonvulsants; Aspartic Acid; Epilepsy; Excitatory Amino Acids; Female; Fructose; Glutamic Acid; Hippocampus; Male; Microdialysis; Rats; Rats, Mutant Strains; Rats, Wistar; Topiramate

1996
Effects of glutamate application on the rhythm of low magnesium-induced epileptiform activity in hippocampal slices of guinea-pigs.
    The European journal of neuroscience, 1996, Volume: 8, Issue:10

    Topics: Animals; Epilepsy; Evoked Potentials; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Magnesium; Periodicity

1996
Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1.
    Science (New York, N.Y.), 1997, Jun-13, Volume: 276, Issue:5319

    Topics: Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Biological Transport; Brain; Brain Injuries; Electroencephalography; Epilepsy; Gene Targeting; Glutamic Acid; Hippocampus; Mice; Mice, Inbred C57BL; Nerve Degeneration; Pyramidal Cells; Synapses; Synaptic Transmission

1997
Etiology of (CAG)n triplet repeat neurodegenerative diseases such as Huntington's disease is connected to stimulation of glutamate receptors.
    Medical hypotheses, 1997, Volume: 48, Issue:5

    Topics: Autoimmunity; Cerebrovascular Disorders; Epilepsy; Glutamic Acid; Humans; Huntington Disease; Minisatellite Repeats; Models, Biological; Nerve Degeneration; Receptors, Glutamate; Trinucleotide Repeats

1997
Glutamate transporter EAAC-1-deficient mice develop dicarboxylic aminoaciduria and behavioral abnormalities but no neurodegeneration.
    The EMBO journal, 1997, Jul-01, Volume: 16, Issue:13

    Topics: Amino Acid Sequence; Amino Acid Transport System X-AG; Amino Acids, Dicarboxylic; Animals; Brain; Carrier Proteins; Epilepsy; Excitatory Amino Acid Transporter 1; Female; Gene Targeting; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Motor Activity; Pentylenetetrazole; Phenotype; Rats; Symporters

1997
Muscarinic induction of synchronous population activity in the entorhinal cortex.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Sep-01, Volume: 17, Issue:17

    Topics: Animals; Carbachol; Electrophysiology; Entorhinal Cortex; Epilepsy; Glutamic Acid; Male; Muscarine; Muscarinic Agonists; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, GABA; Receptors, N-Methyl-D-Aspartate

1997
Strain differences in pentylenetetrazol-kindling development and subsequent potentiation effects.
    Brain research, 1997, Jul-18, Volume: 763, Issue:1

    Topics: Animals; Convulsants; Disease Models, Animal; Epilepsy; Glutamic Acid; Kindling, Neurologic; Male; Pentylenetetrazole; Rats; Rats, Wistar

1997
Development and pharmacology of glutamate uptake in audiogenic seizures.
    Epilepsy research. Supplement, 1996, Volume: 12

    Topics: Acoustic Stimulation; Age Factors; Animals; Brain; Brain Mapping; Culture Techniques; Electroencephalography; Epilepsy; Female; Genotype; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Seizures; Synaptic Transmission; Synaptosomes

1996
Short- and long-term alterations in glutamate transmission in the entorhinal cortex: relevance to epileptogenesis.
    Epilepsy research. Supplement, 1996, Volume: 12

    Topics: Animals; Brain Mapping; Culture Techniques; Entorhinal Cortex; Epilepsy; Evoked Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Long-Term Potentiation; Nerve Net; Neural Inhibition; Neuronal Plasticity; Neurons; Rats; Synaptic Transmission

1996
Role of glutamate and aspartate in epileptogenesis; contribution of microdialysis studies in animal and man.
    Epilepsy research. Supplement, 1996, Volume: 12

    Topics: Animals; Aspartic Acid; Brain; Brain Mapping; Electroencephalography; Epilepsies, Partial; Epilepsy; Evoked Potentials; Glutamic Acid; Humans; Microdialysis; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission

1996
Synaptic vesicle glutamate uptake in epileptic (EL) mice.
    Neurochemistry international, 1997, Volume: 31, Issue:4

    Topics: Adenosine Triphosphate; Aging; Animals; Brain; Epilepsy; Glutamic Acid; Handling, Psychological; Mice; Mice, Inbred Strains; Reference Values; Synaptic Vesicles

1997
Cerebrospinal fluid hypoxanthine, xanthine and uric acid levels may reflect glutamate-mediated excitotoxicity in different neurological diseases.
    Neuroscience letters, 1997, Nov-28, Volume: 238, Issue:1-2

    Topics: Adult; Albumins; Central Nervous System Diseases; Cerebrovascular Disorders; Chromatography, High Pressure Liquid; Epilepsy; Female; Glutamic Acid; Humans; Hypoxanthine; L-Lactate Dehydrogenase; Lactic Acid; Male; Meningitis, Viral; Middle Aged; Multiple Sclerosis; Serum Albumin; Spinal Cord Diseases; Uric Acid; Xanthine

1997
Specific group II metabotropic glutamate receptor activation inhibits the development of kindled epilepsy in rats.
    Brain research, 1998, Mar-23, Volume: 787, Issue:2

    Topics: Animals; Anticonvulsants; Brain; Dose-Response Relationship, Drug; Epilepsy; Excitatory Amino Acid Agonists; Glutamic Acid; Kindling, Neurologic; Male; Monosaccharide Transport Proteins; Proline; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptosomes

1998
Suppression by topiramate of epileptiform burst discharges in hippocampal CA3 neurons of spontaneously epileptic rat in vitro.
    Brain research, 1998, Apr-13, Volume: 789, Issue:2

    Topics: Action Potentials; Animals; Anticonvulsants; Calcium; Electrophysiology; Epilepsy; Female; Fructose; Glutamic Acid; Hippocampus; Male; Neurons; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Mutant Strains; Synaptic Transmission; Topiramate

1998
Nitric oxide in mechanisms of brain damage induced by neurotoxic effect of glutamate.
    Biochemistry. Biokhimiia, 1998, Volume: 63, Issue:7

    Topics: Animals; Brain; Brain Injuries; Brain Ischemia; Epilepsy; Glutamic Acid; Humans; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Signal Transduction

1998
Neuronal degeneration in rat forebrain resulting from D-amphetamine-induced convulsions is dependent on seizure severity and age.
    Brain research, 1998, Oct-26, Volume: 809, Issue:1

    Topics: Age Factors; Animals; Basal Ganglia; Behavior, Animal; Body Temperature; Catecholamines; Dextroamphetamine; Epilepsy; Glutamic Acid; Limbic System; Male; Nerve Degeneration; Prosencephalon; Rats; Rats, Sprague-Dawley; Sympathomimetics

1998
A gene expression approach to mapping the functional maturation of the hippocampus.
    Brain research. Molecular brain research, 1998, Dec-10, Volume: 63, Issue:1

    Topics: Animals; Brain Mapping; Denervation; Dentate Gyrus; Epilepsy; Excitatory Amino Acid Agonists; Gene Expression; Genes, Immediate-Early; Genes, Reporter; Glutamic Acid; Kainic Acid; Lac Operon; Mice; Mice, Transgenic; Proto-Oncogene Proteins c-fos; Pyramidal Cells; Signal Transduction

1998
Prolonged expression of zinc finger immediate-early gene mRNAs and decreased protein synthesis following kainic acid induced seizures.
    The European journal of neuroscience, 1999, Volume: 11, Issue:1

    Topics: Amygdala; Animals; Cerebral Cortex; Dentate Gyrus; DNA-Binding Proteins; Early Growth Response Protein 1; Early Growth Response Protein 2; Early Growth Response Protein 3; Epilepsy; Excitatory Amino Acid Agonists; Gene Expression Regulation; Genes, Immediate-Early; Glutamic Acid; Immediate-Early Proteins; In Situ Hybridization; Kainic Acid; Male; Nerve Tissue Proteins; Nuclear Receptor Subfamily 4, Group A, Member 1; Nuclear Receptor Subfamily 4, Group A, Member 2; Oligonucleotide Probes; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger; Transcription Factors; Zinc Fingers

1999
Q/R editing of the rat GluR5 and GluR6 kainate receptors in vivo and in vitro: evidence for independent developmental, pathological and cellular regulation.
    The European journal of neuroscience, 1999, Volume: 11, Issue:2

    Topics: Age Factors; Animals; Cells, Cultured; Cerebellum; Cerebral Cortex; DNA Primers; Epilepsy; Excitatory Amino Acid Agonists; Female; Gene Expression Regulation, Developmental; GluK2 Kainate Receptor; Glutamic Acid; Hippocampus; Kainic Acid; Male; Neuroglia; Neurons; Olfactory Bulb; Potassium; Pregnancy; Rats; Rats, Wistar; Receptors, Kainic Acid; RNA Editing; RNA, Messenger

1999
Modulation of the audiogenic seizure network by noradrenergic and glutamatergic receptors of the deep layers of superior colliculus.
    Brain research, 1999, Mar-13, Volume: 821, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Adrenergic alpha-Agonists; Animals; Epilepsy; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Inferior Colliculi; Male; Microinjections; Norepinephrine; Phenylephrine; Rats; Rats, Mutant Strains; Receptors, Adrenergic; Receptors, N-Methyl-D-Aspartate; Reticular Formation; Superior Colliculi

1999
Hippocampal neurotrophin and trk receptor mRNA levels are altered by local administration of nicotine, carbachol and pilocarpine.
    Brain research. Molecular brain research, 1999, Apr-06, Volume: 67, Issue:1

    Topics: Acetylcholine; Animals; Behavior, Animal; Brain Chemistry; Brain-Derived Neurotrophic Factor; Carbachol; Cell Death; Cholinergic Agonists; Cholinergic Fibers; Epilepsy; Gene Expression; Glutamic Acid; Hippocampus; In Situ Hybridization; Male; Muscarinic Agonists; Nerve Growth Factors; Neuroprotective Agents; Neurotrophin 3; Nicotine; Nicotinic Agonists; Pilocarpine; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptor, Ciliary Neurotrophic Factor; Receptor, Nerve Growth Factor; Receptor, trkA; Receptor, trkC; Receptors, Nerve Growth Factor; RNA, Messenger; Septal Nuclei; Synaptic Transmission

1999
Interleukin-1beta immunoreactivity and microglia are enhanced in the rat hippocampus by focal kainate application: functional evidence for enhancement of electrographic seizures.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Jun-15, Volume: 19, Issue:12

    Topics: Animals; Antibodies; Anticonvulsants; Antirheumatic Agents; Bicuculline; Cell Count; Electroencephalography; Enzyme-Linked Immunosorbent Assay; Epilepsy; Excitatory Amino Acid Agonists; GABA Antagonists; Glutamic Acid; Hippocampus; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Kainic Acid; Male; Microglia; Nerve Degeneration; Neurons; Piperazines; Rats; Rats, Sprague-Dawley; Sialoglycoproteins

1999
Nitric oxide and glutamate interaction in the control of cortical and hippocampal excitability.
    Epilepsia, 1999, Volume: 40, Issue:7

    Topics: Animals; Cerebral Cortex; Epilepsy; Glutamic Acid; Hippocampus; Male; Nitric Oxide; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex

1999
Changes in hippocampal and cortical B1 bradykinin receptor biological activity in two experimental models of epilepsy.
    Neuroscience, 1999, Volume: 92, Issue:3

    Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Cerebral Cortex; Electric Stimulation; Epilepsy; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Kallidin; Kindling, Neurologic; Male; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Receptors, Bradykinin

1999
Glycerol-induced seizure: involvement of IL-1beta and glutamate.
    Neuroreport, 1999, Jun-23, Volume: 10, Issue:9

    Topics: Animals; Behavior, Animal; Brain Chemistry; Dose-Response Relationship, Drug; Epilepsy; Female; Gene Expression; Glutamic Acid; Glycerol; Interleukin-1; Mice; Mice, Inbred BALB C; Neuroimmunomodulation; Oligonucleotide Probes; RNA, Messenger; Synaptosomes

1999
Polyunsaturated fatty acids modify mouse hippocampal neuronal excitability during excitotoxic or convulsant stimulation.
    Brain research, 1999, Oct-30, Volume: 846, Issue:1

    Topics: Action Potentials; Animals; Convulsants; Docosahexaenoic Acids; Eicosapentaenoic Acid; Epilepsy; Fatty Acids, Unsaturated; Glutamic Acid; Hippocampus; Male; Mice; Neurons; Neurotoxins; Oleic Acid; Patch-Clamp Techniques; Pentylenetetrazole; Platelet Aggregation Inhibitors; Stearic Acids

1999
N-methyl-D-aspartate receptor binding is altered and seizure potential reduced in pregnant rats.
    Brain research, 1999, Oct-09, Volume: 844, Issue:1-2

    Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Convulsants; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Hippocampus; Male; N-Methylaspartate; Pregnancy; Pregnancy, Animal; Radioligand Assay; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tritium

1999
Electrophysiological and morphological analyses of cortical neurons obtained from children with catastrophic epilepsy: dopamine receptor modulation of glutamatergic responses.
    Developmental neuroscience, 1999, Volume: 21, Issue:3-5

    Topics: Adolescent; Cerebral Cortex; Child; Child, Preschool; Dopamine; Dopamine Agonists; Electrophysiology; Epilepsy; Glutamic Acid; Humans; Immunohistochemistry; In Vitro Techniques; Infant; Infrared Rays; Iontophoresis; Neurons; Patch-Clamp Techniques; Receptors, Dopamine; Synapses

1999
Upregulation of NMDA receptors in hippocampus and cortex in the pentylenetetrazol-induced "kindling" model of epilepsy.
    Neurochemical research, 1999, Volume: 24, Issue:12

    Topics: Animals; Autoradiography; Dentate Gyrus; Dizocilpine Maleate; Epilepsy; Glutamic Acid; Hippocampus; Kindling, Neurologic; Male; Mice; Mice, Inbred BALB C; Pentylenetetrazole; Pyramidal Cells; Receptors, N-Methyl-D-Aspartate; Reference Values; Tritium; Up-Regulation

1999
Compensatory change in EAAC1 glutamate transporter in rat hippocampus CA1 region during kindling epileptogenesis.
    Neuroscience letters, 1999, Dec-10, Volume: 276, Issue:3

    Topics: Adaptation, Physiological; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Carrier Proteins; Dicarboxylic Acids; Epilepsy; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 3; Extracellular Space; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hippocampus; Immunoblotting; Kindling, Neurologic; Microdialysis; Pyrrolidines; Rats; Rats, Wistar; Symporters

1999
Ketone bodies do not directly alter excitatory or inhibitory hippocampal synaptic transmission.
    Neurology, 2000, Jan-25, Volume: 54, Issue:2

    Topics: 3-Hydroxybutyric Acid; 4-Aminopyridine; Acetoacetates; Animals; Cells, Cultured; Diet; Entorhinal Cortex; Epilepsy; Evoked Potentials; Excitatory Amino Acid Agonists; Fasting; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Kainic Acid; Ketosis; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Rats; Receptors, AMPA; Receptors, GABA-A; Receptors, Glycine; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical; Synaptic Membranes; Synaptic Transmission

2000
Epileptogenesis up-regulates metabotropic glutamate receptor activation of sodium-calcium exchange current in the amygdala.
    Journal of neurophysiology, 2000, Volume: 83, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Calcium; Dose-Response Relationship, Drug; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Kindling, Neurologic; Male; Membrane Potentials; Methoxyhydroxyphenylglycol; Phenylacetates; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Seizures; Sodium; Tetrodotoxin; Up-Regulation

2000
Localization of the A kinase anchoring protein AKAP79 in the human hippocampus.
    The European journal of neuroscience, 2000, Volume: 12, Issue:4

    Topics: A Kinase Anchor Proteins; Adaptor Proteins, Signal Transducing; Animals; Antibodies; Calcineurin; Carrier Proteins; Cyclic AMP-Dependent Protein Kinases; Dendrites; Epilepsy; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; Immunoenzyme Techniques; Immunohistochemistry; Interneurons; Male; Microscopy, Electron; Pyramidal Cells; Rabbits; Synapses; Tissue Embedding

2000
Guanosine and GMP prevent seizures induced by quinolinic acid in mice.
    Brain research, 2000, May-02, Volume: 864, Issue:1

    Topics: Animals; Anticonvulsants; Central Nervous System; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Guanosine; Guanosine Monophosphate; Male; Mice; Neurons; Picrotoxin; Quinolinic Acid; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Seizures; Time Factors

2000
Temporal progression of kainic acid induced neuronal and myelin degeneration in the rat forebrain.
    Brain research, 2000, May-02, Volume: 864, Issue:1

    Topics: Amygdala; Animals; Basal Ganglia; Coloring Agents; Denervation; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Agonists; Female; Fluorescent Dyes; Glutamic Acid; Hippocampus; Hypothalamus; Kainic Acid; Myelin Sheath; Nerve Degeneration; Neurons; Neurotoxins; Olfactory Pathways; Parietal Lobe; Phosphates; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Status Epilepticus; Thalamus; Time Factors

2000
GABA(A)-mediated toxicity of hippocampal neurons in vitro.
    Journal of neurochemistry, 2000, Volume: 74, Issue:6

    Topics: Animals; Anticonvulsants; Bicuculline; Cell Survival; Cells, Cultured; Epilepsy; Female; Fetus; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Potassium Chloride; Pregnancy; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Vigabatrin

2000
Evidence for coupling between glucose metabolism and glutamate cycling using FDG PET and 1H magnetic resonance spectroscopy in patients with epilepsy.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2000, Volume: 20, Issue:5

    Topics: Adolescent; Adult; Child; Child, Preschool; Epilepsy; Female; Fluorodeoxyglucose F18; Glucose; Glutamic Acid; Humans; Infant; Magnetic Resonance Spectroscopy; Male; Protons; Radiopharmaceuticals; Tomography, Emission-Computed

2000
Intrastriatal administration of 5-aminolevulinic acid induces convulsions and body asymmetry through glutamatergic mechanisms.
    Brain research, 2000, Jun-16, Volume: 868, Issue:1

    Topics: Aminolevulinic Acid; Animals; Convulsants; Corpus Striatum; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Antagonists; Female; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Microinjections; Muscimol; Quinoxalines; Rats; Rats, Wistar

2000
Excitatory amino acids modulate epileptogenesis in the brain stem.
    Neuroreport, 2000, Jun-05, Volume: 11, Issue:8

    Topics: Animals; Brain Stem; Carbachol; Cholinergic Agonists; Dizocilpine Maleate; Drug Synergism; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Male; Microinjections; Pons; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Time Factors

2000
Zinc-rich synaptic boutons in human temporal cortex biopsies.
    Neuroscience, 2000, Volume: 98, Issue:3

    Topics: Biopsy; Epilepsy; Female; Glutamic Acid; Humans; Male; Presynaptic Terminals; Receptors, AMPA; Temporal Lobe; Zinc

2000
Plasticity of excitatory amino acid transporters in experimental epilepsy.
    Epilepsia, 2000, Volume: 41 Suppl 6

    Topics: Animals; Dicarboxylic Acids; Epilepsy; Female; Glutamic Acid; Hippocampus; Kainic Acid; Magnesium; Neuronal Plasticity; Neurotransmitter Uptake Inhibitors; Pilocarpine; Propionates; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Up-Regulation; Veratridine

2000
Induction of spontaneous recurrent epileptiform discharges causes long-term changes in intracellular calcium homeostatic mechanisms.
    Cell calcium, 2000, Volume: 28, Issue:3

    Topics: Animals; Animals, Newborn; Calcium; Cell Nucleus; Cells, Cultured; Cytosol; Epilepsy; Glutamic Acid; Hippocampus; Homeostasis; Image Enhancement; Microscopy, Fluorescence; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley

2000
Kindled seizure-evoked somatostatin release in the hippocampus: inhibition by MK-801.
    Neuroreport, 2000, Sep-28, Volume: 11, Issue:14

    Topics: Amygdala; Animals; Disease Models, Animal; Dizocilpine Maleate; Electric Stimulation; Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kindling, Neurologic; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Seizures; Somatostatin

2000
Seizures induce simultaneous GABAergic and glutamatergic transmission in the dentate gyrus-CA3 system.
    Journal of neurophysiology, 2000, Volume: 84, Issue:6

    Topics: Amygdala; Animals; Dentate Gyrus; Electric Stimulation; Electrodes, Implanted; Epilepsy; Evoked Potentials; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Kindling, Neurologic; Neural Inhibition; Pentylenetetrazole; Pyramidal Cells; Rats; Rats, Wistar; Reaction Time; Seizures; Synapses; Synaptic Transmission

2000
Seizures and neurodegeneration induced by 4-aminopyridine in rat hippocampus in vivo: role of glutamate- and GABA-mediated neurotransmission and of ion channels.
    Neuroscience, 2000, Volume: 101, Issue:3

    Topics: 4-Aminopyridine; Animals; Epilepsy; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Ion Channels; Male; Nerve Degeneration; Neurons; Neurotoxins; omega-Conotoxin GVIA; Potassium Channels; Rats; Rats, Wistar; Receptors, Glutamate; Riluzole; Seizures; Sodium Channel Blockers; Sodium Channels; Synaptic Transmission

2000
Kindling phenomena induced by the repeated short-term high potassium stimuli in the ventral hippocampus of rats: on-line monitoring of extracellular glutamate overflow.
    Experimental brain research, 2000, Volume: 135, Issue:2

    Topics: Action Potentials; Animals; Computers; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Extracellular Space; Glutamic Acid; Hippocampus; Kindling, Neurologic; Male; Microdialysis; Monitoring, Physiologic; Potassium; Rats; Rats, Wistar; Time Factors

2000
Effect of extracellular long-time microperfusion of high concentrations of glutamate and glycine on picrotoxin seizure thresholds in the hippocampus of freely moving rats.
    Brain research, 2001, Jan-05, Volume: 888, Issue:1

    Topics: Animals; Epilepsy; Excitatory Amino Acid Antagonists; Extracellular Space; GABA Antagonists; Glutamic Acid; Glycine; Hippocampus; Kynurenic Acid; Male; Microdialysis; Motor Activity; Neural Inhibition; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures

2001
Collapse of extracellular glutamate regulation during epileptogenesis: down-regulation and functional failure of glutamate transporter function in rats with chronic seizures induced by kainic acid.
    Journal of neurochemistry, 2001, Volume: 76, Issue:3

    Topics: Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Carrier Proteins; Chronic Disease; Dose-Response Relationship, Drug; Down-Regulation; Epilepsy; Extracellular Space; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Kainic Acid; Male; Membrane Proteins; Membrane Transport Proteins; Organic Anion Transporters; Potassium; Rats; Rats, Wistar; RNA, Messenger; Seizures

2001
Electrophysiological and morphological characterization of neurons within neocortical ectopias.
    Journal of neurophysiology, 2001, Volume: 85, Issue:2

    Topics: Afferent Pathways; Animals; Brain Diseases; Choristoma; Electrophysiology; Epilepsy; Female; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice; Mice, Inbred NZB; Mice, Inbred Strains; Neocortex; Neural Inhibition; Neurons; Synapses

2001
Extracellular amino acid levels measured with intracerebral microdialysis in the model of posttraumatic epilepsy induced by intracortical iron injection.
    Epilepsy research, 2001, Volume: 43, Issue:2

    Topics: Amino Acids; Animals; Aspartic Acid; Brain; Cerebral Cortex; Craniocerebral Trauma; Electroencephalography; Epilepsy; Extracellular Space; Ferrous Compounds; Glutamic Acid; Injections; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Serine

2001
Hippocampal neurons of mice deficient in DNA-dependent protein kinase exhibit increased vulnerability to DNA damage, oxidative stress and excitotoxicity.
    Brain research. Molecular brain research, 2001, Mar-05, Volume: 87, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Camptothecin; DNA Damage; DNA-Activated Protein Kinase; DNA-Binding Proteins; Enzyme Inhibitors; Epilepsy; Etoposide; Glutamic Acid; Hippocampus; Mice; Mice, SCID; Neurons; Neurotoxins; Nucleic Acid Synthesis Inhibitors; Oxidative Stress; Protein Serine-Threonine Kinases; Topoisomerase I Inhibitors

2001
Dietary restriction stimulates BDNF production in the brain and thereby protects neurons against excitotoxic injury.
    Journal of molecular neuroscience : MN, 2001, Volume: 16, Issue:1

    Topics: Actins; Animals; Antibodies; Brain; Brain-Derived Neurotrophic Factor; Cell Survival; Cerebral Cortex; Epilepsy; Food Deprivation; Glutamic Acid; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Neostriatum; Nerve Growth Factor; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Rats, Sprague-Dawley; RNA, Messenger

2001
Spreading depression in human neocortical slices.
    Brain research, 2001, Jul-06, Volume: 906, Issue:1-2

    Topics: Adolescent; Adult; Amiloride; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Child; Cortical Spreading Depression; Diuretics; Epilepsy; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Male; Membrane Potentials; Middle Aged; Neocortex; Neurons; Nickel; Potassium; Potassium Chloride; Receptors, N-Methyl-D-Aspartate

2001
Changes in the colocalization of glutamate ionotropic receptor subunits in the human epileptic temporal lobe cortex.
    Experimental brain research, 2001, Volume: 138, Issue:3

    Topics: Adult; Down-Regulation; Epilepsy; Glutamic Acid; Humans; Immunohistochemistry; Male; Pyramidal Cells; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Temporal Lobe; Up-Regulation

2001
Sequential changes in AMPA and NMDA protein levels during Fe(3+)-induced epileptogenesis.
    Brain research. Molecular brain research, 2001, Aug-15, Volume: 92, Issue:1-2

    Topics: Amygdala; Animals; Calcium; Chlorides; Convulsants; Epilepsy; Ferric Compounds; Glutamic Acid; Hippocampus; Injections; Ion Transport; Male; Nerve Tissue Proteins; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures; Synaptic Membranes; Up-Regulation

2001
Post-insult activity is a major cause of delayed neuronal death in organotypic hippocampal slices exposed to glutamate.
    Neuroscience, 2001, Volume: 105, Issue:1

    Topics: Action Potentials; Animals; Brain Injuries; Brain Ischemia; Cell Death; Epilepsy; Glutamic Acid; Hippocampus; Nerve Degeneration; Nerve Net; Neurotoxins; Organ Culture Techniques; Pyramidal Cells; Rats; Tetrodotoxin; Time Factors

2001
Nociceptin reduces epileptiform events in CA3 hippocampus via presynaptic and postsynaptic mechanisms.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Sep-01, Volume: 21, Issue:17

    Topics: Animals; Epilepsy; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Indoles; Magnesium; Male; Mossy Fibers, Hippocampal; Nociceptin; Opioid Peptides; Patch-Clamp Techniques; Potassium; Pyramidal Cells; Pyridines; Rats; Rats, Sprague-Dawley; Synapses

2001
[Features of neurotransmitter pool in cerebrospinal fluid of patients with epilepsy].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2001, Volume: 101, Issue:6

    Topics: Adult; Aspartic Acid; Brain; Epilepsy; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Humans; Male; Middle Aged; Neurotransmitter Agents; Severity of Illness Index; Taurine

2001
Effect of orally administered guanosine on seizures and death induced by glutamatergic agents.
    Brain research, 2001, Sep-07, Volume: 912, Issue:2

    Topics: Animals; Brain; Caffeine; Death; Dizocilpine Maleate; Dose-Response Relationship, Drug; Elapid Venoms; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Guanosine; Kainic Acid; Male; Mice; Neuroprotective Agents; Phenobarbital; Phosphodiesterase Inhibitors; Quinolinic Acid; Receptors, Purinergic P1

2001
Glutamate transport in rat cerebellar granule cells is impaired by inorganic epileptogenic agents.
    Neuroscience letters, 2001, Sep-14, Volume: 310, Issue:2-3

    Topics: Amino Acid Transport System X-AG; Animals; Biological Transport; Cells, Cultured; Cerebellum; Cobalt; Convulsants; Epilepsy; Glutamic Acid; Neurons; Nickel; Patch-Clamp Techniques; Rats; Rats, Wistar

2001
Epileptogenesis induces long-term alterations in intracellular calcium release and sequestration mechanisms in the hippocampal neuronal culture model of epilepsy.
    Cell calcium, 2001, Volume: 30, Issue:4

    Topics: Animals; Boron Compounds; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Disease Models, Animal; Endoplasmic Reticulum; Epilepsy; Glutamic Acid; Hippocampus; Homeostasis; Microscopy, Fluorescence; Neuronal Plasticity; Neurons; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin

2001
Glutamate injury-induced epileptogenesis in hippocampal neurons: an in vitro model of stroke-induced "epilepsy".
    Stroke, 2001, Volume: 32, Issue:10

    Topics: Action Potentials; Animals; Anticonvulsants; Cell Size; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Models, Biological; Nerve Net; Neurons; Patch-Clamp Techniques; Phenobarbital; Rats; Rats, Sprague-Dawley; Stroke

2001
NR2B-containing NMDA autoreceptors at synapses on entorhinal cortical neurons.
    Journal of neurophysiology, 2001, Volume: 86, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; Animals; Autoreceptors; Calcium; Entorhinal Cortex; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; Neurons; Piperidines; Presynaptic Terminals; Quinolinic Acids; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin

2001
In vivo NO/cGMP signalling in the hippocampus.
    Neurochemical research, 2001, Volume: 26, Issue:8-9

    Topics: Aging; Animals; Cyclic GMP; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Nitric Oxide; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Signal Transduction

2001
Epileptiform activity in the nucleus accumbens induced by GABA(A) receptor antagonists in rat forebrain slices is of cortical origin.
    Experimental brain research, 2001, Volume: 141, Issue:2

    Topics: Animals; Cerebral Cortex; Cerebral Decortication; Electric Stimulation; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-A Receptor Antagonists; Glutamic Acid; Male; Neural Inhibition; Neural Pathways; Neurons; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, AMPA; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission

2001
Seizure susceptibility decreases with enhancement of rapid eye movement sleep.
    Brain research, 2001, Dec-20, Volume: 922, Issue:2

    Topics: Acetylcholine; Afferent Pathways; Amygdala; Animals; Carbachol; Causality; Cholinergic Agonists; Electroencephalography; Epilepsy; Glutamic Acid; Kindling, Neurologic; Male; Pons; Rats; Rats, Wistar; Reticular Formation; Seizures; Sleep Deprivation; Sleep, REM; Synaptic Transmission; Vagus Nerve

2001
Polyamine metabolism and glutamate receptor agonists-mediated excitotoxicity in the rat brain.
    Journal of neuroscience research, 2001, Dec-15, Volume: 66, Issue:6

    Topics: Animals; Biogenic Polyamines; Biomarkers; Body Weight; Brain; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Agonists; Frontal Lobe; Functional Laterality; Glutamic Acid; Hippocampus; Injections, Intraventricular; Male; Nerve Degeneration; Neurons; Neurotoxins; Putrescine; Rats; Rats, Wistar; Receptors, Glutamate; Spermidine; Spermine

2001
Glutamate transporters alterations in the reorganizing dentate gyrus are associated with progressive seizure activity in chronic epileptic rats.
    The Journal of comparative neurology, 2002, Jan-21, Volume: 442, Issue:4

    Topics: Amino Acid Transport System X-AG; Animals; Carrier Proteins; Dentate Gyrus; Down-Regulation; Electric Stimulation; Epilepsy; Epilepsy, Temporal Lobe; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Immunohistochemistry; Male; Mossy Fibers, Hippocampal; Neuroglia; Neuronal Plasticity; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Status Epilepticus; Symporters; Up-Regulation

2002
Agrin regulates neuronal responses to excitatory neurotransmitters in vitro and in vivo.
    Molecular and cellular neurosciences, 2002, Volume: 19, Issue:1

    Topics: Agrin; Animals; Calcium Channels; Calcium Signaling; Cell Communication; Cells, Cultured; Cerebral Cortex; Electrophysiology; Epilepsy; Excitatory Amino Acid Agonists; Genotype; Glutamic Acid; Heterozygote; Homozygote; In Vitro Techniques; Kainic Acid; Mice; Neurons; Neurotoxins; Nicotine; Nicotinic Agonists; Phenotype; Proto-Oncogene Proteins c-fos; Receptors, Glutamate

2002
Tricarboxylic acid cycle of glia in the in vivo human brain.
    NMR in biomedicine, 2002, Volume: 15, Issue:1

    Topics: Acetates; Adult; Bicarbonates; Brain; Carbon Isotopes; Citric Acid Cycle; Epilepsy; Female; Glutamic Acid; Glutamine; Humans; Kinetics; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuroglia; Oxidation-Reduction; Valproic Acid

2002
Dopamine D2 receptor signaling controls neuronal cell death induced by muscarinic and glutamatergic drugs.
    Molecular and cellular neurosciences, 2002, Volume: 19, Issue:2

    Topics: Acetylcholine; Animals; Behavior, Animal; Cell Death; Dose-Response Relationship, Drug; Epilepsy; Excitatory Amino Acid Agonists; Female; Genotype; Glutamic Acid; Kainic Acid; Limbic System; Male; Mice; Mice, Knockout; Molecular Sequence Data; Muscarinic Agonists; Nerve Degeneration; Pilocarpine; Receptors, Dopamine D2; Receptors, Muscarinic; RNA, Messenger; Signal Transduction; Synaptic Transmission

2002
Network interactions mediated by new excitatory connections between CA1 pyramidal cells in rats with kainate-induced epilepsy.
    Journal of neurophysiology, 2002, Volume: 87, Issue:3

    Topics: Action Potentials; Animals; Bicuculline; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; Hippocampus; Kainic Acid; Male; Neural Pathways; Patch-Clamp Techniques; Periodicity; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Stimulation, Chemical

2002
[Adenosine inhibits spontaneous and glutamate induced discharges of hippocampal CA1 neurons].
    Sheng li xue bao : [Acta physiologica Sinica], 2000, Volume: 52, Issue:4

    Topics: Adenosine; Animals; Electrophysiology; Epilepsy; Female; Glutamic Acid; Glyburide; Hippocampus; In Vitro Techniques; Male; Microelectrodes; Neurons; Rats; Rats, Sprague-Dawley

2000
NMDA receptor activation mediates hydrogen peroxide-induced pathophysiology in rat hippocampal slices.
    Journal of neurophysiology, 2002, Volume: 87, Issue:6

    Topics: 2-Amino-5-phosphonovalerate; Animals; Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Hydrogen Peroxide; Male; Organ Culture Techniques; Oxidants; Rats; Rats, Long-Evans; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate

2002
Downregulation of kainate receptors in the hippocampus following repeated seizures in immature rats.
    Brain research. Developmental brain research, 2002, Jun-30, Volume: 136, Issue:2

    Topics: Animals; Animals, Newborn; Binding Sites; Down-Regulation; Drug Administration Schedule; Epilepsy; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Hippocampus; Kainic Acid; Learning; Male; Memory; Nerve Degeneration; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Synaptic Transmission

2002
Glutamate-glutamine cycling in the epileptic human hippocampus.
    Epilepsia, 2002, Volume: 43, Issue:7

    Topics: Adolescent; Adult; Carbon Isotopes; Citric Acid Cycle; Energy Metabolism; Epilepsy; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons

2002
Apparent desensitization to glutamate: possible role in epilepsy.
    Epilepsy research. Supplement, 1992, Volume: 8

    Topics: Animals; Culture Techniques; Epilepsy; Glutamates; Glutamic Acid; Hippocampus; Membrane Potentials; Neural Inhibition; Neurons; Perfusion; Rats; Receptors, Glutamate; Synaptic Transmission

1992
Kindling seizure induction and excitatory amino acid.
    The Japanese journal of psychiatry and neurology, 1992, Volume: 46, Issue:2

    Topics: Animals; Aspartic Acid; Brain; Cats; Electric Stimulation; Epilepsy; Glutamates; Glutamic Acid; Kindling, Neurologic

1992
Genetically epilepsy-prone rats have increased brain regional activity of an enzyme which liberates glutamate from N-acetyl-aspartyl-glutamate.
    Brain research, 1992, Oct-09, Volume: 593, Issue:1

    Topics: Animals; Brain; Cell Membrane; Dipeptidases; Dipeptides; Epilepsy; Glutamate Carboxypeptidase II; Glutamates; Glutamic Acid; Male; Neuropeptides; Organ Specificity; Rats; Rats, Mutant Strains; Reference Values

1992
Enhanced aspartate release from hippocampal slices of epileptic (El) mice.
    Journal of neurochemistry, 1991, Volume: 56, Issue:3

    Topics: Animals; Aspartic Acid; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Potassium

1991
Physiology and pharmacology of epileptiform activity induced by 4-aminopyridine in rat hippocampal slices.
    Journal of neurophysiology, 1991, Volume: 65, Issue:4

    Topics: 4-Aminopyridine; Animals; Electrophysiology; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Synapses

1991
Synaptic responses of guinea pig cingulate cortical neurons in vitro.
    Journal of neurophysiology, 1991, Volume: 65, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Electrophysiology; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Guinea Pigs; Gyrus Cinguli; Magnesium; Neurons; Quinoxalines; Synapses

1991
Bursting-induced epileptiform EPSPs in slices of piriform cortex are generated by deep cells.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1991, Volume: 11, Issue:7

    Topics: Animals; Cerebral Cortex; Cobalt; Electric Stimulation; Electrophysiology; Epilepsy; Evoked Potentials; Glutamates; Glutamic Acid; Magnesium; Membrane Potentials; Potassium; Rats; Synapses

1991
NMDA receptor-mediated excitability in dendritically deformed dentate granule cells in pilocarpine-treated rats.
    Neuroscience letters, 1991, Aug-05, Volume: 129, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Animals; Dendrites; Epilepsy; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission

1991
Sensitivity of cerebellar Purkinje neurons to neurotransmitters in genetically epileptic rats.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:3

    Topics: Animals; Cerebellum; Electrophysiology; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Iontophoresis; Neurons; Neurotransmitter Agents; Purkinje Fibers; Rats; Rats, Inbred Strains

1991
Sequential changes in content of excitatory amino acids in the focus of epilepsy in seizure induction.
    The Japanese journal of psychiatry and neurology, 1991, Volume: 45, Issue:2

    Topics: Amygdala; Animals; Aspartic Acid; Cats; Chromatography, High Pressure Liquid; Electroencephalography; Epilepsy; Evoked Potentials; Glutamates; Glutamic Acid; Kindling, Neurologic; Seizures

1991
High-performance liquid chromatographic determination of selected amino acids in rat brain by precolumn derivatization with phenylisothiocyanate.
    Journal of chromatography, 1990, Mar-09, Volume: 503, Issue:1

    Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Isothiocyanates; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Serine; Thiocyanates

1990
Increased aspartic acid release from the iron-induced epileptogenic focus.
    Epilepsy research, 1990, Volume: 6, Issue:3

    Topics: Acute Disease; Animals; Aspartic Acid; Chronic Disease; Epilepsy; Glutamates; Glutamic Acid; Iron; Male; Rats; Rats, Inbred Strains

1990
Cyclic AMP levels in slices of epileptic cortex of the rat: effects of glutamate and 3-isobutyl-1-methylxanthine.
    Acta medica Okayama, 1986, Volume: 40, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cerebral Cortex; Cyclic AMP; Electroencephalography; Epilepsy; Ferrous Compounds; Glutamates; Glutamic Acid; Male; Rats; Rats, Inbred Strains; Theophylline

1986
Mechanisms of action of new antiepileptic drugs.
    Epilepsia, 1989, Volume: 30 Suppl 1

    Topics: Acetamides; Acetates; Amines; Aminocaproates; Aminopyridines; Anti-Anxiety Agents; Anticonvulsants; Aspartic Acid; Benzodiazepines; Benzodiazepinones; Clobazam; Cyclohexanecarboxylic Acids; Dibenzocycloheptenes; Dizocilpine Maleate; Epilepsy; Felbamate; Flumazenil; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Imidazoles; Lamotrigine; Phenylcarbamates; Propylene Glycols; Receptors, GABA-A; Triazines; Vigabatrin

1989
Glutamate, without GABA antagonists, induces synchronized discharges in intact hippocampus via NMDA receptors.
    Brain research, 1989, Sep-25, Volume: 498, Issue:1

    Topics: Action Potentials; Animals; Dibenzocycloheptenes; Dizocilpine Maleate; Electric Stimulation; Epilepsy; Glutamates; Glutamic Acid; Hippocampus; Male; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter

1989
CGP 31358 binds to a site on the NMDA receptor that is coupled to both the transmitter recognition site and the channel domain.
    Neuroscience letters, 1989, Dec-15, Volume: 107, Issue:1-3

    Topics: Animals; Anticonvulsants; Binding, Competitive; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Epilepsy; Glutamates; Glutamic Acid; Mice; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Subcellular Fractions; Triazoles

1989
Putative amino acid transmitters in lumbar cerebrospinal fluid of patients with histologically verified Alzheimer's dementia.
    Journal of neurology, neurosurgery, and psychiatry, 1985, Volume: 48, Issue:5

    Topics: Adult; Aged; Alzheimer Disease; Amino Acids; Aspartic Acid; Dementia; Epilepsy; Female; Glutamates; Glutamic Acid; Glycine; Humans; Male; Middle Aged; Neurotransmitter Agents

1985
"Epileptic" brain damage is replicated qualitatively in the rat hippocampus by central injection of glutamate or aspartate but not by GABA or acetylcholine.
    Brain research bulletin, 1985, Volume: 15, Issue:1

    Topics: Acetylcholine; Animals; Aspartic Acid; Brain; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamates; Glutamic Acid; Hippocampus; Immunoenzyme Techniques; Injections, Intraventricular; Male; Motor Activity; Nerve Degeneration; Rats; Rats, Inbred Strains; Time Factors

1985
Neuronal sensitivity to GABA and glutamate in generalized epilepsy with spike and wave discharges.
    Experimental neurology, 1986, Volume: 92, Issue:1

    Topics: Animals; Brain; Cats; Cerebral Cortex; Electrophysiology; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Neurons; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter

1986
Differential changes in the content of amino acid neurotransmitters in discrete regions of the rat brain prior to the onset and during the course of homocysteine-induced seizures.
    Journal of neurochemistry, 1986, Volume: 46, Issue:5

    Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Corpus Striatum; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Hippocampus; Homocysteine; Hypothalamus; Inferior Colliculi; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Serine; Substantia Nigra; Taurine; Tissue Distribution

1986
Ischemic CA-1 pyramidal cell loss is prevented by preischemic colchicine destruction of dentate gyrus granule cells.
    Brain research, 1986, Jul-09, Volume: 377, Issue:2

    Topics: Animals; Colchicine; Epilepsy; Glutamates; Glutamic Acid; Hippocampus; Ischemic Attack, Transient; Male; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Synaptic Transmission

1986
Relationship of glutamic acid and zinc to kindling of the rat amygdala: afferent transmitter systems and excitability in a model of epilepsy.
    Advances in experimental medicine and biology, 1986, Volume: 203

    Topics: Action Potentials; Afferent Pathways; Amygdala; Animals; Cholinergic Fibers; Epilepsy; Glutamates; Glutamic Acid; Kindling, Neurologic; Neurotransmitter Agents; Nucleotides, Cyclic; Synaptic Transmission; Zinc

1986
Seizures and brain damage: are excitatory amino acids involved?
    Advances in experimental medicine and biology, 1986, Volume: 203

    Topics: Action Potentials; Amino Acids; Animals; Brain; Epilepsy; Glutamates; Glutamic Acid; Hippocampus; Nerve Degeneration; Neurotransmitter Agents; Quinolinic Acid; Quinolinic Acids; Seizures; Synaptic Transmission

1986
Contributions of basic neurochemistry towards a novel concept of epilepsy.
    Neurochemical research, 1987, Volume: 12, Issue:2

    Topics: Animals; Brain; Cats; Epilepsy; Glutamates; Glutamic Acid; Humans; Models, Neurological; Neuroglia; Rats

1987
Redistribution of transmitter amino acids in rat hippocampus and cerebellum during seizures induced by L-allylglycine and bicuculline: an immunocytochemical study with antisera against conjugated GABA, glutamate and aspartate.
    Neuroscience, 1987, Volume: 22, Issue:1

    Topics: Allylglycine; Animals; Aspartic Acid; Bicuculline; Cerebellum; Epilepsy; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Hippocampus; Immunoenzyme Techniques; Male; Neurons; Rats; Rats, Inbred Strains; Synaptic Transmission

1987
Neurotransmitter amino acids in epilepsy.
    Electroencephalography and clinical neurophysiology. Supplement, 1987, Volume: 39

    Topics: Amino Acids; Aspartic Acid; Epilepsy; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Neurotransmitter Agents; Receptors, GABA-A; Receptors, Neurotransmitter

1987
[Modern aspects of epilepsy research and its application].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1987, Volume: 39, Issue:11

    Topics: Anticonvulsants; Brain; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Neuropeptides; Receptors, Neurotransmitter; Research

1987
[Epileptic seizure model utilizing additive effects of excitatory amino acids].
    No to shinkei = Brain and nerve, 1988, Volume: 40, Issue:8

    Topics: Amino Acids; Amygdala; Animals; Aspartic Acid; Drug Synergism; Electroencephalography; Epilepsy; Glutamates; Glutamic Acid; Injections; Kindling, Neurologic; Male; Rats; Rats, Inbred Strains

1988