glutamic acid has been researched along with Amyloid Deposits in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.00) | 18.2507 |
| 2000's | 11 (44.00) | 29.6817 |
| 2010's | 12 (48.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen-Engerer, HJ; Frosch, MP; Hong, W; Konnerth, A; Sakmann, B; Simon, MM; Unger, F; Walsh, DM; Zott, B | 1 |
| Buchanan, RA; Consoli, DC; Dixit, S; Harrison, FE; May, JM; Nobis, WP; Tienda, AA; Wilcox, JM | 1 |
| Dolly, JO; Ntziachristos, V; O'Leary, VB; Ovsepian, SV; Zaborszky, L | 1 |
| Baek, SH; Jo, DG; Jung, WR; Kim, HG; Kim, KL; Park, DI; Park, JS; Shin, MK | 1 |
| Akai, T; Iizuka, H; Ishigaki, Y; Kato, N; Liu, X; Shui, Y; Tajima, N; Uchiumi, O; Wang, M; Zou, J | 1 |
| Gerenu, G; Gil-Bea, FJ; Ramirez, MJ; Rodriguez-Perdigon, M; Solas, M; Tordera, RM | 1 |
| Breitner, JC; Cavanagh, C; Krantic, S; Nguyen, HB; Quirion, R; Tse, YC; Wong, TP | 1 |
| Blazquez-Llorca, L; Freitag, SV; Herms, J; Ovsepian, SV; Rodrigues, EF | 1 |
| Hefendehl, JK; Ko, RW; LeDue, J; MacVicar, BA; Mahler, J; Murphy, TH | 1 |
| Casali, B; Jay, TR; Lamb, R; Landreth, GE; Malm, T; Mariani, MM; Medarametla, L; Neilson, L | 1 |
| Barger, SW; DeWall, KM; Griffin, WS; Liu, L; Mrak, RE | 1 |
| Hartmann, J; Kiewert, C; Klein, J | 1 |
| Malavolta, L; Nakaie, CR | 1 |
| Kraemer, BC; Leverenz, JB; McMillan, PJ; Raskind, M; Robinson, L; Schellenberg, G | 1 |
| Del Vecchio, R; Gold, L; Jolas, T; Priestley, T; Wong, G; Zhang, Q; Zhang, XS | 1 |
| Anderson, VE; Atwood, CS; Carey, PR; Dong, J; Perry, G; Siedlak, SL; Smith, MA | 1 |
| Bell, KF; Cuello, AC; de Kort, GJ; Ribeiro-da-Silva, A; Shigemoto, R; Steggerda, S | 1 |
| Bobich, JA; Campbell, A; Zheng, Q | 1 |
| Jacobsen, H; Künnecke, B; Loetscher, H; Metzger, F; Ozmen, L; Richards, JG; Steiner, G; von Kienlin, M | 1 |
| Carrì, MT; Celsi, F; Cotman, CW; Nordberg, A; Ottersen, OP; Svedberg, M; Torp, R; Unger, C | 1 |
| Arzberger, T; Bartl, J; Grünblatt, E; Jacob, CP; Koutsilieri, E; Neuen-Jacob, E; Ravid, R; Riederer, P; Roggendorf, W; Zander, N | 1 |
| Bell, KF; Bennett, DA; Cuello, AC | 1 |
| Banerjee, P; Glennon, J; Goldsteins, G; Ihalainen, J; Iivonen, H; Keksa-Goldsteine, V; Koistinaho, J; Leguit, N; Malm, T; Matilainen, O; Minkeviciene, R; Tanila, H | 1 |
| Barrow, CJ; He, W | 1 |
| Robinson, SR | 1 |
1 review(s) available for glutamic acid and Amyloid Deposits
| Article | Year |
|---|---|
Amyloid Plaques of Alzheimer's Disease as Hotspots of Glutamatergic Activity.
Topics: Alzheimer Disease; Animals; Axons; Brain; Glutamic Acid; Humans; Plaque, Amyloid; Presynaptic Terminals | 2019 |
24 other study(ies) available for glutamic acid and Amyloid Deposits
| Article | Year |
|---|---|
A vicious cycle of β amyloid-dependent neuronal hyperactivation.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; CA1 Region, Hippocampal; Disease Models, Animal; Glutamic Acid; Humans; Long-Term Potentiation; Mice; Neurons; Plaque, Amyloid; Protein Multimerization | 2019 |
Altered synaptic glutamate homeostasis contributes to cognitive decline in young APP/PSEN1 mice.
Topics: Amyloid beta-Protein Precursor; Animals; Cognitive Dysfunction; Electroencephalography; Epilepsy; Female; Glutamic Acid; Hippocampus; Homeostasis; Kainic Acid; Long-Term Potentiation; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Plaque, Amyloid; Presenilin-1 | 2021 |
Neuropep-1 ameliorates learning and memory deficits in an Alzheimer's disease mouse model, increases brain-derived neurotrophic factor expression in the brain, and causes reduction of amyloid beta plaques.
Topics: 1-Methyl-4-phenylpyridinium; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Brain-Derived Neurotrophic Factor; Cell Death; Cells, Cultured; Disease Models, Animal; Glutamic Acid; Humans; Learning; Memory; Mice; Molecular Targeted Therapy; Neurons; Neuroprotective Agents; Oligopeptides; Peptide Fragments; Plaque, Amyloid | 2014 |
Learning impairment by minimal cortical injury in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain Injuries; Disease Models, Animal; Glutamic Acid; Hippocampus; Large-Conductance Calcium-Activated Potassium Channels; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Neurotoxins; Parietal Lobe; Peptide Fragments; Plaque, Amyloid | 2016 |
Down-regulation of glutamatergic terminals (VGLUT1) driven by Aβ in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cells, Cultured; Disease Models, Animal; Glutamic Acid; Humans; Mice, Inbred C57BL; Mice, Transgenic; Neuronal Plasticity; Neurons; Plaque, Amyloid; Receptors, N-Methyl-D-Aspartate; Vesicular Glutamate Transport Protein 1 | 2016 |
Inhibiting tumor necrosis factor-α before amyloidosis prevents synaptic deficits in an Alzheimer's disease model.
Topics: Alzheimer Disease; Animals; Disease Models, Animal; Glutamic Acid; Hippocampus; Mice, Transgenic; Molecular Targeted Therapy; Neuronal Plasticity; Plaque, Amyloid; Synapses; Synaptic Transmission; Tumor Necrosis Factor-alpha | 2016 |
Ambient Glutamate Promotes Paroxysmal Hyperactivity in Cortical Pyramidal Neurons at Amyloid Plaques via Presynaptic mGluR1 Receptors.
Topics: Animals; Benzoates; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; Mice, Inbred C57BL; Neurons; Plaque, Amyloid; Pyramidal Cells; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Synaptic Transmission | 2017 |
Mapping synaptic glutamate transporter dysfunction in vivo to regions surrounding Aβ plaques by iGluSnFR two-photon imaging.
Topics: Amino Acid Transport System X-AG; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Ceftriaxone; Diagnostic Imaging; Glutamic Acid; Mice; Mice, Transgenic; Plaque, Amyloid | 2016 |
Neuronally-directed effects of RXR activation in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Bexarotene; Biomarkers; Cell Survival; Cytokines; Disease Models, Animal; Female; Gliosis; Glutamic Acid; Habituation, Psychophysiologic; Hippocampus; Inflammation; Male; Membrane Transport Proteins; Memory; Mice, Transgenic; Neurons; Neurotoxins; Olfactory Bulb; Plaque, Amyloid; Receptors, LDL; Retinoid X Receptors; Synapses; Tetrahydronaphthalenes | 2017 |
Relationships between expression of apolipoprotein E and beta-amyloid precursor protein are altered in proximity to Alzheimer beta-amyloid plaques: potential explanations from cell culture studies.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Apolipoproteins E; Brain; Cells, Cultured; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Glutamic Acid; Humans; Male; Middle Aged; Neocortex; Neurons; Plaque, Amyloid; Rats; RNA, Small Interfering | 2008 |
Neurotransmitters and energy metabolites in amyloid-bearing APP(SWE)xPSEN1dE9 Mouse Brain.
Topics: Acetylcholine; Amyloid; Animals; Brain; Cerebral Cortex; Choline; Cholinesterases; Energy Metabolism; Glucose; Glutamic Acid; Glycerol; Hippocampus; Lactic Acid; Male; Mice; Mice, Transgenic; Motor Activity; Neurotransmitter Agents; Plaque, Amyloid; Scopolamine; Synaptosomes | 2010 |
Comparative fibril formation of analogs corresponding to the (12-24) segment of the β-amyloid peptide.
Topics: Amyloid beta-Peptides; Chromatography, High Pressure Liquid; Glutamic Acid; Glutamine; Humans; Nephelometry and Turbidimetry; Peptide Fragments; Plaque, Amyloid; Spectrometry, Fluorescence | 2011 |
Truncation of tau at E391 promotes early pathologic changes in transgenic mice.
Topics: Adenosine Triphosphatases; Alzheimer Disease; Animals; Brain; Cation Transport Proteins; Copper-Transporting ATPases; Disease Models, Animal; Gene Expression Regulation; Glutamic Acid; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neurons; Phosphorylation; Plaque, Amyloid; tau Proteins | 2011 |
Long-term potentiation is increased in the CA1 area of the hippocampus of APP(swe/ind) CRND8 mice.
Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Electrophysiology; Excitatory Postsynaptic Potentials; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; Genotype; Glutamic Acid; Hippocampus; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neural Inhibition; Neuronal Plasticity; Plaque, Amyloid; Synaptic Transmission | 2002 |
Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence.
Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Aspartic Acid; Binding Sites; Brain Chemistry; Cerebral Cortex; Copper; Female; Glutamic Acid; Humans; Iron; Metals, Heavy; Methionine; Microscopy; Oxidation-Reduction; Plaque, Amyloid; Protein Structure, Secondary; Spectrum Analysis, Raman; Tyrosine; Zinc | 2003 |
Structural involvement of the glutamatergic presynaptic boutons in a transgenic mouse model expressing early onset amyloid pathology.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cerebral Cortex; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Image Processing, Computer-Assisted; Immunohistochemistry; Mice; Mice, Transgenic; Neurites; Neuropil; Plaque, Amyloid; Presynaptic Terminals | 2003 |
Incubation of nerve endings with a physiological concentration of Abeta1-42 activates CaV2.2(N-Type)-voltage operated calcium channels and acutely increases glutamate and noradrenaline release.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cerebral Cortex; Female; Glutamic Acid; Hippocampus; Male; Nerve Degeneration; Nerve Endings; Nerve Tissue Proteins; Norepinephrine; Peptide Fragments; Plaque, Amyloid; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species | 2004 |
Altered metabolic profile in the frontal cortex of PS2APP transgenic mice, monitored throughout their life span.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Biomarkers; Disease Models, Animal; Disease Progression; Energy Metabolism; Female; Frontal Lobe; Glutamic Acid; Magnetic Resonance Imaging; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Plaque, Amyloid; Presenilin-2; Spectrum Analysis | 2005 |
Beta-amyloid causes downregulation of calcineurin in neurons through induction of oxidative stress.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Calcineurin; Cell Line; Cricetinae; Down-Regulation; Female; Glutamic Acid; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Immunoelectron; Mossy Fibers, Hippocampal; Neurons; Oxidative Stress; Plaque, Amyloid; Presynaptic Terminals; Superoxide Dismutase; Superoxide Dismutase-1 | 2007 |
Alterations in expression of glutamatergic transporters and receptors in sporadic Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Female; Gene Expression Regulation; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Plaque, Amyloid; Receptors, Glutamate; Reference Values; Reverse Transcriptase Polymerase Chain Reaction | 2007 |
Paradoxical upregulation of glutamatergic presynaptic boutons during mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Cognition Disorders; Cohort Studies; Disease Progression; Female; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Male; Neurons; Neuropsychological Tests; Plaque, Amyloid; Prefrontal Cortex; Presynaptic Terminals; Severity of Illness Index; Up-Regulation | 2007 |
Age-related decrease in stimulated glutamate release and vesicular glutamate transporters in APP/PS1 transgenic and wild-type mice.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Astrocytes; Brain; Disease Models, Animal; Down-Regulation; Glial Fibrillary Acidic Protein; Gliosis; Glutamic Acid; Humans; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Plaque, Amyloid; Presenilin-1; Synaptic Transmission; Vesicular Glutamate Transport Protein 1 | 2008 |
The A beta 3-pyroglutamyl and 11-pyroglutamyl peptides found in senile plaque have greater beta-sheet forming and aggregation propensities in vitro than full-length A beta.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Micelles; Molecular Sequence Data; Peptide Fragments; Plaque, Amyloid; Protein Structure, Secondary; Sodium Dodecyl Sulfate; Solutions | 1999 |
Changes in the cellular distribution of glutamine synthetase in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Astrocytes; Capillaries; Cell Size; Cerebral Cortex; Down-Regulation; Glial Fibrillary Acidic Protein; Glutamate-Ammonia Ligase; Glutamic Acid; Humans; Immunohistochemistry; Middle Aged; Neurites; Neurons; Plaque, Amyloid; Presynaptic Terminals | 2001 |