glutamic acid has been researched along with Alloxan Diabetes in 92 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (9.78) | 18.7374 |
| 1990's | 10 (10.87) | 18.2507 |
| 2000's | 29 (31.52) | 29.6817 |
| 2010's | 37 (40.22) | 24.3611 |
| 2020's | 7 (7.61) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Q; Liu, C; Wang, S; Wu, Z; Yang, Z; Zhang, T | 1 |
| Caramelo, B; Castelhano, J; Castelo-Branco, M; Manadas, B; Martins, J; Matafome, P; Monteiro-Alfredo, T; Sereno, J | 1 |
| Azarbayjani, MA; Peeri, M; Shekarchian, M | 1 |
| Huang, L; Li, J; Wang, C; Zhao, S | 1 |
| Alolayan, SO; Alomar, SY; Atef, H; El-Shafey, M; Elaskary, AA; Eldosoky, M; Elhawary, R; Elkazaz, AY; Gabr, AM; M Barakat, B; Mohamed, AS; Salih, MAK; Youssef, AM; Zaitone, SA | 1 |
| Abo El Gheit, RE; Badawi, GA; Badr, SM; El-Saka, MH; Emam, MN; Madi, NM; Soliman, NA | 1 |
| Ikeda, H; Kamei, J; Yamamoto, S | 1 |
| Lin, B; Lu, Y; Zhong, J | 1 |
| Guo, Y; Sun, Z; Wang, H; Wang, J; Wang, Y | 1 |
| Li, Y; Liu, X; Patel, KP; Zheng, H | 1 |
| Chakraborty, S; Kannan, R; Lonchin, S; Muthuvijayan, V; Ramachandran, B; Thangavel, P | 1 |
| Batassini, C; da Silva, VF; Federhen, BC; Galland, F; Gonçalves, CA; Hansen, F; Leite, MC; Nardin, P; Zanotto, C | 1 |
| Li, Q; Liao, XY; Liu, XJ; Liu, YD; Lu, D; Mu, ZH; Qi, YH; Qian, ZY; Wan, Q; Wang, Q; Wang, X; Yang, ZH; Zhang, MY; Zhu, R; Zou, YY | 1 |
| Alhomida, AS; LaNoue, KF; Ola, MS | 1 |
| Ali, AA; Ali, SA; Dessouki, AA; Zaitone, SA | 1 |
| Kroes, RA; Lau, JC; Linsenmeier, RA; Moskal, JR | 1 |
| Li, H; Li, W; Wang, P | 1 |
| Sickmann, HM; Waagepetersen, HS | 1 |
| Chen, WJ; Dong, MJ; Gao, HC; Hu, ZL; Su, Y; Wang, N; Yang, YJ; Zhao, LC; Zheng, YQ | 1 |
| Kong, Y; Li, Z; Liu, C; Liu, Y; Song, Y; Wang, H; Yang, J | 1 |
| Gao, F; Gu, L; Li, W; Lu, L; Sinha, D; Tian, H; Wang, F; Wang, J; Xu, G; Xu, GT; Xu, H; Xu, JY; Zhang, J | 1 |
| Cho, GJ; Cho, KM; Choi, WS; Goo, YM; Jung, S; Kang, SS; Kim, HJ; Kim, JY; Lee, DH; Roh, GS; Son, H | 1 |
| Bach, EC; Halmos, KC; Smith, BN | 1 |
| Ambrósio, AF; Castilho, Á; Hartveit, E; Veruki, ML | 1 |
| Bhattarai, JP; Cho, DH; Han, SK; Lee, JC; Nguyen, HT; Park, SJ | 1 |
| Gao, L; Huang, M; Lei, H; Zhang, H | 1 |
| Ain-Shoka, AA; Attia, AS; El-Sahar, AE; Safar, MM; Zaki, HF | 1 |
| Bradamante, V; Kelava, M; Konjevoda, P; Lovrić, J; Macan, M; Štambuk, N; Vrkić, N; Vukšić, A; Žunec, S | 1 |
| Calaza, KC; Carpi-Santos, R; Cossenza, M; Ferreira, MJ; Giestal-de-Araujo, E; Pereira Netto, AD; Ventura, ALM | 1 |
| Dong, B; Du, Y; Gao, H; Li, X; Lin, X; Yang, Y; Zhao, L; Zheng, H; Zheng, Y | 1 |
| Asashima, M; Fujimaki, S; Hidaka, R; Kuwabara, T; Wakabayashi, T | 1 |
| Boychuk, CR; Smith, BN | 1 |
| Achaval, M; Bagatini, PB; Bobermin, L; de Senna, PN; do Nascimento, PS; Galland, F; Gonçalves, CA; Nardin, P; Tramontina, AC; Xavier, LL | 1 |
| Cheng, JK; Hou, SY; Huang, YH; Lin, CR; Wu, CH | 1 |
| Satoh, E; Takahashi, A | 1 |
| Agarwal, N; Kanamori, A; Nagai-Kusuhara, A; Nakamura, M; Nakanishi, Y; Negi, A; Tatsumi, Y | 1 |
| Antony, S; Joseph, A; Paulose, CS | 1 |
| Fink, BD; Herlein, JA; O'Malley, Y; Sivitz, WI | 1 |
| Kade, IJ; Nogueira, CW; Rocha, JB | 1 |
| Hawkins, RA | 1 |
| Clarke, KG; Gil, DW; Kusari, J; Padillo, E; Zhou, SX | 1 |
| Dejoseph, MR; Fernstrom, JD; Hawkins, RA; Mokashi, A; Viña, JR | 1 |
| Braden, TD; Coleman, ES; Dennis, JC; Judd, RL; Posner, P | 1 |
| Ghazi-Khansari, M; Jaberi, E; Mohammadi-Farani, A; Sahebgharani, M; Sepehrizadeh, Z | 1 |
| Chae, SJ; Choi, S; Choi, SK; Kang, SW; Lee, GJ; Lee, SH; Park, HK; Yin, CS | 1 |
| Chu, Q; Lei, X; Wang, Q; Xu, GT; Ye, W; Zhang, J; Zhang, Y | 1 |
| Gowda, K; LaNoue, KF; Zinnanti, WJ | 1 |
| Fanne, RA; Heyman, SN; Higazi, AA; Hijazi, N; Nassar, T | 1 |
| Alvarez-Bustamante, JA; Rendon, DA | 1 |
| Barger, SW; Fang, J; Jiang, H; Qu, J; Sun, L; Wu, B; Wu, S; Yin, G | 1 |
| Li, Q; Puro, DG | 1 |
| Puro, DG | 1 |
| Cheng, JT; Lin, MT; Liu, IM; Niu, CS | 1 |
| GAYER, J; KLINGMULLER, V | 1 |
| DOMJAN, G; FAZEKAS, A; JAKI, A | 1 |
| Lashin, O; Romani, A | 2 |
| Andrews, NA; Blake, R; Maneuf, YP; McKnight, AT | 1 |
| Ling, EA; Ng, YK; Zeng, XX | 1 |
| Fletcher, EL; Jobling, AI; Kalloniatis, M; Ward, MM | 1 |
| Dunbar, JC; Levy, J; Zhu, Z | 1 |
| Karmaker, S; Saha, TK; Sakurai, H; Yasui, H; Yoshikawa, Y | 1 |
| Calcutt, NA; Ceseña, R; Glennon, JC; Malmberg, AB; O'Connor, WT | 1 |
| Bean, L; Monaghan, DT; Patel, KP; Zheng, H | 1 |
| Chen, F; Chen, K; Mi, M; Tang, Y; Wang, J; Wei, N; Xu, H; Xu, Z; Yu, X; Zeng, K; Zhang, Q; Zhu, J | 1 |
| Joseph, A; Paulose, CS; Robinson, R | 1 |
| Bringmann, A; Pannicke, T; Reichenbach, A; Wiedemann, P; Wurm, A | 1 |
| Gu, Q; Wang, W; Xu, X; Zhu, B | 1 |
| Bringer, J; Grodsky, GM; Heldt, A | 1 |
| Lindsay, DB | 1 |
| Engerman, RL; Kern, TS | 1 |
| Brosnan, JT; Ewart, HS; Squires, SA | 1 |
| Giroix, MH; Malaisse, WJ; Sener, A; Zhang, TM | 1 |
| Salceda, R; Vilchis, C | 1 |
| Malaisse, WJ; Malaisse-Lagae, F; Valverde, I; Vicent, D; Villanueva-Peñacarrillo, ML | 1 |
| Barber, AJ; Dice, C; Lieth, E; Ratz, MJ; Strother, JM; Tanase, D; Xu, B | 1 |
| Beylot, M; Large, V | 1 |
| Antonetti, DA; LaNoue, KF; Lieth, E; Ratz, M | 1 |
| Diaz, FG; Guyot, LL; O'Regan, MH; Phillis, JW; Song, D | 2 |
| Funakoshi, A; Ishida, J; Kono, A; Maetani, M; Miyasaka, K; Shimazoe, T; Watanabe, S; Yakabe, T; Yamaguchi, M | 1 |
| Case, GL; Engerman, RL; Kern, TS; Kowluru, RA | 1 |
| Lang, HJ; Obrosova, IG; Stevens, MJ | 1 |
| Watford, M | 1 |
| Hundal, HS; Low, SY; Pogson, CI; Rennie, MJ; Taylor, PM | 2 |
| Aoki, T; Hitosugi, H; Iwamoto, Y; Kamei, J; Kasuya, Y | 1 |
| Field, CJ; Marliss, EB; Wu, GY | 1 |
| Higgins, ES; Loria, RM; Rogers, KS | 1 |
| Chomatas, H; Iakovou, D; Linardou, A; Palaiologos, G; Philippidis, H | 1 |
| Ardawi, MS | 1 |
| Galanopoulos, E; Lellos, V; Palaiologos, G; Papadakis, M; Philippidis, H | 1 |
2 review(s) available for glutamic acid and Alloxan Diabetes
| Article | Year |
|---|---|
Effects of diabetes on brain metabolism--is brain glycogen a significant player?
Topics: Animals; Astrocytes; Biological Transport; Blood-Brain Barrier; Brain; Citric Acid Cycle; Diabetes Mellitus; Diabetes Mellitus, Experimental; Energy Metabolism; Glucose; Glutamic Acid; Glutamine; Glycogen; Glycolysis; Humans; Lactates; Models, Biological; Models, Neurological; Neurons; Rats | 2015 |
Stimulation of insulin release in vivo by the methyl esters of succinic acid and glutamic acid.
Topics: Animals; Diabetes Mellitus, Experimental; Glucose; Glutamic Acid; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Rats; Succinates | 1997 |
90 other study(ies) available for glutamic acid and Alloxan Diabetes
| Article | Year |
|---|---|
The dysfunction of mGluRIIs is involved in the disorder of hippocampal neural network in diabetic mice model.
Topics: Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Glutamic Acid; Glycogen Synthase Kinase 3 beta; Hippocampus; Male; Mice; Mice, Inbred C57BL; Neural Networks, Computer; Proto-Oncogene Proteins c-akt | 2022 |
Functional imaging and neurochemistry identify in vivo neuroprotection mechanisms counteracting excitotoxicity and neurovascular changes in the hippocampus and visual cortex of obese and type 2 diabetic animal models.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Models, Animal; Neurochemistry; Neuroprotection; Obesity; Rats; Visual Cortex | 2023 |
Physical activity in a swimming pool attenuates memory impairment by reducing glutamate and inflammatory cytokines and increasing BDNF in the brain of mice with type 2 diabetes.
Topics: Animals; Body Weight; Brain; Brain-Derived Neurotrophic Factor; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Glutamic Acid; Hippocampus; Insulin Resistance; Interleukin-6; Memory Disorders; Mice; Swimming; Swimming Pools; Tumor Necrosis Factor-alpha | 2023 |
Diabetic encephalopathy causes the imbalance of neural activities between hippocampal glutamatergic neurons and GABAergic neurons in mice.
Topics: Action Potentials; Animals; Brain Diseases; Diabetes Mellitus, Experimental; Excitatory Amino Acid Agents; GABAergic Neurons; Glutamic Acid; Hippocampus; Male; Mice; Mice, Inbred C57BL; Neural Inhibition; Neurons; Patch-Clamp Techniques; Streptozocin; Synaptic Transmission | 2020 |
Protective effect of metformin on rat diabetic retinopathy involves suppression of toll-like receptor 4/nuclear factor-k B expression and glutamate excitotoxicity.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Glutamic Acid; Hypoglycemic Agents; Male; Metformin; NF-kappa B; Oxidative Stress; Rats, Wistar; Retina; Signal Transduction; Streptozocin; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2021 |
Retinoprotective effect of agmatine in streptozotocin-induced diabetic rat model: avenues for vascular and neuronal protection : Agmatine in diabetic retinopathy.
Topics: Agmatine; Animals; Antioxidants; Blood Glucose; Caspase 3; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Excitatory Amino Acid Transporter 1; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glucose Transporter Type 1; Glutamate-Ammonia Ligase; Glutamic Acid; Hypoglycemic Agents; Male; Neuroprotective Agents; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type I; Oxidative Stress; Rats; Receptors, N-Methyl-D-Aspartate; Retina; Streptozocin; Treatment Outcome; Vascular Endothelial Growth Factor A | 2021 |
Increase in brain l-lactate enhances fear memory in diabetic mice: Involvement of glutamate neurons.
Topics: Amygdala; Animals; Anxiety; Brain; Diabetes Mellitus, Experimental; Excitatory Amino Acid Antagonists; Fear; Glutamic Acid; Hippocampus; Lactic Acid; Male; Memory; Mice; Neurons; Streptozocin | 2021 |
The Therapeutic Effect of Dexmedetomidine on Rat Diabetic Neuropathy Pain and the Mechanism.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Apoptosis; Cytokines; Dexmedetomidine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Glutamic Acid; Hyperalgesia; Inflammation; Interleukin-1beta; Male; Microglia; Pain Threshold; Rats, Sprague-Dawley; Spinal Cord; Tumor Necrosis Factor-alpha; Yohimbine | 2017 |
The role and mechanism of glutamic NMDA receptor in the mechanical hyperalgesia in diabetic rats.
Topics: Analgesics, Non-Narcotic; Animals; Cyclic AMP Response Element-Binding Protein; Diabetes Mellitus, Experimental; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hyperalgesia; Male; Pain Threshold; Phosphorylation; Posterior Horn Cells; Random Allocation; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Touch | 2017 |
A Hypothalamic Leptin-Glutamate Interaction in the Regulation of Sympathetic Nerve Activity.
Topics: Animals; Blood Pressure; Diabetes Mellitus, Experimental; Excitatory Amino Acid Antagonists; Gene Knockdown Techniques; Glutamic Acid; Heart Rate; Hypothalamus; Kidney; Leptin; Male; Microinjections; Rats; Rats, Sprague-Dawley; Receptors, Leptin; Receptors, N-Methyl-D-Aspartate; RNA, Small Interfering; Sympathetic Nervous System; Valine | 2017 |
Accelerated Healing of Diabetic Wounds Treated with L-Glutamic acid Loaded Hydrogels Through Enhanced Collagen Deposition and Angiogenesis: An In Vivo Study.
Topics: Animals; Biocompatible Materials; Collagen; Diabetes Mellitus, Experimental; Disease Models, Animal; Glutamic Acid; Hydrogels; Immunohistochemistry; Materials Testing; Neovascularization, Physiologic; Rats; Spectrum Analysis; Wound Healing | 2017 |
Glutamatergic Alterations in STZ-Induced Diabetic Rats Are Reversed by Exendin-4.
Topics: Animals; Astrocytes; Diabetes Mellitus, Experimental; Disease Models, Animal; Exenatide; Glutamic Acid; Glycation End Products, Advanced; Glycosylation; Hippocampus; Male; Phosphatidylinositol 3-Kinases; Pyruvaldehyde; Rats, Wistar; Receptor for Advanced Glycation End Products; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Streptozocin; Synaptic Transmission | 2019 |
Early intervention with gastrodin reduces striatal neurotoxicity in adult rats with experimentally‑induced diabetes mellitus.
Topics: Animals; Benzyl Alcohols; Biomarkers; Brain-Derived Neurotrophic Factor; Corpus Striatum; Diabetes Mellitus, Experimental; Gene Expression; Glucosides; Glutamic Acid; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Biological; Neurons; Rats; Receptor, trkB | 2019 |
Gabapentin Attenuates Oxidative Stress and Apoptosis in the Diabetic Rat Retina.
Topics: Amino Acids; Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Gabapentin; Glutamic Acid; Glutathione; Lipid Peroxidation; Oxidative Stress; Rats, Sprague-Dawley; Reactive Oxygen Species; Streptozocin; Transaminases | 2019 |
Pregabalin affords retinal neuroprotection in diabetic rats: Suppression of retinal glutamate, microglia cell expression and apoptotic cell death.
Topics: Analgesics; Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Gene Expression; Glial Fibrillary Acidic Protein; Glutamic Acid; Glutathione; Interleukin-1beta; Male; Microglia; Neuroprotection; Neuroprotective Agents; Oxidative Stress; Pregabalin; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Retina; Tumor Necrosis Factor-alpha | 2019 |
Diabetes changes expression of genes related to glutamate neurotransmission and transport in the Long-Evans rat retina.
Topics: Animals; Biological Transport; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Gene Expression Regulation; Glutamic Acid; Protein Subunits; Rats; Rats, Long-Evans; Receptors, Cell Surface; Retina; RNA, Messenger; Streptozocin; Synaptic Transmission; Transcriptome; Vascular Endothelial Growth Factor A | 2013 |
Upregulation of glutamatergic transmission in anterior cingulate cortex in the diabetic rats with neuropathic pain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Diabetes Mellitus, Experimental; Excitatory Postsynaptic Potentials; Glutamic Acid; Gyrus Cinguli; Hot Temperature; Hyperalgesia; Male; Neuralgia; Neurons; Patch-Clamp Techniques; Physical Stimulation; Protein Kinase C; Rats, Sprague-Dawley; Receptors, Glutamate; Streptozocin; Synaptic Transmission; Touch; Up-Regulation | 2014 |
Alteration of interaction between astrocytes and neurons in different stages of diabetes: a nuclear magnetic resonance study using [1-(13)C]glucose and [2-(13)C]acetate.
Topics: Acetates; Animals; Astrocytes; Brain; Carbon Isotopes; Diabetes Mellitus, Experimental; Glucose; Glutamic Acid; Magnetic Resonance Imaging; Male; Neurons; Rats, Sprague-Dawley | 2015 |
Insulin treatment prevents the increase in D-serine in hippocampal CA1 area of diabetic rats.
Topics: Animals; Behavior, Animal; CA1 Region, Hippocampal; Diabetes Mellitus, Experimental; Glutamic Acid; Insulin, Long-Acting; Long-Term Potentiation; Male; Maze Learning; Racemases and Epimerases; Rats; Rats, Sprague-Dawley; Serine | 2015 |
Erythropoietin exerts a neuroprotective function against glutamate neurotoxicity in experimental diabetic retina.
Topics: Amino Acid Transport System X-AG; Animals; Apoptosis Inducing Factor; Cell Death; Cell Line; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Erythropoietin; Excitatory Amino Acid Antagonists; Glutamate-Ammonia Ligase; Glutamic Acid; Intravitreal Injections; Male; Poly Adenosine Diphosphate Ribose; Rats; Rats, Sprague-Dawley; Receptors, Erythropoietin; Receptors, Glutamate; Retina | 2014 |
Type 1 diabetes alters astrocytic properties related with neurotransmitter supply, causing abnormal neuronal activities.
Topics: AMP-Activated Protein Kinases; Animals; Astrocytes; Blotting, Western; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glucose; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Hippocampus; Immunohistochemistry; Male; Mice, Inbred C57BL; Nerve Tissue Proteins; Prefrontal Cortex; Reactive Nitrogen Species; Reactive Oxygen Species | 2015 |
Enhanced NMDA receptor-mediated modulation of excitatory neurotransmission in the dorsal vagal complex of streptozotocin-treated, chronically hyperglycemic mice.
Topics: Animals; Diabetes Mellitus, Experimental; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Male; Mice; Mice, Obese; N-Methylaspartate; Pentanoic Acids; Receptors, N-Methyl-D-Aspartate; Streptozocin; Vagus Nerve | 2015 |
Disruption of a neural microcircuit in the rod pathway of the mammalian retina by diabetes mellitus.
Topics: Adamantane; Amacrine Cells; Animals; Calcium; Diabetes Mellitus, Experimental; Excitatory Postsynaptic Potentials; Female; gamma-Aminobutyric Acid; Glutamic Acid; Neural Pathways; Rats; Receptors, AMPA; Retinal Bipolar Cells; Retinal Rod Photoreceptor Cells; Up-Regulation | 2015 |
Enhanced GABA action on the substantia gelatinosa neurons of the medullary dorsal horn in the offspring of streptozotocin-injected mice.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes, Gestational; Diabetic Neuropathies; Facial Nerve Diseases; Facial Pain; Female; Fetal Development; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Growth Disorders; Male; Mice, Inbred ICR; Pregnancy; Pregnancy in Diabetics; Streptozocin; Substantia Gelatinosa; Synaptic Transmission; Trigeminal Caudal Nucleus; Up-Regulation | 2015 |
Region-specific cerebral metabolic alterations in streptozotocin-induced type 1 diabetic rats: an in vivo proton magnetic resonance spectroscopy study.
Topics: Animals; Aspartic Acid; Blood Glucose; Brain Chemistry; Corpus Striatum; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glutamic Acid; Hippocampus; Hypoglycemic Agents; Inositol; Insulin; Magnetic Resonance Spectroscopy; Neurons; Proton Magnetic Resonance Spectroscopy; Rats; Taurine; Visual Cortex | 2015 |
Neuroprotective effects of pioglitazone against transient cerebral ischemic reperfusion injury in diabetic rats: Modulation of antioxidant, anti-inflammatory, and anti-apoptotic biomarkers.
Topics: Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Brain Ischemia; Carotid Artery, Common; Cytokines; Diabetes Mellitus, Experimental; Glutamic Acid; Hippocampus; Male; Neuroprotective Agents; NF-kappa B; Oxidative Stress; Pioglitazone; Rats; Rats, Wistar; Reperfusion Injury; Signal Transduction; Thiazolidinediones | 2015 |
Effects of simvastatin on malondialdehyde level and esterase activity in plasma and tissue of normolipidemic rats.
Topics: Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Brain Ischemia; Carotid Artery, Common; Cytokines; Diabetes Mellitus, Experimental; Glutamic Acid; Hippocampus; Male; Neuroprotective Agents; NF-kappa B; Oxidative Stress; Pioglitazone; Rats; Rats, Wistar; Reperfusion Injury; Signal Transduction; Simvastatin; Thiazolidinediones | 2015 |
Early changes in system [Formula: see text] and glutathione in the retina of diabetic rats.
Topics: Animals; Animals, Newborn; Blotting, Western; Cell Death; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Glutamic Acid; Glutathione; Immunohistochemistry; Male; Oxidative Stress; Rats; Reactive Oxygen Species; Retina; Time Factors | 2016 |
Metabonomic profiles delineate potential role of glutamate-glutamine cycle in db/db mice with diabetes-associated cognitive decline.
Topics: Animals; Cognition; Diabetes Mellitus, Experimental; Discriminant Analysis; Glutamic Acid; Glutamine; Hippocampus; Immunohistochemistry; Least-Squares Analysis; Male; Maze Learning; Memory; Metabolome; Metabolomics; Mice, Inbred C57BL; Models, Biological; Proton Magnetic Resonance Spectroscopy; Tissue Extracts | 2016 |
Diabetes Impairs Wnt3 Protein-induced Neurogenesis in Olfactory Bulbs via Glutamate Transporter 1 Inhibition.
Topics: Animals; Astrocytes; Behavior, Animal; Biomarkers; Cell Differentiation; Diabetes Mellitus, Experimental; Down-Regulation; Excitatory Amino Acid Transporter 2; Glutamic Acid; Insulin; Male; Neural Stem Cells; Neurogenesis; Neurons; Neurotransmitter Agents; Olfactory Bulb; Oligodendroglia; Rats, Inbred F344; Signal Transduction; Wnt3 Protein | 2016 |
Glutamatergic drive facilitates synaptic inhibition of dorsal vagal motor neurons after experimentally induced diabetes in mice.
Topics: Animals; Diabetes Mellitus, Experimental; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Inhibitory Postsynaptic Potentials; Kynurenic Acid; Male; Mice; Miniature Postsynaptic Potentials; Neurons; Patch-Clamp Techniques; Receptors, Glutamate; Sodium Channel Blockers; Tetrodotoxin; Tissue Culture Techniques; Vagus Nerve | 2016 |
Physical exercise reverses spatial memory deficit and induces hippocampal astrocyte plasticity in diabetic rats.
Topics: Animals; Astrocytes; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Exercise Therapy; Glial Fibrillary Acidic Protein; Glutamate-Ammonia Ligase; Glutamic Acid; Glutathione; Hippocampus; Male; Memory Disorders; Neuronal Plasticity; Random Allocation; Rats, Wistar; Recognition, Psychology; Running; Spatial Memory | 2017 |
Pulsed radiofrequency attenuates diabetic neuropathic pain and suppresses formalin-evoked spinal glutamate release in rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Formaldehyde; Glutamic Acid; Male; Neuralgia; Pulsed Radiofrequency Treatment; Rats; Rats, Sprague-Dawley; Secretory Pathway | 2016 |
Experimental diabetes enhances Ca2+ mobilization and glutamate exocytosis in cerebral synaptosomes from mice.
Topics: Animals; Brain; Calcium; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Exocytosis; Glutamic Acid; Kinetics; Male; Mice; Mice, Inbred Strains; omega-Agatoxin IVA; Potassium; Synaptosomes | 2008 |
Nipradilol protects rat retinal ganglion cells from apoptosis induced by serum deprivation in vitro and by diabetes in vivo.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Apoptosis; Calcium; Caspase 3; Cell Line; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Dose-Response Relationship, Drug; Glutamic Acid; In Situ Nick-End Labeling; Male; Propanolamines; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; Serum; Vasodilator Agents | 2008 |
Increased glutamate receptor gene expression in the cerebral cortex of insulin induced hypoglycemic and streptozotocin-induced diabetic rats.
Topics: Analysis of Variance; Animals; Blood Glucose; Cerebral Cortex; Diabetes Mellitus, Experimental; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Glutamic Acid; Hypoglycemia; Insulin; Male; Protein Binding; Radioligand Assay; Rats; Rats, Wistar; Receptors, Glutamate; RNA, Messenger; Tritium | 2008 |
Superoxide and respiratory coupling in mitochondria of insulin-deficient diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Glutamic Acid; Glutathione; Heart; Insulin; Liver; Malates; Male; Membrane Potentials; Mitochondria, Heart; Mitochondria, Liver; Mitochondria, Muscle; Muscle, Skeletal; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Rotenone; Succinates; Superoxides | 2009 |
Diphenyl diselenide and streptozotocin did not alter cerebral glutamatergic and cholinergic systems but modulate antioxidant status and sodium pump in diabetic rats.
Topics: Acetylcholinesterase; Animals; Antioxidants; Ascorbic Acid; Behavior, Animal; Benzene Derivatives; Cerebral Cortex; Diabetes Mellitus, Experimental; Glutamic Acid; Glutathione; Male; Organoselenium Compounds; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Streptozocin; Thiobarbituric Acid Reactive Substances | 2009 |
The blood-brain barrier and glutamate.
Topics: Amino Acid Transport Systems; Animals; Biological Transport; Blood-Brain Barrier; Brain; Cerebrospinal Fluid; Diabetes Mellitus, Experimental; Endothelial Cells; Glutamic Acid; Glutamine; Insulin Resistance; Obesity; Rats; Tight Junctions | 2009 |
Inhibition of vitreoretinal VEGF elevation and blood-retinal barrier breakdown in streptozotocin-induced diabetic rats by brimonidine.
Topics: Adrenergic alpha-Agonists; Animals; Blood Glucose; Blood-Retinal Barrier; Blotting, Western; Brimonidine Tartrate; Capillary Permeability; Diabetes Mellitus, Experimental; Glutamic Acid; Infusion Pumps; Male; Quinoxalines; Rats; Rats, Inbred BN; Rats, Long-Evans; Retina; Vascular Endothelial Growth Factor A; Vitreous Body | 2010 |
Glutamate permeability at the blood-brain barrier in insulinopenic and insulin-resistant rats.
Topics: Animals; Blood-Brain Barrier; Brain Chemistry; Capillary Permeability; Diabetes Mellitus, Experimental; Diet; Energy Intake; Glutamic Acid; Insulin Resistance; Male; Obesity; Rats; Rats, Sprague-Dawley | 2010 |
Insulin treatment prevents diabetes-induced alterations in astrocyte glutamate uptake and GFAP content in rats at 4 and 8 weeks of diabetes duration.
Topics: Animals; Astrocytes; Blotting, Western; Cerebellum; Cerebral Cortex; Diabetes Mellitus, Experimental; Glial Fibrillary Acidic Protein; Glutamic Acid; Hippocampus; Hypoglycemic Agents; Immunohistochemistry; Insulin; Male; Rats; Rats, Wistar; Sodium; Time Factors | 2010 |
Diabetic thermal hyperalgesia: role of TRPV1 and CB1 receptors of periaqueductal gray.
Topics: Analgesia; Analgesics; Animals; Benzoxazines; Capsaicin; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Down-Regulation; gamma-Aminobutyric Acid; Glutamic Acid; Hyperalgesia; Male; Morpholines; Naphthalenes; Neural Inhibition; Neurons; Nociceptors; Periaqueductal Gray; Rats; Receptor, Cannabinoid, CB1; RNA, Messenger; TRPV Cation Channels; Up-Regulation | 2010 |
Potential neuroprotective effects of acupuncture stimulation on diabetes mellitus in a global ischemic rat model.
Topics: Acupuncture Therapy; Animals; Blood Glucose; Body Temperature; Brain Ischemia; Cerebrovascular Circulation; Craniotomy; Diabetes Mellitus, Experimental; Disease Models, Animal; Electroencephalography; Extracellular Space; Glutamic Acid; Male; Neck; Neuroprotective Agents; Rats; Streptozocin | 2010 |
Intravitreal injection of exendin-4 analogue protects retinal cells in early diabetic rats.
Topics: Animals; Blotting, Western; Cell Count; Cells, Cultured; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Electroretinography; Excitatory Amino Acid Transporter 1; Exenatide; Fluorescent Antibody Technique, Indirect; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glutamic Acid; Hypoglycemic Agents; Intravitreal Injections; Male; Microscopy, Fluorescence; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Glucagon; Retina; RNA, Messenger; Venoms | 2011 |
The influence of diabetes on glutamate metabolism in retinas.
Topics: Animals; Carbon Isotopes; Diabetes Mellitus, Experimental; Disease Models, Animal; Glutamic Acid; In Vitro Techniques; Male; Neuroglia; Neurons; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Retina; Time Factors; Transaminases | 2011 |
Insulin and glucagon share the same mechanism of neuroprotection in diabetic rats: role of glutamate.
Topics: Analysis of Variance; Animals; Blood Glucose; Brain; Diabetes Mellitus, Experimental; Glucagon; Glutamic Acid; Hypoglycemic Agents; Infarction, Middle Cerebral Artery; Insulin; Male; Neuroprotective Agents; Oxaloacetic Acid; Rats; Rats, Sprague-Dawley; Time Factors | 2011 |
Early hyperglycemia following alloxan administration in vivo is not associated with altered hepatic mitochondrial function: acceptable model for type 1 diabetes?
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Glutamic Acid; Hyperglycemia; Malates; Mitochondria, Liver; Mitochondrial Proton-Translocating ATPases; Oxidative Phosphorylation; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Succinic Acid | 2011 |
Overexpression of serine racemase in retina and overproduction of D-serine in eyes of streptozotocin-induced diabetic retinopathy.
Topics: Animals; Aqueous Humor; Blood Glucose; Body Weight; Cell Death; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Glutamic Acid; JNK Mitogen-Activated Protein Kinases; Racemases and Epimerases; Random Allocation; Rats; Rats, Sprague-Dawley; Retina; Serine; Streptozocin | 2011 |
Diabetes-induced dysfunction of the glutamate transporter in retinal Müller cells.
Topics: Amino Acid Transport System X-AG; Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Electrophysiology; Glutamic Acid; Microscopy, Electron, Scanning; Neuroglia; Oxidation-Reduction; Patch-Clamp Techniques; Rats; Rats, Long-Evans; Retina | 2002 |
Diabetes-induced dysfunction of retinal Müller cells.
Topics: Amino Acid Transport System X-AG; Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Electrophysiology; Glutamic Acid; Hyperglycemia; Neuroglia; Oxidative Stress; Patch-Clamp Techniques; Rats; Rats, Long-Evans | 2002 |
Role of striatal glutamate in heatstroke-induced damage in streptozotocin-induced diabetic rats.
Topics: Animals; Corpus Striatum; Diabetes Mellitus, Experimental; Excitatory Amino Acid Antagonists; Glutamic Acid; Heat Stroke; Hot Temperature; Insulin; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Survival Rate | 2003 |
[Studies on L(+)glutamic acid metabolism. III. Effects of L(+)glutamic acid administration on carbohydrate metabolism].
Topics: Animals; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus, Experimental; Glutamates; Glutamic Acid; Glycogen; Glycogenolysis; Liver; Pharmaceutical Preparations | 1955 |
[CHANGES IN THE GLUTAMIC-PYRUVIC ACID TRANSAMINASE AND GLUTAMIC ACID DEHYDRASE ACTIVITY OF THE RAT LIVER IN ALLOXAN DIABETES].
Topics: Alanine Transaminase; Animals; D-Alanine Transaminase; Diabetes Mellitus, Experimental; Glutamic Acid; Hydrocortisone; Insulin; Liver; Oxidoreductases; Pyruvic Acid; Rats; Research | 1963 |
Mitochondria respiration and susceptibility to ischemia-reperfusion injury in diabetic hearts.
Topics: Animals; Body Weight; Cell Respiration; Diabetes Mellitus, Experimental; Disease Susceptibility; Glutamic Acid; Heart; Hyperglycemia; Ketones; Male; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion Injury; Organ Size; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Sarcolemma; Succinic Acid | 2003 |
Reduction by gabapentin of K+-evoked release of [3H]-glutamate from the caudal trigeminal nucleus of the streptozotocin-treated rat.
Topics: Acetates; Amines; Animals; Blood Glucose; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Male; Pain; Pain Measurement; Physical Stimulation; Potassium; Rats; Trigeminal Nuclei | 2004 |
Expression of glutamate receptors and calcium-binding proteins in the retina of streptozotocin-induced diabetic rats.
Topics: Amacrine Cells; Animals; Calbindins; Calcium-Binding Proteins; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Glutamic Acid; Immunohistochemistry; Male; Nerve Degeneration; Neurons; Parvalbumins; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Ganglion Cells; S100 Calcium Binding Protein G; Synaptic Transmission; Up-Regulation | 2004 |
Hyperglycemia does not alter state 3 respiration in cardiac mitochondria from type-I diabetic rats.
Topics: Animals; Cell Respiration; Diabetes Mellitus, Experimental; Glutamic Acid; Hyperglycemia; Insulin; Male; Mitochondria, Heart; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Time Factors | 2004 |
Glutamate uptake in retinal glial cells during diabetes.
Topics: Amino Acid Transport System X-AG; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 4; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Male; Rats; Rats, Sprague-Dawley; Reference Values; Retina; Retinal Ganglion Cells; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Symporters | 2005 |
The effect of global brain ischemia in normal and diabetic animals: the influence of calcium channel blockers.
Topics: Adenosine Triphosphate; Animals; Brain Chemistry; Brain Ischemia; Calcium; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Felodipine; Glutamic Acid; Lactic Acid; Male; Rats; Rats, Wistar; Reperfusion Injury; Water | 2004 |
A novel drug delivery system for type 1 diabetes: insulin-mimetic vanadyl-poly(gamma-glutamic acid) complex.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Delivery Systems; Glutamic Acid; Hypoglycemic Agents; Insulin; Mice; Molecular Structure; Vanadium | 2006 |
Impaired formalin-evoked changes of spinal amino acid levels in diabetic rats.
Topics: Afferent Pathways; Amino Acids; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Down-Regulation; Extracellular Fluid; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hyperalgesia; Microdialysis; Neurons, Afferent; Nociceptors; Pain Measurement; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Nerve Roots; Up-Regulation | 2006 |
Regional variations in NMDA receptor downregulation in streptozotocin-diabetic rat brain.
Topics: Animals; Binding, Competitive; Brain; Brain Diseases, Metabolic; Cerebral Cortex; Diabetes Complications; Diabetes Mellitus, Experimental; Disease Models, Animal; Down-Regulation; Glucose; Glutamic Acid; Insulin; Male; Neurons; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tritium | 2006 |
Dietary taurine supplementation ameliorates diabetic retinopathy via anti-excitotoxicity of glutamate in streptozotocin-induced Sprague-Dawley rats.
Topics: Amino Acid Transport System X-AG; Animals; Blood Glucose; Blotting, Western; Body Weight; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Dietary Supplements; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Retina; Reverse Transcriptase Polymerase Chain Reaction; Taurine | 2008 |
Enhanced [3H] glutamate binding in the cerebellum of insulin-induced hypoglycaemic and streptozotocin-induced diabetic rats.
Topics: Animals; Binding Sites; Cerebellum; Diabetes Mellitus, Experimental; Glutamate Dehydrogenase; Glutamic Acid; Hypoglycemia; Insulin; Liver; Male; Protein Binding; Rats; Rats, Wistar; Receptors, Glutamate; Streptozocin; Tritium | 2007 |
Glial cell-derived glutamate mediates autocrine cell volume regulation in the retina: activation by VEGF.
Topics: Animals; Cell Size; Diabetes Mellitus, Experimental; Disease Models, Animal; Glutamic Acid; Humans; Male; Neuroglia; Neurons; Rats; Rats, Long-Evans; Rats, Wistar; Receptors, Glutamate; Receptors, Purinergic; Reperfusion Injury; Retina; Vascular Endothelial Growth Factors; Water | 2008 |
Erythropoietin protects retinal neurons and glial cells in early-stage streptozotocin-induced diabetic rats.
Topics: Animals; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Electroretinography; Erythropoietin; Glutamic Acid; Microscopy, Electron; Mitochondria; Neuroglia; Rats; Rats, Sprague-Dawley; Receptors, Erythropoietin; Recombinant Proteins; Retina; Retinal Ganglion Cells | 2008 |
Prevention of insulin aggregation by dicarboxylic amino acids during prolonged infusion.
Topics: Animals; Artificial Organs; Aspartic Acid; Cricetinae; Cricetulus; Diabetes Mellitus, Experimental; Drug Implants; Female; Glutamates; Glutamic Acid; Insulin; Islets of Langerhans; Macromolecular Substances; Male | 1981 |
Relationships between amino acid catabolism and protein anabolism in the ruminant.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cattle; Diabetes Mellitus, Experimental; Gluconeogenesis; Glutamates; Glutamic Acid; Leucine; Liver; Muscles; Proteins; Sheep | 1982 |
Abnormal amino acid concentrations in plasma and urine of experimentally diabetic dogs.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Arginine; Diabetes Mellitus, Experimental; Dogs; Female; Glutamates; Glutamic Acid; Histidine; Male; Phenylalanine; Renal Aminoacidurias; Tryptophan; Tyrosine | 1983 |
Hormonal control of hepatic glutaminase.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Experimental; Dietary Proteins; Endotoxins; Enzyme Activation; Enzyme Inhibitors; Ethers, Cyclic; Glucagon; Glutamic Acid; Glutaminase; Glutamine; Mitochondria, Liver; Okadaic Acid; Phosphates; Rats; Signal Transduction; Thionucleotides | 1995 |
Hexose metabolism in pancreatic islets UDP-glucose pyrophosphorylase activity.
Topics: Animals; Carbon Radioisotopes; Diabetes Mellitus, Experimental; Diphosphates; Female; Glutamic Acid; Hexoses; Islets of Langerhans; Liver; Rats; Rats, Inbred Strains; Rats, Wistar; Reference Values; Substrate Specificity; Uridine Diphosphate Glucose; UTP-Glucose-1-Phosphate Uridylyltransferase | 1994 |
Effect of diabetes on levels and uptake of putative amino acid neurotransmitters in rat retina and retinal pigment epithelium.
Topics: Analysis of Variance; Animals; Aspartic Acid; Diabetes Mellitus, Experimental; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Neurotransmitter Agents; Pigment Epithelium of Eye; Rats; Retina; Taurine | 1996 |
Glial reactivity and impaired glutamate metabolism in short-term experimental diabetic retinopathy. Penn State Retina Research Group.
Topics: Acute Disease; Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Glial Fibrillary Acidic Protein; Glutamic Acid; Immunoblotting; Immunohistochemistry; Neuroglia; Rats; Rats, Sprague-Dawley; Retina | 1998 |
Modifications of citric acid cycle activity and gluconeogenesis in streptozotocin-induced diabetes and effects of metformin.
Topics: Animals; Citric Acid Cycle; Diabetes Mellitus, Experimental; Gluconeogenesis; Glucose; Glutamic Acid; Hypoglycemic Agents; In Vitro Techniques; Lactic Acid; Liver; Male; Metformin; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Starvation; Streptozocin | 1999 |
Diabetes reduces glutamate oxidation and glutamine synthesis in the retina. The Penn State Retina Research Group.
Topics: Animals; Blotting, Western; Culture Techniques; Diabetes Mellitus, Experimental; Glutamic Acid; Glutamine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Retina; Time Factors | 2000 |
The effect of topical insulin on the release of excitotoxic and other amino acids from the rat cerebral cortex during streptozotocin-induced hyperglycemic ischemia.
Topics: Administration, Topical; Animals; Aspartic Acid; Blood Glucose; Brain Ischemia; Cerebral Cortex; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electroencephalography; Excitatory Amino Acids; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Hyperglycemia; Insulin; Lactic Acid; Male; Rats; Rats, Sprague-Dawley; Reperfusion; Taurine | 2000 |
Entrainment function in the suprachiasmatic nucleus of streptozotocin-induced diabetic rats.
Topics: 5-Hydroxytryptophan; Animals; Brain; Circadian Rhythm; Diabetes Mellitus, Experimental; Glutamic Acid; Hydroxyindoleacetic Acid; Male; Motor Activity; Rats; Rats, Wistar; Serotonin; Streptozocin; Suprachiasmatic Nucleus | 2000 |
The effect of streptozotocin-induced diabetes on the release of excitotoxic and other amino acids from the ischemic rat cerebral cortex.
Topics: Acute Disease; Amino Acids; Animals; Blood Glucose; Brain Ischemia; Cerebral Cortex; Chronic Disease; Diabetes Mellitus, Experimental; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Lactic Acid; Male; Neurotoxins; Rats; Rats, Sprague-Dawley; Reference Values; Reperfusion Injury | 2001 |
Retinal glutamate in diabetes and effect of antioxidants.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Glutamic Acid; Male; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Retina; Thiobarbituric Acid Reactive Substances | 2001 |
Diabetes-induced changes in retinal NAD-redox status: pharmacological modulation and implications for pathogenesis of diabetic retinopathy.
Topics: Adrenergic alpha-Antagonists; Ammonia; Animals; Antioxidants; Cell Fractionation; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fructose; Glucose; Glutamic Acid; Imidazoles; Imidazolidines; Ketoglutaric Acids; Lactic Acid; Male; Mitochondria; NAD; Oxidation-Reduction; Piperazines; Prazosin; Pyrimidines; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Retina; Sorbitol; Thioctic Acid | 2001 |
Net interorgan transport of L-glutamate in rats occurs via the plasma, not via erythrocytes.
Topics: Animals; Biological Transport; Caseins; Diabetes Mellitus, Experimental; Erythrocytes; Food Deprivation; Glutamic Acid; Male; Plasma; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2002 |
Transport of L-glutamine and L-glutamate across sinusoidal membranes of rat liver. Effects of starvation, diabetes and corticosteroid treatment.
Topics: Amino Acids; Animals; Biological Transport, Active; Carboxylic Acids; Cell Membrane; Cells, Cultured; Dexamethasone; Diabetes Mellitus, Experimental; Female; Glutamates; Glutamic Acid; Glutamine; Kinetics; Liver; Rats; Rats, Inbred Strains; Starvation; Streptozocin | 1992 |
Effects of morphine on responses of nociceptive ventrobasal thalamic neurons in diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Glutamates; Glutamic Acid; Injections, Intravenous; Injections, Spinal; Iontophoresis; Male; Morphine; Neurons; Nociceptors; Rats; Rats, Sprague-Dawley; Thalamic Nuclei | 1992 |
Elevated glutamine metabolism in splenocytes from spontaneously diabetic BB rats.
Topics: Adenosine Triphosphate; Ammonia; Animals; Aspartic Acid; Carbon Radioisotopes; Cells, Cultured; Diabetes Mellitus, Experimental; Female; Glutamates; Glutamic Acid; Glutamine; Kinetics; Lactates; Lymphocytes; Male; Pyruvates; Rats; Rats, Inbred BB; Spleen | 1991 |
Glutamate uptake in sinusoidal membrane vesicles isolated from rat liver: effects of streptozotocin diabetes.
Topics: Animals; Biological Transport, Active; Diabetes Mellitus, Experimental; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Kinetics; Liver; Membranes; Rats; Rats, Inbred Strains | 1990 |
Influence of genetic predisposition to diabetes and obesity on mitochondrial function.
Topics: Animals; Diabetes Mellitus, Experimental; Genotype; Glutamates; Glutamic Acid; Liver; Male; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Obesity; Organ Size; Oxidation-Reduction; Proteins; Succinates; Succinic Acid | 1986 |
Effects of branched chain amino acids, pyruvate, or ketone bodies on the free amino acid pool and release from brain cortex slices of normal and streptozotocin-diabetic rats.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Cerebral Cortex; Diabetes Mellitus, Experimental; Glucose; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Ketone Bodies; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1987 |
Glutamine and ketone-body metabolism in the gut of streptozotocin-diabetic rats.
Topics: Alanine; Ammonia; Animals; Blood Glucose; Cell Separation; Colon; Diabetes Mellitus, Experimental; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Insulin; Intestinal Mucosa; Intestines; Ketone Bodies; Male; Rats; Rats, Inbred Strains; Regional Blood Flow | 1988 |
Effects of fasting and diabetes on some enzymes and transport of glutamate in cortex slices or synaptosomes from rat brain.
Topics: Animals; Cerebral Cortex; Diabetes Mellitus, Experimental; Fasting; Glutamate Decarboxylase; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Glutaminase; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Synaptosomes | 1988 |