glutamic acid has been researched along with Allergic Encephalomyelitis in 54 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (1.85) | 18.2507 |
| 2000's | 14 (25.93) | 29.6817 |
| 2010's | 32 (59.26) | 24.3611 |
| 2020's | 7 (12.96) | 2.80 |
| Authors | Studies |
|---|---|
| Aharoni, R; Arnon, R; Chapman, J; Dori, A; Eilam, R; Lerner, S; Shavit-Stein, E | 1 |
| Cancela, L; Castañares, C; Cristiano, E; Falcon, C; Garcia-Keller, C; Lopez, PHH; Monferran, C; Moyano, AL; Palandri, A; Patrucco, L; Rojas, JI; Rozés-Salvador, V; Schnaar, RL; Vivinetto, AL | 1 |
| Bassi, MS; Bellingacci, L; Bruno, A; Buttari, F; Centonze, D; Di Filippo, M; Di Maio, A; Dolcetti, E; Errico, F; Finardi, A; Furlan, R; Galifi, G; Gilio, L; Mancini, A; Nuzzo, T; Usiello, A | 1 |
| Dąbrowska-Bouta, B; Sidoryk-Węgrzynowicz, M; Strużyńska, L; Sulkowski, G | 1 |
| Olivero, G; Pittaluga, A; Roggeri, A; Usai, C; Vanmierlo, T | 1 |
| Bar-Or, A; Bueno, M; Charabati, M; de Faria Junior, O; Drake, SS; Dumas, A; Fournier, AE; Galloway, DA; Juźwik, CA; Lécuyer, MA; Moore, C; Morquette, B; Paradis-Isler, N; Prat, A; Rambaldi, I; Vallières, L; Zandee, S; Zhang, Y | 1 |
| Adler, K; Bevensee, MO; Bingaman, AM; DeSilva, TM; Doyle, RE; Evonuk, KS; Min, B; Moseley, CE; Thornell, IM; Weaver, CT | 1 |
| Betz, AJ; Demuro, J; Drummond, G; Johns, LD; Little, C; Rotolo, RA | 1 |
| Bullitta, S; Centonze, D; De Vito, F; Fresegna, D; Gentile, A; Mandolesi, G; Musella, A; Rizzo, FR | 1 |
| Hattori, T; Hori, O; Ishii, H; Kitao, Y; Le, TM; Roboon, J; Ta, HM; Takarada-Iemata, M; Tamatani, T | 1 |
| Bertorelli, R; Bonfiglio, T; Di Cesare Mannelli, L; Feligioni, M; Ghelardini, C; Iannuzzi, F; Olivero, G; Pacini, A; Pittaluga, A; Summa, M; Vergassola, M | 1 |
| Acharjee, S; Benediktsson, A; Benoit, L; Bisht, K; Gomez, CD; Lee, B; Pittman, QJ; Sharkey, KA; Tremblay, ME; Verbeek, M | 1 |
| Bullitta, S; Centonze, D; De Vito, F; Di Sanza, C; Fresegna, D; Gentile, A; Grasselli, G; Haji, N; Mandolesi, G; Musella, A; Musumeci, G; Sepman, H; Strata, P | 1 |
| Casazza, S; Di Prisco, S; Merega, E; Milanese, M; Pistoia, V; Pittaluga, A; Raffaghello, L; Summa, M; Uccelli, A | 1 |
| Centonze, D; Fresegna, D; Gentile, A; Haji, N; Mandolesi, G; Matarese, G; Motta, C; Musella, A; Paolillo, A; Rossi, S; Sepman, H; Studer, V | 1 |
| Mohebiany, AN; Schneider, R | 1 |
| Kan, QC; Xu, YM; Zhang, GX; Zhang, S; Zhu, L | 1 |
| Centonze, D; Conrad, A; Fresegna, D; Gentile, A; Haji, N; Lutz, B; Maccarrone, M; Mandolesi, G; Musella, A; Sepman, H | 1 |
| Chanaday, NL; de Paul, AL; Degano, AL; Roth, GA; Torres, AI; Vilcaes, AA | 1 |
| Centonze, D; Gentile, A; Mandolesi, G; Musella, A | 1 |
| Dąbrowska-Bouta, B; Salińska, E; Strużyńska, L; Sulkowski, G | 1 |
| Bragoni, A; Centonze, D; Cordano, C; Kerlero de Rosbo, N; Mancardi, GL; Morando, S; Motta, C; Parodi, B; Rossi, S; Scannevin, RH; Uccelli, A; Usai, C; Wipke, BT | 1 |
| Chanaday, NL; Fernández Hurst, N; Roth, GA | 1 |
| Ahn, G; Bing, SJ; Cho, IH; Cho, J; Ha, D; Herath, KH; Jee, Y; Jo, SA; Kim, A; Kim, J; Yu, HS | 1 |
| Deenen, R; Faber, C; Herrmann, AM; Klotz, L; Köhrer, K; Limmer, A; Loser, K; Luger, TA; Meuth, SG; Mykicki, N; Schwab, N; Sparwasser, T; Wachsmuth, L; Wiendl, H | 1 |
| Bonanno, G; Bonfiglio, T; Di Cesare Mannelli, L; Di Prisco, S; Ghelardini, C; Grilli, M; Marchi, M; Merega, E; Milanese, M; Olivero, G; Padolecchia, C; Pittaluga, A | 1 |
| Furlan, G; Roth, GA; Vilcaes, AA | 1 |
| Doi, Y; Harada, Y; Hua, L; Kawanokuchi, J; Liang, J; Mizuno, T; Noda, M; Shijie, J; Sonobe, Y; Suzumura, A; Takeuchi, H; Yasuoka, S; Yawata, I; Zhou, Y | 1 |
| Bernardi, G; Cantarella, C; Cavasinni, F; Centonze, D; De Chiara, V; Furlan, R; Lo Giudice, T; Martino, G; Martorana, A; Mataluni, G; Musella, A; Muzio, L; Rossi, S | 1 |
| Bernardi, G; Centonze, D; Furlan, R; Martino, G; Muzio, L; Rossi, S | 1 |
| Dabrowska-Bouta, B; Kwiatkowska-Patzer, B; Struzyńska, L; Sulkowski, G | 1 |
| Kerr, BJ; Leighton, J; Miller, B; Olechowski, CJ; Parmar, A; Stephan, J; Tenorio, G; Tran, K | 1 |
| Bernardi, G; Cavasinni, F; Centonze, D; De Chiara, V; Furlan, R; Martino, G; Musella, A; Muzio, L; Rossi, S | 1 |
| Cavallero, A; Fedele, E; Marte, A; Morando, S; Raiteri, M; Uccelli, A | 1 |
| Battaglia, G; Bicciato, S; Bruno, V; Busceti, C; Di Marco, R; Fallarino, F; Fazio, F; Fioretti, MC; Grohmann, U; Nicoletti, F; Notartomaso, S; Puccetti, P; Vacca, C; Volpi, C | 1 |
| Bernardi, G; Cavasinni, F; Centonze, D; Cravatt, BF; De Chiara, V; Furlan, R; Lutz, B; Maccarrone, M; Martino, G; Motta, C; Musella, A; Muzio, L; Rossi, S; Studer, V | 1 |
| Barkhouse, DA; Castegna, A; Curtis, MT; Fabis-Pedrini, MJ; Hooper, DC; Kean, RB; Palmieri, F; Palmieri, L; Porcelli, V; Spera, I | 1 |
| Cid, MP; Roth, GA; Rupil, LL; Salvatierra, NA; Vilcaes, AA | 1 |
| Domercq, M; Matute, C; Pampliega, O; Rodríguez-Antigüedad, A; Soria, FN; Villoslada, P | 1 |
| Bernardi, G; Centonze, D; De Chiara, V; Furlan, R; Lo Giudice, T; Martino, G; Martorana, A; Motta, C; Musella, A; Rossi, S; Studer, V | 1 |
| Berman, NE; Buchheit, CL; LeVine, SM; Williams, R | 1 |
| Elbrønd-Bek, H; Jørgensen, SH; Kelly, NM; Weidner, MS; Wellejus, A | 1 |
| Centonze, D; De Chiara, V; Di Sanza, C; Errico, F; Fresegna, D; Furlan, R; Gentile, A; Grasselli, G; Haji, N; Loizzo, S; Mandolesi, G; Martino, G; Musella, A; Musumeci, G; Muzio, L; Rossi, S; Sepman, H; Usiello, A | 1 |
| Groom, AJ; Smith, T; Turski, L | 1 |
| Egashira, N; Fujiwara, M | 1 |
| Baker, D; Cabranes, A; de Lago, E; Fernández-Ruiz, J; López-Rodríguez, M; Ortega-Gutiérrez, S; Pryce, G; Ramos, JA | 1 |
| Bähr, M; Diem, R; Gerber, J; Kuhnert, AV; Maier, K; Merkler, D; Neusch, C; Taheri, N; Williams, SK | 1 |
| Bourbonnière, L; Didier-Bazes, M; Hardin-Pouzet, H; Krakowski, M; Owens, T; Tran, E | 1 |
| Pitt, D; Raine, CS; Werner, P | 2 |
| Alberdi, E; Domercq, M; Matute, C; Pérez-Cerdá, F; Pérez-Samartín, A; Sánchez-Gómez, MV | 1 |
| Hauben, E; Kipnis, J; Schori, H; Schwartz, M; Shaked, I; Yoles, E | 1 |
| Fisher, J; Haggiag, S; Levkovitch-Verbin, H; Mizrahi, T; Revel, M; Schori, H; Schwartz, M; Yoles, E | 1 |
| Hanada, T; Hashimoto, T; Nishizawa, Y; Ohgoh, M; Smith, T; Ueno, M; Watanabe, M; Yamanishi, Y | 1 |
5 review(s) available for glutamic acid and Allergic Encephalomyelitis
| Article | Year |
|---|---|
IL-1β dependent cerebellar synaptopathy in a mouse mode of multiple sclerosis.
Topics: Animals; Cerebellum; Encephalomyelitis, Autoimmune, Experimental; gamma-Aminobutyric Acid; Glutamic Acid; Interleukin-1beta; Mice; Multiple Sclerosis; Synapses; T-Lymphocytes | 2015 |
The link between inflammation, synaptic transmission and neurodegeneration in multiple sclerosis.
Topics: Animals; Cytokines; Demyelinating Diseases; Encephalomyelitis, Autoimmune, Experimental; Glutamic Acid; Inflammation; Multiple Sclerosis; Nerve Degeneration; Synaptic Transmission | 2010 |
Pathogenic implications of iron accumulation in multiple sclerosis.
Topics: Animals; Blood Vessels; Brain Chemistry; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Glutamic Acid; Humans; Iron; Iron, Dietary; Macrophages; Magnetic Resonance Imaging; Microglia; Multiple Sclerosis; Neurodegenerative Diseases; Neurotoxins | 2012 |
New perspectives in the studies on endocannabinoid and cannabis: abnormal behaviors associate with CB1 cannabinoid receptor and development of therapeutic application.
Topics: Animals; Behavior, Animal; Dronabinol; Encephalomyelitis, Autoimmune, Experimental; Glutamic Acid; Humans; Memory Disorders; Receptor, Cannabinoid, CB1 | 2004 |
The link between excitotoxic oligodendroglial death and demyelinating diseases.
Topics: Animals; Autoimmunity; Cell Death; Demyelinating Diseases; Encephalomyelitis, Autoimmune, Experimental; GluK2 Kainate Receptor; Glutamic Acid; Humans; Multiple Sclerosis; Neurotoxins; Oligodendroglia; Optic Nerve; Receptors, AMPA; Receptors, Kainic Acid | 2001 |
49 other study(ies) available for glutamic acid and Allergic Encephalomyelitis
| Article | Year |
|---|---|
Neuroprotective Effect of Glatiramer Acetate on Neurofilament Light Chain Leakage and Glutamate Excess in an Animal Model of Multiple Sclerosis.
Topics: Animals; Axons; Cerebrospinal Fluid; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Glatiramer Acetate; Glutamic Acid; Intermediate Filaments; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Myelin-Oligodendrocyte Glycoprotein; Neuroprotective Agents; Peptides | 2021 |
Myelin-associated glycoprotein activation triggers glutamate uptake by oligodendrocytes in vitro and contributes to ameliorate glutamate-mediated toxicity in vivo.
Topics: Amino Acid Transport Systems, Acidic; Animals; Antibodies, Monoclonal; Axons; Cells, Cultured; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Glutamic Acid; Glutathione; Mice; Mice, Inbred C57BL; Myelin-Associated Glycoprotein; Neurons; NF-E2-Related Factor 2; Oligodendroglia; Oxidative Stress; Protein Kinase C; Rats; Receptors, Glutamate; Signal Transduction | 2022 |
Cerebrospinal fluid, brain, and spinal cord levels of L-aspartate signal excitatory neurotransmission abnormalities in multiple sclerosis patients and experimental autoimmune encephalomyelitis mouse model.
Topics: Animals; Aspartic Acid; Brain; Cytokines; D-Aspartic Acid; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acids; Glutamic Acid; Mice; Multiple Sclerosis; Spinal Cord; Synaptic Transmission | 2023 |
Memantine Improves the Disturbed Glutamine and γ-Amino Butyric Acid Homeostasis in the Brain of Rats Subjected to Experimental Autoimmune Encephalomyelitis.
Topics: Amino Acids; Animals; Antifibrinolytic Agents; Brain; Encephalomyelitis, Autoimmune, Experimental; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Homeostasis; Memantine; Rats; Rats, Inbred Lew | 2023 |
Presynaptic Release-Regulating Sphingosine 1-Phosphate 1/3 Receptors in Cortical Glutamatergic Terminals: Adaptations in EAE Mice and Impact of Therapeutic FTY720.
Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Fingolimod Hydrochloride; Glutamic Acid; Mice; Sphingosine-1-Phosphate Receptors | 2023 |
MicroRNA-223 protects neurons from degeneration in experimental autoimmune encephalomyelitis.
Topics: Animals; Axons; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Glutamic Acid; Humans; Leukocytes, Mononuclear; Mice; MicroRNAs; Multiple Sclerosis; Nerve Degeneration; Neurodegenerative Diseases; Neurons; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Spinal Cord | 2019 |
Reduction of AMPA receptor activity on mature oligodendrocytes attenuates loss of myelinated axons in autoimmune neuroinflammation.
Topics: Animals; Axons; Calcium Signaling; Encephalomyelitis, Autoimmune, Experimental; Female; Glutamic Acid; Integrases; Male; Mice, Inbred C57BL; Myelin Sheath; Oligodendroglia; Protein Subunits; Receptors, AMPA | 2020 |
Prophylactic exposure to oral riluzole reduces the clinical severity and immune-related biomarkers of experimental autoimmune encephalomyelitis.
Topics: Administration, Oral; Animals; Biomarkers; Encephalomyelitis, Autoimmune, Experimental; Female; Glutamic Acid; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Pre-Exposure Prophylaxis; Riluzole; Severity of Illness Index | 2021 |
Laquinimod ameliorates excitotoxic damage by regulating glutamate re-uptake.
Topics: Animals; Anti-Inflammatory Agents; Cerebellum; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Female; Glutamic Acid; Infusions, Intraventricular; Mice; Mice, Inbred C57BL; Organ Culture Techniques; Quinolones; Random Allocation | 2018 |
Ndrg2 deficiency ameliorates neurodegeneration in experimental autoimmune encephalomyelitis.
Topics: Adaptor Proteins, Signal Transducing; Animals; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Proteins | 2018 |
Environmental training is beneficial to clinical symptoms and cortical presynaptic defects in mice suffering from experimental autoimmune encephalomyelitis.
Topics: Animals; Behavior, Animal; CD146 Antigen; Cerebral Cortex; Cyclic AMP; Cytokines; Encephalomyelitis, Autoimmune, Experimental; Environment; Exocytosis; Female; Glutamic Acid; Housing, Animal; Inflammation; Mice, Inbred C57BL; Presynaptic Terminals; Random Allocation; Spinal Cord; Synaptosomal-Associated Protein 25; Synaptosomes | 2019 |
Reduced Microglial Activity and Enhanced Glutamate Transmission in the Basolateral Amygdala in Early CNS Autoimmunity.
Topics: Animals; Basolateral Nuclear Complex; Complement System Proteins; Cytokines; Dendritic Spines; Encephalomyelitis, Autoimmune, Experimental; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Mice, Inbred C57BL; Microglia; Miniature Postsynaptic Potentials; Multiple Sclerosis; Neurons; Receptors, AMPA; Synaptic Transmission | 2018 |
Interleukin-1β alters glutamate transmission at purkinje cell synapses in a mouse model of multiple sclerosis.
Topics: Animals; Cerebellum; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Transporter 1; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Interleukin-1beta; Mice; Purkinje Cells; Synapses; Synaptic Transmission | 2013 |
CCL5-glutamate interaction in central nervous system: Early and acute presynaptic defects in EAE mice.
Topics: Age Factors; Animals; Animals, Newborn; Central Nervous System; Chemokine CCL5; Colforsin; D-Aspartic Acid; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Exocytosis; Female; Glutamic Acid; In Vitro Techniques; Mice; Mice, Inbred C57BL; Myelin-Oligodendrocyte Glycoprotein; Peptide Fragments; Potassium Chloride; Second Messenger Systems; Synaptosomes; Time Factors; Tritium | 2013 |
Cladribine interferes with IL-1β synaptic effects in experimental multiple sclerosis.
Topics: Animals; Cell Proliferation; Cerebral Cortex; Chelating Agents; Cladribine; Corpus Striatum; Disease Models, Animal; Drug Delivery Systems; Egtazic Acid; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glial Fibrillary Acidic Protein; Glutamic Acid; Immunosuppressive Agents; In Vitro Techniques; Interleukin-1beta; Mice; Mice, Inbred C57BL; Neuroglia; Patch-Clamp Techniques; Synapses | 2013 |
Glutamate excitotoxicity in the cerebellum mediated by IL-1β.
Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Female; Glutamic Acid; Interleukin-1beta; Purkinje Cells; Synapses; Synaptic Transmission | 2013 |
Matrine regulates glutamate-related excitotoxic factors in experimental autoimmune encephalomyelitis.
Topics: Alkaloids; Animals; Cerebral Cortex; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Female; gamma-Aminobutyric Acid; Glutamic Acid; Matrines; Quinolizines; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Spinal Cord | 2014 |
Pre- and postsynaptic type-1 cannabinoid receptors control the alterations of glutamate transmission in experimental autoimmune encephalomyelitis.
Topics: Animals; Corpus Striatum; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Excitatory Postsynaptic Potentials; Female; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Presynaptic Terminals; Receptor, Cannabinoid, CB1; Synaptic Transmission; Time Factors | 2014 |
Glutamate release machinery is altered in the frontal cortex of rats with experimental autoimmune encephalomyelitis.
Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Frontal Lobe; Glutamic Acid; Presynaptic Terminals; Rats, Wistar; Synapsins; Synaptosomes | 2015 |
Modulation of glutamate transport and receptor binding by glutamate receptor antagonists in EAE rat brain.
Topics: Animals; Brain; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Female; Glutamic Acid; Rats; Rats, Inbred Lew; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2014 |
Fumarates modulate microglia activation through a novel HCAR2 signaling pathway and rescue synaptic dysregulation in inflamed CNS.
Topics: AMP-Activated Protein Kinases; Animals; Brain; Cell Line; Dose-Response Relationship, Drug; Encephalomyelitis, Autoimmune, Experimental; Excitatory Postsynaptic Potentials; Female; Fumarates; Glutamic Acid; Mice, Inbred C57BL; Microglia; Neuroprotective Agents; NF-kappa B; Receptors, G-Protein-Coupled; Receptors, Nicotinic; Signal Transduction; Sirtuin 1; Synapses; Tissue Culture Techniques | 2015 |
GABAergic Agonists Modulate the Glutamate Release from Frontal Cortex Synaptosomes of Rats with Experimental Autoimmune Encephalomyelitis.
Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Frontal Lobe; GABA Agonists; Glutamic Acid; Phosphorylation; Presynaptic Terminals; Rats, Wistar; Synapsins; Synaptosomes | 2015 |
Blocking glutamate carboxypeptidase II inhibits glutamate excitotoxicity and regulates immune responses in experimental autoimmune encephalomyelitis.
Topics: Amino Acids; Animals; Astrocytes; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Female; Glutamate Carboxypeptidase II; Glutamic Acid; Humans; Immunohistochemistry; Mice; Mice, Inbred C57BL; Organophosphorus Compounds; Protease Inhibitors; Rats, Inbred Lew; Receptors, Metabotropic Glutamate; Spinal Cord; Th1 Cells; Xanthenes | 2016 |
Melanocortin-1 receptor activation is neuroprotective in mouse models of neuroinflammatory disease.
Topics: Action Potentials; alpha-MSH; Animals; Blood-Brain Barrier; Bone Marrow Cells; Cell Proliferation; Central Nervous System; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Flow Cytometry; Gene Expression Profiling; Glutamic Acid; Hippocampus; Magnetic Resonance Imaging; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Protein Binding; Receptor, Melanocortin, Type 1; T-Lymphocytes, Regulatory | 2016 |
Prophylactic versus Therapeutic Fingolimod: Restoration of Presynaptic Defects in Mice Suffering from Experimental Autoimmune Encephalomyelitis.
Topics: Administration, Oral; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Encephalomyelitis, Autoimmune, Experimental; Exocytosis; Female; Fingolimod Hydrochloride; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Immunosuppressive Agents; Mice; Mice, Inbred C57BL; Neuroglia; Organ Specificity; Spinal Cord; Synapses | 2017 |
Inhibition of Ca(2+)-dependent glutamate release from cerebral cortex synaptosomes of rats with experimental autoimmune encephalomyelitis.
Topics: Animals; Calcium; Calcium Channels; Calcium Signaling; Cattle; Cerebral Cortex; Cytosol; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Glutamic Acid; Neural Inhibition; Phosphorylation; Potassium Channel Blockers; Potassium Chloride; Presynaptic Terminals; Protein Synthesis Inhibitors; Rats; Rats, Inbred Strains; Synapsins; Synaptic Transmission | 2009 |
Blockade of glutamate release from microglia attenuates experimental autoimmune encephalomyelitis in mice.
Topics: Animals; Carbenoxolone; Cell Death; Diazooxonorleucine; Dose-Response Relationship, Drug; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Gap Junctions; Glutamic Acid; Glutaminase; Mice; Mice, Inbred C57BL; Microglia; Neurons; Spinal Cord | 2009 |
Exercise attenuates the clinical, synaptic and dendritic abnormalities of experimental autoimmune encephalomyelitis.
Topics: Animals; Antigens, CD; Corpus Striatum; Dendrites; Disease Models, Animal; Dronabinol; Encephalomyelitis, Autoimmune, Experimental; Female; Glutamic Acid; Glycoproteins; In Vitro Techniques; Mice; Mice, Inbred C57BL; Movement Disorders; Myelin-Oligodendrocyte Glycoprotein; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Peptide Fragments; Physical Conditioning, Animal; Silver Staining; Statistics, Nonparametric; Synapses; Synaptic Potentials | 2009 |
Alterations in glutamate transport and group I metabotropic glutamate receptors in the rat brain during acute phase of experimental autoimmune encephalomyelitis.
Topics: Animals; Astrocytes; Biological Transport; Blotting, Western; Brain; Cytokines; Encephalomyelitis, Autoimmune, Experimental; Female; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Neurons; Rats; Receptors, Metabotropic Glutamate; Synaptosomes; Time Factors | 2009 |
A diminished response to formalin stimulation reveals a role for the glutamate transporters in the altered pain sensitivity of mice with experimental autoimmune encephalomyelitis (EAE).
Topics: Amino Acid Sequence; Animals; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Formaldehyde; Glutamic Acid; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Pain; Pain Measurement; Pain Threshold; Phosphorylation; Receptors, Metabotropic Glutamate; Spinal Cord; Synaptic Transmission | 2010 |
Abnormal activity of the Na/Ca exchanger enhances glutamate transmission in experimental autoimmune encephalomyelitis.
Topics: Anesthetics, Local; Animals; Corpus Striatum; Electrophysiological Phenomena; Encephalomyelitis, Autoimmune, Experimental; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Kinetics; Membrane Potentials; Mice; Mice, Inbred C57BL; Myelin Proteins; Myelin-Associated Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; Neurons; Patch-Clamp Techniques; Psychomotor Performance; Receptors, Presynaptic; Sodium-Calcium Exchanger; Synaptic Transmission; Tetrodotoxin | 2010 |
Alterations of glutamate release in the spinal cord of mice with experimental autoimmune encephalomyelitis.
Topics: Animals; Aspartic Acid; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Glutamic Acid; Glycoproteins; In Vitro Techniques; Mice; Mice, Inbred C57BL; Myelin-Oligodendrocyte Glycoprotein; Neuroglia; Neurons; Peptide Fragments; Potassium Chloride; Spinal Cord; Subcellular Fractions; Tritium | 2010 |
Metabotropic glutamate receptor-4 modulates adaptive immunity and restrains neuroinflammation.
Topics: Adaptive Immunity; Animals; Cell Differentiation; Cytokines; Dendritic Cells; Encephalitis; Encephalomyelitis, Autoimmune, Experimental; Glutamic Acid; Mice; Mice, Knockout; Multiple Sclerosis; Nerve Degeneration; Neuroimmunomodulation; Receptors, Metabotropic Glutamate; Signal Transduction; T-Lymphocytes, Helper-Inducer | 2010 |
Cannabinoid CB1 receptors regulate neuronal TNF-α effects in experimental autoimmune encephalomyelitis.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amidohydrolases; Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Corpus Striatum; Dizocilpine Maleate; Dronabinol; Encephalomyelitis, Autoimmune, Experimental; Endocannabinoids; Etanercept; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Immunoglobulin G; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Neurons; Polyunsaturated Alkamides; Receptor, Cannabinoid, CB1; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha | 2011 |
Oxidative stress and reduced glutamine synthetase activity in the absence of inflammation in the cortex of mice with experimental allergic encephalomyelitis.
Topics: Analysis of Variance; Animals; Calcium; Cerebral Cortex; Chromatography, High Pressure Liquid; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Encephalitis; Encephalomyelitis, Autoimmune, Experimental; Female; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Glutathione; Glutathione Disulfide; Guinea Pigs; Mice; Myelin Basic Protein; NAD; NADP; Nitric Oxide Synthase Type II; Oxidative Stress; Tandem Mass Spectrometry | 2011 |
Participation of the GABAergic system on the glutamate release of frontal cortex synaptosomes from Wistar rats with experimental autoimmune encephalomyelitis.
Topics: 4-Aminopyridine; Animals; Calcium; Encephalomyelitis, Autoimmune, Experimental; Flunitrazepam; Frontal Lobe; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Glutamic Acid; Nerve Endings; Phosphorylation; Rats; Rats, Wistar; Receptors, GABA-A; Synapsins; Synaptosomes | 2011 |
Increased expression of cystine/glutamate antiporter in multiple sclerosis.
Topics: Adult; Aged; Aged, 80 and over; Amino Acid Transport System y+; Amino Acid Transport Systems, Acidic; Animals; Cell Line; Cystine; Encephalomyelitis, Autoimmune, Experimental; Female; Glutamic Acid; Glutathione; Homeostasis; Humans; Inflammation; Male; Middle Aged; Multiple Sclerosis; Optic Nerve; Rats; Rats, Inbred Lew; Spinal Cord; Young Adult | 2011 |
Oral fingolimod rescues the functional deficits of synapses in experimental autoimmune encephalomyelitis.
Topics: Animals; Dendritic Spines; Encephalomyelitis, Autoimmune, Experimental; Excitatory Postsynaptic Potentials; Female; Fingolimod Hydrochloride; Glutamic Acid; Glycoproteins; Immunosuppressive Agents; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Myelin-Oligodendrocyte Glycoprotein; Peptide Fragments; Propylene Glycols; Sphingosine; Synapses; Synaptic Transmission | 2012 |
4-iodophenyl isothiocyanate: a neuroprotective compound.
Topics: 1-Methyl-4-phenylpyridinium; Analysis of Variance; Animals; Cells, Cultured; Cerebral Cortex; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Embryo, Mammalian; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glucose; Glutamic Acid; Herbicides; Hypoxia; Iodobenzenes; Isothiocyanates; L-Lactate Dehydrogenase; Monoamine Oxidase; N-Methylaspartate; Neurites; Neuroglia; Neurons; Neuroprotective Agents; Peroxides; Protein Binding; Rats; Rats, Wistar | 2012 |
Abnormal NMDA receptor function exacerbates experimental autoimmune encephalomyelitis.
Topics: Animals; Dizocilpine Maleate; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Receptors, N-Methyl-D-Aspartate; Synapses; Voltage-Gated Sodium Channels | 2013 |
Multiple sclerosis and glutamate.
Topics: Animals; Brain Stem; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Mice; Mice, Inbred Strains; Multiple Sclerosis; Nootropic Agents; Pyrrolidinones; Quinoxalines; Rats; Receptors, AMPA; Spinal Cord | 2003 |
UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Arachidonic Acids; Brain Chemistry; Disease Models, Animal; Disease Progression; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Encephalomyelitis, Autoimmune, Experimental; Endocannabinoids; Exploratory Behavior; Furans; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Huntington Disease; Male; Malonates; Movement Disorders; Multiple Sclerosis; Nitro Compounds; Oxidopamine; Polyunsaturated Alkamides; Propionates; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine 3-Monooxygenase | 2006 |
Multiple neuroprotective mechanisms of minocycline in autoimmune CNS inflammation.
Topics: Acute Disease; Animals; Anti-Bacterial Agents; Apoptosis; Cell Survival; Encephalomyelitis, Autoimmune, Experimental; Evoked Potentials, Visual; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Female; Glutamic Acid; Minocycline; Myelin Proteins; Myelin-Associated Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; Neuroprotective Agents; Optic Nerve; Optic Neuritis; Rats; Rats, Inbred BN; Retinal Ganglion Cells; Severity of Illness Index | 2007 |
Glutamate metabolism is down-regulated in astrocytes during experimental allergic encephalomyelitis.
Topics: Adoptive Transfer; Animals; Astrocytes; Brain; Encephalomyelitis, Autoimmune, Experimental; Female; Glial Fibrillary Acidic Protein; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamic Acid; Mice; Mice, Inbred Strains; Myelin Basic Protein; Paralysis; Polymerase Chain Reaction; RNA, Messenger; Spinal Cord; T-Lymphocytes; Transcription, Genetic | 1997 |
Glutamate excitotoxicity in a model of multiple sclerosis.
Topics: Animals; Axons; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Lymph Nodes; Lymphocyte Activation; Mice; Mice, Inbred Strains; Multiple Sclerosis; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; T-Lymphocytes | 2000 |
Glutamate excitotoxicity--a mechanism for axonal damage and oligodendrocyte death in Multiple Sclerosis?
Topics: Animals; Axons; Cell Death; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glutaminase; Humans; Mice; Mice, Inbred Strains; Multiple Sclerosis; Myelitis; Neuroprotective Agents; Neurotoxins; Oligodendroglia; Quinoxalines; Receptors, AMPA | 2000 |
Neuronal survival after CNS insult is determined by a genetically encoded autoimmune response.
Topics: Animals; Autoimmunity; Cell Count; Cell Survival; Central Nervous System; Disease Models, Animal; Drug Administration Routes; Encephalomyelitis, Autoimmune, Experimental; Female; Genetic Predisposition to Disease; Glutamic Acid; Immunity, Cellular; Injections; Male; Mice; Mice, Inbred Strains; Mice, Nude; Nerve Crush; Neurons; Optic Nerve Injuries; Rats; Rats, Inbred F344; Rats, Inbred Lew; Rats, Sprague-Dawley; Retinal Ganglion Cells; Species Specificity; Spinal Cord Injuries; T-Lymphocytes; Wounds, Nonpenetrating | 2001 |
Increased post-traumatic survival of neurons in IL-6-knockout mice on a background of EAE susceptibility.
Topics: Animals; Cell Survival; Drug Resistance; Encephalomyelitis, Autoimmune, Experimental; Female; Genetic Predisposition to Disease; Glutamic Acid; Interleukin-6; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Crush; Nerve Degeneration; Neurons; Optic Nerve Injuries; Retinal Ganglion Cells | 2001 |
Altered expression of glutamate transporters in experimental autoimmune encephalomyelitis.
Topics: Amino Acid Transport System X-AG; Animals; Carrier Proteins; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Gene Expression; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Quinoxalines; Rats; Rats, Inbred Lew; Receptors, AMPA; RNA, Messenger; Spinal Cord; Symporters; Tritium | 2002 |