glutamic acid has been researched along with Alcoholism in 148 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (2.70) | 18.7374 |
| 1990's | 19 (12.84) | 18.2507 |
| 2000's | 44 (29.73) | 29.6817 |
| 2010's | 56 (37.84) | 24.3611 |
| 2020's | 25 (16.89) | 2.80 |
| Authors | Studies |
|---|---|
| de la Torre, R; Flores-López, M; Gavito, AL; Pastor, A; Pavón, FJ; Rodríguez de Fonseca, F; Sánchez-Marín, L; Serrano, A; Suárez, J | 1 |
| Bokhan, NA; Davydova, TV; Galkin, SA; Nevidimova, TI; Savochkina, DN; Vetrile, LA; Zakharova, IA | 1 |
| Angarita, GA; Carson, RE; Cosgrove, KP; Esterlis, I; Hillmer, AT; Krystal, JH; O'Malley, SS; Scheinost, D; Smart, K; Worhunsky, PD | 1 |
| Browning, BD; Green, R; Kirkland, AE; Leggio, L; Meyerhoff, DJ; Squeglia, LM | 1 |
| Alasmari, F; Althobaiti, YS; Das, SC; Hammad, AM; Sari, Y | 1 |
| Besheer, J; Joffe, ME; Tyler, RE | 1 |
| Becker, HC; Griffin, WC; Lopez, MF; Woodward, JJ | 1 |
| Brady, KT; Browning, BD; Ferguson, PL; Gray, KM; Green, R; Kirkland, AE; Liu, H; Maralit, AM; Meyerhoff, DJ; Miranda, R; Prisciandaro, JJ; Squeglia, LM; Tomko, RL | 1 |
| Cai, W; Dong, F; Guo, Q; Hou, W; Hu, Y; Huang, R; Sui, F; Wang, H; Xue, T; Yu, D; Yuan, K; Zhou, M | 1 |
| DeMiceli, KG; Faccidomo, SP; Hodge, CW; Hoffman, JL; May, AM; Smith, EN; Taylor, SM; Whindleton, CM | 1 |
| Egerton, A | 1 |
| McCool, BA; McGinnis, MM | 1 |
| Kakanakova, A; Maes, M; Popov, S | 1 |
| McCool, BA; McGinnis, MM; Parrish, BC | 1 |
| Alen, F; Arco, R; Ballesta, A; Decara, J; Gómez de Heras, R; Orio, L; Pavón, FJ; Ramírez-López, M; Rodríguez de Fonseca, F; Serrano, A; Suárez, J; Vadas, E; Vargas, A | 1 |
| Hays, LR; Lile, JA; Rayapati, AO; Rush, CR; Stoops, WW; Strickland, JC | 1 |
| Chang, L; Cunningham, SI; Ernst, T; Shokri-Kojori, E; Tomasi, DG; Volkow, ND; Wang, GJ; Wiers, CE | 1 |
| Gioia, DA; Homanics, GE; Lopez, M; Woodward, JJ; Zamudio, PA | 1 |
| Gupta, A; Kaur, A; Khan, H; Singh, TG | 1 |
| Arends, MA; Elvig, SK; Koob, GF; McGinn, MA; Smith, C; Vendruscolo, LF | 1 |
| Boehm, SL; Logrip, ML; Rangel-Barajas, C | 1 |
| Ferrera, VP; Foltin, RW; Grassetti, A; Martinez, D; Salling, MC | 1 |
| Anton, RF; Book, S; Bristol, E; Brown, TR; Hoffman, M; Prisciandaro, JJ; Voronin, K | 1 |
| Gakare, SG; Patni, PP; Ugale, RR; Varghese, SS; Wagh, SA | 1 |
| Fedotcheva, NI; Kovalyov, LI; Kruglov, AG; Lemasters, JJ; Nikiforova, AB; Teplova, VV | 1 |
| Bekker, A; Fu, R; Kang, S; Li, J; Shah, A; Ye, JH; Zhang, H; Zuo, W | 1 |
| Correia, D; Khom, S; Kirson, D; Luu, G; Oleata, CS; Roberto, M; Schweitzer, P; Varodayan, FP | 1 |
| Cheng, H; Dharmadhikari, S; Dydak, U; Finn, P; Kellar, D; Lake, A; Newman, S; Rebec, GV | 1 |
| Buczynski, MW; Cravatt, BF; Martin-Fardon, R; Natividad, LA; Parsons, LH; Pavon, FJ; Polis, IY; Roberto, M; Rodriguez de Fonseca, F; Schlosburg, J; Serrano, A; Stouffer, DG; Zorrilla, EP | 1 |
| Degenhardt, F; Ende, G; Foo, JC; Frank, J; Frischknecht, U; Hall, ASM; Heilmann-Heimbach, S; Hermann, D; Kiefer, F; Mann, K; Nöthen, MM; Rietschel, M; Sack, M; Sommer, WH; Spanagel, R; Streit, F; Treutlein, J; Witt, SH | 1 |
| Alasmari, F; Goodwani, S; McCullumsmith, RE; Sari, Y | 1 |
| Bifone, A; Cannella, N; Ciccocioppo, R; Cippitelli, A; Domi, E; Gozzi, A; Li, H; Matzeu, A; Scuppa, G; Ubaldi, M; Weiss, F | 1 |
| Anton, RF; Brown, TR; Prescot, AP; Prisciandaro, JJ; Renshaw, PF; Schacht, JP | 2 |
| Cuzon Carlson, VC; Grant, KA; Herman, MA; Jimenez, VA; Roberto, M; Walter, NA | 1 |
| Anton, RF; Brenner, HM; Brown, TR; Prescot, AP; Prisciandaro, JJ; Renshaw, PF; Schacht, JP | 1 |
| Alén, F; Arco, R; Bajo, M; Ballesta, A; Khom, S; Kirson, D; Martin-Fardon, R; Natividad, LA; Patel, RR; Roberto, M; Rodríguez de Fonseca, F; Rubio, L; Suárez, J; Varodayan, FP | 1 |
| Arolt, V; Bauer, J; Bening, J; Heindel, W; Kugel, H; Ohrmann, P; Patschke, J; Pedersen, A; Scherbaum, N | 1 |
| De Feyter, HM; Guidone, E; Gulanski, BI; Harman, S; Jiang, L; Koretski, J; Krystal, JH; Mason, GF; Petrakis, IL; Pittman, B; Weinzimer, SA | 1 |
| Demirakca, T; Ende, G; Frischknecht, U; Hermann, D; Hoerst, M; Mann, K; Rabinstein, J; Tunc-Skarka, N; Vollstädt-Klein, S; Weber-Fahr, W; Wichert, S | 1 |
| Holmes, A; Krystal, JH; Spanagel, R | 1 |
| Becker, HC; Griffin, WC; Haun, HL; Hazelbaker, CL; Ramachandra, VS | 1 |
| Rao, PS; Sari, Y | 1 |
| Qi, Z; Tretter, F; Voit, EO | 1 |
| Alhaddad, H; Das, SC; Sari, Y | 1 |
| Biggio, G; Cannizzaro, C; Diana, M; Fois, GR; Licheri, V; Masala, N; Muggironi, G; Mulas, G; Sanna, E; Spiga, S; Talani, G | 1 |
| Becker, HC; Mulholland, PJ | 1 |
| Abé, C; Batki, SL; Meyerhoff, DJ; Pennington, DL | 1 |
| Cui, SQ; Dong, PX; Fu, CH; Gu, XL; Sun, HW; Wang, Q; Wang, XM; Xiao, B; Zhang, YC; Zheng, Y | 1 |
| Balcar, VJ; Kashem, MA; Pow, DV; Šerý, O; Sultana, N | 1 |
| Das, SC; Hristov, AM; Sari, Y; Yamamoto, BK | 1 |
| Cohen-Gilbert, JE; Crowley, DJ; Jensen, JE; Rosso, IM; Silveri, MM; Sneider, JT | 1 |
| Deehan, GA; Hauser, SR; Knight, CP; McBride, WJ; Rodd, ZA; Toalston, JE; Truitt, WA; Waeiss, RA | 1 |
| Burnett, EJ; Chandler, LJ; Trantham-Davidson, H | 1 |
| Cosgrove, KP; Fucito, LM; Hillmer, AT; Mason, GF; O'Malley, SS | 1 |
| Dalvie, S; Fabbri, C; Ramesar, R; Serretti, A; Stein, DJ | 1 |
| Lipiński, M; Matuszek, Ż; Mijakowska, Z; Radwanska, K; Trąbczyńska, A; Ziółkowska, M; Łęski, S; Łukasiewicz, K | 1 |
| Carr, RA; Colrain, IM; Mayer, D; Pfefferbaum, A; Rohlfing, T; Sullivan, EV; Zahr, NM | 1 |
| Cicin-Šain, L; Kovak-Mufić, A; Marušić, S; Matošić, A; Vidrih, B | 1 |
| Biernacka, JM; Choi, DS; Feeder, SE; Frye, MA; Gunderson, LJ; Hinton, DJ; Karpyak, VM; Port, JD | 1 |
| Balcar, VJ; Kashem, MA; Lee, A; Pow, DV; Šerý, O | 1 |
| Demirakca, T; Dieter, S; Ende, G; Falfan-Melgoza, C; Frischknecht, U; Hermann, D; Kiefer, F; Krumm, B; Mann, KF; Sack, M; Sommer, WH; Spanagel, R; Tunc-Skarka, N; van Eijk, J; Wang, GY; Weber-Fahr, W | 1 |
| Roberto, M; Varodayan, FP | 1 |
| Krishnan-Sarin, S; Krystal, JH; O'Malley, S; Pearlson, G; Petrakis, IL; Yoon, G | 1 |
| Alasmari, F; Goodwani, S; Sari, Y; Saternos, H | 1 |
| Klugmann, M; Szumlinski, KK | 1 |
| Bakalkin, G; Garrick, T; Harper, C; Henriksson, R; Kuzmin, A; Okvist, A; Sheedy, D; Yakovleva, T | 1 |
| Carroll, FI | 1 |
| Boix, J; Felipo, V; Guerri, C; Pascual, M | 1 |
| Biermann, T; Bleich, S; Frieling, H; Hillemacher, T; Kornhuber, J; Lenz, B; Muschler, M; Reulbach, U | 1 |
| Ehringer, MA; Hoft, NR; Schlaepfer, IR | 1 |
| Allen, R; Ballini, C; Colivicchi, MA; Corte, LD; de Witte, P; Dexter, D; Lallemand, F; Schol, F; Ward, RJ | 1 |
| Grueter, BA; Kash, TL; Klug, JR; McElligott, ZA; Nobis, WP; Patel, S; Winder, DG | 1 |
| Licata, SC; Renshaw, PF | 1 |
| Christian, DT; Diaz, MR; Läck, AK; McCool, BA | 1 |
| Adams, LJ; Doty, L; George, DT; Heilig, M; Hommer, D; Lifshitz, M; Momenan, R; Schwandt, ML; Shen, J; Singley, E; Spanagel, R; Umhau, JC; Vengeliene, V; Zhang, Y | 1 |
| Bartsch, D; Brors, B; Dahmen, N; Deussing, J; Eils, R; Ende, G; Gallinat, J; Gebicke-Haerter, P; Heinz, A; Jäger, W; Kiefer, F; Mann, K; Matthäus, F; Nöthen, M; Rietschel, M; Sartorius, A; Schütz, G; Sommer, WH; Spanagel, R; Sprengel, R; Walter, H; Wichmann, E; Wienker, T; Wurst, W; Zimmer, A | 1 |
| Cleva, RM; Gass, JT; Olive, MF; Sinclair, CM; Widholm, JJ | 1 |
| Bogenschutz, M; Caprihan, A; Gasparovic, C; Kalyanam, R; Lysne, P; Monnig, M; Mullins, P; Ruhl, D; Thoma, R; Tonigan, S; Yeo, RA | 1 |
| Kalsi, G; Kendler, KS; Kertes, DA; Reimers, MA; Riley, BP | 1 |
| Anton, RF; Baros, AM; Latham, PK; Myrick, H; Randall, PK; Schacht, JP; Waid, LR; Wright, TM | 1 |
| Ende, G; Frischknecht, U; Hansson, AC; Hermann, D; Hoerst, M; Kiefer, F; Krumm, B; Mann, K; Perreau-Lenz, S; Sartorius, A; Sommer, WH; Spanagel, R; Tunc-Skarka, N; Weber-Fahr, W | 1 |
| Alexander, GM; Bennett, AJ; Burnett, EJ; Daunais, JB; Friedman, DP; Godwin, DW; Graef, JD; Hammarback, JA; Nordskog, BK; Suomi, SJ | 1 |
| Choi, DS; Haydon, PG; Hinton, DJ; McIver, SR; Nam, HW; Parkinson, FE; Sari, Y; Thakkar, MM | 1 |
| Brunt, TM; McMaster, MT; Niesink, RJ; van Amsterdam, JG | 1 |
| Durazzo, TC; Meyerhoff, DJ; Mon, A | 1 |
| Gilpin, NW; Roberto, M; Siggins, GR | 1 |
| Braff, DL; Kelsoe, JR; Schuckit, MA; Wilhelmsen, KC | 1 |
| Spanagel, R | 1 |
| Bleich, S; Kornhuber, J; Maler, JM; Sperling, W; Wiltfang, J | 1 |
| Preuss, U; Soyka, M | 1 |
| DE MAIO, D | 1 |
| DRAGO, E; POSTIGLIONE, G; RIGAMONTI, L; RIGAMONTI, PP | 1 |
| Goldman, D; Heinz, A; Higley, JD; Krystal, JH; Schäfer, M | 1 |
| Brower, KJ | 1 |
| De Witte, P | 1 |
| Joyner, PW; McMillen, BA; Parmar, CA; Tyer, WE; Williams, HL | 1 |
| Besheer, J; Hodge, CW | 1 |
| Abarca, C; Albrecht, U; Depner, M; Holzberg, D; Lascorz, J; Lathrop, M; Magnone, MC; Matsuda, F; Pendyala, G; Sanchis-Segura, C; Schreiber, S; Schumann, G; Soyka, M; Spanagel, R; Zghoul, T | 1 |
| Bart, G; Kreek, MJ; Yuferov, V | 1 |
| Littleton, J | 1 |
| Cowen, MS; Djouma, E; Lawrence, AJ | 1 |
| Johnson, BA | 1 |
| Fourgeaud, L | 1 |
| Buonopane, A; Petrakis, IL | 1 |
| Bochenski, M; Danysz, W; Kotlinska, J | 1 |
| Galindo, R; Hendricson, AH; Lovinger, D; Mameli, M; Morrisett, R; Pietrzykowski, AZ; Roberto, M; Siggins, GR; Treistman, SN; Valenzuela, F; Weiner, J; Zhang, TA; Zhu, PJ | 1 |
| Roberto, M; Ron, D; Winder, D; Woodward, JJ | 1 |
| Bell, R; Carpenter-Hyland, E; Chandler, LJ; Hendricson, AW; Maldve, RE; Morrisett, RA; Sari, Y; Szumlinski, KK; Zhou, FC | 1 |
| Añez, Y; Coutin-Churchman, P; Moreno, R; Vergara, F | 1 |
| Hannun, RA; Kapasova, Z; Lominac, KD; Middaugh, LD; Patterson, C; Szumlinski, KK | 1 |
| Benjamini, Y; Elmer, GI; Frank, BC; Kafkafi, N; Lee, NH; Letwin, NE; Luu, T; Mayo, C | 1 |
| Chandler, LJ; Lapish, CC; Seamans, JK | 1 |
| Anthony, B; Deng, P; Dunn, KW; Lindquist, WB; Xu, ZC; Zhou, FC | 1 |
| Bowers, MS; Diab, ME; Friedman, R; Henze, LM; Lominac, KD; Szumlinski, KK | 1 |
| Quertemont, E; Tambour, S | 1 |
| Köhnke, MD | 1 |
| Gass, JT; Olive, MF | 1 |
| An, SK; Jang, DP; Kim, IY; Kim, JJ; Kim, SI; Lee, E; Namkoong, K; Park, S; Yoon, KJ | 1 |
| Flatscher-Bader, T; Landis, N; Wilce, PA; Zuvela, N | 1 |
| Bilbao, A; Molander, A; Spanagel, R; Vengeliene, V | 1 |
| Behr, J; Breiter, HC; Heinz, A; Kitzrow, W; Makris, N; Mohr, J; Obermayer, K; Priller, J; Puls, I; Wrase, J | 1 |
| Cummins, JT; Keller, E; von Hungen, K | 1 |
| Hoffman, PL; Iorio, KR; Snell, LD; Tabakoff, B | 1 |
| Harris, RA; Sanna, E | 1 |
| Aliguliyev, AR; Aliyev, NA; Aliyev, ZN | 1 |
| Diana, M; Gessa, G; Rossetti, ZL | 1 |
| Anderson, KJ; Hunter, BE; Tremwel, MF | 1 |
| Browning, MD; Hoffman, PL; Lickteig, RL; Nunley, KR; Snell, LD; Tabakoff, B | 1 |
| Dlugosz, JW; Gabryelewicz, A; Pawlicka, E; Poplawski, C; Wroblewski, E | 1 |
| Bungay, PM; Gonzales, R; Kilanmaa, K; Rosselti, ZL; Samson, HH | 1 |
| Dahchour, A; De Witte, P; Quertemont, E | 1 |
| Baird, TJ; Beatty, WW; Briscoe, RJ; Floyd, RA; Gauvin, DV; Tabatabaie, T; Vallett, M | 1 |
| Coyle, JT; Tsai, G | 1 |
| Cai, Z; Rhodes, PG | 1 |
| Wickelgren, I | 1 |
| Bolo, N; Dahchour, A; De Witte, P; Durbin, P; Macher, JP; Muzet, M; Nédélec, JF | 1 |
| Mochizuki, Y; Oishi, M; Sanuki, E | 1 |
| Anderson, KJ; Freund, G | 1 |
| Dahchour, A; De Witte, P | 1 |
| Ostapowicz, A; Samochowiec, J; Sander, T; Schmidt, LG; Smolka, M; Winterer, G | 1 |
| Devaud, LL | 1 |
| Ball, D; De Witte, P; Marshall, EJ; Martinez, J; Ward, RJ | 1 |
| Favalli, L; Frattini, P; Govoni, S; Masoero, E; Pascale, A; Rozza, A; Scelsi, R | 1 |
| Eriksson, CJ; Härkönen, M; Orpana, AK | 1 |
| Foye, J; Freed, WJ; Galton, N; Kleinman, JE; Michaelis, EK; Michaelis, ML; Phillips, I | 1 |
41 review(s) available for glutamic acid and Alcoholism
| Article | Year |
|---|---|
Brain metabolite alterations related to alcohol use: a meta-analysis of proton magnetic resonance spectroscopy studies.
Topics: Alcoholism; Aspartic Acid; Brain; Choline; Glutamic Acid; Humans; Proton Magnetic Resonance Spectroscopy | 2022 |
Advances in translating mGlu
Topics: Alcoholism; Animals; Glutamic Acid; Humans; Mice; Mice, Knockout; Mood Disorders; Synaptic Transmission | 2022 |
The potential of
Topics: Acamprosate; Alcoholism; Brain; Central Nervous System Agents; Drug Development; Glutamic Acid; Humans; Ketamine; Neuroimaging; Proton Magnetic Resonance Spectroscopy; Reproducibility of Results | 2021 |
Adolescent Vulnerability to Alcohol Use Disorder: Neurophysiological Mechanisms from Preclinical Studies.
Topics: Adolescent; Alcoholism; Brain; GABAergic Neurons; Glutamic Acid; Humans; Synapses; Synaptic Transmission | 2020 |
Immunological Disturbances and Neuroimaging Findings in Major Depressive Disorder (MDD) and Alcohol Use Disorder (AUD) Comorbid Patients.
Topics: Alcoholism; Anxiety Disorders; Brain; Comorbidity; Cytokines; Depressive Disorder, Major; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Inositol; Magnetic Resonance Imaging; Neuroimaging; Neuropsychological Tests; Neurotransmitter Agents; Severity of Illness Index | 2020 |
Novel Targets Explored in the Treatment of Alcohol Withdrawal Syndrome.
Topics: Alcoholism; Animals; Brain; Ethanol; Glutamic Acid; Humans; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome | 2021 |
Tolerance to alcohol: A critical yet understudied factor in alcohol addiction.
Topics: Alcohol Drinking; Alcoholism; Animals; Behavior, Addictive; Brain; Disease Models, Animal; Dopamine; Drug Tolerance; Ethanol; Female; Glutamic Acid; Humans; Male; Mice; Neurobiology; Norepinephrine; Rats; Serotonin; Sex Characteristics | 2021 |
The lateral habenula and alcohol: Role of glutamate and M-type potassium channels.
Topics: Alcohol Drinking; Alcoholism; Animals; Ethanol; Glutamic Acid; Habenula; Humans; Nerve Net; Potassium Channels | 2017 |
Role of glutamatergic system and mesocorticolimbic circuits in alcohol dependence.
Topics: Alcoholism; Animals; Glutamic Acid; Humans; Limbic System; Nerve Net; Prefrontal Cortex; Signal Detection, Psychological; Up-Regulation | 2018 |
Glutamatergic targets for new alcohol medications.
Topics: Alcoholism; Animals; Drug-Seeking Behavior; Glutamic Acid; Humans; Molecular Targeted Therapy; Protein Subunits; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome | 2013 |
Neurochemical mechanisms of alcohol withdrawal.
Topics: Alcoholism; Animals; Biogenic Amines; Brain; Brain Chemistry; Glutamic Acid; Humans; Neurotransmitter Agents; Substance Withdrawal Syndrome | 2014 |
GLAST But Not Least--Distribution, Function, Genetics and Epigenetics of L-Glutamate Transport in Brain--Focus on GLAST/EAAT1.
Topics: Alcoholism; Animals; Biological Transport, Active; Brain Chemistry; Epigenesis, Genetic; Excitatory Amino Acid Transporter 1; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans | 2015 |
Glutamatergic plasticity and alcohol dependence-induced alterations in reward, affect and cognition.
Topics: Affect; Alcoholism; Animals; Brain; Cognition; Glutamic Acid; Humans; Neuronal Plasticity; Reward | 2016 |
How Imaging Glutamate, γ-Aminobutyric Acid, and Dopamine Can Inform the Clinical Treatment of Alcohol Dependence and Withdrawal.
Topics: Alcoholism; Cross-Sectional Studies; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Neuroimaging; Substance Withdrawal Syndrome; Treatment Outcome | 2015 |
NEUROBIOLOGICAL BASES OF ALCOHOL ADDICTION.
Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Brain; Disulfiram; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Minisatellite Repeats; Monoamine Oxidase; Naltrexone; Narcotic Antagonists; Neuropeptide Y; Norepinephrine; Ondansetron; Polymorphism, Genetic; Serotonin; Synaptic Transmission; Taurine | 2016 |
Synaptic targets: Chronic alcohol actions.
Topics: Alcoholism; Animals; Brain; Ethanol; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Neurons; Synapses; Synaptic Transmission | 2017 |
Metabotropic and ionotropic glutamate receptors as potential targets for the treatment of alcohol use disorder.
Topics: Alcoholism; Alcohols; Animals; Glutamic Acid; Receptors, Ionotropic Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2017 |
Targeting Homer genes using adeno-associated viral vector: lessons learned from behavioural and neurochemical studies.
Topics: Adenoviridae; Alcoholism; Animals; Arousal; Behavior, Animal; Brain; Carrier Proteins; Emotions; Gene Transfer Techniques; Genes, Immediate-Early; Genetic Vectors; Glutamic Acid; Homer Scaffolding Proteins; Mice; Mice, Knockout; Mice, Transgenic; Mutagenesis, Site-Directed; Substance-Related Disorders; Synaptic Transmission | 2008 |
Antagonists at metabotropic glutamate receptor subtype 5: structure activity relationships and therapeutic potential for addiction.
Topics: Alcoholism; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; CHO Cells; Cricetinae; Cricetulus; Depressive Disorder; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Mice; Mice, Knockout; Protein Conformation; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Smoking; Structure-Activity Relationship; Substance-Related Disorders | 2008 |
The genetic components of alcohol and nicotine co-addiction: from genes to behavior.
Topics: Age of Onset; Alcoholism; Animals; Comorbidity; Dopamine; gamma-Aminobutyric Acid; Genetic Linkage; Glutamic Acid; Humans; Mice; Motivation; Receptors, Nicotinic; Risk Factors; Serotonin; Smoking; Tobacco Use Disorder | 2008 |
Neurochemistry of drug action: insights from proton magnetic resonance spectroscopic imaging and their relevance to addiction.
Topics: Alcoholism; Animals; Appetite Stimulants; Aspartic Acid; Brain; Choline; Cocaine; Creatine; Glutamic Acid; Humans; Inositol; Magnetic Resonance Spectroscopy; Marijuana Abuse; Neurochemistry; Opiate Alkaloids; Smoking; Substance-Related Disorders; Toluene | 2010 |
Glutamate plasticity in the drunken amygdala: the making of an anxious synapse.
Topics: Alcoholism; Amygdala; Animals; Ethanol; Glutamic Acid; Humans; Neuronal Plasticity; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 2010 |
An integrated genome research network for studying the genetics of alcohol addiction.
Topics: Alcoholism; Animals; Brain; Cause of Death; Cooperative Behavior; Cross-Sectional Studies; Genetic Predisposition to Disease; Genetic Research; Genome-Wide Association Study; Genotype; Glutamic Acid; Humans; Interdisciplinary Communication; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Rats; Recurrence; Risk; Survival Analysis | 2010 |
Adenosine and glutamate signaling in neuron-glial interactions: implications in alcoholism and sleep disorders.
Topics: Adenosine; Alcoholism; Animals; Cell Communication; Excitatory Amino Acid Transporter 2; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Neuroglia; Neurons; Signal Transduction; Sleep Wake Disorders; SNARE Proteins | 2012 |
Possible long-term effects of γ-hydroxybutyric acid (GHB) due to neurotoxicity and overdose.
Topics: Alcoholism; Anesthetics; Anesthetics, Dissociative; Animals; Central Nervous System Depressants; Cognition Disorders; Coma; Drug Overdose; Ethanol; Glutamic Acid; Humans; Illicit Drugs; Ketamine; Neurotoxicity Syndromes; Oxidative Stress; Sodium Oxybate; Substance Withdrawal Syndrome; Substance-Related Disorders; Succinate-Semialdehyde Dehydrogenase | 2012 |
The central amygdala and alcohol: role of γ-aminobutyric acid, glutamate, and neuropeptides.
Topics: Alcoholism; Amygdala; Central Nervous System Depressants; Corticotropin-Releasing Hormone; Ethanol; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Neuropeptide Y; Neuropeptides; Nociceptin; Opioid Peptides; Synaptic Transmission | 2012 |
[The role of the glutamatergic system in alcohol addiction].
Topics: Alcoholism; Animals; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate; Secondary Prevention | 2003 |
[Excitatory neurotransmission in alcoholism].
Topics: Alcoholism; Animals; Excitatory Amino Acids; Glutamic Acid; Homocysteine; Humans; Neurotransmitter Agents; Prognosis; Receptors, Glutamate; Synaptic Transmission | 2003 |
[Glutamatergic mechanisms in alcohol dependence--genetic, molecular-biological and neuropharmacological findings].
Topics: Alcoholism; Animals; Central Nervous System Depressants; Ethanol; Glutamic Acid; Humans; Receptors, Glutamate | 2003 |
Neurobiological correlates of the disposition and maintenance of alcoholism.
Topics: Acute Disease; Alcoholism; Brain; Chronic Disease; Dopamine; Drug Tolerance; Ethanol; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glutamic Acid; Recurrence; Reward; Risk Factors; Serotonin; Substance Withdrawal Syndrome; Synaptic Transmission | 2003 |
Insomnia, alcoholism and relapse.
Topics: Acetylcholine; Adenosine; Alcoholism; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Norepinephrine; Polysomnography; Recurrence; Sleep Initiation and Maintenance Disorders; Sleep, REM | 2003 |
Neurochemical mechanisms underlying alcohol withdrawal.
Topics: Alcoholism; Animals; Calcium Channels; Ethanol; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Substance Withdrawal Syndrome | 1998 |
Recent advances in the development of treatments for alcohol and cocaine dependence: focus on topiramate and other modulators of GABA or glutamate function.
Topics: Alcoholism; Animals; Cocaine-Related Disorders; Fructose; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Neuroprotective Agents; Topiramate | 2005 |
Addicted to Homer?
Topics: Alcoholism; Animals; Carrier Proteins; Choice Behavior; Dopamine; Dose-Response Relationship, Drug; Ethanol; Excitatory Amino Acid Antagonists; Glutamic Acid; Homer Scaffolding Proteins; Mice; Mice, Knockout; Nucleus Accumbens; Reinforcement, Psychology; Reward; Synapses | 2005 |
Pharmacotherapy of alcohol use disorders.
Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Amitriptyline; Antidepressive Agents, Tricyclic; Comorbidity; Disulfiram; Dopamine; Drug Interactions; Ethanol; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Mental Disorders; Naltrexone; Narcotics; Serotonin; Taurine | 2005 |
Preclinical and clinical pharmacology of alcohol dependence.
Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Animals; Disulfiram; Dopamine; GABA Modulators; Glutamic Acid; Humans; Naltrexone; Narcotic Antagonists; Serotonin; Taurine | 2007 |
Approach to the genetics of alcoholism: a review based on pathophysiology.
Topics: Alcohol Dehydrogenase; Alcoholism; Aldehyde-Lyases; Animals; Dopamine Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Genetic Linkage; Glutamic Acid; Humans; Molecular Biology; Neuropeptide Y; Receptors, Dopamine | 2008 |
Glutamatergic substrates of drug addiction and alcoholism.
Topics: Alcoholism; Amphetamines; Animals; Cannabinoids; Cocaine; Disease Models, Animal; Extinction, Psychological; Glutamic Acid; Humans; Narcotics; Neuronal Plasticity; Nicotine; Substance-Related Disorders; Synapses; Synaptic Transmission | 2008 |
Neuropharmacology of alcohol addiction.
Topics: Alcoholism; Animals; Behavior, Addictive; Cannabinoids; Central Nervous System Agents; Corticotropin-Releasing Hormone; Dopamine; Ethanol; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Humans; Neural Pathways; Neuropeptide Y; Neurotransmitter Agents; Opioid Peptides; Receptors, Neurotransmitter; Recurrence; Serotonin; Synaptic Transmission | 2008 |
Recent developments in alcoholism:neuronal ion channels.
Topics: Alcohol Drinking; Alcoholic Intoxication; Alcoholism; Animals; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Ion Channels; Neurons; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1993 |
The role of glutamatergic neurotransmission in the pathophysiology of alcoholism.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Brain; Cell Death; Central Nervous System Depressants; Ethanol; Excitatory Amino Acid Antagonists; Fetal Alcohol Spectrum Disorders; Glutamic Acid; Humans; Neurons; Neurotoxins; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate; Seizures; Synaptic Transmission; Up-Regulation | 1998 |
5 trial(s) available for glutamic acid and Alcoholism
| Article | Year |
|---|---|
N-acetylcysteine does not alter neurometabolite levels in non-treatment seeking adolescents who use alcohol heavily: A preliminary randomized clinical trial.
Topics: Acetylcysteine; Adolescent; Alcohol Drinking; Alcoholism; Double-Blind Method; Ethanol; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutathione; Humans; Male | 2023 |
Influence of n-acetylcysteine maintenance on the pharmacodynamic effects of oral ethanol.
Topics: Acetylcysteine; Adult; Alcoholism; Blood Pressure; Double-Blind Method; Drug-Seeking Behavior; Ethanol; Female; Free Radical Scavengers; Glutamic Acid; Heart Rate; Humans; Male; Middle Aged; Reinforcement, Psychology; Self Administration; Time Factors; Treatment Outcome; Young Adult | 2020 |
Effects of Gabapentin on Dorsal Anterior Cingulate Cortex GABA and Glutamate Levels and Their Associations With Abstinence in Alcohol Use Disorder: A Randomized Clinical Trial.
Topics: Adult; Alcoholism; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Substance Withdrawal Syndrome | 2021 |
Effect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcohol-dependent individuals: a randomized controlled experimental medicine study.
Topics: Acamprosate; Adult; Alcohol Deterrents; Alcoholism; Corticotropin-Releasing Hormone; Creatine; Dexamethasone; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Glucocorticoids; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Taurine | 2010 |
Neurocognitive performance, alcohol withdrawal, and effects of a combination of flumazenil and gabapentin in alcohol dependence.
Topics: Adult; Alcohol Drinking; Alcoholism; Amines; Cognition; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Flumazenil; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Middle Aged; Recurrence; Substance Withdrawal Syndrome; Treatment Outcome | 2011 |
102 other study(ies) available for glutamic acid and Alcoholism
| Article | Year |
|---|---|
Acute stress and alcohol exposure during adolescence result in an anxious phenotype in adulthood: Role of altered glutamate/endocannabinoid transmission mechanisms.
Topics: Alcoholism; Amygdala; Animals; Anxiety; Endocannabinoids; Glutamic Acid; Male; Mental Disorders; Phenotype; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Signal Transduction; Stress, Physiological | 2022 |
Correlation of Antibodies to Neurotransmitters in the Sera of Women with Alcohol Dependence and Depressive Disorders.
Topics: Alcoholism; Autoantibodies; Case-Control Studies; Depressive Disorder; Dopamine; Dysthymic Disorder; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Middle Aged; Norepinephrine; Serotonin | 2021 |
Multimodal neuroimaging of metabotropic glutamate 5 receptors and functional connectivity in alcohol use disorder.
Topics: Alcoholism; Brain; Brain Mapping; Glutamic Acid; Humans; Magnetic Resonance Imaging; Neuroimaging; Receptor, Metabotropic Glutamate 5 | 2022 |
Role of suppressing GLT-1 and xCT in ceftriaxone-induced attenuation of relapse-like alcohol drinking in alcohol-preferring rats.
Topics: Alcohol Drinking; Alcoholism; Amino Acid Transport Systems, Acidic; Animals; Ceftriaxone; Ethanol; Excitatory Amino Acid Transporter 2; Glutamic Acid; Nucleus Accumbens; Rats; Recurrence | 2022 |
Alcohol dependence and the ventral hippocampal influence on alcohol drinking in male mice.
Topics: Alcohol Drinking; Alcoholism; Animals; Ethanol; Glutamic Acid; Hippocampus; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens | 2023 |
Glutamate levels in the ventromedial prefrontal cortex and resting-state functional connectivity within reward circuits in alcohol-dependent patients.
Topics: Alcoholism; Brain; Ethanol; Glutamic Acid; Humans; Magnetic Resonance Imaging; Prefrontal Cortex; Reward | 2023 |
Negative modulation of AMPA receptors bound to transmembrane AMPA receptor regulatory protein γ-8 blunts the positive reinforcing properties of alcohol and sucrose in a brain region-dependent manner in male mice.
Topics: Alcoholism; Animals; Basolateral Nuclear Complex; Calcium Channels; Ethanol; Glutamic Acid; Hippocampus; Locomotion; Male; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Nucleus Accumbens; Receptors, AMPA; Reinforcement, Psychology; Reward; Sucrose | 2023 |
Withdrawal from chronic ethanol exposure increases postsynaptic glutamate function of insular cortex projections to the rat basolateral amygdala.
Topics: Administration, Inhalation; Alcoholism; Animals; Basolateral Nuclear Complex; Central Nervous System Depressants; Cerebral Cortex; Electric Stimulation; Electrophysiological Phenomena; Ethanol; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Ketamine; Male; Neural Pathways; Optogenetics; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome | 2020 |
Abrupt cessation of reboxetine along alcohol deprivation results in alcohol intake escalation after reinstatement of drinking.
Topics: Alcoholism; Animals; Drug-Seeking Behavior; Endocannabinoids; Glutamic Acid; Hippocampus; Male; Prefrontal Cortex; Rats; Rats, Wistar; Reboxetine; Self Administration; Signal Transduction; Substance Withdrawal Syndrome | 2021 |
Elevated thalamic glutamate levels and reduced water diffusivity in alcohol use disorder: Association with impulsivity.
Topics: Adult; Alcoholism; Glutamic Acid; Humans; Impulsive Behavior; Thalamus; Water | 2020 |
The escalation in ethanol consumption following chronic intermittent ethanol exposure is blunted in mice expressing ethanol-resistant GluN1 or GluN2A NMDA receptor subunits.
Topics: Alcohol Drinking; Alcoholism; Animals; Brain; Dose-Response Relationship, Drug; Ethanol; Female; Glutamic Acid; Male; Mice; Nerve Tissue Proteins; Receptors, N-Methyl-D-Aspartate | 2021 |
Altered excitatory transmission in striatal neurons after chronic ethanol consumption in selectively bred crossed high alcohol-preferring mice.
Topics: Alcoholism; Animals; Behavior, Animal; Central Nervous System Depressants; Estrous Cycle; Ethanol; Excitatory Postsynaptic Potentials; Glutamic Acid; Mice; Neostriatum; Neurons; Self Administration; Sex Characteristics; Sex Factors | 2021 |
Negative allosteric modulation of metabotropic glutamate receptor 5 attenuates alcohol self-administration in baboons.
Topics: Alcoholism; Allosteric Regulation; Aminopyridines; Animals; Ethanol; Female; Glutamic Acid; Humans; Papio; Picolinic Acids; Pyridines; Receptor, Metabotropic Glutamate 5; Self Administration; Thiazoles | 2021 |
Prevention of glutamate excitotoxicity in lateral habenula alleviates ethanol withdrawal-induced somatic and behavioral effects in ethanol dependent mice.
Topics: Alcoholism; Amino Acid Transport System X-AG; Animals; Anxiety; Ethanol; Glutamic Acid; Habenula; Male; Mice; Phenols; Piperidines; Substance Withdrawal Syndrome | 2022 |
Glutamate contributes to alcohol hepatotoxicity by enhancing oxidative stress in mitochondria.
Topics: Alcoholism; Animals; Chemical and Drug Induced Liver Injury; Ethanol; Glutamic Acid; Mitochondria, Liver; Oxidative Stress; Proteomics; Rats, Wistar; Reactive Oxygen Species | 2017 |
CRF modulates glutamate transmission in the central amygdala of naïve and ethanol-dependent rats.
Topics: Alcoholism; Animals; Central Amygdaloid Nucleus; Central Nervous System Depressants; Corticotropin-Releasing Hormone; Disease Models, Animal; Ethanol; Glutamic Acid; Male; Neurotransmitter Agents; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Synapses; Synaptic Transmission; Tissue Culture Techniques | 2017 |
Effects of Alcohol Cues on MRS Glutamate Levels in the Anterior Cingulate.
Topics: Adult; Alcohol Drinking; Alcoholism; Cues; Female; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Photic Stimulation; Young Adult | 2018 |
Deficient endocannabinoid signaling in the central amygdala contributes to alcohol dependence-related anxiety-like behavior and excessive alcohol intake.
Topics: Alcoholism; Amidohydrolases; Animals; Anxiety; Central Amygdaloid Nucleus; Central Nervous System Depressants; Endocannabinoids; Ethanol; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice, Inbred C57BL; Monoacylglycerol Lipases; Rats, Wistar | 2018 |
Glutamate concentration in the anterior cingulate cortex in alcohol dependence: association with alcohol withdrawal and exploration of contribution from glutamatergic candidate genes.
Topics: Adult; Aged; Alcoholism; Case-Control Studies; Creatine; Female; GATA4 Transcription Factor; Genetic Association Studies; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Substance Withdrawal Syndrome | 2018 |
phMRI, neurochemical and behavioral responses to psychostimulants distinguishing genetically selected alcohol-preferring from genetically heterogenous rats.
Topics: Alcoholism; Amphetamine; Amygdala; Animals; Brain; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Functional Neuroimaging; gamma-Aminobutyric Acid; Glutamic Acid; Locomotion; Magnetic Resonance Imaging; Microdialysis; Nucleus Accumbens; Rats; Self Administration | 2019 |
Brain Glutamate, GABA, and Glutamine Levels and Associations with Recent Drinking in Treatment-Naïve Individuals with Alcohol Use Disorder Versus Light Drinkers.
Topics: Adult; Alcohol Drinking; Alcoholism; Aspartic Acid; Case-Control Studies; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Male; Proton Magnetic Resonance Spectroscopy; Young Adult | 2019 |
Synaptic adaptations in the central amygdala and hypothalamic paraventricular nucleus associated with protracted ethanol abstinence in male rhesus monkeys.
Topics: Adaptation, Physiological; Alcohol Abstinence; Alcoholism; Animals; Central Amygdaloid Nucleus; Central Nervous System Depressants; Disease Models, Animal; Drug Tolerance; Ethanol; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Inhibitory Postsynaptic Potentials; Macaca mulatta; Male; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques | 2019 |
Evidence for a unique association between fronto-cortical glycine levels and recent heavy drinking in treatment naïve individuals with alcohol use disorder.
Topics: Adult; Alcoholism; Binge Drinking; Female; Frontal Lobe; Glutamic Acid; Glycine; Humans; Male; Proton Magnetic Resonance Spectroscopy; Young Adult | 2019 |
Cessation of fluoxetine treatment increases alcohol seeking during relapse and dysregulates endocannabinoid and glutamatergic signaling in the central amygdala.
Topics: Alcoholism; Animals; Central Amygdaloid Nucleus; Disease Models, Animal; Drug-Seeking Behavior; Endocannabinoids; Fluoxetine; Glutamic Acid; Male; Rats; Rats, Wistar; Recurrence; Selective Serotonin Reuptake Inhibitors; Signal Transduction; Substance Withdrawal Syndrome | 2020 |
Craving in alcohol-dependent patients after detoxification is related to glutamatergic dysfunction in the nucleus accumbens and the anterior cingulate cortex.
Topics: Adult; Alcoholism; Behavior, Addictive; Female; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nucleus Accumbens; Substance Withdrawal Syndrome; Surveys and Questionnaires | 2013 |
Increased brain uptake and oxidation of acetate in heavy drinkers.
Topics: Acetates; Adult; Alcoholism; Blood Glucose; Brain; Case-Control Studies; Female; Glutamic Acid; Glutamine; Humans; Kinetics; Male; Metabolic Networks and Pathways; Middle Aged; Models, Biological; Oxidation-Reduction; Young Adult | 2013 |
Loss of control of alcohol use and severity of alcohol dependence in non-treatment-seeking heavy drinkers are related to lower glutamate in frontal white matter.
Topics: Adult; Alcohol Drinking; Alcoholism; Biomarkers; Diagnostic and Statistical Manual of Mental Disorders; Female; Frontal Lobe; Glutamic Acid; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Fibers, Myelinated; Severity of Illness Index | 2013 |
Increased extracellular glutamate in the nucleus accumbens promotes excessive ethanol drinking in ethanol dependent mice.
Topics: Alcohol Drinking; Alcoholism; Amino Acids; Analysis of Variance; Animals; Aspartic Acid; Bridged Bicyclo Compounds, Heterocyclic; Excitatory Amino Acid Agents; Extracellular Fluid; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Microdialysis; Microinjections; Nucleus Accumbens | 2014 |
Effects of ceftriaxone on chronic ethanol consumption: a potential role for xCT and GLT1 modulation of glutamate levels in male P rats.
Topics: Alcoholism; Amino Acid Transport Systems, Acidic; Animals; Brain; Ceftriaxone; Excitatory Amino Acid Transporter 2; Glutamic Acid; Male; Rats; Up-Regulation | 2014 |
A heuristic model of alcohol dependence.
Topics: Alcoholism; Diazepam; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Models, Biological; Models, Psychological; Neurotransmitter Agents; Substance Withdrawal Syndrome | 2014 |
Effects of ceftriaxone on ethanol intake: a possible role for xCT and GLT-1 isoforms modulation of glutamate levels in P rats.
Topics: Alcohol Drinking; Alcoholism; Amino Acid Transport Systems, Acidic; Animals; Ceftriaxone; Ethanol; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamic Acid; Male; Nucleus Accumbens; Prefrontal Cortex; Protein Isoforms; Rats; Up-Regulation | 2014 |
Hampered long-term depression and thin spine loss in the nucleus accumbens of ethanol-dependent rats.
Topics: Alcoholism; Animals; Central Nervous System Depressants; Dendritic Spines; Dopaminergic Neurons; Ethanol; Glutamic Acid; Long-Term Synaptic Depression; Male; Neuronal Plasticity; Nucleus Accumbens; Organ Culture Techniques; Rats; Rats, Wistar; Synaptic Transmission | 2014 |
A preliminary examination of cortical neurotransmitter levels associated with heavy drinking in posttraumatic stress disorder.
Topics: Adult; Aged; Alcoholism; Aspartic Acid; Cerebral Cortex; Choline; Comorbidity; Creatine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Inositol; Male; Middle Aged; Pilot Projects; Proton Magnetic Resonance Spectroscopy; Stress Disorders, Post-Traumatic | 2014 |
Puerarin protects against damage to spatial learning and memory ability in mice with chronic alcohol poisoning.
Topics: Alcoholism; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Ethanol; gamma-Aminobutyric Acid; Glutamic Acid; Interleukin-1beta; Isoflavones; Male; Maze Learning; Memory Disorders; Mice, Inbred C57BL; Microglia; Neuroprotective Agents; Random Allocation; Spatial Memory; Time Factors; Treatment Outcome; Tumor Necrosis Factor-alpha; Vasodilator Agents | 2015 |
Ceftriaxone attenuates ethanol drinking and restores extracellular glutamate concentration through normalization of GLT-1 in nucleus accumbens of male alcohol-preferring rats.
Topics: Alcohol Deterrents; Alcohol Drinking; Alcoholism; Animals; Ceftriaxone; Central Nervous System Depressants; Disease Models, Animal; Ethanol; Excitatory Amino Acid Transporter 2; Extracellular Space; Glutamate-Ammonia Ligase; Glutamic Acid; Kainic Acid; Male; Microdialysis; Nucleus Accumbens; Rats | 2015 |
Impact of family history of alcoholism on glutamine/glutamate ratio in anterior cingulate cortex in substance-naïve adolescents.
Topics: Adolescent; Aging; Alcoholism; Brain Chemistry; Child; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Impulsive Behavior; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Young Adult | 2015 |
Co-administration of ethanol and nicotine: the enduring alterations in the rewarding properties of nicotine and glutamate activity within the mesocorticolimbic system of female alcohol-preferring (P) rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Drug Combinations; Ethanol; Female; Glutamic Acid; Limbic System; Nicotine; Nucleus Accumbens; Rats; Reward; Self Administration | 2015 |
Glutamatergic and HPA-axis pathway genes in bipolar disorder comorbid with alcohol- and substance use disorders.
Topics: Adolescent; Adult; Age of Onset; Alcoholism; Bipolar Disorder; Cohort Studies; Comorbidity; Female; Glutamic Acid; Humans; Hypothalamo-Hypophyseal System; Male; Middle Aged; Polymorphism, Single Nucleotide; Signal Transduction; Substance-Related Disorders; Young Adult | 2016 |
Autophosphorylation of alpha isoform of calcium/calmodulin-dependent kinase II regulates alcohol addiction-related behaviors.
Topics: Alcoholism; Amygdala; Animals; Behavior, Animal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Central Nervous System Depressants; Drug-Seeking Behavior; Ethanol; Female; Glutamic Acid; Hippocampus; Male; Mice; Motivation; Mutation; Phosphorylation; Synapses | 2017 |
Associations Between Recent Heavy Drinking and Dorsal Anterior Cingulate N-Acetylaspartate and Glutamate Concentrations in Non-Treatment-Seeking Individuals with Alcohol Dependence.
Topics: Adult; Alcohol Drinking; Alcoholism; Aspartic Acid; Biomarkers; Female; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Young Adult | 2016 |
Brain metabolite levels in recently sober individuals with alcohol use disorder: Relation to drinking variables and relapse.
Topics: Adult; Alcohol Abstinence; Alcohol Drinking; Alcoholism; Aspartic Acid; Brain; Choline; Chronic Disease; Creatine; Female; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Recurrence | 2016 |
Anterior Cingulate Glutamate Is Reduced by Acamprosate Treatment in Patients With Alcohol Dependence.
Topics: Acamprosate; Adult; Alcohol Deterrents; Alcoholism; Female; Glutamic Acid; Gyrus Cinguli; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Taurine; Treatment Outcome; Young Adult | 2016 |
Could ethanol-induced alterations in the expression of glutamate transporters in testes contribute to the effect of paternal drinking on the risk of abnormalities in the offspring?
Topics: Alcohol Drinking; Alcoholism; Amino Acid Transport System X-AG; Animals; Biological Transport; Brain; Congenital Abnormalities; Ethanol; Excitatory Amino Acid Transporter 1; Fathers; Female; Glutamic Acid; Glutamine; Humans; Male; Mice; Models, Biological; Paternal Exposure; Risk; Signal Transduction; Testis | 2017 |
Negative Association Between MR-Spectroscopic Glutamate Markers and Gray Matter Volume After Alcohol Withdrawal in the Hippocampus: A Translational Study in Humans and Rats.
Topics: Adult; Alcohol Abstinence; Alcoholism; Animals; Aspartic Acid; Biomarkers; Female; Glutamic Acid; Gray Matter; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Rats; Rats, Wistar; Species Specificity; Substance Withdrawal Syndrome; Translational Research, Biomedical | 2017 |
NMDA Glutamate Receptor Antagonism and the Heritable Risk for Alcoholism: New Insights from a Study of Nitrous Oxide.
Topics: Alcoholism; Glutamic Acid; Humans; N-Methylaspartate; Nitrous Oxide; Receptors, N-Methyl-D-Aspartate | 2017 |
Elevated synaptophysin I in the prefrontal cortex of human chronic alcoholics.
Topics: Adult; Aged; Aged, 80 and over; Alcoholism; Glutamic Acid; Humans; Male; Membrane Glycoproteins; Middle Aged; Neuronal Plasticity; Prefrontal Cortex; Synaptophysin | 2008 |
Repeated alcohol administration during adolescence causes changes in the mesolimbic dopaminergic and glutamatergic systems and promotes alcohol intake in the adult rat.
Topics: Aging; Alcohol-Induced Disorders, Nervous System; Alcoholism; Animals; Animals, Newborn; Central Nervous System Depressants; Disease Models, Animal; Dopamine; Drug Administration Schedule; Ethanol; Glutamic Acid; Limbic System; Male; Neural Pathways; Neuronal Plasticity; Nucleus Accumbens; Rats; Rats, Wistar; Reward; Synaptic Transmission; Ventral Tegmental Area | 2009 |
N-methyl-D-aspartate 2b receptor subtype (NR2B) promoter methylation in patients during alcohol withdrawal.
Topics: Adult; Alcohol-Induced Disorders, Nervous System; Alcoholism; Brain; Brain Chemistry; Cohort Studies; DNA Methylation; DNA Mutational Analysis; Epigenesis, Genetic; Gene Silencing; Genetic Testing; Genotype; Glutamic Acid; Humans; Male; Middle Aged; Promoter Regions, Genetic; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome | 2009 |
Neuro-inflammation induced in the hippocampus of 'binge drinking' rats may be mediated by elevated extracellular glutamate content.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Amino Acids; Animals; Biogenic Monoamines; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Extracellular Fluid; Female; Glutamic Acid; Hippocampus; Histocompatibility Antigens Class II; Hydroxyindoleacetic Acid; Macrophages, Alveolar; Microdialysis; Microglia; Nitric Oxide Synthase Type II; Rats; Rats, Wistar | 2009 |
Distinct forms of Gq-receptor-dependent plasticity of excitatory transmission in the BNST are differentially affected by stress.
Topics: Alcoholism; Animals; Ethanol; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Long-Term Synaptic Depression; Male; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Norepinephrine; Receptor, Angiotensin, Type 1; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate; Septal Nuclei; Signal Transduction; Stress, Physiological | 2010 |
Alcohol-seeking behavior is associated with increased glutamate transmission in basolateral amygdala and nucleus accumbens as measured by glutamate-oxidase-coated biosensors.
Topics: Alcohol Drinking; Alcoholism; Amino Acid Oxidoreductases; Amygdala; Animals; Biosensing Techniques; Brain Mapping; Cues; Extinction, Psychological; Glutamic Acid; Male; Motivation; Nucleus Accumbens; Rats; Rats, Wistar; Self Administration; Synaptic Transmission | 2011 |
Perturbation of the glutamate-glutamine system in alcohol dependence and remission.
Topics: Adult; Alcoholism; Analysis of Variance; Brain; Chi-Square Distribution; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Metabolic Diseases; Middle Aged; Recurrence; Tritium | 2011 |
Pathway based analysis of genotypes in relation to alcohol dependence.
Topics: Alcoholism; gamma-Aminobutyric Acid; Gene Regulatory Networks; Genotype; Glutamic Acid; Humans; Linkage Disequilibrium; Polymorphism, Single Nucleotide; Signal Transduction; Transcriptome | 2012 |
[About the NMDA-system again].
Topics: Alcoholism; Alzheimer Disease; Animals; Antipsychotic Agents; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synapses | 2011 |
Translational magnetic resonance spectroscopy reveals excessive central glutamate levels during alcohol withdrawal in humans and rats.
Topics: Adult; Alcoholism; Animals; Case-Control Studies; Ethanol; Female; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Rats; Substance Withdrawal Syndrome | 2012 |
Disruptions in serotonergic regulation of cortical glutamate release in primate insular cortex in response to chronic ethanol and nursery rearing.
Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Animals; Central Nervous System Depressants; Cerebral Cortex; Chronic Disease; Disease Models, Animal; Ethanol; Female; Glutamic Acid; Macaca mulatta; Male; Maternal Deprivation; Receptors, Serotonin; Stress, Psychological | 2012 |
Glutamate, GABA, and other cortical metabolite concentrations during early abstinence from alcohol and their associations with neurocognitive changes.
Topics: Adult; Alcoholism; Algorithms; Brain Chemistry; Cerebral Cortex; Cognition; Diagnostic and Statistical Manual of Mental Disorders; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Learning; Magnetic Resonance Spectroscopy; Male; Memory; Memory, Short-Term; Psychiatric Status Rating Scales; Psychomotor Performance; Socioeconomic Factors | 2012 |
Some possible genetic parallels across alcoholism, bipolar disorder and schizophrenia.
Topics: Alcoholism; Bipolar Disorder; Catecholamines; Chromosome Deletion; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 22; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Schizophrenia | 2003 |
[Glutamic treatment in certain psychic complications of chronic alcoholism (predelerium & delirium tremens); concerning the gamma-ethyl ester of glutamic acid].
Topics: Alcohol Withdrawal Delirium; Alcoholism; Esters; Glutamates; Glutamic Acid; Humans; Mental Disorders; Psychoses, Alcoholic; Psychotic Disorders | 1957 |
[SOME CLINICAL RESULTS OF THE TREATMENT OF ALCOHOLISM WITH L-GLUTAMIC ACID MONOAMIDE].
Topics: Alcoholism; Biomedical Research; Glutamates; Glutamic Acid | 1964 |
[Observations on the behavior of the blood proteins in a group of tuberculotic alcoholics under treatment with glutamic acid esters].
Topics: Alcoholics; Alcoholism; Blood Proteins; Esters; Glutamic Acid; Humans; Thoracic Cavity; Tuberculosis; Tuberculosis, Pulmonary | 1962 |
Imbalance between neuroexcitatory and neuroinhibitory amino acids causes craving for ethanol.
Topics: Alcoholism; Animals; Behavior, Addictive; Brain; Drug Tolerance; Ethanol; Excitatory Amino Acids; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Models, Animal; Neurotransmitter Agents; Rats; Substance Withdrawal Syndrome | 2004 |
Effects of NMDA glutamate receptor antagonist drugs on the volitional consumption of ethanol by a genetic drinking rat.
Topics: Alcohol Drinking; Alcohol-Induced Disorders, Nervous System; Alcoholism; Amino Acids, Cyclic; Animals; Brain; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ethanol; Excitatory Amino Acid Antagonists; Female; Genetic Predisposition to Disease; Glutamic Acid; Isoquinolines; Male; Motor Activity; Pyrrolidinones; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Volition | 2004 |
Pharmacological and anatomical evidence for an interaction between mGluR5- and GABA(A) alpha1-containing receptors in the discriminative stimulus effects of ethanol.
Topics: Alcoholism; Animals; Diazepam; Discrimination, Psychological; Disease Models, Animal; Drug Interactions; Ethanol; Excitatory Amino Acid Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Male; Neurons; Pentobarbital; Pyridines; Rats; Rats, Long-Evans; Receptor, Metabotropic Glutamate 5; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Synaptic Transmission; Telencephalon | 2005 |
The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption.
Topics: Acamprosate; Alcohol Deterrents; Alcohol Drinking; Alcoholism; Amino Acid Transport System X-AG; Animals; Biological Clocks; Cell Cycle Proteins; Cocaine; Cocaine-Related Disorders; Glutamic Acid; Humans; Mice; Nuclear Proteins; Period Circadian Proteins; Taurine; Time Factors; Transcription Factors | 2005 |
Clock reset for alcoholism.
Topics: Alcohol Drinking; Alcoholism; Animals; Biological Clocks; Cell Cycle Proteins; Cocaine; Cocaine-Related Disorders; Glutamic Acid; Humans; Mice; Nuclear Proteins; Period Circadian Proteins; Transcription Factors | 2005 |
The metabotropic glutamate 5 receptor antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]-pyridine reduces ethanol self-administration in multiple strains of alcohol-preferring rats and regulates olfactory glutamatergic systems.
Topics: Alcohol Drinking; Alcoholism; Animals; Autoradiography; Biomarkers; Brain Chemistry; Conditioning, Operant; Depression; Drinking; Glutamic Acid; In Situ Hybridization; Male; Motor Activity; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Smell; Swimming; Thiazoles | 2005 |
N-methyl-D-aspartate and group I metabotropic glutamate receptors are involved in the expression of ethanol-induced sensitization in mice.
Topics: Acamprosate; Alcoholism; Animals; Brain; Cyclopentanes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Glutamic Acid; Male; Mice; Motor Activity; N-Methylaspartate; Pyridines; Quinolines; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior; Synaptic Transmission; Taurine; Thiazoles | 2006 |
Actions of acute and chronic ethanol on presynaptic terminals.
Topics: Alcoholic Intoxication; Alcoholism; Animals; Brain; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Membrane Potentials; Neuropeptides; Receptors, Presynaptic; Synaptic Vesicles | 2006 |
From blue states to up states: a regional view of NMDA-ethanol interactions.
Topics: Alcoholism; Amygdala; Animals; Brain; Drug Tolerance; Ethanol; Glutamic Acid; Humans; Long-Term Potentiation; Neuronal Plasticity; Prefrontal Cortex; Receptors, N-Methyl-D-Aspartate; Septal Nuclei; Stress, Psychological; Substance-Related Disorders; Synapses; Tissue Culture Techniques | 2006 |
Structural and functional modifications in glutamateric synapses following prolonged ethanol exposure.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Amygdala; Animals; Brain; Brain Mapping; Carrier Proteins; Ethanol; Glutamic Acid; Homer Scaffolding Proteins; Humans; Mice; Neuronal Plasticity; Nucleus Accumbens; Rats; Receptors, N-Methyl-D-Aspartate; Synapses | 2006 |
Clinical correlates of quantitative EEG alterations in alcoholic patients.
Topics: Adult; Age Factors; Aged; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders, Nervous System; Alcoholism; Atrophy; Benzodiazepines; Brain Damage, Chronic; Central Nervous System Depressants; Cerebral Cortex; Drug Interactions; Electroencephalography; Ethanol; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glutamic Acid; Hallucinations; Humans; Male; Middle Aged; Models, Neurological; Nerve Degeneration; Neurotoxins | 2006 |
Behavioral and neurochemical interactions between Group 1 mGluR antagonists and ethanol: potential insight into their anti-addictive properties.
Topics: Alcohol Deterrents; Alcoholism; Animals; Chromones; Conditioning, Classical; Dopamine; Dose-Response Relationship, Drug; Ethanol; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Motor Activity; Nucleus Accumbens; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate | 2006 |
Combined application of behavior genetics and microarray analysis to identify regional expression themes and gene-behavior associations.
Topics: Alcoholism; Animals; Anxiety Disorders; Behavior, Animal; Brain; Brain Chemistry; Brain Mapping; Chromosome Mapping; Gene Expression Profiling; Gene Expression Regulation; Genetic Predisposition to Disease; Genetics, Behavioral; Genomics; Glutamic Acid; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Oligonucleotide Array Sequence Analysis; Phenotype; Signal Transduction; Species Specificity | 2006 |
Glutamate-dopamine cotransmission and reward processing in addiction.
Topics: Alcoholism; Animals; Cues; Dopamine; Glutamic Acid; Haplorhini; Humans; Neurons; Prefrontal Cortex; Reward; Synaptic Transmission; Ventral Tegmental Area; Vesicular Glutamate Transport Proteins | 2006 |
Chronic alcohol drinking alters neuronal dendritic spines in the brain reward center nucleus accumbens.
Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Animals; Central Nervous System Depressants; Chronic Disease; Dendritic Spines; Ethanol; Glutamic Acid; Image Cytometry; Immunohistochemistry; Male; Microscopy, Confocal; Nucleus Accumbens; Rats; Receptors, N-Methyl-D-Aspartate; Reward; Substance-Related Disorders; Synapses; Synaptic Transmission | 2007 |
Accumbens neurochemical adaptations produced by binge-like alcohol consumption.
Topics: Alcohol Drinking; Alcoholism; Animals; Central Nervous System Depressants; Disease Models, Animal; Dopamine; Ethanol; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Microdialysis; Nucleus Accumbens; Reproducibility of Results; Serotonin; Time Factors | 2007 |
Alteration of brain metabolites in young alcoholics without structural changes.
Topics: Adult; Alcoholism; Brain; Brain Mapping; Choline; Creatine; Female; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Protons | 2007 |
Smoking and alcoholism target genes associated with plasticity and glutamate transmission in the human ventral tegmental area.
Topics: Alcoholism; Base Sequence; Blotting, Western; Case-Control Studies; DNA Probes; Ethanol; Female; Gene Expression Profiling; Glutamic Acid; Humans; Male; Neuronal Plasticity; Nicotine; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; RNA, Messenger; Smoking; Synaptic Transmission; Ventral Tegmental Area; Vesicular Glutamate Transport Protein 1; Vesicular Glutamate Transport Protein 2 | 2008 |
Synergistic effects of the dopaminergic and glutamatergic system on hippocampal volume in alcohol-dependent patients.
Topics: Adult; Alcoholism; Alleles; Catechol O-Methyltransferase; Dopamine; Female; Genetic Variation; Genotype; Glutamic Acid; Hippocampus; Humans; Image Processing, Computer-Assisted; Long-Term Potentiation; Magnetic Resonance Imaging; Male; Middle Aged; Phenotype; Polymorphism, Single Nucleotide; Psychiatric Status Rating Scales; Receptors, Metabotropic Glutamate | 2008 |
Regional effects of ethanol on glutamate levels, uptake and release in slice and synaptosome preparations from rat brain.
Topics: Alcohol Drinking; Alcohol Withdrawal Delirium; Alcoholism; Animals; Corpus Striatum; Culture Techniques; Ethanol; Frontal Lobe; Glutamates; Glutamic Acid; Hippocampus; Humans; Male; Rats; Rats, Inbred Strains; Synaptic Transmission; Synaptosomes | 1983 |
Attenuation of glutamate-induced neurotoxicity in chronically ethanol-exposed cerebellar granule cells by NMDA receptor antagonists and ganglioside GM1.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Animals; Animals, Newborn; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; G(M1) Ganglioside; Glutamic Acid; Kynurenic Acid; Neurons; Pipecolic Acids; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Up-Regulation | 1995 |
Amino acid neurotransmitters in alcohol withdrawal.
Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Amino Acids; Aspartic Acid; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Humans; Male; Neurologic Examination | 1994 |
Rewarding and aversive effects of ethanol: interplay of GABA, glutamate and dopamine.
Topics: Alcoholism; Animals; Aversive Therapy; Dizocilpine Maleate; Dopamine; Electrophysiology; Ethanol; gamma-Aminobutyric Acid; Glutamic Acid; Limbic System; Male; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reward; Synaptic Transmission | 1993 |
Stability of [3H]MK-801 binding sites following chronic ethanol consumption.
Topics: Alcoholism; Animals; Autoradiography; Dizocilpine Maleate; Glutamic Acid; Hippocampus; Male; Mental Recall; Rats; Receptors, N-Methyl-D-Aspartate; Up-Regulation | 1994 |
Regional and subunit specific changes in NMDA receptor mRNA and immunoreactivity in mouse brain following chronic ethanol ingestion.
Topics: Alcoholism; Animals; Brain; Cerebellum; Cerebral Cortex; Dizocilpine Maleate; Glutamic Acid; Hippocampus; Macromolecular Substances; Male; Mice; Mice, Inbred C57BL; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Substance Withdrawal Syndrome | 1996 |
The effect of tilsuprost on the liver mitochondria in taurocholate pancreatitis in rats with antecedent acute ethanol abuse.
Topics: Adenosine Triphosphatases; Alcoholism; Animals; Epoprostenol; Glutamic Acid; Malates; Male; Mitochondria, Liver; Oxidative Phosphorylation; Oxygen; Pancreatitis; Rats; Rats, Wistar; Taurocholic Acid | 1996 |
In vivo links between neurochemistry and behavioral effects of ethanol.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Animals; Behavior, Animal; Brain; Dopamine; Dose-Response Relationship, Drug; Ethanol; Glutamic Acid; Humans; Membrane Potentials; Neurons; Nucleus Accumbens | 1996 |
Acute and chronic alcohol injections increase taurine in the nucleus accumbens.
Topics: Alcoholism; Animals; Ethanol; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Injections, Intraperitoneal; Male; Nucleus Accumbens; Rats; Rats, Wistar; Taurine | 1994 |
Free radical production during ethanol intoxication, dependence, and withdrawal.
Topics: Alcohol Withdrawal Delirium; Alcoholic Intoxication; Alcoholism; Animals; Brain; Free Radicals; Glutamate-Ammonia Ligase; Glutamic Acid; Male; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 1997 |
Prenatal ethanol exposure enhances glutamate release stimulated by quisqualate in rat cerebellar granule cell cultures.
Topics: Alcoholism; Amino Acids; Animals; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Ethanol; Female; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurons; Potassium Chloride; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1998 |
Teaching the brain to take drugs.
Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Animals; Behavior, Addictive; Brain; Cocaine; Cocaine-Related Disorders; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Rats; Receptors, Glutamate; Substance-Related Disorders; Synaptic Transmission; Taurine | 1998 |
Central effects of acamprosate: part 1. Acamprosate blocks the glutamate increase in the nucleus accumbens microdialysate in ethanol withdrawn rats.
Topics: Acamprosate; Alanine; Alcohol Deterrents; Alcoholism; Animals; Arginine; Aspartic Acid; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Glutamic Acid; Male; Nucleus Accumbens; Rats; Rats, Wistar; Taurine | 1998 |
[Regional cerebral blood flow and cerebrospinal fluid amino acid analysis in elderly dementia].
Topics: Alcoholism; Alzheimer Disease; Amino Acids; Aminobutyrates; Cerebrovascular Circulation; Chronic Disease; Dementia, Vascular; Glutamic Acid; Humans; Middle Aged; Regional Blood Flow | 1998 |
Glutamate receptors in the cingulate cortex, hippocampus, and cerebellar vermis of alcoholics.
Topics: 2-Amino-5-phosphonovalerate; Aged; Alcoholism; Cerebellar Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Gyrus Cinguli; Hippocampus; Humans; Middle Aged; Receptors, Glutamate | 1999 |
Taurine blocks the glutamate increase in the nucleus accumbens microdialysate of ethanol-dependent rats.
Topics: Alcoholism; Animals; Arginine; Central Nervous System Depressants; Ethanol; gamma-Aminobutyric Acid; Glutamic Acid; Male; Nucleus Accumbens; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Taurine | 2000 |
Genetic variation of the glutamate transporter EAAT2 gene and vulnerability to alcohol dependence.
Topics: Adult; Alcoholism; Alleles; Excitatory Amino Acid Transporter 2; Female; Gene Frequency; Genetic Variation; Genotype; Glutamic Acid; Humans; Male; Personality Tests; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Receptors, Neurotransmitter | 2000 |
Ethanol dependence has limited effects on GABA or glutamate transporters in rat brain.
Topics: Alcoholism; Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Brain; Carrier Proteins; Central Nervous System Depressants; Ethanol; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Male; Membrane Proteins; Membrane Transport Proteins; Organic Anion Transporters; Rats; Rats, Sprague-Dawley; Symporters | 2001 |
Investigation of the therapeutic efficacy of a taurine analogue during the initial stages of ethanol detoxification: preliminary studies in chronic alcohol abusers.
Topics: Acamprosate; Alcoholism; Amino Acids; Chlordiazepoxide; Chronic Disease; Ethanol; GABA Modulators; Glutamic Acid; Humans; Molecular Structure; Taurine | 2000 |
Ischemia-induced glutamate release in rat frontoparietal cortex after chronic alcohol and withdrawal.
Topics: Alcoholism; Animals; Aspartic Acid; Central Nervous System Depressants; Dialysis Solutions; Ethanol; Glutamic Acid; Ischemic Attack, Transient; Male; Microdialysis; Parietal Lobe; Rats; Rats, Wistar; Substance Withdrawal Syndrome | 2002 |
Ethanol-induced inhibition of testosterone biosynthesis in rat Leydig cells: role of mitochondrial substrate shuttles and citrate.
Topics: Alcoholism; Animals; Cells, Cultured; Citrates; Ethanol; Glutamates; Glutamic Acid; Leydig Cells; Male; Mitochondria; Pyruvates; Pyruvic Acid; Rats; Testosterone | 1990 |
Glutamate receptor changes in brain synaptic membranes from human alcoholics.
Topics: Alcoholism; Glutamates; Glutamic Acid; Hippocampus; Humans; Piperazines; Radioligand Assay; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Membranes | 1990 |