glutamic acid and Alcohol Drinking

glutamic acid has been researched along with Alcohol Drinking in 74 studies

Research

Studies (74)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (4.05)	18.7374
1990's	7 (9.46)	18.2507
2000's	11 (14.86)	29.6817
2010's	45 (60.81)	24.3611
2020's	8 (10.81)	2.80

Authors

Authors	Studies
Alasmari, F; Althobaiti, YS; Das, SC; Hammad, AM; Sari, Y	1
Abou-Gharbia, M; Alhaddad, H; Bell, RL; Childers, W; Melenski, E; Sari, Y; Wong, W	1
Becker, HC; Griffin, WC; Lopez, MF; Woodward, JJ	1
Brady, KT; Browning, BD; Ferguson, PL; Gray, KM; Green, R; Kirkland, AE; Liu, H; Maralit, AM; Meyerhoff, DJ; Miranda, R; Prisciandaro, JJ; Squeglia, LM; Tomko, RL	1
Blaker, AL; Moore, ER; Yamamoto, BK	1
Agostini, JF; Baldin, SL; Bernardo, HT; Costa, NLF; de Pieri Pickler, K; Manenti, MC; Mendes, NV; Rico, EP	1
Gioia, DA; Homanics, GE; Lopez, M; Woodward, JJ; Zamudio, PA	1
Arends, MA; Elvig, SK; Koob, GF; McGinn, MA; Smith, C; Vendruscolo, LF	1
DiBerto, JF; Kash, TL; Levine, OB; Miller, JD; Pleil, KE; Rinker, JA; Rivera-Irizarry, JK; Rowson, SA; Skelly, MJ; Thiele, TE	1
Adamski, J; Artati, A; Borggrefe, J; Franke, A; Freitag-Wolf, S; Höpfner, T; Hov, JR; Illig, T; Jacobs, G; Jensen, MK; Karlsen, TH; Kastenmüller, G; Koch, M; Krawczak, M; Lieb, W; Markus, MRP; Nöthlings, U; Nothnagel, M; Pick, J; Römisch-Margl, W; Schlesinger, S; Schreiber, S; Siegert, S	1
Althobaiti, YS; Das, SC; Hammad, AM; Sari, Y	1
Bekker, A; Fu, R; Kang, S; Li, J; Shah, A; Ye, JH; Zhang, H; Zuo, W	1
Bell, RL; Ding, ZM; Hauser, SR; Ingraham, CM; Lasek, AW; McBride, WJ	1
Nobrega, JN; Nona, CN	1
Cheng, H; Dharmadhikari, S; Dydak, U; Finn, P; Kellar, D; Lake, A; Newman, S; Rebec, GV	1
Auriola, SOK; Hanhineva, KJ; Heinonen, ST; Kärkkäinen, OK; Lehikoinen, AI; Lehtonen, MAS	1
Choi, IY; Hui, D; Lee, P; Michaelis, EK; Wang, WT	1
Anton, RF; Brown, TR; Prescot, AP; Prisciandaro, JJ; Renshaw, PF; Schacht, JP	2
Demirakca, T; Ende, G; Frischknecht, U; Hermann, D; Hoerst, M; Mann, K; Rabinstein, J; Tunc-Skarka, N; Vollstädt-Klein, S; Weber-Fahr, W; Wichert, S	1
Alvarez, VA; Bock, R; Cuzon Carlson, VC; Lovinger, DM; Sherazee, N; Sprow, GM; Thiele, TE; Wilcox, MV	1
Hirouchi, M; Oka, M; Oyama, T; Sugahara, S; Tamura, M	1
Becker, HC; Griffin, WC; Haun, HL; Hazelbaker, CL; Ramachandra, VS	1
Augier, E; Barbier, E; Edenberg, HJ; Enoch, MA; Feng, A; Flanigan, M; Goldman, D; Heilig, M; Hodgkinson, CA; Karlsson, C; Kimura, M; Liang, T; Lovinger, DM; Shen, PH; Tapocik, JD; Xiong, W; Yuan, Q; Zhou, Z	1
Barry, SM; Bechtholt, AJ; Cohen, BM; John, CS; Ongür, D; Smith, KL; Sypek, EI	1
Alhaddad, H; Das, SC; Sari, Y	1
Fredriksson, I; Jardemark, K; Jayaram-Lindström, N; Nylander, E; Nyström, E; Steensland, P; Wirf, M	1
Bhad, R; Hazari, N	1
Agoglia, AE; Faccidomo, SP; Galunas, C; Hodge, CW; Kash, TL; Li, C; Psilos, K; Salling, MC; Spanos, M	1
Cabrera, R; Estrella, CR; García, S; Lara, HE; Yunes, R	1
Das, SC; Hristov, AM; Sari, Y; Yamamoto, BK	1
Acosta, GB; Andreu, M; Grosman, M; Odeon, MM; Yamauchi, L	1
Chitty, KM; Haber, PS; Hermens, DF; Hickie, IB; Lagopoulos, J; Lee, RS; Naismith, SL; Tickell, A	1
Deehan, GA; Hauser, SR; Knight, CP; McBride, WJ; Rodd, ZA; Toalston, JE; Truitt, WA; Waeiss, RA	1
Ciccocioppo, R; Heilig, M; Herman, MA; Kirson, D; Luu, G; Oleata, CS; Roberto, M; Varodayan, FP	1
González-Sepúlveda, M; Marcos, J; Pozo, OJ; Valverde, O	1
Blanco, E; Castilla-Ortega, E; Estivill-Torrús, G; Pavón, FJ; Pedraza, C; Rodríguez de Fonseca, F; Sánchez-Marín, L; Santín, L; Serrano, A; Suárez, J	1
Alshehri, FS; Althobaiti, YS; Das, SC; Sari, Y	1
Carr, RA; Colrain, IM; Mayer, D; Pfefferbaum, A; Rohlfing, T; Sullivan, EV; Zahr, NM	1
Frazier, CJ; Kelly, K; Knackstedt, LA; Pati, D; Stennett, B	1
Donald, KA; Howells, FM; Narr, KL; Roos, A; Stein, DJ; Woods, RP; Zar, HJ	1
Biernacka, JM; Choi, DS; Feeder, SE; Frye, MA; Geske, J; Gunderson, LJ; Hinton, DJ; Karpyak, VM; Port, JD	1
Balcar, VJ; Kashem, MA; Lee, A; Pow, DV; Šerý, O	1
Gould, AT; Goulding, SP; Klugmann, M; Lominac, KD; Miller, BW; Obara, I; Szumlinski, KK	1
Cleva, RM; Gass, JT; Olive, MF; Sinclair, CM; Widholm, JJ	1
Choi, DS; Hinton, DJ; Lee, MR; Macura, SI; Mishra, PK; Port, JD; Wu, J	1
Bakalkin, G; Chefer, V; Kuzmin, A; Meis, J; Shippenberg, T; Wang, G	1
Choi, DS; Choi, S; Hammack, N; Hinton, DJ; Kim, T; Lee, MR; Nam, HW; Wu, J; Yin, JC; Zhu, Y	1
Anton, RF; Baros, AM; Latham, PK; Myrick, H; Randall, PK; Schacht, JP; Waid, LR; Wright, TM	1
Czachowski, CL; Delory, MJ; Pope, JD	1
Cameron, A; Gong, Z; Harrington, J; Lockridge, A; Newland, B; Romero, G; Yuan, LL	1
Barson, JR; Chen, A; Chen, YW; Hoebel, BG; Leibowitz, SF	1
Carrisoza, R; Méndez-Díaz, M; Prospéro-García, O; Romano-López, A; Ruiz-Contreras, AE	1
Joyner, PW; McMillen, BA; Parmar, CA; Tyer, WE; Williams, HL	1
Abarca, C; Albrecht, U; Depner, M; Holzberg, D; Lascorz, J; Lathrop, M; Magnone, MC; Matsuda, F; Pendyala, G; Sanchis-Segura, C; Schreiber, S; Schumann, G; Soyka, M; Spanagel, R; Zghoul, T	1
Bart, G; Kreek, MJ; Yuferov, V	1
Gonzales, RA; Jaworski, JN	1
Cowen, MS; Djouma, E; Lawrence, AJ	1
Hyytiä, P; Kiianmaa, K; Ojanen, SP; Palmén, M	1
Bowers, MS; Diab, ME; Friedman, R; Henze, LM; Lominac, KD; Szumlinski, KK	1
Adams, CL; Cowen, MS; Lawrence, AJ; Short, JL	1
Endo, T; Fujiwara, Y; Mizutani, R; Sanbe, A; Takagi, N; Takeo, S; Tanoue, A; Tsujimoto, G; Yamauchi, J	1
Kapasova, Z; Szumlinski, KK	1
Ahn, YS; Claus, D; Kim, JS; Kornhuber, ME	1
Cummins, JT; Keller, E; von Hungen, K	1
Harris, RA; Sanna, E	1
Daniell, LC; Phillips, TJ	1
Bustos, G; Gysling, K; Labarca, R; Seguel, M; Sepúlveda, C	1
Bradberry, CW; Selim, M	1
Atkins, B; Brien, JF; Chestnut, DH; Dexter, F; Hrdy, J; Penning, DH; Poduska, D; Reynolds, JD	1
Hurley, TD; Steinmetz, CG; Weiner, H; Xie, P	1
Colombo, G; De Witte, P; Lallemand, F; Quertemont, E	1
Angeletti, S; Ciccocioppo, R; Massi, M; Panocka, I	1

Reviews

5 review(s) available for glutamic acid and Alcohol Drinking

Article	Year
Tolerance to alcohol: A critical yet understudied factor in alcohol addiction. Pharmacology, biochemistry, and behavior, 2021, Volume: 204 Topics: Alcohol Drinking; Alcoholism; Animals; Behavior, Addictive; Brain; Disease Models, Animal; Dopamine; Drug Tolerance; Ethanol; Female; Glutamic Acid; Humans; Male; Mice; Neurobiology; Norepinephrine; Rats; Serotonin; Sex Characteristics	2021
The lateral habenula and alcohol: Role of glutamate and M-type potassium channels. Pharmacology, biochemistry, and behavior, 2017, Volume: 162 Topics: Alcohol Drinking; Alcoholism; Animals; Ethanol; Glutamic Acid; Habenula; Humans; Nerve Net; Potassium Channels	2017
Alcohol and glutamate. Alcohol health and research world, 1997, Volume: 21, Issue:2 Topics: Alcohol Drinking; Animals; Ethanol; Glutamic Acid; Humans; Receptors, Glutamate	1997
Recent developments in alcoholism:neuronal ion channels. Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism, 1993, Volume: 11 Topics: Alcohol Drinking; Alcoholic Intoxication; Alcoholism; Animals; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Ion Channels; Neurons; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission	1993
Nociceptin/orphanin FQ and drugs of abuse. Peptides, 2000, Volume: 21, Issue:7 Topics: Alcohol Drinking; Analgesics, Opioid; Animals; Behavior; Brain; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Heroin; Models, Biological; Morphine; Narcotic Antagonists; Narcotics; Neurotransmitter Agents; Nociceptin; Nociceptin Receptor; Opioid Peptides; Rats; Rats, Mutant Strains; Receptors, Opioid; Serotonin; Substance-Related Disorders; Time Factors; Vasodilator Agents	2000

Trials

2 trial(s) available for glutamic acid and Alcohol Drinking

Article	Year
N-acetylcysteine does not alter neurometabolite levels in non-treatment seeking adolescents who use alcohol heavily: A preliminary randomized clinical trial. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2023, Volume: 48, Issue:8 Topics: Acetylcysteine; Adolescent; Alcohol Drinking; Alcoholism; Double-Blind Method; Ethanol; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutathione; Humans; Male	2023
Neurocognitive performance, alcohol withdrawal, and effects of a combination of flumazenil and gabapentin in alcohol dependence. Alcoholism, clinical and experimental research, 2011, Volume: 35, Issue:11 Topics: Adult; Alcohol Drinking; Alcoholism; Amines; Cognition; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Flumazenil; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Middle Aged; Recurrence; Substance Withdrawal Syndrome; Treatment Outcome	2011

Article

Year

N-acetylcysteine does not alter neurometabolite levels in non-treatment seeking adolescents who use alcohol heavily: A preliminary randomized clinical trial.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2023, Volume: 48, Issue:8

Topics: Acetylcysteine; Adolescent; Alcohol Drinking; Alcoholism; Double-Blind Method; Ethanol; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutathione; Humans; Male

2023

Neurocognitive performance, alcohol withdrawal, and effects of a combination of flumazenil and gabapentin in alcohol dependence.

Alcoholism, clinical and experimental research, 2011, Volume: 35, Issue:11

Topics: Adult; Alcohol Drinking; Alcoholism; Amines; Cognition; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Flumazenil; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Middle Aged; Recurrence; Substance Withdrawal Syndrome; Treatment Outcome

2011

Other Studies

67 other study(ies) available for glutamic acid and Alcohol Drinking

Article	Year
Role of suppressing GLT-1 and xCT in ceftriaxone-induced attenuation of relapse-like alcohol drinking in alcohol-preferring rats. Addiction biology, 2022, Volume: 27, Issue:4 Topics: Alcohol Drinking; Alcoholism; Amino Acid Transport Systems, Acidic; Animals; Ceftriaxone; Ethanol; Excitatory Amino Acid Transporter 2; Glutamic Acid; Nucleus Accumbens; Rats; Recurrence	2022
Effects of a Novel Beta Lactam Compound, MC-100093, on the Expression of Glutamate Transporters/Receptors and Ethanol Drinking Behavior of Alcohol-Preferring Rats. The Journal of pharmacology and experimental therapeutics, 2022, Volume: 383, Issue:3 Topics: Alcohol Drinking; Animals; beta-Lactams; Ethanol; Excitatory Amino Acid Transporter 2; Glutamic Acid; Male; Nucleus Accumbens; Peroxisome Proliferator-Activated Receptors; Rats	2022
Alcohol dependence and the ventral hippocampal influence on alcohol drinking in male mice. Alcohol (Fayetteville, N.Y.), 2023, Volume: 106 Topics: Alcohol Drinking; Alcoholism; Animals; Ethanol; Glutamic Acid; Hippocampus; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens	2023
Serial exposure to ethanol drinking and methamphetamine enhances glutamate excitotoxicity. Journal of neurochemistry, 2019, Volume: 151, Issue:6 Topics: Alcohol Drinking; Animals; Drug Synergism; Ethanol; Excitatory Amino Acid Transporter 1; Extracellular Space; Glutamic Acid; Male; Methamphetamine; Microdialysis; Rats; Rats, Sprague-Dawley	2019
Ceftriaxone Attenuated Anxiety-Like Behavior and Enhanced Brain Glutamate Transport in Zebrafish Subjected to Alcohol Withdrawal. Neurochemical research, 2020, Volume: 45, Issue:7 Topics: Alcohol Drinking; Animals; Anxiety; Brain; Ceftriaxone; Ethanol; Glutamic Acid; Oxidative Stress; Substance Withdrawal Syndrome; Zebrafish	2020
The escalation in ethanol consumption following chronic intermittent ethanol exposure is blunted in mice expressing ethanol-resistant GluN1 or GluN2A NMDA receptor subunits. Psychopharmacology, 2021, Volume: 238, Issue:1 Topics: Alcohol Drinking; Alcoholism; Animals; Brain; Dose-Response Relationship, Drug; Ethanol; Female; Glutamic Acid; Male; Mice; Nerve Tissue Proteins; Receptors, N-Methyl-D-Aspartate	2021
The paraventricular thalamus provides a polysynaptic brake on limbic CRF neurons to sex-dependently blunt binge alcohol drinking and avoidance behavior in mice. Nature communications, 2021, 08-23, Volume: 12, Issue:1 Topics: Alcohol Drinking; Animals; Anxiety; Avoidance Learning; Behavior, Animal; Corticotropin-Releasing Hormone; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Inhibitory Postsynaptic Potentials; Integrases; Limbic System; Male; Mice, Inbred C57BL; Neurons; Phenotype; Septal Nuclei; Sex Characteristics; Synapses; Thalamus	2021
Serum metabolomic profiling highlights pathways associated with liver fat content in a general population sample. European journal of clinical nutrition, 2017, Volume: 71, Issue:8 Topics: Aged; Alcohol Drinking; Biological Specimen Banks; Biomarkers; Cohort Studies; Computational Biology; Cross-Sectional Studies; Dipeptides; Expert Systems; Fatty Liver, Alcoholic; Female; Glutamic Acid; Humans; Lipid Metabolism; Liver; Magnetic Resonance Imaging; Male; Metabolomics; Middle Aged; Non-alcoholic Fatty Liver Disease; Self Report; Severity of Illness Index	2017
Effects of repeated cocaine exposure and withdrawal on voluntary ethanol drinking, and the expression of glial glutamate transporters in mesocorticolimbic system of P rats. Molecular and cellular neurosciences, 2017, Volume: 82 Topics: Alcohol Drinking; Amino Acid Transport System X-AG; Animals; Cocaine; Ethanol; Glutamic Acid; Male; Neuroglia; Nucleus Accumbens; Prefrontal Cortex; Rats; Substance Withdrawal Syndrome	2017
Reduced Levels of mGlu2 Receptors within the Prelimbic Cortex Are Not Associated with Elevated Glutamate Transmission or High Alcohol Drinking. Alcoholism, clinical and experimental research, 2017, Volume: 41, Issue:11 Topics: Alcohol Drinking; Animals; Cerebral Cortex; Ethanol; Female; Glutamic Acid; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synaptic Transmission	2017
A role for nucleus accumbens glutamate in the expression but not the induction of behavioural sensitization to ethanol. Behavioural brain research, 2018, 01-15, Volume: 336 Topics: Alcohol Drinking; Animals; Behavior, Animal; Ethanol; Glutamic Acid; Learning; Male; Mice; Mice, Inbred DBA; Motor Activity; Nucleus Accumbens; Receptors, N-Methyl-D-Aspartate	2018
Effects of Alcohol Cues on MRS Glutamate Levels in the Anterior Cingulate. Alcohol and alcoholism (Oxford, Oxfordshire), 2018, May-01, Volume: 53, Issue:3 Topics: Adult; Alcohol Drinking; Alcoholism; Cues; Female; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Photic Stimulation; Young Adult	2018
Alcohol and substance use are associated with altered metabolome in the first trimester serum samples of pregnant mothers. European journal of obstetrics, gynecology, and reproductive biology, 2018, Volume: 223 Topics: Adult; Alcohol Drinking; Birth Weight; Female; Glutamic Acid; Glutamine; Humans; Mass Spectrometry; Metabolome; Mothers; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Serotonin; Smoking; Substance-Related Disorders	2018
Effects of Ethanol Exposure on the Neurochemical Profile of a Transgenic Mouse Model with Enhanced Glutamate Release Using In Vivo Neurochemical research, 2019, Volume: 44, Issue:1 Topics: Alcohol Drinking; Animals; Brain; Disease Models, Animal; Ethanol; Glutamate Dehydrogenase; Glutamic Acid; Mice; Mice, Inbred C57BL; Mice, Transgenic; Proton Magnetic Resonance Spectroscopy; Receptors, Glutamate	2019
Brain Glutamate, GABA, and Glutamine Levels and Associations with Recent Drinking in Treatment-Naïve Individuals with Alcohol Use Disorder Versus Light Drinkers. Alcoholism, clinical and experimental research, 2019, Volume: 43, Issue:2 Topics: Adult; Alcohol Drinking; Alcoholism; Aspartic Acid; Case-Control Studies; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Male; Proton Magnetic Resonance Spectroscopy; Young Adult	2019
Loss of control of alcohol use and severity of alcohol dependence in non-treatment-seeking heavy drinkers are related to lower glutamate in frontal white matter. Alcoholism, clinical and experimental research, 2013, Volume: 37, Issue:10 Topics: Adult; Alcohol Drinking; Alcoholism; Biomarkers; Diagnostic and Statistical Manual of Mental Disorders; Female; Frontal Lobe; Glutamic Acid; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Fibers, Myelinated; Severity of Illness Index	2013
Repeated binge-like ethanol drinking alters ethanol drinking patterns and depresses striatal GABAergic transmission. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014, Volume: 39, Issue:3 Topics: Alcohol Drinking; Analysis of Variance; Animals; Central Nervous System Depressants; Choice Behavior; Circadian Rhythm; Corpus Striatum; Ethanol; GABA Antagonists; GABAergic Neurons; Glutamic Acid; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neurons; Picrotoxin; Synaptic Transmission; Time Factors	2014
Acamprosate {monocalcium bis(3-acetamidopropane-1-sulfonate)} reduces ethanol-drinking behavior in rats and glutamate-induced toxicity in ethanol-exposed primary rat cortical neuronal cultures. European journal of pharmacology, 2013, Oct-15, Volume: 718, Issue:1-3 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acamprosate; Alcohol Drinking; Animals; Behavior, Animal; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Ethanol; Glutamic Acid; Lactate Dehydrogenases; Male; Neurons; Neuroprotective Agents; Neurotoxins; Nifedipine; Pyridines; Rats; Rats, Wistar; Signal Transduction; Taurine	2013
Increased extracellular glutamate in the nucleus accumbens promotes excessive ethanol drinking in ethanol dependent mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014, Volume: 39, Issue:3 Topics: Alcohol Drinking; Alcoholism; Amino Acids; Analysis of Variance; Animals; Aspartic Acid; Bridged Bicyclo Compounds, Heterocyclic; Excitatory Amino Acid Agents; Extracellular Fluid; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Microdialysis; Microinjections; Nucleus Accumbens	2014
Loss of metabotropic glutamate receptor 2 escalates alcohol consumption. Proceedings of the National Academy of Sciences of the United States of America, 2013, Oct-15, Volume: 110, Issue:42 Topics: Alcohol Drinking; Animals; Codon, Terminator; Crosses, Genetic; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Glutamic Acid; Mice; Mice, Knockout; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synapses; Synaptic Transmission	2013
Exploring the role of central astrocytic glutamate uptake in ethanol reward in mice. Alcoholism, clinical and experimental research, 2014, Volume: 38, Issue:5 Topics: Alcohol Drinking; Amino Acid Transport System X-AG; Animals; Astrocytes; Ethanol; Glutamic Acid; Infusions, Intraventricular; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Reward	2014
Effects of ceftriaxone on ethanol intake: a possible role for xCT and GLT-1 isoforms modulation of glutamate levels in P rats. Psychopharmacology, 2014, Volume: 231, Issue:20 Topics: Alcohol Drinking; Alcoholism; Amino Acid Transport Systems, Acidic; Animals; Ceftriaxone; Ethanol; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamic Acid; Male; Nucleus Accumbens; Prefrontal Cortex; Protein Isoforms; Rats; Up-Regulation	2014
Evaluation of guanfacine as a potential medication for alcohol use disorder in long-term drinking rats: behavioral and electrophysiological findings. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015, Mar-13, Volume: 40, Issue:5 Topics: Alcohol Deterrents; Alcohol Drinking; Alcohol-Related Disorders; Animals; Central Nervous System Depressants; Choice Behavior; Conditioning, Operant; Disease Models, Animal; Drug Evaluation, Preclinical; Drug-Seeking Behavior; Ethanol; Glutamic Acid; Guanfacine; Male; Naltrexone; Prefrontal Cortex; Pyramidal Cells; Rats, Wistar; Tissue Culture Techniques; Treatment Outcome	2015
Potential dual role of cephalosporins in management of alcohol use disorders. Psychopharmacology, 2014, Volume: 231, Issue:24 Topics: Alcohol Drinking; Amino Acid Transport Systems, Acidic; Animals; Ceftriaxone; Ethanol; Glutamic Acid; Male; Nucleus Accumbens; Prefrontal Cortex	2014
Moderate Alcohol Drinking and the Amygdala Proteome: Identification and Validation of Calcium/Calmodulin Dependent Kinase II and AMPA Receptor Activity as Novel Molecular Mechanisms of the Positive Reinforcing Effects of Alcohol. Biological psychiatry, 2016, Mar-15, Volume: 79, Issue:6 Topics: Alcohol Drinking; Amygdala; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Ethanol; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Phosphorylation; Proteome; Receptors, AMPA; Signal Transduction	2016
Postnatal administration of allopregnanolone modifies glutamate release but not BDNF content in striatum samples of rats prenatally exposed to ethanol. BioMed research international, 2015, Volume: 2015 Topics: Alcohol Drinking; Animals; Brain-Derived Neurotrophic Factor; Corpus Striatum; Ethanol; Female; Glutamic Acid; Male; Pregnancy; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A	2015
Ceftriaxone attenuates ethanol drinking and restores extracellular glutamate concentration through normalization of GLT-1 in nucleus accumbens of male alcohol-preferring rats. Neuropharmacology, 2015, Volume: 97 Topics: Alcohol Deterrents; Alcohol Drinking; Alcoholism; Animals; Ceftriaxone; Central Nervous System Depressants; Disease Models, Animal; Ethanol; Excitatory Amino Acid Transporter 2; Extracellular Space; Glutamate-Ammonia Ligase; Glutamic Acid; Kainic Acid; Male; Microdialysis; Nucleus Accumbens; Rats	2015
Chronic postnatal stress induces voluntary alcohol intake and modifies glutamate transporters in adolescent rats. Stress (Amsterdam, Netherlands), 2015, Volume: 18, Issue:4 Topics: Alcohol Drinking; Animals; Brain; Central Nervous System Depressants; Chronic Disease; Cold Temperature; Ethanol; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Frontal Lobe; Glutamic Acid; Hippocampus; Male; Maternal Deprivation; Rats; Rats, Wistar; Self Administration; Stress, Psychological	2015
Hippocampal glutamate is increased and associated with risky drinking in young adults with major depression. Journal of affective disorders, 2015, Nov-01, Volume: 186 Topics: Alcohol Drinking; Case-Control Studies; Depressive Disorder, Major; Female; Glutamic Acid; Hippocampus; Humans; Male; Proton Magnetic Resonance Spectroscopy; Risk-Taking; Young Adult	2015
Co-administration of ethanol and nicotine: the enduring alterations in the rewarding properties of nicotine and glutamate activity within the mesocorticolimbic system of female alcohol-preferring (P) rats. Psychopharmacology, 2015, Volume: 232, Issue:23 Topics: Alcohol Drinking; Alcoholism; Animals; Drug Combinations; Ethanol; Female; Glutamic Acid; Limbic System; Nicotine; Nucleus Accumbens; Rats; Reward; Self Administration	2015
Glutamatergic transmission in the central nucleus of the amygdala is selectively altered in Marchigian Sardinian alcohol-preferring rats: Alcohol and CRF effects. Neuropharmacology, 2016, Volume: 102 Topics: Alcohol Drinking; Animals; Central Amygdaloid Nucleus; Ethanol; Excitatory Postsynaptic Potentials; Glutamic Acid; Neurons; Pyrimidines; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone	2016
Chronic pain causes a persistent anxiety state leading to increased ethanol intake in CD1 mice. Journal of psychopharmacology (Oxford, England), 2016, Volume: 30, Issue:2 Topics: Alcohol Drinking; Animals; Anxiety; Behavior, Animal; Brain-Derived Neurotrophic Factor; Chronic Pain; Depression; Disease Models, Animal; Ethanol; Glutamic Acid; Hyperalgesia; Interleukin-6; Male; Mice; Prefrontal Cortex; Serotonin; Time Factors	2016
Both genetic deletion and pharmacological blockade of lysophosphatidic acid LPA1 receptor results in increased alcohol consumption. Neuropharmacology, 2016, Volume: 103 Topics: Alcohol Drinking; Animals; Anxiety; Cannabinoids; Ethanol; Female; Glutamic Acid; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Prefrontal Cortex; Propionates; Rats; Rats, Wistar; Receptors, Lysophosphatidic Acid; Reflex, Righting; Sleep	2016
Binge ethanol withdrawal: Effects on post-withdrawal ethanol intake, glutamate-glutamine cycle and monoamine tissue content in P rat model. Behavioural brain research, 2016, Apr-15, Volume: 303 Topics: Alcohol Drinking; Amino Acid Transport Systems, Acidic; Animals; Biogenic Monoamines; Disease Models, Animal; Dopamine; Ethanol; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Male; Nucleus Accumbens; Prefrontal Cortex; Rats; Serotonin; Substance Withdrawal Syndrome	2016
Associations Between Recent Heavy Drinking and Dorsal Anterior Cingulate N-Acetylaspartate and Glutamate Concentrations in Non-Treatment-Seeking Individuals with Alcohol Dependence. Alcoholism, clinical and experimental research, 2016, Volume: 40, Issue:3 Topics: Adult; Alcohol Drinking; Alcoholism; Aspartic Acid; Biomarkers; Female; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Young Adult	2016
Brain metabolite levels in recently sober individuals with alcohol use disorder: Relation to drinking variables and relapse. Psychiatry research. Neuroimaging, 2016, Apr-30, Volume: 250 Topics: Adult; Alcohol Abstinence; Alcohol Drinking; Alcoholism; Aspartic Acid; Brain; Choline; Chronic Disease; Creatine; Female; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Recurrence	2016
Alcohol consumption increases basal extracellular glutamate in the nucleus accumbens core of Sprague-Dawley rats without increasing spontaneous glutamate release. The European journal of neuroscience, 2016, Volume: 44, Issue:2 Topics: Alcohol Drinking; Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Excitatory Amino Acid Transporter 2; Excitatory Postsynaptic Potentials; Exocytosis; Glutamic Acid; Male; Miniature Postsynaptic Potentials; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Sodium Channel Blockers; Tetrodotoxin	2016
Reduced glutamate in white matter of male neonates exposed to alcohol in utero: a (1)H-magnetic resonance spectroscopy study. Metabolic brain disease, 2016, Volume: 31, Issue:5 Topics: Alcohol Drinking; Cohort Studies; Female; Glutamic Acid; Humans; Infant, Newborn; Magnetic Resonance Spectroscopy; Male; Pregnancy; Prenatal Exposure Delayed Effects; Protons; Sex Characteristics; White Matter	2016
Elevated Glutamate Levels in the Left Dorsolateral Prefrontal Cortex Are Associated with Higher Cravings for Alcohol. Alcoholism, clinical and experimental research, 2016, Volume: 40, Issue:8 Topics: Adult; Alcohol Abstinence; Alcohol Drinking; Alcohol-Related Disorders; Craving; Female; Glutamic Acid; Humans; Longitudinal Studies; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Substance Abuse Treatment Centers	2016
Could ethanol-induced alterations in the expression of glutamate transporters in testes contribute to the effect of paternal drinking on the risk of abnormalities in the offspring? Medical hypotheses, 2017, Volume: 98 Topics: Alcohol Drinking; Alcoholism; Amino Acid Transport System X-AG; Animals; Biological Transport; Brain; Congenital Abnormalities; Ethanol; Excitatory Amino Acid Transporter 1; Fathers; Female; Glutamic Acid; Glutamine; Humans; Male; Mice; Models, Biological; Paternal Exposure; Risk; Signal Transduction; Testis	2017
Accumbens Homer2-mediated signaling: a factor contributing to mouse strain differences in alcohol drinking? Genes, brain, and behavior, 2011, Volume: 10, Issue:1 Topics: Alcohol Drinking; Animals; Blotting, Western; Carrier Proteins; Chromatography, High Pressure Liquid; Corpus Striatum; Dependovirus; Genetic Vectors; Glutamic Acid; Homer Scaffolding Proteins; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microdialysis; Nerve Tissue Proteins; Nucleus Accumbens; Phenotype; Polymorphism, Genetic; Signal Transduction; Species Specificity	2011
Alcohol-seeking behavior is associated with increased glutamate transmission in basolateral amygdala and nucleus accumbens as measured by glutamate-oxidase-coated biosensors. Addiction biology, 2011, Volume: 16, Issue:2 Topics: Alcohol Drinking; Alcoholism; Amino Acid Oxidoreductases; Amygdala; Animals; Biosensing Techniques; Brain Mapping; Cues; Extinction, Psychological; Glutamic Acid; Male; Motivation; Nucleus Accumbens; Rats; Rats, Wistar; Self Administration; Synaptic Transmission	2011
Acamprosate reduces ethanol drinking behaviors and alters the metabolite profile in mice lacking ENT1. Neuroscience letters, 2011, Feb-25, Volume: 490, Issue:2 Topics: Acamprosate; Alcohol Drinking; Animals; Equilibrative Nucleoside Transporter 1; Ethanol; Glutamic Acid; Male; Metabolome; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Nucleus Accumbens; Taurine; Up-Regulation	2011
Repeated exposure to moderate doses of ethanol augments hippocampal glutamate neurotransmission by increasing release. Addiction biology, 2011, Volume: 16, Issue:2 Topics: Alcohol Drinking; Animals; Brain Mapping; CA3 Region, Hippocampal; Ethanol; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Microdialysis; Rats; Rats, Wistar; Synaptic Transmission	2011
Type 1 equilibrative nucleoside transporter regulates ethanol drinking through accumbal N-methyl-D-aspartate receptor signaling. Biological psychiatry, 2011, Jun-01, Volume: 69, Issue:11 Topics: 2-Amino-5-phosphonovalerate; Alcohol Drinking; Analysis of Variance; Animals; Blotting, Western; Cyclic AMP Response Element-Binding Protein; Equilibrative Nucleoside Transporter 1; Ethanol; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Mice; Mice, Knockout; Microdialysis; Nucleus Accumbens; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Self Administration; Signal Transduction	2011
Behavioral and neurotransmitter specific roles for the ventral tegmental area in reinforcer-seeking and intake. Alcoholism, clinical and experimental research, 2012, Volume: 36, Issue:10 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alcohol Drinking; Animals; Behavior, Addictive; Dopamine; Ethanol; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microinjections; Rats; Rats, Long-Evans; Reinforcement, Psychology; Ventral Tegmental Area	2012
Timing-dependent reduction in ethanol sedation and drinking preference by NMDA receptor co-agonist d-serine. Alcohol (Fayetteville, N.Y.), 2012, Volume: 46, Issue:4 Topics: Alcohol Drinking; Alcoholic Intoxication; Analysis of Variance; Animals; Ethanol; Glutamic Acid; Glycine; Male; Mice; Motor Activity; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Serine; Time Factors	2012
Glutamatergic input to the lateral hypothalamus stimulates ethanol intake: role of orexin and melanin-concentrating hormone. Alcoholism, clinical and experimental research, 2013, Volume: 37, Issue:1 Topics: Alcohol Drinking; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glutamic Acid; Hypothalamic Area, Lateral; Hypothalamic Hormones; Intracellular Signaling Peptides and Proteins; Male; Melanins; N-Methylaspartate; Neuropeptides; Orexins; Pituitary Hormones; Rats; Rats, Sprague-Dawley	2013
Maternal separation and proclivity for ethanol intake: a potential role of the endocannabinoid system in rats. Neuroscience, 2012, Oct-25, Volume: 223 Topics: Age Factors; Alcohol Drinking; Analysis of Variance; Animals; Animals, Newborn; Brain; Central Nervous System Depressants; Endocannabinoids; Ethanol; Female; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Glutamic Acid; Male; Maternal Deprivation; Methyl-CpG-Binding Protein 2; Pregnancy; Rats; Rats, Wistar; Receptors, Cannabinoid	2012
Effects of NMDA glutamate receptor antagonist drugs on the volitional consumption of ethanol by a genetic drinking rat. Brain research bulletin, 2004, Sep-30, Volume: 64, Issue:3 Topics: Alcohol Drinking; Alcohol-Induced Disorders, Nervous System; Alcoholism; Amino Acids, Cyclic; Animals; Brain; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ethanol; Excitatory Amino Acid Antagonists; Female; Genetic Predisposition to Disease; Glutamic Acid; Isoquinolines; Male; Motor Activity; Pyrrolidinones; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Volition	2004
The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption. Nature medicine, 2005, Volume: 11, Issue:1 Topics: Acamprosate; Alcohol Deterrents; Alcohol Drinking; Alcoholism; Amino Acid Transport System X-AG; Animals; Biological Clocks; Cell Cycle Proteins; Cocaine; Cocaine-Related Disorders; Glutamic Acid; Humans; Mice; Nuclear Proteins; Period Circadian Proteins; Taurine; Time Factors; Transcription Factors	2005
Clock reset for alcoholism. Nature medicine, 2005, Volume: 11, Issue:1 Topics: Alcohol Drinking; Alcoholism; Animals; Biological Clocks; Cell Cycle Proteins; Cocaine; Cocaine-Related Disorders; Glutamic Acid; Humans; Mice; Nuclear Proteins; Period Circadian Proteins; Transcription Factors	2005
The metabotropic glutamate 5 receptor antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]-pyridine reduces ethanol self-administration in multiple strains of alcohol-preferring rats and regulates olfactory glutamatergic systems. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:2 Topics: Alcohol Drinking; Alcoholism; Animals; Autoradiography; Biomarkers; Brain Chemistry; Conditioning, Operant; Depression; Drinking; Glutamic Acid; In Situ Hybridization; Male; Motor Activity; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Smell; Swimming; Thiazoles	2005
Extracellular glutamate and GABA in the ventral tegmental area of alcohol-preferring AA and alcohol-avoiding ANA rats treated repeatedly with morphine. European journal of pharmacology, 2007, Mar-15, Volume: 559, Issue:1 Topics: Alcohol Drinking; Analgesics, Opioid; Animals; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Indicators and Reagents; Male; Microdialysis; Morphine; Motor Activity; Rats; Ventral Tegmental Area	2007
Accumbens neurochemical adaptations produced by binge-like alcohol consumption. Psychopharmacology, 2007, Volume: 190, Issue:4 Topics: Alcohol Drinking; Alcoholism; Animals; Central Nervous System Depressants; Disease Models, Animal; Dopamine; Ethanol; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Microdialysis; Nucleus Accumbens; Reproducibility of Results; Serotonin; Time Factors	2007
Combined antagonism of glutamate mGlu5 and adenosine A2A receptors interact to regulate alcohol-seeking in rats. The international journal of neuropsychopharmacology, 2008, Volume: 11, Issue:2 Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Alcohol Drinking; Animals; Behavior, Animal; Central Nervous System Depressants; Conditioning, Operant; Cues; Dose-Response Relationship, Drug; Ethanol; Extinction, Psychological; Glutamic Acid; Models, Animal; Motor Activity; Pyridines; Pyrimidines; Rats; Rats, Inbred Strains; Reaction Time; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Self Administration; Thiazoles; Time Factors; Triazoles; Xanthines	2008
Alcohol preference in mice lacking the Avpr1a vasopressin receptor. American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 294, Issue:5 Topics: Alcohol Drinking; Amino Acids; Animals; Arginine Vasopressin; Central Nervous System Depressants; Dizocilpine Maleate; Ethanol; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; In Situ Hybridization; Mice; Mice, Inbred C57BL; Mice, Knockout; Naltrexone; Narcotic Antagonists; Receptors, N-Methyl-D-Aspartate; Receptors, Vasopressin; Sex Characteristics	2008
Strain differences in alcohol-induced neurochemical plasticity: a role for accumbens glutamate in alcohol intake. Alcoholism, clinical and experimental research, 2008, Volume: 32, Issue:4 Topics: Alcohol Drinking; Animals; Ethanol; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microdialysis; Neuronal Plasticity; Nucleus Accumbens; Species Specificity	2008
[Effect of ethanol on the neurotransmitters glutamate and GABA]. Archiv fur Psychiatrie und Nervenkrankheiten, 1982, Volume: 232, Issue:2 Topics: Alcohol Drinking; Animals; Brain; Corpus Striatum; Frontal Lobe; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Male; Muridae; Substantia Nigra	1982
Regional effects of ethanol on glutamate levels, uptake and release in slice and synaptosome preparations from rat brain. Substance and alcohol actions/misuse, 1983, Volume: 4, Issue:6 Topics: Alcohol Drinking; Alcohol Withdrawal Delirium; Alcoholism; Animals; Corpus Striatum; Culture Techniques; Ethanol; Frontal Lobe; Glutamates; Glutamic Acid; Hippocampus; Humans; Male; Rats; Rats, Inbred Strains; Synaptic Transmission; Synaptosomes	1983
Glutamine-induced alterations in the content of brain amino acid neurotransmitters in rats with different alcohol motivation. Substance and alcohol actions/misuse, 1984, Volume: 5, Issue:5 Topics: Alcohol Drinking; Amino Acids; Animals; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Motivation; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Taurine	1984
Ethanol sensitivity of brain NMDA receptors in mice selectively bred for differences in response to the low-dose locomotor stimulant effects of ethanol. Alcoholism, clinical and experimental research, 1994, Volume: 18, Issue:6 Topics: Alcohol Drinking; Animals; Brain; Calcium; Dose-Response Relationship, Drug; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred Strains; Motor Activity; Receptors, N-Methyl-D-Aspartate; Selection, Genetic; Stimulation, Chemical	1994
Effects of in vitro ethanol and chronic ethanol consumption on the release of excitatory amino acids in the rat hippocampus. Brain research, 1995, Mar-13, Volume: 674, Issue:1 Topics: Alcohol Drinking; Animals; Aspartic Acid; Ethanol; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Time Factors	1995
Effect of ethanol on extracellular 5-HT and glutamate in the nucleus accumbens and prefrontal cortex: comparison between the Lewis and Fischer 344 rat strains. Brain research, 1996, Apr-15, Volume: 716, Issue:1-2 Topics: Alcohol Drinking; Animals; Central Nervous System Depressants; Ethanol; Extracellular Space; Glutamic Acid; Injections, Intraperitoneal; Male; Microdialysis; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Inbred F344; Rats, Inbred Lew; Serotonin; Species Specificity	1996
Dose-dependent effects of acute in vivo ethanol exposure on extracellular glutamate concentration in the cerebral cortex of the near-term fetal sheep. Alcoholism, clinical and experimental research, 1995, Volume: 19, Issue:6 Topics: Alcohol Drinking; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Ethanol; Extracellular Space; Female; Fetal Alcohol Spectrum Disorders; Gestational Age; Glutamic Acid; Humans; Infant, Newborn; Microdialysis; Neurons; Pregnancy; Sheep	1995
Structure of mitochondrial aldehyde dehydrogenase: the genetic component of ethanol aversion. Structure (London, England : 1993), 1997, May-15, Volume: 5, Issue:5 Topics: Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Binding Sites; Cattle; Crystallography, X-Ray; Enzyme Stability; Glutamic Acid; Mitochondria; Models, Molecular; Molecular Sequence Data; NAD; Protein Conformation	1997
Taurine and ethanol preference: a microdialysis study using Sardinian alcohol-preferring and non-preferring rats. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2000, Volume: 10, Issue:5 Topics: Alanine; Alcohol Drinking; Animals; Arginine; Chromatography, High Pressure Liquid; Conditioning, Psychological; Ethanol; Glutamic Acid; Kinetics; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Inbred Strains; Species Specificity; Taurine; Time Factors	2000