glutamic acid and Akinetic-Rigid Variant of Huntington Disease

glutamic acid has been researched along with Akinetic-Rigid Variant of Huntington Disease in 155 studies

Research

Studies (155)

Timeframe	Studies, this research(%)	All Research%
pre-1990	16 (10.32)	18.7374
1990's	22 (14.19)	18.2507
2000's	52 (33.55)	29.6817
2010's	55 (35.48)	24.3611
2020's	10 (6.45)	2.80

Authors

Authors	Studies
Brouillet, E; Célestine, M; Dhenain, M; Flament, J; Humbert, S; Palombo, M; Pérot, JB	1
Alvarez, R; Baldassarro, VA; Charles, AL; Ciancia, M; de Lera, AR; Dollé, P; Fraulob, V; Geny, B; Krężel, W; Muramatsu, SI; Niewiadomska-Cimicka, A; Rataj-Baniowska, M; Zinter, N	1
Buren, C; Fung, E; Hayden, MR; Koch, ET; Mackay, JP; Nassrallah, WB; Raymond, LA; Schmidt, M; Smith-Dijak, AI; Zhang, P	1
Dvorzhak, A; Grantyn, R	1
Bakels, R; Barazzuol, L; Bergink, S; Boddeke, EHWG; Brunsting, JF; Cattaneo, E; Conforti, P; Copray, S; de Mattos, EP; Fatima, A; Kampinga, HH; Koyuncu, S; Serlidaki, D; Thiruvalluvan, A; Vilchez, D	1
Buren, C; Raymond, LA; Tu, G	1
Alberch, J; Artigas, F; Bernal-Casas, D; Campa, L; Conde-Berriozabal, S; Fernández-García, S; García-Díaz Barriga, G; García-García, E; Gort-Paniello, C; López-Gil, J; Masana, M; Muñoz-Moreno, E; Rodríguez, MJ; Soria, G	1
Cepeda, C; Levine, MS	1
Diniz, DM; Fernandes, LF; Gomez, MV; Guatimosim, C; Joviano-Santos, JV; Ladeira, MS; Machado, TCG; Magalhães-Gomes, MPS; Massensini, AR; Miranda, AS; Soares, KB; Valadão, PAC	1
Aldana, BI; Andersen, JV; Jakobsen, E; Markussen, KH; Rosenberg, PA; Schousboe, A; Waagepetersen, HS	1
Cepeda, C; Kamdjou, T; Levine, MS; Meshul, CK; Moore, C; Parievsky, A	1
Alpaugh, M; Baker, GB; Di Pardo, A; Forero, J; Fouad, K; Galleguillos, D; Holt, A; Kar, P; Kerr, BJ; Lackey, SW; Morales, LC; Sipione, S; Todd, KG	1
Bajo-Grañeras, R; Bellocchio, L; Chiarlone, A; Ferrero, JJ; Galve-Roperh, I; Gaudioso, Á; Guzmán, M; Maroto, IB; Marsicano, G; Resel, E; Rodríguez-Navarro, JA; Ruiz-Calvo, A; Sánchez-Prieto, J	1
Rebec, GV	2
Jamwal, S; Kumar, P	1
Aldana, BI; Andersen, JV; Nielsen, ML; Nørremølle, A; Santos, A; Skotte, NH; Waagepetersen, HS; Willert, CW	1
Flament, J; Hantraye, P; Valette, J	1
Koch, ET; Raymond, LA; Woodard, CL	1
Koch, ET; Raymond, LA	1
Aoki, C; Dubinsky, JM; Hussey, KC; Petr, GT; Rosenberg, PA; Schultheis, LA; Sun, Y	1
Gottipati, MK; Gray, M; Lee, W; Lesort, M; Lewis, K; Parpura, V; Reyes, RC	1
Gaertig, MA; Huang, S; Li, H; Li, S; Li, XJ; Liu, X; Song, M; Wang, CE; Xu, Q; Yan, S; Yu, SP	1
Chakraborty, J; Mohanakumar, KP; Rajamma, U	1
Aylward, EH; Conley, KE; Laurino, MY; Padowski, JM; Richards, TL; Samii, A; Weaver, KE	1
Raymond, LA; Sepers, MD	1
Ansong, KA; Aronin, N; DiFiglia, M; Green, KM; Kegel, KB; Kimm, JS; Kwak, S; McClory, H; Sapp, E; Shaffer, SA; Valencia, A; Yohrling, G	1
Cregan, SP; Doria, JG; Ferguson, SS; Guimaraes, IM; Hamilton, A; Ribeiro, FM	1
Beggiato, S; Ferrante, A; Ferraro, L; Martire, A; Pepponi, R; Popoli, P; Tebano, MT; Varani, K; Vincenzi, F	1
Andrade, JN; Carvalho, TG; de Souza, JM; Dobransky, T; Doria, JG; Guatimosim, C; Guimaraes, IM; Ribeiro, FM; Rodrigues, HA	1
Fang, Y; Fung, CK; Iu, CY; Lai, KW; Li, HW; Lui, CN; Xi, N; Yung, KK; Zou, Y	1
Altemus, M; Sandstrom, MI; Wickwire, JH; Wolfram-Aduan, A	1
Akimov, S; Arjomand, J; Doty, CN; Hayden, MR; Lenaeus, L; Mandefro, B; Mattis, VB; Ornelas, L; Ross, CA; Saeedian, J; Sahabian, A; Sareen, D; Southwell, AL; Svendsen, CN; Tom, C; Østergaard, ME	1
Tang, TS; Wang, JQ; Wang, QC; Wang, Y; Xie, W; Yao, S	1
Bichell, TJ; Bowman, AB; Bradley, E; Bridges, TM; Conn, PJ; Daniels, JS; Foster, DJ; Jones, CK; Klar, R; Lindsley, CW; Moehle, MS; Niswender, CM; Pancani, T; Poslusney, M; Rook, JM; Wood, MR; Xiang, Z	1
Cabiscol, E; Fernández-Nogales, M; Ferrer, I; Lucas, JJ; Rodríguez-Colman, MJ; Sorolla, MA; Vall-Llaura, N; Vived, C	1
Buren, C; Parsons, MP; Raymond, LA; Smith-Dijak, A	1
Kumar, P; Singh, S	1
Diaz-Castro, B; Jiang, R; Khakh, BS; Looger, LL	1
Kang, R; Murphy, TH; Parsons, MP; Raymond, LA; Vanni, MP; Woodard, CL	1
Mahfooz, K; Marco, S; Martínez-Turrillas, R; Pérez-Otaño, I; Raja, MK; Wesseling, JF	1
Dvorzhak, A; Grantyn, R; Kirmse, K; Vagner, T	1
Brouillet, E; Cambon, K; Carrillo-de Sauvage, MA; de Longprez, L; Flament, J; Francelle, L; Gipchtein, P; Pépin, J; Valette, J	1
Déglon, N; Jollé, C; Merienne, N; Meunier, C; Pellerin, L	1
Morton, AJ; Sawiak, SJ; Wood, NI	1
Deshmukh, R; Gill, JS; Jamwal, S; Kumar, P	1
Banaie, M; Gharibzadeh, S; Sarbaz, Y; Towhidkhah, F	2
Joseph, SA; Mark, LP; Prost, RW; Reynolds, NC	1
Estrada-Sánchez, AM; Massieu, L; Montiel, T; Segovia, J	1
Bezprozvanny, I; Bulin, SE; Jeong, HK; Kwon, SW; Park, JH; Wu, J	1
Dong, XX; Qin, ZH; Wang, Y	1
Beesen, AA; Déglon, N; Gokce, O; Kaneko, YA; Luthi-Carter, R; Régulier, E; Rudinskiy, N	1
Bradford, J; Li, S; Li, XJ; Roberts, M; Shin, JY; Wang, CE	1
Bradford, J; Li, S; Li, XJ; Roberts, M; Sheng, G; Shin, JY; Wang, CE	1
Estrada-Sánchez, AM; Massieu, L; Montiel, T	1
André, VM; Cepeda, C; Levine, MS	1
Auregan, G; Bonvento, G; Brouillet, E; Cormier, K; Déglon, N; Dufour, N; Faideau, M; Ferrante, RJ; Gilmore, R; Guillermier, M; Hantraye, P; Kim, J; Welch, M	1
Agbas, A; Bao, X; Michaelis, EK; Pal, R; Wang, X	1
Bertoncini, CR; Fernandes, MJ; Hirata, H; Rosenstock, TR; Smaili, SS; Teles, AV	1
Askew, C; Davis, NG; Hayden, MR; Huang, K; Kang, MH; Kang, R; Sanders, SS; Wan, J	1
Ferguson, SS; Pires, RG; Ribeiro, FM	1
Cormier, K; Del Signore, SJ; Kosaras, B; Kowall, NW; Lee, J; McKee, A; Ratan, RR; Ryu, H	1
André, VM; Bardakjian, N; Cepeda, C; Fisher, YE; Huynh, M; Levine, MS; Singh, S; Yang, XW	1
Ahlijanian, M; Bezprozvanny, I; Chen, X; Chesworth, R; Diggins, L; Glushankova, L; Hrdlicka, L; Kaznacheyeva, E; Koenig, G; Mahoney, M; Mozhayeva, GN; Shapiro, G; Shih, HP; Singh, C; Vigont, V; Wu, J; Wu, Q; Zimina, O	1
Bincoletto, C; Carvalho, JT; Hirata, H; Lopes, GS; Oseki, KT; Rocha, KK; Rodrigues, L; Smaili, SS; Ureshino, RP	1
Bezprozvanny, I; Chen, X; Herndon, E; Lvovskaya, S; Supnet, C; Wu, J	1
Goto, S; Kaji, R; Koizumi, H; Morigaki, R; Nagahiro, S; Okita, S	1
Bodai, L; Marsh, JL	1
Alexander, R; Kanes, S; Lee, CM; McCarthy, DJ; Pathak, S; Sanacora, G; Smith, MA	1
Barker, PB; Bassett, SS; Brandt, J; Carass, A; Edden, RA; Liu, X; Margolis, RL; Oishi, K; Redgrave, GW; Ross, CA; Shanahan, M; Unschuld, PG; van Zijl, PC; Wang, X	1
Eddy, C; Mittal, SK	1
Beaumont, V; Bradaia, A; Buisson, B; Glaser, JR; Heikkinen, T; Hendricks, SJ; Howland, D; Kontkanen, O; Lehtimäki, K; Munoz-Sanjuan, I; Park, LC; Puoliväli, J; Touller, C; Vartiainen, N; Wadel, K; Yrjänheikki, JM	1
Behrens, PF; Franz, P; Landwehrmeyer, GB; Lindenberg, KS; Woodman, B	1
Bozikov, J; Canki-Klain, N; Hećimović, S; Janko, D; Klepac, N; Marković, D; Pavelić, K; Relja, M; Skarpa-Prpić, I; Vlasić, J; Vojta, A	1
Kosinski, CM; Landwehrmeyer, GB; Lüesse, HG; Milkereit, A; Milkereit, E; Puls, C; Schiefer, J; Sprünken, A	1
Ariano, MA; Calvert, CR; Cepeda, C; Christian, LJ; Hernández-Echeagaray, E; Hurst, RS; Jocoy, E; Levine, MS; Nguyen, OK	1
Bernardini, S; Bonuccelli, U; Del Dotto, P; Dell' Agnello, G; Gambaccini, G; Lucetti, C; Murri, L; Rossi, G	1
Antkiewicz-Michaluk, L; Nalepa, I; Sansone, M; Vetulani, J	1
Bantubungi, K; Blum, D; Brouillet, E; Cuvelier, L; Galas, MC; Gall, D; Galluzzo, M; Ledent, C; Muller, CE; Pintor, A; Popoli, P; Rolland, AS; Schiffmann, SN	1
Corsi, C; Gianfriddo, M; Melani, A; Pedata, F; Pèzzola, A; Popoli, P; Reggio, R	1
Li, H; Li, SH; Li, XJ; Wyman, T; Yu, ZX	1
Beani, L; Bianchi, C; Hanau, S; Marti, M; Mela, F; Morari, M; Paganini, F; Stocchi, S; Ulazzi, L	1
Alda, M; Bauer, M; Priller, J; Young, LT	1
Bernardi, G; Calabresi, P; Centonze, D; Gubellini, P; Gulino, A; Napolitano, M; Rossi, S; Spiezia, S	1
Gianfriddo, M; Giovannini, MG; Melani, A; Pedata, F; Turchi, D	1
Brustovetsky, T; Dubinsky, JM; Purl, K; Shimizu, K; Young, A	1
Mark, LP; Prost, RW; Reynolds, NC	1
Bantubungi, K; Blum, D; Brotchi, J; Brouillet, E; Chtarto, A; Déglon, N; Galas, MC; Greco, A; Jacquard, C; Levivier, M; Minghetti, L; Pintor, A; Popoli, P; Schiffmann, SN; Tai, K; Tenenbaum, L	1
Auer, DP; Bender, A; Bender, J; Dose, M; Gasser, T; Klopstock, T; Merl, T; Reilmann, R; Saemann, P; Weindl, A; Yassouridis, A	1
Birman, S; Chneiweiss, H; Iché, M; Liévens, JC; Rival, T	1
Bezprozvanny, I; Hayden, MR; Kristal, BS; Llinás, R; Lupu, V; Slow, E; Stavrovskaya, IG; Sugimori, M; Tang, TS	1
de Lago, E; Di Marzo, V; Fernández-Ruiz, J; Ramos, JA; Urbani, P	1
Del Mar, N; Deng, YP; Goldowitz, D; Lei, WL; Meade, CA; Reiner, A; Sun, Z; Wang, HB; Xie, JP	1
Baker, D; Cabranes, A; de Lago, E; Fernández-Ruiz, J; López-Rodríguez, M; Ortega-Gutiérrez, S; Pryce, G; Ramos, JA	1
Fang, ZH; Li, SH; Li, XJ; Shin, JY; Wang, CE; Yu, ZX	1
Gogas, KR	1
Chang, DT; Pandipati, S; Reynolds, IJ; Rintoul, GL	1
Di Luca, M; Gardoni, F	1
Brusilow, WS	1
Bezprozvanny, I; Tang, T; Wu, J	1
Bernardi, G; Calabresi, P; Centonze, D; De Chiara, V; Mataluni, G; Picconi, B; Prosperetti, C; Rossi, S	1
Ausserer, H; Bratti, A; Lochner, P; Marth, R; Nardone, R; Tezzon, F	1
Borioni, A; Calamandrei, G; Domenici, MR; Lastoria, G; Martire, A; Popoli, P; Potenza, RL; Scattoni, ML; Venerosi, A	1
Emson, PC; Faull, RL; Hassel, B; Tessler, S	1
Birman, S; Liévens, JC	1
Battaglia, G; Cannella, M; Rampello, L; Riozzi, B; Squitieri, F; Traficante, A	1
Barton, SJ; Dorner, JL; Kennedy, RT; Miller, BR; Rebec, GV; Sari, Y; Sengelaub, DR; Shou, M	1
Gardoni, F	1
Bezprozvanny, I; Graham, RK; Hayden, MR; Li, Q; Slow, E; Zhang, H	1
Arnason, BG; Beutler, BA; Noronha, AB; Poon, MM	1
Mangano, RM; Schwarcz, R	2
Perry, TL	1
McGeer, EG; McGeer, PL; Wong, PT	1
Hornykiewicz, O; Kish, SJ; Perry, TL; Shannak, KS	1
Bernardi, G; Calabresi, P; De Murtas, M; Mercuri, NB; Pisani, A; Sancesario, G; Stefani, A	1
Albin, RL; Kremer, B; Tallaksen-Greene, SJ	1
Beal, MF; Storey, E	1
Lange, HW; Reilmann, R; Rolf, LH	1
Almqvist, E; Andrew, SE; Anvret, M; Goldberg, YP; Goto, J; Kanazawa, I; Nichol, K; Peltonen, L; Spence, N; Vesa, J	1
Dodd, PR; Johnston, GA; Leong, DK	1
Cooper, JM; Gash, MT; Gu, M; Javoy-Agid, F; Mann, VM; Schapira, AH	1
Brooks, DJ; Bryant, DJ; Harding, AE; Marcus, CD; Sargentoni, J; Taylor-Robinson, SD; Weeks, RA	1
Fischer, KM	1
Alsdorf, SA; Bates, GP; Cha, JH; Davies, SW; Kerner, JA; Kosinski, CM; Mangiarini, L; Penney, JB; Young, AB	1
Bernardi, G; Calabresi, P; Centonze, D; Marfia, GA; Marinelli, S; Pisani, A	1
Bates, GP; Dalton, CF; Davies, SW; Mangiarini, L; Reynolds, GP; Tillery, CL	1
Cha, JH; Kosinski, CM; Schwarz, M; Young, AB	1
Baic, C; Higgins, DS; Hoyt, KR; Sulka, M; Vensel, J	1
Gramsbergen, JB; Kornblit, BT; Storgaard, J; Zimmer, J	1
Brotchie, J; Ravenscroft, P	1
Brundin, P; Hansson, O; Haraldsson, B; Nicniocaill, B; O'Connor, WT	1
Deckel, AW	1
Bates, GP; Brundin, P; Castilho, RF; Hansson, O; Korhonen, L; Lindholm, D	1
Bates, GP; Kerkerian-Le Goff, L; Liévens, JC; Mahal, A; Samuel, D; Spasic-Boscovic, O; Woodman, B	1
Domenici, MR; Falchi, M; Frank, C; Malchiodi-Albedi, F; Massotti, M; Pèzzola, A; Pintor, A; Popoli, P; Quarta, D; Reggio, R; Scarchilli, L; Tebano, MT	1
Beal, MF; Finn, SF; Kowall, NW; Mazurek, MF; Storey, E	1
Kuncl, RW; Martin, LJ; Rothstein, JD	1
Beal, MF	1
Chase, TN; Giuffra, ME; Mouradian, MM	1
Aschner, M; Kimelberg, HK	1
Hansen, S; Perry, TL	1
Heathfield, KW; Pearson, SJ; Reynolds, GP	1
Beal, MF; DiFiglia, M; Freese, A; Koroshetz, WJ; Martin, JB	1
Pearson, SJ; Reynolds, GP	1
Meldrum, B	1
D'Amato, CJ; Greenamyre, JT; Hicks, SP; Penney, JB; Shoulson, I; Young, AB	1
Gray, PN; May, PC	2
Cross, AJ; Reynolds, GP; Slater, P	1
Bird, ED; Myers, RH; Schoenfeld, M	1
Choi, DW; Koh, JY; Peters, S	1
Connick, JH; English, M; Hastings, MH; Stone, TW; Winn, P	1
Arrieta, A; Bonilla, E; Prasad, AL	1

Reviews

28 review(s) available for glutamic acid and Akinetic-Rigid Variant of Huntington Disease

Article	Year
Glutamate metabolism and recycling at the excitatory synapse in health and neurodegeneration. Neuropharmacology, 2021, 09-15, Volume: 196 Topics: Alzheimer Disease; Animals; Astrocytes; Energy Metabolism; Glutamic Acid; Homeostasis; Humans; Huntington Disease; Neurodegenerative Diseases; Neurons; Synapses	2021
Corticostriatal network dysfunction in Huntington's disease: Deficits in neural processing, glutamate transport, and ascorbate release. CNS neuroscience & therapeutics, 2018, Volume: 24, Issue:4 Topics: Animals; Ascorbic Acid; Glutamic Acid; Humans; Huntington Disease; Neural Pathways; Neurons	2018
Insight Into the Emerging Role of Striatal Neurotransmitters in the Pathophysiology of Parkinson's Disease and Huntington's Disease: A Review. Current neuropharmacology, 2019, Volume: 17, Issue:2 Topics: Acetylcholine; Adenosine; Animals; Basal Ganglia; Cannabinoids; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Huntington Disease; Neuropeptides; Parkinson Disease; Synaptic Transmission	2019
Dysfunctional striatal dopamine signaling in Huntington's disease. Journal of neuroscience research, 2019, Volume: 97, Issue:12 Topics: Animals; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dopamine; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Neurons; Receptors, Dopamine; Signal Transduction; Substantia Nigra	2019
A mitochondrial basis for Huntington's disease: therapeutic prospects. Molecular and cellular biochemistry, 2014, Volume: 389, Issue:1-2 Topics: Animals; Brain; Cell Death; Glutamic Acid; Humans; Huntington Disease; Mitochondria; Nerve Tissue Proteins	2014
Mechanisms of synaptic dysfunction and excitotoxicity in Huntington's disease. Drug discovery today, 2014, Volume: 19, Issue:7 Topics: Animals; Corpus Striatum; Dopamine; Glutamic Acid; Humans; Huntington Disease; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synapses	2014
Metabotropic glutamate receptor 5 as a potential therapeutic target in Huntington's disease. Expert opinion on therapeutic targets, 2014, Volume: 18, Issue:11 Topics: Animals; Brain; Drug Design; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Molecular Targeted Therapy; Nerve Tissue Proteins; Receptor, Metabotropic Glutamate 5; Signal Transduction	2014
Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases. Acta pharmacologica Sinica, 2009, Volume: 30, Issue:4 Topics: Alzheimer Disease; Animals; Apoptosis; Autophagy; Calcium; Chlorides; Glutamic Acid; Humans; Huntington Disease; Neurodegenerative Diseases; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate	2009
Dopamine and glutamate in Huntington's disease: A balancing act. CNS neuroscience & therapeutics, 2010, Volume: 16, Issue:3 Topics: Animals; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dopamine; Glutamic Acid; Humans; Huntington Disease; Mice; Rats	2010
Huntington's disease and Group I metabotropic glutamate receptors. Molecular neurobiology, 2011, Volume: 43, Issue:1 Topics: Animals; Cannabinoid Receptor Modulators; Cell Survival; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Mutation; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Peptides; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Signal Transduction	2011
The role of mitochondrial function in glutamate-dependent metabolism in neuronal cells. Current pharmaceutical design, 2011, Volume: 17, Issue:35 Topics: Alzheimer Disease; Animals; Autophagy; Calcium Signaling; Energy Metabolism; Excitatory Amino Acid Agents; Glutamic Acid; Humans; Huntington Disease; Mitochondria; Neuroglia; Neuronal Plasticity; Neurons; Neurotoxicity Syndromes; Parkinson Disease; Synaptic Transmission	2011
The role of dopamine and glutamate modulation in Huntington disease. Behavioural neurology, 2013, Volume: 26, Issue:4 Topics: Brain; Dopamine; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Huntington Disease	2013
A possible physiological role for cerebral tetrahydroisoquinolines. Neurotoxicity research, 2003, Volume: 5, Issue:1-2 Topics: Animals; Basal Ganglia Diseases; Glutamic Acid; Humans; Huntington Disease; Memory; Movement; Neostriatum; Neurons; Phosphorylation; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Signal Transduction	2003
Implications of the neuroprotective effects of lithium for the treatment of bipolar and neurodegenerative disorders. Pharmacopsychiatry, 2003, Volume: 36 Suppl 3 Topics: Alzheimer Disease; Bipolar Disorder; Glucocorticoids; Glutamic Acid; Humans; Huntington Disease; Lithium Compounds; Nerve Degeneration; Neurodegenerative Diseases; Neuroprotective Agents; Signal Transduction	2003
Glutamate-based therapeutic approaches: NR2B receptor antagonists. Current opinion in pharmacology, 2006, Volume: 6, Issue:1 Topics: Animals; Brain Ischemia; Clinical Trials as Topic; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Huntington Disease; Pain; Phenols; Piperidines; Protein Conformation; Receptors, N-Methyl-D-Aspartate	2006
New targets for pharmacological intervention in the glutamatergic synapse. European journal of pharmacology, 2006, Sep-01, Volume: 545, Issue:1 Topics: Alzheimer Disease; Animals; Epilepsy; Glutamic Acid; Humans; Huntington Disease; Ischemia; Parkinson Disease; Protein Kinases; Receptors, N-Methyl-D-Aspartate; Synapses	2006
Is Huntington's a glutamine storage disease? The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 2006, Volume: 12, Issue:4 Topics: Animals; Biological Evolution; Brain; Brain Diseases, Metabolic, Inborn; Glutamic Acid; Glutamine; Humans; Huntingtin Protein; Huntington Disease; Nerve Tissue Proteins; Nuclear Proteins; Peptides	2006
[Astrocytes in Huntington's chorea: accomplice or guilty of the neuronal death?]. Medecine sciences : M/S, 2007, Volume: 23, Issue:10 Topics: Animals; Animals, Genetically Modified; Apoptosis; Astrocytes; Drosophila melanogaster; Drosophila Proteins; ErbB Receptors; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Mice; Models, Biological; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Peptides; Rats; Signal Transduction	2007
MAGUK proteins: new targets for pharmacological intervention in the glutamatergic synapse. European journal of pharmacology, 2008, May-06, Volume: 585, Issue:1 Topics: Alzheimer Disease; Animals; Antiparkinson Agents; Chronic Disease; Disks Large Homolog 4 Protein; Dyskinesia, Drug-Induced; Glutamic Acid; Guanylate Kinases; Humans; Huntington Disease; Intracellular Signaling Peptides and Proteins; Levodopa; Membrane Proteins; Pain; Protein Subunits; Receptors, N-Methyl-D-Aspartate; Stroke; Synapses	2008
[Huntington chorea. Animal models reveal new hypotheses for pathophysiology and therapy]. Der Nervenarzt, 1999, Volume: 70, Issue:10 Topics: Animals; Brain; Cell Death; Disease Models, Animal; Glutamic Acid; Humans; Huntington Disease; Mice; Mice, Transgenic; Models, Genetic; Nerve Degeneration; Receptors, Metabotropic Glutamate; Trinucleotide Repeats	1999
NMDA receptors in the basal ganglia. Journal of anatomy, 2000, Volume: 196 ( Pt 4) Topics: Basal Ganglia; Glutamic Acid; Humans; Huntington Disease; Movement Disorders; Parkinson Disease; Receptors, N-Methyl-D-Aspartate	2000
Nitric oxide and nitric oxide synthase in Huntington's disease. Journal of neuroscience research, 2001, Apr-15, Volume: 64, Issue:2 Topics: Animals; Apoptosis; Arginine; Calmodulin; Caspases; Cerebrovascular Circulation; CREB-Binding Protein; Enzyme Activation; Enzyme Induction; Forecasting; Glutamic Acid; Humans; Huntington Disease; Mice; Mice, Transgenic; Mitochondria; Models, Animal; Models, Neurological; Nerve Tissue Proteins; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nuclear Proteins; Oxidative Stress; Proto-Oncogene Proteins p21(ras); RNA, Messenger; Trans-Activators	2001
Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses? Annals of neurology, 1992, Volume: 31, Issue:2 Topics: Aging; Alzheimer Disease; Animals; Brain Diseases; Cell Death; Energy Metabolism; Glutamates; Glutamic Acid; Humans; Huntington Disease; Ion Channel Gating; Mitochondria; Models, Biological; MPTP Poisoning; Nerve Degeneration; Neurons; Neurotoxins; Oxidative Phosphorylation; Parkinson Disease; Parkinson Disease, Secondary; Primates; Rats; Receptors, N-Methyl-D-Aspartate	1992
The use of astrocytes in culture as model systems for evaluating neurotoxic-induced-injury. Neurotoxicology, 1991,Fall, Volume: 12, Issue:3 Topics: Ammonia; Animals; Astrocytes; Cells, Cultured; Glutamates; Glutamic Acid; Huntington Disease; Metals; Models, Neurological; MPTP Poisoning; Nerve Degeneration; Nervous System	1991
What excitotoxin kills striatal neurons in Huntington's disease? Clues from neurochemical studies. Neurology, 1990, Volume: 40, Issue:1 Topics: Adult; Amino Acids; Caudate Nucleus; Glutamates; Glutamic Acid; Humans; Huntington Disease; Middle Aged; Neurotoxins; Putamen	1990
Possible therapeutic applications of antagonists of excitatory amino acid neurotransmitters. Clinical science (London, England : 1979), 1985, Volume: 68, Issue:2 Topics: Alzheimer Disease; Animals; Aspartic Acid; Basal Ganglia Diseases; Brain; Brain Ischemia; Epilepsy; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Humans; Huntington Disease; Mice; Movement Disorders; Nerve Degeneration; Neurotransmitter Agents; Parkinson Disease; Rats	1985
Huntington's disease: genetics, chemical pathology, and management. Progress in medical genetics, 1985, Volume: 6 Topics: Acetylcholine; Age Factors; Brain; Cell Membrane; Chromosomes, Human, 4-5; Diagnosis, Differential; DNA; Dopamine; Family; gamma-Aminobutyric Acid; Genetic Counseling; Glucose; Glutamates; Glutamic Acid; Humans; Huntington Disease; Nerve Tissue Proteins; Polymorphism, Genetic; Serotonin; Sex Factors; Twins	1985
Endogenous excitotoxic agents. Ciba Foundation symposium, 1987, Volume: 126 Topics: Animals; Aspartic Acid; Cell Survival; Central Nervous System; Dementia; Epilepsy; Glutamates; Glutamic Acid; Humans; Huntington Disease; Models, Neurological; Neurons; Quinolinic Acid; Quinolinic Acids	1987

Trials

3 trial(s) available for glutamic acid and Akinetic-Rigid Variant of Huntington Disease

Article	Year
IV amantadine improves chorea in Huntington's disease: an acute randomized, controlled study. Neurology, 2003, Jun-24, Volume: 60, Issue:12 Topics: Administration, Oral; Aged; Amantadine; Cross-Over Studies; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Huntington Disease; Infusions, Intravenous; Male; Middle Aged; Motor Activity; Neuropsychological Tests; Severity of Illness Index; Treatment Outcome	2003
Creatine supplementation lowers brain glutamate levels in Huntington's disease. Journal of neurology, 2005, Volume: 252, Issue:1 Topics: Administration, Oral; Adult; Aspartic Acid; Brain; Cerebral Cortex; Creatine; Down-Regulation; Energy Metabolism; Female; Glutamic Acid; Glutamine; Humans; Huntington Disease; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurologic Examination; Neuroprotective Agents; Pilot Projects; Treatment Outcome	2005
Glutamatergic therapy of Huntington's chorea. Clinical neuropharmacology, 1992, Volume: 15, Issue:2 Topics: Acetamides; Adult; Female; Glutamates; Glutamic Acid; Humans; Huntington Disease; Male; Middle Aged; Monoamine Oxidase Inhibitors; Synaptic Transmission	1992

Other Studies

124 other study(ies) available for glutamic acid and Akinetic-Rigid Variant of Huntington Disease

Article	Year
Longitudinal multimodal MRI characterization of a knock-in mouse model of Huntington's disease reveals early gray and white matter alterations. Human molecular genetics, 2022, 10-28, Volume: 31, Issue:21 Topics: Animals; Brain; Diffusion Tensor Imaging; Disease Models, Animal; Glutamic Acid; Huntington Disease; Magnetic Resonance Imaging; Mice; White Matter	2022
Retinoic acid receptor beta protects striatopallidal medium spiny neurons from mitochondrial dysfunction and neurodegeneration. Progress in neurobiology, 2022, Volume: 212 Topics: Animals; Glutamic Acid; Huntington Disease; Mice; Mitochondria; Neurons; Receptors, Retinoic Acid	2022
Axonal ER Ca The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023, 05-17, Volume: 43, Issue:20 Topics: Animals; Calcium; Disease Models, Animal; Endoplasmic Reticulum; Female; Glutamic Acid; Huntington Disease; Male; Mice; Mice, Transgenic; Presynaptic Terminals	2023
Single Synapse Indicators of Glutamate Release and Uptake in Acute Brain Slices from Normal and Huntington Mice. Journal of visualized experiments : JoVE, 2020, 03-11, Issue:157 Topics: Animals; Artifacts; Astrocytes; Axons; Brain; Glutamic Acid; Huntington Disease; Mice; Phenotype; Presynaptic Terminals; Synapses	2020
DNAJB6, a Key Factor in Neuronal Sensitivity to Amyloidogenesis. Molecular cell, 2020, 04-16, Volume: 78, Issue:2 Topics: Amyloidogenic Proteins; Cell Differentiation; Gene Expression Regulation; Gene Knockout Techniques; Glutamic Acid; HSP40 Heat-Shock Proteins; Humans; Huntington Disease; Induced Pluripotent Stem Cells; Machado-Joseph Disease; Molecular Chaperones; Nerve Tissue Proteins; Neural Stem Cells; Neurons; Protein Aggregates; Trinucleotide Repeat Expansion	2020
Impaired Replenishment of Cortico-Striatal Synaptic Glutamate in Huntington's Disease Mouse Model. Journal of Huntington's disease, 2020, Volume: 9, Issue:2 Topics: Animals; Cerebral Cortex; Coculture Techniques; Corpus Striatum; Disease Models, Animal; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Immunohistochemistry; Mice; Mice, Inbred Strains; Mice, Transgenic; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Synaptic Vesicles	2020
M2 cortex-dorsolateral striatum stimulation reverses motor symptoms and synaptic deficits in Huntington's disease. eLife, 2020, 10-05, Volume: 9 Topics: Animals; Cerebral Cortex; Corpus Striatum; Electric Stimulation; Glutamic Acid; Huntington Disease; Mice; Motor Activity; Neuronal Plasticity; Neurons; Optogenetics	2020
Synaptic Dysfunction in Huntington's Disease: Lessons from Genetic Animal Models. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 2022, Volume: 28, Issue:1 Topics: Animals; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Glutamic Acid; Humans; Huntington Disease; Mice; Mice, Transgenic; Models, Animal	2022
Protective effect of a spider recombinant toxin in a murine model of Huntington's disease. Neuropeptides, 2021, Volume: 85 Topics: Animals; Disease Models, Animal; Glutamic Acid; Huntington Disease; Mice; Mice, Transgenic; Muscle, Skeletal; Neurons; Neuroprotective Agents; Spider Venoms; Spinal Cord	2021
Differential electrophysiological and morphological alterations of thalamostriatal and corticostriatal projections in the R6/2 mouse model of Huntington's disease. Neurobiology of disease, 2017, Volume: 108 Topics: Animals; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Female; Glutamic Acid; Huntington Disease; Immunohistochemistry; Male; Mice, Transgenic; Microscopy, Electron; Neural Pathways; Neurons; Optogenetics; Patch-Clamp Techniques; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Thalamus; Tissue Culture Techniques	2017
Disease-modifying effects of ganglioside GM1 in Huntington's disease models. EMBO molecular medicine, 2017, Volume: 9, Issue:11 Topics: Animals; Behavior, Animal; Body Weight; Brain; Calcium-Binding Proteins; Disease Models, Animal; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Ferritins; G(M1) Ganglioside; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamic Acid; Huntingtin Protein; Huntington Disease; Infusions, Intraventricular; Mice; Mice, Transgenic; Microfilament Proteins; Serotonin; Survival Rate	2017
Pathway-Specific Control of Striatal Neuron Vulnerability by Corticostriatal Cannabinoid CB1 Receptors. Cerebral cortex (New York, N.Y. : 1991), 2018, 01-01, Volume: 28, Issue:1 Topics: Animals; Astrocytes; Cell Survival; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Genetic Vectors; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Male; Mice, Transgenic; Neural Pathways; Neurons; Receptor, Cannabinoid, CB1; Receptors, Dopamine D1; Receptors, Dopamine D2; Synaptic Transmission	2018
Integrative Characterization of the R6/2 Mouse Model of Huntington's Disease Reveals Dysfunctional Astrocyte Metabolism. Cell reports, 2018, 05-15, Volume: 23, Issue:7 Topics: 3-Hydroxybutyric Acid; Acetates; Animals; Astrocytes; Brain; Disease Models, Animal; Energy Metabolism; Female; Glutamic Acid; Glutamine; Humans; Huntington Disease; Male; Mice, Transgenic; Neurotransmitter Agents; Proteome	2018
In Vivo Multidimensional Brain Imaging in Huntington's Disease Animal Models. Methods in molecular biology (Clifton, N.J.), 2018, Volume: 1780 Topics: Animals; Brain; Contrast Media; Disease Models, Animal; Functional Neuroimaging; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Intravital Microscopy; Magnetic Resonance Imaging; Mice; Mice, Transgenic; Molecular Imaging; Primates; Proton Magnetic Resonance Spectroscopy	2018
Direct assessment of presynaptic modulation of cortico-striatal glutamate release in a Huntington's disease mouse model. Journal of neurophysiology, 2018, 12-01, Volume: 120, Issue:6 Topics: Animals; Calcium; Corpus Striatum; Exocytosis; Glutamic Acid; Huntington Disease; Male; Mice; Presynaptic Terminals; Synaptic Transmission	2018
Decreased expression of GLT-1 in the R6/2 model of Huntington's disease does not worsen disease progression. The European journal of neuroscience, 2013, Volume: 38, Issue:3 Topics: Animals; Behavior, Animal; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Transporter 2; Glutamic Acid; Huntington Disease; Mice; Mice, Transgenic; Presynaptic Terminals	2013
Dysregulation of corticostriatal ascorbate release and glutamate uptake in transgenic models of Huntington's disease. Antioxidants & redox signaling, 2013, Dec-10, Volume: 19, Issue:17 Topics: Animals; Ascorbic Acid; Biological Transport; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Glutamic Acid; Humans; Huntington Disease; Mice; Mice, Transgenic	2013
Enhanced Ca(2+)-dependent glutamate release from astrocytes of the BACHD Huntington's disease mouse model. Neurobiology of disease, 2013, Volume: 58 Topics: Amino Acid Transport Systems, Acidic; Animals; Animals, Newborn; Astrocytes; Calcium; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Glial Fibrillary Acidic Protein; Glutamic Acid; Green Fluorescent Proteins; Huntingtin Protein; Huntington Disease; Mice; Mutation; Nerve Tissue Proteins; Nuclear Proteins; Physical Stimulation; Pyruvate Carboxylase; Subcellular Fractions; Transfection	2013
Synaptic mutant huntingtin inhibits synapsin-1 phosphorylation and causes neurological symptoms. The Journal of cell biology, 2013, Sep-30, Volume: 202, Issue:7 Topics: Age Factors; Animals; Behavior, Animal; Blotting, Western; Brain; Chromatography, Liquid; Dopamine; Exons; Female; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Immunoenzyme Techniques; Immunoprecipitation; Male; Mice; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Neurons; Peptides; Phosphorylation; Presynaptic Terminals; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Synapsins; Synaptic Transmission; Synaptosomal-Associated Protein 25; Tandem Mass Spectrometry	2013
Neurochemical correlates of caudate atrophy in Huntington's disease. Movement disorders : official journal of the Movement Disorder Society, 2014, Volume: 29, Issue:3 Topics: Adult; Aged; Aspartic Acid; Atrophy; Caudate Nucleus; Female; Glutamic Acid; Humans; Huntington Disease; Magnetic Resonance Imaging; Male; Middle Aged; Motor Activity; Mutation; Young Adult	2014
Striatal synaptosomes from Hdh140Q/140Q knock-in mice have altered protein levels, novel sites of methionine oxidation, and excess glutamate release after stimulation. Journal of Huntington's disease, 2013, Volume: 2, Issue:4 Topics: Animals; Blotting, Western; Chromatography, Liquid; Corpus Striatum; Disease Models, Animal; Gene Knock-In Techniques; Glutamic Acid; Huntingtin Protein; Huntington Disease; Methionine; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Nuclear Proteins; Oxidation-Reduction; Synaptosomes; Tandem Mass Spectrometry	2013
Expression, pharmacology and functional activity of adenosine A1 receptors in genetic models of Huntington's disease. Neurobiology of disease, 2014, Volume: 71 Topics: Action Potentials; Adenine; Adenosine A1 Receptor Antagonists; Animals; Cerebral Cortex; Corpus Striatum; Cyclic AMP; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Female; Gene Expression Regulation; Glutamic Acid; Huntingtin Protein; Huntington Disease; In Vitro Techniques; Male; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Potassium Chloride; Protein Binding; Receptor, Adenosine A1; Signal Transduction; Statistics, Nonparametric; Synaptic Transmission; Synaptosomes; Transfection; Trinucleotide Repeat Expansion; Tritium; Xanthines	2014
The mGluR5 positive allosteric modulator, CDPPB, ameliorates pathology and phenotypic signs of a mouse model of Huntington's disease. Neurobiology of disease, 2015, Volume: 73 Topics: Age Factors; Animals; Benzamides; Cell Death; Cells, Cultured; Corpus Striatum; Disease Models, Animal; Embryo, Mammalian; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Mice; Mice, Transgenic; Mitochondria; Motor Activity; Nerve Tissue Proteins; Neurons; Pyrazoles; Recognition, Psychology; Signal Transduction; Synapses	2015
Investigating dynamic structural and mechanical changes of neuroblastoma cells associated with glutamate-mediated neurodegeneration. Scientific reports, 2014, Nov-17, Volume: 4 Topics: Alzheimer Disease; Cell Line, Tumor; Glutamic Acid; Humans; Huntington Disease; Microscopy, Atomic Force; Nerve Degeneration; Neuroblastoma; Receptors, N-Methyl-D-Aspartate	2014
Presymptomatic glutamate levels in prefrontal cortex in the Hdh(CAG150) mouse model of Huntington's disease. Journal of Huntington's disease, 2014, Volume: 3, Issue:4 Topics: Animals; Biomarkers; Disease Models, Animal; Female; Glutamic Acid; Huntingtin Protein; Huntington Disease; Male; Mice; Microdialysis; Nerve Tissue Proteins; Nuclear Proteins; Prefrontal Cortex	2014
HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity. Human molecular genetics, 2015, Jun-01, Volume: 24, Issue:11 Topics: Age of Onset; Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Glutamic Acid; Humans; Huntington Disease; Induced Pluripotent Stem Cells; Mice; Neural Stem Cells	2015
Adult neural progenitor cells from Huntington's disease mouse brain exhibit increased proliferation and migration due to enhanced calcium and ROS signals. Cell proliferation, 2015, Volume: 48, Issue:5 Topics: Animals; Brain; Calcium Signaling; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin Protein; Glutamic Acid; Huntington Disease; Ki-67 Antigen; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Neural Stem Cells; Neuropeptides; Reactive Oxygen Species	2015
Allosteric activation of M4 muscarinic receptors improve behavioral and physiological alterations in early symptomatic YAC128 mice. Proceedings of the National Academy of Sciences of the United States of America, 2015, Nov-10, Volume: 112, Issue:45 Topics: Allosteric Regulation; Animals; Brain; Fluorescence; Glutamic Acid; Huntington Disease; Immunohistochemistry; Mice; Mice, Mutant Strains; Pyridazines; Receptor, Muscarinic M4; Rotarod Performance Test; Synaptic Transmission; Thiophenes	2015
Impaired PLP-dependent metabolism in brain samples from Huntington disease patients and transgenic R6/1 mice. Metabolic brain disease, 2016, Volume: 31, Issue:3 Topics: Adult; Aged; Animals; Cerebral Cortex; Corpus Striatum; Cystathionine; Disease Models, Animal; Disease Progression; Female; Glutamic Acid; Humans; Huntington Disease; Male; Mice; Mice, Transgenic; Middle Aged; Oxidative Stress; Pyridoxal Phosphate; Young Adult	2016
Impaired development of cortico-striatal synaptic connectivity in a cell culture model of Huntington's disease. Neurobiology of disease, 2016, Volume: 87 Topics: Animals; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Dendrites; Disease Models, Animal; Excitatory Postsynaptic Potentials; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Mice, Transgenic; Miniature Postsynaptic Potentials; Nerve Tissue Proteins; Neural Inhibition; Neural Pathways; Patch-Clamp Techniques; Synapses; Synaptic Vesicles	2016
Neuroprotective Activity of Curcumin in Combination with Piperine against Quinolinic Acid Induced Neurodegeneration in Rats. Pharmacology, 2016, Volume: 97, Issue:3-4 Topics: Adenosine; Alkaloids; Animals; Antioxidants; Benzodioxoles; Brain; Catecholamines; Curcumin; Cytokines; Drug Therapy, Combination; gamma-Aminobutyric Acid; Glutamic Acid; Glutathione; Hand Strength; Huntington Disease; Lipid Peroxidation; Locomotion; Neuroprotective Agents; Nitrites; Piperidines; Polyunsaturated Alkamides; Quinolinic Acid; Rats, Wistar	2016
Dysfunctional Calcium and Glutamate Signaling in Striatal Astrocytes from Huntington's Disease Model Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, Mar-23, Volume: 36, Issue:12 Topics: Animals; Astrocytes; Calcium; Corpus Striatum; Female; Glutamic Acid; Huntington Disease; Male; Mice; Mice, Inbred C57BL; Signal Transduction	2016
Real-time imaging of glutamate clearance reveals normal striatal uptake in Huntington disease mouse models. Nature communications, 2016, Apr-07, Volume: 7 Topics: Animals; Astrocytes; Biological Transport; Corpus Striatum; Dependovirus; Disease Models, Animal; Genes, Reporter; Genetic Vectors; Glutamic Acid; Humans; Huntington Disease; Male; Membrane Potentials; Mice; Mice, Transgenic; Optical Imaging; Synapses; Synaptosomes	2016
GluN3A promotes NMDA spiking by enhancing synaptic transmission in Huntington's disease models. Neurobiology of disease, 2016, Volume: 93 Topics: Animals; Corpus Striatum; Disease Models, Animal; Glutamic Acid; Huntington Disease; Memantine; Mice; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission	2016
Functional Indicators of Glutamate Transport in Single Striatal Astrocytes and the Influence of Kir4.1 in Normal and Huntington Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, 05-04, Volume: 36, Issue:18 Topics: Amino Acid Transport System X-AG; Animals; Astrocytes; Benzofurans; Excitatory Amino Acid Transporter 2; Excitatory Postsynaptic Potentials; Gap Junctions; Gene Knock-In Techniques; Glial Fibrillary Acidic Protein; Glutamic Acid; Huntington Disease; Mice; Neostriatum; Patch-Clamp Techniques; Phthalic Acids; Potassium Channels, Inwardly Rectifying	2016
In vivo imaging of brain glutamate defects in a knock-in mouse model of Huntington's disease. NeuroImage, 2016, Oct-01, Volume: 139 Topics: Animals; Brain; Down-Regulation; Female; Gene Knock-In Techniques; Glutamic Acid; Huntington Disease; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Imaging; Neurotransmitter Agents; Proton Magnetic Resonance Spectroscopy	2016
Astrocytes are key but indirect contributors to the development of the symptomatology and pathophysiology of Huntington's disease. Glia, 2016, Volume: 64, Issue:11 Topics: Animals; Astrocytes; Brain; Cyclophilin A; Disease Models, Animal; DNA-Binding Proteins; Dopamine and cAMP-Regulated Phosphoprotein 32; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Humans; Huntingtin Protein; Huntington Disease; Locomotion; Mice; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Neurons; Nuclear Proteins	2016
Similar Progression of Morphological and Metabolic Phenotype in R6/2 Mice with Different CAG Repeats Revealed by In Vivo Magnetic Resonance Imaging and Spectroscopy. Journal of Huntington's disease, 2016, 10-01, Volume: 5, Issue:3 Topics: Animals; Aspartic Acid; Brain; Disease Models, Animal; Disease Progression; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Mice; Mice, Transgenic; Trinucleotide Repeats	2016
Sertraline and venlafaxine improves motor performance and neurobehavioral deficit in quinolinic acid induced Huntington's like symptoms in rats: Possible neurotransmitters modulation. Pharmacological reports : PR, 2017, Volume: 69, Issue:2 Topics: Animals; Corpus Striatum; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Huntington Disease; Interleukin-1beta; Interleukin-6; Lipid Peroxidation; Male; Motor Activity; Neuroprotective Agents; Neurotransmitter Agents; Oxidative Stress; Quinolinic Acid; Rats; Rats, Wistar; Rotarod Performance Test; Sertraline; Tumor Necrosis Factor-alpha; Venlafaxine Hydrochloride	2017
Huntington's disease: modeling the gait disorder and proposing novel treatments. Journal of theoretical biology, 2008, Sep-21, Volume: 254, Issue:2 Topics: Basal Ganglia; Computer Simulation; Diazepam; GABA Modulators; Gait; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Huntington Disease; Models, Biological	2008
MR-spectroscopic findings in juvenile-onset Huntington's disease. Movement disorders : official journal of the Movement Disorder Society, 2008, Oct-15, Volume: 23, Issue:13 Topics: Adolescent; Aspartic Acid; Brain Mapping; Child; Child, Preschool; Creatine; Female; Glutamic Acid; Humans; Huntington Disease; Magnetic Resonance Spectroscopy; Male; Protons; Putamen; Trinucleotide Repeats; Young Adult	2008
Glutamate toxicity in the striatum of the R6/2 Huntington's disease transgenic mice is age-dependent and correlates with decreased levels of glutamate transporters. Neurobiology of disease, 2009, Volume: 34, Issue:1 Topics: Aging; Analysis of Variance; Animals; Blotting, Western; Corpus Striatum; Electroencephalography; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Female; Glutamic Acid; Huntington Disease; Mice; Mice, Transgenic	2009
Ginsenosides protect striatal neurons in a cellular model of Huntington's disease. Journal of neuroscience research, 2009, Volume: 87, Issue:8 Topics: Animals; Calcium Signaling; Cells, Cultured; Corpus Striatum; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Ginsenosides; Glutamic Acid; Huntington Disease; Male; Mice; Mice, Neurologic Mutants; Neurons; Neuroprotective Agents; Neurotoxins; Treatment Outcome	2009
Two novel comments on the treatment of Huntington's disease. The Journal of neuropsychiatry and clinical neurosciences, 2009,Winter, Volume: 21, Issue:1 Topics: Basal Ganglia; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Huntington Disease; Models, Neurological; Movement Disorders	2009
Diminished hippocalcin expression in Huntington's disease brain does not account for increased striatal neuron vulnerability as assessed in primary neurons. Journal of neurochemistry, 2009, Volume: 111, Issue:2 Topics: 3-Hydroxyacyl CoA Dehydrogenases; Animals; Caudate Nucleus; Cell Survival; Cells, Cultured; Female; Glutamic Acid; Hippocalcin; Humans; Huntington Disease; Kidney; Lentivirus; Male; Middle Aged; Mitochondria; Nerve Degeneration; Neuronal Apoptosis-Inhibitory Protein; Neurons; Neurotoxins; Rats; RNA, Messenger	2009
Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms. Proceedings of the National Academy of Sciences of the United States of America, 2009, Dec-29, Volume: 106, Issue:52 Topics: Aging; Animals; Astrocytes; Base Sequence; Brain; DNA Primers; Excitatory Amino Acid Transporter 2; Gene Expression; Glial Fibrillary Acidic Protein; Gliosis; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Mice; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Nuclear Proteins; Phenotype; Promoter Regions, Genetic; Recombinant Proteins; Sp1 Transcription Factor	2009
Mutant huntingtin in glial cells exacerbates neurological symptoms of Huntington disease mice. The Journal of biological chemistry, 2010, Apr-02, Volume: 285, Issue:14 Topics: Animals; Behavior, Animal; Blotting, Western; Brain; Cells, Cultured; Disease Models, Animal; Female; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Immunoenzyme Techniques; Male; Mice; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Neuroglia; Neurons; Nuclear Proteins; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seizures; Trinucleotide Repeat Expansion	2010
Glycolysis inhibition decreases the levels of glutamate transporters and enhances glutamate neurotoxicity in the R6/2 Huntington's disease mice. Neurochemical research, 2010, Volume: 35, Issue:8 Topics: Amino Acid Transport System X-AG; Animals; Brain; Female; Glutamic Acid; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); Glycolysis; Huntington Disease; Iodoacetates; Mice; Mice, Inbred BALB C; Mice, Transgenic	2010
In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects. Human molecular genetics, 2010, Aug-01, Volume: 19, Issue:15 Topics: Aged; Amino Acid Transport System X-AG; Animals; Astrocytes; Biological Transport; Dopamine and cAMP-Regulated Phosphoprotein 32; Down-Regulation; Fluorescent Antibody Technique; Glial Fibrillary Acidic Protein; Glutamic Acid; Humans; Huntington Disease; Lentivirus; Mice; Middle Aged; Mutant Proteins; Neostriatum; Neurons; Peptides; Phenotype; Receptors, N-Methyl-D-Aspartate; Serotonin Plasma Membrane Transport Proteins; Time Factors; Trinucleotide Repeat Expansion	2010
Transcriptomic responses in mouse brain exposed to chronic excess of the neurotransmitter glutamate. BMC genomics, 2010, Jun-07, Volume: 11 Topics: Amino Acids; Animals; Biological Transport; Brain; Calcium Signaling; Chemokines; Focal Adhesion Kinase 2; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Gene Regulatory Networks; Genomics; Glutamate Dehydrogenase; Glutamic Acid; Hippocampus; Huntington Disease; Intracellular Space; Male; Mice; Mice, Transgenic; Neurites; Neuroglia; Neurotransmitter Agents; Oligonucleotide Array Sequence Analysis; Phosphoproteins; Protein Folding; Reproducibility of Results; Signal Transduction; Stress, Physiological; Synapses; Time Factors; Toll-Like Receptors	2010
Glutamate-induced alterations in Ca2+ signaling are modulated by mitochondrial Ca2+ handling capacity in brain slices of R6/1 transgenic mice. The European journal of neuroscience, 2010, Volume: 32, Issue:1 Topics: Animals; Brain; Calcium; Calcium Signaling; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Enzyme Inhibitors; Glutamic Acid; Homeostasis; Humans; Huntington Disease; Male; Membrane Potential, Mitochondrial; Mice; Mice, Transgenic; Mitochondria; NADP; Oxygen Consumption; Reactive Oxygen Species; Thapsigargin; Uncoupling Agents	2010
Palmitoylation and function of glial glutamate transporter-1 is reduced in the YAC128 mouse model of Huntington disease. Neurobiology of disease, 2010, Volume: 40, Issue:1 Topics: Animals; Cell Line; Chlorocebus aethiops; COS Cells; Cysteine; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Transporter 2; Glutamic Acid; Huntington Disease; Lipoylation; Mice; Mice, Transgenic; Mutagenesis, Site-Directed; Neuroglia; Rats	2010
Modulation of lipid peroxidation and mitochondrial function improves neuropathology in Huntington's disease mice. Acta neuropathologica, 2011, Volume: 121, Issue:4 Topics: Adenosine Triphosphate; Age Factors; Aldehydes; Analysis of Variance; Animals; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Embryo, Mammalian; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Imaging, Three-Dimensional; In Situ Nick-End Labeling; Indoles; Lipid Peroxidation; Lipoxygenase Inhibitors; Male; Masoprocol; Membrane Potential, Mitochondrial; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Mitochondria; Neostriatum; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Oxidative Stress; Synapses; Tetrazolium Salts; Thiazoles; Trinucleotide Repeat Expansion	2011
Differential electrophysiological changes in striatal output neurons in Huntington's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Jan-26, Volume: 31, Issue:4 Topics: Action Potentials; Age Factors; Animals; Corpus Striatum; Dendritic Spines; Dopamine; Excitatory Postsynaptic Potentials; Glutamic Acid; Green Fluorescent Proteins; Huntington Disease; In Vitro Techniques; Mice; Mice, Mutant Strains; Motor Activity; Neurons; Promoter Regions, Genetic; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior; Synaptic Transmission; Tetrabenazine	2011
Neuronal store-operated calcium entry pathway as a novel therapeutic target for Huntington's disease treatment. Chemistry & biology, 2011, Jun-24, Volume: 18, Issue:6 Topics: Animals; Apoptosis; Calcium; Cells, Cultured; Disease Models, Animal; Drosophila; Fura-2; Glutamic Acid; Huntingtin Protein; Huntington Disease; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neurons; NF-kappa B; Nuclear Proteins; Phenyl Ethers; Quinazolines; RNA Interference; RNA, Small Interfering; TRPC Cation Channels	2011
Dantrolene is neuroprotective in Huntington's disease transgenic mouse model. Molecular neurodegeneration, 2011, Nov-25, Volume: 6 Topics: Animals; Apoptosis; Caffeine; Calcium; Calcium Signaling; Cells, Cultured; Central Nervous System Stimulants; Corpus Striatum; Dantrolene; Disease Models, Animal; Glutamic Acid; Huntington Disease; Mice; Mice, Transgenic; Motor Activity; Muscle Relaxants, Central; Neurons; Neuroprotective Agents	2011
Cell type-specific localization of optineurin in the striatal neurons of mice: implications for neuronal vulnerability in Huntington's disease. Neuroscience, 2012, Jan-27, Volume: 202 Topics: Animals; Blotting, Western; Cell Cycle Proteins; Cell Death; Corpus Striatum; Densitometry; Eye Proteins; Glutamic Acid; Huntington Disease; Image Processing, Computer-Assisted; Immunohistochemistry; Interneurons; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neurons; Serotonin Plasma Membrane Transport Proteins	2012
A novel target for Huntington's disease: ERK at the crossroads of signaling. The ERK signaling pathway is implicated in Huntington's disease and its upregulation ameliorates pathology. BioEssays : news and reviews in molecular, cellular and developmental biology, 2012, Volume: 34, Issue:2 Topics: Animals; Brain-Derived Neurotrophic Factor; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; MAP Kinase Signaling System; Nerve Tissue Proteins; Nuclear Proteins	2012
Glutamate-based depression GBD. Medical hypotheses, 2012, Volume: 78, Issue:5 Topics: Affect; Alzheimer Disease; Arthritis, Rheumatoid; Chronic Pain; Cognition; Coronary Artery Disease; Depression; Diabetes Complications; Fibromyalgia; Glutamic Acid; Gyrus Cinguli; Humans; Huntington Disease; Inflammation; Interferons; Models, Neurological; Models, Psychological; Parkinson Disease; Receptors, N-Methyl-D-Aspartate; Risk Factors; Stroke; Synaptic Transmission	2012
Brain metabolite alterations and cognitive dysfunction in early Huntington's disease. Movement disorders : official journal of the Movement Disorder Society, 2012, Volume: 27, Issue:7 Topics: Adult; Analysis of Variance; Aspartic Acid; Brain; Cognition Disorders; Female; Glutamic Acid; Humans; Huntington Disease; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Regression Analysis; Trinucleotide Repeat Expansion	2012
Characterization of neurophysiological and behavioral changes, MRI brain volumetry and 1H MRS in zQ175 knock-in mouse model of Huntington's disease. PloS one, 2012, Volume: 7, Issue:12 Topics: Animals; Behavior, Animal; Body Weight; Brain; Cell Count; Disease Models, Animal; Disease Progression; Endpoint Determination; Female; Gene Knock-In Techniques; Glutamic Acid; Huntington Disease; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mice; Neostriatum; Nerve Tissue Proteins; Neurons; Neurophysiology; Organ Size; Repetitive Sequences, Nucleic Acid; Swimming; Synaptic Transmission	2012
Impaired glutamate transport and glutamate-glutamine cycling: downstream effects of the Huntington mutation. Brain : a journal of neurology, 2002, Volume: 125, Issue:Pt 8 Topics: Aging; Animals; Biological Transport; Brain; Cerebral Cortex; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Female; Glutamic Acid; Glutamine; Humans; Huntingtin Protein; Huntington Disease; Immunohistochemistry; Male; Mice; Mice, Transgenic; Microdialysis; Mutation; Nerve Tissue Proteins; Nuclear Proteins	2002
Genetic background of Huntington disease in Croatia: Molecular analysis of CAG, CCG, and Delta2642 (E2642del) polymorphisms. Human mutation, 2002, Volume: 20, Issue:3 Topics: Alleles; Croatia; DNA; Gene Frequency; Glutamic Acid; Haplotypes; Humans; Huntington Disease; Polymorphism, Genetic; Trinucleotide Repeats	2002
Riluzole prolongs survival time and alters nuclear inclusion formation in a transgenic mouse model of Huntington's disease. Movement disorders : official journal of the Movement Disorder Society, 2002, Volume: 17, Issue:4 Topics: Animals; Cell Nucleus; Cerebral Cortex; Corpus Striatum; Excitatory Amino Acid Antagonists; Exons; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Immunoenzyme Techniques; Mice; Mice, Transgenic; Motor Skills; Nerve Tissue Proteins; Neuroprotective Agents; Nuclear Proteins; Riluzole; Survival Analysis; Trinucleotide Repeats	2002
Transient and progressive electrophysiological alterations in the corticostriatal pathway in a mouse model of Huntington's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Feb-01, Volume: 23, Issue:3 Topics: Animals; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Disease Progression; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; Huntington Disease; In Vitro Techniques; Mice; Neural Pathways; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Potassium Channel Blockers; Riluzole; Tetrodotoxin	2003
A dual role of adenosine A2A receptors in 3-nitropropionic acid-induced striatal lesions: implications for the neuroprotective potential of A2A antagonists. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Jun-15, Volume: 23, Issue:12 Topics: Adenosine; Animals; Body Weight; Cell Death; Corpus Striatum; Disease Models, Animal; Drug Administration Schedule; Encephalitis; Genetic Predisposition to Disease; Glutamic Acid; Huntington Disease; Male; Mice; Mice, Knockout; Neuroprotective Agents; Nitro Compounds; Phenethylamines; Propionates; Rats; Rats, Inbred Lew; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; RNA, Messenger; Signal Transduction; Survival Rate; Synapses; Xanthines	2003
Adenosine A(2A) antagonism increases striatal glutamate outflow in the quinolinic acid rat model of Huntington's disease. Brain research, 2003, Jul-25, Volume: 979, Issue:1-2 Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Extracellular Space; Glutamic Acid; Huntington Disease; Male; Microdialysis; Models, Animal; Neuroprotective Agents; Purinergic P1 Receptor Antagonists; Pyrimidines; Quinolinic Acid; Rats; Rats, Wistar; Receptor, Adenosine A2A; Time Factors; Triazoles	2003
Abnormal association of mutant huntingtin with synaptic vesicles inhibits glutamate release. Human molecular genetics, 2003, Aug-15, Volume: 12, Issue:16 Topics: Animals; Brain Chemistry; Glutamic Acid; Huntingtin Protein; Huntington Disease; Immunohistochemistry; Mice; Mice, Transgenic; Microscopy, Immunoelectron; Nerve Tissue Proteins; Nuclear Proteins; Presynaptic Terminals; Recombinant Fusion Proteins; Synaptic Vesicles	2003
Differential responsiveness of rat striatal nerve endings to the mitochondrial toxin 3-nitropropionic acid: implications for Huntington's disease. The European journal of neuroscience, 2003, Volume: 18, Issue:4 Topics: Acetylcholine; Animals; Convulsants; Corpus Striatum; Dopamine; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Huntington Disease; Male; Mitochondria; Nitro Compounds; Organ Culture Techniques; Potassium Channels; Propionates; Rats; Rats, Sprague-Dawley; Riluzole; Sodium Channels; Succinate Dehydrogenase; Synaptosomes; Tetrodotoxin	2003
Inhibition of mitochondrial complex II alters striatal expression of genes involved in glutamatergic and dopaminergic signaling: possible implications for Huntington's disease. Neurobiology of disease, 2004, Volume: 15, Issue:2 Topics: Animals; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Electron Transport Complex II; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glutamic Acid; Huntington Disease; In Vitro Techniques; Neostriatum; Nerve Tissue Proteins; Nitro Compounds; Oligonucleotide Array Sequence Analysis; Phosphoproteins; Phosphoric Monoester Hydrolases; Propionates; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Signal Transduction; Succinate Dehydrogenase	2004
Adenosine and glutamate extracellular concentrations and mitogen-activated protein kinases in the striatum of Huntington transgenic mice. Selective antagonism of adenosine A2A receptors reduces transmitter outflow. Neurobiology of disease, 2004, Volume: 17, Issue:1 Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Corpus Striatum; Extracellular Fluid; Glutamic Acid; Huntington Disease; Male; Mice; Mice, Inbred CBA; Mice, Transgenic; Mitogen-Activated Protein Kinases; Pyrimidines; Receptor, Adenosine A2A; Triazoles	2004
Dearth of glutamate transporters contributes to striatal excitotoxicity. Experimental neurology, 2004, Volume: 189, Issue:2 Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Antisense Elements (Genetics); Carrier Proteins; Cell Membrane; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hippocampus; Huntington Disease; Neostriatum; Neurons; Neurotoxins; Symporters	2004
Heterogeneity in 1H-MRS profiles of presymptomatic and early manifest Huntington's disease. Brain research, 2005, Jan-07, Volume: 1031, Issue:1 Topics: Adult; Age of Onset; Aged; Aspartic Acid; Early Diagnosis; Female; Glutamic Acid; Glutamine; Humans; Huntington Disease; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Putamen	2005
Minocycline in phenotypic models of Huntington's disease. Neurobiology of disease, 2005, Volume: 18, Issue:1 Topics: Animals; Calpain; Caspases; Cell Death; Cells, Cultured; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalitis; Glutamic Acid; Huntingtin Protein; Huntington Disease; Male; Minocycline; Nerve Degeneration; Nerve Tissue Proteins; Neuroprotective Agents; Nitro Compounds; Nuclear Proteins; Phenotype; Propionates; Quinolinic Acid; Rats; Rats, Inbred Lew; Rats, Wistar; Staurosporine	2005
Expanded polyglutamine peptides disrupt EGF receptor signaling and glutamate transporter expression in Drosophila. Human molecular genetics, 2005, Mar-01, Volume: 14, Issue:5 Topics: Animals; Drosophila melanogaster; ErbB Receptors; Excitatory Amino Acid Transporter 1; Extracellular Signal-Regulated MAP Kinases; Eye; Genes, Reporter; Glutamic Acid; Huntington Disease; Longevity; Neuroglia; Peptides; ras Proteins; Signal Transduction; Up-Regulation	2005
Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease. Proceedings of the National Academy of Sciences of the United States of America, 2005, Feb-15, Volume: 102, Issue:7 Topics: Animals; Apoptosis; Calcium Signaling; Chromosomes, Artificial, Bacterial; Disease Models, Animal; Glutamic Acid; Humans; Huntington Disease; In Vitro Techniques; Mice; Mice, Transgenic; Models, Neurological; Nerve Degeneration; Neurons	2005
Arvanil, a hybrid endocannabinoid and vanilloid compound, behaves as an antihyperkinetic agent in a rat model of Huntington's disease. Brain research, 2005, Jul-19, Volume: 1050, Issue:1-2 Topics: Animals; Brain Chemistry; Capsaicin; Convulsants; Disease Models, Animal; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Huntington Disease; Hyperkinesis; Male; Motor Activity; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley	2005
Increased calbindin-D28k immunoreactivity in striatal projection neurons of R6/2 Huntington's disease transgenic mice. Neurobiology of disease, 2005, Volume: 20, Issue:3 Topics: Animals; Calbindin 1; Calbindins; Calcium Signaling; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Immunohistochemistry; Male; Mice; Mice, Transgenic; Mutation; Neostriatum; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neurotoxins; Nuclear Proteins; RNA, Messenger; S100 Calcium Binding Protein G; Trinucleotide Repeat Expansion; Up-Regulation	2005
UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2006, Volume: 16, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Arachidonic Acids; Brain Chemistry; Disease Models, Animal; Disease Progression; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Encephalomyelitis, Autoimmune, Experimental; Endocannabinoids; Exploratory Behavior; Furans; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Huntington Disease; Male; Malonates; Movement Disorders; Multiple Sclerosis; Nitro Compounds; Oxidopamine; Polyunsaturated Alkamides; Propionates; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine 3-Monooxygenase	2006
Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity. The Journal of cell biology, 2005, Dec-19, Volume: 171, Issue:6 Topics: Adult; Aged; Animals; Astrocytes; Brain; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glutamic Acid; Humans; Huntington Disease; Mice; Mice, Transgenic; Middle Aged; Neuroglia; Rats; Serotonin Plasma Membrane Transport Proteins	2005
Mutant huntingtin aggregates impair mitochondrial movement and trafficking in cortical neurons. Neurobiology of disease, 2006, Volume: 22, Issue:2 Topics: Animals; Buffers; Calcium; Cells, Cultured; Cerebral Cortex; Cytoplasmic Streaming; Cytoskeleton; Cytosol; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Inclusion Bodies; Mitochondria; Mutation; Nerve Tissue Proteins; Neurons; Neurotoxins; Nuclear Proteins; Protein Transport; Rats; Rats, Sprague-Dawley; Transfection	2006
Evaluation of clinically relevant glutamate pathway inhibitors in in vitro model of Huntington's disease. Neuroscience letters, 2006, Oct-30, Volume: 407, Issue:3 Topics: Amines; Animals; Apoptosis; Cells, Cultured; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Folic Acid; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Huntington Disease; Lamotrigine; Male; Memantine; Mice; Mice, Transgenic; Neurons; Neuroprotective Agents; Riluzole; Triazines	2006
Deficits of glutamate transmission in the striatum of toxic and genetic models of Huntington's disease. Neuroscience letters, 2006, Dec-13, Volume: 410, Issue:1 Topics: Animals; Corpus Striatum; Disease Models, Animal; Excitatory Postsynaptic Potentials; Glutamic Acid; Huntington Disease; In Vitro Techniques; Male; Mice; Mice, Transgenic; Neurons; Nitro Compounds; Patch-Clamp Techniques; Propionates; Rats; Rats, Sprague-Dawley; Synaptic Transmission	2006
Abnormal intracortical facilitation in early-stage Huntington's disease. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2007, Volume: 118, Issue:5 Topics: Action Potentials; Adult; Disease Progression; Electromyography; Female; Glutamic Acid; Humans; Huntington Disease; Male; Middle Aged; Motor Cortex; Neural Conduction; Transcranial Magnetic Stimulation	2007
Behavioral and electrophysiological effects of the adenosine A2A receptor antagonist SCH 58261 in R6/2 Huntington's disease mice. Neurobiology of disease, 2007, Volume: 28, Issue:2 Topics: Adenosine A2 Receptor Antagonists; Animals; Behavior, Animal; Brain; Corpus Striatum; Disease Models, Animal; Excitatory Amino Acid Agonists; Glutamic Acid; Huntington Disease; Learning Disabilities; Maze Learning; Mental Disorders; Mice; Mice, Transgenic; Motor Activity; Neuroprotective Agents; Organ Culture Techniques; Pyrimidines; Receptor, Adenosine A2A; Triazoles	2007
Glutamate uptake is reduced in prefrontal cortex in Huntington's disease. Neurochemical research, 2008, Volume: 33, Issue:2 Topics: Astrocytes; Biological Transport; Glutamic Acid; Humans; Huntington Disease; Prefrontal Cortex; Trinucleotide Repeats	2008
Reduced activity of cortico-striatal fibres in the R6/2 mouse model of Huntington's disease. Neuroreport, 2007, Dec-03, Volume: 18, Issue:18 Topics: Aging; Animals; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Down-Regulation; Extracellular Fluid; Female; Gene Expression Regulation; Glutamic Acid; Huntington Disease; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microdialysis; Neural Pathways; Synaptic Transmission	2007
Up-regulation of GLT1 expression increases glutamate uptake and attenuates the Huntington's disease phenotype in the R6/2 mouse. Neuroscience, 2008, Apr-22, Volume: 153, Issue:1 Topics: Animals; Ceftriaxone; Corpus Striatum; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Extracellular Fluid; Glutamic Acid; Huntington Disease; Male; Maze Learning; Mice; Mice, Transgenic; Phenotype; Synaptic Transmission; Up-Regulation	2008
Full length mutant huntingtin is required for altered Ca2+ signaling and apoptosis of striatal neurons in the YAC mouse model of Huntington's disease. Neurobiology of disease, 2008, Volume: 31, Issue:1 Topics: Animals; Apoptosis; Calcium Signaling; Corpus Striatum; Disease Models, Animal; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; In Situ Nick-End Labeling; Membrane Potential, Mitochondrial; Mice; Mice, Transgenic; Mutant Proteins; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate	2008
The absence of unique kainic acid-like molecules in urine, serum, and CSF from Huntington's disease patients. Journal of the neurological sciences, 1981, Volume: 51, Issue:3 Topics: Animals; Binding, Competitive; Brain; Glutamates; Glutamic Acid; Huntington Disease; Kainic Acid; Ketoglutaric Acids; Male; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Kainic Acid	1981
Platelet glutamate and aspartate uptake in Huntington's disease. Journal of neurochemistry, 1981, Volume: 37, Issue:4 Topics: Aspartic Acid; Biological Transport; Blood Platelets; Glutamates; Glutamic Acid; Humans; Huntington Disease; Kinetics; Reference Values	1981
Normal cerebrospinal fluid and brain glutamate levels in schizophrenia do not support the hypothesis of glutamatergic neuronal dysfunction. Neuroscience letters, 1982, Jan-22, Volume: 28, Issue:1 Topics: Adult; Brain; Glutamates; Glutamic Acid; Humans; Huntington Disease; Middle Aged; Schizophrenia	1982
Huntington's disease. Glutamate and aspartate metabolism in blood platelets. Journal of the neurological sciences, 1982, Volume: 53, Issue:3 Topics: Adult; Asparagine; Aspartic Acid; Blood Platelets; Female; Glutamates; Glutamic Acid; Glutamine; Humans; Huntington Disease; Kinetics; Male; Middle Aged	1982
Effects of kainic acid injection and cortical lesion on ornithine and aspartate aminotransferases in rat striatum. Journal of neuroscience research, 1982, Volume: 8, Issue:4 Topics: Animals; Aspartate Aminotransferases; Corpus Striatum; Frontal Lobe; Glutamates; Glutamic Acid; Humans; Huntington Disease; Kainic Acid; Muridae; Neural Pathways; Ornithine-Oxo-Acid Transaminase; Parietal Lobe; Pyrrolidines; Transaminases	1982
Neuronal [3H]benzodiazepine binding and levels of GABA, glutamate, and taurine are normal in Huntington's disease cerebellum. Journal of neurochemistry, 1983, Volume: 41, Issue:5 Topics: Amino Acids; Cerebellum; Flunitrazepam; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Haloperidol; Humans; Huntington Disease; Middle Aged; Neurons; Receptors, Cell Surface; Receptors, GABA-A; Taurine	1983
Vulnerability of medium spiny striatal neurons to glutamate: role of Na+/K+ ATPase. The European journal of neuroscience, 1995, Aug-01, Volume: 7, Issue:8 Topics: Animals; Brain; Corpus Striatum; Dose-Response Relationship, Drug; Energy Metabolism; Glutamic Acid; Huntington Disease; N-Methylaspartate; Neurons; Ouabain; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase	1995
AMPA and NMDA binding sites in the hypothalamic lateral tuberal nucleus: implications for Huntington's disease. Neurology, 1993, Volume: 43, Issue:8 Topics: Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Glutamates; Glutamic Acid; Humans; Huntington Disease; Hypothalamic Area, Lateral; Ibotenic Acid; Kainic Acid; Middle Aged; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate	1993
Neurochemical substrates of rigidity and chorea in Huntington's disease. Brain : a journal of neurology, 1993, Volume: 116 ( Pt 5) Topics: Adolescent; Adult; Aged; Basal Ganglia; Child; Enkephalin, Methionine; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Huntington Disease; Male; Middle Aged; Models, Biological; Muscle Rigidity; Substance P; Thalamus	1993
Huntington's disease: the neuroexcitotoxin aspartate is increased in platelets and decreased in plasma. Journal of the neurological sciences, 1994, Dec-01, Volume: 127, Issue:1 Topics: Adult; Aspartic Acid; Blood Platelets; Blood Proteins; Chromatography, High Pressure Liquid; Female; Glutamic Acid; Glutamine; Humans; Huntington Disease; Male; Middle Aged; Phenylalanine; Plasma	1994
Ancestral differences in the distribution of the delta 2642 glutamic acid polymorphism is associated with varying CAG repeat lengths on normal chromosomes: insights into the genetic evolution of Huntington disease. Human molecular genetics, 1995, Volume: 4, Issue:2 Topics: Alleles; Asian People; Biological Evolution; Black People; China; Chromosomes, Human; Europe; Gene Frequency; Glutamic Acid; Haplotypes; Humans; Huntington Disease; Japan; Pedigree; Polymorphism, Restriction Fragment Length; Repetitive Sequences, Nucleic Acid; White People	1995
Brain extracts containing a Huntington disease antigen inhibit [3H]kainate binding and block synaptosomal amino acid transport. Neurochemistry international, 1993, Volume: 23, Issue:2 Topics: Amino Acids; Animals; Antigens; Biological Transport; Brain; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; Huntington Disease; Kainic Acid; Rats; Rats, Sprague-Dawley; Synaptosomes; Tissue Extracts; Tritium	1993
Mitochondrial defect in Huntington's disease caudate nucleus. Annals of neurology, 1996, Volume: 39, Issue:3 Topics: Aged; Caudate Nucleus; Chromosomes, Human, Pair 4; Culture Techniques; DNA, Mitochondrial; Electron Transport Complex III; Energy Metabolism; Gene Expression; Glutamic Acid; Humans; Huntington Disease; Middle Aged; NAD(P)H Dehydrogenase (Quinone); RNA, Messenger	1996
Proton magnetic resonance spectroscopy in Huntington's disease: evidence in favour of the glutamate excitotoxic theory. Movement disorders : official journal of the Movement Disorder Society, 1996, Volume: 11, Issue:2 Topics: Aspartic Acid; Cerebral Cortex; Corpus Striatum; Genetic Carrier Screening; Glutamic Acid; Glutamine; Humans; Huntington Disease; Magnetic Resonance Imaging; Nerve Degeneration; Reference Values; Synaptic Transmission	1996
Etiology of (CAG)n triplet repeat neurodegenerative diseases such as Huntington's disease is connected to stimulation of glutamate receptors. Medical hypotheses, 1997, Volume: 48, Issue:5 Topics: Autoimmunity; Cerebrovascular Disorders; Epilepsy; Glutamic Acid; Humans; Huntington Disease; Minisatellite Repeats; Models, Biological; Nerve Degeneration; Receptors, Glutamate; Trinucleotide Repeats	1997
Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene. Proceedings of the National Academy of Sciences of the United States of America, 1998, May-26, Volume: 95, Issue:11 Topics: Animals; Brain; Dopamine; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Mice; Mice, Transgenic; Nerve Tissue Proteins; Nuclear Proteins; Radioligand Assay; Receptors, Dopamine; Receptors, Glutamate; Transfection	1998
Electrophysiology of the neuroprotective agent riluzole on striatal spiny neurons. Neuropharmacology, 1998, Volume: 37, Issue:8 Topics: Animals; Corpus Striatum; Disease Models, Animal; Excitatory Postsynaptic Potentials; Glutamic Acid; Huntington Disease; Male; Membrane Potentials; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Rats; Rats, Wistar; Riluzole	1998
Brain neurotransmitter deficits in mice transgenic for the Huntington's disease mutation. Journal of neurochemistry, 1999, Volume: 72, Issue:4 Topics: Animals; Brain Chemistry; Disease Models, Animal; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Huntingtin Protein; Huntington Disease; Hydroxyindoleacetic Acid; Mice; Mice, Transgenic; Mutation; Nerve Degeneration; Nerve Tissue Proteins; Norepinephrine; Nuclear Proteins; Serotonin; Trinucleotide Repeats	1999
Metabolic and glutamatergic disturbances in the Huntington's disease transgenic mouse. Annals of the New York Academy of Sciences, 1999, Volume: 893 Topics: Animals; Brain; Electron Transport Complex IV; Energy Metabolism; Glutamic Acid; Huntington Disease; L-Lactate Dehydrogenase; Mice; Mice, Transgenic; Receptors, Glutamate; Sodium-Potassium-Exchanging ATPase; Succinate Dehydrogenase	1999
3-Nitropropionic acid neurotoxicity in organotypic striatal and corticostriatal slice cultures is dependent on glucose and glutamate. Experimental neurology, 2000, Volume: 164, Issue:1 Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Glucose; Glutamate Decarboxylase; Glutamic Acid; Huntington Disease; In Vitro Techniques; Mitochondria; Nitro Compounds; Propionates; Rats; Succinate Dehydrogenase; Tetrodotoxin	2000
Altered striatal amino acid neurotransmitter release monitored using microdialysis in R6/1 Huntington transgenic mice. The European journal of neuroscience, 2001, Volume: 13, Issue:1 Topics: Amino Acids; Animals; Aspartic Acid; Corpus Striatum; gamma-Aminobutyric Acid; Glutamic Acid; Huntington Disease; Mice; Mice, Transgenic; Microdialysis; N-Methylaspartate; Neurotransmitter Agents; Potassium Chloride	2001
Partial resistance to malonate-induced striatal cell death in transgenic mouse models of Huntington's disease is dependent on age and CAG repeat length. Journal of neurochemistry, 2001, Volume: 78, Issue:4 Topics: Aging; Amino Acid Chloromethyl Ketones; Animals; bcl-X Protein; Blood Glucose; Cell Death; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Immunoblotting; Immunohistochemistry; Male; Malonates; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Nuclear Proteins; Proteins; Proto-Oncogene Proteins c-bcl-2; Succinate Dehydrogenase; Synaptosomes; Trinucleotide Repeats; X-Linked Inhibitor of Apoptosis Protein	2001
Impaired glutamate uptake in the R6 Huntington's disease transgenic mice. Neurobiology of disease, 2001, Volume: 8, Issue:5 Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; Biological Transport; Carrier Proteins; Cerebral Cortex; Corpus Striatum; Crosses, Genetic; Disease Models, Animal; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glial Fibrillary Acidic Protein; Glutamate Plasma Membrane Transport Proteins; Glutamate-Ammonia Ligase; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Models, Neurological; Nerve Tissue Proteins; Nuclear Proteins; Peptides; Phenotype; RNA, Messenger; Symporters	2001
Blockade of striatal adenosine A2A receptor reduces, through a presynaptic mechanism, quinolinic acid-induced excitotoxicity: possible relevance to neuroprotective interventions in neurodegenerative diseases of the striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Mar-01, Volume: 22, Issue:5 Topics: Animals; Behavior, Animal; Calcium; Cells, Cultured; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Excitatory Amino Acid Antagonists; Gliosis; Glutamic Acid; Hippocampus; Huntington Disease; Long-Term Potentiation; Male; Maze Learning; Motor Activity; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Presynaptic Terminals; Purinergic P1 Receptor Antagonists; Pyrimidines; Quinolinic Acid; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Triazoles	2002
The cortical lesion of Huntington's disease: further neurochemical characterization, and reproduction of some of the histological and neurochemical features by N-methyl-D-aspartate lesions of rat cortex. Annals of neurology, 1992, Volume: 32, Issue:4 Topics: Age Factors; Aged; Animals; Aspartic Acid; Brain Chemistry; Cholecystokinin; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Humans; Huntington Disease; Male; Middle Aged; N-Methylaspartate; Neurochemistry; Rats; Rats, Sprague-Dawley; Somatostatin; Substance P	1992
Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis. The New England journal of medicine, 1992, May-28, Volume: 326, Issue:22 Topics: Aged; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Biological Transport; Brain; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Huntington Disease; In Vitro Techniques; Male; Middle Aged; Motor Cortex; Phenylalanine; Somatosensory Cortex; Spinal Cord; Synaptosomes; Visual Cortex	1992
Dementia in Huntington's disease is associated with neurochemical deficits in the caudate nucleus, not the cerebral cortex. Neuroscience letters, 1990, May-18, Volume: 113, Issue:1 Topics: Adult; Aged; Caudate Nucleus; Cerebral Cortex; Choline O-Acetyltransferase; Dementia; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Huntington Disease; Male; Middle Aged; Neurotransmitter Agents	1990
Characterization and mechanism of glutamate neurotoxicity in primary striatal cultures. Brain research, 1990, Jun-25, Volume: 521, Issue:1-2 Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cells, Cultured; Corpus Striatum; Glutamates; Glutamic Acid; Huntington Disease; Magnesium; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate	1990
Decreased glutamic acid and increased 5-hydroxytryptamine in Huntington's disease brain. Neuroscience letters, 1987, Jul-22, Volume: 78, Issue:2 Topics: Brain Chemistry; gamma-Aminobutyric Acid; Globus Pallidus; Glutamates; Glutamic Acid; Hippocampus; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Putamen; Serotonin; Temporal Lobe	1987
Alterations in L-glutamate binding in Alzheimer's and Huntington's diseases. Science (New York, N.Y.), 1985, Mar-22, Volume: 227, Issue:4693 Topics: Alzheimer Disease; Autoradiography; Binding Sites; Brain; Caudate Nucleus; Cerebral Cortex; Choline O-Acetyltransferase; Glutamates; Glutamic Acid; Humans; Huntington Disease; Putamen; Receptors, Glutamate; Receptors, Neurotransmitter	1985
The mechanism of glutamate-induced degeneration of cultured Huntington's disease and control fibroblasts. Journal of the neurological sciences, 1985, Volume: 70, Issue:1 Topics: Cells, Cultured; Cystine; Fibroblasts; Glutamates; Glutamic Acid; Glutathione; Homocysteine; Humans; Huntington Disease	1985
L-Homocysteic acid as an alternative cytotoxin for studying glutamate-induced cellular degeneration of Huntington's disease and normal skin fibroblasts. Life sciences, 1985, Oct-21, Volume: 37, Issue:16 Topics: Aspartic Acid; Cell Survival; Cells, Cultured; Cysteic Acid; Cysteine; Fibroblasts; Glutamates; Glutamic Acid; Homocysteine; Humans; Huntington Disease; In Vitro Techniques; Isomerism; Kainic Acid; Kinetics; N-Methylaspartate; Neurotransmitter Agents; Skin; Time Factors	1985
Reduced high-affinity glutamate uptake sites in the brains of patients with Huntington's disease. Neuroscience letters, 1986, Jun-18, Volume: 67, Issue:2 Topics: Aged; Aspartic Acid; Brain; Caudate Nucleus; Female; Frontal Lobe; Glutamates; Glutamic Acid; Hippocampus; Humans; Huntington Disease; Male; Middle Aged; Paroxetine; Piperidines; Putamen	1986
Neurons containing NADPH-diaphorase are selectively resistant to quinolinate toxicity. Science (New York, N.Y.), 1986, Oct-03, Volume: 234, Issue:4772 Topics: Animals; Aspartic Acid; Glutamates; Glutamic Acid; Humans; Huntington Disease; Kainic Acid; Mice; N-Methylaspartate; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; Neurons; Oxadiazoles; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid	1986
Huntington's disease: studies on brain free amino acids. Life sciences, 1988, Volume: 42, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Aspartic Acid; Brain; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Histidine; Humans; Huntington Disease; Lysine; Male; Middle Aged; Putamen; Serine; Taurine	1988