glutamic acid and Aging

glutamic acid has been researched along with Aging in 617 studies

Research

Studies (617)

Timeframe	Studies, this research(%)	All Research%
pre-1990	55 (8.91)	18.7374
1990's	174 (28.20)	18.2507
2000's	213 (34.52)	29.6817
2010's	150 (24.31)	24.3611
2020's	25 (4.05)	2.80

Authors

Authors	Studies
Bhattacharya, S; Hong, H; Hunsberger, HC; McDonald, KL; Pfitzer, JC; Reed, MN; Rudy, CC; Setti, SE; Suppiramaniam, V; Weitzner, DS	1
Davydova, TV; Gruden, MA; Ratmirov, AM; Sewell, RDE	2
Antonenko, AK; Fursova, AZ; Kolosova, NG; Telegina, DV	1
Hu, D; Hu, L; Jiao, D; Li, G; Li, X; Li, Z; Liu, S; Qi, L; Wu, H; Zhao, C	1
Chen, C; Du, G; Gao, L; Li, M; Qin, X; Yang, L; Zhou, Y	1
Charzynska, A; Kossut, M; Liguz-Lecznar, M; Maciej Stepniewski, T; Misiewicz, Z; Rozycka, A; Sobolewska, A	1
Chen, Y; Gao, X; Liu, Q; Mao, S; Mu, K; Ou, J; Wang, Q; Wu, N; Zeng, L; Zhang, D; Zhang, K; Zou, H	1
Brewer, GJ; Glabe, CG; Herrera, RA; Philipp, S; Reyes-Ruiz, JM; Sosna, J	1
Elkahloun, AG; Saavedra, JM	1
Al-Harthi, L; Gonzalez, H; Podany, A; Wallace, J	1
Awatramani, R; Heymann, G; Hunker, AC; Krayushkina, D; Soden, ME; Zweifel, LS	1
Glasgow, SD; Kennedy, TE; Marcal, N; Ruthazer, ES; Séguéla, P; Thompson-Steckel, G; Wong, EW	1
Davydova, TV; Gruden, MA; Kudrin, VS; Narkevich, VB; Sewell, RDE; Vetrile, LA; Zakharova, IA	3
D'Adamio, L; Norris, KA; Ren, S; Tambini, MD; Yao, W; Yin, T	1
Auerbach, EJ; Deelchand, DK; Eberly, LE; Hemmy, LS; Marjańska, M; McCarten, JR	1
Billard, JM; Freret, T; Ploux, E	1
Chen, L; Dai, J; Wang, Z	1
Hardingham, GE; Todd, AC	1
Idrizi, A; Mano, I; Mendelowitz, ZZ	1
Brazhe, A; Denisov, P; Lazareva, N; Li, L; Popov, A; Semyanov, A; Sutyagina, O; Verkhratsky, A	1
Elgueta-Reyes, M; Martínez-Pinto, J; Renard, GM; Sotomayor-Zárate, R	1
Chen, QY; Lee, JA; Li, XH; Miao, Z; Zhuo, M	1
Donaldson, PJ; Li, B; Lim, JC; Martis, RM	1
Nikolova, S; Stark, CEL; Stark, SM	1
Deelchand, DK; Grant, A; Hemmy, LS; Hodges, J; Marjańska, M; McCarten, JR; Terpstra, M	1
Chen, K; Godfrey, DA; Mustapha, AIAA; O'Toole, TR	1
Ausseil, J; Cleren, C; Daher, I; Daumas, S; Dourmap, N; El Mestikawy, S; Gomila, C; Gonzalez, B; Le Dieu-Lugon, B; Lecuyer, M; Leroux, P; Leroux-Nicollet, I; Marret, S; Ramet, L; Roy, V	1
Beccano-Kelly, DA; Bergeron, S; Cataldi, S; Farrer, MJ; Fox, J; Kadgien, CA; Khinda, J; Kuhlmann, N; MacIsaac, SE; Melrose, H; Milnerwood, AJ; Mitchell, E; Paschall, SA; Tatarnikov, I; Volta, M	1
Brodsky, VY; Butorina, NN; Dubovaya, TK; Lazarev Konchenko, DS; Malchenko, LA; Zvezdina, ND	1
Asch, RH; Lindquist, DM; McNamara, RK; Schurdak, JD	1
Davydova, TV; Gruden, MA; Kudrin, VS; Morozova-Roche, LA; Narkevich, VB; Sewell, RDE; Wang, C	1
Ferrari, F; Gorini, A; Hoyer, S; Villa, RF	1
Ahmari, SE; Amara, SG; Ingram, SL; Underhill, SM; Veenstra-VanderWeele, J	1
Ampatzis, K; Bertuzzi, M; Chang, W	1
Bahous, RH; Bedell, BJ; Caudill, MA; Cosín-Tomás, M; Deng, L; Ho, MK; Kaliman, P; Leclerc, D; Malysheva, O; Pallàs, M; Rozen, R	1
Bonaparte, TP; Cavalcante, DT; Costa, FGP; de Vargas Júnior, JG; Lima, MR; Melo, TS; Oliveira, LC; Silva, JHV; Vieira, DVG	1
Cha, MY; Jang, Y; Jeon, SG; Jung, ES; Kim, KS; Kim, W; Lopes, C; Mook-Jung, I; Moon, M	1
Cao, P; Fang, Y; Huang, Y; Lyu, J; Shen, Y; Zhang, J	1
Burger, C; Gimse, KE; O'Riordan, K	1
Jia, L; Liu, B; Ma, J; Qi, X; Shan, Y; Wang, H; Wu, W; Zhou, H	1
Carlquist, J; Davis, B; Fitzpatrick, JAJ; Gantz, JA; Hirose, K; Kallogjeri, D; Kim, KX; Li, SZ; Ohlemiller, KK; Payne, S; Rutherford, MA; V-Ghaffari, B; Yang-Hood, A	1
Buck, A; Gietl, A; Henning, A; Hock, C; Kirchner, T; Leh, SE; Nitsch, RM; Preti, MG; Pruessmann, KP; Quevenco, FC; Schreiner, SJ; Steininger, SC; Unschuld, PG; van Bergen, JMG; Van De Ville, D; Wyss, M	1
Forester, BP; Harper, DG; Jensen, E; Mellen, EJ; Ravichandran, C; Silveri, M	1
Furuhata, R; Komata, Y; Morioka, H; Nishio, R; Takeda, A; Tamano, H	1
Ge, R; Greenway, K; Laule, C; MacMillan, EL; Sporn, L; Vila-Rodriguez, F	1
Bolo, NR; Fried, PJ; Pascual-Leone, A	1
Chen, X; Ji, W; Lei, H; Mao, L; Zhang, H; Zou, Y	1
Guo, X; Han, D; He, J; Li, Y; Li, Z; Liu, H; Liu, T; Manyande, A; Tian, X; Wang, J; Xiang, H; Xu, F; Yang, N	1
Liu, H; Wu, J; Zhang, X	1
Catlow, BJ; Hardy, NF; Jimenez, DV; Manji, HK; Martinowich, K; McKay, RD; Paredes, D; Schloesser, RJ	1
Gallinat, J; Hädel, S; Rapp, M; Schubert, F; Wirth, C	1
Blumenthal, H; Dermiki, M; Gosney, MA; Kennedy, OB; Methven, L; Mottram, DS; Mounayar, R; Scott, J; Suwankanit, C	1
Moser, T; Predoehl, F; Starr, A	1
Baloh, RH; Bouitbir, J; Dupuis, L; Eschbach, J; Fergani, A; Geny, B; Harms, MB; Larmet, Y; Loeffler, JP; Ludolph, AC; Marion, V; Messadeq, N; René, F; Schlagowski, AI; Shy, ME; Sinniger, J; Weydt, P; Zoll, J	1
Klein, J; Koch, KA; Schwarzkopf, TM	1
De Beaumont, L; Henry, LC; Lassonde, M; Poirier, J; Théoret, H; Tremblay, S	1
Goji, A; Harada, M; Ito, H; Kagami, S; Kurosawa, K; Miyazaki, M; Mori, K; Mori, T	1
Kluijtmans, LA; Metaxas, A; Timmer, NM; van Berckel, BN; van der Stelt, I; Verbeek, MM	1
Balayssac, S; Déjean, S; Francés, B; Gilard, V; Halley, H; Lalande, J; Lassalle, JM; Malet-Martino, M; Martino, R	1
Ferrari, F; Gorini, A; Villa, RF	2
Adlard, PA; Bray, L; Bush, AI; Cherny, RA; Doble, P; Finkelstein, DI; Gunawan, L; Hare, D; Lear, J; Sedjahtera, A	1
Bäckman, L; Bertram, L; Heekeren, HR; Li, SC; Lindenberger, U; Nagel, IE; Nietfeld, W; Papenberg, G; Schjeide, BM; Schröder, J	1
Brooks, WM; Choi, IY; Hui, D; Lee, P; Michaelis, EK; Wang, WT; Wang, X	1
Brooks, WM; Choi, IY; Harris, JL; Lee, P; Swerdlow, RH; Yeh, HW	1
Do, KQ; Duarte, JM; Gruetter, R	1
Al-Yahya, AA; Hafez, MM; Hui, D; Michaelis, EK; Pal, R; Patel, ND; Sayed-Ahmed, MM; Wang, X	1
Brandão, R; Dalmolin, L; de Freitas, ML; Leite, MR; Marcondes Sari, MH; Oliveira, LP; Zeni, G	1
Kaliszewska, A; Kossut, M; Lehner, M; Liguz-Lecznar, M; Sobolewska, A; Zakrzewska, R	1
Bellot, A; Bosch-Morató, M; Guivernau, B; Muñoz, FJ; Tajes, M; Valls-Comamala, V	1
Coman, D; Hyder, F; Jiang, L; Lin, AL; Rothman, DL	1
Bramwell, RC; Donato, AJ; Enz, RA; Hart, CR; Hazra, S; Henson, GD; Layec, G; Lesniewski, LA; Morgan, RG; Reihl, KD; Richardson, RS; Trinity, JD; Walker, AE	1
do Carmo, LG; Hsu, YT; Nantes, IL; Smaili, SS; Ureshino, RP; Yokomizo, CH	1
Lalo, U; Pankratov, Y; Rasooli-Nejad, S	1
Bresciani, G; Cechella, JL; da Rocha, JT; Dobrachinski, F; Gai, BM; Leite, MR; Royes, LF; Soares, FA; Zeni, G	1
Bensalem-Owen, M; Davis, VA; Deel, ME; Gerhardt, GA; Huettl, P; Pomerleau, F; Slevin, J; Stephens, ML; Williamson, A	1
Abdel-Aziz, K; Altmann, DR; Ciccarelli, O; Solanky, BS; Thompson, AJ; Wheeler-Kingshott, CA; Yiannakas, MC	1
Calakos, K; Dumitriu, D; Grossman, YS; Jannetty, SK; Janssen, WG; Lambert, HK; McEwen, BS; Morrison, JH; Pereira, AC; Waldman, R	1
Boger, HA; Farrand, AQ; Gregory, RA; Helke, KL; Scofield, MD	1
Gu, H; Guan, H; Lao, J; Li, K; Liu, Y; Wang, W; Zhang, G	1
Xu-Friedman, MA; Yang, Y	1
Cohen-Gilbert, JE; Crowley, DJ; Jensen, JE; Rosso, IM; Silveri, MM; Sneider, JT	1
Jayasena, DD; Jo, C; Jung, S; Kim, HJ; Nam, KC; Yong, HI	1
Gong, QY; Quan, H; Sun, HQ; Tan, QY; Tan, ZJ; Xing, HY; Yang, ZY; Yue, Q	1
Buchert, R; Gallinat, J; Gleich, T; Kühn, S; Lorenz, RC; Schlagenhauf, F	1
Cryan, JF; Glennon, J; Moloney, RD; O'Connor, RM; Vlachou, S	1
Bellaver, B; Quincozes-Santos, A; Raupp, GS; Souza, DG; Souza, DO	1
Akishita, M; Ogawa, S; Ota, H; Ouchi, Y	1
Jing, Y; Leitch, B; Liu, P	1
Arnold, JC; Salvatore, MF	1
Abe, T; Harada, M; Izumi, Y; Kaji, R; Sako, W	1
Albrecht, A; Brück, W; Çalışkan, G; Heinemann, U; Ivens, S; Papageorgiou, IE; Richter-Levin, G; Saiepour, N; Stork, O	1
Barker, PB; Brandt, AS; Churchill, G; Edden, RA; Harris, AD; Hua, J; Lim, IA; Margolis, RL; Pradhan, S; Ross, CA; Unschuld, PG; van Zijl, PC	1
Blennow, K; Bruno, D; Hashimoto, K; Marmar, CR; Nierenberg, J; Pomara, N; Zetterberg, H	1
Davidson, RL; Gray, JD; Kogan, JF; McEwen, BS; Morrison, JH; Okamoto, M; Pereira, AC; Rubin, TG	1
Bartke, A; Boger, HA; Fitzgerald, PJ; Hascup, ER; Hascup, KN; Kopchick, JJ; Lynn, MK; Randall, S	1
Hachem, LD; Mothe, AJ; Tator, CH	1
Bachurin, SO; Efimova, AD; Grigoriev, VV; Myasoedov, NF; Shevchenko, VP; Ustyugov, AA	1
Catanese, A; Gabaglio, M; Grilli, M; Marchi, M; Parolaro, D; Pittaluga, A; Prini, P; Rubino, T; Zamberletti, E	1
Barbosa, RM; Dias, C; Ferreiro, E; Laranjinha, J; Ledo, A; Lourenço, CF	1
Chen, H; Chiappelli, J; Du, X; Gaston, FE; Hong, LE; Kochunov, P; Korenic, SA; McMahon, RP; Ndubuizu, N; Rowland, LM; Savransky, A; Wang, DJ; Wijtenburg, SA; Wright, SN	1
Bellaver, B; Bobermin, LD; Quincozes-Santos, A; Souza, DG; Souza, DO	1
Bruno, F; Canterini, S; Caporali, P; Dragotto, J; Erickson, RP; Fiorenza, MT; Mangia, F; Palladino, G; Petrosini, L	1
Kanamatsu, T; Kohsaka, S; Koshimoto, M; Nakajima, K	1
Du, H; Gauba, E; Guo, L	1
Diaz, MR; Przybysz, KR; Werner, DF	1
Baranovičová, E; Bittšanský, M; Čierny, D; Hnilicová, P; Kantorová, E; Kurča, E; Nosáľ, V; Poláček, H; Sivák, Š; Zeleňák, K	1
Barr, MS; Blumberger, DM; Cash, RF; Chen, R; Daskalakis, ZJ; Farzan, F; Noda, Y; Rajji, TK; Zomorrodi, R	1
Collie, ND; Gupta, N; Jing, Y; Liu, P; Smith, PF; Zhang, H	1
Davydova, TV; Fomina, VG; Gruden, MA; Morozova-Roche, LA; Sewell, RD; Vetrile, LA	1
Jiang, ZZ; Liu, Y; Shang, J; Wang, S; Wang, W; Zhang, LY; Zhang, Z	1
Bogen, IL; Hvalby, O; Jensen, V; Walaas, SI	1
Etgen, AM; Neal-Perry, GS; Shu, J; Zeevalk, GD	1
Adjan, V; Centers, A; Jennes, L	1
Carbone, S; Cardoso, N; Moguilevsky, J; Ponzo, O; Reynoso, R; Scacchi, P; Szwarcfarb, B	1
Abdel-tawab, AM; Amer, MS; El-banouby, MH; El-faramawy, YA; Mortagy, AK; Sergeev, P	1
Avilas, M; Bickford, PC; Cartford, MC; Catlow, BJ; George, A; Paredes, DA; Samec, A; Schlunck, A; Small, B	1
Lebida, K; Mozrzymas, JW; Wójtowicz, T	1
Brewer, GJ; Jones, TT	1
Chalisova, NI; Zakutskii, AN	1
Fleming, R; Li, Q; Madison, RD; Swartzwelder, HS; Wilson, WA; Yan, H	1
Franzoso, G; Liu, B; Neufeld, AH; Papa, S; Suyeoka, G	1
Ahn, SC; Hong, SH; Kim, MJ	1
Kafitz, KW; Kelly, T; Roderigo, C; Rose, CR	1
Behl, C; Hajieva, P; Kuhlmann, C; Luhmann, HJ	1
Boix, J; Felipo, V; Guerri, C; Pascual, M	1
Alkon, DL; Cui, C; Xu, C	1
Estrada-Sánchez, AM; Massieu, L; Montiel, T; Segovia, J	1
Barker, PB; Bibat, G; Farage, L; Horská, A; Kaufmann, WE; Nagae, LM; Naidu, S	1
Aliaga, E; Bonansco, C; Fuenzalida, M; Olivares, V; Roncagliolo, M	1
Andersson, D; Andersson, M; Chergui, K; Egecioglu, E; Emilsson, L; Fejgin, K; Fredriksson, A; Fredriksson, R; Hanse, E; Kullander, K; Lagerström, MC; Långström, B; Lindhe, O; Nordenankar, K; Roman, E; Schiöth, HB; Strandberg, J; Svensson, L; Wallén-Mackenzie, A; Wass, C	1
Gao, WJ; Wang, HX	1
Oja, SS; Saransaari, P	3
Ali, C; Boyer, O; Calbo, S; Catteau, J; Laudenbach, V; Launay, S; Legros, H; Leroux, P; Marcou-Labarre, A; Marret, S; Roussel, BD; Vivien, D	1
Hashimoto, K; Kano, M; Kawata, S; Tanimura, A	1
Gorini, A; Hoyer, S; Villa, RF	2
Dringenberg, HC; Hogsden, JL	1
Amoroso, S; Antonelli, T; Beggiato, S; Cassano, T; Cuomo, V; Ferraro, L; Gaetani, S; Tanganelli, S; Tomasini, MC	1
Gerhardt, GA; Huettl, P; Pomerleau, F; Quintero, JE; Stephens, ML	1
Blumenthal, TD; Liu, C; Lyall, A; Swanson, J; Turner, CP	1
Cengiz, N; Guneser, R; Him, A; Oztürk, G	1
Evrard, A; Ropert, N	1
Héja, L; Kardos, J; Lasztóczi, B; Nyitrai, G	1
Jing, Y; Liu, P; Zhang, H	1
Abdalla, FM; Bertoncini, CR; Fernandes, MJ; Hsu, YT; Lopes, GS; Porto, CS; Smaili, SS; Ureshino, RP	1
Behar, KL; Boumezbeur, F; Cline, GW; de Graaf, RA; Mason, GF; Petersen, KF; Rothman, DL; Shulman, GI	1
Andrade, C; Guma, FT; Heimfarth, L; Lacerda, BA; Loureiro, SO; Pelaez, Pde L; Pessoa-Pureur, R; Santos, NG; Scherer, EB; Soska, A; Tagliari, B; Vidal, LF; Wyse, AT	1
Bérubé-Carrière, N; Dal Bo, G; Descarries, L; Lévesque, D; Riad, M; Trudeau, LE	1
Elssner-Beyer, B; Gottmann, K; Schubert, D; Walz, C	1
Constantin, S; Herbison, AE; Jasoni, CL; Wadas, B	1
Castillo, A; Fernández-Ruiz, J; Martinez-Orgado, J; Romero, J; Tolón, MR	1
Blesch, A; Bonner, JF; Fischer, I; Neuhuber, B	1
Kardos, J; Lasztóczi, B; Nyitrai, G	1
Battu, CE; de Assis, AM; Farina, M; Gonçalves, CA; Hansen, F; Hoefel, AL; Longoni, A; Perry, ML; Rieger, DK; Schmidt, B; Sordi, F; Souza, DO	1
Bradford, J; Li, S; Li, XJ; Roberts, M; Shin, JY; Wang, CE	1
Darra, E; Ebner, FH; Mariotto, S; Shoji, K; Suzuki, H	1
Dierckx, RA; Elsinga, PH; Ishiwata, K; Luiten, PG; Nijholt, IM; Ramakrishnan, NK; Rybczynska, AA; van Waarde, A	1
Bossu, JL; Doussau, F; Dupont, JL; Lonchamp, E; Poulain, B; Shin, HS	1
Bell, JD; Frost, GS; Goldstone, AP; Hankir, M; Herlihy, AH; Kuo, YT; Parkinson, JR; So, PW; Wasserfall, C; Yu, WS	1
Mattsson, P; Raininko, R	1
Brailoiu, E; Churchill, GC; Dickinson, GD; Patel, S	1
Brann, DW; De Sevilla, L; Khan, M; Mahesh, VB	1
Capo, TR; Carlson, SL; Fieber, LA; Schmale, MC	1
Das, M; Edwards, D; Hickman, JJ; Molnar, P	1
Brown, MN; Mathews, GC	1
Billard, JM; Champeil-Potokar, G; Denis, I; Dutar, P; Grintal, B; Jouvenceau, A; Kollen, M; Potier, B; Rivière, S; Sinet, PM	1
Bath, KG; Chao, MV; Dagar, K; Lee, FS; Ninan, I; Perez-Castro, R; Plummer, MR	1
Devaraj, R; Ganesalingam, GS; Liu, P; Smith, PF; Zhang, H	1
Attwell, D; Haglerød, C; Madry, C	1
Baig, I; Guttmann, RP; Levine, H; Mohmmad Abdul, H; Norris, CM	1
Kawai, M; Sasano, T; Satoh-Kuriwada, S; Sekine-Hayakawa, Y; Shoji, N; Uneyama, H	1
McCarthy, MM	1
Burdakov, D; Fugger, L; Jensen, LT; Karnani, MM; Venner, A	1
Takeda, A	1
Chow, VW; Gleichmann, M; Mattson, MP	1
Bannai, S; Beck, H; Conrad, M; De Bundel, D; Fernando, R; Kim, SW; Kobayashi, S; Massie, A; Michotte, Y; Plesnila, N; Sato, H; Schallier, A; Smolders, I; Vermoesen, K	1
Boyko, M; Gruenbaum, BF; Gruenbaum, SE; Klin, Y; Mohar, B; Ohayon, S; Shaked, G; Shapira, Y; Sheiner, E; Teichberg, VI; Zlotnik, A	1
Lalo, U; North, RA; Palygin, O; Pankratov, Y; Verkhratsky, A	1
De Deyn, PP; Loyens, E; Massie, A; Michotte, A; Michotte, Y; Schallier, A; Smolders, I; Van Dam, D	1
Cheng, D; Cheng, Y; Jiang, Y; Lu, H; Pang, W; Yan, X; Yang, H	1
Angara, B; Gvilia, I; McGinty, D; Suntsova, N; Szymusiak, R	1
Bartke, A; Das, SR; Kronemann, D; Magnusson, KR; Patrylo, PR	1
Farooqui, AA; Frisardi, V; Panza, F	1
Camarini, R; Carrara-Nascimento, PF; Griffin, WC; Olive, MF; Pastrello, DM	1
Agostinho, PM; Canas, PM; Costenla, AR; Cunha, RA; de Mendonça, A; Diógenes, MJ; Maroco, J; Nogueira, C; Ribeiro, JA; Rodrigues, RJ	1
Chen, L; Luo, B; Su, YY; Wang, HT; Wu, SH	1
Behar, KL; De Feyter, HM; de Graaf, RA; Mason, GF; Rothman, DL	1
Chen, X; Fang, F; Huang, T; Luddy, JS; Lue, LF; Yan, SS	1
Haroutunian, V; McCullumsmith, RE; Meador-Woodruff, JH; Shan, D	1
Burton, CL; Fletcher, PJ	1
Andersen, ML; de Souza, L; Lopes, GS; Sinigaglia-Coimbra, R; Smaili, SS; Tufik, S; Ureshino, RP	1
Huppé-Gourgues, F; O'Donnell, P	1
Fornander, J; Landin-Olsson, M; Ossiansson, B; Petersson, C; Thunander, M; Törn, C	1
Giaume, C; Orellana, JA; Sáez, JC; von Bernhardi, R	1
Gerhardt, GA; Onifer, SM; Quintero, JE	1
Cai, Q; Chen, SQ; Shen, YY; Teng, GJ; Wang, PJ; Zang, FC; Zhang, W	1
Beaufrère, AM; Bielicki, G; Meynial-Denis, D; Mignon, M; Mirand, PP; Renou, JP	1
Auger, C; Charles, AL; Dal-Ros, S; Geny, B; Keller, N; Metzger, D; Meyer, A; Ramamoorthy, TG; Schini-Kerth, V; Zoll, J	1
Jinno, S; Yamada, J	1
Caumo, W; Dalmaz, C; Fontella, FU; Laste, G; Nonose, Y; Rozisky, JR; Torres, IL; Vendite, D	1
Giusto, NM; Mateos, MV; Salvador, GA	1
Hertz, L; Li, B; Peng, L	1
Ji, C; Jia, X; Liu, W; Qu, X; Wang, H; Wang, Y; Wu, A; Xie, Z; Xu, C; Xu, J; Xu, Z; Yue, Y	1
Chanraud, S; Gu, M; Mayer, D; Pfefferbaum, A; Rohlfing, T; Sullivan, EV; Zahr, NM	1
Boer, VO; Hilleke E, HP; Klomp, DW; Luijten, PR; Mandl, RC; Marsman, A; van den Heuvel, MP; Wijnen, JP	1
Grosche, A; Reichenbach, A	1
Chen, M; Han, X; Lovatt, D; McConnell, E; Nedergaard, M; Pare, JF; Peng, W; Smith, Y; Sun, W; Xu, Q	1
Horita, DA; Kleven, GA; Morgan, JJ; Olson, J; Ronca, AE; Tulbert, CD	1
Brambrink, AM; Guerguerian, AM; Huganir, RL; Martin, LJ; Traystman, RJ	1
Behrens, PF; Franz, P; Landwehrmeyer, GB; Lindenberg, KS; Woodman, B	1
DiGregorio, DA; Nusser, Z; Silver, RA	1
Brown, KM; Wolfe, BB; Wrathall, JR; Yasuda, RP	1
Dias, RD; Gonçalves, CA; Gonçalves, D; Gottfried, C; Moriguchi, E; Souza, DO; Tramontina, F; Wofchuk, ST	1
Gulyaeva, NV; Kudryashov, IE; Kudryashova, I; Yakovlev, AA	1
Warren, RA; Zhang, L	1
Dzubay, JA; Otis, TS	1
Gil Loyzaga, PE	1
Hirose, S; Ito, KI; Kaneko, S; Murakami, T; Okada, M; Wakui, M; Zhu, G	1
Del Vecchio, R; Gold, L; Jolas, T; Priestley, T; Wong, G; Zhang, Q; Zhang, XS	1
Brusque, AM; Dahm, KC; Farina, M; Frizzo, ME; Rocha, JB; Schwalm, FD; Souza, DO; Zeni, G	1
Brewer, GJ; Patel, JR	1
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KRZALIC, L; MIHAILOVIC, L	1
OSBORNE-WHITE, WS; RUSSELL, GR; SMITH, RM	1
HAMILTON, RE; PILGERAM, LO	1
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García-Verdugo, JM; Mora, F; Segovia, G; Yagüe, AG	1
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Murphy, S; Sanderson, C	1
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Hambley, JW; Rogers, LJ	1
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Müller, WE; Scheuer, K; Stoll, S	1
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Garaschuk, O; Kovalchuk, Yu; Krishtal, O	1
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Kornhuber, J; Kornhuber, ME; Retz, W; Riederer, P	1
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Mora, F; Porras, A	1
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Holmes, GL; Hori, A; Liu, Z; Sarkisian, MR; Stafstrom, CE; Tandon, P; Yang, Y	1
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Khyentse, MD; Rogers, LJ	1
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Davis, AM; Herbison, AE; McCarthy, MM; Selmanoff, M; Ward, SC	1
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Hornung, JP; Porter, LL; Rizzo, E	1
Fannin, SW; Hassan, MO; Hoppel, CL; Lesnefsky, EJ; Slabe, TJ	1
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Horrobin, DF; Lynch, MA; Martin, DS; McGahon, BM	1
Brager, DH; McCarthy, MM; Sickel, MJ	1
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Aamodt, SM; Constantine-Paton, M; Shi, J; Townsend, M	1
Ishida, A; Johnston, MV; Lange, MS; Trescher, WH	1
Bates, GP; Brundin, P; Castilho, RF; Hansson, O; Korhonen, L; Lindholm, D	1
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Stavale, JN; Villares, JC	1
Farris, SM; Sinakevitch, I; Strausfeld, NJ	1
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Gottmann, K; Plitzko, D; Rumpel, S	1
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Bandyopadhyay, BC; Chakrabarti, L; Poddar, MK	1
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Gorter, JA; Mirmiran, M; Veerman, M	1
Cohen, SA; Müller, WE	1
Barr, GA; Tive, LA	1
Christensen, H; Fonnum, F	2
Lanius, RA; Shaw, C	1
Scarth, BA; Shaw, C	1
Jankásková, B; Lisý, V; Stastný, F	1
Banay-Schwartz, M; Lajtha, A; Palkovits, M	1
Foley, TD; Rhoads, DE	1
Dawson, R; Wallace, DR	1
Martin, D; McNamara, JO; Nadler, JV	1
Carpenter, MK; Miledi, R; Parker, I	2
Hestrin, S	1
East, SJ; Garthwaite, J; Southam, E	1
Jani, MS; Katyare, SS; Telang, SD	1
Kitamura, Y; Nomura, Y	1
Ball, WD; Hand, AR; Mirels, L; Moreira, JE	1
Dickson, AC; Koeppen, AH; Riley, KM	1
Alesiani, M; Cherici, G; Moroni, F; Pellegrini-Giampietro, DE	1
Bilkey, DK; Heynen, AJ	1
Auer, RN	1
Daw, N; Gordon, B; Parkinson, D	1
Gallagher, M; Hong, JS; Hudson, PM; Mundy, WR; Thai, L; Tilson, HA; Zhang, WQ	1
Barres, BA; Chun, LL; Corey, DP; Koroshetz, WJ	1
Erdö, SL; Wolff, JR	1
Gelhard, RE; Insel, TR; Miller, LP	1
Arnerić, SP; Caspary, DM; Lawhorn Armour, BA; Pippin, J; Raza, A	1
Bos, KD; Bruyn, GW; Ferrari, MD; Malessy, MJ; Odink, J	1
Bettler, B; Borgmeyer, U; Boulter, J; Deneris, ES; Heinemann, S; Hermans-Borgmeyer, I; Hollmann, M; Moll, C; O'Shea-Greenfield, A	1
Gilad, GM; Gilad, VH; Tizabi, Y	1
Bowen, DM; Francis, PT; Lowe, SL; Pangalos, MN; Procter, AW; Steele, JE	1
Sapolsky, RM	1
Olney, JW	1
Eybalin, M; Lenoir, M; Puel, JL; Pujol, R; Rebillard, G; Recasens, M	1
Kim, SY; Kish, PE; Ueda, T	1
Eriksdotter-Nilsson, M; Gerhardt, G; Granholm, AC; Hoffer, B; Olson, L; Seiger, A	1
Kouvelas, ED; Michalodimitrakis, M; Mitsacos, A; Plaitakis, A; Tsiotos, P; Voukelatou, G	1
Bode-Greuel, KM; Singer, W	1
Bear, MF; Bowen, WD; Dudek, SM	1
Ben-Ari, Y; Represa, A; Tremblay, E	1
Guiramand, J; Recasens, M; Sassetti, I	1
Helgason, CD; Wood, JD	1
Cotman, CW; Peterson, C	1
Bear, MF; Dudek, SM	1
Cox, JA; Henneberry, RC; Lysko, PG; Novelli, A	1
Garthwaite, J	1
Ito, M; Matsumoto, H	1
Edamura, M; Ito, M; Kikuchi, S; Matsumoto, H	1
Hansson, E	1
Dutar, P; Jobert, A; Lamour, Y	2
Arai, H; Iizuka, R; Kanazawa, I; Kosaka, K; Muramoto, O; Sasaki, H	1
Schmidt, W; Wolf, G	1
Aragonés, MD; Catalán, RE; Godoy, JE; Martínez, AM; Miguel, BG; Robles, A	1
Beal, MF; Bird, ED; Ellison, DW; Martin, JB; Mazurek, MF	1
Bezverkhnaia, IS; Kuprash, LP; Oranskaia, SA; Zaika, MU; Zapadniuk, VI	1
Lehne, RA; Rall, TW	1
Greenamyre, T; Hudson, C; Johnston, MV; Penney, JB; Silverstein, FS; Young, AB	1
Gnaedinger, JM; Miller, JC; Rapoport, SI	1
Arlis, S; Balm, M; Coyle, JT; Drucker, H; Zaczek, R	1
Nelson, DO	1
Freeman, GB; Gibson, GE	1
Aprikyan, GV; Gekchyan, KG	1
Hertz, L; Hogstad, S; Kvamme, E; Schousboe, A; Svenneby, G; Torgner, IA	1
Agrawal, YP; Vanha-Perttula, T	1
Angelatou, F; Goulas, V; Kouvelas, ED; Mitsacos, A	1
Ben-Ari, Y; Charriaut-Marlangue, C; Represa, A; Roisin, MP; Tremblay, E	1

Reviews

33 review(s) available for glutamic acid and Aging

Article	Year
The far-reaching HAND of cART: cART effects on astrocytes. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2021, Volume: 16, Issue:1 Topics: Aging; AIDS Dementia Complex; Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Astrocytes; Calcium; Cellular Senescence; Central Nervous System; Glucose; Glutamic Acid; Glutamine; HIV Infections; HIV-1; Humans; Mitochondria; Neurocognitive Disorders; Oxidative Stress; Phenotype; Prevalence; Rats	2021
d-serine in physiological and pathological brain aging. Biochimica et biophysica acta. Proteins and proteomics, 2021, Volume: 1869, Issue:1 Topics: Aging; Alzheimer Disease; Animals; Astrocytes; Cognition; Gene Expression; Glucose; Glutamic Acid; Hippocampus; Humans; Memory; Neuronal Plasticity; Neurons; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Serine	2021
The Regulation of Astrocytic Glutamate Transporters in Health and Neurodegenerative Diseases. International journal of molecular sciences, 2020, Dec-17, Volume: 21, Issue:24 Topics: Aging; Animals; Astrocytes; Biological Transport; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamic Acid; Humans; Neurodegenerative Diseases; Neurons; Receptors, Notch; Signal Transduction	2020
Review of hair cell synapse defects in sensorineural hearing impairment. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2013, Volume: 34, Issue:6 Topics: Aging; Animals; Deafness; Glutamic Acid; Hair Cells, Auditory; Hearing Loss; Hearing Loss, Noise-Induced; Hearing Loss, Sensorineural; Humans; Membrane Proteins; Mice; Synapses; Vesicular Glutamate Transport Proteins	2013
The structure and function of actin cytoskeleton in mature glutamatergic dendritic spines. Brain research, 2014, Jul-21, Volume: 1573 Topics: Actin Cytoskeleton; Aging; Animals; Brain; Dendritic Spines; Glutamic Acid; Humans; Neuronal Plasticity	2014
Short- and long-term consequences of prenatal exposure to the cannabinoid agonist WIN55,212-2 on rat glutamate transmission and cognitive functions. Journal of neural transmission (Vienna, Austria : 1996), 2009, Volume: 116, Issue:8 Topics: Aging; Animals; Benzoxazines; Cannabinoid Receptor Agonists; Cannabinoids; Cerebral Cortex; Cognition; Emotions; Female; Glutamic Acid; Hippocampus; Humans; Learning; Morpholines; Naphthalenes; Neurons; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Synaptic Transmission; Time Factors	2009
The cholinergic system, sigma-1 receptors and cognition. Behavioural brain research, 2011, Aug-10, Volume: 221, Issue:2 Topics: Acetylcholine; Aging; Animals; Brain; Calcium; Cell Differentiation; Cholinergic Fibers; Cognition; Disease Models, Animal; Glutamic Acid; Humans; N-Methylaspartate; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Psychotropic Drugs; Receptors, sigma; Sigma-1 Receptor	2011
What can development teach us about menopause? Brain research, 2011, Mar-16, Volume: 1379 Topics: Aging; Animals; Brain; Estrogens; Female; Glutamic Acid; Humans; Menopause; Neurogenesis; Sex Differentiation	2011
Zinc signaling in the hippocampus and its relation to pathogenesis of depression. Molecular neurobiology, 2011, Volume: 44, Issue:2 Topics: Aging; Animals; Depression; Glutamic Acid; Hippocampus; Homeostasis; Humans; Hypothalamo-Hypophyseal System; Long-Term Potentiation; Mossy Fibers, Hippocampal; Signal Transduction; Stress, Physiological; Zinc	2011
Homeostatic disinhibition in the aging brain and Alzheimer's disease. Journal of Alzheimer's disease : JAD, 2011, Volume: 24, Issue:1 Topics: Aging; Alzheimer Disease; Animals; Brain; Glutamic Acid; Homeostasis; Humans; Neural Inhibition; Synaptic Transmission	2011
Late-life depression and Alzheimer's disease: the glutamatergic system inside of this mirror relationship. Brain research reviews, 2011, Jun-24, Volume: 67, Issue:1-2 Topics: Aged; Aging; Alzheimer Disease; Animals; Comorbidity; Depressive Disorder; Glutamic Acid; Humans	2011
13C MRS studies of neuroenergetics and neurotransmitter cycling in humans. NMR in biomedicine, 2011, Volume: 24, Issue:8 Topics: Aging; Alzheimer Disease; Animals; Brain; Carbon Isotopes; Citric Acid Cycle; Energy Metabolism; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Neurons; Neurotransmitter Agents	2011
Glial hemichannels and their involvement in aging and neurodegenerative diseases. Reviews in the neurosciences, 2012, Jan-26, Volume: 23, Issue:2 Topics: Adenosine Triphosphate; Aging; Astrocytes; Calcium; Cannabinoids; Central Nervous System; Connexin 43; Connexins; Dinoprostone; Glucose; Glutamic Acid; Humans; Inflammation; Interleukin-1beta; Ion Channels; NAD; Nerve Degeneration; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Oligodendroglia; Signal Transduction; Tumor Necrosis Factor-alpha	2012
[Psychotropic drug treatment in dementia disorders]. Deutsche medizinische Wochenschrift (1946), 2004, Jun-18, Volume: 129, Issue:25-26 Topics: Aged; Aged, 80 and over; Aging; Antidepressive Agents; Cholinesterase Inhibitors; Dementia; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glutamic Acid; Humans; Male; Memantine; Psychotropic Drugs; Receptors, N-Methyl-D-Aspartate; Treatment Outcome	2004
Glutamate-dopamine-GABA interactions in the aging basal ganglia. Brain research reviews, 2008, Volume: 58, Issue:2 Topics: Age Factors; Aging; Animals; Basal Ganglia; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Models, Biological; Motor Activity; Neural Pathways; Neurons	2008
The regulation of dendritic arbor development and plasticity by glutamatergic synaptic input: a review of the synaptotrophic hypothesis. The Journal of physiology, 2008, Mar-15, Volume: 586, Issue:6 Topics: Aging; Animals; Axons; Dendrites; Glutamic Acid; Humans; Models, Neurological; Neuronal Plasticity; Receptors, Glutamate; Synapses; Synaptic Transmission	2008
Glutamate: its role in learning, memory, and the aging brain. Psychopharmacology, 1993, Volume: 111, Issue:4 Topics: Aging; Animals; Glutamic Acid; Humans; Learning; Memory	1993
Glutamatergic treatment strategies for age-related memory disorders. Life sciences, 1994, Volume: 55, Issue:25-26 Topics: Acetamides; Aging; Animals; Cognition; Cycloserine; Glutamic Acid; Humans; Memory Disorders; N-Methylaspartate; Nootropic Agents; Receptors, N-Methyl-D-Aspartate	1994
Melatonin, hydroxyl radical-mediated oxidative damage, and aging: a hypothesis. Journal of pineal research, 1993, Volume: 14, Issue:4 Topics: Aging; Animals; Calcium; Free Radical Scavengers; Free Radicals; Glutamates; Glutamic Acid; Humans; Hydroxides; Melatonin; Nerve Degeneration	1993
The sodium-calcium exchanger and glutamate-induced calcium loads in aged hippocampal neurons in vitro. Annals of the New York Academy of Sciences, 1996, Apr-15, Volume: 779 Topics: Aging; Animals; Calcium; Carrier Proteins; Cells, Cultured; Glutamic Acid; Hippocampus; N-Methylaspartate; Neurons; Rats; Sodium; Sodium-Calcium Exchanger	1996
Excitatory neurotransmission and sexual differentiation of the brain. Brain research bulletin, 1997, Volume: 44, Issue:4 Topics: Aging; Animals; Brain; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Male; Models, Neurological; Neurons; Neurotransmitter Agents; Sex Characteristics; Synaptic Transmission	1997
Glutamate in schizophrenia: clinical and research implications. Schizophrenia research, 1997, Oct-30, Volume: 27, Issue:2-3 Topics: Aging; Citric Acid Cycle; Dopamine; Glutamic Acid; Humans; Phencyclidine; Receptors, Amino Acid; Receptors, Glutamate; Schizophrenia	1997
Dopamine and N-methyl-D-aspartate receptor interactions in the neostriatum. Developmental neuroscience, 1998, Volume: 20, Issue:1 Topics: Afferent Pathways; Aging; Animals; Calcium; Calcium Channels; Calcium Channels, L-Type; Cerebral Cortex; Cyclic AMP; Dopamine; Dopamine Agents; Embryonic and Fetal Development; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Ion Transport; Models, Neurological; Neostriatum; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Rats; Receptors, Dopamine; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Substantia Nigra; Synaptic Transmission	1998
Age-related impairment in long-term potentiation in hippocampus: a role for the cytokine, interleukin-1 beta? Progress in neurobiology, 1998, Volume: 56, Issue:5 Topics: Aging; Animals; Antioxidants; Arachidonic Acid; Cognition Disorders; Fatty Acids, Unsaturated; Glutamic Acid; Hippocampus; Humans; Interleukin-1; Lipid Peroxidation; Long-Term Potentiation; Membrane Fluidity; Membrane Lipids; Memory Disorders; Models, Neurological; Phospholipases; Phosphorylation; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Rats	1998
[Endogenous interaction of neurotransmitters and aging: studies on the basal ganglia of awake rats]. Anales de la Real Academia Nacional de Medicina, 1999, Volume: 116, Issue:4 Topics: Aging; Animals; Basal Ganglia; Dopamine; Glutamic Acid; Rats; Wakefulness	1999
The function of the cholinergic system in the developing mammalian retina. Progress in brain research, 2001, Volume: 131 Topics: Aging; Animals; Animals, Newborn; Cholinergic Fibers; Electrophysiology; Glutamic Acid; Mammals; Muscarine; Nicotine; Receptors, Neurotransmitter; Retina; Synaptic Transmission	2001
Neural mechanisms underlying the pubertal increase in LHRH release in the rhesus monkey. Trends in endocrinology and metabolism: TEM, 2001, Volume: 12, Issue:8 Topics: Aging; Animals; Brain; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropin-Releasing Hormone; Hypothalamus; Macaca mulatta; Male; Sexual Maturation	2001
Lipoic acid confers protection against oxidative injury in non-neuronal and neuronal tissue. Nutritional neuroscience, 2001, Volume: 4, Issue:6 Topics: Aging; Animals; Antioxidants; Glutamic Acid; Humans; Long-Term Potentiation; Mitochondria; Nervous System Diseases; Neurodegenerative Diseases; Neurons; Oxidative Stress; Reperfusion Injury; Signal Transduction; Thioctic Acid	2001
Plasticity of the hippocampus: adaptation to chronic stress and allostatic load. Annals of the New York Academy of Sciences, 2001, Volume: 933 Topics: Adaptation, Physiological; Adrenal Cortex; Aging; Animals; Atrophy; Brain Ischemia; Chronic Disease; Circadian Rhythm; Dendrites; Dentate Gyrus; Depression; Estrogens; Female; Glucocorticoids; Glutamic Acid; Hippocampus; Humans; Hypothalamo-Hypophyseal System; Male; Memory Disorders; Models, Animal; Neuralgia; Neurons; Pain; Pituitary-Adrenal System; Rats; Restraint, Physical; Seizures; Stress Disorders, Post-Traumatic; Stress, Physiological; Tumor Necrosis Factor-alpha	2001
Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses? Annals of neurology, 1992, Volume: 31, Issue:2 Topics: Aging; Alzheimer Disease; Animals; Brain Diseases; Cell Death; Energy Metabolism; Glutamates; Glutamic Acid; Humans; Huntington Disease; Ion Channel Gating; Mitochondria; Models, Biological; MPTP Poisoning; Nerve Degeneration; Neurons; Neurotoxins; Oxidative Phosphorylation; Parkinson Disease; Parkinson Disease, Secondary; Primates; Rats; Receptors, N-Methyl-D-Aspartate	1992
Clinical correlations of the neurobiological changes of aging. Annales de medecine interne, 1990, Volume: 141 Suppl 1 Topics: Aged; Aging; Alzheimer Disease; Amino Acids; Cerebral Cortex; Depressive Disorder; Energy Metabolism; Glutamates; Glutamic Acid; Humans; Neurons	1990
Glucocorticoids, hippocampal damage and the glutamatergic synapse. Progress in brain research, 1990, Volume: 86 Topics: Aging; Animals; Calcium Channels; Cell Survival; Cognition; Drug Synergism; Energy Metabolism; Glucocorticoids; Glutamates; Glutamic Acid; Hippocampus; Ion Channel Gating; Male; Models, Biological; Neurons; Neurotoxins; Rats; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Stress, Physiological; Synapses	1990
Excitotoxin-mediated neuron death in youth and old age. Progress in brain research, 1990, Volume: 86 Topics: Aging; Alzheimer Disease; Amino Acids; Animals; Aspartic Acid; Brain Diseases, Metabolic; Brain Injuries; Calcium Channels; Cell Survival; Central Nervous System; Central Nervous System Diseases; Food; Food Additives; Glutamates; Glutamic Acid; Humans; Ion Channel Gating; Neurons; Neurotoxins; Rats; Receptors, N-Methyl-D-Aspartate	1990

Trials

5 trial(s) available for glutamic acid and Aging

Article	Year
Supplementation of L-glycine and L-glutamate to Japanese quails from 01 to 36 days of age using the ideal protein concept. Journal of animal physiology and animal nutrition, 2019, Volume: 103, Issue:1 Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Coturnix; Diet; Dietary Proteins; Dietary Supplements; Glutamic Acid; Glycine; Male; Random Allocation	2019
Fibroblast glutamate transport in aging and in AD: correlations with disease severity. Neurobiology of aging, 2005, Volume: 26, Issue:6 Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amino Acid Transport System X-AG; Biological Transport; Cells, Cultured; Excitatory Amino Acid Transporter 1; Female; Fibroblasts; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Male; Middle Aged; Severity of Illness Index; Statistics as Topic; Symporters	2005
Aspartate and glutamate modulation of growth hormone secretion in the pig: possible site of action. Domestic animal endocrinology, 1996, Volume: 13, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Aspartic Acid; Body Weight; Cells, Cultured; Dose-Response Relationship, Drug; Female; Glutamic Acid; Growth Hormone; Growth Hormone-Releasing Hormone; N-Methylaspartate; Ovariectomy; Pituitary Gland, Anterior; Serum Albumin; Swine	1996
Aging alters regional multichemical profile of the human brain: an in vivo 1H-MRS study of young versus middle-aged subjects. Journal of neurochemistry, 2001, Volume: 76, Issue:2 Topics: Adult; Age Factors; Aging; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Female; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Reference Values	2001
Aging alters the multichemical networking profile of the human brain: an in vivo (1)H-MRS study of young versus middle-aged subjects. Journal of neurochemistry, 2001, Volume: 77, Issue:1 Topics: Adult; Aging; Analysis of Variance; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Female; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Net; Organ Specificity	2001

Other Studies

579 other study(ies) available for glutamic acid and Aging

Article	Year
Differential Effects of Human P301L Tau Expression in Young versus Aged Mice. International journal of molecular sciences, 2021, Oct-28, Volume: 22, Issue:21 Topics: Aging; Alzheimer Disease; Animals; Gene Expression; Glutamic Acid; Humans; Male; Maze Learning; Mice; Mice, Transgenic; Mutation; tau Proteins	2021
Effects of Antibodies to Glutamate on Cerebral Expression of the Tnfrsf1A Gene under Conditions of Spatial Amnesia Induced by Proinflammatory Protein S100A9 Fibrils in Aging Mice. Bulletin of experimental biology and medicine, 2021, Volume: 172, Issue:1 Topics: Aging; Amnesia; Animals; Antibodies; Calgranulin B; Cerebellum; Glutamic Acid; Hippocampus; Inflammation; Male; Mice; Mice, Inbred C57BL; Prefrontal Cortex; Receptors, Tumor Necrosis Factor, Type I; Spatial Memory; Spatial Navigation; Tumor Necrosis Factor-alpha	2021
The glutamate/GABA system in the retina of male rats: effects of aging, neurodegeneration, and supplementation with melatonin and antioxidant SkQ1. Biogerontology, 2022, Volume: 23, Issue:5 Topics: Aging; Aminobutyrates; Animals; Antioxidants; Dietary Supplements; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Macular Degeneration; Male; Melatonin; Rats; Rats, Wistar; Retina	2022
Changes in aging-induced kidney dysfunction in mice based on a metabolomics analysis. Frontiers in endocrinology, 2022, Volume: 13 Topics: Aging; Animals; Biomarkers; Citrates; Glutamic Acid; Glutamine; Glyoxylates; Histidine; Kidney; Male; Mice; Nucleotides; Purines; Pyruvates; Renal Insufficiency; Tricarboxylic Acids	2022
Cerebral Expression of the Neuregulin-1 Gene NRG1 during Induced Spatial Memory Impairment and Its Reversal in Aging Mice. Bulletin of experimental biology and medicine, 2022, Volume: 174, Issue:1 Topics: Aging; Amyloidogenic Proteins; Animals; Antibodies; Calgranulin B; Cerebrum; ErbB Receptors; Glutamic Acid; Memory Disorders; Mice; Mice, Inbred C57BL; Neuregulin-1; Spatial Memory	2022
Study on the targeted regulation of Scutellaria baicalensis leaf on glutamine-glutamate metabolism and glutathione synthesis in the liver of d-gal ageing rats. The Journal of pharmacy and pharmacology, 2023, Sep-01, Volume: 75, Issue:9 Topics: Aging; Animals; Glutamic Acid; Glutamine; Glutathione; Liver; NF-E2-Related Factor 2; Plant Leaves; Rats; Scutellaria baicalensis	2023
Glutamate, GABA, and Presynaptic Markers Involved in Neurotransmission Are Differently Affected by Age in Distinct Mouse Brain Regions. ACS chemical neuroscience, 2019, 11-20, Volume: 10, Issue:11 Topics: Aging; Animals; Biomarkers; Blotting, Western; Brain; Brain Chemistry; Female; gamma-Aminobutyric Acid; Glutamic Acid; Mice; Mice, Inbred C57BL; Presynaptic Terminals; Principal Component Analysis; Real-Time Polymerase Chain Reaction; Synaptic Transmission	2019
Alpha-asarone improves cognitive function of aged rats by alleviating neuronal excitotoxicity via GABA Neuropharmacology, 2020, 01-01, Volume: 162 Topics: Aging; Allosteric Regulation; Allylbenzene Derivatives; Amyloid beta-Peptides; Animals; Anisoles; Calcium; Cognition; Glutamic Acid; Hippocampus; Molecular Docking Simulation; Molecular Dynamics Simulation; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Peptide Fragments; Rats; Receptors, GABA-A; Spatial Memory	2020
Age-Related Intraneuronal Aggregation of Amyloid-β in Endosomes, Mitochondria, Autophagosomes, and Lysosomes. Journal of Alzheimer's disease : JAD, 2020, Volume: 73, Issue:1 Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Autophagosomes; Cells, Cultured; Endosomes; Glutamic Acid; Humans; Immunohistochemistry; Lysosomes; Mice; Mice, Transgenic; Mitochondria; Neurons; Particle Size	2020
Candesartan Neuroprotection in Rat Primary Neurons Negatively Correlates with Aging and Senescence: a Transcriptomic Analysis. Molecular neurobiology, 2020, Volume: 57, Issue:3 Topics: Aging; Animals; Benzimidazoles; Biphenyl Compounds; Cellular Senescence; Glutamic Acid; Hippocampus; Neurons; Neuroprotection; Oxidative Stress; Rats; Tetrazoles; Transcriptome	2020
Conditional Single Vector CRISPR/SaCas9 Viruses for Efficient Mutagenesis in the Adult Mouse Nervous System. Cell reports, 2020, 03-24, Volume: 30, Issue:12 Topics: Aging; Animals; Base Sequence; Cell Line; CRISPR-Associated Protein 9; CRISPR-Cas Systems; Dependovirus; DNA Nucleotidyltransferases; GABA Plasma Membrane Transport Proteins; Genetic Vectors; Glutamic Acid; Mice, Inbred C57BL; Mutagenesis; Mutation; Nervous System; Optogenetics; Phenotype	2020
Pre- and post-synaptic roles for DCC in memory consolidation in the adult mouse hippocampus. Molecular brain, 2020, 04-07, Volume: 13, Issue:1 Topics: Aging; Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; DCC Receptor; Dendritic Spines; Gene Deletion; Glutamic Acid; Hippocampus; Memory Consolidation; Mice, Inbred C57BL; Neurons; Pyramidal Cells; Spatial Memory; Synapses	2020
Antibodies to Glutamate Facilitate Spatial Memory Formation in the Morris Water Maze in Aging C57BL/6 mice. Bulletin of experimental biology and medicine, 2020, Volume: 169, Issue:1 Topics: Aging; Animals; Antibodies; Behavior, Animal; Glutamic Acid; Male; Maze Learning; Mice; Mice, Inbred C57BL; Morris Water Maze Test; Spatial Memory	2020
Microglia eLife, 2020, 06-24, Volume: 9 Topics: Aging; Animals; Cytokines; Female; Gene Expression Regulation; Genetic Variation; Genotype; Glutamic Acid; Long-Term Potentiation; Macrophages; Male; Membrane Glycoproteins; Microglia; Rats; Receptors, Immunologic; RNA, Messenger; Tumor Necrosis Factor-alpha	2020
Changes in the intracellular microenvironment in the aging human brain. Neurobiology of aging, 2020, Volume: 95 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Aspartic Acid; Brain; Brain Chemistry; Cellular Microenvironment; Choline; Creatine; Female; Glutamic Acid; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Young Adult	2020
Spectral blueshift of biophotonic activity and transmission in the ageing mouse brain. Brain research, 2020, 12-15, Volume: 1749 Topics: Aging; Animals; Biophysics; Brain; Glutamic Acid; Mice; Synaptic Transmission	2020
Live Animal Imaging and Cell Sorting Methods for Investigating Neurodegeneration in a C. elegans Excitotoxic Necrosis Model. Journal of visualized experiments : JoVE, 2021, 01-22, Issue:167 Topics: Aging; Animal Husbandry; Animals; Apoptosis; Buffers; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Flow Cytometry; Glutamic Acid; Imaging, Three-Dimensional; Mitochondria; Necrosis; Nerve Degeneration; Neurons; Neuroprotection; Neurotoxins; Risk Factors; RNA; Transcriptome	2021
Astrocyte dystrophy in ageing brain parallels impaired synaptic plasticity. Aging cell, 2021, Volume: 20, Issue:3 Topics: Aging; Animals; Astrocytes; Calcium; Cell Membrane; Cell Size; Glutamic Acid; Hippocampus; Long-Term Potentiation; Longevity; Male; Mice, Inbred C57BL; Neuronal Plasticity; Potassium	2021
Neonatal programming with sex hormones: Effect on expression of dopamine D European journal of pharmacology, 2021, Jul-05, Volume: 902 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Animals; Animals, Newborn; Dopamine; Dopamine Agonists; Estradiol; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gonadal Steroid Hormones; Injections; Male; Nucleus Accumbens; Rats, Sprague-Dawley; Receptors, Dopamine D1; Sex Factors; Testosterone Propionate; Time	2021
Delayed Behavioral and Neurochemical Effects of Anti-Glutamate Antibodies in Aging C57BL/6 Mice. Bulletin of experimental biology and medicine, 2021, Volume: 171, Issue:1 Topics: Aging; Animals; Aspartic Acid; Glutamic Acid; Hippocampus; Mice; Mice, Inbred C57BL	2021
Multiple synaptic connections into a single cortical pyramidal cell or interneuron in the anterior cingulate cortex of adult mice. Molecular brain, 2021, 06-03, Volume: 14, Issue:1 Topics: Aging; Animals; Glutamic Acid; Gyrus Cinguli; Interneurons; Kinetics; Male; Mice, Inbred C57BL; Neural Conduction; Pyramidal Cells; Receptors, AMPA; Receptors, Kainic Acid; Synapses; Synaptic Transmission	2021
Early Onset of Age-Related Cataracts in Cystine/Glutamate Antiporter Knockout Mice. Investigative ophthalmology & visual science, 2021, 06-01, Volume: 62, Issue:7 Topics: Aging; Animals; Antiporters; Aqueous Humor; Cataract; Cystine; Glutamic Acid; Lens, Crystalline; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Oxidation-Reduction; Oxidative Stress; Slit Lamp Microscopy	2021
3T hippocampal glutamate-glutamine complex reflects verbal memory decline in aging. Neurobiology of aging, 2017, Volume: 54 Topics: Adult; Aged; Aging; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Memory; Memory Disorders; Verbal Behavior	2017
Region-specific aging of the human brain as evidenced by neurochemical profiles measured noninvasively in the posterior cingulate cortex and the occipital lobe using Neuroscience, 2017, 06-23, Volume: 354 Topics: Aged; Aged, 80 and over; Aging; Ascorbic Acid; Aspartic Acid; Brain Chemistry; Creatine; Dipeptides; Female; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Occipital Lobe; Phosphocreatine; Tritium; Young Adult	2017
Amino acid and acetylcholine chemistry in the central auditory system of young, middle-aged and old rats. Hearing research, 2017, Volume: 350 Topics: Acetylcholine; Age Factors; Aging; Amino Acids; Animals; Aspartic Acid; Auditory Pathways; Brain; Choline O-Acetyltransferase; Crosses, Genetic; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hearing; Male; Presbycusis; Rats, Inbred BN; Rats, Inbred F344	2017
Magnesium Sulfate Prevents Neurochemical and Long-Term Behavioral Consequences of Neonatal Excitotoxic Lesions: Comparison Between Male and Female Mice. Journal of neuropathology and experimental neurology, 2017, Oct-01, Volume: 76, Issue:10 Topics: Aging; Animals; Animals, Newborn; Brain; Calcium Channel Blockers; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Functional Laterality; Gait Disorders, Neurologic; gamma-Aminobutyric Acid; Glutamic Acid; Ibotenic Acid; Longitudinal Studies; Magnesium Sulfate; Male; Mice; Motor Skills; Neurotoxicity Syndromes; Sex Factors; Vesicular Glutamate Transport Protein 1	2017
Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in LRRK2 G2019S knock-in mice. eLife, 2017, 09-20, Volume: 6 Topics: Aging; Animals; Dopamine; Exploratory Behavior; Gene Knock-In Techniques; Glutamic Acid; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutant Proteins; Neurons; Synaptic Transmission	2017
Glutamic Acid as Enhancer of Protein Synthesis Kinetics in Hepatocytes from Old Rats. Biochemistry. Biokhimiia, 2017, Volume: 82, Issue:8 Topics: Aging; Animals; Cell Communication; Cells, Cultured; Cellular Senescence; Glutamic Acid; Glycine; Hepatocytes; Kinetics; Neurons; Protein Biosynthesis; Rats; Rats, Wistar; Signal Transduction	2017
Glutamate homeostasis in the adult rat prefrontal cortex is altered by cortical docosahexaenoic acid accrual during adolescence: An in vivo Psychiatry research. Neuroimaging, 2017, Dec-30, Volume: 270 Topics: Aging; Amino Acid Transport System X-AG; Animals; Astrocytes; Diet; Docosahexaenoic Acids; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Homeostasis; Male; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Rats; Rats, Long-Evans	2017
S100A9 Protein Aggregates Boost Hippocampal Glutamate Modifying Monoaminergic Neurochemistry: A Glutamate Antibody Sensitive Outcome on Alzheimer-like Memory Decline. ACS chemical neuroscience, 2018, 03-21, Volume: 9, Issue:3 Topics: Aging; Alzheimer Disease; Animals; Behavior, Animal; Calgranulin B; Glutamic Acid; Hippocampus; Memory Disorders; Mice; Neurotransmitter Agents; Protein Aggregates; Spatial Memory	2018
Glutamate metabolism in cerebral mitochondria after ischemia and post-ischemic recovery during aging: relationships with brain energy metabolism. Journal of neurochemistry, 2018, Volume: 146, Issue:4 Topics: Aging; Analysis of Variance; Animals; Brain Ischemia; Cerebral Cortex; Electron Transport Complex IV; Energy Metabolism; Glutamate Dehydrogenase; Glutamic Acid; Male; Mitochondria; Rats; Rats, Wistar; Recovery of Function; Synaptosomes; Time Factors	2018
Neuronal excitatory amino acid transporter EAAT3: Emerging functions in health and disease. Neurochemistry international, 2019, Volume: 123 Topics: Age Factors; Aging; Amino Acid Transport System X-AG; Animals; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glutamic Acid; Humans; Neurons	2019
Adult spinal motoneurons change their neurotransmitter phenotype to control locomotion. Proceedings of the National Academy of Sciences of the United States of America, 2018, 10-16, Volume: 115, Issue:42 Topics: Aging; Animals; Behavior, Animal; Glutamic Acid; Locomotion; Motor Neurons; Neuromuscular Junction; Neurotransmitter Agents; Phenotype; Spinal Cord Injuries; Synapses; Zebrafish	2018
Early Manifestations of Brain Aging in Mice Due to Low Dietary Folate and Mild MTHFR Deficiency. Molecular neurobiology, 2019, Volume: 56, Issue:6 Topics: Aging; Amyloid beta-Peptides; Animals; Anxiety; Brain; Cell Survival; Cerebral Cortex; Choline; CpG Islands; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid; Glutamic Acid; Homocystinuria; Liver; Male; Memory Disorders; Memory, Short-Term; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice, Inbred BALB C; Muscle Spasticity; Nerve Growth Factors; Neurons; Phospholipids; Psychotic Disorders; RNA, Messenger; S-Adenosylmethionine; Synaptic Transmission	2019
Nurr1 (NR4A2) regulates Alzheimer's disease-related pathogenesis and cognitive function in the 5XFAD mouse model. Aging cell, 2019, Volume: 18, Issue:1 Topics: Aging; Alzheimer Disease; Amodiaquine; Animals; Brain; Cognition; Disease Models, Animal; Glutamic Acid; Humans; Mice, Inbred C57BL; Mice, Transgenic; Neuroglia; Neurons; Nuclear Receptor Subfamily 4, Group A, Member 2; Postmortem Changes	2019
The age-related changes and differences in energy metabolism and glutamate-glutamine recycling in the d-gal-induced and naturally occurring senescent astrocytes in vitro. Experimental gerontology, 2019, Volume: 118 Topics: Aging; Animals; Astrocytes; Cells, Cultured; Cellular Senescence; Energy Metabolism; Galactose; Glutamic Acid; Glutamine; Glycolysis; Mitochondria; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptors, GABA-B	2019
Effect of Antibodies to Glutamate on Age-Related Memory Changes in C57Bl/6 Mice. Bulletin of experimental biology and medicine, 2019, Volume: 166, Issue:3 Topics: Administration, Intranasal; Aging; Animals; Antibodies; Aspartic Acid; Avoidance Learning; Conditioning, Psychological; Dopamine; Excitatory Amino Acid Antagonists; Frontal Lobe; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Haptens; Hippocampus; Hydroxyindoleacetic Acid; Immunoconjugates; Locomotion; Male; Memory; Mice; Mice, Inbred C57BL; Rabbits; Serotonin; Serum Albumin, Bovine	2019
Induction of Metabotropic Glutamate Receptor-Mediated Long-Term Depression in the Hippocampal Schaffer Collateral Pathway of Aging Rats. Methods in molecular biology (Clifton, N.J.), 2019, Volume: 1941 Topics: Aging; Animals; Electrophysiology; Glutamic Acid; Hippocampus; Long-Term Synaptic Depression; Rats; Receptors, Metabotropic Glutamate	2019
Combination of chick embryo and nutrient mixture prevent D-galactose-induced cognitive deficits, immune impairment and oxidative stress in aging rat model. Scientific reports, 2019, 03-11, Volume: 9, Issue:1 Topics: Aging; Animals; Antioxidants; B-Lymphocytes; Body Weight; Brain; Chick Embryo; Cognition Disorders; Disease Models, Animal; Galactose; Glutamic Acid; Intercellular Signaling Peptides and Proteins; Interleukin-2; Interleukin-4; Lipopolysaccharides; Liver; Male; Maze Learning; Memory; NF-kappa B; Nutrients; Ovum; Oxidative Stress; Rats, Sprague-Dawley; Spleen; Stem Cell Factor; Toll-Like Receptor 4	2019
Vesicular Glutamatergic Transmission in Noise-Induced Loss and Repair of Cochlear Ribbon Synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019, 06-05, Volume: 39, Issue:23 Topics: Aging; Amino Acid Transport Systems, Acidic; Animals; Auditory Threshold; Calcium; Evoked Potentials, Auditory; Exocytosis; Female; Gene Dosage; Genes, Reporter; Glutamic Acid; Hair Cells, Auditory, Inner; Hair Cells, Auditory, Outer; Hearing Loss, Noise-Induced; Ion Transport; Male; Mice; Mice, Knockout; Receptors, AMPA; Recovery of Function; Spiral Ganglion; Synapses	2019
GABA and glutamate moderate beta-amyloid related functional connectivity in cognitively unimpaired old-aged adults. NeuroImage. Clinical, 2019, Volume: 22 Topics: Aged; Aging; Amyloid beta-Peptides; Aniline Compounds; Cerebellum; Cerebral Cortex; Connectome; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gray Matter; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neuroimaging; Positron-Emission Tomography; Thiazoles	2019
Lamotrigine Therapy and Biomarkers of Cerebral Energy Metabolism in Older Age Bipolar Depression. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2019, Volume: 27, Issue:8 Topics: Aged; Aging; Antipsychotic Agents; Aspartic Acid; Biomarkers; Bipolar Disorder; Cerebral Cortex; Creatine; Depression; Energy Metabolism; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Humans; Lamotrigine; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Severity of Illness Index; Treatment Outcome	2019
Paraquat as an Environmental Risk Factor in Parkinson's Disease Accelerates Age-Related Degeneration Via Rapid Influx of Extracellular Zn Molecular neurobiology, 2019, Volume: 56, Issue:11 Topics: Aging; Animals; Dopaminergic Neurons; Exocytosis; Extracellular Space; Glutamic Acid; Male; Paraquat; Parkinson Disease; Presynaptic Terminals; Rats, Wistar; Reactive Oxygen Species; Receptors, AMPA; Risk Factors; Substantia Nigra; Zinc	2019
Longer Repetition Time Proton MR Spectroscopy Shows Increasing Hippocampal and Parahippocampal Metabolite Concentrations with Aging. Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2019, Volume: 29, Issue:5 Topics: Adolescent; Adult; Aging; Aspartic Acid; Choline; Creatine; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Inositol; Male; Middle Aged; Parahippocampal Gyrus; Proton Magnetic Resonance Spectroscopy; Protons; Young Adult	2019
Diabetes and the link between neuroplasticity and glutamate in the aging human motor cortex. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2019, Volume: 130, Issue:9 Topics: Aged; Aged, 80 and over; Aging; Aspartic Acid; Creatine; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Intolerance; Glutamic Acid; Glutamine; Glutathione; Glycerylphosphorylcholine; Humans; Inositol; Insulin Resistance; Magnetic Resonance Spectroscopy; Male; Middle Aged; Motor Cortex; Neuronal Plasticity; Phosphocreatine; Phosphorylcholine; Prediabetic State; Theta Rhythm; Transcranial Magnetic Stimulation	2019
Age-dependent effects of (+)-MK801 treatment on glutamate release and metabolism in the rat medial prefrontal cortex. Neurochemistry international, 2019, Volume: 129 Topics: Aging; Animals; Dizocilpine Maleate; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Gliosis; Glutamic Acid; Male; Oxidative Stress; Prefrontal Cortex; Random Allocation; Rats; Stereoisomerism	2019
Regional Metabolic Patterns of Abnormal Postoperative Behavioral Performance in Aged Mice Assessed by Neuroscience bulletin, 2020, Volume: 36, Issue:1 Topics: Aging; Anesthesia; Animals; Anxiety; Aspartic Acid; Brain; Cerebral Cortex; Cognitive Dysfunction; Female; Glutamic Acid; Hippocampus; Isoflurane; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Motor Activity; Proton Magnetic Resonance Spectroscopy	2020
Age- and gender-related metabonomic alterations in striatum and cerebellar cortex in rats. Brain research, 2013, Apr-24, Volume: 1507 Topics: Aging; Animals; Cerebellar Cortex; Corpus Striatum; Creatine; Female; Glutamic Acid; Inositol; Lactic Acid; Male; Metabolomics; Radionuclide Imaging; Rats; Rats, Sprague-Dawley; Sex Factors; Taurine	2013
Atrophy of pyramidal neurons and increased stress-induced glutamate levels in CA3 following chronic suppression of adult neurogenesis. Brain structure & function, 2014, Volume: 219, Issue:3 Topics: Aging; Animals; Animals, Newborn; Atrophy; Dentate Gyrus; Female; Glutamic Acid; Hippocampus; Male; Mice, Inbred C57BL; Neurogenesis; Neurons; Pyramidal Cells; Stress, Physiological	2014
Effects of age and sex on the concentrations of glutamate and glutamine in the human brain. Journal of magnetic resonance imaging : JMRI, 2013, Volume: 38, Issue:6 Topics: Adult; Aging; Aspartic Acid; Choline; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurotransmitter Agents; Reproducibility of Results; Sensitivity and Specificity; Sex Factors; Young Adult	2013
Maximising umami taste in meat using natural ingredients: effects on chemistry, sensory perception and hedonic liking in young and old consumers. Journal of the science of food and agriculture, 2013, Volume: 93, Issue:13 Topics: Adult; Aged; Aged, 80 and over; Aging; Animals; Consumer Behavior; Cooking; Drug Synergism; Female; Flavoring Agents; Food Preferences; Glutamic Acid; Humans; Male; Meat; Middle Aged; Perception; Ribonucleotides; Sensation; Taste	2013
Dynein mutations associated with hereditary motor neuropathies impair mitochondrial morphology and function with age. Neurobiology of disease, 2013, Volume: 58 Topics: Aging; Animals; Cells, Cultured; Cytoplasmic Dyneins; Embryo, Mammalian; Female; Glucagon; Glutamic Acid; Humans; Insulin; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Muscular Atrophy, Spinal; Mutation; Superoxide Dismutase; Superoxide Dismutase-1; Transfection	2013
Neurodegeneration after transient brain ischemia in aged mice: beneficial effects of bilobalide. Brain research, 2013, Sep-05, Volume: 1529 Topics: Adenosine Triphosphate; Aging; Animals; Brain Infarction; Cyclopentanes; Disease Models, Animal; Extracellular Fluid; Female; Furans; Ginkgolides; Glucose; Glutamic Acid; Infarction, Middle Cerebral Artery; Locomotion; Mice; Microdialysis; Mitochondria; Multienzyme Complexes; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Phosphorylation	2013
Motor system alterations in retired former athletes: the role of aging and concussion history. BMC neurology, 2013, Aug-26, Volume: 13 Topics: Age Factors; Aged; Aging; Analysis of Variance; Apolipoproteins E; Aspartic Acid; Brain; Brain Concussion; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Middle Aged; Motor Activity; Motor Cortex; Neuropsychological Tests; Photic Stimulation; Protons; Reaction Time; Regression Analysis; Surveys and Questionnaires	2013
Age-related changes in a patient with Pelizaeus-Merzbacher disease determined by repeated 1H-magnetic resonance spectroscopy. Journal of child neurology, 2014, Volume: 29, Issue:2 Topics: Aging; Aspartic Acid; Case-Control Studies; Child, Preschool; Creatine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Infant; Inositol; Magnetic Resonance Spectroscopy; Male; Parietal Lobe; Pelizaeus-Merzbacher Disease	2014
Cerebral level of vGlut1 is increased and level of glycine is decreased in TgSwDI mice. Journal of Alzheimer's disease : JAD, 2014, Volume: 39, Issue:1 Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Autoradiography; Cerebellum; Cerebral Cortex; Disease Models, Animal; Disease Progression; Glutamic Acid; Glycine; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Receptors, N-Methyl-D-Aspartate; Vesicular Glutamate Transport Protein 1	2014
1H NMR metabolomic signatures in five brain regions of the AβPPswe Tg2576 mouse model of Alzheimer's disease at four ages. Journal of Alzheimer's disease : JAD, 2014, Volume: 39, Issue:1 Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Biomarkers; Cerebellum; Cerebral Cortex; Disease Models, Animal; Genotype; Glutamic Acid; Hippocampus; Magnetic Resonance Spectroscopy; Male; Mesencephalon; Metabolome; Mice; Mice, Transgenic; Tissue Extracts	2014
Functional proteomics related to energy metabolism of synaptosomes from different neuronal systems of rat hippocampus during aging. Journal of proteome research, 2013, Dec-06, Volume: 12, Issue:12 Topics: Acetylcholine; Aging; Animals; CA1 Region, Hippocampal; Citric Acid Cycle; Dentate Gyrus; Glutamic Acid; Glycolysis; Humans; Kinetics; Male; Neurons; Proteomics; Pyramidal Cells; Rats; Rats, Wistar; Synaptosomes	2013
A novel approach to rapidly prevent age-related cognitive decline. Aging cell, 2014, Volume: 13, Issue:2 Topics: Aging; Animals; Behavior, Animal; Biomarkers; Cell Count; Clioquinol; Cognition Disorders; Dendritic Spines; Female; Glutamic Acid; Hippocampus; Maze Learning; Mice; Mice, Inbred C57BL; Neurogenesis; Neuronal Plasticity; Protein Phosphatase 2; Receptors, Glutamate; Synapses; Vesicular Glutamate Transport Protein 1; Zinc	2014
Dopamine and glutamate receptor genes interactively influence episodic memory in old age. Neurobiology of aging, 2014, Volume: 35, Issue:5 Topics: Adult; Aged; Aging; Dopamine; Epistasis, Genetic; Female; Genetic Variation; Genotype; Glutamic Acid; Humans; Male; Memory, Episodic; Middle Aged; Neurotransmitter Agents; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Young Adult	2014
Metabolism changes during aging in the hippocampus and striatum of glud1 (glutamate dehydrogenase 1) transgenic mice. Neurochemical research, 2014, Volume: 39, Issue:3 Topics: Aging; Animals; Aspartic Acid; Corpus Striatum; Glutamate Dehydrogenase; Glutamic Acid; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Receptors, Glutamate; Synapses	2014
High-field proton magnetic resonance spectroscopy reveals metabolic effects of normal brain aging. Neurobiology of aging, 2014, Volume: 35, Issue:7 Topics: Aging; Animals; Aspartic Acid; Brain; Choline; Functional Neuroimaging; Glucose; Glutamic Acid; Magnetic Resonance Spectroscopy; Male; Neurochemistry; Protons; Rats; Rats, Inbred F344	2014
Longitudinal neurochemical modifications in the aging mouse brain measured in vivo by 1H magnetic resonance spectroscopy. Neurobiology of aging, 2014, Volume: 35, Issue:7 Topics: Aging; Alanine; Animals; Cerebral Cortex; Cognition; Corpus Striatum; Energy Metabolism; Ethanolamines; Female; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Hippocampus; Hydrogen; Lactates; Magnetic Resonance Spectroscopy; Male; Membrane Lipids; Mice; Mice, Inbred C57BL; Receptors, Estrogen; Sex Characteristics; Synaptic Transmission	2014
Gene expression patterns in the hippocampus during the development and aging of Glud1 (Glutamate Dehydrogenase 1) transgenic and wild type mice. BMC neuroscience, 2014, Mar-04, Volume: 15 Topics: Aging; Animals; Gene Expression Regulation, Developmental; Glutamate Dehydrogenase; Glutamic Acid; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Proteome; Tissue Distribution; Transcriptome; Up-Regulation	2014
Caffeine and diphenyl diselenide improve long-term memory impaired in middle-aged rats. Experimental gerontology, 2014, Volume: 53 Topics: Aging; Animals; Benzene Derivatives; Caffeine; CREB-Binding Protein; Dietary Supplements; Drug Evaluation, Preclinical; Glutamic Acid; Hippocampus; Male; Memory Disorders; Memory, Long-Term; Memory, Short-Term; Organoselenium Compounds; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Recognition, Psychology; Tissue Culture Techniques	2014
Altered glutamate/GABA equilibrium in aged mice cortex influences cortical plasticity. Brain structure & function, 2015, Volume: 220, Issue:3 Topics: Aging; Animals; Conditioning, Classical; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Presynaptic Terminals; Somatosensory Cortex; Vesicular Glutamate Transport Protein 2	2015
Caloric restriction impedes age-related decline of mitochondrial function and neuronal activity. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:9 Topics: Aging; Animals; Caloric Restriction; Glutamic Acid; Glutamine; Male; Mitochondria; Rats; Rats, Inbred F344; Synaptic Transmission	2014
The impact of ageing on adipose structure, function and vasculature in the B6D2F1 mouse: evidence of significant multisystem dysfunction. The Journal of physiology, 2014, Sep-15, Volume: 592, Issue:18 Topics: Adipose Tissue; Aging; Animals; Arteries; Body Weight; Carnitine; Glutamic Acid; Malates; Male; Mice; Mitochondria; Neovascularization, Physiologic; Oxidative Stress; Oxygen Consumption; Succinic Acid; Triglycerides; Tyrosine; Vasodilation	2014
Inhibition of cytoplasmic p53 differentially modulates Ca(2+) signaling and cellular viability in young and aged striata. Experimental gerontology, 2014, Volume: 58 Topics: Age Factors; Aging; Animals; Basal Ganglia; bcl-2-Associated X Protein; Calcium Signaling; Cell Survival; Cytoplasm; Glutamic Acid; Glutathione; Homeostasis; In Vitro Techniques; Membrane Potential, Mitochondrial; Mitochondria; Oxidative Stress; Phosphorylation; Rats, Wistar; Reactive Oxygen Species; Sulfonamides; Tumor Suppressor Protein p53; Ultraviolet Rays	2014
Exocytosis of gliotransmitters from cortical astrocytes: implications for synaptic plasticity and aging. Biochemical Society transactions, 2014, Volume: 42, Issue:5 Topics: Adenosine Triphosphate; Aging; Animals; Astrocytes; Calcium Signaling; Cell Communication; Exocytosis; Glutamic Acid; Humans; Neocortex; Nerve Tissue Proteins; Neuronal Plasticity; SNARE Proteins; Synaptic Transmission	2014
Caffeine suppresses exercise-enhanced long-term and location memory in middle-aged rats: Involvement of hippocampal Akt and CREB signaling. Chemico-biological interactions, 2014, Nov-05, Volume: 223 Topics: Aging; Animals; Caffeine; Cyclic AMP Response Element-Binding Protein; Glutamic Acid; Hippocampus; Male; Memory Disorders; Memory, Long-Term; Physical Exertion; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; Spatial Memory; Swimming	2014
Tonic glutamate in CA1 of aging rats correlates with phasic glutamate dysregulation during seizure. Epilepsia, 2014, Volume: 55, Issue:11 Topics: 4-Aminopyridine; Aging; Animals; Behavior, Animal; CA1 Region, Hippocampal; Glutamic Acid; Hippocampus; Male; Rats, Inbred F344; Seizures; Synaptic Transmission	2014
Age related changes in metabolite concentrations in the normal spinal cord. PloS one, 2014, Volume: 9, Issue:10 Topics: Adult; Age Factors; Aged; Aging; Aspartic Acid; Choline; Creatine; Female; Glutamic Acid; Glutamine; Healthy Volunteers; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Reference Values; Spinal Cord; Young Adult	2014
Glutamatergic regulation prevents hippocampal-dependent age-related cognitive decline through dendritic spine clustering. Proceedings of the National Academy of Sciences of the United States of America, 2014, Dec-30, Volume: 111, Issue:52 Topics: Aging; Animals; CA1 Region, Hippocampal; Cognition; Dendrites; Glutamic Acid; Male; Memory; Neuroprotective Agents; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Riluzole; Synapses; Synaptic Transmission	2014
Effects of aging on glutamate neurotransmission in the substantia nigra of Gdnf heterozygous mice. Neurobiology of aging, 2015, Volume: 36, Issue:3 Topics: Aging; Animals; Dopaminergic Neurons; Excitatory Amino Acid Transporter 2; Female; Glial Cell Line-Derived Neurotrophic Factor; Glutamic Acid; Heterozygote; Male; Mice, Inbred C57BL; Nerve Degeneration; Substantia Nigra; Subthalamic Nucleus; Synaptic Transmission	2015
Role of CtBP2 in the Apoptosis of Retinal Ganglion Cells. Cellular and molecular neurobiology, 2015, Volume: 35, Issue:5 Topics: Aging; Alcohol Oxidoreductases; Animals; Apoptosis; Blotting, Western; Cell Survival; Cells, Cultured; Co-Repressor Proteins; DNA-Binding Proteins; Glutamic Acid; Immunohistochemistry; Intraocular Pressure; Male; Mice, Inbred C57BL; Mice, Inbred DBA; Phosphoproteins; Retinal Ganglion Cells	2015
Different pools of glutamate receptors mediate sensitivity to ambient glutamate in the cochlear nucleus. Journal of neurophysiology, 2015, Jun-01, Volume: 113, Issue:10 Topics: Action Potentials; Aging; Animals; Animals, Newborn; Cochlear Nucleus; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agents; Glutamic Acid; In Vitro Techniques; Mice; Mice, Inbred CBA; Receptors, Glutamate; Sodium Channel Blockers; Tetrodotoxin	2015
Impact of family history of alcoholism on glutamine/glutamate ratio in anterior cingulate cortex in substance-naïve adolescents. Developmental cognitive neuroscience, 2015, Volume: 16 Topics: Adolescent; Aging; Alcoholism; Brain Chemistry; Child; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Impulsive Behavior; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Young Adult	2015
Taste-active compound levels in Korean native chicken meat: The effects of bird age and the cooking process. Poultry science, 2015, Volume: 94, Issue:8 Topics: Aging; Animals; Carbohydrates; Chickens; Cooking; Cysteine; Fatty Acids; Glutamic Acid; Inosine Monophosphate; Meat; Republic of Korea; Taste	2015
A quantitative analysis of (1)H-MR spectroscopy at 3.0 T of three brain regions from childhood to middle age. The British journal of radiology, 2015, Volume: 88, Issue:1052 Topics: Adolescent; Adult; Aging; Analysis of Variance; Aspartic Acid; Brain; Child; Creatinine; Female; Glutamic Acid; Glutamine; Healthy Volunteers; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Matrix Metalloproteinase 9; Middle Aged; Young Adult	2015
Interactions between glutamate, dopamine, and the neuronal signature of response inhibition in the human striatum. Human brain mapping, 2015, Volume: 36, Issue:10 Topics: Adult; Aging; Brain Mapping; Caudate Nucleus; Corpus Striatum; Dopamine; Dopaminergic Neurons; Female; Glutamic Acid; Humans; Inhibition, Psychological; Magnetic Resonance Imaging; Male; Neurons; Positron-Emission Tomography; Psychomotor Performance; Reaction Time	2015
Enhancing glutamatergic transmission during adolescence reverses early-life stress-induced deficits in the rewarding effects of cocaine in rats. Neuropharmacology, 2015, Volume: 99 Topics: Administration, Intravenous; Aging; Amino Acid Transport System X-AG; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Maternal Deprivation; Memantine; Rats; Receptors, N-Methyl-D-Aspartate; Reward; Riluzole; Self Administration; Stress, Psychological	2015
Astrocytes from adult Wistar rats aged in vitro show changes in glial functions. Neurochemistry international, 2015, Volume: 90 Topics: Aging; Animals; Antioxidants; Astrocytes; Brain; Cells, Cultured; Glial Fibrillary Acidic Protein; Glutamic Acid; Male; Nerve Growth Factors; Neuroglia; Rats, Wistar	2015
Protective effects of NMDA receptor antagonist, memantine, against senescence of PC12 cells: A possible role of nNOS and combined effects with donepezil. Experimental gerontology, 2015, Volume: 72 Topics: Aging; Alzheimer Disease; Animals; beta-Galactosidase; Cholinesterase Inhibitors; Cognition; Disease Models, Animal; Donepezil; Glutamic Acid; Hippocampus; Indans; Male; Maze Learning; Memantine; Memory; Mice; Neuronal Plasticity; Nitric Oxide Synthase Type I; PC12 Cells; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate	2015
Region-specific changes in presynaptic agmatine and glutamate levels in the aged rat brain. Neuroscience, 2016, Jan-15, Volume: 312 Topics: Aging; Agmatine; Animals; Glutamic Acid; Immunohistochemistry; Male; Prefrontal Cortex; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Temporal Lobe	2016
Exercise-Mediated Increase in Nigral Tyrosine Hydroxylase Is Accompanied by Increased Nigral GFR-α1 and EAAC1 Expression in Aging Rats. ACS chemical neuroscience, 2016, Feb-17, Volume: 7, Issue:2 Topics: Aging; Animals; Body Weight; Dopamine; Excitatory Amino Acid Transporter 3; Exercise Test; Gene Expression Regulation; Glial Cell Line-Derived Neurotrophic Factor; Glial Cell Line-Derived Neurotrophic Factor Receptors; Glutamic Acid; Locomotion; Male; Physical Conditioning, Animal; Rats; Rats, Inbred F344; Substantia Nigra; Synaptosomes; Time Factors; Tritium; Tyrosine 3-Monooxygenase	2016
The ratio of N-acetyl aspartate to glutamate correlates with disease duration of amyotrophic lateral sclerosis. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2016, Volume: 27 Topics: Aged; Aging; Amyotrophic Lateral Sclerosis; Aspartic Acid; Biomarkers; Cell Death; Cross-Sectional Studies; Female; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Motor Cortex; Neurons	2016
Shifts in excitatory/inhibitory balance by juvenile stress: A role for neuron-astrocyte interaction in the dentate gyrus. Glia, 2016, Volume: 64, Issue:6 Topics: Aging; Animals; Astrocytes; Cell Communication; Dentate Gyrus; Electric Stimulation; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neurons; Rats, Wistar; Real-Time Polymerase Chain Reaction; Synaptic Transmission	2016
Age-related changes in anterior cingulate cortex glutamate in schizophrenia: A (1)H MRS Study at 7 Tesla. Schizophrenia research, 2016, Volume: 172, Issue:1-3 Topics: Adult; Aging; Antipsychotic Agents; Aspartic Acid; Choline; Creatine; Dipeptides; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glutathione; Gyrus Cinguli; Humans; Inositol; Male; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia	2016
Abnormality in glutamine-glutamate cycle in the cerebrospinal fluid of cognitively intact elderly individuals with major depressive disorder: a 3-year follow-up study. Translational psychiatry, 2016, Mar-01, Volume: 6 Topics: Aged; Aging; Chromatography, High Pressure Liquid; Cognition; Depressive Disorder, Major; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Humans; Male; Psychiatric Status Rating Scales; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission	2016
Age and Alzheimer's disease gene expression profiles reversed by the glutamate modulator riluzole. Molecular psychiatry, 2017, Volume: 22, Issue:2 Topics: Age Factors; Aging; Alzheimer Disease; Animals; Cognition; Cognitive Aging; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Male; Memory; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Riluzole; Synaptic Transmission; Transcriptome	2017
Enhanced Cognition and Hypoglutamatergic Signaling in a Growth Hormone Receptor Knockout Mouse Model of Successful Aging. The journals of gerontology. Series A, Biological sciences and medical sciences, 2017, 03-01, Volume: 72, Issue:3 Topics: Aging; Animals; Cognition; Female; Glutamic Acid; Memory; Mice; Mice, Knockout; Models, Animal; Receptors, Somatotropin; Signal Transduction; Spatial Learning	2017
Glutamate Increases In Vitro Survival and Proliferation and Attenuates Oxidative Stress-Induced Cell Death in Adult Spinal Cord-Derived Neural Stem/Progenitor Cells via Non-NMDA Ionotropic Glutamate Receptors. Stem cells and development, 2016, 08-15, Volume: 25, Issue:16 Topics: Adult Stem Cells; Aging; Animals; Brain; Cell Death; Cell Proliferation; Cell Survival; Female; Glutamic Acid; Neural Stem Cells; Oxidative Stress; Phenotype; Rats, Transgenic; Rats, Wistar; Receptors, AMPA; Receptors, Ionotropic Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord	2016
Glutamate release and uptake processes are altered in a new mouse model of amyotrophic lateral sclerosis. Doklady. Biochemistry and biophysics, 2016, Volume: 468, Issue:1 Topics: Aging; Amyotrophic Lateral Sclerosis; Animals; Cations, Monovalent; Central Nervous System Agents; Cerebral Cortex; Disease Models, Animal; Glutamic Acid; Mice, Transgenic; Potassium; Potassium Chloride; RNA-Binding Protein FUS; Sodium; Synaptosomes; Tritium	2016
Long-term hippocampal glutamate synapse and astrocyte dysfunctions underlying the altered phenotype induced by adolescent THC treatment in male rats. Pharmacological research, 2016, Volume: 111 Topics: Aging; Animals; Astrocytes; Behavior, Animal; Dronabinol; Glutamic Acid; Hippocampus; Interpersonal Relations; Male; Memory; Phenotype; Prefrontal Cortex; Rats, Sprague-Dawley; Receptors, Ionotropic Glutamate; Swimming; Synapses	2016
Age-dependent changes in the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic model of Alzheimer's disease: implications for neurometabolic regulation. Neurobiology of aging, 2016, Volume: 46 Topics: Aging; Alzheimer Disease; Animals; Disease Models, Animal; Energy Metabolism; Glutamic Acid; Hippocampus; Mice, Transgenic; Microelectrodes; Mitochondria; Neurotransmitter Agents; Nitric Oxide; Oxidative Phosphorylation; Oxygen Consumption; Peroxynitrous Acid; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tyrosine	2016
Altered Glutamate and Regional Cerebral Blood Flow Levels in Schizophrenia: A Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017, Volume: 42, Issue:2 Topics: Adolescent; Adult; Aging; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Schizophrenic Psychology; White Matter; Young Adult	2017
Anti-aging effects of guanosine in glial cells. Purinergic signalling, 2016, Volume: 12, Issue:4 Topics: Aging; Animals; Astrocytes; Cells, Cultured; Cerebral Cortex; Cytokines; Glutamate-Ammonia Ligase; Glutamic Acid; Glutathione; Guanosine; Heme Oxygenase-1; Male; Rats; Rats, Wistar	2016
Developmental delay in motor skill acquisition in Niemann-Pick C1 mice reveals abnormal cerebellar morphogenesis. Acta neuropathologica communications, 2016, 09-01, Volume: 4, Issue:1 Topics: Aging; Animals; Animals, Newborn; Cerebellum; Cohort Studies; Developmental Disabilities; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamic Acid; Intracellular Signaling Peptides and Proteins; Male; Mice, Inbred BALB C; Mice, Transgenic; Motor Skills; Myelin Sheath; Neuroglia; Niemann-Pick C1 Protein; Niemann-Pick Disease, Type C; Postural Balance; Proteins; Severity of Illness Index; Synapses	2016
Microglia derived from the axotomized adult rat facial nucleus uptake glutamate and metabolize it to glutamine in vitro. Neurochemistry international, 2017, Volume: 102 Topics: Aging; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Biological Transport; Cells, Cultured; Facial Nucleus; Glutamic Acid; Glutamine; Male; Microglia; Neurons; Rats, Wistar	2017
Cyclophilin D Promotes Brain Mitochondrial F1FO ATP Synthase Dysfunction in Aging Mice. Journal of Alzheimer's disease : JAD, 2017, Volume: 55, Issue:4 Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Aging; Animals; Brain; Carrier Proteins; Cyclophilins; Gene Expression Regulation; Glutamic Acid; Immunoprecipitation; Membrane Proteins; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Proton-Translocating ATPases; Oxygen Consumption; Peptidyl-Prolyl Isomerase F	2017
Age-dependent regulation of GABA transmission by kappa opioid receptors in the basolateral amygdala of Sprague-Dawley rats. Neuropharmacology, 2017, 05-01, Volume: 117 Topics: Aging; Animals; Basolateral Nuclear Complex; Benzeneacetamides; gamma-Aminobutyric Acid; Glutamic Acid; Inhibitory Postsynaptic Potentials; Male; Naltrexone; Pyrrolidines; Rats; Receptors, Opioid, kappa; Synaptic Transmission	2017
Hypothalamic damage in multiple sclerosis correlates with disease activity, disability, depression, and fatigue. Neurological research, 2017, Volume: 39, Issue:4 Topics: Adult; Aging; Aspartic Acid; Case-Control Studies; Choline; Creatine; Cross-Sectional Studies; Depression; Disability Evaluation; Fatigue; Female; Glutamic Acid; Humans; Hypothalamus; Inositol; Male; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Proton Magnetic Resonance Spectroscopy; Psychiatric Status Rating Scales; Severity of Illness Index	2017
Characterization of the influence of age on GABA Aging, 2017, 02-16, Volume: 9, Issue:2 Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Electroencephalography; Electromyography; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Middle Aged; Prefrontal Cortex; Receptors, GABA-A; Receptors, Glutamate; Transcranial Magnetic Stimulation; Young Adult	2017
Further studies of the effects of aging on arginine metabolites in the rat vestibular nucleus and cerebellum. Neuroscience, 2017, 04-21, Volume: 348 Topics: Aging; Animals; Arginine; Cerebellum; Citrulline; Glutamic Acid; Male; Nitric Oxide Synthase; Ornithine; Rats; Rats, Sprague-Dawley; Vestibular Nuclei	2017
Antibodies to Glutamate Reversed the Amnesic Effects of Proinflammatory S100A9 Protein Fibrils in Aged C57Bl/6 Mice. Bulletin of experimental biology and medicine, 2017, Volume: 162, Issue:4 Topics: Aging; Amnesia; Amyloidogenic Proteins; Animals; Antibodies; Avoidance Learning; Calgranulin B; Excitatory Amino Acid Antagonists; Glutamic Acid; Inflammation; Male; Maze Learning; Mice; Mice, Inbred C57BL; Motor Activity; Rabbits; Spatial Memory	2017
Activation of group I metabotropic glutamate receptors induces long-term depression in the hippocampal CA1 region of adult rats in vitro. Neuroscience research, 2008, Volume: 62, Issue:1 Topics: Age Factors; Aging; Animals; Axons; Benzoates; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Long-Term Synaptic Depression; Neural Inhibition; Neural Pathways; Neurons; Organ Culture Techniques; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Synaptic Membranes; Synaptic Transmission	2008
Synapsin-dependent development of glutamatergic synaptic vesicles and presynaptic plasticity in postnatal mouse brain. Neuroscience, 2009, Jan-12, Volume: 158, Issue:1 Topics: Aging; Animals; Animals, Newborn; Gene Expression Regulation, Developmental; Glutamic Acid; Hippocampus; Mice; Mice, Knockout; Neurogenesis; Neuronal Plasticity; Organ Culture Techniques; Presynaptic Terminals; Synapsins; Synaptic Vesicles; Vesicular Glutamate Transport Protein 1	2009
Restoration of the luteinizing hormone surge in middle-aged female rats by altering the balance of GABA and glutamate transmission in the medial preoptic area. Biology of reproduction, 2008, Volume: 79, Issue:5 Topics: Age Factors; Aging; Animals; Estradiol; Estrous Cycle; Female; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Luteinizing Hormone; Preoptic Area; Progesterone; Rats; Rats, Sprague-Dawley; Vesicular Glutamate Transport Protein 2; Vesicular Inhibitory Amino Acid Transport Proteins	2008
Expression and activation of N-methyl-D-aspartate receptor subunit-1 receptor subunits in gonadotrophin-releasing hormone neurones of young and middle-aged mice during the luteinising hormone surge. Journal of neuroendocrinology, 2008, Volume: 20, Issue:10 Topics: Aging; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Calmodulin; CREB-Binding Protein; Cyclic AMP Response Element-Binding Protein; Estrous Cycle; Female; Glutamic Acid; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Mice; Mice, Inbred C57BL; Neurons; Ovariectomy; Protein Subunits; Receptors, N-Methyl-D-Aspartate	2008
Effect of bacterial lipopolysaccharide on the reproductive axis of prepubertal and peripubertal female rats. Ontogenic changes in the immune-neuroendocrine interactions. Neuroimmunomodulation, 2008, Volume: 15, Issue:2 Topics: Adipose Tissue; Aging; Animals; Bacterial Infections; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; Hypothalamus; Inflammation Mediators; Leptin; Lipopolysaccharides; Luteinizing Hormone; Neuroimmunomodulation; Neurosecretory Systems; Nitric Oxide Synthase; Rats; Rats, Wistar; Reproduction; Sexual Maturation; Stress, Physiological; Up-Regulation	2008
Changes in glutamate decarboxylase enzyme activity and tau-protein phosphorylation in the hippocampus of old rats exposed to chronic mild stress: reversal with the neuronal nitric oxide synthase inhibitor 7-nitroindazole. Pharmacology, biochemistry, and behavior, 2009, Volume: 91, Issue:3 Topics: Aging; Animals; Blotting, Western; Chromatography, High Pressure Liquid; Chronic Disease; Enzyme Inhibitors; Feeding Behavior; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Hippocampus; Indazoles; Male; Neuroprotective Agents; Nitric Oxide Synthase Type I; Phosphorylation; Rats; Rats, Wistar; Stress, Psychological; tau Proteins	2009
Neurotransmitter release during delay eyeblink classical conditioning: role of norepinephrine in consolidation and effect of age. Neurobiology of learning and memory, 2009, Volume: 92, Issue:3 Topics: Adrenergic beta-Antagonists; Aging; Animals; Association Learning; Cerebellum; Conditioning, Eyelid; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Male; Memory; Neurotransmitter Agents; Norepinephrine; Propranolol; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta; Time Factors	2009
17beta-estradiol affects GABAergic transmission in developing hippocampus. Brain research, 2008, Nov-19, Volume: 1241 Topics: Age Factors; Aging; Animals; Drug Administration Schedule; Estradiol; Excitatory Amino Acid Antagonists; Female; Flurazepam; GABA Modulators; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Inhibitory Postsynaptic Potentials; Male; Neural Inhibition; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Wistar; Synapses; Up-Regulation	2008
Critical age-related loss of cofactors of neuron cytochrome C oxidase reversed by estrogen. Experimental neurology, 2009, Volume: 215, Issue:2 Topics: Age Factors; Aging; Animals; Brain; Bromodeoxyuridine; Cardiolipins; Cell Respiration; Cells, Cultured; Electron Transport Complex IV; Embryo, Mammalian; Enzyme Inhibitors; Estradiol; Estrogens; Glutamic Acid; Male; Mitochondria; Neurons; Oxygen Consumption; Potassium Cyanide; Rats; Rats, Inbred F344	2009
Effect of amino acids on cell proliferation and protein p53 expression in organotypic culture of lymphoid tissue from neonatal rats. Cell biology international, 2008, Volume: 32, Issue:12 Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Asparagine; Cell Differentiation; Cell Proliferation; Down-Regulation; Glutamic Acid; Lymphocyte Activation; Lymphoid Tissue; Lysine; Organ Culture Techniques; Rats; Rats, Wistar; Spleen; T-Lymphocytes; Tumor Suppressor Protein p53; Up-Regulation	2008
Developmental sensitivity of hippocampal interneurons to ethanol: involvement of the hyperpolarization-activated current, Ih. Journal of neurophysiology, 2009, Volume: 101, Issue:1 Topics: Action Potentials; Aging; Animals; Central Nervous System Depressants; Cesium; Chlorides; Cyclic Nucleotide-Gated Cation Channels; Data Interpretation, Statistical; Electrophysiology; Ethanol; GABA Antagonists; Glutamic Acid; Hippocampus; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Interneurons; Male; Patch-Clamp Techniques; Potassium Channels; Pyramidal Cells; Pyrimidines; Rats; Rats, Sprague-Dawley	2009
Growth arrest and DNA damage protein 45b (Gadd45b) protects retinal ganglion cells from injuries. Neurobiology of disease, 2009, Volume: 33, Issue:1 Topics: Aging; Animals; Antigens, Differentiation; Cell Death; Cells, Cultured; Glutamic Acid; Intraocular Pressure; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Paraquat; Rats; Rats, Wistar; Retina; Retinal Ganglion Cells; RNA, Small Interfering; Tumor Necrosis Factor-alpha	2009
Glutamatergic transmission is sustained at a later period of development of medial nucleus of the trapezoid body-lateral superior olive synapses in circling mice. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Nov-26, Volume: 28, Issue:48 Topics: Aging; Animals; Auditory Pathways; Auditory Perception; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Immunohistochemistry; Male; Mice; Mice, Mutant Strains; Mice, Transgenic; Neurogenesis; Olivary Nucleus; Patch-Clamp Techniques; Pons; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Potentials; Synaptic Transmission	2008
Ammonium-evoked alterations in intracellular sodium and pH reduce glial glutamate transport activity. Glia, 2009, Volume: 57, Issue:9 Topics: Aging; Animals; Aspartic Acid; Astrocytes; Biological Transport; Bumetanide; Cells, Cultured; Central Nervous System Agents; D-Aspartic Acid; Glutamic Acid; Hippocampus; Hydrogen-Ion Concentration; Immunohistochemistry; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Sodium; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2	2009
Impaired calcium homeostasis in aged hippocampal neurons. Neuroscience letters, 2009, Feb-20, Volume: 451, Issue:2 Topics: Aging; Animals; Calcium; Calcium Signaling; Calpain; Cells, Cultured; Cellular Senescence; Glutamic Acid; Hippocampus; Hydrogen Peroxide; Nerve Degeneration; Neurons; Neurotoxins; Organic Chemicals; Oxidants; Oxidative Stress; Rats; Rats, Sprague-Dawley	2009
Repeated alcohol administration during adolescence causes changes in the mesolimbic dopaminergic and glutamatergic systems and promotes alcohol intake in the adult rat. Journal of neurochemistry, 2009, Volume: 108, Issue:4 Topics: Aging; Alcohol-Induced Disorders, Nervous System; Alcoholism; Animals; Animals, Newborn; Central Nervous System Depressants; Disease Models, Animal; Dopamine; Drug Administration Schedule; Ethanol; Glutamic Acid; Limbic System; Male; Neural Pathways; Neuronal Plasticity; Nucleus Accumbens; Rats; Rats, Wistar; Reward; Synaptic Transmission; Ventral Tegmental Area	2009
Age-dependent enhancement of inhibitory synaptic transmission in CA1 pyramidal neurons via GluR5 kainate receptors. Hippocampus, 2009, Volume: 19, Issue:8 Topics: Aging; Animals; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Patch-Clamp Techniques; Presynaptic Terminals; Pyramidal Cells; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Synaptic Transmission; Time Factors; Vesicular Glutamate Transport Proteins	2009
Glutamate toxicity in the striatum of the R6/2 Huntington's disease transgenic mice is age-dependent and correlates with decreased levels of glutamate transporters. Neurobiology of disease, 2009, Volume: 34, Issue:1 Topics: Aging; Analysis of Variance; Animals; Blotting, Western; Corpus Striatum; Electroencephalography; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Female; Glutamic Acid; Huntington Disease; Mice; Mice, Transgenic	2009
Brain metabolism in Rett syndrome: age, clinical, and genotype correlations. Annals of neurology, 2009, Volume: 65, Issue:1 Topics: Adolescent; Aging; Analysis of Variance; Aspartic Acid; Case-Control Studies; Child; Child, Preschool; Creatine; Female; Frontal Lobe; Genotype; Glutamic Acid; Glutamine; Humans; Infant; Inositol; Magnetic Resonance Spectroscopy; Methyl-CpG-Binding Protein 2; Mutation; Protons; Rett Syndrome; Severity of Illness Index	2009
Developmental increase of asynchronic glutamate release from hippocampal synapses in mutant taiep rat. Synapse (New York, N.Y.), 2009, Volume: 63, Issue:6 Topics: Aging; Animals; Animals, Newborn; Brain Chemistry; Electric Stimulation; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Mutation; Presynaptic Terminals; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Synaptic Transmission; Up-Regulation	2009
Restricted cortical and amygdaloid removal of vesicular glutamate transporter 2 in preadolescent mice impacts dopaminergic activity and neuronal circuitry of higher brain function. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Feb-18, Volume: 29, Issue:7 Topics: Aging; Amygdala; Animals; Antipsychotic Agents; Behavior, Animal; Cell Differentiation; Cerebral Cortex; Corpus Striatum; Dopamine; Glutamic Acid; Hippocampus; Male; Mice; Mice, Knockout; Neural Pathways; Neuronal Plasticity; Nucleus Accumbens; Schizophrenia; Sensory Gating; Synaptic Transmission; Vesicular Glutamate Transport Protein 2	2009
Cell type-specific development of NMDA receptors in the interneurons of rat prefrontal cortex. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:8 Topics: Action Potentials; Aging; Animals; Animals, Newborn; Cell Differentiation; Cell Shape; Dendrites; Epigenesis, Genetic; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; Interneurons; Lysine; Organ Culture Techniques; Patch-Clamp Techniques; Prefrontal Cortex; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Staining and Labeling; Synaptic Transmission	2009
Release of endogenous amino acids from the hippocampus and brain stem from developing and adult mice in ischemia. Neurochemical research, 2009, Volume: 34, Issue:9 Topics: Aging; Alanine; Animals; Aspartic Acid; Brain Ischemia; Brain Stem; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Male; Mice; Potassium; Serine; Taurine; Threonine	2009
Newborn- and adult-derived brain microvascular endothelial cells show age-related differences in phenotype and glutamate-evoked protease release. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2009, Volume: 29, Issue:6 Topics: Aging; Animals; Animals, Newborn; Biomarkers; Brain; Cell Shape; Cells, Cultured; Endothelial Cells; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glutamic Acid; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Microvessels; Monocarboxylic Acid Transporters; Phenotype; Protein Subunits; Receptors, N-Methyl-D-Aspartate; Symporters; Tissue Culture Techniques	2009
Not glutamate but endocannabinoids mediate retrograde suppression of cerebellar parallel fiber to Purkinje cell synaptic transmission in young adult rodents. Neuropharmacology, 2009, Volume: 57, Issue:2 Topics: Aging; Animals; Calcium; Cannabinoid Receptor Antagonists; Cannabinoid Receptor Modulators; Cerebellum; Endocannabinoids; Enzyme Inhibitors; Glutamic Acid; Humans; In Vitro Techniques; Lactones; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Inhibition; Orlistat; Piperidines; Purkinje Cells; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Cannabinoid; Synaptic Transmission	2009
Effect of ageing and ischemia on enzymatic activities linked to Krebs' cycle, electron transfer chain, glutamate and aminoacids metabolism of free and intrasynaptic mitochondria of cerebral cortex. Neurochemical research, 2009, Volume: 34, Issue:12 Topics: Aging; Animals; Aspartate Aminotransferase, Mitochondrial; Brain Ischemia; Cerebral Cortex; Citric Acid Cycle; Electron Transport; Electron Transport Complex IV; Energy Metabolism; Glutamate Dehydrogenase; Glutamic Acid; Malate Dehydrogenase; Male; Mitochondria; Rats; Rats, Wistar; Succinate Dehydrogenase; Synapses	2009
Decline of long-term potentiation (LTP) in the rat auditory cortex in vivo during postnatal life: involvement of NR2B subunits. Brain research, 2009, Aug-04, Volume: 1283 Topics: Aging; Animals; Auditory Cortex; Auditory Pathways; Electric Stimulation; Excitatory Amino Acid Antagonists; Geniculate Bodies; Glutamic Acid; Long-Term Potentiation; Male; Neuronal Plasticity; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Synaptic Potentials; Synaptic Transmission; Theta Rhythm	2009
Age-related changes in glutamate release in the CA3 and dentate gyrus of the rat hippocampus. Neurobiology of aging, 2011, Volume: 32, Issue:5 Topics: Aging; Animals; CA3 Region, Hippocampal; Dentate Gyrus; Glutamic Acid; Male; Memory; Perforant Pathway; Potassium Chloride; Rats; Rats, Inbred F344	2011
Neonatal exposure to MK801 promotes prepulse-induced delay in startle response time in adult rats. Experimental brain research, 2009, Volume: 197, Issue:3 Topics: Aging; Animals; Animals, Newborn; Apoptosis; Auditory Pathways; Biomarkers; Caspase 3; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Inferior Colliculi; Male; Nerve Degeneration; Nerve Net; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sensory Gating; Time	2009
Glutamate responsiveness of medial vestibular nucleus neurons in aged rats. Brain research bulletin, 2010, Jan-15, Volume: 81, Issue:1 Topics: Action Potentials; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glutamic Acid; In Vitro Techniques; Male; Microelectrodes; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Vestibular Nuclei	2010
Early development of the thalamic inhibitory feedback loop in the primary somatosensory system of the newborn mice. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Aug-05, Volume: 29, Issue:31 Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Mice; Neural Pathways; Patch-Clamp Techniques; Receptor, Serotonin, 5-HT1B; Receptors, AMPA; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin 5-HT1 Receptor Agonists; Somatosensory Cortex; Thalamic Nuclei; Thalamus; Time Factors	2009
Synchronization of GABAergic inputs to CA3 pyramidal cells precedes seizure-like event onset in juvenile rat hippocampal slices. Journal of neurophysiology, 2009, Volume: 102, Issue:4 Topics: Aging; Animals; CA3 Region, Hippocampal; Chlorides; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Intracellular Space; Magnesium Deficiency; Male; Periodicity; Picrotoxin; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-A; Seizures; Synapses; Synaptic Transmission; Time Factors	2009
Age-related changes in arginine and its metabolites in memory-associated brain structures. Neuroscience, 2009, Dec-01, Volume: 164, Issue:2 Topics: Aging; Analysis of Variance; Animals; Arginase; Arginine; Brain; Citrulline; gamma-Aminobutyric Acid; Glutamic Acid; Male; Memory; Nitric Oxide Synthase; Ornithine; Rats; Rats, Sprague-Dawley	2009
Alterations in calcium signaling and a decrease in Bcl-2 expression: possible correlation with apoptosis in aged striatum. Journal of neuroscience research, 2010, Feb-01, Volume: 88, Issue:2 Topics: Aging; Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Calcium; Corpus Striatum; Fluorescent Antibody Technique; Glutamic Acid; In Situ Nick-End Labeling; In Vitro Techniques; Mitochondria; N-Methylaspartate; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Time Factors	2010
Altered brain mitochondrial metabolism in healthy aging as assessed by in vivo magnetic resonance spectroscopy. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2010, Volume: 30, Issue:1 Topics: Adult; Aged; Aging; Aspartic Acid; Brain; Brain Chemistry; Female; Glucose Tolerance Test; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mitochondria	2010
Hyperhomocysteinemia selectively alters expression and stoichiometry of intermediate filament and induces glutamate- and calcium-mediated mechanisms in rat brain during development. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2010, Volume: 28, Issue:1 Topics: Aging; Animals; Brain; Calcium; Cerebral Cortex; Chronic Disease; Disease Models, Animal; Glutamic Acid; Hippocampus; Hyperhomocysteinemia; In Vitro Techniques; Intermediate Filament Proteins; Intermediate Filaments; Phosphorylation; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Ryanodine Receptor Calcium Release Channel	2010
The dual dopamine-glutamate phenotype of growing mesencephalic neurons regresses in mature rat brain. The Journal of comparative neurology, 2009, Dec-20, Volume: 517, Issue:6 Topics: Adrenergic Agents; Aging; Animals; Axons; Cell Count; Dopamine; Glutamic Acid; Mesencephalon; Neurons; Oxidopamine; Rats; RNA, Messenger; Synapses; Tyrosine 3-Monooxygenase; Vesicular Glutamate Transport Protein 2	2009
Properties of glutamatergic synapses in immature layer Vb pyramidal neurons: coupling of pre- and postsynaptic maturational states. Experimental brain research, 2010, Volume: 200, Issue:2 Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred C57BL; Models, Neurological; Patch-Clamp Techniques; Presynaptic Terminals; Probability; Pyramidal Cells; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex; Synapses	2010
Gamma-aminobutyric acid and glutamate differentially regulate intracellular calcium concentrations in mouse gonadotropin-releasing hormone neurons. Endocrinology, 2010, Volume: 151, Issue:1 Topics: Aging; Animals; Calcium; Calcium Signaling; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropin-Releasing Hormone; Intracellular Space; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Neurons; Osmolar Concentration; Receptors, AMPA	2010
The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic-ischemic brain damage in mice is mediated by CB(2) and adenosine receptors. Neurobiology of disease, 2010, Volume: 37, Issue:2 Topics: Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Aging; Animals; Animals, Newborn; Apoptosis; Brain; Cannabidiol; Caspase Inhibitors; Caspases; Cytoprotection; Disease Models, Animal; Down-Regulation; Glutamic Acid; Hypoxia-Ischemia, Brain; Inflammation Mediators; Interleukin-6; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neuroprotective Agents; Organ Culture Techniques; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Purinergic P1	2010
Promoting directional axon growth from neural progenitors grafted into the injured spinal cord. Journal of neuroscience research, 2010, May-01, Volume: 88, Issue:6 Topics: Aging; Animals; Axons; Brain-Derived Neurotrophic Factor; Cell Enlargement; Female; gamma-Aminobutyric Acid; Genetic Vectors; Glutamic Acid; Lentivirus; Nerve Regeneration; Neuroglia; Neurons; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Spinal Cord Injuries; Stem Cell Transplantation; Stem Cells	2010
Glutamate uptake shapes low-[Mg2+] induced epileptiform activity in juvenile rat hippocampal slices. Brain research, 2010, Jan-14, Volume: 1309 Topics: Aging; Animals; Aspartic Acid; CA3 Region, Hippocampal; Dicarboxylic Acids; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Epilepsy; Glutamic Acid; Hippocampus; Kainic Acid; Magnesium; Magnesium Deficiency; Male; Neurons; Neurotransmitter Transport Proteins; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells; Pyrrolidines; Rats; Rats, Wistar; Synaptic Transmission	2010
Effects of glyoxal or methylglyoxal on the metabolism of amino acids, lactate, glucose and acetate in the cerebral cortex of young and adult rats. Brain research, 2010, Feb-22, Volume: 1315 Topics: Acetates; Aging; Amino Acids; Animals; Carbon Dioxide; Central Nervous System Agents; Cerebral Cortex; Female; Glucose; Glutamic Acid; Glutamine; Glycine; Glyoxal; Lactic Acid; Lipid Metabolism; Male; Oxidation-Reduction; Protein Biosynthesis; Pyruvaldehyde; Rats; Rats, Wistar	2010
Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms. Proceedings of the National Academy of Sciences of the United States of America, 2009, Dec-29, Volume: 106, Issue:52 Topics: Aging; Animals; Astrocytes; Base Sequence; Brain; DNA Primers; Excitatory Amino Acid Transporter 2; Gene Expression; Glial Fibrillary Acidic Protein; Gliosis; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Mice; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Nuclear Proteins; Phenotype; Promoter Regions, Genetic; Recombinant Proteins; Sp1 Transcription Factor	2009
Dual cross-talk between nitric oxide and D-serine in astrocytes and neurons in the brain. Central nervous system agents in medicinal chemistry, 2009, Volume: 9, Issue:4 Topics: Aging; Animals; Animals, Newborn; Astrocytes; Brain; Brain Neoplasms; Cells, Cultured; Cytokines; Glutamic Acid; Neuronal Plasticity; Neurons; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Rats, Wistar; Receptor Cross-Talk; Serine; Stress, Physiological	2009
Deletion of Cav2.1(alpha1(A)) subunit of Ca2+-channels impairs synaptic GABA and glutamate release in the mouse cerebellar cortex in cultured slices. The European journal of neuroscience, 2009, Volume: 30, Issue:12 Topics: Aging; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Calcium Channels, P-Type; Calcium Channels, Q-Type; Cerebellar Cortex; Excitatory Postsynaptic Potentials; Exocytosis; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Inhibition; Neurons; Purkinje Cells; Synapses; Synaptic Transmission	2009
The combined effects on neuronal activation and blood-brain barrier permeability of time and n-3 polyunsaturated fatty acids in mice, as measured in vivo using MEMRI. NeuroImage, 2010, May-01, Volume: 50, Issue:4 Topics: Aging; Animals; Blood-Brain Barrier; Brain; Brain Mapping; Capillary Permeability; Chlorides; Cultured Milk Products; Diet; Fatty Acids, Omega-3; Fish Oils; Glutamic Acid; Magnetic Resonance Imaging; Male; Manganese Compounds; Mice; Mice, Inbred C57BL	2010
Metabolite concentrations in supraventricular white matter from teenage to early old age: A short echo time 1H magnetic resonance spectroscopy (MRS) study. Acta radiologica (Stockholm, Sweden : 1987), 2010, Volume: 51, Issue:3 Topics: Adolescent; Adult; Age Factors; Aged; Aging; Aspartic Acid; Biomarkers; Brain; Choline; Creatine; Female; Glutamic Acid; Glutamine; Humans; Inositol; Lipid Metabolism; Magnetic Resonance Spectroscopy; Male; Middle Aged; Myelin Sheath; Reference Values; Young Adult	2010
Deviant nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated Ca2+ signaling upon lysosome proliferation. The Journal of biological chemistry, 2010, Apr-30, Volume: 285, Issue:18 Topics: Aging; Animals; Calcium; Calcium Signaling; Cathepsins; Glutamic Acid; Hippocampus; Lysosomes; NADP; Neurodegenerative Diseases; Neurons; PC12 Cells; Protease Inhibitors; Rats; Rats, Sprague-Dawley	2010
Enhanced glutamatergic and decreased GABAergic synaptic appositions to GnRH neurons on proestrus in the rat: modulatory effect of aging. PloS one, 2010, Apr-14, Volume: 5, Issue:4 Topics: Aging; Animals; Diestrus; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropin-Releasing Hormone; Neurons; Presynaptic Terminals; Proestrus; Rats; Vesicular Glutamate Transport Protein 2; Vesicular Inhibitory Amino Acid Transport Proteins	2010
Changes in D-aspartate ion currents in the Aplysia nervous system with aging. Brain research, 2010, Jul-09, Volume: 1343 Topics: Aging; Animals; Aplysia; Cells, Cultured; Cellular Senescence; D-Aspartic Acid; Ganglia, Invertebrate; Glutamic Acid; Ion Channels; Models, Animal; Movement Disorders; Nervous System Physiological Phenomena; Neurons; Receptors, N-Methyl-D-Aspartate	2010
Addition of glutamate to serum-free culture promotes recovery of electrical activity in adult hippocampal neurons in vitro. Journal of neuroscience methods, 2010, Jul-15, Volume: 190, Issue:2 Topics: Aging; Animals; Cell Adhesion; Cell Culture Techniques; Cell Survival; Culture Media, Serum-Free; Extracellular Space; Glass; Glutamic Acid; Hippocampus; Immunohistochemistry; Membrane Potentials; Nerve Regeneration; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Time Factors	2010
Activity- and age-dependent modulation of GABAergic neurotransmission by system A-mediated glutamine uptake. Journal of neurochemistry, 2010, Volume: 114, Issue:3 Topics: Aging; Amino Acid Transport System A; Animals; Carrier Proteins; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Neural Inhibition; Neurotransmitter Agents; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Synaptic Transmission	2010
Reduction in glutamate uptake is associated with extrasynaptic NMDA and metabotropic glutamate receptor activation at the hippocampal CA1 synapse of aged rats. Aging cell, 2010, Volume: 9, Issue:5 Topics: Aging; Animals; Aspartic Acid; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Synapses; Synaptic Transmission; Tissue Distribution	2010
The BDNF Val66Met polymorphism impairs NMDA receptor-dependent synaptic plasticity in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Jun-30, Volume: 30, Issue:26 Topics: Aging; Animals; Brain-Derived Neurotrophic Factor; Female; Glutamic Acid; Hippocampus; Long-Term Potentiation; Long-Term Synaptic Depression; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuronal Plasticity; Neurons; Polymorphism, Genetic; Pyramidal Cells; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission	2010
A multivariate analysis of the effects of aging on glutamate, GABA and arginine metabolites in the rat vestibular nucleus. Hearing research, 2010, Oct-01, Volume: 269, Issue:1-2 Topics: Aging; Animals; Arginine; Cerebellum; Cluster Analysis; gamma-Aminobutyric Acid; Glutamic Acid; Male; Models, Animal; Multivariate Analysis; Rats; Rats, Sprague-Dawley; Spermidine; Spermine; Vestibular Nuclei	2010
The role of pannexin hemichannels in the anoxic depolarization of hippocampal pyramidal cells. Brain : a journal of neurology, 2010, Volume: 133, Issue:Pt 12 Topics: Adenosine Triphosphate; Aging; Animals; Brain Ischemia; CA1 Region, Hippocampal; Cell Hypoxia; Cell Membrane Permeability; Cell Separation; Coloring Agents; Connexins; Electrophysiological Phenomena; Extracellular Space; Glutamic Acid; Hippocampus; Ion Channels; Nerve Tissue Proteins; Patch-Clamp Techniques; Pyramidal Cells; Rats	2010
Proteolysis of calcineurin is increased in human hippocampus during mild cognitive impairment and is stimulated by oligomeric Abeta in primary cell culture. Aging cell, 2011, Volume: 10, Issue:1 Topics: Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Calcineurin; Calcineurin Inhibitors; Calcium; Calpain; Case-Control Studies; Cell Culture Techniques; Cell Fractionation; Cognition Disorders; Disease Progression; Enzyme Activation; Enzyme Inhibitors; Female; Glutamic Acid; Hippocampus; Humans; Male; Peptide Fragments; Rats; Receptors, N-Methyl-D-Aspartate; Retrospective Studies; Signal Transduction	2011
Application of umami taste stimulation to remedy hypogeusia based on reflex salivation. Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:11 Topics: Aged; Ageusia; Aging; Glutamic Acid; Humans; Parasympathomimetics; Saliva; Salivation; Taste; Taste Perception; Xerostomia	2010
Direct and indirect control of orexin/hypocretin neurons by glycine receptors. The Journal of physiology, 2011, Feb-01, Volume: 589, Issue:Pt 3 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Alanine; Animals; Animals, Newborn; Benzothiadiazines; Chloride Channels; Electrophysiological Phenomena; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Green Fluorescent Proteins; Hypothalamus; Intracellular Signaling Peptides and Proteins; Membrane Potentials; Mice; Mice, Transgenic; Neurons; Neuropeptides; Orexins; Patch-Clamp Techniques; Picrotoxin; Pyridazines; Receptors, GABA; Receptors, Glutamate; Receptors, Glycine; Strychnine; Synaptic Potentials	2011
Dopaminergic neurons of system x(c)⁻-deficient mice are highly protected against 6-hydroxydopamine-induced toxicity. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011, Volume: 25, Issue:4 Topics: Aging; Amino Acid Transport System y+; Animals; Corpus Striatum; Cystine; Dopamine; Glioma; Glutamic Acid; Glutathione; Mice; Mice, Knockout; Neurodegenerative Diseases; Neurons; Oxidopamine; Substantia Nigra; Tumor Cells, Cultured	2011
Determination of factors affecting glutamate concentrations in the whole blood of healthy human volunteers. Journal of neurosurgical anesthesiology, 2011, Volume: 23, Issue:1 Topics: Adolescent; Adult; Aged; Aging; Alanine Transaminase; Aspartate Aminotransferases; Blood Glucose; Brain Chemistry; Coffee; Eating; Female; Glutamic Acid; Humans; Male; Middle Aged; Reference Values; Sex Characteristics; Young Adult	2011
Age-dependent remodelling of ionotropic signalling in cortical astroglia. Aging cell, 2011, Volume: 10, Issue:3 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; Cell Communication; Excitatory Amino Acid Antagonists; Glutamic Acid; Mice; Mice, Transgenic; Neocortex; Neurons; Neurotransmitter Agents; Purinergic P2X Receptor Antagonists; Receptors, AMPA; Receptors, Ionotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P2X; Synaptic Potentials; Synaptic Transmission; Tissue Culture Techniques	2011
Region- and age-specific changes in glutamate transport in the AβPP23 mouse model for Alzheimer's disease. Journal of Alzheimer's disease : JAD, 2011, Volume: 24, Issue:2 Topics: Aging; Alzheimer Disease; Amino Acid Transport System X-AG; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glutamic Acid; Hippocampus; Humans; Mice; Mice, Transgenic; Mutation	2011
Comparison of metabolic profiling of cyanidin-3-O-galactoside and extracts from blueberry in aged mice. Journal of agricultural and food chemistry, 2011, Mar-09, Volume: 59, Issue:5 Topics: Aging; Animals; Anthocyanins; Blueberry Plants; Brain Chemistry; Choline; Fruit; Galactosides; gamma-Aminobutyric Acid; Glutamic Acid; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Metabolomics; Mice; Phosphorylcholine; Plant Extracts; Taurine	2011
Maturation of sleep homeostasis in developing rats: a role for preoptic area neurons. American journal of physiology. Regulatory, integrative and comparative physiology, 2011, Volume: 300, Issue:4 Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Electroencephalography; Glutamic Acid; Homeostasis; Models, Animal; Neurons; Preoptic Area; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Sleep; Sleep, REM; Wakefulness	2011
The effects of aging and genotype on NMDA receptor expression in growth hormone receptor knockout (GHRKO) mice. The journals of gerontology. Series A, Biological sciences and medical sciences, 2011, Volume: 66, Issue:6 Topics: Aging; Animals; Genotype; Glutamic Acid; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Receptors, N-Methyl-D-Aspartate; Receptors, Somatotropin; RNA, Messenger	2011
Changes in extracellular levels of glutamate in the nucleus accumbens after ethanol-induced behavioral sensitization in adolescent and adult mice. Alcohol (Fayetteville, N.Y.), 2011, Volume: 45, Issue:5 Topics: Aging; Animals; Behavior, Animal; Ethanol; Glutamic Acid; Male; Mice; Microdialysis; Motor Activity; Nucleus Accumbens	2011
Enhanced role of adenosine A(2A) receptors in the modulation of LTP in the rat hippocampus upon ageing. The European journal of neuroscience, 2011, Volume: 34, Issue:1 Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Aging; Animals; Electrophysiology; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Long-Term Potentiation; Male; Memory Disorders; N-Methylaspartate; Neuronal Plasticity; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Synaptic Transmission; Triazoles; Xanthines	2011
Activation of presynaptic GABAB receptors modulates GABAergic and glutamatergic inputs to the medial geniculate body. Hearing research, 2011, Volume: 280, Issue:1-2 Topics: Aging; Animals; Baclofen; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Geniculate Bodies; Glutamic Acid; Inhibitory Postsynaptic Potentials; Male; Models, Animal; Organophosphorus Compounds; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, GABA-B; Receptors, Presynaptic; Synaptic Transmission	2011
Multi-faced neuroprotective effects of Ginsenoside Rg1 in an Alzheimer mouse model. Biochimica et biophysica acta, 2012, Volume: 1822, Issue:2 Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Cerebellum; Cognition; Cognition Disorders; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Ginsenosides; Glutamic Acid; Humans; Learning; Memory; Mice; Mice, Transgenic; Neurons; Neuroprotective Agents; Phosphorylation	2012
Expression of equilibrative nucleoside transporter type 1 protein in elderly patients with schizophrenia. Neuroreport, 2012, Mar-07, Volume: 23, Issue:4 Topics: Aged; Aged, 80 and over; Aging; Equilibrative Nucleoside Transporter 1; Female; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Male; Middle Aged; Schizophrenia; Temporal Lobe	2012
Age and sex differences in impulsive action in rats: the role of dopamine and glutamate. Behavioural brain research, 2012, Apr-21, Volume: 230, Issue:1 Topics: Aging; Amphetamine; Analysis of Variance; Animals; Animals, Newborn; Choice Behavior; Conditioning, Operant; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Food Deprivation; Glutamic Acid; Impulsive Behavior; Male; Phenols; Piperidines; Pregnancy; Rats; Rats, Sprague-Dawley; Sex Characteristics; Water Deprivation	2012
Effect of chronic sleep restriction and aging on calcium signaling and apoptosis in the hippocampus of young and aged animals. Progress in neuro-psychopharmacology & biological psychiatry, 2012, Oct-01, Volume: 39, Issue:1 Topics: Aging; Animals; Apoptosis; bcl-2-Associated X Protein; Calcium Signaling; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Glutamic Acid; Hippocampus; Male; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Sleep Deprivation	2012
D₁-NMDA receptor interactions in the rat nucleus accumbens change during adolescence. Synapse (New York, N.Y.), 2012, Volume: 66, Issue:7 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Animals; Corpus Striatum; Dopamine; Dopamine Agonists; Glutamic Acid; N-Methylaspartate; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate	2012
Levels of C-peptide, body mass index and age, and their usefulness in classification of diabetes in relation to autoimmunity, in adults with newly diagnosed diabetes in Kronoberg, Sweden. European journal of endocrinology, 2012, Volume: 166, Issue:6 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Analysis of Variance; Area Under Curve; Autoantibodies; Autoimmunity; Biomarkers; Body Mass Index; C-Peptide; Carboxy-Lyases; Diabetes Mellitus; Diagnosis, Differential; Fasting; Female; Glutamic Acid; Humans; Incidence; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; ROC Curve; Statistics, Nonparametric; Sweden	2012
Cutaneous and electrically evoked glutamate signaling in the adult rat somatosensory system. Journal of neuroscience methods, 2012, Jul-15, Volume: 208, Issue:2 Topics: Afferent Pathways; Aging; Animals; Electric Stimulation; Evoked Potentials, Somatosensory; Glutamic Acid; Male; Physical Stimulation; Rats; Rats, Sprague-Dawley; Signal Transduction; Skin; Somatosensory Cortex	2012
Age-related changes in brain metabolites and cognitive function in APP/PS1 transgenic mice. Behavioural brain research, 2012, Nov-01, Volume: 235, Issue:1 Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Biomarkers; Choline; Creatine; Disease Models, Animal; Functional Neuroimaging; Glutamic Acid; Hippocampus; Inositol; Magnetic Resonance Spectroscopy; Maze Learning; Mice; Mice, Transgenic; Presenilin-1; Protons	2012
Glutamate and CO2 production from glutamine in incubated enterocytes of adult and very old rats. The Journal of nutritional biochemistry, 2013, Volume: 24, Issue:4 Topics: Aging; Animals; Carbon Dioxide; Enterocytes; Glutamic Acid; Glutamine; Rats; Rats, Wistar	2013
Polyphenols prevent ageing-related impairment in skeletal muscle mitochondrial function through decreased reactive oxygen species production. Experimental physiology, 2013, Volume: 98, Issue:2 Topics: Administration, Oral; Age Factors; Aging; Animals; Antioxidants; Ascorbic Acid; Electron Transport Chain Complex Proteins; Energy Metabolism; Gene Expression Regulation; Glutamic Acid; Malates; Male; Mitochondria, Muscle; Muscle, Skeletal; Oxidation-Reduction; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Polyphenols; Rats; Rats, Wistar; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA-Binding Proteins; RNA, Messenger; Sirtuin 1; Succinic Acid; Superoxide Dismutase; Time Factors; Transcription Factors	2013
Upregulation of calcium binding protein, S100A6, in activated astrocytes is linked to glutamate toxicity. Neuroscience, 2012, Dec-13, Volume: 226 Topics: Aging; Animals; Astrocytes; Axotomy; CA3 Region, Hippocampal; Cell Count; Cell Cycle Proteins; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Glutamic Acid; Hippocampus; Hypoglossal Nerve; Immunohistochemistry; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Neurons; Rats; Rats, Wistar; S100 Calcium Binding Protein A6; S100 Proteins; Tissue Fixation; Up-Regulation	2012
Morphine treatment in early life alters glutamate uptake in the spinal synaptosomes of adult rats. Neuroscience letters, 2012, Oct-31, Volume: 529, Issue:1 Topics: Aging; Animals; Animals, Newborn; Glutamic Acid; Male; Morphine; Neurons; Neurotransmitter Agents; Rats; Rats, Wistar; Spinal Cord; Synaptosomes	2012
Distinctive roles of PLD signaling elicited by oxidative stress in synaptic endings from adult and aged rats. Biochimica et biophysica acta, 2012, Volume: 1823, Issue:12 Topics: Aging; Animals; Cell Membrane; Diglycerides; GABA Plasma Membrane Transport Proteins; Glutamic Acid; Iron; Lipid Peroxidation; MAP Kinase Signaling System; Oxidative Stress; Phosphatidylcholines; Phospholipase D; Phosphorylation; Protein Kinase C-alpha; Rats; Rats, Wistar; Synaptosomes; TRPP Cation Channels	2012
Aralar mRNA and protein levels in neurons and astrocytes freshly isolated from young and adult mouse brain and in maturing cultured astrocytes. Neurochemistry international, 2012, Volume: 61, Issue:8 Topics: Aging; Animals; Aspartic Acid; Astrocytes; Brain; Cell Separation; Cells, Cultured; Cellular Senescence; Cytoplasm; Energy Metabolism; Female; Glutamic Acid; Lactic Acid; Male; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Membrane Transport Proteins; NAD; Nerve Tissue Proteins; Neurons; Oxidation-Reduction; Primary Cell Culture; Pyruvic Acid; Real-Time Polymerase Chain Reaction; RNA, Messenger	2012
Hippocampal glutamate level and glutamate aspartate transporter (GLAST) are up-regulated in senior rat associated with isoflurane-induced spatial learning/memory impairment. Neurochemical research, 2013, Volume: 38, Issue:1 Topics: Aging; Anesthetics, Inhalation; Animals; Blotting, Western; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Isoflurane; Learning Disabilities; Maze Learning; Memory Disorders; Microdialysis; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Up-Regulation	2013
Effect of CDP-choline on age-dependent modifications of energy- and glutamate-linked enzyme activities in synaptic and non-synaptic mitochondria from rat cerebral cortex. Neurochemistry international, 2012, Volume: 61, Issue:8 Topics: Aging; Animals; Catalysis; Citric Acid Cycle; Cytidine Diphosphate Choline; Enzyme Activation; Enzymes; Frontal Lobe; Glutamic Acid; Male; Mitochondria; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Random Allocation; Rats; Rats, Wistar; Synaptosomes	2012
In vivo glutamate measured with magnetic resonance spectroscopy: behavioral correlates in aging. Neurobiology of aging, 2013, Volume: 34, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Aging; Brain; Cognition; Female; Glutamic Acid; Humans; Male; Middle Aged; Tissue Distribution	2013
Glutamate changes in healthy young adulthood. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2013, Volume: 23, Issue:11 Topics: Adolescent; Adult; Aging; Cross-Sectional Studies; Female; Frontal Lobe; Functional Neuroimaging; Glutamic Acid; Health; Healthy Volunteers; Humans; Male; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Young Adult	2013
Neuroscience. Developmental refining of neuroglial signaling? Science (New York, N.Y.), 2013, Jan-11, Volume: 339, Issue:6116 Topics: Aging; Animals; Astrocytes; Calcium Signaling; Cerebral Cortex; Female; Glutamic Acid; Humans; Male; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate	2013
Glutamate-dependent neuroglial calcium signaling differs between young and adult brain. Science (New York, N.Y.), 2013, Jan-11, Volume: 339, Issue:6116 Topics: Adolescent; Aging; Animals; Astrocytes; Calcium; Calcium Signaling; Cerebral Cortex; Female; Glutamic Acid; Hippocampus; Humans; Male; Mice; Mice, Inbred C57BL; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Synaptic Transmission	2013
Longitudinal 1H MRS of rat forebrain from infancy to adulthood reveals adolescence as a distinctive phase of neurometabolite development. NMR in biomedicine, 2013, Volume: 26, Issue:6 Topics: Aging; Animals; Aspartic Acid; Dipeptides; Glutamic Acid; Inositol; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Prosencephalon; Rats; Rats, Sprague-Dawley; Taurine	2013
Altered expression and phosphorylation of N-methyl-D-aspartate receptors in piglet striatum after hypoxia-ischemia. Brain research. Molecular brain research, 2002, Jul-15, Volume: 104, Issue:1 Topics: Aging; Animals; Animals, Newborn; Antibody Specificity; Asphyxia Neonatorum; Corpus Striatum; Disease Models, Animal; Female; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Immunoblotting; Infant, Newborn; Male; Nerve Degeneration; Neurons; Neurotoxins; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Swine; Synaptic Transmission; Up-Regulation	2002
Impaired glutamate transport and glutamate-glutamine cycling: downstream effects of the Huntington mutation. Brain : a journal of neurology, 2002, Volume: 125, Issue:Pt 8 Topics: Aging; Animals; Biological Transport; Brain; Cerebral Cortex; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Female; Glutamic Acid; Glutamine; Humans; Huntingtin Protein; Huntington Disease; Immunohistochemistry; Male; Mice; Mice, Transgenic; Microdialysis; Mutation; Nerve Tissue Proteins; Nuclear Proteins	2002
Spillover of glutamate onto synaptic AMPA receptors enhances fast transmission at a cerebellar synapse. Neuron, 2002, Aug-01, Volume: 35, Issue:3 Topics: Aging; Animals; Cell Differentiation; Cerebellar Cortex; Dendrites; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Immunohistochemistry; Kynurenic Acid; Microscopy, Electron; Nerve Fibers; Organ Culture Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, AMPA; Synaptic Membranes; Synaptic Transmission; Time Factors	2002
Quantitative measurement of glutamate receptor subunit protein expression in the postnatal rat spinal cord. Brain research. Developmental brain research, 2002, Aug-30, Volume: 137, Issue:2 Topics: Aging; Animals; Animals, Newborn; Cell Differentiation; Down-Regulation; Glutamic Acid; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Cord Injuries; Synaptic Transmission; Up-Regulation	2002
Glutamate uptake in cultured astrocytes depends on age: a study about the effect of guanosine and the sensitivity to oxidative stress induced by H(2)O(2). Mechanisms of ageing and development, 2002, Volume: 123, Issue:10 Topics: Aging; Animals; Astrocytes; Cells, Cultured; Cerebral Cortex; Glial Fibrillary Acidic Protein; Glutamic Acid; Guanosine; Hydrogen Peroxide; Nerve Growth Factors; Oxidative Stress; Rats; Rats, Wistar; S100 Calcium Binding Protein beta Subunit; S100 Proteins	2002
Footshock stress alters early postnatal development of electrophysiological responses and caspase-3 activity in rat hippocampus. Neuroscience letters, 2002, Oct-31, Volume: 332, Issue:2 Topics: Aging; Animals; Animals, Newborn; Apoptosis; Caspase 3; Caspases; Electric Stimulation; Electrophysiology; Electroshock; Foot; Glutamic Acid; Hippocampus; In Vitro Techniques; Rats; Synaptic Transmission	2002
Muscarinic and nicotinic presynaptic modulation of EPSCs in the nucleus accumbens during postnatal development. Journal of neurophysiology, 2002, Volume: 88, Issue:6 Topics: Acetylcholine; Aging; Animals; Animals, Newborn; Cholinergic Agents; Cholinergic Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Muscarinic Antagonists; Nucleus Accumbens; Presynaptic Terminals; Rats; Receptors, Muscarinic; Receptors, Nicotinic	2002
Climbing fiber activation of metabotropic glutamate receptors on cerebellar purkinje neurons. Neuron, 2002, Dec-19, Volume: 36, Issue:6 Topics: Aging; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Calcium; Calcium Signaling; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Neural Pathways; Olivary Nucleus; Presynaptic Terminals; Purkinje Cells; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Synaptic Transmission; Up-Regulation	2002
[Deafness and aging: studies in experimental models]. Anales de la Real Academia Nacional de Medicina, 2002, Volume: 119, Issue:2 Topics: Aged; Aging; Animals; Deafness; Disease Models, Animal; Glutamic Acid; Hearing Disorders; Hearing Loss, Sensorineural; Humans; Mice; Mice, Inbred C57BL; Microscopy, Electron; Models, Biological; Noise; Organ of Corti; Presbycusis; Spain	2002
Age-dependent modulation of hippocampal excitability by KCNQ-channels. Epilepsy research, 2003, Volume: 53, Issue:1-2 Topics: Aging; Animals; Biosensing Techniques; Cortical Spreading Depression; Epilepsy, Benign Neonatal; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Membrane Potentials; Microdialysis; Neurons; Neurotransmitter Agents; Potassium; Potassium Channels; Rats; Rats, Wistar; Remission, Spontaneous; Synaptic Transmission	2003
Long-term potentiation is increased in the CA1 area of the hippocampus of APP(swe/ind) CRND8 mice. Neurobiology of disease, 2002, Volume: 11, Issue:3 Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Electrophysiology; Excitatory Postsynaptic Potentials; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; Genotype; Glutamic Acid; Hippocampus; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neural Inhibition; Neuronal Plasticity; Plaque, Amyloid; Synaptic Transmission	2002
Methylmercury increases glutamate release from brain synaptosomes and glutamate uptake by cortical slices from suckling rat pups: modulatory effect of ebselen. Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 73, Issue:1 Topics: Aging; Animals; Animals, Suckling; Azoles; Brain Chemistry; Cerebral Cortex; Glutamic Acid; In Vitro Techniques; Isoindoles; L-Lactate Dehydrogenase; Methylmercury Compounds; Nerve Tissue Proteins; Neuroprotective Agents; Organoselenium Compounds; Presynaptic Terminals; Rats; Rats, Wistar; Synaptosomes	2003
Age-related changes in neuronal glucose uptake in response to glutamate and beta-amyloid. Journal of neuroscience research, 2003, May-15, Volume: 72, Issue:4 Topics: Aging; Amyloid beta-Peptides; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Embryo, Mammalian; Fluorescent Antibody Technique; Glucose; Glucose Transporter Type 3; Glutamic Acid; Hippocampus; Male; Mitochondria; Monosaccharide Transport Proteins; Nerve Tissue Proteins; Neurons; Oligomycins; Protein Transport; Rats; Uncoupling Agents	2003
Postnatal development of mu-opioid receptors in the rat caudate-putamen nucleus parallels asymmetric synapse formation. Neuroscience, 2003, Volume: 118, Issue:3 Topics: Aging; Animals; Animals, Newborn; Caudate Nucleus; Cell Differentiation; Cerebral Cortex; Dendrites; Glutamic Acid; Immunohistochemistry; Male; Microscopy, Electron; Neural Pathways; Opioid Peptides; Presynaptic Terminals; Putamen; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Synaptic Membranes; Synaptic Transmission	2003
Functional differentiation of multiple climbing fiber inputs during synapse elimination in the developing cerebellum. Neuron, 2003, Jun-05, Volume: 38, Issue:5 Topics: Afferent Pathways; Aging; Animals; Animals, Newborn; Cell Differentiation; Cerebellar Cortex; Dendrites; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Presynaptic Terminals; Purkinje Cells; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Synaptic Vesicles	2003
Expression of vesicular glutamate transporter 1 in the mouse retina reveals temporal ordering in development of rod vs. cone and ON vs. OFF circuits. The Journal of comparative neurology, 2003, Oct-27, Volume: 465, Issue:4 Topics: Aging; Animals; Animals, Newborn; Carrier Proteins; Cell Differentiation; Glutamic Acid; Immunohistochemistry; Interneurons; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Neural Pathways; Presynaptic Terminals; Retina; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells; Synaptic Transmission; Synaptic Vesicles; Vesicular Glutamate Transport Protein 1; Vesicular Transport Proteins	2003
CHANGES IN GLUTAMIC ACID, GLUTAMINE, AND GAMMA-AMINOBUTYRIC ACID CONCENTRATIONS DURING POSTNATAL MATURATION OF THE CAT BRAIN. Acta medica Iugoslavica, 1964, Volume: 18 Topics: Aging; Aminobutyrates; Brain; Brain Chemistry; Cats; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Research	1964
METABOLISM OF PROPIONATE BY SHEEP LIVER. INTERRELATIONS OF PROPIONATE AND GLUTAMATE IN AGED MITOCHONDRIA. The Biochemical journal, 1965, Volume: 95 Topics: Acyl Coenzyme A; Aging; Amino Acids; Animals; Aspartic Acid; Carbon Dioxide; Citrates; Fatty Acids; Fumarates; Glutamates; Glutamic Acid; Ketoglutaric Acids; Liver; Malates; Mitochondria; Mitochondria, Liver; Oxaloacetates; Pharmacology; Propionates; Pyruvates; Research; Sheep; Sheep, Domestic; Succinates	1965
Lipid bound glutamic acid deficiency in aging arteriosclerotic subjects. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1960, Volume: 103 Topics: Aging; Biophysical Phenomena; Glutamates; Glutamic Acid; Humans; Lipids; Lipoproteins	1960
[The modulating role of essential and non-essential amino acids in organotypic tissue culture in rats of different ages]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2003, Volume: 89, Issue:5 Topics: Aging; Amino Acids; Amino Acids, Essential; Animals; Arginine; Asparagine; Cerebral Cortex; Culture Media; Glutamic Acid; Liver; Lysine; Organ Culture Techniques; Rats; Rats, Wistar; Spleen	2003
Widely expressed transcripts for chemokine receptor CXCR1 in identified glutamatergic, gamma-aminobutyric acidergic, and cholinergic neurons and astrocytes of the rat brain: a single-cell reverse transcription-multiplex polymerase chain reaction study. Journal of neuroscience research, 2003, Oct-15, Volume: 74, Issue:2 Topics: Acetylcholine; Aging; Animals; Animals, Newborn; Astrocytes; Brain; Cell Line; Cell Separation; Female; gamma-Aminobutyric Acid; Glutamic Acid; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-8A; Receptors, Interleukin-8B; RNA, Messenger	2003
Perinatal iron deficiency alters the neurochemical profile of the developing rat hippocampus. The Journal of nutrition, 2003, Volume: 133, Issue:10 Topics: Aging; Animals; Aspartic Acid; Body Weight; Brain; Brain Chemistry; Creatine; Ethanolamines; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Iron; Iron Deficiencies; Liver; Magnetic Resonance Spectroscopy; Male; Myocardium; Organ Size; Phosphocreatine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Taurine	2003
The role of adrenal hormones in the response of glutamine synthetase to fasting in adult and old rats. Clinical nutrition (Edinburgh, Scotland), 2003, Volume: 22, Issue:6 Topics: Adrenal Glands; Adrenalectomy; Age Factors; Aging; Analysis of Variance; Animals; Blotting, Northern; Fasting; Glucocorticoids; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Hormone Antagonists; Male; Mifepristone; Muscle, Skeletal; Rats; Rats, Wistar; RNA, Messenger	2003
Glutamate-induced differential mitochondrial response in young and adult rats. Neurochemistry international, 2004, Volume: 44, Issue:5 Topics: Adenosine Triphosphate; Aging; Animals; Calcium; Calcium Signaling; Cell Survival; Cerebral Cortex; Fluorescent Dyes; Fura-2; Glutamic Acid; Intracellular Membranes; L-Lactate Dehydrogenase; Microscopy, Fluorescence; Mitochondria; NAD; Neurons; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species	2004
The effects of IDRA 21, a positive modulator of the AMPA receptor, on delayed matching performance by young and aged rhesus monkeys. Neuropharmacology, 2004, Volume: 46, Issue:1 Topics: Aging; Animals; Behavior, Animal; Benzothiadiazines; Cell Line; Choice Behavior; Cognition; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Female; Glutamic Acid; Humans; Kidney; Macaca mulatta; Male; Membrane Potentials; Psychomotor Performance; Random Allocation; Reaction Time; Receptors, AMPA; Time Factors; Transfection	2004
Glutamate receptor binding in the frontal cortex and dorsal striatum of aged rats with impaired attentional set-shifting. The European journal of neuroscience, 2003, Volume: 18, Issue:12 Topics: Aging; Animals; Attention; Binding, Competitive; Cognition Disorders; Down-Regulation; Excitatory Amino Acid Agonists; Frontal Lobe; Glutamic Acid; Gyrus Cinguli; Maze Learning; Neostriatum; Prefrontal Cortex; Radioligand Assay; Rats; Rats, Long-Evans; Receptors, Glutamate; Set, Psychology; Space Perception; Tritium	2003
Prenatal infection obliterates glutamate-related protection against free hydroxyl radicals in neonatal rat brain. Journal of neuroscience research, 2004, Jan-01, Volume: 75, Issue:1 Topics: 2,3-Diketogulonic Acid; Aging; Animals; Animals, Newborn; Brain; Cell Membrane; Chromatography, High Pressure Liquid; Cyclohexanes; Cyclohexenes; Female; Fetal Diseases; Functional Laterality; Glutamic Acid; Hydroxyl Radical; Lipopolysaccharides; Male; Methoxyhydroxyphenylglycol; Neuroprotective Agents; Oxidative Stress; Piperidines; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Subcellular Fractions; Time Factors	2004
Age and monosodium glutamate treatment cause changes in the stimulation-induced [3H]-norepinephrine release from rat nucleus tractus solitarii-dorsal vagal nucleus slices. Life sciences, 2004, Feb-13, Volume: 74, Issue:13 Topics: Adrenergic alpha-Agonists; Aging; Animals; Animals, Newborn; Baclofen; GABA Agonists; Glutamic Acid; In Vitro Techniques; Norepinephrine; Rats; Rats, Wistar; Receptors, GABA-B; Sodium Glutamate; Solitary Nucleus; Tritium	2004
Glutamate transporters in platelets: EAAT1 decrease in aging and in Alzheimer's disease. Neurobiology of aging, 2004, Volume: 25, Issue:2 Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amino Acid Transport System X-AG; Blood Platelets; Blotting, Western; Brain; Case-Control Studies; Cell Line; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Female; Gene Expression; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Immunohistochemistry; Microscopy, Immunoelectron; Middle Aged; Monocytes; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Symporters	2004
Effect of DHEA glutamate release from synaptosomes of rats at different ages. Neurochemical research, 2004, Volume: 29, Issue:2 Topics: Aging; Animals; Brain; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Male; Osmolar Concentration; Potassium; Rats; Rats, Wistar; Synaptosomes	2004
S 18986, a positive modulator of AMPA receptors with cognition-enhancing properties, increases ACh release in the hippocampus of young and aged rat. Neuroscience letters, 2004, May-06, Volume: 361, Issue:1-3 Topics: Acetylcholine; Aging; Animals; Avoidance Learning; Benzothiadiazines; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Memory Disorders; Microdialysis; Nootropic Agents; Presynaptic Terminals; Rats; Rats, Wistar; Reaction Time; Receptors, AMPA; Scopolamine; Up-Regulation	2004
Hypoxic/ischaemic cell damage in cultured human NT-2 neurons. Brain research, 2004, Jun-11, Volume: 1011, Issue:1 Topics: Aging; Calcimycin; Calcium; Cell Death; Cell Line, Tumor; Cell Survival; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescein; Glutamic Acid; Humans; Hypoxia; Ionophores; Mitochondria; N-Methylaspartate; Neurons; Teratocarcinoma; Time Factors	2004
[Hyperexcitability CA1 neurons induced by brief episodes of hypoxia in hippocampal slices in rats of various age groups]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2004, Volume: 90, Issue:1 Topics: Action Potentials; Aging; Animals; Cell Hypoxia; Electric Stimulation; Epilepsy; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Kindling, Neurologic; Male; Neurons; Pyramidal Cells; Rats; Synaptic Transmission	2004
Impact of the selective estrogen receptor modulator, tamoxifen, on neuronal outgrowth and survival following toxic insults associated with aging and Alzheimer's disease. Experimental neurology, 2004, Volume: 188, Issue:2 Topics: Aging; Alzheimer Disease; Animals; Cell Differentiation; Cell Division; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Estradiol; Estrogens; Excitatory Amino Acids; Glutamic Acid; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Tamoxifen	2004
Quinolinic acid promotes seizures and decreases glutamate uptake in young rats: reversal by orally administered guanosine. Brain research, 2004, Aug-20, Volume: 1018, Issue:1 Topics: Administration, Oral; Aging; Animals; Animals, Newborn; Anticonvulsants; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Drug Interactions; Epilepsy; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Glutamic Acid; Guanosine; In Vitro Techniques; Injections, Intraventricular; Male; Neurons; Phenobarbital; Picrotoxin; Quinolinic Acid; Rats; Rats, Wistar	2004
Krebs cycle enzymes from livers of old mice are differentially regulated by caloric restriction. Experimental gerontology, 2004, Volume: 39, Issue:8 Topics: Aging; Animals; Aspartic Acid; Caloric Restriction; Citric Acid; Citric Acid Cycle; Glutamic Acid; Ketoglutaric Acids; Liver; Malates; Male; Mice; Mice, Inbred C57BL; Time Factors	2004
Developmental changes in release properties of the CA3-CA1 glutamate synapse in rat hippocampus. Journal of neurophysiology, 2004, Volume: 92, Issue:5 Topics: Aging; Animals; Calcium Channel Blockers; Dizocilpine Maleate; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Male; omega-Conotoxin GVIA; Pyramidal Cells; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses	2004
Effect of ageing and caloric restriction on specific markers of protein oxidative damage and membrane peroxidizability in rat liver mitochondria. Mechanisms of ageing and development, 2004, Volume: 125, Issue:8 Topics: Aging; Animals; Blotting, Western; Energy Intake; Fatty Acids; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Glycation End Products, Advanced; Lipid Peroxides; Male; Membrane Lipids; Mitochondria, Liver; Oxidative Stress; Proteins; Rats; Rats, Inbred BN	2004
Developmental expression of glutamate transporters and glutamate dehydrogenase in astrocytes of the postnatal rat hippocampus. Hippocampus, 2004, Volume: 14, Issue:8 Topics: Aging; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Astrocytes; Cell Differentiation; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Gene Expression Regulation, Developmental; Glutamate Dehydrogenase; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hippocampus; Male; Rats; Rats, Wistar; RNA, Messenger; Symporters; Synapses; Synaptic Transmission; Up-Regulation	2004
Kinetic characteristics of native gamma-glutamylcysteine ligase in the aging housefly, Musca domestica L. Biochemical and biophysical research communications, 2005, Jan-21, Volume: 326, Issue:3 Topics: Adenosine Triphosphate; Aging; Animals; Buthionine Sulfoximine; Cysteine; Feedback, Physiological; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Houseflies; Kinetics	2005
Age-related changes in the dynamics of potassium-evoked L-glutamate release in the striatum of Fischer 344 rats. Journal of neural transmission (Vienna, Austria : 1996), 2005, Volume: 112, Issue:1 Topics: Aging; Animals; Corpus Striatum; Glutamic Acid; Potassium; Rats; Rats, Inbred F344	2005
Postnatal developmental expressions of neurotransmitters and receptors in various brain stem nuclei of rats. Journal of applied physiology (Bethesda, Md. : 1985), 2005, Volume: 98, Issue:4 Topics: Aging; Animals; Animals, Newborn; Brain Stem; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Glutamic Acid; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, GABA-B; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Sensory Receptor Cells; Tissue Distribution	2005
Glutamatergic innervation of the heart initiates retrograde contractions in adult Drosophila melanogaster. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Jan-12, Volume: 25, Issue:2 Topics: Aging; Animals; Animals, Genetically Modified; Drosophila melanogaster; Electric Stimulation; Glutamic Acid; Heart; Immunohistochemistry; Myocardial Contraction; Neuropeptides; Receptors, AMPA; Synapses	2005
Effect of LTP-reinforcing paradigms on neurotransmitter release in the dentate gyrus of young and aged rats. Biochemical and biophysical research communications, 2005, Feb-18, Volume: 327, Issue:3 Topics: Acetylcholine; Aging; Animals; Aspartic Acid; Choline; Dentate Gyrus; Glutamic Acid; Glycine; Hydroxyindoleacetic Acid; Long-Term Potentiation; Microdialysis; Neurotransmitter Agents; Norepinephrine; Rats; Rats, Sprague-Dawley; Serotonin; Synaptic Transmission	2005
Time-matched pre- and postsynaptic changes of GABAergic synaptic transmission in the developing mouse superior colliculus. The Journal of physiology, 2005, Mar-15, Volume: 563, Issue:Pt 3 Topics: Action Potentials; Aging; Animals; Animals, Newborn; Cells, Cultured; Computer Simulation; Evoked Potentials; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Mice; Mice, Inbred C57BL; Models, Neurological; Presynaptic Terminals; Superior Colliculi; Synaptic Transmission	2005
Kainate/estrogen receptor involvement in rapid estradiol effects in vitro and intracellular signaling pathways. Endocrinology, 2005, Volume: 146, Issue:5 Topics: Aging; Animals; Arginine; Estradiol; Estrogen Receptor alpha; Female; Glutamic Acid; Gonadotropin-Releasing Hormone; Hypothalamus; Kinetics; Male; Median Eminence; Nitric Oxide; Preoptic Area; Rats; Rats, Wistar; Receptors, Estrogen; Receptors, Glutamate; Receptors, Kainic Acid; Signal Transduction	2005
Age-related glutamate and glutamine concentration changes in normal human brain: 1H MR spectroscopy study at 4 T. Neurobiology of aging, 2005, Volume: 26, Issue:5 Topics: Adult; Aged; Aging; Analysis of Variance; Aspartic Acid; Brain Chemistry; Creatine; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Motor Cortex; Protons; Statistics as Topic	2005
No evidence of mitochondrial respiratory dysfunction in OGG1-null mice deficient in removal of 8-oxodeoxyguanine from mitochondrial DNA. Free radical biology & medicine, 2005, Mar-15, Volume: 38, Issue:6 Topics: 8-Hydroxy-2'-Deoxyguanosine; Aging; Animals; Deoxyguanosine; DNA Glycosylases; DNA, Mitochondrial; Free Radicals; Glutamic Acid; Humans; Liver; Malates; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Mitochondria, Heart; Mitochondria, Liver; Myocardium; Oxidative Stress; Oxygen; Oxygen Consumption; Rats; Respiration Disorders; Time Factors	2005
Methylation of NMDA receptor NR2B gene as a function of age in the mouse brain. Neuroscience letters, 2005, Jun-03, Volume: 380, Issue:3 Topics: Aging; Animals; Cerebral Cortex; DNA Methylation; DNA-Cytosine Methylases; Genes; Genome; Glutamic Acid; Mice; Mice, Inbred C57BL; Receptors, N-Methyl-D-Aspartate; Up-Regulation	2005
Age-related calcium changes, oxyradical damage, caspase activation and nuclear condensation in hippocampal neurons in response to glutamate and beta-amyloid. Experimental gerontology, 2005, Volume: 40, Issue:5 Topics: Aging; Amyloid beta-Peptides; Animals; Apoptosis; Calcium; Caspase 3; Caspases; Cell Nucleus; Cells, Cultured; Enzyme Precursors; Glutamic Acid; Hippocampus; Neurons; Neurotoxins; Rats; Rats, Inbred F344; Reactive Oxygen Species	2005
Modification of dopaminergic markers expression in the striatum by neonatal exposure to glutamate during development. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2005, Volume: 23, Issue:4 Topics: Aging; Animals; Animals, Newborn; Biomarkers; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Female; Gene Expression Regulation, Developmental; Glutamic Acid; Injections, Subcutaneous; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Tissue Distribution; Tyrosine 3-Monooxygenase	2005
Prevention of age-related dysregulation of calcium dynamics by estrogen in neurons. Neurobiology of aging, 2006, Volume: 27, Issue:2 Topics: Aging; Amyloid beta-Peptides; Animals; Calcium; Calcium Signaling; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Estradiol; Fura-2; Glutamic Acid; Hippocampus; Male; Neurons; Rats	2006
Attenuation of preoptic area glutamate release correlates with reduced luteinizing hormone secretion in middle-aged female rats. Endocrinology, 2005, Volume: 146, Issue:10 Topics: Aging; Animals; Female; Glutamic Acid; Hypothalamus; Luteinizing Hormone; Microdialysis; Periodicity; Preoptic Area; Rats; Rats, Sprague-Dawley	2005
Proteomics analysis provides insight into caloric restriction mediated oxidation and expression of brain proteins associated with age-related impaired cellular processes: Mitochondrial dysfunction, glutamate dysregulation and impaired protein synthesis. Neurobiology of aging, 2006, Volume: 27, Issue:7 Topics: Aging; Animals; Brain; Caloric Restriction; Down-Regulation; Energy Metabolism; Enzyme Activation; Enzymes; Glutamic Acid; Male; Mitochondria; Nerve Growth Factors; Nerve Tissue Proteins; Neurodegenerative Diseases; Oxidative Stress; Proteomics; Rats; Rats, Wistar; Up-Regulation	2006
Expression profile of addicsin/GTRAP3-18 mRNA in mouse brain. Neuroscience letters, 2005, Oct-07, Volume: 386, Issue:3 Topics: Aging; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Brain; Brain Chemistry; Carrier Proteins; Cell Differentiation; Excitatory Amino Acid Transporter 3; Gene Expression Profiling; Gene Expression Regulation; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Heat-Shock Proteins; Male; Membrane Transport Proteins; Mice; Neuronal Plasticity; Neurons; Presynaptic Terminals; RNA, Messenger; Symporters; Up-Regulation	2005
Decreased whole-body and splanchnic glutamate metabolism in healthy elderly men and patients with chronic obstructive pulmonary disease in the postabsorptive state and in response to feeding. The Journal of nutrition, 2005, Volume: 135, Issue:9 Topics: Adult; Aged; Aging; Case-Control Studies; Eating; Glutamic Acid; Humans; Male; Middle Aged; Postprandial Period; Pulmonary Disease, Chronic Obstructive; Viscera	2005
High resolution 1H NMR-based metabolomics indicates a neurotransmitter cycling deficit in cerebral tissue from a mouse model of Batten disease. The Journal of biological chemistry, 2005, Dec-30, Volume: 280, Issue:52 Topics: Aging; Animals; Aspartic Acid; Brain; Cerebellum; Cerebral Cortex; Creatine; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Membrane Glycoproteins; Mice; Mice, Knockout; Models, Biological; Molecular Chaperones; Neuronal Ceroid-Lipofuscinoses; Neurotransmitter Agents; Phenotype; Spectrophotometry; Time Factors	2005
NMDA receptor-independent long-term depression correlates with successful aging in rats. Nature neuroscience, 2005, Volume: 8, Issue:12 Topics: Adaptation, Physiological; Aging; Animals; Cognition; Cognition Disorders; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Long-Term Synaptic Depression; Maze Learning; Memory Disorders; Neuronal Plasticity; Organ Culture Techniques; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Species Specificity; Synaptic Transmission; Type C Phospholipases	2005
Immunocytochemical analysis of D-serine distribution in the mammalian brain reveals novel anatomical compartmentalizations in glia and neurons. Glia, 2006, Volume: 53, Issue:4 Topics: Aging; Animals; Biomarkers; Brain; Brain Chemistry; Fixatives; Formaldehyde; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamic Acid; Glycine; Immunohistochemistry; Microscopy, Electron; Neuroglia; Neurons; Neurotransmitter Agents; Rats; Rats, Wistar; Receptors, Glutamate; Serine; Synaptic Vesicles; Tissue Fixation	2006
Differential effects of aging on NMDA receptors in the intermediate versus the dorsal hippocampus. Neurobiology of aging, 2006, Volume: 27, Issue:2 Topics: Age Factors; Aging; Analysis of Variance; Animals; Autoradiography; Gene Expression Regulation; Glutamic Acid; Hippocampus; In Situ Hybridization; Male; Mice; Mice, Inbred C57BL; Protein Subunits; Receptors, N-Methyl-D-Aspartate; Tritium	2006
Assessment of glutamate loss from the ganglion cell layer of young DBA/2J mice with glaucoma. American journal of veterinary research, 2006, Volume: 67, Issue:2 Topics: Aging; Animals; Glaucoma; Glutamic Acid; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Retinal Ganglion Cells	2006
Free amino acids in hearts of pediatric patients with congenital heart disease: the effects of cyanosis, age, and pathology. The Annals of thoracic surgery, 2006, Volume: 81, Issue:3 Topics: Aging; Alanine; Amino Acids; Biopsy; Child; Child, Preschool; Cyanosis; Glutamic Acid; Heart Defects, Congenital; Heart Ventricles; Humans; Infant; Infant, Newborn; Oxygen; Regression Analysis	2006
Neuroprotective role of neurokinin B (NKB) on beta-amyloid (25-35) induced toxicity in aging rat brain synaptosomes: involvement in oxidative stress and excitotoxicity. Biogerontology, 2006, Volume: 7, Issue:1 Topics: Aging; Amyloid beta-Peptides; Animals; Brain; Calcium Signaling; Drug Interactions; Female; Free Radical Scavengers; Glutamic Acid; In Vitro Techniques; Monoamine Oxidase; N-Methylaspartate; Neurokinin B; Neuroprotective Agents; Neurotransmitter Agents; Oxidative Stress; Peptide Fragments; Rats; Rats, Wistar; Superoxide Dismutase; Synaptosomes	2006
Effect of glutamate ingestion on whole-body glutamate turnover in healthy elderly and patients with chronic obstructive pulmonary disease. Nutrition (Burbank, Los Angeles County, Calif.), 2006, Volume: 22, Issue:5 Topics: Aged; Aging; Case-Control Studies; Dietary Supplements; Glutamic Acid; Glutamine; Health Status; Humans; Male; Middle Aged; Nitrogen Isotopes; Postprandial Period; Pulmonary Disease, Chronic Obstructive; Respiratory Function Tests	2006
GABAergic protection of hippocampal pyramidal neurons against glutamate insult: deficit in young animals compared to adults. Journal of neurophysiology, 2006, Volume: 96, Issue:1 Topics: Aging; Animals; Animals, Newborn; Calcium; Calcium Channels; Dendrites; Electrophysiology; Female; Gap Junctions; Glutamic Acid; Hypoxia-Ischemia, Brain; Male; Pyramidal Cells; Rats; Receptors, GABA-A; Receptors, Glutamate	2006
Functional maturation of CA1 synapses involves activity-dependent loss of tonic kainate receptor-mediated inhibition of glutamate release. Neuron, 2006, May-04, Volume: 50, Issue:3 Topics: Action Potentials; Aging; Animals; Cell Differentiation; Down-Regulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Long-Term Potentiation; Neural Inhibition; Neural Pathways; Organ Culture Techniques; Presynaptic Terminals; Rats; Receptors, G-Protein-Coupled; Receptors, Kainic Acid; Synaptic Transmission	2006
Synaptogenesis of the calyx of Held: rapid onset of function and one-to-one morphological innervation. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, May-17, Volume: 26, Issue:20 Topics: Aging; Animals; Animals, Newborn; Auditory Pathways; Auditory Perception; Cell Differentiation; Cochlear Nucleus; Electric Stimulation; Excitatory Postsynaptic Potentials; Glutamic Acid; Mice; Microscopy, Electron, Transmission; Neuronal Plasticity; Patch-Clamp Techniques; Presynaptic Terminals; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Rhombencephalon; Synaptic Membranes; Synaptic Transmission; Synaptic Vesicles; Time Factors	2006
Environmental enrichment promotes neurogenesis and changes the extracellular concentrations of glutamate and GABA in the hippocampus of aged rats. Brain research bulletin, 2006, Jun-15, Volume: 70, Issue:1 Topics: Aging; Analysis of Variance; Animals; Bromodeoxyuridine; Cell Count; Chromatography, High Pressure Liquid; Electrochemistry; Environment; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; Immunohistochemistry; Male; Microdialysis; Neurons; Rats; Rats, Wistar; Reaction Time	2006
Age-related effects of the neuromodulator D-serine on neurotransmission and synaptic potentiation in the CA1 hippocampal area of the rat. Journal of neurochemistry, 2006, Volume: 98, Issue:4 Topics: Aging; Animals; Dose-Response Relationship, Drug; Electrophysiology; Glutamic Acid; Glycine; Hippocampus; Long-Term Potentiation; Male; Nerve Net; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Serine; Synapses; Synaptic Transmission	2006
Expression of vesicular glutamate transporter 1 immunoreactivity in peripheral and central endings of trigeminal mesencephalic nucleus neurons in the rat. The Journal of comparative neurology, 2006, Sep-01, Volume: 498, Issue:1 Topics: Aging; Animals; Cholera Toxin; Glutamic Acid; Immunohistochemistry; Masseter Muscle; Microscopy, Electron, Transmission; Motor Neurons; Muscle Spindles; Neurons, Afferent; Presynaptic Terminals; Proprioception; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Synaptic Transmission; Trigeminal Nuclei; Vesicular Glutamate Transport Protein 1	2006
L-carnitine and alpha-lipoic acid improve age-associated decline in mitochondrial respiratory chain activity of rat heart muscle. The journals of gerontology. Series A, Biological sciences and medical sciences, 2006, Volume: 61, Issue:7 Topics: Aging; Analysis of Variance; Animals; Carnitine; Cell Respiration; Glutamic Acid; Hydroxybutyrates; Malates; Male; Mitochondria, Heart; Pyruvic Acid; Rats; Rats, Wistar; Succinic Acid; Thioctic Acid	2006
Electrophysiological mechanisms of delayed excitotoxicity: positive feedback loop between NMDA receptor current and depolarization-mediated glutamate release. Journal of neurophysiology, 2006, Volume: 96, Issue:5 Topics: Aging; Animals; Calcium; Calibration; Cell Death; Cells, Cultured; Data Interpretation, Statistical; Diagnostic Imaging; Electrophysiology; Feedback, Physiological; Female; Fluorescent Dyes; Glutamic Acid; Hippocampus; Indoles; Nerve Net; Patch-Clamp Techniques; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	2006
Reduced plasma membrane surface expression of GLAST mediates decreased glutamate regulation in the aged striatum. Neurobiology of aging, 2007, Volume: 28, Issue:11 Topics: Aging; Animals; Causality; Cell Membrane; Cell Survival; Corpus Striatum; Cytoprotection; Down-Regulation; Electrochemistry; Excitatory Amino Acid Transporter 1; Extracellular Fluid; Glutamic Acid; Hypoxia, Brain; Male; Neurons; Neurotoxins; Rats; Rats, Inbred F344; Stroke; Synaptic Transmission; Synaptosomes	2007
Differentiated effect of ageing on the enzymes of Krebs' cycle, electron transfer complexes and glutamate metabolism of non-synaptic and intra-synaptic mitochondria from cerebral cortex. Journal of neural transmission (Vienna, Austria : 1996), 2006, Volume: 113, Issue:11 Topics: Aging; Animals; Brain Chemistry; Cerebral Cortex; Citric Acid Cycle; Electron Transport Chain Complex Proteins; Glutamic Acid; Male; Mitochondria; Rats; Rats, Wistar; Synapses	2006
Plasticity of perisynaptic astroglia during synaptogenesis in the mature rat hippocampus. Glia, 2007, Jan-01, Volume: 55, Issue:1 Topics: Aging; Animals; Astrocytes; Cell Communication; Cell Differentiation; Cell Enlargement; Dendritic Spines; Glutamic Acid; Hippocampus; Image Cytometry; Male; Microscopy, Electron, Transmission; Neuronal Plasticity; Organ Culture Techniques; Presynaptic Terminals; Rats; Rats, Long-Evans; Synapses; Synaptic Membranes; Synaptic Transmission	2007
Glutamate-related gene expression changes with age in the mouse auditory midbrain. Brain research, 2007, Jan-05, Volume: 1127, Issue:1 Topics: Aging; Animals; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Transporter 1; Female; Gene Expression Profiling; Gene Expression Regulation; Glutamic Acid; Inferior Colliculi; Male; Mice; Mice, Inbred CBA; Neurotoxins; Oligonucleotide Array Sequence Analysis; Ornithine-Oxo-Acid Transaminase; Presbycusis; Proline; Up-Regulation	2007
An increase in in vivo release of LHRH and precocious puberty by posterior hypothalamic lesions in female rhesus monkeys (Macaca mulatta). American journal of physiology. Endocrinology and metabolism, 2007, Volume: 292, Issue:4 Topics: Aging; Animals; Circadian Rhythm; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropin-Releasing Hormone; Hypothalamic Diseases; Hypothalamus, Posterior; Macaca mulatta; Median Eminence; Menarche; Ovulation; Puberty, Precocious; Time Factors	2007
Recurrent seizures and the molecular maturation of hippocampal and neocortical glutamatergic synapses. Developmental neuroscience, 2007, Volume: 29, Issue:1-2 Topics: Aging; Animals; Cell Differentiation; Convulsants; Dendritic Spines; Disks Large Homolog 4 Protein; Down-Regulation; Epilepsy; Glutamic Acid; Guanylate Kinases; Hippocampus; Intracellular Signaling Peptides and Proteins; Learning Disabilities; Membrane Proteins; Mice; Mice, Inbred C57BL; Neocortex; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Recurrence; Synapses; Synaptic Transmission	2007
Postnatal switching of NMDA receptor subunits from NR2B to NR2A in rat facial motor neurons. The European journal of neuroscience, 2006, Volume: 24, Issue:11 Topics: Aging; Animals; Animals, Newborn; Cell Differentiation; Cells, Cultured; Excitatory Amino Acid Antagonists; Facial Nerve; Glutamic Acid; Immunohistochemistry; Membrane Potentials; Motor Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Rhombencephalon; RNA, Messenger; Synaptic Transmission; Up-Regulation	2006
Optical mapping of spatiotemporal emergence of functional synaptic connections in the embryonic chick olfactory pathway. Neuroscience, 2007, Feb-23, Volume: 144, Issue:4 Topics: Aging; Animals; Brain Mapping; Carbocyanines; Chick Embryo; Electric Stimulation; Excitatory Postsynaptic Potentials; Glutamic Acid; Neural Pathways; Olfactory Bulb; Olfactory Nerve; Olfactory Pathways; Optics and Photonics; Prosencephalon; Synapses; Synaptic Transmission; Time Factors	2007
Disynaptic amplification of metabotropic glutamate receptor 1 responses in the olfactory bulb. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Jan-03, Volume: 27, Issue:1 Topics: Aging; Animals; Cells, Cultured; Glutamic Acid; Mice; Mice, Knockout; Nerve Net; Neuronal Plasticity; Neurotransmitter Agents; Olfactory Bulb; Receptors, Metabotropic Glutamate; Smell; Synaptic Transmission	2007
Astrocytes aged in vitro show a decreased neuroprotective capacity. Journal of neurochemistry, 2007, Volume: 101, Issue:3 Topics: Aging; Animals; Animals, Newborn; Astrocytes; Cell Survival; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 1; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamic Acid; Heme Oxygenase-1; Hydrogen Peroxide; Nerve Growth Factors; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Reactive Oxygen Species; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Superoxide Dismutase; Superoxide Dismutase-1; Tyrosine	2007
Guanidinoacetate inhibits glutamate uptake in rat striatum of rats at different ages. Neurochemical research, 2007, Volume: 32, Issue:6 Topics: Aging; Animals; Glutamic Acid; Glycine; Microinjections; Neostriatum; Nerve Tissue Proteins; Rats; Rats, Wistar; Taurine	2007
Vesicular glutamate transporters VGLUT1 and VGLUT2 in the developing mouse barrel cortex. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2007, Volume: 25, Issue:2 Topics: Afferent Pathways; Aging; Animals; Animals, Newborn; Glutamic Acid; Immunohistochemistry; Male; Maxillary Nerve; Mechanoreceptors; Mice; Neurons; Neuropil; Somatosensory Cortex; Synaptic Transmission; Vesicular Glutamate Transport Protein 1; Vesicular Glutamate Transport Protein 2; Vibrissae	2007
NMDA-receptor blockade enhances cell apoptosis in the developing retina of the postnatal rat. The International journal of developmental biology, 2007, Volume: 51, Issue:2 Topics: Aging; Animals; Apoptosis; Dizocilpine Maleate; Glutamic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Retina; Superior Colliculi	2007
Altered excitability and distribution of NMDA receptor subunit proteins in cortical layers of rat pups following multiple perinatal seizures. Brain research, 2007, May-11, Volume: 1145 Topics: Action Potentials; Aging; Animals; Animals, Newborn; Cerebral Cortex; Electroencephalography; Epilepsy; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Immunohistochemistry; Kainic Acid; Male; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Up-Regulation	2007
Ebselen and diorganylchalcogenides decrease in vitro glutamate uptake by rat brain slices: prevention by DTT and GSH. Toxicology in vitro : an international journal published in association with BIBRA, 2007, Volume: 21, Issue:4 Topics: Aging; Animals; Antidotes; Azoles; Benzene Derivatives; Brain; Brain Chemistry; Cerebral Cortex; Chalcogens; Dithiothreitol; Glutamic Acid; Glutathione; In Vitro Techniques; Isoindoles; Male; Organometallic Compounds; Organoselenium Compounds; Rats; Rats, Wistar	2007
Simultaneous age-related depolarization of mitochondrial membrane potential and increased mitochondrial reactive oxygen species production correlate with age-related glutamate excitotoxicity in rat hippocampal neurons. Journal of neuroscience research, 2007, Volume: 85, Issue:5 Topics: Aging; Animals; Cells, Cultured; Cellular Senescence; Glutamic Acid; Hippocampus; Membrane Potential, Mitochondrial; Nerve Degeneration; Neurodegenerative Diseases; Neurons; Neurotoxins; Oxidative Phosphorylation; Oxidative Stress; Rats; Rats, Inbred F344; Reactive Oxygen Species	2007
The function of the glutamate-nitric oxide-cGMP pathway in brain in vivo and learning ability decrease in parallel in mature compared with young rats. Learning & memory (Cold Spring Harbor, N.Y.), 2007, Volume: 14, Issue:4 Topics: Aging; Animals; Brain; Cyclic GMP; Female; Glutamic Acid; Immunoblotting; Male; Maze Learning; Microdialysis; N-Methylaspartate; Nitric Oxide; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate	2007
Increased vulnerability of hippocampal neurons with age in culture: temporal association with increases in NMDA receptor current, NR2A subunit expression and recruitment of L-type calcium channels. Brain research, 2007, Jun-02, Volume: 1151 Topics: Aging; Animals; Calcium; Calcium Channels, L-Type; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Embryo, Mammalian; Female; Gene Expression; Glutamic Acid; Hippocampus; L-Lactate Dehydrogenase; Membrane Potentials; N-Methylaspartate; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	2007
Spatial and temporal expression of RP58, a novel zinc finger transcriptional repressor, in mouse brain. The Journal of comparative neurology, 2007, Jun-20, Volume: 502, Issue:6 Topics: Aging; Animals; Brain; Cell Differentiation; Cell Movement; Cell Proliferation; Gene Expression Regulation, Developmental; Glutamate Decarboxylase; Glutamic Acid; In Situ Hybridization; Isoenzymes; Mice; Mice, Inbred C57BL; Neurons; Polymerase Chain Reaction; Repressor Proteins; RNA, Messenger; Stem Cells; Time Factors; Transcription Factors; Up-Regulation; Vesicular Glutamate Transport Protein 1; Zinc Fingers	2007
Early music exposure modifies GluR2 protein expression in rat auditory cortex and anterior cingulate cortex. Neuroscience letters, 2007, Jun-13, Volume: 420, Issue:2 Topics: Acoustic Stimulation; Aging; Animals; Animals, Newborn; Auditory Cortex; Auditory Perception; Glutamic Acid; Gyrus Cinguli; Music; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Synaptic Transmission; Time; Up-Regulation	2007
Age-related declines in a two-day reference memory task are associated with changes in NMDA receptor subunits in mice. BMC neuroscience, 2007, Jun-22, Volume: 8 Topics: Aging; Animals; Brain; Glutamic Acid; Hippocampus; Male; Maze Learning; Memory; Memory Disorders; Mice; Mice, Inbred C57BL; Neuropsychological Tests; Prefrontal Cortex; Presynaptic Terminals; Protein Subunits; Qa-SNARE Proteins; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Synaptosomes	2007
Repeated treatment with N-methyl-d-aspartate antagonists in neonatal, but not adult, rats causes long-term deficits of radial-arm maze learning. Brain research, 2007, Sep-12, Volume: 1169 Topics: Aging; Animals; Animals, Newborn; Brain; Brain Chemistry; Dizocilpine Maleate; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Exploratory Behavior; Female; Glutamic Acid; Learning Disabilities; Male; Maze Learning; Memory; Memory Disorders; Pipecolic Acids; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Time	2007
Rapid bidirectional switching of synaptic NMDA receptors. Neuron, 2007, Sep-06, Volume: 55, Issue:5 Topics: Aging; Animals; Brain; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Long-Term Potentiation; Male; Organ Culture Techniques; Piperidines; Protein Subunits; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Time Factors	2007
Role of maternal corticosterone in the development and maturation of the aminoacidergic systems of the rat brain. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2007, Volume: 25, Issue:7 Topics: Aging; Amino Acids; Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Corticosterone; Electrochemistry; Enzyme Inhibitors; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Male; Metyrapone; Pregnancy; Rats; Rats, Wistar; Sex Characteristics	2007
Amperometric measures of age-related changes in glutamate regulation in the cortex of rhesus monkeys. Experimental neurology, 2007, Volume: 208, Issue:2 Topics: Aging; Animals; Dose-Response Relationship, Drug; Electrophysiology; Equipment Design; Extracellular Fluid; Female; Glutamic Acid; Macaca mulatta; Microelectrodes; Motor Cortex; Potassium; Solutions	2007
Mechanism of age-dependent susceptibility and novel treatment strategy in glutaric acidemia type I. The Journal of clinical investigation, 2007, Volume: 117, Issue:11 Topics: Aging; Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic, Inborn; Child; Diet; Disease Models, Animal; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glucose; Glutamic Acid; Glutarates; Glutaryl-CoA Dehydrogenase; Homoarginine; Humans; Lysine; Mice; Mice, Knockout; Mitochondria; Neurons; Nuclear Magnetic Resonance, Biomolecular; Tryptophan	2007
Reduced activity of cortico-striatal fibres in the R6/2 mouse model of Huntington's disease. Neuroreport, 2007, Dec-03, Volume: 18, Issue:18 Topics: Aging; Animals; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Down-Regulation; Extracellular Fluid; Female; Gene Expression Regulation; Glutamic Acid; Huntington Disease; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microdialysis; Neural Pathways; Synaptic Transmission	2007
Age-related decrease in stimulated glutamate release and vesicular glutamate transporters in APP/PS1 transgenic and wild-type mice. Journal of neurochemistry, 2008, Volume: 105, Issue:3 Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Astrocytes; Brain; Disease Models, Animal; Down-Regulation; Glial Fibrillary Acidic Protein; Gliosis; Glutamic Acid; Humans; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Plaque, Amyloid; Presenilin-1; Synaptic Transmission; Vesicular Glutamate Transport Protein 1	2008
Profile of glutamate uptake and cellular viability in hippocampal slices exposed to oxygen and glucose deprivation: developmental aspects and protection by guanosine. Brain research, 2008, Jan-10, Volume: 1188 Topics: Aging; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Biological Transport, Active; Brain Infarction; Cell Survival; Energy Metabolism; Glutamic Acid; Guanosine; Hippocampus; Hypoxia-Ischemia, Brain; Male; Neurons; Neuroprotective Agents; Organ Culture Techniques; Rats; Rats, Wistar	2008
Developmental exposure to polychlorinated biphenyls PCB153 or PCB126 impairs learning ability in young but not in adult rats. The European journal of neuroscience, 2008, Volume: 27, Issue:1 Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Cerebellum; Cyclic GMP; Embryo, Mammalian; Female; Glutamic Acid; Learning Disabilities; Maze Learning; Nitric Acid; Polychlorinated Biphenyls; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar	2008
Early maturation of GABAergic synapses in mouse retinal ganglion cells. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2008, Volume: 26, Issue:2 Topics: Aging; Animals; Cell Differentiation; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Inhibitory Postsynaptic Potentials; Mice; Mice, Inbred C57BL; Neural Inhibition; Neural Pathways; Organ Culture Techniques; Patch-Clamp Techniques; Retina; Retinal Ganglion Cells; Synapses; Synaptic Transmission; Time Factors	2008
Low striatal glutamate levels underlie cognitive decline in the elderly: evidence from in vivo molecular spectroscopy. Cerebral cortex (New York, N.Y. : 1991), 2008, Volume: 18, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Aging; Cerebellum; Cognition; Cognition Disorders; Corpus Striatum; Efferent Pathways; Female; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Memory, Short-Term; Neuropsychological Tests; Prefrontal Cortex; Young Adult	2008
The pool of fast releasing vesicles is augmented by myosin light chain kinase inhibition at the calyx of Held synapse. Journal of neurophysiology, 2008, Volume: 99, Issue:4 Topics: Actins; Action Potentials; Aging; Animals; Calcium; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Fluorescent Dyes; Fura-2; Glutamic Acid; In Vitro Techniques; Ion Channels; Mice; Mice, Inbred C57BL; Myosin-Light-Chain Kinase; Myosins; Neuronal Plasticity; Receptors, Presynaptic; Synapses; Synaptic Vesicles	2008
White matter vulnerability to ischemic injury increases with age because of enhanced excitotoxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Feb-06, Volume: 28, Issue:6 Topics: Aging; Animals; Calcium; Excitatory Amino Acid Agents; Glutamic Acid; Male; Mice; Nerve Fibers, Myelinated; Optic Neuropathy, Ischemic	2008
Impaired muscarinic regulation of excitatory synaptic transmission in the APPswe/PS1dE9 mouse model of Alzheimer's disease. European journal of pharmacology, 2008, Mar-31, Volume: 583, Issue:1 Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Blotting, Western; Cholinesterase Inhibitors; Disease Models, Animal; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Mice; Mice, Transgenic; Muscarinic Antagonists; Nicotinic Antagonists; Patch-Clamp Techniques; Physostigmine; Presenilin-1; Receptors, Muscarinic; Receptors, Nicotinic; Synaptic Transmission	2008
Memantine decreases hippocampal glutamate levels: a magnetic resonance spectroscopy study. Progress in neuro-psychopharmacology & biological psychiatry, 2008, May-15, Volume: 32, Issue:4 Topics: Adult; Aged; Aging; Alzheimer Disease; Cognition Disorders; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Memantine	2008
Rapid eye movement sleep deprivation decreases long-term potentiation stability and affects some glutamatergic signaling proteins during hippocampal development. Neuroscience, 2008, Apr-22, Volume: 153, Issue:1 Topics: Aging; Animals; Animals, Newborn; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disks Large Homolog 4 Protein; Down-Regulation; Glutamic Acid; Hippocampus; Intracellular Signaling Peptides and Proteins; Long-Term Potentiation; Male; Membrane Proteins; Protein Subunits; Rats; Rats, Long-Evans; Receptors, Glutamate; Signal Transduction; Sleep Deprivation; Sleep, REM; Synaptic Transmission	2008
Neonatal isolation delays the developmental decline of long-term depression in the CA1 region of rat hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:12 Topics: Aging; Aniline Compounds; Animals; Corticotropin-Releasing Hormone; Electric Stimulation; Glutamic Acid; Hippocampus; Long-Term Synaptic Depression; Maternal Deprivation; Neurons; Neurosecretory Systems; Organ Culture Techniques; Patch-Clamp Techniques; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Social Isolation; Stress, Psychological; Synaptic Transmission; Time Factors; Up-Regulation	2008
Extensive neuroadaptive changes in cortical gene-transcript expressions of the glutamate system in response to repeated intermittent MDMA administration in adolescent rats. BMC neuroscience, 2008, Apr-17, Volume: 9 Topics: Adaptation, Physiological; Adrenergic Uptake Inhibitors; Age Factors; Aging; Amphetamine-Related Disorders; Animals; Brain; Brain Chemistry; Cerebral Cortex; Drug Administration Schedule; Gene Expression Regulation; Glutamic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Synaptic Transmission; Vesicular Glutamate Transport Proteins	2008
Age-related decreases in NAD(P)H and glutathione cause redox declines before ATP loss during glutamate treatment of hippocampal neurons. Journal of neuroscience research, 2008, Aug-01, Volume: 86, Issue:10 Topics: Adenosine Triphosphate; Aging; Animals; Calcium; Chromatography, High Pressure Liquid; Electron Transport Complex I; Flavin-Adenine Dinucleotide; Glutamic Acid; Glutathione; Hippocampus; Mitochondria; NADP; Neurons; Oxidation-Reduction; Rats; Rats, Inbred F344	2008
Ontogeny of receptor binding sites for [3H]glutamic acid and [3H]kainic acid in the rat cerebellum. Journal of neurochemistry, 1981, Volume: 37, Issue:2 Topics: Aging; Animals; Animals, Newborn; Cerebellum; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Pyrrolidines; Rats; Receptors, Cell Surface; Receptors, Glutamate; Receptors, Kainic Acid	1981
Glutamate binding in the rat cerebral cortex during ontogeny. Brain research, 1981, Volume: 254, Issue:3 Topics: Aging; Amino Acids; Animals; Cell Membrane; Cerebral Cortex; Glutamates; Glutamic Acid; Kinetics; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Glutamate; Receptors, Neurotransmitter; Sodium	1981
Decline in respiratory control ratio of rat liver mitochondria in old age. Mechanisms of ageing and development, 1981, Volume: 17, Issue:3 Topics: Adenosine Diphosphate; Aging; Animals; Energy Metabolism; Glutamates; Glutamic Acid; Malates; Mitochondria, Liver; Oxygen Consumption; Rats; Succinates; Succinic Acid	1981
Specific and non-specific effects of neuro-excitatory amino acids on learning and other behaviours in the chicken. Behavioural brain research, 1982, Volume: 4, Issue:1 Topics: Aggression; Aging; Animals; Aspartic Acid; Behavior, Animal; Chickens; Copulation; Glutamates; Glutamic Acid; Habituation, Psychophysiologic; Humans; Kainic Acid; Learning; N-Methylaspartate; Pattern Recognition, Visual; Pyrrolidines; Visual Perception	1982
Glutamate in schizophrenics and healthy controls. Archiv fur Psychiatrie und Nervenkrankheiten, 1982, Volume: 231, Issue:3 Topics: Adult; Aging; Antipsychotic Agents; Female; Glutamates; Glutamic Acid; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia, Paranoid	1982
Age-related changes in the glutamate metabolism of cerebral cortical slices from rats. Neurochemical research, 1982, Volume: 7, Issue:6 Topics: Aging; Animals; Aspartic Acid; Carbon Dioxide; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Male; Rats; Rats, Inbred Strains	1982
Protein and taurine of maternal diets during the mouse neonatal period: permanent effects on cerebellar--brainstem amino acid levels in mature offspring. Neurochemical research, 1982, Volume: 7, Issue:8 Topics: Aging; Amino Acids; Animals; Animals, Newborn; Brain Stem; Cerebellum; Dietary Proteins; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Lactation; Mice; Pregnancy; Protein Deficiency; Taurine	1982
Sulfur amino acid metabolism in the developing rhesus monkey brain: interrelationship of taurine and glutamate. Neurochemical research, 1982, Volume: 7, Issue:9 Topics: Aging; Amino Acids; Animals; Animals, Newborn; Female; Fetus; Glutamates; Glutamic Acid; Macaca mulatta; Mitochondria; Occipital Lobe; Pregnancy; Synaptosomes; Taurine	1982
Effects of free fatty acids, ethanol and development on gamma-aminobutyric acid and glutamate fluxes in rat nerve endings. Biochemical pharmacology, 1982, Dec-15, Volume: 31, Issue:24 Topics: Aging; Animals; Chemical Phenomena; Chemistry, Physical; Ethanol; Fatty Acids, Nonesterified; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Kinetics; Nerve Endings; Rats; Temperature; Thermodynamics	1982
Glutamate uptake into cerebral cortex slices is reduced in the presence of a gamma-glutamyl transpeptidase inhibitor. Experientia, 1983, Jan-15, Volume: 39, Issue:1 Topics: Aging; Animals; Biological Transport, Active; Borates; Cerebral Cortex; gamma-Glutamyltransferase; Glutamates; Glutamic Acid; Male; Mice; Mice, Inbred Strains; Serine; Sodium	1983
Biochemical development of the human brain. III. Benzodiazepine receptors, free gamma-aminobutyrate (GABA) and other amino acids. Journal of neuroscience research, 1982, Volume: 8, Issue:4 Topics: Adult; Aged; Aging; Amino Acids; Aspartic Acid; Brain; Cerebellum; Female; Flunitrazepam; Frontal Lobe; gamma-Aminobutyric Acid; Gestational Age; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Glutamine; Humans; Infant; Infant, Newborn; Kinetics; Middle Aged; Pregnancy; Receptors, Cell Surface; Receptors, GABA-A	1982
Classification and properties of acidic amino acid receptors in hippocampus. III. Supersensitivity during the postnatal period and following denervation. Molecular pharmacology, 1983, Volume: 24, Issue:2 Topics: Aging; Animals; Biological Transport; Denervation; Glutamates; Glutamic Acid; Hippocampus; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Sodium	1983
Excitotoxic amino acids as neuroendocrine research tools. Methods in enzymology, 1983, Volume: 103 Topics: Aging; Amino Acids; Animals; Aspartic Acid; Axons; Blood-Brain Barrier; Brain; Glutamates; Glutamic Acid; Neurotoxins; Organ Specificity; Structure-Activity Relationship	1983
Kainate-glutamate interactions in rat cerebellar slices. Neuroscience, 1984, Volume: 11, Issue:1 Topics: Aging; Animals; Cell Survival; Cerebellum; Cyclic GMP; Drug Interactions; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Pyrrolidines; Rats; Rats, Inbred Strains	1984
Metabolism of the glutamate group of amino acids in rat brain as a function of age. Mechanisms of ageing and development, 1984, Volume: 24, Issue:2 Topics: Aging; Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Energy Metabolism; Enzymes; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Male; Rats; Rats, Inbred Strains	1984
High-affinity uptake of neurotransmitters in rat neostriatum: effects of aging. Journal of neurochemistry, 1984, Volume: 43, Issue:6 Topics: Aging; Animals; Caudate Nucleus; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; Neurotransmitter Agents; Putamen; Rats; Rats, Inbred Strains	1984
The GABA/benzodiazepine receptor complex in the nervous system of a hypertensive strain of rat. Neurochemical research, 1984, Volume: 9, Issue:8 Topics: Aging; Animals; Brain; Cerebellum; Cerebral Cortex; Flunitrazepam; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, GABA-A; Synaptic Membranes	1984
Effect of hyperbaric oxygen on 2-deoxy-D-glucose and L-glutamate transport in rat cortical synaptosomes. Neurochemical research, 1984, Volume: 9, Issue:8 Topics: Aging; Animals; Biological Transport; Cerebral Cortex; Deoxy Sugars; Deoxyglucose; Glutamates; Glutamic Acid; Hyperbaric Oxygenation; Kinetics; Male; Rats; Synaptosomes	1984
[Effect of potassium glutamate on water-electrolyte metabolism and acid-base balance of persons of different ages]. Vrachebnoe delo, 1984, Issue:8 Topics: Acid-Base Equilibrium; Adult; Aged; Aging; Arteriosclerosis; Cardiac Complexes, Premature; Chlorine; Glutamates; Glutamic Acid; Humans; Potassium; Sodium; Time Factors; Water-Electrolyte Balance	1984
Development of glycinergic and glutamatergic synaptic transmission in the auditory brainstem of perinatal rats. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1995, Volume: 15, Issue:10 Topics: Aging; Animals; Auditory Pathways; Brain Stem; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Male; Neurons; Olivary Nucleus; Rats; Rats, Sprague-Dawley; Strychnine; Synaptic Transmission	1995
Endogenous excitatory amino acid release from brain slices and astrocyte cultures evoked by trimethyltin and other neurotoxic agents. Neurochemical research, 1995, Volume: 20, Issue:7 Topics: Aging; Animals; Aspartic Acid; Astrocytes; Brain; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acids; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; In Vitro Techniques; Male; Neurotoxins; Ouabain; Potassium Chloride; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Sodium Glutamate; Taurine; Trimethyltin Compounds; Veratrine	1995
Effects of long-term treatment with a monoamine oxidase B inhibitor, selegeline (L-deprenyl), on amino acid transmitter systems in the ageing rat brain. Proceedings of the Western Pharmacology Society, 1995, Volume: 38 Topics: Aging; Animals; Brain Chemistry; Dizocilpine Maleate; Glutamic Acid; In Vitro Techniques; Male; Membranes; Monoamine Oxidase Inhibitors; Nerve Tissue Proteins; Neurotransmitter Agents; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Selegiline	1995
The role of hyperthermia in amphetamine's interactions with NMDA receptors, nitric oxide, and age to produce neurotoxicity. Annals of the New York Academy of Sciences, 1995, Sep-15, Volume: 765 Topics: Aging; Amphetamine; Animals; Arginine; Brain; Dizocilpine Maleate; Fever; Glutamic Acid; Haloperidol; Methamphetamine; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Receptors, N-Methyl-D-Aspartate; Stereoisomerism	1995
Effect of ageing on tissue levels of amino acids involved in the nitric oxide pathway in rat brain. Journal of neural transmission. General section, 1993, Volume: 94, Issue:1 Topics: Aging; Amino Acid Oxidoreductases; Amino Acids; Animals; Arginine; Aspartic Acid; Brain Chemistry; Citrulline; Glutamates; Glutamic Acid; Male; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Rats; Rats, Wistar	1993
Synaptic activation of NF-kappa B by glutamate in cerebellar granule neurons in vitro. Proceedings of the National Academy of Sciences of the United States of America, 1995, Sep-26, Volume: 92, Issue:20 Topics: Aging; Animals; Brain; Cell Division; Cell Nucleus; Cells, Cultured; Cerebellum; Dendrites; Fluorescent Antibody Technique; Glutamic Acid; Immunohistochemistry; Mice; Neurons; NF-kappa B; Purkinje Cells; Synapses; Transcription Factor RelA	1995
Mitochondrial ATP production rate in 55 to 73-year-old men: effect of endurance training. Acta physiologica Scandinavica, 1995, Volume: 154, Issue:2 Topics: 3-Hydroxyacyl CoA Dehydrogenases; Adenosine Triphosphate; Aged; Aging; Carnitine O-Palmitoyltransferase; Citrate (si)-Synthase; Glutamic Acid; Hexokinase; Humans; Malates; Male; Middle Aged; Mitochondria, Muscle; Muscle, Skeletal; Palmitoylcarnitine; Physical Endurance; Pyruvates; Pyruvic Acid	1995
Age-dependent neurotoxicity of striatal lesions produced by aminooxyacetic acid: quantitative in vitro 1H NMR spectroscopic studies. Journal of neurochemistry, 1995, Volume: 65, Issue:3 Topics: Aging; Alanine; Animals; Aspartic Acid; Corpus Striatum; Creatine; Energy Metabolism; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycine; In Vitro Techniques; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Mitochondria; Rats; Rats, Sprague-Dawley	1995
Preservation of inner retinal responses in the aged Royal College of Surgeons rat. Evidence against glutamate excitotoxicity in photoreceptor degeneration. Investigative ophthalmology & visual science, 1995, Volume: 36, Issue:10 Topics: Aging; Animals; Dark Adaptation; Electroretinography; Female; Glutamic Acid; Male; Neurons; Photoreceptor Cells; Rats; Rats, Mutant Strains; Retina; Retinal Degeneration; Sensory Thresholds; Signal Transduction	1995
Prenatal exposure of rats to ammonia impairs NMDA receptor function and affords delayed protection against ammonia toxicity and glutamate neurotoxicity. Journal of neuropathology and experimental neurology, 1995, Volume: 54, Issue:5 Topics: Aging; Ammonia; Animals; Aspartate Aminotransferases; Cells, Cultured; Cerebellum; Diet; Dizocilpine Maleate; Female; Glutamic Acid; L-Lactate Dehydrogenase; Lactation; N-Methylaspartate; Neurons; Neurotoxins; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate	1995
Development of dopamine and N-methyl-D-aspartate systems in rat brain: the effect of prenatal phencyclidine exposure. Brain research. Developmental brain research, 1993, May-21, Volume: 73, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Corpus Striatum; Dopamine; Female; Frontal Lobe; Glutamates; Glutamic Acid; Hydroxyindoleacetic Acid; Male; Methamphetamine; N-Methylaspartate; Phencyclidine; Pipecolic Acids; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley	1993
Calcium signaling of glial cells along mammalian axons. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1993, Volume: 13, Issue:10 Topics: Action Potentials; Adenosine; Adenosine Triphosphate; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aniline Compounds; Animals; Animals, Newborn; Axons; Calcium; Electric Stimulation; Fluorescent Dyes; Glutamates; Glutamic Acid; Kinetics; Microscopy, Fluorescence; Models, Neurological; Neuroglia; Neurons; Optic Nerve; Signal Transduction; Tetrodotoxin; Xanthenes	1993
Metabolite flux across portal-drained viscera, liver, and hindquarters of hyperinsulinemic, euglycemic beef steers. Journal of animal science, 1994, Volume: 72, Issue:11 Topics: Aging; Alanine; Animals; Biological Transport; Body Weight; Cattle; Glucose; Glucose Clamp Technique; Glutamic Acid; Glutamine; Hyperinsulinism; Insulin; Liver; Male; Muscle, Skeletal; Portal Vein; Random Allocation; Viscera	1994
Glucose deprivation increases aspartic acid release from synaptosomes of aged mice. Brain research, 1995, Feb-27, Volume: 673, Issue:1 Topics: Age Factors; Aging; Animals; Aspartic Acid; Brain; Energy Metabolism; Female; Glucose; Glutamic Acid; Mice; Synaptosomes	1995
Effect of acute stress on hippocampal glutamate levels and spectrin proteolysis in young and aged rats. Journal of neurochemistry, 1995, Volume: 65, Issue:1 Topics: Aging; Animals; Extracellular Space; Glutamic Acid; Hippocampus; Male; Peptide Hydrolases; Prefrontal Cortex; Rats; Rats, Inbred F344; Spectrin; Stress, Physiological	1995
Endogenous glutamate involvement in pulsatile secretion of gonadotropin-releasing hormone: evidence from effect of glutamine and developmental changes. Endocrinology, 1995, Volume: 136, Issue:3 Topics: Aging; Animals; Diazooxonorleucine; Glutamates; Glutamic Acid; Glutamine; Gonadotropin-Releasing Hormone; Male; Pulsatile Flow; Rats; Rats, Wistar; Veratridine	1995
K(+)- and transmitter-induced rises in [Ca2+]i in auditory neurones of developing rats. Neuroreport, 1994, Nov-21, Volume: 5, Issue:17 Topics: Aging; Animals; Animals, Newborn; Auditory Pathways; Calcium; Fura-2; Glutamic Acid; Glycine; Intracellular Membranes; Neurons; Neurotransmitter Agents; Olivary Nucleus; Osmolar Concentration; Potassium; Rats	1994
Carbachol-induced accumulation of inositol phosphates and its modulation by excitatory amino acids in cortical slices of young and aged rats with down-regulation of muscarinic M-1 receptors. Neurochemical research, 1994, Volume: 19, Issue:10 Topics: Aging; Analysis of Variance; Animals; Carbachol; Cerebral Cortex; Down-Regulation; Excitatory Amino Acids; Glutamic Acid; In Vitro Techniques; Inositol Phosphates; Isoflurophate; Male; N-Methylaspartate; Rats; Rats, Inbred F344; Receptors, Muscarinic; Syndrome	1994
Effect of repeated hyperammonemia on Na(+)-dependent binding of glutamate in rat cortical and hippocampal synaptic membranes. Neuroscience letters, 1993, Aug-06, Volume: 158, Issue:1 Topics: Aging; Ammonia; Animals; Brain Chemistry; Cerebral Cortex; Glutamates; Glutamic Acid; Hippocampus; Kinetics; Rats; Receptors, Glutamate; Sodium; Synaptic Membranes	1993
Mechanisms underlying developmental changes in the expression of metabotropic glutamate receptors in cultured cerebellar granule cells: homologous desensitization and interactive effects involving N-methyl-D-aspartate receptors. Molecular pharmacology, 1993, Volume: 44, Issue:5 Topics: Aging; Animals; Carbachol; Cells, Cultured; Cerebellum; Glutamates; Glutamic Acid; Hydrolysis; N-Methylaspartate; Phosphatidylinositol Phosphates; Potassium; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; RNA, Messenger	1993
Differential responses in cyclic GMP formation induced by excitatory amino acids (EAA) and sodium nitroprusside (SNP) in various regions of the brain and of rats of varied age. The International journal of biochemistry, 1993, Volume: 25, Issue:11 Topics: Aging; Amino Acids; Animals; Brain; Cyclic GMP; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Nitroprusside; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sex Characteristics	1993
Unchanged exocytotic release of glutamic acid in cortex and neostriatum of the rat during aging. Brain research bulletin, 1994, Volume: 33, Issue:3 Topics: 4-Aminopyridine; Aging; Animals; Basal Ganglia; Cerebral Cortex; Corpus Striatum; Exocytosis; Glutamates; Glutamic Acid; Male; Nerve Endings; Rats; Rats, Wistar; Synaptosomes	1994
Protection by dihydroergocryptine of glutamate-induced neurotoxicity. Pharmacology & toxicology, 1993, Volume: 73, Issue:4 Topics: Aging; Animals; Cell Survival; Cells, Cultured; Cerebellar Cortex; Dihydroergotoxine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluoresceins; Glutamates; Glutamic Acid; Nerve Degeneration; Neurons; Peroxides; Propidium; Rats	1993
In vivo assessment of insulin binding in different organs of growing and adult glutamate-induced obese rats. Experimental and clinical endocrinology, 1993, Volume: 101, Issue:4 Topics: Aging; Animals; Blood Glucose; Blood Volume; Fatty Acids, Nonesterified; Glutamates; Glutamic Acid; Insulin; Iodine Radioisotopes; Male; Neurotransmitter Agents; Obesity; Organ Specificity; Radioligand Assay; Rats; Rats, Wistar	1993
Interactions of gamma-L-glutamyltaurine with excitatory aminoacidergic neurotransmission. Neurochemical research, 1994, Volume: 19, Issue:3 Topics: Aging; Animals; Aspartic Acid; Brain; Calcium; Cells, Cultured; Cerebellum; Cerebral Cortex; Cyclic GMP; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Kainic Acid; Mice; Neurons; Potassium; Rats; Rats, Wistar; Receptors, Glutamate; Stereoisomerism; Synaptic Transmission; Synaptosomes; Taurine	1994
Release of 3H-noradrenaline by excitatory amino acids from rat mediobasal hypothalamus and the influence of aging. Brain research bulletin, 1994, Volume: 33, Issue:6 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Amino Acids; Animals; Glutamates; Glutamic Acid; Hypothalamus, Middle; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Rats; Tritium	1994
High affinity [3H]glutamate uptake systems in normal and audiogenic seizure-susceptible mice. Brain research. Developmental brain research, 1994, Mar-18, Volume: 78, Issue:1 Topics: Acoustic Stimulation; Aging; Animals; Brain; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Kinetics; Male; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Nerve Tissue Proteins; Seizures; Synaptosomes	1994
High affinity uptake of glutamate and aspartate in the developing rat retina. Current eye research, 1994, Volume: 13, Issue:4 Topics: Aging; Animals; Aspartic Acid; Glutamates; Glutamic Acid; Kinetics; Rats; Retina; Subcellular Fractions; Synaptosomes	1994
Enhanced aspartate release related to epilepsy in (EL) mice. Journal of neurochemistry, 1994, Volume: 63, Issue:2 Topics: Aging; Animals; Aspartic Acid; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Potassium; Seizures; Species Specificity	1994
NMDA receptor function is enhanced in the hippocampus of aged rats. Neurochemical research, 1994, Volume: 19, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Cerebral Cortex; Corpus Striatum; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Hippocampus; Kinetics; Male; Organ Specificity; Rats; Rats, Inbred WKY; Receptors, N-Methyl-D-Aspartate; Tritium	1994
A possible role of glutamate in the aging process. Medical hypotheses, 1994, Volume: 42, Issue:4 Topics: Aging; Animals; Brain; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Headache; Humans; Rats; Vitamin E	1994
Membrane arachidonic acid concentration correlates with age and induction of long-term potentiation in the dentate gyrus in the rat. The European journal of neuroscience, 1994, Jun-01, Volume: 6, Issue:6 Topics: Aging; Animals; Arachidonic Acid; Electric Stimulation; Electrophysiology; Female; Glutamic Acid; Hippocampus; Long-Term Potentiation; Membrane Lipids; Membranes; Phospholipases; Rats; Synapses	1994
Excitatory amino acid receptors in membranes from cultured human retinal pigment epithelium. Current eye research, 1994, Volume: 13, Issue:8 Topics: Adolescent; Adult; Aging; Binding, Competitive; Cell Membrane; Cells, Cultured; Child; Child, Preschool; Excitatory Amino Acids; Glutamic Acid; Humans; Infant; Infant, Newborn; Pigment Epithelium of Eye; Receptors, Amino Acid; Receptors, Glutamate	1994
Plasticity of astroglial glutamate and gamma-aminobutyric acid uptake in cell cultures derived from postnatal mouse cerebellum. Journal of neurochemistry, 1993, Volume: 60, Issue:1 Topics: Aging; Animals; Animals, Newborn; Astrocytes; Autoradiography; Binding Sites; Cells, Cultured; Cerebellum; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Mice; Neuronal Plasticity; Neurons; Receptors, Adrenergic, beta	1993
Major differences in Ca2+i response to anoxia between neonatal and adult rat CA1 neurons: role of Ca2+o and Na+o. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1993, Volume: 13, Issue:1 Topics: Aging; Animals; Animals, Newborn; Calcium; Cytosol; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Hippocampus; Hypoxia; Neurons; Rats; Rats, Sprague-Dawley; Sodium	1993
Effects of a cold environment or age on methamphetamine-induced dopamine release in the caudate putamen of female rats. Pharmacology, biochemistry, and behavior, 1993, Volume: 44, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Caudate Nucleus; Chromatography, High Pressure Liquid; Cold Temperature; Dialysis; Dopamine; Female; Glutamates; Glutamic Acid; Hippocampus; Methamphetamine; Putamen; Rats; Rats, Sprague-Dawley; Serotonin; Taurine	1993
Changes in synaptosomal glutamate release during postnatal development in the rat hippocampus and cortex. Brain research. Developmental brain research, 1993, Jan-15, Volume: 71, Issue:1 Topics: Aging; Animals; Animals, Newborn; Biological Transport; Cerebral Cortex; Glutamates; Glutamic Acid; Hippocampus; Membrane Potentials; Potassium; Rats; Rats, Wistar; Serotonin; Sodium; Synaptosomes	1993
Glutamate and theta-rhythm stimulation selectively enhance NMDA component of EPSC in CA1 neurons of young rats. Neuroscience letters, 1993, Mar-05, Volume: 151, Issue:1 Topics: Aging; Animals; Arginine; Evoked Potentials; Glutamates; Glutamic Acid; Hemoglobins; In Vitro Techniques; N-Methylaspartate; Neuronal Plasticity; Neurons; Nitroarginine; Norepinephrine; Rats; Rats, Wistar; Synapses; Synaptic Transmission; Theta Rhythm	1993
Effects of excitatory amino acids on inositol phosphate accumulation in slices of the cerebral cortex of young and aged rats. Neurochemical research, 1993, Volume: 18, Issue:5 Topics: Aging; Amino Acids; Animals; Carbachol; Cerebral Cortex; Glutamates; Glutamic Acid; Inositol Phosphates; Male; N-Methylaspartate; Norepinephrine; Quisqualic Acid; Rats; Rats, Sprague-Dawley	1993
Extracellular glutamate levels increase with age in the lateral striatum: potential involvement of presynaptic D-2 receptors. Synapse (New York, N.Y.), 1993, Volume: 13, Issue:4 Topics: Aging; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis; Dopamine Agents; Electrochemistry; Extracellular Space; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Quinolines; Rats; Rats, Inbred F344; Receptors, Dopamine D2; Sulpiride; Synapses	1993
Postnatal changes in N-methyl-D-aspartate receptor binding and stimulation by glutamate and glycine of [3H]-MK-801 binding in human temporal cortex. British journal of pharmacology, 1993, Volume: 108, Issue:4 Topics: Adult; Aging; Cerebral Cortex; Dizocilpine Maleate; Female; Glutamates; Glutamic Acid; Glycine; Humans; In Vitro Techniques; Infant; Infant, Newborn; Male; Phencyclidine; Proteins; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical; Sudden Infant Death; Temporal Lobe	1993
Synaptic neurochemistry of human striatum during development: changes in sudden infant death syndrome. Journal of neurochemistry, 1993, Volume: 60, Issue:6 Topics: Acetylcholinesterase; Aging; Biogenic Amines; Biomarkers; Carnitine O-Acetyltransferase; Choline O-Acetyltransferase; Corpus Striatum; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Infant; Isoenzymes; Male; Monoamine Oxidase; Neurotransmitter Agents; Reference Values; Somatostatin; Sudden Infant Death; Synapses	1993
Phorbol ester- and glutamate-sensitive phosphorylation of hippocampal membrane proteins from adult and neonatal rats. Brain research. Developmental brain research, 1993, May-21, Volume: 73, Issue:1 Topics: Aging; Animals; Animals, Newborn; Glutamates; Glutamic Acid; Hippocampus; Male; Membrane Proteins; Phosphorylation; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Tissue Distribution	1993
Age-related effects of NMDA-stimulated concomitant release of nitric oxide and glutamate in cortical slices prepared from DBA/2 mice. Brain research, 1993, Jun-04, Volume: 613, Issue:1 Topics: Acoustic Stimulation; Aging; Animals; Cerebral Cortex; Disease Susceptibility; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Nitric Oxide; Seizures	1993
Age-dependent changes in some aspects of glutamate metabolism in the brain of the teleost, Channa punctatus. I. Ammonia and glutamine contents and glutamate dehydrogenase activity. Mechanisms of ageing and development, 1993, Volume: 68, Issue:1-3 Topics: Aging; Ammonia; Animals; Brain; Fishes; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Glutamine; Male	1993
Developmental changes in intracellular calcium regulation in rat cerebral cortex during hypoxia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1993, Volume: 13, Issue:5 Topics: Adenosine Triphosphate; Aging; Animals; Calcium; Cerebral Cortex; Cyanides; Glutamates; Glutamic Acid; Hypoxia; In Vitro Techniques; Intracellular Membranes; Iodoacetates; Iodoacetic Acid; Osmolar Concentration; Rats; Rats, Sprague-Dawley	1993
Glutamate activates phospholipase D in hippocampal slices of newborn and adult rats. Journal of neurochemistry, 1993, Volume: 61, Issue:4 Topics: Aging; Animals; Animals, Newborn; Cycloleucine; Enzyme Activation; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Phospholipase D; Rats	1993
Hippocampal changes in developing postnatal mice following intrauterine exposure to domoic acid. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1993, Volume: 13, Issue:10 Topics: Aging; Analysis of Variance; Animals; Brain; Calcium; Cerebral Cortex; Dose-Response Relationship, Drug; Electroencephalography; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Hippocampus; Kainic Acid; Kinetics; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Neurons; Neurotoxins; Pregnancy; Pyramidal Tracts; Receptors, Kainic Acid; Seizures	1993
L-glutamate and L-aspartate concentrations in the developing and aging human putamen tissue. Journal of neural transmission. General section, 1993, Volume: 93, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Aspartic Acid; Child; Child, Preschool; Female; Glutamates; Glutamic Acid; Humans; Infant; Male; Middle Aged; Putamen	1993
Effects of quisqualic acid and glutamate on subsequent learning, emotionality, and seizure susceptibility in the immature and mature animal. Brain research, 1993, Oct-01, Volume: 623, Issue:2 Topics: Administration, Inhalation; Aging; Animals; Disease Susceptibility; Emotions; Flurothyl; Glutamates; Glutamic Acid; Handling, Psychological; Learning; Male; Memory; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Seizures	1993
An ex vivo rat retinal preparation for excitotoxicity studies. Journal of neuroscience methods, 1995, Volume: 60, Issue:1-2 Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chick Embryo; Excitatory Amino Acid Agonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Rats; Rats, Sprague-Dawley; Retina	1995
Dopamine--glutamate--GABA interactions and ageing: studies in the striatum of the conscious rat. The European journal of neuroscience, 1995, Nov-01, Volume: 7, Issue:11 Topics: Aging; Animals; Apomorphine; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Male; Rats; Rats, Wistar; Time Factors	1995
Age-related changes in the uptake and release of glutamate and aspartate in the mouse brain. Mechanisms of ageing and development, 1995, Jul-14, Volume: 81, Issue:2-3 Topics: Aging; Animals; Aspartic Acid; Brain; Female; Glutamic Acid; Male; Mice; Mice, Inbred Strains; Rats	1995
In vivo proton magnetic resonance spectroscopy of the normal aging human brain. Life sciences, 1996, Volume: 58, Issue:22 Topics: Adult; Aged; Aging; Body Water; Brain; Choline; Creatine; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Middle Aged; Protons	1996
Decreased gonadotropin-releasing hormone neurosecretory response to glutamate agonists in middle-aged female rats on proestrus afternoon: a possible role in reproductive aging? Endocrinology, 1996, Volume: 137, Issue:6 Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arcuate Nucleus of Hypothalamus; Base Sequence; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Gonadotropin-Releasing Hormone; Kainic Acid; Luteinizing Hormone; Median Eminence; Molecular Sequence Data; N-Methylaspartate; Preoptic Area; Proestrus; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger	1996
Interaction between anionic amino acids and the mammary tissue (Na(+)-glutamate) cotransporter. Biochemical Society transactions, 1996, Volume: 24, Issue:2 Topics: Aging; Amino Acid Transport System X-AG; Amino Acids, Dicarboxylic; Animals; Aspartic Acid; Carrier Proteins; Female; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Mammary Glands, Animal; Organ Culture Techniques; Rats; Rats, Wistar; Sucrose; Symporters	1996
The modulatory effect of melatonin on the dopamine-glutamate interaction in the anterior hypothalamus during ageing. Neuroreport, 1995, Nov-27, Volume: 6, Issue:17 Topics: Aging; Amphetamine; Animals; Aspartic Acid; Chromatography, High Pressure Liquid; Dopamine; Dopamine Agents; Extracellular Space; Glutamic Acid; Hypothalamus, Anterior; Male; Melatonin; Rats; Rats, Wistar	1995
Aging reduces neostriatal responsiveness to N-methyl-D-aspartate and dopamine: an in vitro electrophysiological study. Neuroscience, 1996, Volume: 73, Issue:3 Topics: Age Factors; Aging; Animals; Cats; Dopamine; Dose-Response Relationship, Drug; Evoked Potentials; Glutamic Acid; In Vitro Techniques; Male; N-Methylaspartate; Neostriatum; Rats; Rats, Inbred F344	1996
Accumulation of DNA damage in aging neurons occurs through a mechanism other than apoptosis. Journal of neurochemistry, 1996, Volume: 67, Issue:4 Topics: Aging; Animals; Animals, Newborn; Apoptosis; Carcinogens; Cell Survival; Cerebral Cortex; DNA Damage; DNA Nucleotidylexotransferase; Female; Glutamic Acid; Male; Methylnitronitrosoguanidine; Microscopy, Fluorescence; Neurons; Protein Biosynthesis; Rats; Rats, Wistar	1996
Structure of the C-terminal tail of alpha-tubulin: increase of heterogeneity from newborn to adult. Journal of neurochemistry, 1996, Volume: 67, Issue:5 Topics: Aging; Amino Acid Sequence; Animals; Animals, Newborn; Antibodies; Brain; Chromatography, Affinity; Chromatography, High Pressure Liquid; Glutamic Acid; Mammals; Mass Spectrometry; Mice; Peptide Fragments; Protein Processing, Post-Translational; Tubulin	1996
Glutamine metabolism is changed in lymphocytes from aged rats. Physiology & behavior, 1996, Volume: 60, Issue:3 Topics: Aging; Animals; Glutamic Acid; Lymph Nodes; Lymphocytes; Male; Rats; Spleen; Thymus Gland	1996
Ageing is associated with changes in glutamate release, protein tyrosine kinase and Ca2+/calmodulin-dependent protein kinase II in rat hippocampus. European journal of pharmacology, 1996, Aug-15, Volume: 309, Issue:3 Topics: Aging; Animals; Calcium; Glutamic Acid; Hippocampus; Male; Protein Kinases; Protein-Tyrosine Kinases; Rats; Rats, Wistar	1996
The synergism between ACPD and arachidonic acid on glutamate release in hippocampus is age-dependent. European journal of pharmacology, 1996, Aug-15, Volume: 309, Issue:3 Topics: Aging; Animals; Arachidonic Acid; Cycloleucine; Drug Synergism; Excitatory Amino Acid Agonists; Glutamic Acid; Heparin; Hippocampus; Male; Rats; Rats, Wistar	1996
Stimulation of glutamine synthetase activity by excitatory amino acids in astrocyte cultures derived from aged mouse cerebral hemispheres may be associated with non-N-methyl-D-aspartate receptor activation. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1996, Volume: 14, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Aging; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Cell Division; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamate-Ammonia Ligase; Glutamic Acid; Mice; N-Methylaspartate; Neurotoxins; Quinoxalines; Receptors, N-Methyl-D-Aspartate	1996
Free radical scavenging activity of the Japanese herbal medicine toki-shakuyaku-san (TJ-23) and its effect on superoxide dismutase activity, lipid peroxides, glutamate, and monoamine metabolites in aged rat brain. Neurochemical research, 1996, Volume: 21, Issue:8 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amino Acids; Animals; Bepridil; Biogenic Monoamines; Biphenyl Compounds; Brain; Dopamine; Drugs, Chinese Herbal; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Glutamic Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Hydroxyl Radical; Lipid Peroxides; Methoxyhydroxyphenylglycol; Mice; Neurotransmitter Agents; Norepinephrine; Organ Specificity; Picrates; Plants, Medicinal; Rats; Serotonin; Superoxide Dismutase; Superoxides; Thiobarbituric Acid Reactive Substances	1996
The GABAergic control of gonadotropin-releasing hormone secretion in male rats during sexual maturation involves effects on hypothalamic excitatory and inhibitory amino acid systems. Neuroendocrinology, 1996, Volume: 64, Issue:4 Topics: Aging; Amino Acids; Animals; Animals, Newborn; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropin-Releasing Hormone; Hypothalamus; Male; Rats; Rats, Sprague-Dawley; Sexual Maturation; Taurine	1996
Regional and developmental variations in metabolite concentration in the rat brain and eye: a study using 1H NMR spectroscopy and high performance liquid chromatography. Neurochemical research, 1996, Volume: 21, Issue:9 Topics: Aging; Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Stem; Cerebellum; Cerebral Cortex; Chromatography, High Pressure Liquid; Corpus Callosum; Dipeptides; Eye; gamma-Aminobutyric Acid; Glutamic Acid; Hydrogen; Magnetic Resonance Spectroscopy; Olfactory Bulb; Oligodendroglia; Optic Nerve; Organ Specificity; Rats; Stem Cells	1996
Urinary excretion of 5-L-oxoproline (pyroglutamic acid) is increased in normal adults consuming vegetarian or low protein diets. The Journal of nutrition, 1996, Volume: 126, Issue:11 Topics: Adult; Aging; Analysis of Variance; Body Height; Body Mass Index; Body Weight; Circadian Rhythm; Diet, Protein-Restricted; Diet, Vegetarian; Female; Glutamic Acid; Humans; Male; Middle Aged; Nitrogen; Pyrrolidonecarboxylic Acid; Time Factors	1996
Distributions of taurine, glutamate, and glutamate receptors during post-natal development and plasticity in the rat brain. Advances in experimental medicine and biology, 1996, Volume: 403 Topics: Aging; Animals; Brain; Cerebellum; Dentate Gyrus; Entorhinal Cortex; Female; Glutamic Acid; Immunohistochemistry; Male; Nerve Regeneration; Neuronal Plasticity; Neurons; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Taurine	1996
Age-dependent effects of glutamate toxicity in the hippocampus. Brain research. Developmental brain research, 1996, Dec-23, Volume: 97, Issue:2 Topics: Aging; Animals; Drug Evaluation, Preclinical; Glutamic Acid; Hippocampus; Male; Microinjections; Rats; Rats, Sprague-Dawley; Seizures	1996
Granule cell disinhibition in dentate gyrus of genetically seizure susceptible El mice. Brain research, 1997, Jan-16, Volume: 745, Issue:1-2 Topics: Aging; Animals; Anticonvulsants; Bicuculline; Chromatography, High Pressure Liquid; Dentate Gyrus; Electrophysiology; Flunitrazepam; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Phenobarbital; Seizures	1997
N-methyl-D-aspartate-mediated glutamate toxicity in the developing rabbit retina. Journal of neuroscience research, 1997, Feb-15, Volume: 47, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Animals, Newborn; Cell Death; Cyclic GMP; Dextromethorphan; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rabbits; Receptors, N-Methyl-D-Aspartate; Retina	1997
Hippocampal N-methyl-D-aspartate and kainate binding in response to entorhinal cortex aspiration or 192 IgG-saporin lesions of the basal forebrain. Neuroscience, 1997, Volume: 77, Issue:3 Topics: Acetylcholinesterase; Aging; Animals; Antibodies, Monoclonal; Cholinergic Agents; Entorhinal Cortex; Glutamic Acid; Hippocampus; Immunotoxins; Kainic Acid; Kinetics; Male; N-Glycosyl Hydrolases; N-Methylaspartate; Neurons; Prosencephalon; Pyramidal Tracts; Radioligand Assay; Rats; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Ribosome Inactivating Proteins, Type 1; Saporins; Tritium	1997
Identifying monoaminergic, GABAergic, and cholinergic characteristics in immortalized neuronal cell lines. Neurochemical research, 1997, Volume: 22, Issue:5 Topics: Acetylcholine; Aging; Animals; Animals, Newborn; Aspartic Acid; Brain; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Cerebellum; Culture Media, Serum-Free; Dopamine; gamma-Aminobutyric Acid; Genes, myc; Glutamic Acid; Hippocampus; Hybrid Cells; Mice; Neuroblastoma; Neurons; Neurotransmitter Agents; Norepinephrine; PC12 Cells; Rats; Rhombencephalon; Serotonin	1997
Specific [3H]glutamate binding in the cerebral cortex and hippocampus of rats during development: effect of homocysteine-induced seizures. Neurochemical research, 1997, Volume: 22, Issue:5 Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Binding Sites; Cerebral Cortex; Glutamic Acid; Hippocampus; Homocysteine; Kainic Acid; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Wistar; Reference Values; Seizures; Synaptic Membranes; Tritium	1997
Age dependent sensitivity of the rat retina to the excitotoxic action of N-methyl-D-aspartate. Neurobiology of disease, 1995, Volume: 2, Issue:3 Topics: Age Factors; Aging; Animals; Excitatory Amino Acid Agonists; Glutamic Acid; In Vitro Techniques; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Retina	1995
Changes in baroreceptor vagal reflex performance in the developing rat. Pflugers Archiv : European journal of physiology, 1997, Volume: 434, Issue:4 Topics: Aging; Animals; Animals, Newborn; Baroreflex; Blood Pressure; Chemoreceptor Cells; Female; Glutamic Acid; Heart Conduction System; Heart Rate; Male; Medulla Oblongata; Microinjections; Rats; Rats, Sprague-Dawley; Reflex; Solitary Nucleus; Sympathetic Nervous System; Vagus Nerve	1997
Seizure-induced glutamate release in mature and immature animals: an in vivo microdialysis study. Neuroreport, 1997, May-27, Volume: 8, Issue:8 Topics: Aging; Animals; Brain Chemistry; Electroencephalography; Excitatory Amino Acid Agonists; Extracellular Space; Glutamic Acid; Kainic Acid; Male; Microdialysis; Muscarinic Agonists; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures	1997
Is hypothalamic GABA involved in immune function in relation to dietary protein during aging? Neurochemical research, 1997, Volume: 22, Issue:9 Topics: Aging; Animals; Antibody Formation; Cell Survival; Dietary Proteins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Hypothalamus; Male; Rats; Spleen; T-Lymphocytes, Cytotoxic	1997
Glutamate affects the development of the thalamofugal visual projection of the chick. Neuroscience letters, 1997, Jul-11, Volume: 230, Issue:1 Topics: Aging; Animals; Axonal Transport; Chickens; Glutamic Acid; Learning; Prosencephalon; Thalamus; Visual Pathways	1997
Glutamate uptake impairment and neuronal damage in young and aged rats in vivo. Journal of neurochemistry, 1997, Volume: 69, Issue:3 Topics: Aging; Amino Acids; Animals; Aspartic Acid; Corpus Striatum; Dicarboxylic Acids; Glutamic Acid; Hippocampus; Kainic Acid; Kinetics; Male; Microdialysis; Nerve Degeneration; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Wistar	1997
Effect of a glutamine-enriched diet on small bowel allograft during immunosuppressive therapy. Nutrition (Burbank, Los Angeles County, Calif.), 1997, Volume: 13, Issue:9 Topics: Aging; Alanine; Alkaline Phosphatase; Ammonia; Animals; Body Weight; Bromodeoxyuridine; Cell Division; Diet; Epithelial Cells; Glutamic Acid; Glutamine; Immunosuppression Therapy; Immunosuppressive Agents; Intestinal Mucosa; Intestine, Small; Male; Microvilli; Random Allocation; Rats; Rats, Inbred BN; Rats, Inbred Lew; Tacrolimus; Time Factors; Transplantation, Homologous	1997
The ability of aged rats to sustain long-term potentiation is restored when the age-related decrease in membrane arachidonic acid concentration is reversed. Neuroscience, 1997, Volume: 81, Issue:1 Topics: Aging; Animals; Arachidonic Acid; Dentate Gyrus; Diet; Electrophysiology; gamma-Linolenic Acid; Glutamic Acid; Long-Term Potentiation; Male; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synaptic Membranes	1997
Ontogeny of non-NMDA glutamate receptors in rat barrel field cortex: I. Metabotropic receptors. The Journal of comparative neurology, 1997, Sep-15, Volume: 386, Issue:1 Topics: Aging; Animals; Animals, Newborn; Autoradiography; Cycloleucine; Gene Expression Regulation, Developmental; Glutamic Acid; Immunohistochemistry; Neuroprotective Agents; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Somatosensory Cortex; Tritium; Vibrissae	1997
Synaptic vesicle glutamate uptake in epileptic (EL) mice. Neurochemistry international, 1997, Volume: 31, Issue:4 Topics: Adenosine Triphosphate; Aging; Animals; Brain; Epilepsy; Glutamic Acid; Handling, Psychological; Mice; Mice, Inbred Strains; Reference Values; Synaptic Vesicles	1997
Status epilepticus-induced alterations in metabotropic glutamate receptor expression in young and adult rats. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Nov-01, Volume: 17, Issue:21 Topics: Aging; Animals; Animals, Suckling; Cell Death; Dentate Gyrus; Excitatory Amino Acid Agonists; Gene Expression Regulation, Developmental; Glutamic Acid; In Situ Hybridization, Fluorescence; Kainic Acid; Male; Mossy Fibers, Hippocampal; Nerve Degeneration; Nerve Tissue Proteins; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; RNA, Messenger; Status Epilepticus	1997
Presynaptic modulation of glutamate release targets different calcium channels in rat cerebrocortical nerve terminals. The European journal of neuroscience, 1997, Volume: 9, Issue:10 Topics: Adenosine; Aging; Aminobutyrates; Animals; Cadmium Chloride; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Egtazic Acid; Exocytosis; Glutamic Acid; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Phorbol Esters; Potassium Chloride; Protein Kinase C; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Purinergic P1; Spider Venoms; Synaptosomes	1997
Dopamine-glutamate interactions in the prefrontal cortex of the conscious rat: studies on ageing. Mechanisms of ageing and development, 1997, Dec-01, Volume: 99, Issue:1 Topics: Aging; Animals; Dopamine; Glutamic Acid; Male; Prefrontal Cortex; Rats; Rats, Wistar	1997
Aging is associated with a decrease in synaptosomal glutamate uptake and an increase in the susceptibility of synaptosomal vitamin E to oxidative stress. Neurochemical research, 1998, Volume: 23, Issue:2 Topics: Aging; Animals; Brain; Female; Glutamic Acid; Oxidative Stress; Rats; Rats, Inbred F344; Subcellular Fractions; Synaptosomes; Vitamin E	1998
Glutamatergic activation of hippocampal phospholipase D: postnatal fading and receptor desensitization. Journal of neurochemistry, 1998, Volume: 70, Issue:4 Topics: Aging; Animals; Animals, Newborn; Enzyme Activation; Glutamic Acid; Hippocampus; In Vitro Techniques; Phospholipase D; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate	1998
Hypothalamic GABA-ergic activity and T-cell proliferation in aged mammal: effect of dietary protein. Neurochemistry international, 1998, Volume: 32, Issue:2 Topics: 4-Aminobutyrate Transaminase; Aging; Animals; Diet, Protein-Restricted; Dietary Proteins; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamus; Lymphocyte Activation; Male; Rats; T-Lymphocytes	1998
Hypoxia-tolerant neonatal CA1 neurons: relationship of survival to evoked glutamate release and glutamate receptor-mediated calcium changes in hippocampal slices. Brain research. Developmental brain research, 1998, Mar-12, Volume: 106, Issue:1-2 Topics: Aging; Animals; Animals, Newborn; Calcium; Cell Hypoxia; Cell Survival; Cytosol; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley	1998
Release of endogenous glutamate, aspartate, GABA, and taurine from hippocampal slices from adult and developing mice under cell-damaging conditions. Neurochemical research, 1998, Volume: 23, Issue:4 Topics: Aging; Animals; Aspartic Acid; Brain Ischemia; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Hypoxia; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Potassium; Taurine	1998
A neuropharmacological analysis of PTZ-induced kindling in mice. General pharmacology, 1998, Volume: 31, Issue:1 Topics: Aging; Animals; Anticonvulsants; Convulsants; Diazepam; Glutamic Acid; Kindling, Neurologic; Male; Membranes; Mice; Pentylenetetrazole; Phenobarbital	1998
[Studies on changes in trace elements of the brain related to aging]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1998, Volume: 73, Issue:2 Topics: Aging; Animals; Brain; Glutamic Acid; Glycine; Humans; Learning Disabilities; Male; Memory Disorders; Mice; Mice, Inbred Strains; Neurotransmitter Agents; Rats; Trace Elements	1998
Analysis of the effect of membrane arachidonic acid concentration on modulation of glutamate release by interleukin-1: an age-related study. Experimental gerontology, 1998, Volume: 33, Issue:4 Topics: Aging; Animals; Arachidonic Acid; Diet; gamma-Linolenic Acid; Glutamic Acid; Hippocampus; Interleukin-1; Male; Membranes; Osmolar Concentration; Rats; Rats, Wistar	1998
The glutathione content of retinal Müller (glial) cells: the effects of aging and of application of free-radical scavengers. Ophthalmic research, 1998, Volume: 30, Issue:6 Topics: Aging; Animals; Cells, Cultured; Culture Media; Cystine; Flavonoids; Free Radical Scavengers; Ginkgo biloba; Glutamic Acid; Glutathione; Guinea Pigs; Male; Neuroglia; Plant Extracts; Retina	1998
Altered Ca2+ signaling and mitochondrial deficiencies in hippocampal neurons of trisomy 16 mice: a model of Down's syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Sep-15, Volume: 18, Issue:18 Topics: Aging; Alzheimer Disease; Animals; Calcium; Carcinogens; Cell Death; Cyclosporine; Diploidy; Disease Models, Animal; Down Syndrome; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Karyotyping; Male; Membrane Potentials; Mice; Mice, Neurologic Mutants; Mitochondria; NADP; Neurons; Potassium; Quinoxalines; Signal Transduction; Trisomy; Vitamin E	1998
Selective loss of phorbol-12,13-dibutyrate-facilitated L-glutamate transport in forebrain neurons of aged rats. The journals of gerontology. Series A, Biological sciences and medical sciences, 1998, Volume: 53, Issue:6 Topics: Aging; Animals; Biological Transport; Glutamic Acid; Hybridization, Genetic; Male; Neurons; Phorbol 12,13-Dibutyrate; Prosencephalon; Rats; Rats, Inbred BN; Rats, Inbred F344	1998
The potent mGlu receptor antagonist LY341495 identifies roles for both cloned and novel mGlu receptors in hippocampal synaptic plasticity. Neuropharmacology, 1998, Volume: 37, Issue:12 Topics: Aging; Amino Acids; Animals; Binding, Competitive; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Cycloleucine; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Humans; In Vitro Techniques; Long-Term Potentiation; Neuronal Plasticity; Rats; Receptors, Metabotropic Glutamate; Recombinant Proteins; Resorcinols; Transfection; Xanthenes	1998
Age-related changes in septal serotonergic, GABAergic and glutamatergic facilitation of retention in SAMP8 mice. Mechanisms of ageing and development, 1998, Sep-15, Volume: 105, Issue:1-2 Topics: Aging; Animals; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Glutamic Acid; Mice; Neurotransmitter Agents; Receptors, GABA-A; Receptors, GABA-B; Receptors, Serotonin; Serotonin Antagonists	1998
Linear summation of excitatory inputs by CA1 pyramidal neurons. Neuron, 1999, Volume: 22, Issue:2 Topics: Action Potentials; Afferent Pathways; Aging; Animals; Cell Membrane; Dendrites; Electric Conductivity; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Intracellular Membranes; Iontophoresis; Potassium; Pyramidal Cells; Rats; Rats, Sprague-Dawley	1999
Reverse transport of glutamate during depolarization in immature hippocampal slices. Brain research, 1999, Feb-20, Volume: 819, Issue:1-2 Topics: Aging; Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Biological Transport; Calcium; Dicarboxylic Acids; Extracellular Space; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Neurotransmitter Uptake Inhibitors; Potassium; Pyrrolidines; Rats; Rats, Wistar; Sodium	1999
[Interaction of neurotransmitters in specific circuits of the brain]. Anales de la Real Academia Nacional de Medicina, 1998, Volume: 115, Issue:3 Topics: Aging; Animals; Brain; Brain Diseases; Cerebral Cortex; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Neostriatum; Neurotransmitter Agents; Rats; Receptors, Dopamine; Receptors, GABA; Receptors, Glutamate; Synaptic Transmission	1998
Striatal A2A adenosine receptors differentially regulate spontaneous and K+-evoked glutamate release in vivo in young and aged rats. Neuroreport, 1999, Mar-17, Volume: 10, Issue:4 Topics: Adenosine; Aging; Animals; Aspartic Acid; Extracellular Space; Glutamic Acid; Male; Microdialysis; Neostriatum; Phenethylamines; Potassium; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1	1999
Age-dependent differences in glutamate-induced phosphorylation systems in rat hippocampal slices. Hippocampus, 1999, Volume: 9, Issue:2 Topics: Aging; Animals; Brain Chemistry; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin-Binding Proteins; Casein Kinase II; Cyclic AMP-Dependent Protein Kinases; Dynamins; Excitatory Amino Acid Agonists; Glutamic Acid; GTP Phosphohydrolases; Hippocampus; Intramolecular Oxidoreductases; Lipocalins; Male; Methoxyhydroxyphenylglycol; N-Methylaspartate; Nerve Tissue Proteins; Neurogranin; Organ Culture Techniques; Perchlorates; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Signal Transduction; Solubility; Subcellular Fractions; tau Proteins	1999
An age-related decline in striatal taurine is correlated with a loss of dopaminergic markers. Brain research bulletin, 1999, Volume: 48, Issue:3 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biomarkers; Brain-Derived Neurotrophic Factor; Corpus Striatum; Dopamine; Glutamic Acid; Glutamine; Hippocampus; Male; Maze Learning; Nerve Growth Factors; Rats; Rats, Long-Evans; Reaction Time; Space Perception; Taurine; Temporal Lobe	1999
Activation of p42 mitogen-activated protein kinase by arachidonic acid and trans-1-amino-cyclopentyl-1,3- dicarboxylate impacts on long-term potentiation in the dentate gyrus in the rat: analysis of age-related changes. Neuroscience, 1999, Volume: 90, Issue:4 Topics: Aging; Animals; Arachidonic Acid; Cycloleucine; Dentate Gyrus; Drug Synergism; Electric Stimulation; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Glutamic Acid; Long-Term Potentiation; Male; Mitogen-Activated Protein Kinase 1; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate	1999
Developmental sex differences in amino acid neurotransmitter levels in hypothalamic and limbic areas of rat brain. Neuroscience, 1999, Volume: 90, Issue:4 Topics: Aging; Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamus; Limbic System; Male; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Sex Characteristics; Testosterone	1999
Changing patterns of spatial buffering of glutamate in developing rat retinae are mediated by the Müller cell glutamate transporter GLAST. Cell and tissue research, 1999, Volume: 297, Issue:1 Topics: Aging; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Biological Transport; Glutamic Acid; Photoreceptor Cells, Vertebrate; Rats; Rats, Wistar; Retina	1999
Levels of amino acid neurotransmitters during mouse cerebellar neurogenesis and in histotypic cerebellar cultures. Developmental neuroscience, 1999, Volume: 21, Issue:2 Topics: Aging; Animals; Animals, Newborn; Aspartic Acid; Cells, Cultured; Cerebellum; Chromatography, High Pressure Liquid; Embryonic and Fetal Development; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Mice; Mice, Inbred Strains; Neurons; Neurotransmitter Agents; Taurine	1999
Increased glutathione levels in neurochemically identified fibre systems in the aged rat lumbar motor nuclei. The European journal of neuroscience, 1999, Volume: 11, Issue:8 Topics: Aging; Animals; Axons; gamma-Aminobutyric Acid; Glutamic Acid; Glutathione; Glycine; Immunohistochemistry; In Vitro Techniques; Lumbosacral Region; Male; Microscopy, Electron; Nerve Fibers; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Spinal Cord	1999
Repeated seizure-associated long-lasting changes of N-methyl-D-aspartate receptor properties in the developing rat brain. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1999, Volume: 17, Issue:4 Topics: Aging; Animals; Animals, Newborn; Binding Sites; Binding, Competitive; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Rats; Receptors, N-Methyl-D-Aspartate; Recurrence; Seizures; Time Factors	1999
Dopamine affects parvalbumin expression during cortical development in vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Oct-15, Volume: 19, Issue:20 Topics: Aging; Animals; Animals, Newborn; Cerebral Cortex; Dopamine; Glutamic Acid; In Vitro Techniques; Nerve Fibers; Neurons; Parvalbumins; Rats; Receptors, Dopamine D1; Receptors, Dopamine D2	1999
Effects of aging on the interaction between glutamate, dopamine, and GABA in striatum and nucleus accumbens of the awake rat. Journal of neurochemistry, 1999, Volume: 73, Issue:5 Topics: Aging; Animals; Corpus Striatum; Dicarboxylic Acids; Dopamine; Drug Interactions; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Nucleus Accumbens; Pyrrolidines; Rats; Rats, Wistar	1999
Aging selectively decreases oxidative capacity in rat heart interfibrillar mitochondria. Archives of biochemistry and biophysics, 1999, Dec-15, Volume: 372, Issue:2 Topics: Adenosine Diphosphate; Aging; Animals; Ascorbic Acid; Cell Respiration; Citrate (si)-Synthase; Electron Transport; Electron Transport Complex IV; Glutamic Acid; Male; Mitochondria, Heart; Myocardium; NADH Dehydrogenase; Oxidative Phosphorylation; Phosphatidylcholines; Phospholipids; Rats; Rats, Inbred F344; Sarcolemma; Succinate Cytochrome c Oxidoreductase; Uncoupling Agents	1999
The ontogeny of glutamate receptors and D-aspartate binding sites in the ovine CNS. Brain research. Developmental brain research, 1999, Dec-10, Volume: 118, Issue:1-2 Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Aspartic Acid; Autoradiography; Binding Sites; Brain; Embryonic and Fetal Development; Fetus; Glutamic Acid; Kainic Acid; N-Methylaspartate; Receptors, Glutamate; Sheep	1999
Age-related changes in synaptic function: analysis of the effect of dietary supplementation with omega-3 fatty acids. Neuroscience, 1999, Volume: 94, Issue:1 Topics: Aging; Animals; Arachidonic Acid; Cycloleucine; Dentate Gyrus; Docosahexaenoic Acids; Eating; Excitatory Postsynaptic Potentials; Fatty Acids, Omega-3; Glutamic Acid; Long-Term Potentiation; Male; Neurons; Neuroprotective Agents; Perforant Pathway; Potassium Chloride; Rats; Rats, Wistar; Synapses; Synaptic Transmission; Synaptosomes	1999
Developmental sex differences in calbindin-D(28K) and calretinin immunoreactivity in the neonatal rat hypothalamus. Journal of neurobiology, 2000, Feb-15, Volume: 42, Issue:3 Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Calbindin 2; Calbindins; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamus; Immunohistochemistry; Male; Nerve Tissue Proteins; Preoptic Area; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G; Sex Characteristics; Ventromedial Hypothalamic Nucleus	2000
In vitro proton and phosphorus NMR spectroscopic analysis of murine (C57Bl/6J) brain development. NMR in biomedicine, 1999, Volume: 12, Issue:7 Topics: Aging; Animals; Aspartic Acid; Brain; Brain Chemistry; Chloroform; Creatine; gamma-Aminobutyric Acid; Glutamic Acid; Magnetic Resonance Spectroscopy; Methanol; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Phosphatidylinositols; Phosphorus; Protons; Taurine	1999
Effect of aluminium-induced Alzheimer like condition on oxidative energy metabolism in rat liver, brain and heart mitochondria. Mechanisms of ageing and development, 1999, Dec-07, Volume: 112, Issue:1 Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Aging; Aluminum Chloride; Aluminum Compounds; Alzheimer Disease; Animals; Body Temperature; Brain; Chlorides; Disease Models, Animal; Energy Metabolism; Glutamic Acid; Male; Membrane Fluidity; Mitochondria, Heart; Mitochondria, Liver; Oxidative Phosphorylation; Rats	1999
Lack of effect of ageing on acetate oxidation in rat skeletal muscle during starvation: a (13)C NMR study. The Journal of experimental biology, 2000, Volume: 203, Issue:Pt 6 Topics: Acetates; Aging; Animals; Female; Glutamic Acid; Magnetic Resonance Spectroscopy; Muscle, Skeletal; Oxidation-Reduction; Rats; Rats, Wistar; Starvation	2000
Declines in mRNA expression of different subunits may account for differential effects of aging on agonist and antagonist binding to the NMDA receptor. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Mar-01, Volume: 20, Issue:5 Topics: Aging; Animals; Binding, Competitive; Brain Chemistry; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression; Glutamic Acid; In Situ Hybridization; Male; Mice; Mice, Inbred C57BL; Piperazines; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tritium	2000
Protective effect of the energy precursor creatine against toxicity of glutamate and beta-amyloid in rat hippocampal neurons. Journal of neurochemistry, 2000, Volume: 74, Issue:5 Topics: Aging; Amyloid beta-Peptides; Animals; Cells, Cultured; Creatine; Dendrites; Energy Metabolism; Glutamic Acid; Hippocampus; Intracellular Membranes; Neurons; Neuroprotective Agents; Phosphocreatine; Rats	2000
Age-related resistance to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid-induced hippocampal lesion. Hippocampus, 2000, Volume: 10, Issue:3 Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Biomarkers; Calbindins; Calcinosis; Choline O-Acetyltransferase; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Nerve Tissue Proteins; Neurons; Parvalbumins; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G	2000
Striatal A2A adenosine receptor antagonism differentially modifies striatal glutamate outflow in vivo in young and aged rats. Neuroreport, 2000, Aug-03, Volume: 11, Issue:11 Topics: Adenosine; Age Factors; Aging; Animals; Aspartic Acid; Glutamic Acid; Male; Neostriatum; Neurons; Neuroprotective Agents; Potassium; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Time Factors; Triazoles	2000
Changes in anesthetic sensitivity and glutamate receptors in the aging canine brain. The journals of gerontology. Series A, Biological sciences and medical sciences, 2000, Volume: 55, Issue:9 Topics: Aging; Analysis of Variance; Anesthetics, Inhalation; Animals; Brain; Cerebral Cortex; Dizocilpine Maleate; Dogs; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Isoflurane; Male; Neurotransmitter Agents; Radiopharmaceuticals; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tritium	2000
The plastic brain. Neurobiology of disease, 2000, Volume: 7, Issue:5 Topics: Aging; Animals; Behavior, Animal; Brain; Child Development; Child, Preschool; Glutamic Acid; Humans; Neuronal Plasticity; Neurons; Synaptic Transmission	2000
NOC/oFQ contributes to age-dependent impairment of NMDA-induced cerebrovasodilation after brain injury. American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:5 Topics: Aging; Animals; Animals, Newborn; Arterioles; Blood Pressure; Brain Injuries; Cerebrovascular Circulation; Disease Models, Animal; Excitatory Amino Acids; Female; Glutamic Acid; Male; N-Methylaspartate; Narcotic Antagonists; Nociceptin; Nociceptin Receptor; Opioid Peptides; Peptide Fragments; Pia Mater; Receptors, Opioid; Swine; Vasoconstriction; Vasodilation; Wounds, Nonpenetrating	2000
Hypothermia inhibits ischemia-induced efflux of amino acids and neuronal damage in the hippocampus of aged rats. Brain research, 2000, Nov-24, Volume: 884, Issue:1--2 Topics: Aging; Alanine; Amino Acids; Animals; Aspartic Acid; Brain Ischemia; Cerebrovascular Circulation; Excitatory Amino Acids; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Hypothermia, Induced; Nerve Degeneration; Neural Inhibition; Neurons; Rats; Rats, Inbred SHR; Taurine	2000
Regional changes in the hippocampal density of AMPA and NMDA receptors across the lifespan of the rat. Brain research, 2000, Dec-01, Volume: 885, Issue:1 Topics: Aging; Animals; Dissection; Glutamic Acid; Hippocampus; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tritium	2000
NBQX attenuates excitotoxic injury in developing white matter. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Dec-15, Volume: 20, Issue:24 Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypoxia-Ischemia, Brain; Injections, Intraperitoneal; Male; Microinjections; Nerve Fibers, Myelinated; Neuroprotective Agents; Oligodendroglia; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Glutamate	2000
Glutamate and catabolites of high-energy phosphates in the striatum and brainstem of young and aged rats subchronically exposed to manganese. Aging (Milan, Italy), 2000, Volume: 12, Issue:5 Topics: Aging; Animals; Brain Stem; Corpus Striatum; Energy Metabolism; Glutamic Acid; Hypoxanthine; Male; Manganese; Osmolar Concentration; Phosphates; Rats; Rats, Wistar; Time Factors; Uric Acid; Xanthine	2000
Vesicle release probability and pre-primed pool at glutamatergic synapses in area CA1 of the rat neonatal hippocampus. The Journal of physiology, 2001, Mar-01, Volume: 531, Issue:Pt 2 Topics: Action Potentials; Aging; Animals; Animals, Newborn; Electric Stimulation; Electrophysiology; Glutamic Acid; Hippocampus; In Vitro Techniques; Probability; Rats; Rats, Wistar; Synapses; Synaptic Vesicles	2001
Endogenous glutamate-taurine interaction in striatum and nucleus accumbens of the freely moving rat: studies during the normal process of aging. Mechanisms of ageing and development, 2001, Apr-15, Volume: 122, Issue:4 Topics: Aging; Animals; Corpus Striatum; Dicarboxylic Acids; Glutamic Acid; Locomotion; Male; Microdialysis; Neurotransmitter Uptake Inhibitors; Nucleus Accumbens; Pyrrolidines; Rats; Rats, Wistar; Taurine	2001
Antagonistic effects of melatonin on glutamate release and neurotoxicity in cerebral cortex. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:9 Topics: Aging; Animals; Cells, Cultured; Cerebral Cortex; Glutamic Acid; Melatonin; Mice; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Synaptosomes	1999
Glutamate-glutamine cycle and aging in striatum of the awake rat: effects of a glutamate transporter blocker. Neurochemical research, 2001, Volume: 26, Issue:1 Topics: Aging; Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Corpus Striatum; Dicarboxylic Acids; Glutamic Acid; Glutamine; Male; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Wistar	2001
EAAT1 and EAAT2 immunoreactivity in transgenic mice with a G93A mutant SOD1 gene. Neuroreport, 2001, May-25, Volume: 12, Issue:7 Topics: Aging; Amino Acid Transport System X-AG; Amyotrophic Lateral Sclerosis; Animals; ATP-Binding Cassette Transporters; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Glutamic Acid; Immunohistochemistry; Mice; Mice, Transgenic; Motor Neurons; Mutation; Nerve Degeneration; Posterior Horn Cells; Receptors, Neurotransmitter; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1	2001
Glutamate-induced cobalt uptake reveals non-NMDA receptors in developing rat taste buds. Neuroreport, 2001, Jun-13, Volume: 12, Issue:8 Topics: Aging; Animals; Animals, Newborn; Cobalt; Glutamic Acid; In Vitro Techniques; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Staining and Labeling; Taste Buds	2001
MAP2 phosphorylation and visual plasticity in Xenopus. Brain research, 2001, Jun-29, Volume: 905, Issue:1-2 Topics: Aging; Animals; Dendrites; Dose-Response Relationship, Drug; Drug Administration Schedule; Excitatory Amino Acid Agonists; Glutamic Acid; Immunoblotting; Microtubule-Associated Proteins; N-Methylaspartate; Neuronal Plasticity; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Valine; Vision, Binocular; Visual Pathways; Xenopus laevis	2001
Decline in motor functions in aging is related to the loss of NMDA receptors. Brain research, 2001, Jul-13, Volume: 907, Issue:1-2 Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ankle Joint; Biomarkers; Biomechanical Phenomena; Brain Mapping; Cell Count; Dizocilpine Maleate; Dopamine; Electromyography; Female; Glutamic Acid; Learning Disabilities; Maze Learning; Movement Disorders; Muscle, Skeletal; Nerve Tissue Proteins; Pliability; Psychomotor Performance; Raclopride; Rats; Rats, Wistar; Reaction Time; Receptors, AMPA; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Tyrosine 3-Monooxygenase	2001
Alternate cadmium exposure differentially affects amino acid metabolism within the hypothalamus, median eminence, striatum and prefrontal cortex of male rats. Neurochemistry international, 2001, Volume: 39, Issue:3 Topics: Aging; Amino Acids; Animals; Aspartic Acid; Cadmium; Corpus Striatum; Glutamic Acid; Glutamine; Hypothalamus; Male; Median Eminence; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reference Values	2001
Glutamate inhibition of NMDA-induced hydroxyl radical release: an ontogenic study in rat. Neuroreport, 2001, Jul-03, Volume: 12, Issue:9 Topics: Aging; Animals; Animals, Newborn; Brain; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hydroxyl Radical; Microdialysis; N-Methylaspartate; Neurons; Neurotoxins; Oxidative Stress; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Salicylates	2001
Developmental depression of glutamate neurotransmission by chronic low-level activation of NMDA receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Aug-15, Volume: 21, Issue:16 Topics: Aging; Animals; Animals, Newborn; Down-Regulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-A Receptor Antagonists; Glutamic Acid; In Vitro Techniques; Magnesium; N-Methylaspartate; Neural Inhibition; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, GABA-A; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses; Synaptic Transmission	2001
Prolonged suppression of brain nitric oxide synthase activity by 7-nitroindazole protects against cerebral hypoxic-ischemic injury in neonatal rat. Brain & development, 2001, Volume: 23, Issue:5 Topics: Aging; Animals; Animals, Newborn; Brain; Dose-Response Relationship, Drug; Female; Glutamic Acid; Hypoxia-Ischemia, Brain; Indazoles; Male; Neurons; Neuroprotective Agents; Neurotoxins; Nitric Oxide; Nitric Oxide Synthase; Rats	2001
Partial resistance to malonate-induced striatal cell death in transgenic mouse models of Huntington's disease is dependent on age and CAG repeat length. Journal of neurochemistry, 2001, Volume: 78, Issue:4 Topics: Aging; Amino Acid Chloromethyl Ketones; Animals; bcl-X Protein; Blood Glucose; Cell Death; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Immunoblotting; Immunohistochemistry; Male; Malonates; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Nuclear Proteins; Proteins; Proto-Oncogene Proteins c-bcl-2; Succinate Dehydrogenase; Synaptosomes; Trinucleotide Repeats; X-Linked Inhibitor of Apoptosis Protein	2001
Age-related changes in the N-methyl-D-aspartate receptor binding sites within the human basal ganglia. Experimental neurology, 2001, Volume: 171, Issue:2 Topics: Adult; Aged; Aging; Autoradiography; Basal Ganglia; Caudate Nucleus; Cause of Death; Cocaine; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Female; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Nucleus Accumbens; Putamen; Radioligand Assay; Receptors, N-Methyl-D-Aspartate	2001
Taurine-, aspartate- and glutamate-like immunoreactivity identifies chemically distinct subdivisions of Kenyon cells in the cockroach mushroom body. The Journal of comparative neurology, 2001, Oct-22, Volume: 439, Issue:3 Topics: Aging; Animals; Antibody Specificity; Aspartic Acid; Axons; Body Patterning; Brain; Cell Size; Excitatory Amino Acids; Fluorescent Antibody Technique; Glutamic Acid; Growth Cones; Larva; Microscopy, Confocal; Mushroom Bodies; Neurotransmitter Agents; Nymph; Periplaneta; Taurine	2001
Developmental changes in the localisation of the mGluR1alpha subtype of metabotropic glutamate receptors in Purkinje cells. Neuroscience, 2001, Volume: 105, Issue:2 Topics: Afferent Pathways; Aging; Animals; Animals, Newborn; Cell Compartmentation; Cell Differentiation; Cerebellar Cortex; Fetus; Glutamic Acid; Immunohistochemistry; Male; Microscopy, Electron; Olivary Nucleus; Presynaptic Terminals; Purkinje Cells; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synaptic Transmission	2001
Changes in BDNF-immunoreactive structures in the hippocampal formation of the aged macaque monkey. Brain research, 2001, Nov-09, Volume: 918, Issue:1-2 Topics: Aging; Animals; Brain-Derived Neurotrophic Factor; Dendrites; Dentate Gyrus; Down-Regulation; Entorhinal Cortex; Female; Gene Expression Regulation; Glutamic Acid; Hippocampus; Immunohistochemistry; Long-Term Potentiation; Macaca; Male; Pyramidal Cells; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission	2001
In vivo NO/cGMP signalling in the hippocampus. Neurochemical research, 2001, Volume: 26, Issue:8-9 Topics: Aging; Animals; Cyclic GMP; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Nitric Oxide; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Signal Transduction	2001
Dual effects of NMDA receptor activation on polysialylated neural cell adhesion molecule expression during brainstem postnatal development. The European journal of neuroscience, 2001, Volume: 14, Issue:8 Topics: Aging; Animals; Calmodulin; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Free Radical Scavengers; GABA-A Receptor Antagonists; Glutamic Acid; Immunohistochemistry; Neural Cell Adhesion Molecule L1; Neural Cell Adhesion Molecules; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Sialic Acids; Solitary Nucleus; Vagus Nerve; Visceral Afferents	2001
Insulin promotes functional induction of silent synapses in differentiating rat neocortical neurons. The European journal of neuroscience, 2001, Volume: 14, Issue:8 Topics: Action Potentials; Aging; Animals; Animals, Newborn; Cell Differentiation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fetus; GABA-A Receptor Antagonists; Glutamic Acid; Insulin; Neocortex; Neural Pathways; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Rats; Reaction Time; Receptors, AMPA; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Tetrodotoxin; Thalamus	2001
Maturation of synaptic transmission at end-bulb synapses of the cochlear nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Dec-01, Volume: 21, Issue:23 Topics: Action Potentials; Aging; Animals; Auditory Pathways; Calcium; Chick Embryo; Chickens; Cochlear Nerve; Cochlear Nucleus; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; GABA-B Receptor Agonists; Glutamic Acid; In Vitro Techniques; Neurons; Nootropic Agents; Patch-Clamp Techniques; Pyrrolidinones; Receptors, AMPA; Receptors, GABA-B; Sensory Thresholds; Synapses; Synaptic Transmission; Synaptic Vesicles	2001
Long-term depression in the basolateral amygdala of the mouse involves the activation of interneurons. Neuroscience, 2001, Volume: 107, Issue:1 Topics: Aging; Amygdala; Animals; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Chelating Agents; Egtazic Acid; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Interneurons; Mice; Neural Inhibition; Neuronal Plasticity; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synaptic Transmission	2001
Reduced number of functional glutamatergic synapses in hippocampal neurons overexpressing full-length TrkB receptors. Journal of neuroscience research, 2001, Nov-01, Volume: 66, Issue:3 Topics: Aging; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Cells, Cultured; Dendrites; Down-Regulation; Excitatory Postsynaptic Potentials; Fluorescent Dyes; Gene Expression Regulation, Developmental; Glutamic Acid; Hippocampus; Nerve Growth Factors; Neuronal Plasticity; Neurons; Presynaptic Terminals; Protein Structure, Tertiary; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Receptor, trkB; Receptors, AMPA; Recombinant Fusion Proteins; Synapses; Up-Regulation	2001
Regulation of brain-derived neurotrophic factor transcripts by neuronal activation in rat hypothalamic neurons. Journal of neuroscience research, 2001, Nov-01, Volume: 66, Issue:3 Topics: Aging; Animals; Brain-Derived Neurotrophic Factor; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Exons; Fetus; Gene Expression Regulation, Developmental; Glutamic Acid; Hypothalamus; Neurons; Oligonucleotide Probes; Promoter Regions, Genetic; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptor, trkB; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleases; RNA, Messenger; Time Factors; Transcription, Genetic	2001
Developmental regulation of glutamate receptor field size by nonvesicular glutamate release. Nature neuroscience, 2002, Volume: 5, Issue:2 Topics: Aging; Animals; Down-Regulation; Drosophila; Electrophysiology; Embryo, Nonmammalian; Glutamic Acid; Neuromuscular Junction; Presynaptic Terminals; Receptors, Glutamate; Synapses; Tissue Distribution	2002
Occurrence of glutamate receptor subunit 1-containing aggresome-like structures during normal development of rat spinal cord interneurons. The Journal of comparative neurology, 2002, Jan-01, Volume: 442, Issue:1 Topics: Aging; Animals; Animals, Newborn; Calcium-Binding Proteins; Cysteine Endopeptidases; Cytoplasm; Cytoskeletal Proteins; Glutamic Acid; HSP70 Heat-Shock Proteins; Immunohistochemistry; Inclusion Bodies; Interneurons; Microscopy, Electron; Multienzyme Complexes; Neurodegenerative Diseases; Organelles; Proteasome Endopeptidase Complex; Protein Folding; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Spinal Cord; Synaptic Transmission; Ubiquitin	2002
Astrocytic and microglia cells reactivity induced by neonatal administration of glutamate in cerebral cortex of the adult rats. Journal of neuroscience research, 2002, Jan-15, Volume: 67, Issue:2 Topics: Aging; Animals; Animals, Newborn; Astrocytes; Bromodeoxyuridine; Cell Division; Cerebral Cortex; Disease Models, Animal; Female; Fluorescent Antibody Technique; Glial Fibrillary Acidic Protein; Gliosis; Glutamic Acid; Lectins; Male; Microglia; Neurodegenerative Diseases; Neurotoxins; Rats; Rats, Wistar; Stem Cells; Synaptic Transmission; Vimentin	2002
GLT-1 glutamate transporter levels are unchanged in mice expressing G93A human mutant SOD1. Journal of the neurological sciences, 2002, Jan-15, Volume: 193, Issue:2 Topics: Aging; Amino Acid Transport System X-AG; Amyotrophic Lateral Sclerosis; Animals; Carrier Proteins; Central Nervous System; Dimerization; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Female; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Immunohistochemistry; Male; Mice; Mice, Transgenic; Molecular Weight; Motor Neurons; Muscle Weakness; Mutation; Phenotype; Superoxide Dismutase; Superoxide Dismutase-1; Symporters	2002
Expression of the nerve growth factor receptors TrkA and p75NTR in the visual cortex of the rat: development and regulation by the cholinergic input. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Feb-01, Volume: 22, Issue:3 Topics: Acetylcholine; Aging; Animals; Cholinergic Fibers; Excitatory Amino Acid Agonists; Glutamic Acid; Immunoblotting; Microinjections; Nerve Growth Factor; Neurotransmitter Agents; Potassium; Prosencephalon; Quisqualic Acid; Rats; Rats, Long-Evans; Receptor, Nerve Growth Factor; Receptor, trkA; Receptors, Nerve Growth Factor; Sensory Deprivation; Synaptosomes; Up-Regulation; Visual Cortex	2002
Is age-induced decline in immune response associated with hypothalamic glutamate receptor density and dietary protein? Nutritional neuroscience, 2001, Volume: 4, Issue:5 Topics: Aging; Animals; Carbon Radioisotopes; Cell Division; Corticosterone; Cytotoxicity, Immunologic; Dietary Proteins; Dogs; Glutamic Acid; Hypothalamus; Immunity; Male; Receptors, Glutamate; T-Lymphocytes	2001
Age-related changes in GluR2 and NMDAR1 glutamate receptor subunit protein immunoreactivity in corticocortically projecting neurons in macaque and patas monkeys. Brain research, 2002, Feb-22, Volume: 928, Issue:1-2 Topics: Aging; Animals; Cell Differentiation; Cerebral Cortex; Erythrocebus patas; Female; Glutamic Acid; Haplorhini; Immunohistochemistry; Macaca fascicularis; Macaca mulatta; Male; Neural Pathways; Neurofilament Proteins; Neurons; Pyramidal Cells; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate	2002
Ontogenic modifications in the effect of the GABAergic system on the hypothalamic excitatory amino acids: its relationship with GABAergic control of gonadotrophin secretion during sexual maturation in female rats. Brain research. Developmental brain research, 2002, Jan-31, Volume: 133, Issue:1 Topics: Aging; Aminooxyacetic Acid; Animals; Aspartic Acid; Excitatory Amino Acids; Female; Follicle Stimulating Hormone; GABA Agents; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropins; Hypothalamus; Luteinizing Hormone; Neurons; Rats; Sexual Maturation; Synaptic Transmission	2002
Nicotine exposure during a postnatal critical period alters NR2A and NR2B mRNA expression in rat auditory forebrain. Brain research. Developmental brain research, 2002, Jan-31, Volume: 133, Issue:1 Topics: Aging; Animals; Animals, Newborn; Auditory Cortex; Environmental Exposure; Female; Gene Expression Regulation, Developmental; Geniculate Bodies; Glutamic Acid; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Synaptic Transmission; Tobacco Use Disorder	2002
The amino terminus of the glial glutamate transporter GLT-1 interacts with the LIM protein Ajuba. Molecular and cellular neurosciences, 2002, Volume: 19, Issue:2 Topics: Aging; Animals; Brain; Cell Membrane; Cerebellum; Cloning, Molecular; COS Cells; Cytoskeleton; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Homeodomain Proteins; Immunohistochemistry; Ion Channels; LIM Domain Proteins; Molecular Sequence Data; Neuroglia; Neurons; Protein Structure, Tertiary; Rats; Retina; Sequence Homology, Amino Acid; Two-Hybrid System Techniques; Viscera	2002
NMDAR-2C and 2D subunits gene expression is induced in brain by neonatal exposure of monosodium L-glutamate to adult rats. Neuroscience letters, 2002, Mar-15, Volume: 321, Issue:1-2 Topics: Aging; Animals; Animals, Newborn; Brain; Cell Differentiation; Dendrites; Gene Expression Regulation; Glutamic Acid; Hippocampus; Male; Neostriatum; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sodium Glutamate; Synapses	2002
Sexually dimorphic effect of glutamate treatment on cell cycle arrestment of astrocytes from the preoptic area of neonatal rats. Developmental neuroscience, 2001, Volume: 23, Issue:6 Topics: Aging; Animals; Animals, Newborn; Astrocytes; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Down-Regulation; Female; G1 Phase; Glutamic Acid; Male; Preoptic Area; Rats; Rats, Long-Evans; S Phase; Sex Characteristics	2001
A link between maze learning and hippocampal expression of neuroleukin and its receptor gp78. Journal of neurochemistry, 2002, Volume: 80, Issue:2 Topics: Aging; Animals; Gene Expression; Glucose-6-Phosphate Isomerase; Glutamic Acid; Hippocampus; Male; Maze Learning; Membrane Potentials; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Inbred F344; Receptors, Autocrine Motility Factor; Receptors, Cytokine; Receptors, Somatotropin; Ubiquitin-Protein Ligases	2002
The speeding of EPSC kinetics during maturation of a central synapse. The European journal of neuroscience, 2002, Volume: 15, Issue:5 Topics: Aging; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Antihypertensive Agents; Benzothiadiazines; Cell Differentiation; Cells, Cultured; Cerebellum; Dicarboxylic Acids; Excitatory Postsynaptic Potentials; Glutamic Acid; Kinetics; Male; Nerve Fibers; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Wistar; Receptors, AMPA; Synapses; Synaptic Transmission; Synaptic Vesicles	2002
Differential expression of phospholipase D1 in the developing retina. The European journal of neuroscience, 2002, Volume: 15, Issue:6 Topics: Aging; Animals; Animals, Newborn; Cell Differentiation; Cell Lineage; Female; Fetus; Glutamate-Ammonia Ligase; Glutamic Acid; Immunohistochemistry; Microtubule-Associated Proteins; Neuroglia; Neurons; Phospholipase D; Pregnancy; Rats; Rats, Sprague-Dawley; Retina; Signal Transduction; Stem Cells	2002
Differential susceptibility to ageing of rat preganglionic neurones projecting to the major pelvic ganglion and of their afferent inputs. Autonomic neuroscience : basic & clinical, 2002, Feb-28, Volume: 96, Issue:1 Topics: Afferent Pathways; Aging; Animals; Dendrites; Disease Susceptibility; Efferent Pathways; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hypogastric Plexus; Immunohistochemistry; Male; Microscopy, Electron; Nerve Degeneration; Neural Pathways; Parasympathetic Nervous System; Presynaptic Terminals; Rats; Rats, Wistar; Serotonin; Spinal Cord; Sympathetic Nervous System; Thyrotropin-Releasing Hormone	2002
Age-dependent changes in 24-hour rhythms of thymic and circulating growth hormone and adrenocorticotropin in rats injected with Freund's adjuvant. Neuroimmunomodulation, 2001, Volume: 9, Issue:5 Topics: Adrenocorticotropic Hormone; Aging; Animals; Aspartic Acid; Behavior, Animal; Chronobiology Disorders; Circadian Rhythm; Freund's Adjuvant; gamma-Aminobutyric Acid; Glutamic Acid; Growth Hormone; Immunologic Surveillance; Inflammation; Male; Pituitary-Adrenal System; Rats; Rats, Wistar; Taurine; Thymus Gland	2001
Electrophysiological characterization of retinal Müller glial cells from mouse during postnatal development: comparison with rabbit cells. Glia, 2002, Volume: 38, Issue:3 Topics: Aging; Animals; Animals, Newborn; Barium; Cell Differentiation; Cell Membrane; Electric Stimulation; Excitatory Amino Acid Transporter 2; Female; Glutamic Acid; Ion Channels; Male; Membrane Potentials; Mice; N-Methylaspartate; Neuroglia; Potassium Channels; Rabbits; Receptors, N-Methyl-D-Aspartate; Retina; Sodium Channels	2002
Distribution of two splice variants of the glutamate transporter GLT-1 in the developing rat retina. The Journal of comparative neurology, 2002, Jun-10, Volume: 447, Issue:4 Topics: Aging; Alternative Splicing; Amacrine Cells; Animals; Animals, Newborn; Cell Differentiation; Excitatory Amino Acid Transporter 2; Fetus; Glutamic Acid; Immunohistochemistry; Neural Pathways; Presynaptic Terminals; Protein Isoforms; Protein Structure, Tertiary; Rats; Rats, Inbred Strains; Retina; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells; Synaptic Transmission	2002
Alterations of amino acids and monoamine metabolism in male Fmr1 knockout mice: a putative animal model of the human fragile X mental retardation syndrome. Neural plasticity, 2001, Volume: 8, Issue:4 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Brain Stem; Cerebellum; Cerebral Cortex; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Fragile X Mental Retardation Protein; Fragile X Syndrome; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; Intellectual Disability; Male; Mice; Mice, Knockout; Models, Animal; Nerve Tissue Proteins; RNA-Binding Proteins; Serotonin; Taurine; Thalamus	2001
Bidirectional alterations in cerebellar synaptic transmission of tottering and rolling Ca2+ channel mutant mice. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Jun-01, Volume: 22, Issue:11 Topics: Aging; Animals; Ataxia; Calcium Channel Blockers; Calcium Channels; Calcium Channels, P-Type; Calcium Channels, Q-Type; Cerebellum; Disease Models, Animal; Disease Progression; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Homozygote; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Patch-Clamp Techniques; Purkinje Cells; Receptors, Glutamate; Synaptic Transmission	2002
In vivo assessment of lipid peroxidation products associated with age-related neurodegenerative diseases. Experimental neurology, 2002, Volume: 175, Issue:2 Topics: Aging; Aldehydes; Animals; Cerebral Cortex; Corpus Striatum; Glutamic Acid; Glyoxal; Lipid Peroxidation; Microdialysis; Neurodegenerative Diseases; Rats; Rats, Sprague-Dawley	2002
Activity-dependent decrease in NMDA receptor responses during development of the visual cortex. Science (New York, N.Y.), 1992, Nov-06, Volume: 258, Issue:5084 Topics: Action Potentials; Aging; Animals; Electric Conductivity; Glutamates; Glutamic Acid; Ion Channel Gating; Ion Channels; Neuronal Plasticity; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin; Visual Cortex	1992
Region-specific age effects on AMPA sensitivity: electrophysiological evidence for loss of synaptic contacts in hippocampal field CA1. Hippocampus, 1992, Volume: 2, Issue:4 Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Models, Neurological; Nerve Fibers; Neurons; Pyramidal Tracts; Rats; Synapses	1992
Development of the glutamate system in rabbit retina. Neurochemical research, 1992, Volume: 17, Issue:1 Topics: Aging; Animals; Animals, Newborn; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Immunohistochemistry; Photoreceptor Cells; Rabbits; Retina; Retinal Ganglion Cells	1992
Mitochondrial enzymes related to glutamate and GABA metabolism in the hippocampus of young and aged rats: a quantitative histochemical study. Neurochemical research, 1992, Volume: 17, Issue:2 Topics: 4-Aminobutyrate Transaminase; Aging; Animals; Electron Transport Complex IV; gamma-Aminobutyric Acid; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Hippocampus; Histocytochemistry; Isocitrate Dehydrogenase; Male; Mitochondria; Rats; Rats, Inbred Strains	1992
[Changes in excitatory amino acids and N-methyl-D-aspartate receptors in the brain in aged mice]. Zhonghua yi xue za zhi, 1992, Volume: 72, Issue:1 Topics: Action Potentials; Aging; Amino Acids; Animals; Cerebral Cortex; Glutamates; Glutamic Acid; Male; Memory; Mice; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission	1992
Age-related changes in transmitter glutamate and NMDA receptor/channels in the brain of senescence-accelerated mouse. Neuroscience letters, 1992, Mar-30, Volume: 137, Issue:2 Topics: Aging; Amino Acids; Animals; Brain; Cerebral Cortex; Dizocilpine Maleate; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; Kinetics; Mice; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate	1992
Hippocampal neuronal responsiveness to NMDA agonists and antagonists in the adult rat neonatally treated with MK-801. Brain research, 1992, Feb-14, Volume: 572, Issue:1-2 Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Animals, Newborn; Dizocilpine Maleate; Female; Glutamates; Glutamic Acid; Hippocampus; Iontophoresis; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate	1992
Age-related alterations of NMDA-receptor properties in the mouse forebrain: partial restoration by chronic phosphatidylserine treatment. Brain research, 1992, Jul-03, Volume: 584, Issue:1-2 Topics: Aging; Animals; Dizocilpine Maleate; Female; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Kinetics; Mice; Phosphatidylserines; Prosencephalon; Radioligand Assay; Receptors, N-Methyl-D-Aspartate	1992
Analgesia from the periaqueductal gray in the developing rat: focal injections of morphine or glutamate and effects of intrathecal injection of methysergide or phentolamine. Brain research, 1992, Jul-03, Volume: 584, Issue:1-2 Topics: Aging; Analgesia; Animals; Animals, Newborn; Catheterization; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Hot Temperature; Injections; Injections, Spinal; Methysergide; Morphine; Naloxone; Periaqueductal Gray; Phentolamine; Physical Stimulation; Rats	1992
The ontogeny of the uptake systems for glutamate, GABA, and glycine in synaptic vesicles isolated from rat brain. Neurochemical research, 1992, Volume: 17, Issue:5 Topics: Adenosine Triphosphate; Aging; Animals; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Rats; Rats, Inbred Strains; Synaptic Vesicles	1992
Cortical AMPA receptors: age-dependent regulation by cellular depolarization and agonist stimulation. Brain research. Developmental brain research, 1992, Aug-21, Volume: 68, Issue:2 Topics: Aging; Animals; Cerebral Cortex; Glutamates; Glutamic Acid; Kainic Acid; Male; Membrane Potentials; Muscimol; N-Methylaspartate; Neuronal Plasticity; Quisqualic Acid; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, AMPA; Receptors, Neurotransmitter; Veratridine	1992
Age-dependent regulation of GABAA receptors in neocortex. Brain research. Molecular brain research, 1992, Volume: 14, Issue:3 Topics: Aging; Animals; Baclofen; Cats; Cerebral Cortex; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kinetics; Muscimol; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Veratridine	1992
Effect of gamma-glutamyl transpeptidase inhibitors on the transport of glutamate into neuronal and glial primary cultures. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1992, Volume: 10, Issue:3 Topics: Aging; Animals; Biological Transport; Borates; Brain; Cells, Cultured; Chickens; Diazooxonorleucine; gamma-Glutamyltransferase; Glutamates; Glutamic Acid; Kainic Acid; Neuroglia; Neurons; Serine	1992
Regional distribution of glutamate and aspartate in adult and old human brain. Brain research, 1992, Oct-30, Volume: 594, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Aging; Animals; Aspartic Acid; Brain; Glutamates; Glutamic Acid; Humans; Male; Middle Aged; Rats	1992
Effects of ethanol on Na(+)-dependent amino acid uptake: dependence on rat age and Na+, K(+)-ATPase activity. Brain research, 1992, Oct-09, Volume: 593, Issue:1 Topics: Aging; Alcohols; Animals; Biological Transport; Cerebral Cortex; Dose-Response Relationship, Drug; Ethanol; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Intracellular Membranes; Kinetics; Male; Rats; Sodium; Sodium-Potassium-Exchanging ATPase; Synaptosomes	1992
Ammonia regulation of phosphate-activated glutaminase displays regional variation and impairment in the brain of aged rats. Neurochemical research, 1992, Volume: 17, Issue:11 Topics: Aging; Amino Acids; Ammonia; Animals; Brain; Chromatography, High Pressure Liquid; Glutamates; Glutamic Acid; Glutaminase; In Vitro Techniques; Male; Potassium; Rats; Rats, Inbred F344; Rats, Sprague-Dawley	1992
Kindling enhances sensitivity of CA3 hippocampal pyramidal cells to NMDA. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1992, Volume: 12, Issue:5 Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kindling, Neurologic; Magnesium; Male; N-Methylaspartate; Neurons; Rats; Rats, Inbred Strains	1992
Messenger RNAs coding for receptors and channels in the cerebral cortex of adult and aged rats. Brain research. Molecular brain research, 1992, Volume: 13, Issue:1-2 Topics: Acetylcholine; Aging; Animals; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; Male; Membrane Potentials; Oocytes; Poly A; Rats; Rats, Inbred F344; Receptors, Neurotransmitter; RNA, Messenger; Serotonin; Xenopus	1992
Developmental regulation of NMDA receptor-mediated synaptic currents at a central synapse. Nature, 1992, Jun-25, Volume: 357, Issue:6380 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Electric Stimulation; Evoked Potentials; Glutamates; Glutamic Acid; In Vitro Techniques; Ion Channels; Magnesium; Membrane Potentials; Neurons; Picrotoxin; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses; Time Factors	1992
Excitatory amino acid receptors coupled to the nitric oxide/cyclic GMP pathway in rat cerebellum during development. Journal of neurochemistry, 1991, Volume: 56, Issue:6 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Amino Acids; Animals; Cerebellum; Cyclic GMP; Female; Glutamates; Glutamic Acid; Male; Nitric Oxide; Quinoxalines; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Tetrodotoxin	1991
Effect of corticosterone treatment on energy metabolism in rat liver mitochondria. The Journal of steroid biochemistry and molecular biology, 1991, Volume: 38, Issue:5 Topics: Adenosine Diphosphate; Aging; Animals; Ascorbic Acid; Corticosterone; Energy Metabolism; Glutamates; Glutamic Acid; Liver; Male; Mitochondria, Liver; Organ Size; Oxidative Phosphorylation; Rats; Succinates; Succinic Acid; Tetramethylphenylenediamine	1991
[Transsynaptic and transmembrane control and aging--cellular and molecular aspect]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1991, Volume: 36, Issue:4 Topics: Acetylcholine; Aging; Animals; Dementia; Disease Models, Animal; Dopamine; Glutamates; Glutamic Acid; Mice; Norepinephrine; Signal Transduction; Synapses; Synaptic Transmission	1991
Accumulation and localization of two adult acinar cell secretory proteins during development of the rat submandibular gland. The American journal of anatomy, 1991, Volume: 191, Issue:2 Topics: Aging; Animals; Glutamates; Glutamic Acid; Glutamine; Glycoproteins; Microscopy, Electron; Mucins; Phenotype; Proteins; Rats; Submandibular Gland; Tissue Distribution	1991
The origin of free brain malonate. Neurochemical research, 1991, Volume: 16, Issue:2 Topics: Acetates; Acetic Acid; Acetyl Coenzyme A; Aging; Animals; Brain; Butyrates; Butyric Acid; Carbon Radioisotopes; Glutamates; Glutamic Acid; Kinetics; Malonates; Malonyl Coenzyme A; Rats	1991
Ischemia does not induce the release of excitotoxic amino acids from the hippocampus of newborn rats. Brain research. Developmental brain research, 1991, Jun-21, Volume: 60, Issue:2 Topics: Aging; Allopurinol; Animals; Animals, Newborn; Aspartic Acid; Brain Ischemia; Free Radicals; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Kinetics; Rats; Rats, Inbred Strains	1991
Induction of RSA-like oscillations in both the in-vitro and in-vivo hippocampus. Neuroreport, 1991, Volume: 2, Issue:7 Topics: Aging; Animals; Carbachol; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Picrotoxin; Procaine; Rats; Rats, Inbred Strains; Theta Rhythm	1991
Excitotoxic mechanisms, and age-related susceptibility to brain damage in ischemia, hypoglycemia and toxic mussel poisoning. Neurotoxicology, 1991,Fall, Volume: 12, Issue:3 Topics: Aging; Animals; Bivalvia; Brain Damage, Chronic; Brain Ischemia; Disease Susceptibility; Foodborne Diseases; Glutamates; Glutamic Acid; Hypoglycemia; Neurons	1991
The effect of age on binding of MK-801 in the cat visual cortex. Brain research. Developmental brain research, 1991, Sep-19, Volume: 62, Issue:1 Topics: Aging; Animals; Cats; Darkness; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Magnesium; Receptors, N-Methyl-D-Aspartate; Spermidine; Visual Cortex	1991
The ontogeny of the uptake systems for glycine, GABA and glutamate in synaptic vesicles isolated from rat spinal cord-medulla. Brain research. Developmental brain research, 1991, Dec-17, Volume: 64, Issue:1-2 Topics: Aging; Animals; Animals, Newborn; Cell Membrane; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Medulla Oblongata; Rats; Rats, Inbred Strains; Spinal Cord; Synaptic Vesicles	1991
Decreased glutamate release correlates with elevated dynorphin content in the hippocampus of aged rats with spatial learning deficits. Hippocampus, 1991, Volume: 1, Issue:4 Topics: Aging; Animals; Axons; Dynorphins; Glutamates; Glutamic Acid; Hippocampus; Learning Disabilities; Male; Microdialysis; Peptide Fragments; Radioimmunoassay; Rats; Rats, Inbred F344; Spatial Behavior; Synaptic Transmission	1991
Changes in messenger RNAs coding for neurotransmitter receptors and voltage-operated channels in the developing rat cerebral cortex. Developmental biology, 1990, Volume: 138, Issue:2 Topics: Aging; Animals; Cerebral Cortex; Electric Conductivity; Embryonic and Fetal Development; Female; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; Membrane Potentials; Membrane Proteins; Microinjections; Oocytes; Poly A; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; RNA, Messenger; Xenopus laevis	1990
Ion channel expression by white matter glia: the type-1 astrocyte. Neuron, 1990, Volume: 5, Issue:4 Topics: Aging; Animals; Astrocytes; Brain; Calcium; Cells, Cultured; Cytological Techniques; Denervation; Electrophysiology; Glutamates; Glutamic Acid; Immunohistochemistry; Ion Channel Gating; Ion Channels; Neuroglia; Neurons; Potassium	1990
Postnatal development of the excitatory amino acid system in visual cortex of the rat. Changes in uptake and levels of aspartate and glutamate. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1990, Volume: 8, Issue:2 Topics: Aging; Animals; Aspartic Acid; Glutamates; Glutamic Acid; Male; Rats; Rats, Inbred Strains; Visual Cortex	1990
The ontogeny of excitatory amino acid receptors in rat forebrain--I. N-methyl-D-aspartate and quisqualate receptors. Neuroscience, 1990, Volume: 35, Issue:1 Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Frontal Lobe; Glutamates; Glutamic Acid; Ibotenic Acid; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1990
Immunocytochemical and neurochemical evidence for age-related loss of GABA in the inferior colliculus: implications for neural presbycusis. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1990, Volume: 10, Issue:7 Topics: Acetylcholine; Aging; Animals; Aspartic Acid; Calcium; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hearing Loss, Sensorineural; Inferior Colliculi; Neurons; Potassium; Presbycusis; Rats; Rats, Inbred F344	1990
Neuroexcitatory plasma amino acids are elevated in migraine. Neurology, 1990, Volume: 40, Issue:10 Topics: Adult; Aging; Aspartic Acid; Female; Glutamates; Glutamic Acid; Headache; Humans; Male; Middle Aged; Migraine Disorders; Muscle Contraction; Osmolar Concentration; Time Factors	1990
Cloning of a novel glutamate receptor subunit, GluR5: expression in the nervous system during development. Neuron, 1990, Volume: 5, Issue:5 Topics: Aging; Animals; Base Sequence; Central Nervous System; Cloning, Molecular; Gene Expression Regulation; Genes; Glutamates; Glutamic Acid; In Vitro Techniques; Oocytes; Peripheral Nerves; Receptors, Glutamate; Receptors, Neurotransmitter; Xenopus	1990
Aging and stress-induced changes in choline and glutamate uptake in hippocampus and septum of two rat strains differing in longevity and reactivity to stressors. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1990, Volume: 8, Issue:6 Topics: Aging; Animals; Brain; Choline; Glutamates; Glutamic Acid; Hippocampus; Longevity; Male; Rats; Rats, Inbred Strains; Septum Pellucidum; Stress, Physiological	1990
Glutamate neurotoxicity in the cochlea: a possible consequence of ischaemic or anoxic conditions occurring in ageing. Acta oto-laryngologica. Supplementum, 1990, Volume: 476 Topics: Aging; Animals; Cell Hypoxia; Cochlea; Glutamates; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Humans; Ischemia; Kainic Acid; Neurotransmitter Agents; Presbycusis; Vestibulocochlear Nerve	1990
Ontogeny of glutamate accumulating activity in rat brain synaptic vesicles. Neuroscience letters, 1989, Feb-13, Volume: 97, Issue:1-2 Topics: Aging; Animals; Brain; Ca(2+) Mg(2+)-ATPase; Glutamates; Glutamic Acid; Membrane Proteins; Rats; Subcellular Fractions; Synaptic Vesicles	1989
Age-related alterations in noradrenergic input to the hippocampal formation: structural and functional studies in intraocular transplants. Brain research, 1989, Jan-30, Volume: 478, Issue:2 Topics: Action Potentials; Adrenergic Fibers; Aging; Animals; Female; Glutamates; Glutamic Acid; Hippocampus; Ocular Physiological Phenomena; Rats; Rats, Inbred Strains	1989
L-glutamate binding sites of normal and atrophic human cerebellum. Brain research, 1989, Feb-27, Volume: 481, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Binding, Competitive; Cerebellum; Child; Child, Preschool; Glutamates; Glutamic Acid; Humans; Infant; Infant, Newborn; Kinetics; Middle Aged; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter	1989
The development of N-methyl-D-aspartate receptors in cat visual cortex. Brain research. Developmental brain research, 1989, Apr-01, Volume: 46, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Binding, Competitive; Cats; Glutamates; Glutamic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Visual Cortex	1989
Postnatal changes in glutamate stimulated phosphoinositide turnover in rat neocortical synaptoneurosomes. Brain research. Developmental brain research, 1989, May-01, Volume: 47, Issue:1 Topics: Aging; Cerebral Cortex; Female; Glutamates; Glutamic Acid; Ibotenic Acid; Male; Phosphatidylinositols; Receptors, Amino Acid; Receptors, Cell Surface; Synaptosomes	1989
Transient increase of NMDA-binding sites in human hippocampus during development. Neuroscience letters, 1989, Apr-24, Volume: 99, Issue:1-2 Topics: Adult; Aging; Aspartic Acid; Fetus; Glutamates; Glutamic Acid; Hippocampus; Humans; Infant; Infant, Newborn; Middle Aged; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1989
Developmental changes in the chemosensitivity of rat brain synaptoneurosomes to excitatory amino acids, estimated by inositol phosphate formation. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1989, Volume: 7, Issue:3 Topics: Aging; Animals; Aspartic Acid; Carbachol; Female; Frontal Lobe; Glutamates; Glutamic Acid; Inositol Phosphates; Male; N-Methylaspartate; Norepinephrine; Oxadiazoles; Quisqualic Acid; Rats; Sugar Phosphates; Synaptosomes	1989
Changes in the amounts of amino acids associated with nerve endings (synaptosomes) during synaptogenesis. Neurochemical research, 1989, Volume: 14, Issue:4 Topics: Aging; Amino Acids; Animals; Brain; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; Olfactory Bulb; Rats; Rats, Inbred Strains; Synapses	1989
Strain-dependent decrease in glutamate binding to the N-methyl-D-aspartic acid receptor during aging. Neuroscience letters, 1989, Oct-09, Volume: 104, Issue:3 Topics: Aging; Animals; Glutamates; Glutamic Acid; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Species Specificity	1989
A biochemical correlate of the critical period for synaptic modification in the visual cortex. Science (New York, N.Y.), 1989, Nov-03, Volume: 246, Issue:4930 Topics: Aging; Animals; Aspartic Acid; Carbachol; Cattle; Glutamates; Glutamic Acid; Ibotenic Acid; N-Methylaspartate; Ocular Physiological Phenomena; Phosphatidylinositols; Synapses; Vision, Ocular; Visual Cortex	1989
Neurotoxicity at the N-methyl-D-aspartate receptor in energy-compromised neurons. An hypothesis for cell death in aging and disease. Annals of the New York Academy of Sciences, 1989, Volume: 568 Topics: Aging; Animals; Cell Survival; Cells, Cultured; Cerebellum; Energy Metabolism; Glucose; Glutamates; Glutamic Acid; Magnesium; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1989
Cellular uptake disguises action of L-glutamate on N-methyl-D-aspartate receptors. With an appendix: diffusion of transported amino acids into brain slices. British journal of pharmacology, 1985, Volume: 85, Issue:1 Topics: Aging; Animals; Aspartic Acid; Biological Transport; Brain; Cyclic GMP; Diffusion; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1985
Aspartate metabolism in rats during aging. Experimental gerontology, 1985, Volume: 20, Issue:3-4 Topics: Aging; Animals; Aspartic Acid; Brain; Carbon Dioxide; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Male; Rats; Rats, Inbred Strains	1985
Age-related changes of glucose metabolism in rat cerebral cortex with reference to glucose-derived amino acids. Neurochemical research, 1985, Volume: 10, Issue:12 Topics: Aging; Amino Acids; Animals; Carbon Dioxide; Cerebral Cortex; Glucose; Glutamates; Glutamic Acid; Male; Rats; Rats, Inbred Strains; Tissue Extracts	1985
Primary cultures from defined brain areas. III. Effects of seeding time on [3H]L-glutamate transport and glutamine synthetase activity. Brain research, 1986, Volume: 389, Issue:1-2 Topics: Aging; Animals; Animals, Newborn; Astrocytes; Biological Transport, Active; Brain; Brain Stem; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Embryo, Mammalian; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Kinetics; Rats; Time Factors	1986
Cerebral neocortical neurons in the aged rat: spontaneous activity, properties of pyramidal tract neurons and effect of acetylcholine and cholinergic drugs. Neuroscience, 1985, Volume: 16, Issue:4 Topics: Acetylcholine; Aging; Animals; Carbachol; Glutamates; Glutamic Acid; Male; Parasympathomimetics; Pyramidal Tracts; Rats; Rats, Inbred Strains; Reaction Time; Somatosensory Cortex	1985
Regional distribution of amino acid transmitters in postmortem brains of presenile and senile dementia of Alzheimer type. Annals of neurology, 1986, Volume: 19, Issue:3 Topics: Aged; Aging; Alzheimer Disease; Aspartic Acid; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Male; Middle Aged; Nerve Tissue Proteins; Osmolar Concentration; Postmortem Changes; Tissue Distribution	1986
[Aspartate aminotransferase activity high affinity (3H) glutamate/(3H) aspartate uptake in rat nervous tissue in postnatal development]. Acta histochemica. Supplementband, 1986, Volume: 33 Topics: Aging; Animals; Animals, Newborn; Aspartate Aminotransferases; Aspartic Acid; Autoradiography; Ganglia, Spinal; Ganglia, Sympathetic; Glutamates; Glutamic Acid; Hippocampus; Histocytochemistry; Rats; Tritium	1986
Glutamate-elicited stimulation of acetylcholinesterase activity in cerebellar slices from newborn rats. Neuroscience research, 1986, Volume: 3, Issue:5 Topics: Acetylcholinesterase; Aging; Animals; Animals, Newborn; Cerebellum; Cerebral Cortex; Cyclic GMP; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Rats; Rats, Inbred Strains	1986
A postmortem study of amino acid neurotransmitters in Alzheimer's disease. Annals of neurology, 1986, Volume: 20, Issue:5 Topics: Aged; Aging; Alanine; Alzheimer Disease; Amino Acids; Aspartic Acid; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Neurotransmitter Agents; Taurine	1986
[Changes in pharmacokinetics in aging and ways of correcting]. Vestnik Akademii meditsinskikh nauk SSSR, 1986, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biotransformation; Copper; Drug Combinations; Glutamates; Glutamic Acid; Humans; Kinetics; Male; Middle Aged; Potassium; Rabbits; Rats; Vitamins	1986
Ontogeny of adenosine 3',5'-monophosphate metabolism in guinea pig cerebral cortex. II. Development of responses to L-glutamate in the presence of adenosine or histamine. Molecular and cellular biochemistry, 1987, Volume: 73, Issue:2 Topics: Adenosine; Aging; Animals; beta-Alanine; Calcium; Cerebral Cortex; Cyclic AMP; Gestational Age; Glutamates; Glutamic Acid; Guinea Pigs; Histamine; Potassium Chloride	1987
Evidence for transient perinatal glutamatergic innervation of globus pallidus. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1987, Volume: 7, Issue:4 Topics: Adult; Aging; Animals; Autoradiography; Caudate Nucleus; Globus Pallidus; Glutamates; Glutamic Acid; Humans; Infant; Infant, Newborn; Putamen; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Muscarinic; Receptors, Neurotransmitter	1987
Septo-hippocampal neurons: altered properties in the aged rat. Brain research, 1987, Jul-28, Volume: 416, Issue:2 Topics: Action Potentials; Aging; Animals; Electric Stimulation; Glutamates; Glutamic Acid; Hippocampus; Male; Neural Pathways; Parasympathomimetics; Rats; Rats, Inbred Strains; Reaction Time; Septal Nuclei	1987
Utilization of plasma fatty acid in rat brain: distribution of [14C]palmitate between oxidative and synthetic pathways. Journal of neurochemistry, 1987, Volume: 49, Issue:5 Topics: Aging; Amino Acids; Animals; Brain; Gangliosides; Glutamates; Glutamic Acid; Glutamine; Kinetics; Lipid Metabolism; Male; Nerve Tissue Proteins; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Phospholipids; Rats; Rats, Inbred F344; Tissue Distribution	1987
Quisqualate-sensitive, chloride-dependent transport of glutamate into rat brain synaptosomes. Journal of neuroscience research, 1987, Volume: 18, Issue:3 Topics: Aging; Animals; Anions; Brain; Corpus Striatum; Glutamates; Glutamic Acid; Hippocampus; Kainic Acid; Male; Oxadiazoles; Potassium Chloride; Quisqualic Acid; Rats; Rats, Inbred Strains; Sodium Chloride; Synaptosomes	1987
Development of angiotensin II-sensitive OVLT neurons in SHR and WKY rats. Brain research, 1988, Mar-01, Volume: 467, Issue:1 Topics: Action Potentials; Aging; Angiotensin II; Animals; Glutamates; Glutamic Acid; Hypertension; Hypothalamus; In Vitro Techniques; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains	1988
Dopamine, acetylcholine, and glutamate interactions in aging. Behavioral and neurochemical correlates. Annals of the New York Academy of Sciences, 1988, Volume: 515 Topics: Acetylcholine; Aging; Animals; Behavior, Animal; Dopamine; Drug Interactions; Glutamates; Glutamic Acid; Humans; Hypoxia; Nervous System Diseases; Thiamine Deficiency	1988
Release of neurotransmitter amino acids from rat brain synaptosomes and its regulation in aging. Gerontology, 1988, Volume: 34, Issue:1-2 Topics: Aging; Amino Acids; Animals; Aspartic Acid; Brain; Calcium; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; Neurotransmitter Agents; Potassium; Rats; Synaptosomes	1988
Glutaminase in neurons and astrocytes cultured from mouse brain: kinetic properties and effects of phosphate, glutamate, and ammonia. Neurochemical research, 1988, Volume: 13, Issue:4 Topics: Aging; Ammonia; Animals; Animals, Newborn; Astrocytes; Brain; Cells, Cultured; Cerebellum; Cerebral Cortex; Fetus; Glutamates; Glutamic Acid; Glutaminase; Kinetics; Mice; Neurons; Phosphates	1988
Gamma-glutamyl transpeptidase, glutathione, and L-glutamic acid in the rat epididymis during postnatal development. Biology of reproduction, 1988, Volume: 38, Issue:5 Topics: Aging; Animals; Epididymis; gamma-Glutamyltransferase; Glutamates; Glutamic Acid; Glutathione; Hydrolysis; Male; Rats; Rats, Inbred Strains	1988
L-aspartate and L-glutamate binding sites in developing normal and 'nervous' mutant mouse cerebellum. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1987, Volume: 5, Issue:5-6 Topics: Aging; Amino Acids; Animals; Aspartic Acid; Binding, Competitive; Cerebellum; Female; Glutamates; Glutamic Acid; Kinetics; Male; Mice; Mice, Inbred C3H; Mice, Neurologic Mutants; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Glutamate; Receptors, Neurotransmitter	1987
Transient increased density of NMDA binding sites in the developing rat hippocampus. Brain research, 1988, Oct-04, Volume: 461, Issue:2 Topics: Aging; Animals; Aspartic Acid; Autoradiography; Binding, Competitive; Glutamates; Glutamic Acid; Hippocampus; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1988