glutamic acid and AIDS Dementia Complex

glutamic acid has been researched along with AIDS Dementia Complex in 50 studies

Research

Studies (50)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	13 (26.00)	18.2507
2000's	23 (46.00)	29.6817
2010's	12 (24.00)	24.3611
2020's	2 (4.00)	2.80

Authors

Authors	Studies
Al-Harthi, L; Gonzalez, H; Podany, A; Wallace, J	1
Chen, JM; Jiang, JJ; Liang, BY; Liao, YJ; Long, JY; Sapkota, K; Wei, JB; Zhou, Y; Zhou, YJ	1
Figuera-Losada, M; Potter, MC; Rojas, C; Slusher, BS	1
Algers, J; Brown, M; Buchthal, S; Campbell, T; Cohen, RA; Daar, E; Gongvatana, A; Harezlak, J; Heaton, R; McMahon, D; Mi, D; Navia, B; Robertson, K; Schifitto, G; Singer, E; So, YT; Taylor, M; Yiannoutsos, C; Zhong, J	1
Bressler, J; Kaufmann, W; O'Driscoll, CM; Rojas, CJ; Slusher, BS; Thomas, AG	1
Borgamann, K; Gelman, BB; Ghorpade, A; Joshi, C; Vartak-Sharma, N	1
Noel, RJ; Porter, JT; Rivera-Amill, V; Vázquez-Santiago, FJ	1
Anderson, C; Clifford, D; Cohen, B; Drewes, JL; Evans, S; Graham, D; Haughey, N; Hosey, L; McCarthy, S; Miyahara, S; Nath, A; Pardo, CA; Sacktor, N; Schifitto, G; Zink, MC	1
Blokhuis, C; Caan, MWA; Cohen, S; Kootstra, NA; Kuhle, J; Kuijpers, TW; Majoie, CBLM; Pajkrt, D; Reiss, P; Scherpbier, HJ; Ter Stege, JA; Teunissen, CE; Van Dalen, YW	1
Brecht, ML; Church, JA; Deville, J; Iqbal, Z; Keller, MA; Michalik, DE; Nielsen-Saines, K; Souza, R; Thomas, MA; Wilson, NE	1
Budka, H; Gelpi, E; Hayakawa, H; Izumo, S; Kubota, R; Xing, HQ	1
Curthoys, N; Erdmann, N; Herek, S; Huang, Y; Tian, C; Zhao, J; Zheng, J	1
Bazner, S; González, RG; Halpern, EF; Kim, WK; Lee, V; Lentz, MR; Rosenberg, ES; Venna, N; Williams, K	1
Buchthal, S; Chang, L; Ernst, T; Jiang, CS; Nakama, H	1
Curthoys, N; Huang, Y; Taylor, L; Tian, C; Vernon, H; Wang, Y; Zhao, L; Zheng, J	1
Cisneros, IE; Ghorpade, A	1
Al-Harthi, L; Henderson, LJ; Major, EO; Monaco, MC; Sharma, A	1
Aliprandi, A; Ferrarese, C; Longoni, M; Stanzani, L; Tremolizzo, L	1
Bauer, M; Cotter, RL; Erichsen, D; Gendelman, HE; Ghorpade, A; Lopez, AL; Morgello, S; Niemann, D; Peng, H; Ryan, LA; Williams, C; Zheng, J	1
Berman, JW; Calderon, TM; D'Aversa, TG; Eugenin, EA; Lopez, L	1
Brooke, SM; Lim, MC; Sapolsky, RM	1
Cotter, RL; Curthoys, NP; Erichsen, D; Herek, S; Lopez, AL; Zhao, J; Zheng, J	1
Chang, L; Conant, K; Ernst, T; St Hillaire, C	1
Acheampong, E; Mukhtar, M; Parveen, Z; Pomerantz, RJ	1
English, R; Meeker, R; Tompkins, M	1
Alesse, E; Angelucci, A; Cifone, G; De Simone, C; Famularo, G; Moretti, S; Santini, G; Trinchieri, V	1
Curthoys, N; Erdmann, N; Ferraris, D; Herek, S; Hexum, TD; Lopez, AL; Tsukamoto, T; Zhao, J; Zheng, J	1
Brambilla, L; Rossi, D; Vesce, S; Volterra, A	1
Cao, Z; Erdmann, N; Peng, H; Tian, C; Zhao, J; Zheng, J	1
González, RG; Halpern, EF; Lee, V; Lentz, MR; Ratai, EM; Westmoreland, SV	1
Dawson, TM; Dawson, VL	1
Benos, DJ; Benveniste, EN; Bubien, JK; Hahn, BH; Shaw, GM	1
Matsumoti, M; Strnat, MA; Wiley, CA; Zornow, MH	1
Bradley, WG; Nagano, I; Nakamura, S; Shapshak, P; Srivastava, AK; Stewart, RV; Xin, KQ; Yoshioka, M	1
Epstein, LG; Gelbard, HA	1
De Micheli, A; Dolara, A; Ferrarese, C; Frattola, L; Riva, R	1
Gurwitz, D; Kloog, Y	1
Doble, A	1
Basile, AS; Ellis, RJ; Espey, MG; Heaton, RK	2
Hutson, PH; Reynolds, GP; Sardar, AM	1
Anderson, C; Bell, JE; Geiger, JD; Haughey, NJ; Jones, M; Nath, A	1
Wang, YS; White, TD	1
Bauer, M; Gendelman, HE; Heyes, MP; Jiang, ZG; Markey, SP; Murphy, C; Piggee, C; Quearry, B; Zheng, J	1
Belmadani, A; Collins, MA; Neafsey, EJ; Schipma, MJ; Zou, JY	1
Koutsilieri, E; Riederer, P; ter Meulen, V	1
Aliprandi, A; De Micheli, A; Dolara, A; Ferrarese, C; Frattola, L; Stanzani, L; Tremolizzo, L	1
Arendt, G; Köller, H; Schaal, H; von Giesen, HJ	1
Arendt, G; Freund, M; Garrido, SR; Köller, H; Ott, M; Rosenbaum, C; Schaal, H; von Giesen, HJ	1
Du, F; Schwarcz, R	1

Reviews

13 review(s) available for glutamic acid and AIDS Dementia Complex

Article	Year
The far-reaching HAND of cART: cART effects on astrocytes. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2021, Volume: 16, Issue:1 Topics: Aging; AIDS Dementia Complex; Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Astrocytes; Calcium; Cellular Senescence; Central Nervous System; Glucose; Glutamic Acid; Glutamine; HIV Infections; HIV-1; Humans; Mitochondria; Neurocognitive Disorders; Oxidative Stress; Phenotype; Prevalence; Rats	2021
Targeting the glutamatergic system for the treatment of HIV-associated neurocognitive disorders. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2013, Volume: 8, Issue:3 Topics: AIDS Dementia Complex; Animals; Cognition Disorders; Drug Delivery Systems; Excitatory Amino Acid Antagonists; Glutamic Acid; HIV Infections; Humans; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Treatment Outcome	2013
Glutamate metabolism and HIV-associated neurocognitive disorders. Journal of neurovirology, 2014, Volume: 20, Issue:4 Topics: AIDS Dementia Complex; Animals; Glutamic Acid; HIV-1; Humans	2014
HIV-1, methamphetamine and astrocyte glutamate regulation: combined excitotoxic implications for neuro-AIDS. Current HIV research, 2012, Volume: 10, Issue:5 Topics: Acquired Immunodeficiency Syndrome; AIDS Dementia Complex; Amino Acid Transport System X-AG; Astrocytes; Blood-Brain Barrier; Central Nervous System Stimulants; Disease Progression; Excitatory Amino Acid Transporter 2; Female; Gene Expression Regulation; Glutamic Acid; Humans; Male; Methamphetamine; Neurotransmitter Agents; Substance Abuse, Intravenous	2012
T-Cells and excitotoxicity: HIV-1 and other neurodegenerative disorders. Neuromolecular medicine, 2005, Volume: 7, Issue:3 Topics: AIDS Dementia Complex; Animals; Brain; CD4-Positive T-Lymphocytes; Excitatory Amino Acids; Glutamic Acid; HIV-1; Humans; Immune Tolerance; Multiple Sclerosis; Neurodegenerative Diseases	2005
Glutamate release from astrocytes in physiological conditions and in neurodegenerative disorders characterized by neuroinflammation. International review of neurobiology, 2007, Volume: 82 Topics: AIDS Dementia Complex; Alzheimer Disease; Animals; Astrocytes; Calcium; Glutamic Acid; Humans; Inflammation; Neurodegenerative Diseases	2007
gp120 neurotoxicity in primary cortical cultures. Advances in neuroimmunology, 1994, Volume: 4, Issue:3 Topics: AIDS Dementia Complex; Amino Acid Oxidoreductases; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Cerebral Cortex; Cytokines; Cytopathogenic Effect, Viral; Eicosanoids; Excitatory Amino Acid Antagonists; Glutamic Acid; HIV Envelope Protein gp120; HIV-1; Humans; Neurons; Nitric Oxide Synthase; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase; Superoxides	1994
gp120-mediated alterations in astrocyte ion transport. Advances in neuroimmunology, 1994, Volume: 4, Issue:3 Topics: AIDS Dementia Complex; Amiloride; Animals; Astrocytes; Biological Transport; Glutamic Acid; HIV Envelope Protein gp120; Nerve Tissue Proteins; Potassium; Rats; Sodium; Sodium-Hydrogen Exchangers	1994
Role of immune activation and cytokine expression in HIV-1-associated neurologic diseases. Advances in neuroimmunology, 1995, Volume: 5, Issue:3 Topics: AIDS Dementia Complex; Apoptosis; Cell Adhesion; Cytokines; Endothelium, Vascular; Glutamic Acid; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Lymphocyte Subsets; Macrophages; Neuroglia; Neurons; Nitric Oxide; Peripheral Nervous System Diseases; Quinolinic Acid; Receptors, Glutamate	1995
HIV-1 encephalopathy in children. Current opinion in pediatrics, 1995, Volume: 7, Issue:6 Topics: Adult; AIDS Dementia Complex; Animals; Brain; Cell Death; Child; Gene Products, tat; Glutamic Acid; HIV Envelope Protein gp120; HIV-1; Humans; Infant; Neurons; Neurotoxins; Oxidative Stress; tat Gene Products, Human Immunodeficiency Virus; Tumor Necrosis Factor-alpha	1995
The role of excitotoxicity in neurodegenerative disease: implications for therapy. Pharmacology & therapeutics, 1999, Volume: 81, Issue:3 Topics: AIDS Dementia Complex; Amyotrophic Lateral Sclerosis; Calcium; Excitatory Amino Acids; Glutamic Acid; Humans; N-Methylaspartate; Neurodegenerative Diseases; Neurotransmitter Agents	1999
Neurotransmission in HIV associated dementia: a short review. Journal of neural transmission (Vienna, Austria : 1996), 2001, Volume: 108, Issue:6 Topics: Acetylcholine; AIDS Dementia Complex; Dopamine; Glutamic Acid; Humans; Synaptic Transmission	2001
Quinolinic acid and kynurenic acid in the mammalian brain. Advances in experimental medicine and biology, 1991, Volume: 294 Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; AIDS Dementia Complex; Animals; Aspartic Acid; Biological Transport; Brain Chemistry; Brain Diseases; Dioxygenases; Epilepsy, Temporal Lobe; Glutamates; Glutamic Acid; Humans; Kynurenic Acid; Kynurenine; Lyases; Nerve Degeneration; Oxygenases; Quinolinic Acid; Quinolinic Acids; Rats; Receptors, Neurotransmitter; Transaminases	1991

Trials

2 trial(s) available for glutamic acid and AIDS Dementia Complex

Article	Year
Impact of minocycline on cerebrospinal fluid markers of oxidative stress, neuronal injury, and inflammation in HIV-seropositive individuals with cognitive impairment. Journal of neurovirology, 2014, Volume: 20, Issue:6 Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; AIDS Dementia Complex; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Ceramides; Cytokines; Double-Blind Method; Female; Glutamic Acid; HIV-1; Humans; Kynurenine; Male; Middle Aged; Minocycline; Neurofilament Proteins; Neurons; Neuroprotective Agents; Nitric Oxide Synthase Type II; Oxidative Stress	2014
Antiretroviral treatment alters relationship between MCP-1 and neurometabolites in HIV patients. Antiviral therapy, 2004, Volume: 9, Issue:3 Topics: Adult; AIDS Dementia Complex; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Brain; Brain Chemistry; CD4 Lymphocyte Count; Chemokine CCL2; Choline; Creatine; Female; Glutamic Acid; Glutamine; HIV Infections; HIV-1; Humans; Immunoenzyme Techniques; Inositol; Magnetic Resonance Spectroscopy; Male; Prospective Studies; Viral Load	2004

Article

Year

Impact of minocycline on cerebrospinal fluid markers of oxidative stress, neuronal injury, and inflammation in HIV-seropositive individuals with cognitive impairment.

Journal of neurovirology, 2014, Volume: 20, Issue:6

Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; AIDS Dementia Complex; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Ceramides; Cytokines; Double-Blind Method; Female; Glutamic Acid; HIV-1; Humans; Kynurenine; Male; Middle Aged; Minocycline; Neurofilament Proteins; Neurons; Neuroprotective Agents; Nitric Oxide Synthase Type II; Oxidative Stress

2014

Antiretroviral treatment alters relationship between MCP-1 and neurometabolites in HIV patients.

Antiviral therapy, 2004, Volume: 9, Issue:3

Topics: Adult; AIDS Dementia Complex; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Brain; Brain Chemistry; CD4 Lymphocyte Count; Chemokine CCL2; Choline; Creatine; Female; Glutamic Acid; Glutamine; HIV Infections; HIV-1; Humans; Immunoenzyme Techniques; Inositol; Magnetic Resonance Spectroscopy; Male; Prospective Studies; Viral Load

2004

Other Studies

35 other study(ies) available for glutamic acid and AIDS Dementia Complex

Article	Year
Pananx notoginseng saponins attenuate CCL2-induced cognitive deficits in rats via anti-inflammation and anti-apoptosis effects that involve suppressing over-activation of NMDA receptors. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 127 Topics: AIDS Dementia Complex; Animals; Anti-Inflammatory Agents; Apoptosis; Chemokine CCL2; Cognitive Dysfunction; Glutamic Acid; Hippocampus; Male; Neuroprotective Agents; Panax notoginseng; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Saponins; Superoxide Dismutase	2020
Progressive cerebral injury in the setting of chronic HIV infection and antiretroviral therapy. Journal of neurovirology, 2013, Volume: 19, Issue:3 Topics: Adult; AIDS Dementia Complex; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Aspartic Acid; Basal Ganglia; Cerebral Cortex; Choline; Cognition; Disease Progression; Female; Glutamic Acid; HIV; Humans; Inositol; Male; Middle Aged; Neuropsychological Tests	2013
Small molecule glutaminase inhibitors block glutamate release from stimulated microglia. Biochemical and biophysical research communications, 2014, Jan-03, Volume: 443, Issue:1 Topics: AIDS Dementia Complex; Animals; Biological Assay; Brain Ischemia; Cells, Cultured; Drug Evaluation, Preclinical; Glutamic Acid; Glutaminase; Mice; Microglia; Multiple Sclerosis; Neuroprotective Agents; Small Molecule Libraries; Tetradecanoylphorbol Acetate; Toll-Like Receptors; Tumor Necrosis Factor-alpha	2014
Astrocyte elevated gene-1 is a novel modulator of HIV-1-associated neuroinflammation via regulation of nuclear factor-κB signaling and excitatory amino acid transporter-2 repression. The Journal of biological chemistry, 2014, Jul-11, Volume: 289, Issue:28 Topics: AIDS Dementia Complex; Animals; Astrocytes; Brain; Cell Adhesion Molecules; Down-Regulation; Excitatory Amino Acid Transporter 2; Female; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; HIV-1; Humans; Inflammation; Interleukin-1beta; Male; Membrane Glycoproteins; Membrane Proteins; Mice; Mice, Transgenic; RNA-Binding Proteins; Signal Transduction; tat Gene Products, Human Immunodeficiency Virus; Transcription Factor RelA; YY1 Transcription Factor	2014
Neurometabolite Alterations Associated With Cognitive Performance in Perinatally HIV-Infected Children. Medicine, 2016, Volume: 95, Issue:12 Topics: Adolescent; AIDS Dementia Complex; Aspartic Acid; Brain; CD4 Lymphocyte Count; Child; Choline; Cognition Disorders; Cohort Studies; Creatine; Cross-Sectional Studies; Female; Glutamic Acid; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Inositol; Magnetic Resonance Spectroscopy; Male; Neurofilament Proteins; Neuropsychological Tests; Reference Values; tau Proteins	2016
Pilot Assessment of Brain Metabolism in Perinatally HIV-Infected Youths Using Accelerated 5D Echo Planar J-Resolved Spectroscopic Imaging. PloS one, 2016, Volume: 11, Issue:9 Topics: Adolescent; AIDS Dementia Complex; Algorithms; Anti-HIV Agents; Aspartic Acid; Brain; Case-Control Studies; Choline; Creatine; Echo-Planar Imaging; Energy Metabolism; Female; Functional Neuroimaging; Glutamic Acid; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Pilot Projects; Young Adult	2016
Reduced expression of excitatory amino acid transporter 2 and diffuse microglial activation in the cerebral cortex in AIDS cases with or without HIV encephalitis. Journal of neuropathology and experimental neurology, 2009, Volume: 68, Issue:2 Topics: Acquired Immunodeficiency Syndrome; AIDS Dementia Complex; Astrocytes; Biomarkers; Cerebral Cortex; Cytoprotection; Down-Regulation; Excitatory Amino Acid Transporter 2; Gliosis; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; HIV Core Protein p24; Humans; Immunohistochemistry; Interleukin-1beta; Microglia; Nerve Degeneration; Tumor Necrosis Factor-alpha	2009
In vitro glutaminase regulation and mechanisms of glutamate generation in HIV-1-infected macrophage. Journal of neurochemistry, 2009, Volume: 109, Issue:2 Topics: AIDS Dementia Complex; Cells, Cultured; Glutamic Acid; Glutaminase; HIV Infections; HIV-1; Humans; Macrophages	2009
Changes in MRS neuronal markers and T cell phenotypes observed during early HIV infection. Neurology, 2009, Apr-28, Volume: 72, Issue:17 Topics: Adult; AIDS Dementia Complex; Aspartic Acid; Biomarkers; Brain; CD4-CD8 Ratio; Disease Progression; Early Diagnosis; Frontal Lobe; Glutamic Acid; HIV Seropositivity; Humans; Immunophenotyping; Magnetic Resonance Spectroscopy; Middle Aged; Neurons; T-Lymphocytes	2009
Lower brain glutamate is associated with cognitive deficits in HIV patients: a new mechanism for HIV-associated neurocognitive disorder. Journal of magnetic resonance imaging : JMRI, 2010, Volume: 32, Issue:5 Topics: Adult; AIDS Dementia Complex; Brain; Cognition Disorders; Female; Glutamic Acid; HIV Infections; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged	2010
Interferon-α regulates glutaminase 1 promoter through STAT1 phosphorylation: relevance to HIV-1 associated neurocognitive disorders. PloS one, 2012, Volume: 7, Issue:3 Topics: AIDS Dementia Complex; Animals; Base Sequence; Brain; Cells, Cultured; Dose-Response Relationship, Drug; Gene Expression Regulation; Glutamic Acid; Glutaminase; HEK293 Cells; HIV Infections; HIV-1; Host-Pathogen Interactions; Humans; Interferon-alpha; Isoenzymes; Macrophages; Molecular Sequence Data; Monocytes; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Rats; Reverse Transcriptase Polymerase Chain Reaction; STAT1 Transcription Factor	2012
Human immunodeficiency virus type 1 (HIV-1) transactivator of transcription through its intact core and cysteine-rich domains inhibits Wnt/β-catenin signaling in astrocytes: relevance to HIV neuropathogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Nov-14, Volume: 32, Issue:46 Topics: AIDS Dementia Complex; Astrocytes; beta Catenin; Blotting, Western; Cell Line; Cysteine; Flow Cytometry; Gene Products, tat; Genes, Reporter; Glutamic Acid; HIV-1; Humans; Immunoprecipitation; Luciferases; Plasmids; Point Mutation; Real-Time Polymerase Chain Reaction; rev Gene Products, Human Immunodeficiency Virus; Signal Transduction; Transfection; Wnt Proteins	2012
Glutamate may be the soluble cerebrospinal fluid factor that induces calcium dysregulation in cultured astrocytes in HIV dementia. AIDS (London, England), 2002, Aug-16, Volume: 16, Issue:12 Topics: AIDS Dementia Complex; Astrocytes; Calcium; Cells, Cultured; Glutamic Acid; Humans	2002
Neuronal injury regulates fractalkine: relevance for HIV-1 associated dementia. Journal of neuroimmunology, 2003, Volume: 138, Issue:1-2 Topics: Adult; AIDS Dementia Complex; Astrocytes; Cells, Cultured; Chemokine CX3CL1; Chemokines, CX3C; Fetus; Glutamic Acid; HIV-1; Humans; Membrane Proteins; Middle Aged; Neurons; Recombinant Proteins; Tumor Necrosis Factor-alpha; Up-Regulation; Viral Proteins; Virion	2003
MCP-1 (CCL2) protects human neurons and astrocytes from NMDA or HIV-tat-induced apoptosis. Journal of neurochemistry, 2003, Volume: 85, Issue:5 Topics: AIDS Dementia Complex; Apoptosis; Astrocytes; Cells, Cultured; Chemokine CCL2; Chemokine CCL5; Coculture Techniques; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gene Products, tat; Glutamic Acid; Humans; N-Methylaspartate; Neurons; Neuroprotective Agents; Receptors, N-Methyl-D-Aspartate; tat Gene Products, Human Immunodeficiency Virus	2003
gp120 neurotoxicity fails to induce heat shock defenses, while the over expression of hsp70 protects against gp120. Brain research bulletin, 2003, Jul-15, Volume: 61, Issue:2 Topics: AIDS Dementia Complex; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Female; Gene Expression; Glutamic Acid; Hippocampus; HIV Envelope Protein gp120; Hot Temperature; HSP70 Heat-Shock Proteins; Immunoblotting; Immunoenzyme Techniques; Infections; Pregnancy; Rats; Rats, Sprague-Dawley; Time Factors	2003
Mitochondrial glutaminase enhances extracellular glutamate production in HIV-1-infected macrophages: linkage to HIV-1 associated dementia. Journal of neurochemistry, 2004, Volume: 88, Issue:1 Topics: AIDS Dementia Complex; Anti-HIV Agents; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media, Conditioned; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Space; Glutamic Acid; Glutaminase; Glutamine; HIV Infections; HIV-1; Humans; Macrophages; Mitochondria; Monocytes; RNA, Messenger; Zidovudine	2004
Enhanced Excitotoxicity in Primary Feline Neural Cultures Exposed to Feline Immunodeficiency Virus (FIV). Journal of neuro-AIDS, 1997, Volume: 1, Issue:3 Topics: Acquired Immunodeficiency Syndrome; AIDS Dementia Complex; Animals; Astrocytes; Cats; Feline Acquired Immunodeficiency Syndrome; Glutamic Acid; Humans; Immunodeficiency Virus, Feline; Microglia; Neurons	1997
Reduction of glutamate levels in HIV-infected subjects treated with acetylcarnitine. Journal of neuro-AIDS, 1999, Volume: 2, Issue:2 Topics: Acetylcarnitine; Adult; AIDS Arteritis, Central Nervous System; AIDS Dementia Complex; CD4 Lymphocyte Count; Female; Glutamic Acid; HIV Infections; Humans; Male; Middle Aged; Nootropic Agents	1999
Glutamate production by HIV-1 infected human macrophage is blocked by the inhibition of glutaminase. Journal of neurochemistry, 2007, Volume: 102, Issue:2 Topics: AIDS Dementia Complex; Biological Assay; Cell Survival; Cells, Cultured; Enzyme Inhibitors; Glutamic Acid; Glutaminase; HIV-1; Humans; Macrophages; RNA, Small Interfering	2007
HIV-infected macrophages mediate neuronal apoptosis through mitochondrial glutaminase. Journal of neurochemistry, 2008, Volume: 105, Issue:3 Topics: AIDS Dementia Complex; Animals; Apoptosis; Brain; Caspases; Cell Cycle; Cells, Cultured; Culture Media, Conditioned; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Glutaminase; Glutamine; Humans; Macrophages; Mitochondria; Monocytes; Nerve Degeneration; Neurons; Neurotoxins; Rats	2008
Metabolic markers of neuronal injury correlate with SIV CNS disease severity and inoculum in the macaque model of neuroAIDS. Magnetic resonance in medicine, 2008, Volume: 59, Issue:3 Topics: AIDS Dementia Complex; Analysis of Variance; Animals; Aspartic Acid; Choline; Creatine; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Inositol; Linear Models; Macaca mulatta; Magnetic Resonance Spectroscopy; Severity of Illness Index; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus	2008
Intracerebral injection of tumor necrosis factor-alpha does not increase brain concentrations of glutamate. AIDS (London, England), 1993, Volume: 7, Issue:12 Topics: AIDS Dementia Complex; Animals; Brain; Glutamates; Glutamic Acid; Rabbits; Tumor Necrosis Factor-alpha	1993
Elevated glutamate in the cerebrospinal fluid of patients with HIV dementia. JAMA, 1997, Feb-26, Volume: 277, Issue:8 Topics: AIDS Dementia Complex; Glutamic Acid; Humans	1997
Elevated cerebrospinal fluid glutamate in patients with HIV-related dementia. JAMA, 1997, Jun-25, Volume: 277, Issue:24 Topics: AIDS Dementia Complex; Glutamic Acid; Humans; Tumor Necrosis Factor-alpha	1997
Relevance of glutamate levels in the CSF of patients with HIV-1-associated dementia complex. Neurology, 1999, Sep-22, Volume: 53, Issue:5 Topics: AIDS Dementia Complex; Chromatography, High Pressure Liquid; Female; Glutamic Acid; HIV-1; Humans; Male	1999
Deficits of NMDA receptors and glutamate uptake sites in the frontal cortex in AIDS. Neuroreport, 1999, Nov-26, Volume: 10, Issue:17 Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS Dementia Complex; Aminoquinolines; Aspartic Acid; Binding Sites; Excitatory Amino Acid Antagonists; Frontal Lobe; Glutamic Acid; Humans; Kinetics; Matched-Pair Analysis; Receptors, N-Methyl-D-Aspartate; Thermodynamics	1999
Synergistic neurotoxicity by human immunodeficiency virus proteins Tat and gp120: protection by memantine. Annals of neurology, 2000, Volume: 47, Issue:2 Topics: AIDS Dementia Complex; Brain; Calcium; Cell Survival; Cells, Cultured; Drug Synergism; Encephalitis; Fetus; Gene Products, tat; Glutamic Acid; HIV Envelope Protein gp120; Humans; Intracellular Fluid; Memantine; Neurons; Neuroprotective Agents; tat Gene Products, Human Immunodeficiency Virus; Time Factors	2000
The HIV glycoproteins gp41 and gp120 cause rapid excitation in rat cortical slices. Neuroscience letters, 2000, Sep-08, Volume: 291, Issue:1 Topics: Adenosine; AIDS Dementia Complex; Animals; Extracellular Space; Glutamic Acid; HIV Envelope Protein gp120; HIV Envelope Protein gp41; HIV-1; In Vitro Techniques; Male; Norepinephrine; Parietal Lobe; Perfusion; Rats; Rats, Sprague-Dawley	2000
Glutamate is a mediator of neurotoxicity in secretions of activated HIV-1-infected macrophages. Journal of neuroimmunology, 2001, Jul-02, Volume: 117, Issue:1-2 Topics: AIDS Dementia Complex; Animals; Cells, Cultured; Glutamic Acid; HIV-1; Humans; Lipopolysaccharides; Macrophage Activation; Macrophages; Rats; Receptors, N-Methyl-D-Aspartate; Trypsin	2001
Ethanol pre-exposure suppresses HIV-1 glycoprotein 120-induced neuronal degeneration by abrogating endogenous glutamate/Ca2+-mediated neurotoxicity. Neuroscience, 2001, Volume: 104, Issue:3 Topics: AIDS Dementia Complex; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Calcium; Drug Interactions; Ethanol; Glial Fibrillary Acidic Protein; Glutamic Acid; Hippocampus; HIV Envelope Protein gp120; Immunohistochemistry; Interleukin-6; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tritium	2001
Increased glutamate in CSF and plasma of patients with HIV dementia. Neurology, 2001, Aug-28, Volume: 57, Issue:4 Topics: Adult; AIDS Dementia Complex; Alzheimer Disease; Analysis of Variance; Atrophy; Brain; Female; Glutamic Acid; Humans; Linear Models; Male; Middle Aged; Nervous System Diseases	2001
Soluble cerebrospinal fluid factors induce Ca2+ dysregulation in rat cultured cortical astrocytes in HIV-1-associated dementia complex. AIDS (London, England), 2001, Sep-28, Volume: 15, Issue:14 Topics: AIDS Dementia Complex; Animals; Astrocytes; Biomarkers; Calcium; Cells, Cultured; Cerebral Cortex; Cerebrospinal Fluid; Glutamic Acid; Humans; Rats; Rats, Wistar; Solubility	2001
HIV-1 protein Tat reduces the glutamate-induced intracellular Ca2+ increase in cultured cortical astrocytes. The European journal of neuroscience, 2001, Volume: 14, Issue:11 Topics: Adenosine Triphosphate; AIDS Dementia Complex; Animals; Animals, Newborn; Astrocytes; Calcium; Cell Extracts; Central Nervous System; Dose-Response Relationship, Drug; Gene Expression Regulation; Gene Expression Regulation, Viral; Gene Products, tat; Glutamic Acid; HIV-1; Intracellular Fluid; Rats; Rats, Wistar; tat Gene Products, Human Immunodeficiency Virus; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	2001
Increased glutamate in CSF and plasma of patients with HIV dementia. Neurology, 2002, May-14, Volume: 58, Issue:9 Topics: AIDS Dementia Complex; Artifacts; Glutamic Acid; Humans; Hydrolysis; Perchlorates; Reproducibility of Results; Research Design	2002