glutamic acid and ACY2 Deficiency

glutamic acid has been researched along with ACY2 Deficiency in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's10 (90.91)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Attwell, D; Hamilton, NB; Káradóttir, R; Kolodziejczyk, K; Wade, A1
Campbell, GA; Ezell, EL; Matalon, R; Michals-Matalon, K; Quast, MJ; Rady, PL; Rassin, DK; Surendran, S; Szucs, S; Tyring, SK; Wei, J1
Matalon, KM; Matalon, R; Surendran, S; Szucs, S; Tyring, SK1
Matalon, R; Michals-Matalon, K; Surendran, S; Tyring, SK1
Bhattacharya, P; Harris, K; Lin, A; Ross, B; Tran, T; Wong, W1
de Vellis, J; Kumar, S; Mattan, NS1
Berrin, JG; Giardina, T; Herga, S; Perrier, J; Puigserver, A1
Auberson, M; Blanz, J; Hübner, CA; Jentsch, TJ; Maier, H; Muenscher, A; Schweizer, M1
Blüml, S1
Blüml, S; Hwang, JH; Moreno, A; Ross, BD1
Blüml, S; Moreno, A; Ross, BD1

Reviews

2 review(s) available for glutamic acid and ACY2 Deficiency

ArticleYear
Canavan disease: studies on the knockout mouse.
    Advances in experimental medicine and biology, 2006, Volume: 576

    Topics: Amidohydrolases; Animals; Canavan Disease; Dipeptides; gamma-Aminobutyric Acid; Gene Targeting; Genetic Therapy; Glutamic Acid; Humans; Mice; Mice, Knockout; Phenotype; Stem Cell Transplantation

2006
Canavan disease: a white matter disorder.
    Mental retardation and developmental disabilities research reviews, 2006, Volume: 12, Issue:2

    Topics: Aspartic Acid; Biomarkers; Brain; Canavan Disease; Diagnosis, Differential; Genetic Counseling; Glutamic Acid; Homeostasis; Humans; Infant; Magnetic Resonance Imaging; Myelin Sheath; Neuroglia; Neurons; Oligodendroglia

2006

Trials

1 trial(s) available for glutamic acid and ACY2 Deficiency

ArticleYear
Direct determination of the N-acetyl-L-aspartate synthesis rate in the human brain by (13)C MRS and [1-(13)C]glucose infusion.
    Journal of neurochemistry, 2001, Volume: 77, Issue:1

    Topics: Adult; Amidohydrolases; Aspartic Acid; Brain; Canavan Disease; Carbon Isotopes; Child, Preschool; Glucose; Glutamic Acid; Humans; Infusions, Intravenous; Intubation, Gastrointestinal; Magnetic Resonance Spectroscopy; Predictive Value of Tests

2001

Other Studies

8 other study(ies) available for glutamic acid and ACY2 Deficiency

ArticleYear
The effect of N-acetyl-aspartyl-glutamate and N-acetyl-aspartate on white matter oligodendrocytes.
    Brain : a journal of neurology, 2009, Volume: 132, Issue:Pt 6

    Topics: Action Potentials; Animals; Aspartic Acid; Calcium; Canavan Disease; Cerebellum; Dipeptides; Evoked Potentials; Glutamic Acid; Hydrolysis; Oligodendroglia; Patch-Clamp Techniques; Pelizaeus-Merzbacher Disease; Rats; Receptors, N-Methyl-D-Aspartate; Tissue Culture Techniques

2009
Expression of glutamate transporter, GABRA6, serine proteinase inhibitor 2 and low levels of glutamate and GABA in the brain of knock-out mouse for Canavan disease.
    Brain research bulletin, 2003, Aug-30, Volume: 61, Issue:4

    Topics: Amino Acid Transport System X-AG; Analysis of Variance; Animals; Azo Compounds; Brain Chemistry; Canavan Disease; Creatine; Dipeptides; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Insect Proteins; Magnetic Resonance Spectroscopy; Mice; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, Protein

2003
Metabolic changes in the knockout mouse for Canavan's disease: implications for patients with Canavan's disease.
    Journal of child neurology, 2003, Volume: 18, Issue:9

    Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Body Weight; Canavan Disease; Disease Models, Animal; Glutamic Acid; Humans; Mice; Mice, Knockout

2003
Regulation of NAA-synthesis in the human brain in vivo: Canavan's disease, Alzheimer's disease and schizophrenia.
    Advances in experimental medicine and biology, 2006, Volume: 576

    Topics: Alzheimer Disease; Aspartic Acid; Brain; Canavan Disease; Child; Glutamic Acid; Humans; Magnetic Resonance Imaging; Molecular Structure; Schizophrenia

2006
Identification of the zinc binding ligands and the catalytic residue in human aspartoacylase, an enzyme involved in Canavan disease.
    FEBS letters, 2006, Oct-30, Volume: 580, Issue:25

    Topics: Amidohydrolases; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Canavan Disease; Catalytic Domain; DNA, Complementary; Escherichia coli; Glutamic Acid; Histidine; Humans; In Vitro Techniques; Kinetics; Ligands; Models, Molecular; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Recombinant Proteins; Sequence Homology, Amino Acid; Zinc

2006
Leukoencephalopathy upon disruption of the chloride channel ClC-2.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Jun-13, Volume: 27, Issue:24

    Topics: Age Factors; Animals; Axons; Blood-Brain Barrier; Brain; Brain Diseases; Canavan Disease; Chloride Channels; CLC-2 Chloride Channels; Demyelinating Diseases; Epilepsy; Glutamic Acid; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Mutation; Myelin Sheath; RNA, Complementary; Subcellular Fractions; Time Factors; Up-Regulation; Vacuoles

2007
In vivo quantitation of cerebral metabolite concentrations using natural abundance 13C MRS at 1.5 T.
    Journal of magnetic resonance (San Diego, Calif. : 1997), 1999, Volume: 136, Issue:2

    Topics: Aspartic Acid; Brain; Canavan Disease; Carbon Isotopes; Child; Child, Preschool; Glutamic Acid; Glutamine; Humans; Hydrogen Bonding; Infant; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Sensitivity and Specificity; Spin Labels; Synaptic Transmission

1999
1-(13)C glucose magnetic resonance spectroscopy of pediatric and adult brain disorders.
    NMR in biomedicine, 2001, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Diseases; Canavan Disease; Carbon Isotopes; Child; Child, Preschool; Female; Glucose; Glutamic Acid; Hepatic Encephalopathy; Humans; Infant, Newborn; Infant, Premature; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged

2001