gluma and Tooth-Erosion

Cervical tooth erosion is increasingly observed among adults and frequently associated with dentin sensitivity (DS). This study evaluated the effectiveness on DS of a biomimetic mineralization system (BIMIN) in comparison to the current standard treatment (Gluma(®) Desensitizer, Gluma).. In this single-blind, 2-arm study, 40 patients with confirmed cervical DS were randomized to either the test group or the positive control group. A Visual-Analog-Scale (VAS) was used to assess DS following stimulation of the exposed dentin with a 2-s air blast. Assessments were made at baseline (pre-treatment), 2 days, 4, 8 and 12 weeks, and 12 months after treatment. Two-stage replicas were obtained from the treated teeth and gold sputtered at baseline, and 2 days, 3 and 12 months after treatment. Surface topography of the treated cervical lesions and occlusion of dentinal tubules were investigated using scanning electron microscopy (SEM).. Both treatments led to a statistically significant reduction (P<0.0001) in DS that persisted over the entire 12-month observation period. Differences in DS between the treatments were not statistically significant. SEM photomicrographs demonstrated that a mineral layer concealed the dentinal tubules in the test group. In contrast, numerous dentinal tubules remained visible in cervical defects that were treated with Gluma.. A biomimetic mineralization kit was successfully used to treat patients exhibiting DS. The effect was similar to using Gluma, and was likely the result of the deposition of an enamel-like layer on the exposed cervical dentin.

Topics: Adult; Aged; Apatites; Biomimetic Materials; Calcium; Dentin; Dentin Desensitizing Agents; Dentin Permeability; Dentin Sensitivity; Female; Fluorides; Glutaral; Humans; Male; Microscopy, Electron, Scanning; Middle Aged; Phosphates; Polymethacrylic Acids; Replica Techniques; Single-Blind Method; Tooth Cervix; Tooth Erosion; Tooth Remineralization; Treatment Outcome; Young Adult

This study investigated the desensitizing effect of topically-applied Gluma on sensitive cervical erosion lesions. A total of 46 teeth exhibiting moderate to severe sensitivity to cold and instrumentation, in 15 patients, were included in the study. Mildly sensitive teeth and teeth with cervical caries lesions were excluded from the study. After each tooth was isolated with rubber dam, investigators applied cold air, as well as tactile stimuli using an explorer, and recorded the baseline responses. Nine of the 46 teeth then received Gluma primer only (group 1), 15 received cleanser followed by primer (group 2), 15 received cleanser followed by primer and sealer (group 3), and seven received a placebo (group 4). After two weeks, the teeth in group 4 were randomly placed in one of the other three groups. The responses of the teeth in each group to various stimuli were recorded immediately after the application of test materials, and subsequently at one week, two weeks, one month, three months, six months and one year. Statistical analysis indicates that the three treatment groups all showed significant differences compared to the untreated control group (p < .001). A reduction of sensitivity was noted immediately after primer, cleanser-primer, or cleanser-primer-sealer was applied. Treatment groups 2 and 3 demonstrated less sensitivity than group 1 (p = .02; p = .03, respectively). At the one-year recall, the observed order of treatment effectiveness by group was 2, 3, 1. In approximately 50 per cent of the teeth treated in the study, remission of sensitivity was seen after one year. All of the remaining teeth exhibited some relief of sensitivity. The treatments' success was found to be inversely proportional to the severity of the initial response.

Topics: Adult; Dentin Permeability; Dentin Sensitivity; Dentinal Fluid; Fluid Shifts; Glutaral; Humans; Middle Aged; Polymethacrylic Acids; Resin Cements; Tooth Cervix; Tooth Erosion; Treatment Outcome

To study the clinical performance of two candidates for improvement of the original Gluma bonding system.. Eight teeth with cervical buccal abrasion/erosion lesions were identified in 40 patients. The lesions were conditioned with an oxalic acid solution followed by either a HEMA-glutaraldehyde bonding agent or a formamide-containing bonding agent. The lesions were restored with a hybrid composite. Each patient received the same number of restorations with the two different bonding formulations. All restorations were made by the same operator (JK). Evaluations were based on the USPHS system.. No difference between the two groups as to retention, marginal adaptation and discoloration was observed after 3 years. Eight restorations were lost and a slight increase in marginal discoloration was seen during the observation period.

Topics: Adult; Chi-Square Distribution; Color; Composite Resins; Dental Marginal Adaptation; Dental Restoration Failure; Dental Restoration, Permanent; Dentin-Bonding Agents; Female; Follow-Up Studies; Glutaral; Humans; Male; Middle Aged; Polymethacrylic Acids; Resin Cements; Tooth Abrasion; Tooth Cervix; Tooth Erosion

The new generation of dentin bonding materials can withstand the contraction shrinkage of composite materials. A two-year clinical trial of one material showed an excellent retention rate.

Topics: Aged; Color; Composite Resins; Dental Prosthesis Retention; Dental Restoration, Permanent; Dental Veneers; Dentin-Bonding Agents; Evaluation Studies as Topic; Follow-Up Studies; Glutaral; Humans; Middle Aged; Observer Variation; Polymethacrylic Acids; Surface Properties; Tooth Erosion; Tooth Root

Topics: Color; Composite Resins; Dental Leakage; Dental Restoration, Permanent; Dentin Sensitivity; Dentin-Bonding Agents; Evaluation Studies as Topic; Follow-Up Studies; Glutaral; Humans; Methacrylates; Polymethacrylic Acids; Resin Cements; Surface Properties; Tooth Erosion

This in vitro study examined the sealing ability of different desensitizing agents under a chemo-mechanical stress condition. For the study, a total of 144 extracted, caries-free human third molars were used to produce 1 mm-thick dentin discs. The specimens were divided randomly into four groups: Superseal (SS), Gluma (GL), Gluma Self-etch (GS), and Tooth Coat (TC). For each group, the permeability was measured before and after applying the desensitizer, after being exposed to Coca Cola for 5 minutes, and after 3150 strokes of a brushing abrasion. The decrease in permeability after the erosive and abrasive stress was analyzed by ANOVA and Tukey post hoc test. As a result, the dentin permeability decreased significantly for all desensitizers immediately after application (p < 0.05). SS and GS showed a significant difference in permeability reduction observed immediately after application and after acid action with Coca Cola (p < 0.05). After brushing abrasion, the permeability reduction decreased significantly for all desensitizers tested in this study (p < 0.05). TC showed the largest decrease in dentinal permeability compared to that of the other desensitizers and the differences were significant after brushing abrasion (p < 0.05). All tested desensitizers were effective in reducing dentin permeability. The behavioral characteristics under erosive and abrasive stress varied according to the products used. TC exhibited excellent sealing ability among the other desensitizers.

Topics: Dentin; Dentin Desensitizing Agents; Dentin Sensitivity; Glutaral; Humans; In Vitro Techniques; Molar, Third; Oxalic Acid; Pit and Fissure Sealants; Polymethacrylic Acids; Tooth Abrasion; Tooth Erosion

The cumulative retention rate of a microfilled resin in non-undercut cervical abrasion/erosion lesions was studied over a 5-yr period. The enamel was etched and the dentin was pretreated with either Gluma (n = 75) or the first marketed version of Scotchbond (n = 30). The cumulative 5-yr retention rate of the Gluma fillings was 90% and that of the Scotchbond fillings 47% (the 95% confidence limits were 83-98% for Gluma fillings and 27-67% for Scotchbond fillings). The retention rate with both bonding agents was significantly higher in the maxillary arch than in the mandibular arch.

Topics: Acid Etching, Dental; Bisphenol A-Glycidyl Methacrylate; Composite Resins; Dental Bonding; Dental Cavity Preparation; Dental Enamel; Dental Polishing; Dental Restoration, Permanent; Dentin; Dentin-Bonding Agents; Evaluation Studies as Topic; Follow-Up Studies; Glutaral; Humans; Materials Testing; Polymethacrylic Acids; Resin Cements; Tooth Abrasion; Tooth Erosion

Gluma and Gluma/Scotchbond were used in cervical abrasion/erosion lesions mediating a bond between a resinous restorative material and dentin. The lesions were restored without acid etching of enamel and without use of an intermediary layer of an enamel bonding agent. 142 restorations were placed. The restorations were evaluated clinically using the USPHS-system at the baseline and every half year during a 3-yr period. After 36 months the Gluma and Gluma/Scotchbond restorations showed a 14.3% and 7.4% cumulative loss of retention respectively. No secondary caries was observed during the evaluation period.

Topics: Adult; Aged; Aldehydes; Composite Resins; Dental Bonding; Dental Cements; Dental Restoration, Permanent; Glutaral; Humans; Middle Aged; Polymethacrylic Acids; Resin Cements; Stress, Mechanical; Time Factors; Tooth Abrasion; Tooth Erosion

Class V abrasion and erosion lesions restored with composite resin seem to be more susceptible to microleakage, because the gingival margin is usually placed in cementum and/or dentin. The purpose of this study was to evaluate the microleakage, in vitro, of two new dentinal bonding systems along with a positive and negative control. This study was accomplished using extracted human teeth and a calcium-45 radioisotope technique. The teeth were examined for microleakage at periods of 1 week, 6 months, and 1 year. The results at all time intervals indicated that the cavities restored with the new bonding agents and their respective composite resins leaked more than did the negative control, glass-ionomer cement.

Topics: Composite Resins; Dental Bonding; Dental Cements; Dental Leakage; Dentin; Glass Ionomer Cements; Glutaral; Humans; Maleates; Polymethacrylic Acids; Tooth Abrasion; Tooth Erosion