glucuronyl-glucosamine-glycan-sulfate and Lichen-Planus--Oral

glucuronyl-glucosamine-glycan-sulfate has been researched along with Lichen-Planus--Oral* in 2 studies

Trials

2 trial(s) available for glucuronyl-glucosamine-glycan-sulfate and Lichen-Planus--Oral

ArticleYear
Oral lichen planus: clinical and histological evaluation in an open trial using a low molecular weight heparinoid (sulodexide).
    International journal of dermatology, 2006, Volume: 45, Issue:8

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Glycosaminoglycans; Heparin, Low-Molecular-Weight; Heparinoids; Humans; Lichen Planus, Oral; Male; Middle Aged

2006
Oral erosive/ulcerative lichen planus: preliminary findings in an open trial of sulodexide compared with cyclosporine (ciclosporin) therapy.
    International journal of dermatology, 2003, Volume: 42, Issue:4

    To study the effect of the heparinoid sulodexide systemically, compared with topical cyclosporine (ciclosporin), on chronic oral erosive/ulcerative lichen planus.. An open nonrandomized trial was conducted in two groups of 10 Italian patients with lichen planus, with subjective assessment of pain and assessment of ulceration amelioration by nonblinded clinicians.. Comparable pain relief and amelioration of erosions/ulcers were seen in patients on sulodexide and in those on ciclosporin, but with faster healing in those on sulodexide.. Sulodexide appears to be as effective, and perhaps more effective, than topical ciclosporin in the therapy of oral lichen planus, and is less expensive, but full double-blind placebo-controlled studies are required.

    Topics: Adult; Anticoagulants; Cyclosporine; Female; Glycosaminoglycans; Hepatitis C; Humans; Immunosuppressive Agents; Lichen Planus, Oral; Male; Oral Ulcer; Treatment Outcome

2003