glucose-cysteine and Diabetes-Mellitus

Diabetes is a disease found in every 1 out of 4 people in the world. The glucose molecule is one of the sources of energy in the body and the lack of the digestion of glucose causes diabetes type 1 and type 2. Arginine and cysteine are nonessential amino acids that contain sulfur and help maintain the metabolisms of humans. We explored the glucose-arginine (Glc-arg) and glucose-cysteine (Glc-cys) molecules by finding their structural properties, electronic properties, chemical reactivity, mechanical strength, and transport properties because these non-essential amino acid molecules inhibit glucose-stimulated insulin secretion. Density functional theory (DFT) has been implemented to study all the properties of Glc-arg and Glc-cys using SIESTA software. Glucose-arginine (Glc-arg) inhibits a large percentage of glucose secretion and shows high chemical reactivity.

Topics: Amino Acids; Biomarkers; Blood Glucose; Cysteine; Density Functional Theory; Diabetes Mellitus; Dietary Proteins; Disease Management; Glucose; Humans; Models, Molecular; Molecular Conformation; Molecular Structure; Spectrum Analysis; Treatment Outcome