glucose, (beta-d)-isomer has been researched along with Insulin Resistance in 143 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (0.70) | 18.2507 |
| 2000's | 13 (9.09) | 29.6817 |
| 2010's | 88 (61.54) | 24.3611 |
| 2020's | 41 (28.67) | 2.80 |
| Authors | Studies |
|---|---|
| Ahuja, S; Akhtar, A; Sah, SP; Uniyal, A | 1 |
| Chen, SH; Cheng, JT; Chung, HH; Ku, PM; Wang, LY; Yu, YM | 1 |
| Bagby, GJ; Lang, CH; Petit, F | 1 |
| Muthu, K; Sundaram, R; Vasu, G | 1 |
| Bai, L; Ding, Y; Fan, Y; Fatima, M; Gao, J; Han, T; Wang, C; Zhang, Y | 1 |
| Dib, SA; Dos Santos, SS; Gabbay, MAL; Moises, RCS; Ramaldes, LA | 1 |
| Dvorakova, I; Haluzik, M; Huttl, M; Kasperova, BJ; Kratochvilova, H; Kuzma, M; Malinska, H; Markova, I; Melcova, M; Mraz, M; Oliyarnyk, O; Pelantova, H; Rosolova, K; Skop, V; Stemberkova-Hubackova, S; Svoboda, P; Trnovska, J | 1 |
| Acuna-Castillo, C; Aranda, M; Bustos, C; Calfío, C; Cubillos, FA; Del Campo, A; Díaz-Castro, F; Fajardo, A; Milla, LA; Pastene-Navarrete, ER; Rojo, LE; Salamanca, C; Troncoso, R; Villarroel, CA | 1 |
| Dludla, PV; Mazibuko-Mbeje, SE; Mthembu, SXH; Mthiyane, FT; Muller, CJF; Muvhulawa, N; Tshiitamune, A; Ziqubu, K | 1 |
| Banerjee, SK; Barge, SR; Bharadwaj, S; Borah, JC; Boruwa, J; Deka, B; Dutta, PP; Ghosh, A; Kamboj, P; Kandimalla, R; Kashyap, B; Manna, P; Pal, U; Rahman, S; Saikia, S; Samanta, SK; Sheikh, Y; Swargiary, D; Talukdar, NC; Tuli, D | 1 |
| Birkenfeld, AL; Dannecker, C; Fritsche, A; Fritsche, L; Häring, HU; Heni, M; Hummel, J; Kantartzis, K; Kullmann, S; Machann, J; Peter, A; Preissl, H; Stefan, N; Veit, R; Vosseler, A; Wagner, R | 1 |
| Haluzik, M; Hüttl, M; Malinska, H; Markova, I; Miklankova, D; Poruba, M; Vaněčkova, I; Zapletalova, I | 1 |
| Kuo, WH; Lee, CT; Lee, WC; Leung, FF; Ng, HY; Tain, YL | 1 |
| Chen, Y; Geng, X; Ji, J; Li, X; Liu, Y; Su, L; Zhao, L | 1 |
| Amarume, J; Feng, Z; Kusunoki, M; Nakamura, T; Nishina, A; Sato, D; Yano, M | 1 |
| Anno, M; Fujioka, Y; Imamura, T; Ito, Y; Izawa, S; Kato, M; Kitao, S; Matsumoto, K; Matsuzawa, K; Nakamura, R; Okura, H; Okura, T; Shoji, K; Taniguchi, SI; Ueta, E; Yamamoto, K | 1 |
| Ansari, IA; Bhatt, SP; Dutta, K; Ghosh, A; Gupta, R; Mahajan, H; Misra, A; Pandey, RM; Pandey, S; Tyagi, K; Venugopal, VK | 1 |
| Liu, X; Wang, X; Zhang, H; Zhang, Y | 1 |
| Birkenfeld, AL; Dannecker, C; Fritsche, A; Häring, HU; Heni, M; Hummel, J; Kullmann, S; Machann, J; Peter, A; Wagner, R | 1 |
| Damas-Fuentes, M; Fernández-Valero, A; Martínez-Montoro, JI; Pinzón-Martín, JL; Tinahones, FJ | 1 |
| Al-Wakeel, DE; El-Kashef, DH; Nader, MA | 1 |
| Abdallah, DM; Ahmed, KA; El-Abhar, HS; Fleifel, AM; Soubh, AA | 1 |
| Alam, MJ; Arava, S; Banerjee, SK; Bugga, P; Katare, P; Maulik, SK; Meghwani, H; Mohammed, SA | 1 |
| Fan, M; Jiang, R; Jin, W; Jing, C; Piao, C; Sun, L; Zhang, Q; Zhang, Y | 1 |
| Aly, RG; Alzaim, I; El-Mallah, A; El-Yazbi, AF; Shaaban, HH; Wahid, A | 1 |
| Barbosa-da-Silva, S; Petito-da-Silva, TI; Souza-Mello, V | 1 |
| Kang, W; Liu, Z; Niu, Y; Saadeldeen, FA; Xu, L; Xu, X | 1 |
| Chen, G; Kaneko, S; Nagashimada, M; Nagata, N; Ni, Y; Ota, T; Sakai, Y; Xu, L; Zhuge, F | 1 |
| Chatsudthipong, V; Jaikumkao, K; Lungkaphin, A; Pongchaidecha, A; Swe, MT; Thongnak, L | 1 |
| Dun, Y; Jiang, L; Li, H; Liu, S; Liu, Y; Xie, M; You, B; Zhang, W | 1 |
| Asker, ME; Hasan, RA; Keshawy, MM; Mahmoud, YK; Mohamed, HE | 1 |
| Abd El Fattah, MA; Ahmed, MAE; Eid, NI; Gamal El Din, AA; Gamil, NM; Maklad, YA | 1 |
| Chen, C; Chen, Y; Cowley, MA; Huang, L; Huang, Z; Qi, X; Veldhuis, JD; Wang, C; Zhang, Y; Zhu, S | 1 |
| Hirota, Y; Komada, H; Miura, H; Morita, Y; Nakamura, T; Ogawa, W; Okada, Y; Otowa-Suematsu, N; Sakaguchi, K; So, A; Tamori, Y; Yamada, T | 1 |
| Ebihara, K; Ishibashi, S; Nagashima, S; Okada, K; Saito, N; Takahashi, M; Wakabayashi, T | 1 |
| Cui, L; Hao, Z; Li, G; Sun, Y; Yan, D | 1 |
| Chatsudthipong, V; Kongkaew, A; Lungkaphin, A; Thongnak, L | 1 |
| Flatt, PR; Irwin, N; Moffett, RC; Tanday, N | 1 |
| Bi, Q; Gu, W; Liang, L; Meng, F; Yang, M; Yang, X; Yu, J; Zeng, L; Zhang, T | 1 |
| Bashllari, R; Cimino, F; Cristani, M; Molonia, MS; Muscarà, C; Occhiuto, C; Saija, A; Speciale, A; Villarroya, F | 1 |
| Bi, K; He, B; Jia, Y; Li, F; Nian, T; Wang, Z; Yan, T | 1 |
| Bellalah, A; Bouhajeb, R; Chekir-Ghedira, L; Dhaouefi, Z; Khlifi, R; Lahmar, A; Sioud, F; Toumia, IB | 1 |
| Aguilar-Ballester, M; Burks, DJ; González-Navarro, H; Herrero-Cervera, A; Martínez-Hervás, S; Real, JT; Taberner-Cortés, A; Vinué, Á | 1 |
| Haluzik, M; Huttl, M; Kucera, J; Malinska, H; Markova, I; Miklankova, D; Oliyarnyk, O; Sedlacek, R; Trnovska, J | 1 |
| Bian, F; Chen, L; Hao, X; Lei, P; Lu, W; Ma, W; Wang, Q; Zhang, L; Zhang, Y; Zhao, Y; Zheng, T | 1 |
| Chrysafi, P; Feigh, M; Mantzoros, CS; Perakakis, N; Veidal, SS | 1 |
| Imai, J; Katagiri, H; Kawana, Y; Sawada, S; Yamada, T | 1 |
| Jin, X; Ong, M; Peng, J; Qu, X | 1 |
| Chu, L; Guan, S; Liu, H; Ma, Z; Wang, W; Yi, J | 1 |
| Hyun, CK; Kim, B; Kim, MS | 1 |
| Chen, G; Kaneko, S; Mayoux, E; Nagashimada, M; Nagata, N; Ni, Y; Ota, T; Xu, L; Zhuge, F | 1 |
| Chattipakorn, N; Chattipakorn, SC; Jaiwongkam, T; Kerdphoo, S; Pratchayasakul, W; Sa-Nguanmoo, P; Tanajak, P | 1 |
| Adrio, B; Agra, RM; Díaz-Rodríguez, E; Eiras, S; Fernández, ÁL; García-Caballero, T; González-Juanatey, JR | 1 |
| Baek, SI; Choi, SH; Jang, HC; Kim, KM; Lee, DH; Lim, S; Min, SH; Moon, JH; Oh, TJ; Park, KS | 1 |
| Hattori, S | 1 |
| Levi, M; Luo, Y; Myakala, K; Orlicky, DJ; Wang, D; Wang, X; Yang, P | 1 |
| Brandjes, DPM; Gerards, MC; Gerdes, VEA; Hageman, IMG; Hoekstra, JBL; Kross, M; Patberg, KW; Potter van Loon, BJ; Snijders, D; Venema, GE; Vriesendorp, TM | 1 |
| Matsuba, I; Matsuba, R; Nagai, Y; Shimokawa, M; Tanaka, Y | 1 |
| Gunji, R; Kaku, K; Senda, M; Tamura, M; Terauchi, Y | 1 |
| Abdul-Ghani, M; Adams, J; Al Jobori, H; Cersosimo, E; Daniele, G; DeFronzo, RA; Solis-Herrera, C; Triplitt, C | 1 |
| Chatsudthipong, V; Chattipakorn, N; Chueakula, N; Jaikumkao, K; Lungkaphin, A; Pongchaidecha, A; Thongnak, L; Wanchai, K | 1 |
| Abassi, Z; Hollander, K; Landa, N; Leor, J; Naftali-Shani, N; Rath, L; Rosenthal, T; Younis, F | 1 |
| Akiyama, N; Kashiwagi, A; Kazuta, K; Kosakai, Y; Nakamura, I; Sakatani, T; Takahashi, H; Ueyama, E | 1 |
| Chen, C; Hao, J; Huang, H; Huang, K; Liang, Y; Wang, Y; Zhang, X | 1 |
| Ebenbichler, CF; Kempf, P; Laimer, M; Lunger, L; Mader, JK; Melmer, A; Pieber, TR; Stettler, C; Tilg, H | 1 |
| Bai, M; Cheng, YX; Li, YC; Qiao, JY; Shen, JD; Wang, BY | 1 |
| Li, HS | 1 |
| González-Ortiz, M; Martínez-Abundis, E; Ramírez-Rodríguez, AM | 1 |
| Guo, X; Li, D; Li, J; Li, S; Ren, G; Wang, N; Zhang, T | 1 |
| Olgar, Y; Turan, B | 1 |
| Akkus, E; Degirmenci, S; Durak, A; Olgar, Y; Tuncay, E; Turan, B | 1 |
| Lin, K; Liu, H; Lu, A; Qi, X; Sun, Z; Yu, K; Zhang, M; Zhu, J | 1 |
| He, S; Meng, X; Sun, G; Sun, X; Wang, R; Ye, T; Zhang, C | 1 |
| Bell, C; Biela, LM; Grimm, NC; Luckasen, GJ; Melby, CL; Newman, AA; Schoenberg, HM; Trikha, SRJ; Wilburn, JR | 1 |
| Aso, Y; Iijima, T; Jojima, T; Kato, K; Kishi, H; Maejima, Y; Sakurai, S; Shimizu, M; Shimomura, K; Usui, I | 1 |
| Abe, T; Fujihara, K; Ishizawa, M; Kaku, K; Matsubayashi, Y; Nojima, T; Sone, H; Suganami, H; Tanaka, S; Yoshida, A | 1 |
| Chandrasekaran, S; Chatham, L; Gonzalez de Mejia, E; Juvik, J; Kumar, D; Luna-Vital, D; Singh, V; Tao, T; Zhang, Q | 1 |
| Guo, L; Li, J; Li, L; Li, X; Liu, H; Liu, R; Luo, Y; Mou, H; Yang, G; Yang, M; Zhang, C; Zhang, X; Zhang, Y | 1 |
| Kitamura, K; Miyachi, Y; Mori, K; Nakamura, S; Ogawa, Y; Shiba, K; Tsuchiya, K | 1 |
| Ito, K; Kashiwagi, Y; Kimura, H; Nagoshi, T; Oi, Y; Tanaka, TD; Tanaka, Y; Yoshii, A; Yoshimura, M; Yoshino, T | 1 |
| Kang, W; Liu, Z; Saadeldeen, FSA; Wang, HD; Wei, J; Xu, L; Xu, X; Zhao, Y | 1 |
| Brownell, LA; Corneliusen, B; Jia, Q; Pantier, M; Yimam, M; Zhao, J | 1 |
| Hayashizaki, Y; Imamura, M; Kihara, R; Kobayashi, Y; Kurosaki, E; Li, Q; Noda, A; Sasamata, M; Shibasaki, M; Tahara, A; Takasu, T; Tomiyama, H; Yamajuku, D; Yokono, M | 1 |
| Chellan, N; Fey, SJ; Ghoor, S; Joubert, E; Louw, J; Muller, CJ; Pheiffer, C; Sanderson, M | 1 |
| Chi, R; Kong, P; Lu, Y; Wang, N; Zhang, L | 1 |
| Boden, G; Chalamandaris, AG; Duchesne, D; Henry, RR; Iqbal, N; List, J; Mudaliar, S; Smith, S | 1 |
| García, SD; Sanz, AD; Sanz, SD | 1 |
| Ma, LY; Wu, XY; Yu, RQ; Zhou, X; Zhu, J | 1 |
| Guo, Y; Kong, P; Lin, D; Lu, Y; Zhang, L | 1 |
| Bouwens, L; Chellan, N; Cnop, M; Da Cunha, DA; Himpe, E; Joubert, E; Ladriere, L; Louw, J; Mathijs, I; Muller, C; Roux, CR | 1 |
| Beg, M; Gaikwad, AN; Sashidhara, KV; Singh, SP; Varshney, S | 1 |
| Christensen, M; Gluud, LL; Knop, FK; Storgaard, H; Vilsbøll, T | 1 |
| Chen, C; Hao, J; Huang, H; Huang, J; Huang, K; Li, J; Liu, P | 1 |
| Katakami, N; Matsuoka, TA; Shimomura, I; Shiraiwa, T; Takahara, M | 1 |
| Tan, Y; Yao, F; Zhang, N; Zhang, Q | 1 |
| Camps, J; García-Heredia, A; Geeraert, B; Holvoet, P; Joven, J; López-Sanromà, S; Rull, A | 1 |
| Bai, X; Bian, F; Chen, X; Chi, J; Jin, S; Li, W; Wu, D; Wu, G; Xing, S; Yang, X; Zhang, Y; Zheng, T | 1 |
| Abderrahmani, A; Beaucamps, C; Bonner, C; Delalleau, N; Deprez, B; Gmyr, V; Kerr-Conte, J; Malaisse, WJ; Moerman, E; Pattou, F; Popescu, I; Queniat, G; Sener, A; Staels, B; Thévenet, J | 1 |
| Jia, Y; Lee, JH; Lee, SJ; Seo, WD; Wu, C | 1 |
| Scheen, AJ | 1 |
| Fukazawa, M; Ikeda, S; Iwamoto, M; Iwayama, K; Kadowaki, T; Katsuyama, H; Kubota, N; Kubota, T; Obata, A; Sakurai, Y; Sato, H; Suzuki, Y; Takamoto, I; Tokuyama, K; Ueki, K | 1 |
| Fujita, K; Honda, Y; Imajo, K; Kato, S; Kato, T; Kessoku, T; Mawatari, H; Nakajima, A; Ogawa, Y; Saito, S; Tomeno, W; Yoneda, M | 1 |
| Abdul-Ghani, M; Daniele, G; DeFronzo, RA; Mari, A; Merovci, A; Solis-Herrera, C; Tripathy, D; Xiong, J | 1 |
| Blüher, M; Kern, M; Klein, T; Klöting, N; Mark, M; Mayoux, E | 1 |
| Fujisawa, Y; Kittikulsuth, W; Kohno, M; Masaki, T; Mori, H; Nakano, D; Nishiyama, A; Ogata, H; Ohmori, K; Rahman, A; Takeshige, Y | 1 |
| Chen, C; Huang, H; Huang, J; Li, J; Liu, P; Wang, Y; Ye, J | 1 |
| Furuke, S; Kanno, K; Komiya, C; Miyachi, Y; Ogawa, Y; Shiba, K; Shimazu, N; Tsuchiya, K; Yamaguchi, S | 1 |
| Aihara, Y; Asada, K; Douhara, A; Kawaratani, H; Kitade, M; Moriya, K; Namisaki, T; Nishimura, N; Noguchi, R; Okura, Y; Takeda, K; Yoshiji, H | 1 |
| Abiru, N; Ando, T; Horie, I; Kawakami, A; Shigeno, R | 1 |
| Abiko, A; Atageldiyeva, K; Fujita, Y; Haneda, M; Honjo, J; Makino, Y; Mizumoto, K; Takeda, Y; Takiyama, Y; Yanagimachi, T | 1 |
| Abdul-Ghani, M; Daniele, G; DeFronzo, RA; Eldor, R; Merovci, A; Norton, L; Solis-Herrera, C; Tripathy, D; Xiong, J | 1 |
| Kaku, K; Kaneto, H; Kimura, T; Matsuoka, TA; Obata, A; Okauchi, S; Shimo, N; Shimoda, M | 1 |
| Hirate, M; Kutoh, E; Murayama, T; Wada, A | 1 |
| Li, SZ; Sun, LL; Xu, JJ; Zhang, L; Zhang, Y | 1 |
| Choi, SH; Han, JH; Jang, HC; Kim, KM; Kim, YB; Lee, DH; Lee, G; Lee, HS; Lim, S; Maeng, HJ; Oh, TJ; Park, KS | 1 |
| Chan, SP; Lim, LL; Moses, K; Rajadhyaksha, V; Tan, AT | 1 |
| González-Ortiz, M; Martínez-Abundis, E; Méndez-Del Villar, M; Ramírez-Rodríguez, AM | 1 |
| Cimino, F; Ferrari, D; Fratantonio, D; Molonia, MS; Saija, A; Speciale, A; Virgili, F | 1 |
| Ho, CT; Huang, MT; Li, S; Liu, Y; Pan, MH; Tang, W; Wu, JC | 1 |
| Bramlage, P; Friedrich, S; Jumar, A; Karg, MV; Ott, C; Schmieder, RE; Striepe, K | 1 |
| Andrikopoulos, S; Joannides, CN; Lamont, BJ; Mangiafico, SP; Waters, MF | 1 |
| Chu, L; Gao, Y; Li, J; Liu, H; Ma, Z; Wang, W; Yao, W; Yi, J | 1 |
| Fujikura, H; Fujimori, Y; Isaji, M; Ishikawa-Takemura, Y; Katsuno, K; Nakashima, I | 1 |
| Lv, JH; Pan, JQ; Zheng, LY | 1 |
| Grace, MH; Kuhn, P; Lila, MA; Logendra, S; Poulev, A; Raskin, I; Ribnicky, DM; Yousef, GG | 1 |
| Jiang, B; Lu, Y; Qiao, J; Yang, Y | 1 |
| Benhabilès, N; Crombé, F; Geeraert, B; Geuns, JM; Holvoet, P; Hulsmans, M | 1 |
| Guo, H; Ling, W; Xia, M; Zhang, W; Zhong, R; Zou, T | 1 |
| Li, L; Long, CL; Niu, HM; Shi, YN; Sun, L; Tang, GH; Wang, HS; Wang, YH; Zhao, FW | 1 |
| Guo, C; Han, B; Ma, Q; Pan, C; Song, H; Wang, Z; Xue, L; Zhao, S | 1 |
| Li, J; Liang, J; Ma, S; Wang, H; Wu, F | 1 |
| Grasso, P; Leinung, MC | 1 |
| Chen, LH; Leung, PS | 1 |
| Aoki, H; Horio, F; Osawa, T; Tsuda, T; Uchida, K | 1 |
| Henriksen, EJ; Lailerd, N; Saengsirisuwan, V; Sloniger, JA; Toskulkao, C | 1 |
| Arakawa, K; Fujita, T; Ishihara, T; Matsumoto, Y; Nawano, M; Oku, A; Saito, A; Ueta, K | 1 |
| Abudula, R; Chen, J; Colombo, M; Dyrskog, SE; Hermansen, K; Jeppesen, PB | 1 |
| Chang, JC; Cheng, JT; Liu, IM; Wu, MC | 1 |
| Ashida, H; Fukuda, I; Horio, F; Hoshino, H; Ichi, T; Isa, Y; Kadowaki, M; Nishimura, N; Nishiumi, S; Sasaki, R; Tanaka, A; Tsuda, T | 1 |
| Guo, H; Hu, Y; Ling, W; Liu, C; Wang, Q; Xia, M | 1 |
| Anai, M; Arakawa, K; Asano, T; Ishirahara, T; Kikuchi, M; Nawano, M; Oku, A; Saito, A; Ueta, K; Umebayashi, I | 1 |
| Adachi, T; Arakawa, K; Ikezawa, K; Kano-Ishihara, T; Matsumoto, T; Oku, A; Saito, A; Tsuda, K; Ueta, K; Yasuda, K | 1 |
| Hashimoto, I; Ichiki, H; Ishida, T; Ishihara, E; Iwamoto, N; Kato, M; Komatsu, Y; Kubo, M; Miura, T; Okada, M; Tanigawa, K | 1 |
8 review(s) available for glucose, (beta-d)-isomer and Insulin Resistance
| Article | Year |
|---|---|
Efficacy and Safety of Empagliflozin on Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis.
Topics: Benzhydryl Compounds; Glucosides; Humans; Insulin Resistance; Non-alcoholic Fatty Liver Disease | 2022 |
Chinese Herbal Medicine for the Optimal Management of Polycystic Ovary Syndrome.
Topics: Androgens; Berberine; Drugs, Chinese Herbal; Female; Ginsenosides; Glucosides; Humans; Insulin Resistance; Monoterpenes; Phenanthrenes; Phytotherapy; Polycystic Ovary Syndrome; Resveratrol; Stilbenes; Theca Cells | 2017 |
[Type 2 diabetes mellitus and obesity: should we treat the obesity or the diabetes?].
Topics: Bariatric Surgery; Benzhydryl Compounds; Causality; Comorbidity; Diabetes Mellitus, Type 2; Diet, Diabetic; Diet, Reducing; Disease Management; Evidence-Based Medicine; Exercise Therapy; Glucagon-Like Peptide 1; Glucosides; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Metabolic Syndrome; Obesity; Practice Guidelines as Topic; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Weight Loss | 2013 |
The effects of sodium-glucose co-transporter 2 inhibitors in patients with type 2 diabetes: protocol for a systematic review with meta-analysis of randomised trials.
Topics: Benzhydryl Compounds; Blood Glucose; Blood Pressure; Body Mass Index; Body Weight; Canagliflozin; Diabetes Mellitus, Type 2; Glucosides; Glycated Hemoglobin; Humans; Insulin Resistance; Randomized Controlled Trials as Topic; Renal Elimination; Sodium-Glucose Transporter 2 Inhibitors; Systematic Reviews as Topic; Thiophenes; Treatment Outcome | 2014 |
SGLT2 inhibition: efficacy and safety in type 2 diabetes treatment.
Topics: Aged; Benzhydryl Compounds; Blood Glucose; Canagliflozin; Diabetes Mellitus, Type 2; Glucose; Glucosides; Humans; Hypoglycemic Agents; Insulin Resistance; Randomized Controlled Trials as Topic; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2015 |
Beneficial effects of sodium-glucose cotransporter 2 inhibitors for preservation of pancreatic β-cell function and reduction of insulin resistance.
Topics: Benzhydryl Compounds; Canagliflozin; Diabetes Mellitus, Type 2; Glucosides; Humans; Hypoglycemic Agents; Insulin Resistance; Insulin-Secreting Cells; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2017 |
Place of sodium-glucose cotransporter-2 inhibitors in East Asian subjects with type 2 diabetes mellitus: Insights into the management of Asian phenotype.
Topics: Asian People; Benzhydryl Compounds; Canagliflozin; Diabetes Complications; Diabetes Mellitus, Type 2; Evidence-Based Medicine; Glucosides; Humans; Hypoglycemic Agents; Insulin Resistance; Membrane Transport Modulators; Middle Aged; Reproducibility of Results; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2017 |
Inhibition of the sodium glucose co-transporter-2: its beneficial action and potential combination therapy for type 2 diabetes mellitus.
Topics: Animals; Benzhydryl Compounds; Body Weight; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Glucosides; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Inflammation; Insulin Resistance; Kidney; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2013 |
18 trial(s) available for glucose, (beta-d)-isomer and Insulin Resistance
| Article | Year |
|---|---|
Empagliflozin Improves Insulin Sensitivity of the Hypothalamus in Humans With Prediabetes: A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Trial.
Topics: Aged; Benzhydryl Compounds; Diabetes Mellitus, Type 2; Double-Blind Method; Glucosides; Humans; Hypothalamus; Insulin Resistance; Middle Aged; Prediabetic State | 2022 |
The sodium-glucose cotransporter 2 inhibitor ipragliflozin improves liver function and insulin resistance in Japanese patients with type 2 diabetes.
Topics: Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucosides; Humans; Insulin; Insulin Resistance; Japan; Liver; Male; Middle Aged; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Time Factors; Treatment Outcome | 2022 |
Empagliflozin decreases remnant-like particle cholesterol in type 2 diabetes patients with insulin resistance.
Topics: Adult; Aged; Benzhydryl Compounds; Blood Glucose; Cholesterol; Diabetes Mellitus, Type 2; Female; Glucosides; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Lipoproteins; Male; Middle Aged; Prospective Studies; Triglycerides | 2018 |
Dapagliflozin for prednisone-induced hyperglycaemia in acute exacerbation of chronic obstructive pulmonary disease.
Topics: Aged; Benzhydryl Compounds; Combined Modality Therapy; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Glucocorticoids; Glucose; Glucosides; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Length of Stay; Male; Middle Aged; Monitoring, Ambulatory; Prednisone; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Sodium-Glucose Transporter 2 Inhibitors; Subcutaneous Tissue | 2018 |
Tofogliflozin decreases body fat mass and improves peripheral insulin resistance.
Topics: Adiposity; Anti-Obesity Agents; Benzhydryl Compounds; Biomarkers; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Electric Impedance; Glucose Clamp Technique; Glucosides; Glycated Hemoglobin; Hyperglycemia; Hypoglycemia; Insulin Resistance; Overweight; Sodium-Glucose Transporter 2 Inhibitors; Weight Loss | 2018 |
Long-term safety and efficacy of tofogliflozin as add-on to insulin in patients with type 2 diabetes: Results from a 52-week, multicentre, randomized, double-blind, open-label extension, Phase 4 study in Japan (J-STEP/INS).
Topics: Adult; Aged; Benzhydryl Compounds; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Follow-Up Studies; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Incidence; Insulin; Insulin Resistance; Japan; Male; Middle Aged; Risk; Sodium-Glucose Transporter 2 Inhibitors; Young Adult | 2018 |
Empagliflozin Treatment Is Associated With Improved β-Cell Function in Type 2 Diabetes Mellitus.
Topics: Adult; Benzhydryl Compounds; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Glucosides; Glycosuria; Humans; Hypoglycemic Agents; Insulin Resistance; Insulin-Secreting Cells; Male; Middle Aged | 2018 |
Improved cardiometabolic risk factors in Japanese patients with type 2 diabetes treated with ipragliflozin: a pooled analysis of six randomized, placebo-controlled trials.
Topics: Aged; Blood Glucose; Body Mass Index; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucosides; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Japan; Male; Middle Aged; Risk Factors; Thiophenes; Treatment Outcome | 2018 |
Short-term effects of dapagliflozin on insulin sensitivity, postprandial glucose excursion and ketogenesis in type 1 diabetes mellitus: A randomized, placebo-controlled, double blind, cross-over pilot study.
Topics: Adult; Benzhydryl Compounds; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Double-Blind Method; Drug Administration Schedule; Glucosides; Humans; Insulin Resistance; Ketone Bodies; Male; Middle Aged; Pilot Projects; Postprandial Period | 2018 |
Effect of Dapagliflozin on Insulin Secretion and Insulin Sensitivity in Patients with Prediabetes.
Topics: Adult; Benzhydryl Compounds; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucosides; Humans; Insulin; Insulin Resistance; Insulin Secretion; Male; Middle Aged; Placebos; Prediabetic State; Treatment Outcome | 2020 |
Influence of Sodium Glucose Cotransporter 2 Inhibition on Physiological Adaptation to Endurance Exercise Training.
Topics: Adaptation, Physiological; Adolescent; Adult; Benzhydryl Compounds; Blood Glucose; Combined Modality Therapy; Diabetes Mellitus, Type 2; Double-Blind Method; Endurance Training; Exercise Therapy; Female; Glucosides; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Physical Endurance; Sedentary Behavior; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Treatment Outcome; Young Adult | 2019 |
Impact of dapagliflozin, an SGLT2 inhibitor, on serum levels of soluble dipeptidyl peptidase-4 in patients with type 2 diabetes and non-alcoholic fatty liver disease.
Topics: Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Female; gamma-Glutamyltransferase; Glucosides; Hepatitis; Humans; Inflammation; Insulin Resistance; Intra-Abdominal Fat; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Sodium-Glucose Transporter 2 Inhibitors; Subcutaneous Fat; Weight Loss | 2019 |
Attenuation of Weight Loss Through Improved Antilipolytic Effect in Adipose Tissue Via the SGLT2 Inhibitor Tofogliflozin.
Topics: Adipose Tissue; Benzhydryl Compounds; Biomarkers; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Follow-Up Studies; Glucosides; Glycated Hemoglobin; Humans; Insulin Resistance; Lipolysis; Male; Middle Aged; Prognosis; Prospective Studies; Sodium-Glucose Transporter 2 Inhibitors; Weight Loss | 2019 |
Changes in insulin sensitivity and insulin secretion with the sodium glucose cotransporter 2 inhibitor dapagliflozin.
Topics: Adult; Aged; Benzhydryl Compounds; Blood Glucose; C-Peptide; Creatinine; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Glucose Tolerance Test; Glucosides; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Male; Metformin; Middle Aged; Sodium-Glucose Transporter 2 Inhibitors; Treatment Outcome | 2014 |
Effect of Dapagliflozin With and Without Acipimox on Insulin Sensitivity and Insulin Secretion in T2DM Males.
Topics: Adult; Aged; Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus, Type 2; Glucose Clamp Technique; Glucose Tolerance Test; Glucosides; Humans; Hypolipidemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Middle Aged; Pyrazines; Young Adult | 2016 |
Dapagliflozin Enhances Fat Oxidation and Ketone Production in Patients With Type 2 Diabetes.
Topics: Adolescent; Adult; Aged; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Creatinine; Diabetes Mellitus, Type 2; Double-Blind Method; Enzyme Inhibitors; Glucagon; Glucosides; Humans; Insulin; Insulin Resistance; Ketones; Lipid Metabolism; Middle Aged; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Young Adult | 2016 |
Effect of dapagliflozin administration on metabolic syndrome, insulin sensitivity, and insulin secretion.
Topics: Adult; Benzhydryl Compounds; Blood Glucose; Double-Blind Method; Female; Glucosides; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Lipids; Male; Metabolic Syndrome; Middle Aged; Weight Loss | 2018 |
A randomised study of the impact of the SGLT2 inhibitor dapagliflozin on microvascular and macrovascular circulation.
Topics: Aged; Benzhydryl Compounds; Blood Glucose; Blood Pressure; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucosides; Humans; Insulin Resistance; Laser-Doppler Flowmetry; Male; Microcirculation; Microvessels; Middle Aged; Prospective Studies; Sodium-Glucose Transporter 2 Inhibitors | 2017 |
117 other study(ies) available for glucose, (beta-d)-isomer and Insulin Resistance
| Article | Year |
|---|---|
Alpha lipoic acid and metformin alleviates experimentally induced insulin resistance and cognitive deficit by modulation of TLR2 signalling.
Topics: Animals; Anti-Inflammatory Agents; Cognition Disorders; Disease Models, Animal; Insulin; Insulin Resistance; Interleukin-6; Lipid Peroxidation; Lipids; Male; Maze Learning; Memory; Metformin; Mice; Signal Transduction; Thioctic Acid; Toll-Like Receptor 2; Zymosan | 2019 |
Insulin resistance induced by zymosan as a new animal model in mice.
Topics: Animals; Diabetes Mellitus, Experimental; Diet; Disease Models, Animal; Fructose; Insulin Resistance; Male; Mice; Mice, Inbred BALB C; Prediabetic State; Recovery of Function; Zymosan | 2013 |
Tumor necrosis factor mediates zymosan-induced increase in glucose flux and insulin resistance.
Topics: Absorption; Animals; Antibodies; Blood; Glucose; Hemodynamics; Hormones; Insulin; Insulin Resistance; Liver; Male; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Zymosan | 1995 |
Chebulagic acid attenuates HFD/streptozotocin induced impaired glucose metabolism and insulin resistance via up regulations of PPAR γ and GLUT 4 in type 2 diabetic rats.
Topics: Animals; Benzopyrans; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Glucosides; Hypoglycemic Agents; Insulin; Insulin Resistance; Liver; PPAR gamma; Rats; Rats, Wistar; Streptozocin | 2022 |
Sodium glucose cotransporter 2 inhibitor dapagliflozin depressed adiposity and ameliorated hepatic steatosis in high-fat diet induced obese mice.
Topics: Adiposity; Animals; Benzhydryl Compounds; Diabetes Mellitus, Type 2; Diet, High-Fat; Glucosides; Insulin Resistance; Mice; Mice, Inbred C57BL; Mice, Obese; Non-alcoholic Fatty Liver Disease; Obesity; Sodium-Glucose Transporter 2 Inhibitors | 2021 |
Use of a Sodium-Glucose Cotransporter 2 Inhibitor, Empagliflozin, in a Patient with Rabson-Mendenhall Syndrome.
Topics: Antigens, CD; Benzhydryl Compounds; Child; Donohue Syndrome; Glucosides; Humans; Insulin Resistance; Male; Mutation; Receptor, Insulin; Sodium-Glucose Transporter 2 Inhibitors | 2021 |
Complex Positive Effects of SGLT-2 Inhibitor Empagliflozin in the Liver, Kidney and Adipose Tissue of Hereditary Hypertriglyceridemic Rats: Possible Contribution of Attenuation of Cell Senescence and Oxidative Stress.
Topics: 3T3-L1 Cells; Adipose Tissue; Administration, Oral; Animals; Benzhydryl Compounds; Cell Survival; Cellular Senescence; Disease Models, Animal; Down-Regulation; Dyslipidemias; Gluconeogenesis; Glucosides; Hep G2 Cells; Humans; Hypertriglyceridemia; Hypoglycemic Agents; Insulin Resistance; Kidney; Lipogenesis; Liver; Male; Mice; Oxidative Stress; Rats; Sodium-Glucose Transporter 2 Inhibitors; Treatment Outcome; Up-Regulation; Weight Gain | 2021 |
Anthocyanins from
Topics: Anthocyanins; Diabetes Mellitus, Type 2; Elaeocarpaceae; Fatty Liver; Glucosides; Hep G2 Cells; Hepatocytes; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipid Metabolism; Lipids; Liver; Muscle Fibers, Skeletal; Muscle, Skeletal; Obesity; Olanzapine; Plant Extracts; Polyphenols | 2021 |
Orientin Improves Substrate Utilization and the Expression of Major Genes Involved in Insulin Signaling and Energy Regulation in Cultured Insulin-Resistant Liver Cells.
Topics: Aspalathus; Cell Line; Chalcones; Diabetes Mellitus, Type 2; Flavonoids; Gene Expression; Glucose; Glucosides; Hepatocytes; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Liver; Phosphatidylinositol 3-Kinases; Plant Extracts; Signal Transduction; Transcriptome | 2021 |
Evaluation of therapeutic effect of Premna herbacea in diabetic rat and isoverbascoside against insulin resistance in L6 muscle cells through bioenergetics and stimulation of JNK and AKT/mTOR signaling cascade.
Topics: Animals; Diabetes Mellitus, Type 2; Energy Metabolism; Glucose; Glucosides; Insulin; Insulin Resistance; Male; Molecular Docking Simulation; Muscle Cells; Phenols; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; TOR Serine-Threonine Kinases | 2021 |
In a Prediabetic Model, Empagliflozin Improves Hepatic Lipid Metabolism Independently of Obesity and before Onset of Hyperglycemia.
Topics: Animals; Benzhydryl Compounds; Cytochrome P-450 Enzyme System; Disease Models, Animal; Disease Progression; Glucosides; Hyperglycemia; Hyperlipoproteinemia Type IV; Inflammation Mediators; Insulin Resistance; Lipid Metabolism; Liver; Male; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; Prediabetic State; Rats; Rats, Mutant Strains; Rats, Wistar; Sodium-Glucose Transporter 2 Inhibitors | 2021 |
Effect of Dapagliflozin and Magnesium Supplementation on Renal Magnesium Handling and Magnesium Homeostasis in Metabolic Syndrome.
Topics: Animals; Benzhydryl Compounds; Diet, Carbohydrate Loading; Dietary Supplements; Disease Models, Animal; Fructose; Glucosides; Homeostasis; Insulin Resistance; Kidney; Kidney Tubules; Magnesium; Magnesium Deficiency; Magnesium Sulfate; Metabolic Syndrome; Rats; Sodium-Glucose Transporter 2 Inhibitors; TRPM Cation Channels | 2021 |
Cyanidin-3-O-Glucoside Supplementation Ameliorates Metabolic Insulin Resistance via Restoration of Nitric Oxide-Mediated Endothelial Insulin Transport.
Topics: Animals; Anthocyanins; Dietary Supplements; Endothelial Cells; Glucosides; Insulin; Insulin Resistance; Mice; Nitric Oxide; Nitric Oxide Synthase Type III | 2022 |
Effects of dapagliflozin on peripheral sympathetic nerve activity in standard chow- and high-fat-fed rats after a glucose load.
Topics: Action Potentials; Administration, Intravenous; Animal Feed; Animals; Benzhydryl Compounds; Diet, High-Fat; Glucose; Glucosides; Hypoglycemic Agents; Insulin Resistance; Male; Rats, Wistar; Sciatic Nerve; Sodium-Glucose Transporter 2 Inhibitors; Sympathetic Nervous System; Time Factors | 2022 |
Dapagliflozin Improves Body Fat Patterning, and Hepatic and Pancreatic Fat in Patients With Type 2 Diabetes in North India.
Topics: Adipose Tissue; Benzhydryl Compounds; Blood Glucose; Body Fat Distribution; Diabetes Mellitus, Type 2; Glucosides; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Liver | 2022 |
Eight weeks of empagliflozin does not affect pancreatic fat content and insulin secretion in people with prediabetes.
Topics: Benzhydryl Compounds; Diabetes Mellitus, Type 2; Glucosides; Humans; Insulin; Insulin Resistance; Insulin Secretion; Prediabetic State | 2022 |
Combination Therapy With Semaglutide and Dapagliflozin as an Effective Approach for the Management of Type A Insulin Resistance Syndrome: A Case Report.
Topics: Benzhydryl Compounds; Diabetes Mellitus; Glucagon-Like Peptides; Glucosides; Humans; Insulin; Insulin Resistance | 2022 |
Renoprotective effect of empagliflozin in cafeteria diet-induced insulin resistance in rats: Modulation of HMGB-1/TLR-4/NF-κB axis.
Topics: Animals; Benzhydryl Compounds; Diet; Dyslipidemias; Glucosides; HMGB Proteins; Insulin; Insulin Resistance; NF-kappa B; Rats; Toll-Like Receptor 4 | 2022 |
Preferential effect of Montelukast on Dapagliflozin: Modulation of IRS-1/AKT/GLUT4 and ER stress response elements improves insulin sensitivity in soleus muscle of a type-2 diabetic rat model.
Topics: Acetates; Animals; Antioxidants; Benzhydryl Compounds; Blood Glucose; Cyclopropanes; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endoplasmic Reticulum; Endoribonucleases; Glucose Transporter Type 4; Glucosides; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Leukotriene Antagonists; Metformin; Muscle, Skeletal; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Quinolines; Rats; Response Elements; Streptozocin; Sulfides | 2022 |
Empagliflozin prohibits high-fructose diet-induced cardiac dysfunction in rats via attenuation of mitochondria-driven oxidative stress.
Topics: Animals; Benzhydryl Compounds; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet; Fibrosis; Fructose; Glucose; Glucosides; Heart Diseases; Insulin Resistance; Mitochondria; Oxidative Stress; Palmitates; Palmitic Acid; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2022 |
Polydatin prevents lipotoxicity-induced dysfunction in pancreatic β-cells by inhibiting endoplasmic reticulum stress and excessive autophagy.
Topics: Animals; Apoptosis; Autophagy; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endoplasmic Reticulum Stress; Fatty Acids, Nonesterified; Glucosides; Insulin Resistance; Insulin-Secreting Cells; Mice; Palmitates; Stilbenes; Tunicamycin | 2022 |
Metformin, pioglitazone, dapagliflozin and their combinations ameliorate manifestations associated with NAFLD in rats via anti-inflammatory, anti-fibrotic, anti-oxidant and anti-apoptotic mechanisms.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Benzhydryl Compounds; Biomarkers; Cholesterol; Cholic Acid; Diet, High-Fat; Fibrosis; Glucosides; Inflammation; Insulin Resistance; Liver; Metformin; Non-alcoholic Fatty Liver Disease; Pioglitazone; Rats | 2022 |
Empaglifozin mitigates NAFLD in high-fat-fed mice by alleviating insulin resistance, lipogenesis and ER stress.
Topics: Animals; Benzhydryl Compounds; Diet, High-Fat; Endoplasmic Reticulum Stress; Glucosides; Insulin Resistance; Lipogenesis; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Sodium-Glucose Transporter 2 Inhibitors | 2019 |
Effects and mechanisms of iridoid glycosides from Patrinia scabiosaefolia on improving insulin resistance in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Carbon-13 Magnetic Resonance Spectroscopy; Dose-Response Relationship, Drug; Glucose; Glucosides; Insulin; Insulin Resistance; Iridoid Glycosides; Mice; Patrinia; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Spectrometry, Mass, Electrospray Ionization | 2019 |
Empagliflozin reverses obesity and insulin resistance through fat browning and alternative macrophage activation in mice fed a high-fat diet.
Topics: Adipose Tissue, Brown; Animals; Benzhydryl Compounds; Diet, High-Fat; Fatty Liver; Glucosides; Insulin Resistance; Macrophage Activation; Male; Mice; Mice, Inbred C57BL; Obesity; Sodium-Glucose Transporter 2 Inhibitors; Weight Gain | 2019 |
Dapagliflozin not only improves hepatic injury and pancreatic endoplasmic reticulum stress, but also induces hepatic gluconeogenic enzymes expression in obese rats.
Topics: Animals; Benzhydryl Compounds; Blood Glucose; Diet, High-Fat; Endoplasmic Reticulum Stress; Gluconeogenesis; Glucosides; Glycosuria; Insulin Resistance; Liver; Male; Metformin; Obesity; Pancreas; Rats, Wistar; Sodium-Glucose Transporter 2 Inhibitors | 2019 |
Anti-insulin resistance effects of salidroside through mitochondrial quality control.
Topics: AMP-Activated Protein Kinases; Animals; Diabetes Mellitus; Glucose; Glucosides; Humans; Insulin; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mitochondria; Phenols; Reactive Oxygen Species; Sirtuin 1 | 2020 |
Inhibition of tumor necrosis factor-α enhanced the antifibrotic effect of empagliflozin in an animal model with renal insulin resistance.
Topics: Animals; Benzhydryl Compounds; Disease Models, Animal; Glucosides; Infliximab; Insulin Resistance; Kidney Diseases; Male; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2020 |
Lansoprazole enhances the antidiabetic effect of dapagliflozin in fortified diet-fed streptozotocin-treated diabetic rats.
Topics: Animals; Benzhydryl Compounds; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus, Experimental; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Food, Fortified; Glucose Transporter Type 2; Glucosides; Hypoglycemic Agents; Inflammation Mediators; Insulin Resistance; Lansoprazole; Male; Oxidative Stress; Pancreas; PPAR gamma; Random Allocation; Rats; Rats, Wistar; Sodium-Glucose Transporter 2 Inhibitors | 2020 |
Dapagliflozin restores insulin and growth hormone secretion in obese mice.
Topics: Animals; Benzhydryl Compounds; Body Composition; Diabetes Mellitus, Type 2; Energy Metabolism; Gene Expression; Glucosides; Growth Hormone; Humans; Insulin; Insulin Resistance; Insulin Secretion; Mice, Inbred C57BL; Mice, Knockout; Obesity; Sodium-Glucose Transporter 2 Inhibitors | 2020 |
Relation between HOMA-IR and insulin sensitivity index determined by hyperinsulinemic-euglycemic clamp analysis during treatment with a sodium-glucose cotransporter 2 inhibitor.
Topics: Adult; Aged; Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Glucosides; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Sodium-Glucose Transporter 2 Inhibitors | 2020 |
Long-term efficacy of the sodium-glucose cotransporter 2 inhibitor, ipragliflozin, in a case of type A insulin resistance syndrome.
Topics: Adult; Biomarkers; Blood Glucose; Diabetes Mellitus; Female; Glucosides; Glycated Hemoglobin; Humans; Insulin Resistance; Prognosis; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2020 |
Effects of Dapagliflozin and Sitagliptin on Insulin Resistant and Body Fat Distribution in Newly Diagnosed Type 2 Diabetic Patients.
Topics: Benzhydryl Compounds; Blood Glucose; Body Fat Distribution; Diabetes Mellitus, Type 2; Female; Glucosides; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Metformin; Middle Aged; Sitagliptin Phosphate; Treatment Outcome | 2020 |
Effects of dapagliflozin and statins attenuate renal injury and liver steatosis in high-fat/high-fructose diet-induced insulin resistant rats.
Topics: Acute Kidney Injury; Animals; Atorvastatin; Benzhydryl Compounds; Blotting, Western; Dietary Carbohydrates; Dietary Fats; Drug Therapy, Combination; Fatty Liver; Fructose; Glucosides; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin Resistance; Male; Rats; Rats, Wistar | 2020 |
Dapagliflozin exerts positive effects on beta cells, decreases glucagon and does not alter beta- to alpha-cell transdifferentiation in mouse models of diabetes and insulin resistance.
Topics: Animals; Benzhydryl Compounds; Blood Glucose; Body Weight; Cell Transdifferentiation; Diabetes Mellitus, Experimental; Diet, High-Fat; Energy Intake; Glucagon; Glucagon-Secreting Cells; Glucosides; Homeodomain Proteins; Hydrocortisone; Insulin; Insulin Resistance; Insulin-Secreting Cells; Islets of Langerhans; Male; Mice, Transgenic; Sodium-Glucose Transporter 2 Inhibitors; Streptozocin; Trans-Activators | 2020 |
Pharmacological and metagenomics evidence of polysaccharide from Polygonum multiflorum in the alleviation of insulin resistance.
Topics: AMP-Activated Protein Kinases; Animals; Fallopia multiflora; Fatty Acids, Volatile; Feces; Gastrointestinal Microbiome; Glucosides; Insulin; Insulin Resistance; Liver; Male; Metagenomics; Polysaccharides; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; RNA, Ribosomal, 16S; Signal Transduction; Stilbenes | 2020 |
Cyanidin-3-O-glucoside restores insulin signaling and reduces inflammation in hypertrophic adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Adiponectin; Animals; Anthocyanins; Fatty Acid-Binding Proteins; Glucose Transporter Type 1; Glucosides; Humans; Inflammation; Insulin Resistance; Mice; NF-kappa B; Palmitic Acid; PPAR gamma; Signal Transduction | 2020 |
Salidroside from Rhodiola wallichiana var. cholaensis reverses insulin resistance and stimulates the GLP-1 secretion by alleviating ROS-mediated activation of MAPKs signaling pathway and mitigating apoptosis.
Topics: Apoptosis; Glucagon-Like Peptide 1; Glucosides; Humans; Insulin Resistance; Mitogen-Activated Protein Kinase Kinases; Phenols; Reactive Oxygen Species; Rhodiola; Signal Transduction | 2020 |
Erica multiflora extract rich in quercetin-3-O-glucoside and kaempferol-3-O-glucoside alleviates high fat and fructose diet-induced fatty liver disease by modulating metabolic and inflammatory pathways in Wistar rats.
Topics: Animals; Diet, High-Fat; Dietary Fats; Ericales; Fatty Liver; Fructose; Glucosides; Inflammation; Insulin Resistance; Kaempferols; Liver; Male; Metabolic Syndrome; Methanol; Monosaccharides; Oxidative Stress; Plant Extracts; Quercetin; Rats; Rats, Wistar; Reactive Oxygen Species; Tandem Mass Spectrometry | 2020 |
Dapagliflozin Does Not Modulate Atherosclerosis in Mice with Insulin Resistance.
Topics: Animals; Atherosclerosis; Benzhydryl Compounds; Blood Glucose; Computational Biology; Disease Models, Animal; Fasting; Glucose; Glucosides; Immunohistochemistry; Insulin Resistance; Macrophages; Mice; Mice, Knockout, ApoE; Plaque, Atherosclerotic; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2020 |
Metabolic cardio- and reno-protective effects of empagliflozin in a prediabetic rat model.
Topics: Animals; Benzhydryl Compounds; Disease Models, Animal; Glucose; Glucosides; Heart; Insulin Resistance; Ketone Bodies; Kidney; Male; Oxidative Stress; Prediabetic State; Protective Agents; Rats; Rats, Wistar | 2020 |
Salidroside alleviates diabetic neuropathic pain through regulation of the AMPK-NLRP3 inflammasome axis.
Topics: AMP-Activated Protein Kinases; Analgesics; Animals; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Ganglia, Spinal; Glucosides; Hypoglycemic Agents; Inflammasomes; Insulin Resistance; Male; Neuralgia; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Pain Threshold; Phenols; Rats, Sprague-Dawley; Signal Transduction | 2021 |
Empagliflozin Improves Metabolic and Hepatic Outcomes in a Non-Diabetic Obese Biopsy-Proven Mouse Model of Advanced NASH.
Topics: Animals; Antigens, CD; Benzhydryl Compounds; Biopsy; Body Composition; Body Weight; Disease Models, Animal; Glucose; Glucosides; Homeostasis; Insulin Resistance; Lactosylceramides; Lipidomics; Liver; Mice, Inbred C57BL; Mice, Obese; Non-alcoholic Fatty Liver Disease; Triglycerides | 2021 |
Sodium-Glucose Cotransporter 2 Inhibitor Improves Complications of Lipodystrophy: A Case Report.
Topics: Adult; Diabetes Mellitus; Fatty Liver; Glucosides; Glycated Hemoglobin; Humans; Insulin Resistance; Lipodystrophy; Male; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2017 |
Paeoniflorin suppresses lipid accumulation and alleviates insulin resistance by regulating the Rho kinase/IRS-1 pathway in palmitate-induced HepG2Cells.
Topics: Cell Line, Tumor; Fatty Liver; Glucose; Glucosides; Glycogen Synthase Kinase 3 beta; Hep G2 Cells; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Lipid Metabolism; Lipids; Monoterpenes; Palmitates; Phosphorylation; Proto-Oncogene Proteins c-akt; rho-Associated Kinases; Signal Transduction | 2017 |
Syringin attenuates insulin resistance via adiponectin-mediated suppression of low-grade chronic inflammation and ER stress in high-fat diet-fed mice.
Topics: Adiponectin; Animals; Diet, High-Fat; Endoplasmic Reticulum Stress; Glucose Tolerance Test; Glucosides; Inflammation; Injections, Intraperitoneal; Insulin Resistance; Male; Mice; Mice, Obese; Phenylpropionates | 2017 |
SGLT2 Inhibition by Empagliflozin Promotes Fat Utilization and Browning and Attenuates Inflammation and Insulin Resistance by Polarizing M2 Macrophages in Diet-induced Obese Mice.
Topics: Adipose Tissue; Adiposity; Animals; Benzhydryl Compounds; Biomarkers; Body Weight; Diet, High-Fat; Energy Metabolism; Fatty Acids; Fatty Liver; Glucose; Glucosides; Hypoglycemic Agents; Inflammation; Insulin Resistance; Macrophage Activation; Macrophages; Male; Mice; Muscle, Skeletal; Obesity; Oxidation-Reduction; Sodium-Glucose Transporter 2 Inhibitors | 2017 |
SGLT2-inhibitor and DPP-4 inhibitor improve brain function via attenuating mitochondrial dysfunction, insulin resistance, inflammation, and apoptosis in HFD-induced obese rats.
Topics: Adamantane; Animals; Anti-Inflammatory Agents; Apoptosis; Benzhydryl Compounds; Brain; Cognition Disorders; Diet, High-Fat; Dipeptidyl-Peptidase IV Inhibitors; Glucosides; Insulin; Insulin Resistance; Long-Term Potentiation; Male; Malondialdehyde; Maze Learning; Membrane Potential, Mitochondrial; Memory; Mitochondria; Neuroprotective Agents; Nitriles; Obesity; Oxidative Stress; Pyrrolidines; Rats, Wistar; Reactive Oxygen Species; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Vildagliptin | 2017 |
Effects of dapagliflozin on human epicardial adipose tissue: modulation of insulin resistance, inflammatory chemokine production, and differentiation ability.
Topics: Adipogenesis; Adipokines; Adipose Tissue, White; Benzhydryl Compounds; Chemokines; Endothelial Cells; Glucose; Glucosides; Humans; Inflammation Mediators; Insulin; Insulin Resistance; Paracrine Communication; Pericardium; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Subcutaneous Fat | 2018 |
Degree of ketonaemia and its association with insulin resistance after dapagliflozin treatment in type 2 diabetes.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Aged; Benzhydryl Compounds; Case-Control Studies; Diabetes Mellitus, Type 2; Glucosides; Humans; Hypoglycemic Agents; Insulin Resistance; Ketosis; Middle Aged; Young Adult | 2018 |
The Sodium-Glucose Cotransporter 2 Inhibitor Dapagliflozin Prevents Renal and Liver Disease in Western Diet Induced Obesity Mice.
Topics: Animals; Benzhydryl Compounds; Blood Glucose; Diet, Western; Glucosides; Inflammation; Insulin Resistance; Kidney Diseases; Kidney Glomerulus; Lipids; Liver; Liver Cirrhosis; Liver Diseases; Male; Mice, Inbred C57BL; Mice, Obese; Obesity; Oxidative Stress; Sodium-Glucose Transporter 2 Inhibitors; Weight Gain | 2018 |
Renal outcomes with sodium glucose cotransporter 2 (SGLT2) inhibitor, dapagliflozin, in obese insulin-resistant model.
Topics: Animals; Benzhydryl Compounds; Diet, High-Fat; Disease Models, Animal; Glucosides; Humans; Insulin; Insulin Resistance; Kidney; Kidney Diseases; Male; Metformin; Obesity; Organic Anion Transporters, Sodium-Independent; Oxidative Stress; Rats; Rats, Wistar; Signal Transduction; Sodium-Glucose Transporter 2 | 2018 |
Beneficial Effect of the SGLT2 Inhibitor Empagliflozin on Glucose Homeostasis and Cardiovascular Parameters in the Cohen Rosenthal Diabetic Hypertensive (CRDH) Rat.
Topics: Animals; Benzhydryl Compounds; Biomarkers; Blood Glucose; Blood Pressure; Diabetes Mellitus; Disease Models, Animal; Glucosides; Homeostasis; Hypertension; Hypertrophy, Left Ventricular; Insulin Resistance; Kidney; Male; Pancreas; Proteinuria; Rats, Inbred SHR; Sodium-Glucose Transporter 2 Inhibitors; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2018 |
Polydatin Improves Glucose and Lipid Metabolisms in Insulin-Resistant HepG2 Cells through the AMPK Pathway.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Glucose; Glucosides; Glycogen Synthase Kinase 3 beta; Hep G2 Cells; Humans; Insulin Resistance; Lipid Metabolism; Proto-Oncogene Proteins c-akt; Receptors, LDL; Signal Transduction; Sterol Regulatory Element Binding Protein 1; Stilbenes | 2018 |
Paeoniflorin Ameliorates Fructose-Induced Insulin Resistance and Hepatic Steatosis by Activating LKB1/AMPK and AKT Pathways.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Biomarkers; Blood Glucose; Disease Models, Animal; Enzyme Activation; Fructose; Glucosides; Glycogen; Insulin; Insulin Resistance; Lipids; Lipogenesis; Liver; Male; Monoterpenes; Non-alcoholic Fatty Liver Disease; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction | 2018 |
Salidroside and Curcumin Formula Prevents Liver Injury in Nonalcoholic Fatty Liver Disease in Rats.
Topics: AMP-Activated Protein Kinases; Animals; Biomarkers; Blood Glucose; Curcumin; Diet, High-Fat; Disease Models, Animal; Drug Combinations; Glucosides; Insulin; Insulin Resistance; Lipid Metabolism; Lipid Peroxidation; Liver; Male; Non-alcoholic Fatty Liver Disease; Phenols; Rats, Sprague-Dawley; Signal Transduction | 2018 |
Fibroblast growth factor 21 regulates glucose metabolism in part by reducing renal glucose reabsorption.
Topics: Animals; Blood Glucose; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Fibroblast Growth Factors; Glucose; Glucosides; Homeostasis; Humans; Hyperglycemia; Insulin; Insulin Resistance; Kidney; Male; Mice; Mice, Inbred C57BL; PPAR delta; Sodium-Glucose Transporter 2 | 2018 |
A sodium-glucose cotransporter 2 (SGLT2) inhibitor dapagliflozin comparison with insulin shows important effects on Zn
Topics: Animals; Benzhydryl Compounds; Biological Transport; Endoplasmic Reticulum; Gene Expression Regulation; Glucosides; Insulin; Insulin Resistance; Male; Matrix Metalloproteinases; Metabolic Syndrome; Myocytes, Cardiac; Oxidative Stress; Proteolysis; Rats; Rats, Wistar; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Zinc | 2019 |
A SGLT2 inhibitor dapagliflozin suppresses prolonged ventricular-repolarization through augmentation of mitochondrial function in insulin-resistant metabolic syndrome rats.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Benzhydryl Compounds; Blood Glucose; Disease Models, Animal; Glucosides; Heart Rate; Heart Ventricles; Insulin; Insulin Resistance; Male; Membrane Potential, Mitochondrial; Metabolic Syndrome; Mitochondria, Heart; Myocytes, Cardiac; Potassium Channels, Voltage-Gated; Rats, Wistar; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Ventricular Function, Left; Voltage-Gated Sodium Channels | 2018 |
AMPK activation is involved in hypoglycemic and hypolipidemic activities of mogroside-rich extract from Siraitia grosvenorii (Swingle) fruits on high-fat diet/streptozotocin-induced diabetic mice.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Blood Glucose; Cucurbitaceae; Diabetes Mellitus, Type 2; Diet, High-Fat; Fruit; Gluconeogenesis; Glucosides; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Insulin Resistance; Liver; Male; Mice; Mice, Inbred C57BL; Plant Extracts; Protein Kinases; Streptozocin | 2019 |
Gastrodin Alleviates Cognitive Dysfunction and Depressive-Like Behaviors by Inhibiting ER Stress and NLRP3 Inflammasome Activation in db/db Mice.
Topics: Animals; Apoptosis; Behavior, Animal; Benzyl Alcohols; Blood Glucose; Body Weight; Cognitive Dysfunction; Depression; Dyslipidemias; Endoplasmic Reticulum Stress; Glucosides; Inflammasomes; Insulin Resistance; Male; Memory; Mice; Models, Biological; Neurons; Neuroprotective Agents; NLR Family, Pyrin Domain-Containing 3 Protein | 2018 |
Relationship of phenolic composition of selected purple maize (Zea mays L.) genotypes with their anti-inflammatory, anti-adipogenic and anti-diabetic potential.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Anthocyanins; Anti-Inflammatory Agents; Cell Differentiation; Genotype; Glucosides; Hypoglycemic Agents; Insulin Resistance; Mice; Phenols; Plant Extracts; Principal Component Analysis; RAW 264.7 Cells; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Zea mays | 2019 |
Circulating complement-1q tumor necrosis factor-α-related protein isoform 5 levels are low in type 2 diabetes patients and reduced by dapagliflozin.
Topics: Benzhydryl Compounds; Biomarkers; Case-Control Studies; Collagen; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glucosides; Humans; Insulin Resistance; Male; Middle Aged; Prognosis; Sodium-Glucose Transporter 2 Inhibitors | 2020 |
Ipragliflozin-induced adipose expansion inhibits cuff-induced vascular remodeling in mice.
Topics: Adipocytes; Adipogenesis; Adipose Tissue; Adiposity; Animals; Cells, Cultured; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Fibrosis; Glucosides; Inflammation Mediators; Insulin Resistance; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Obesity; Paracrine Communication; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Vascular Remodeling; Vascular System Injuries | 2019 |
Cardiac ischemia-reperfusion injury under insulin-resistant conditions: SGLT1 but not SGLT2 plays a compensatory protective role in diet-induced obesity.
Topics: Animals; Benzhydryl Compounds; Blood Glucose; Canagliflozin; Diet, High-Fat; Disease Models, Animal; Glucose Transporter Type 4; Glucosides; Insulin Resistance; Isolated Heart Preparation; Male; Mice, Inbred C57BL; Myocardial Reperfusion Injury; Myocytes, Cardiac; Obesity; Phlorhizin; Signal Transduction; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2019 |
The Mechanism of Phillyrin from the Leaves of
Topics: 3T3-L1 Cells; Adipocytes; Animals; Forsythia; Gene Expression Regulation; Glucose Transporter Type 4; Glucosides; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Plant Leaves; Proto-Oncogene Proteins c-akt | 2019 |
UP780, a chromone-enriched aloe composition improves insulin sensitivity.
Topics: 3T3-L1 Cells; Adiponectin; Aloe; Animals; Benzophenones; Blood Glucose; Chemistry, Pharmaceutical; Chromones; Diabetes Mellitus, Type 2; Diet, High-Fat; Glucosides; Humans; Insulin; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Phytotherapy; Plant Preparations; Polysaccharides; Tyrosine | 2013 |
Effects of SGLT2 selective inhibitor ipragliflozin on hyperglycemia, hyperlipidemia, hepatic steatosis, oxidative stress, inflammation, and obesity in type 2 diabetic mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Diet, High-Fat; Fatty Liver; Glucose Tolerance Test; Glucosides; Glycosuria; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; Inflammation; Insulin; Insulin Resistance; Insulin Secretion; Male; Mice; Obesity; Oxidative Stress; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2013 |
Z-2-(β-D-glucopyranosyloxy)-3-phenylpropenoic acid, an α-hydroxy acid from rooibos (Aspalathus linearis) with hypoglycemic activity.
Topics: Animals; Aspalathus; Blood Glucose; Cell Line; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Gene Expression Regulation; Glucose; Glucose Tolerance Test; Glucosides; Hypoglycemic Agents; Insulin Resistance; Liver; Male; Muscle, Skeletal; Obesity; Phenylpropionates; Rats; Rats, Wistar | 2013 |
Effects of paeoniflorin on tumor necrosis factor-α-induced insulin resistance and changes of adipokines in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipokines; Anilides; Animals; Benzoates; Bridged-Ring Compounds; Chemokine CCL2; Drugs, Chinese Herbal; Gene Expression; Glucose; Glucosides; Inflammation; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Interleukin-6; Mice; Monoterpenes; Obesity; Paeonia; Phosphorylation; PPAR gamma; Proto-Oncogene Proteins c-akt; Tumor Necrosis Factor-alpha | 2013 |
[Cyanidin-3-glucoside attenuates body weight gain, serum lipid concentrations and insulin resistance in high-fat diet-induced obese rats].
Topics: Animals; Anthocyanins; Blood Glucose; Diet, High-Fat; Glucosides; Insulin Resistance; Lipids; Male; Obesity; Rats; Rats, Sprague-Dawley; Weight Gain | 2014 |
Phillyrin, a natural lignan, attenuates tumor necrosis factor α-mediated insulin resistance and lipolytic acceleration in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Animals; Anti-Inflammatory Agents; Cell Survival; Glucose; Glucosides; I-kappa B Kinase; Insulin Resistance; Lignans; Lipolysis; Mice; Obesity; Tumor Necrosis Factor-alpha | 2014 |
Phenylpropenoic acid glucoside augments pancreatic beta cell mass in high-fat diet-fed mice and protects beta cells from ER stress-induced apoptosis.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Size; Cells, Cultured; Crosses, Genetic; Diabetes Mellitus, Type 2; Diet, High-Fat; Endoplasmic Reticulum Stress; Fructose; Glucosides; Hypoglycemic Agents; Insulin Resistance; Insulin-Secreting Cells; Lipotropic Agents; Male; Mice, Transgenic; Obesity; Phenylpropionates; Proto-Oncogene Proteins c-bcl-2; Rats, Wistar; RNA Interference; Up-Regulation | 2014 |
Poliothrysoside and its derivatives as novel insulin sensitizers potentially driving AMPK activation and inhibiting adipogenesis.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; AMP-Activated Protein Kinases; Animals; Benzoates; Dose-Response Relationship, Drug; Enzyme Activation; Glucosides; Hypoglycemic Agents; Insulin Resistance; Mice; Molecular Structure; Structure-Activity Relationship | 2014 |
Polydatin improves glucose and lipid metabolism in experimental diabetes through activating the Akt signaling pathway.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Glucokinase; Glucose; Glucose-6-Phosphatase; Glucosides; Hep G2 Cells; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipid Metabolism; Liver; Male; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptors, LDL; Signal Transduction; Sterol Regulatory Element Binding Protein 1; Stilbenes | 2014 |
Ameliorated pancreatic β cell dysfunction in type 2 diabetic patients treated with a sodium-glucose cotransporter 2 inhibitor ipragliflozin.
Topics: Adult; Algorithms; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucose Tolerance Test; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Japan; Male; Middle Aged; Pilot Projects; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2015 |
Polydatin supplementation ameliorates diet-induced development of insulin resistance and hepatic steatosis in rats.
Topics: Adiponectin; Animals; Body Weight; Diet; Dietary Supplements; Disease Models, Animal; Fatty Liver; Gene Expression; Glucose Tolerance Test; Glucosides; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Leptin; Liver; Male; Rats; Stilbenes | 2015 |
Stevia-derived compounds attenuate the toxic effects of ectopic lipid accumulation in the liver of obese mice: a transcriptomic and metabolomic study.
Topics: Amino Acids; Animals; Bile Acids and Salts; Disease Models, Animal; Diterpenes, Kaurane; Fatty Liver; Glucose; Glucosides; Glutathione; Insulin Resistance; Lipid Metabolism; Liver; Male; Metabolomics; Mice; Mice, Obese; Obesity; Oxidative Stress; Peroxisome Proliferator-Activated Receptors; Plant Preparations; Stevia; Transcriptome | 2015 |
Salidroside ameliorates insulin resistance through activation of a mitochondria-associated AMPK/PI3K/Akt/GSK3β pathway.
Topics: Adipose Tissue; AMP-Activated Protein Kinases; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Glucosides; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hepatocytes; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipid Metabolism; Liver; Male; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Oxygen Consumption; Pancreas; Phenols; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt | 2015 |
Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion.
Topics: Administration, Oral; Adult; Animals; Benzhydryl Compounds; Blood Glucose; Cell Separation; Female; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation; Gene Silencing; Glucagon; Glucagon-Secreting Cells; Gluconeogenesis; Glucosides; Hepatocyte Nuclear Factor 4; Humans; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; RNA, Small Interfering; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2 | 2015 |
Saponarin activates AMPK in a calcium-dependent manner and suppresses gluconeogenesis and increases glucose uptake via phosphorylation of CRTC2 and HDAC5.
Topics: AMP-Activated Protein Kinases; Apigenin; Benzimidazoles; Biphenyl Compounds; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Cyclic AMP Response Element-Binding Protein; Enzyme Activators; Forkhead Box Protein O1; Forkhead Transcription Factors; Gluconeogenesis; Glucose; Glucose Transporter Type 4; Glucosides; Hep G2 Cells; Histone Deacetylases; Humans; Insulin Resistance; Metformin; Naphthalimides; Phosphorylation; Pyrones; Thiophenes; Transcription Factors | 2015 |
Tofogliflozin Improves Insulin Resistance in Skeletal Muscle and Accelerates Lipolysis in Adipose Tissue in Male Mice.
Topics: Adipose Tissue; Adipose Tissue, White; Animals; Benzhydryl Compounds; Diet, High-Fat; Fatty Acids, Nonesterified; Gene Expression; Glucose; Glucose Clamp Technique; Glucosides; Hypoglycemic Agents; Insulin Resistance; Ketone Bodies; Lipase; Lipid Metabolism; Lipogenesis; Lipolysis; Liver; Male; Mice; Muscle, Skeletal; Sodium-Glucose Transporter 2 Inhibitors; Sterol Esterase; Weight Gain | 2016 |
The Selective SGLT2 Inhibitor Ipragliflozin Has a Therapeutic Effect on Nonalcoholic Steatohepatitis in Mice.
Topics: Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucosides; Hypoglycemic Agents; Insulin Resistance; Mice; Non-alcoholic Fatty Liver Disease; Obesity; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Treatment Outcome | 2016 |
The SGLT2 inhibitor empagliflozin improves insulin sensitivity in db/db mice both as monotherapy and in combination with linagliptin.
Topics: Animals; Benzhydryl Compounds; Female; Glucose; Glucosides; Glycosides; Hypoglycemic Agents; Insulin Resistance; Insulin-Secreting Cells; Linagliptin; Lipid Metabolism; Mice; Sodium-Glucose Transporter 2 Inhibitors | 2016 |
A sodium-glucose co-transporter 2 inhibitor empagliflozin prevents abnormality of circadian rhythm of blood pressure in salt-treated obese rats.
Topics: Animals; Benzhydryl Compounds; Blood Glucose; Blood Pressure; Circadian Rhythm; Glucose Tolerance Test; Glucosides; Homeostasis; Hypertension; Hypoglycemic Agents; Insulin Resistance; Obesity; Rats; Rats, Inbred OLETF; Sodium Chloride, Dietary; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2016 |
Polydatin ameliorates lipid and glucose metabolism in type 2 diabetes mellitus by downregulating proprotein convertase subtilisin/kexin type 9 (PCSK9).
Topics: Animals; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Down-Regulation; Drugs, Chinese Herbal; Female; Germinal Center Kinases; Glucosides; Hep G2 Cells; Hepatocytes; Humans; Hydrogen Bonding; Hypoglycemic Agents; Insulin Resistance; Lipid Metabolism; Lipids; Liver; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Palmitic Acid; Proprotein Convertase 9; Proprotein Convertases; Protein Binding; Protein Conformation; Protein Serine-Threonine Kinases; Receptors, LDL; RNA Interference; Serine Endopeptidases; Stilbenes; Time Factors; Transfection | 2016 |
Ipragliflozin Improves Hepatic Steatosis in Obese Mice and Liver Dysfunction in Type 2 Diabetic Patients Irrespective of Body Weight Reduction.
Topics: Adipose Tissue; Adult; Animals; Body Weight; Diabetes Mellitus, Type 2; Diet, High-Fat; Drug Evaluation, Preclinical; Energy Intake; Epididymis; Glucose; Glucosides; Humans; Hyperphagia; Hypoglycemic Agents; Insulin Resistance; Leptin; Lipids; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Non-alcoholic Fatty Liver Disease; Obesity; Organ Size; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Weight Loss | 2016 |
Ipragliflozin, a sodium-glucose cotransporter 2 inhibitor, ameliorates the development of liver fibrosis in diabetic Otsuka Long-Evans Tokushima fatty rats.
Topics: Animals; Body Weight; Cell Proliferation; Cells, Cultured; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Glucosides; Hepatic Stellate Cells; Hypoglycemic Agents; Insulin Resistance; Liver; Liver Cirrhosis, Experimental; Male; Obesity; Organ Size; Rats, Inbred OLETF; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2016 |
Low-carbohydrate diet combined with SGLT2 inhibitor for refractory hyperglycemia caused by insulin antibodies.
Topics: Adamantane; Aged; Benzhydryl Compounds; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Diet, Carbohydrate-Restricted; Drug Therapy, Combination; Glucosides; Humans; Hypoglycemic Agents; Insulin; Insulin Antibodies; Insulin Resistance; Male; Metformin; Nitriles; Pyrrolidines; Sodium-Glucose Transporter 2 Inhibitors; Vildagliptin | 2016 |
Sodium-Glucose Cotransporter 2 Inhibitor and a Low Carbohydrate Diet Affect Gluconeogenesis and Glycogen Content Differently in the Kidney and the Liver of Non-Diabetic Mice.
Topics: Animals; Body Weight; Cyclic AMP Response Element-Binding Protein; Diabetes Mellitus, Experimental; Diet, Carbohydrate-Restricted; Energy Intake; Fatty Acid Synthases; Forkhead Box Protein O1; Gluconeogenesis; Glucose Tolerance Test; Glucosides; Glycogen; Hyperglycemia; Insulin Resistance; Kidney; Lipid Metabolism; Liver; Male; Mice, Inbred C57BL; Obesity; RNA, Messenger; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Triglycerides; Up-Regulation | 2016 |
Distinct Glucose-Lowering Mechanisms of Ipragliflozin Depending on Body Weight Changes.
Topics: Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Glucosides; Homeostasis; Humans; Insulin Resistance; Insulin-Secreting Cells; Male; Middle Aged; Thiophenes | 2016 |
The protective role of liquiritin in high fructose-induced myocardial fibrosis via inhibiting NF-κB and MAPK signaling pathway.
Topics: Animals; Cell Survival; Collagen; Down-Regulation; Feeding Behavior; Fibrosis; Flavanones; Fructose; Glucosides; Inflammation; Insulin Resistance; Lipid Metabolism; Male; MAP Kinase Signaling System; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Myocardium; Myocytes, Cardiac; NF-kappa B; Protective Agents | 2016 |
The beneficial effects of empagliflozin, an SGLT2 inhibitor, on atherosclerosis in ApoE
Topics: Adipose Tissue; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Apolipoproteins E; Atherosclerosis; Benzhydryl Compounds; Blotting, Western; CD11c Antigen; Cell Line; Cell Proliferation; Diabetes Mellitus, Type 2; Diet, Western; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Insulin Resistance; Liver; Male; Mice; Rats; Real-Time Polymerase Chain Reaction; Sodium-Glucose Transporter 2 Inhibitors | 2017 |
Cyanidin-3-O-glucoside ameliorates palmitate-induced insulin resistance by modulating IRS-1 phosphorylation and release of endothelial derived vasoactive factors.
Topics: Anthocyanins; Antioxidants; Cells, Cultured; Endothelium, Vascular; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Insulin Receptor Substrate Proteins; Insulin Resistance; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Palmitic Acid; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Tyrosine | 2017 |
Anti-diabetic activities of cis- and trans-2,3,5,4'-tetrahydroxystilbene 2-O-β-glucopyranoside from Polygonum multiflorum.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Enzyme Inhibitors; Fallopia multiflora; Glucosides; Hep G2 Cells; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Phosphoenolpyruvate Carboxykinase (ATP); Stilbenes | 2017 |
Dapagliflozin improves insulin resistance and glucose intolerance in a novel transgenic rat model of chronic glucose overproduction and glucose toxicity.
Topics: Adipose Tissue, White; Adiposity; Animals; Benzhydryl Compounds; Cell Size; Gene Expression Regulation; Glucose Clamp Technique; Glucose Intolerance; Glucose Transporter Type 4; Glucosides; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Membrane Transport Modulators; Muscle, Skeletal; Phosphoenolpyruvate Carboxykinase (GTP); Rats, Transgenic; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Weight Gain | 2017 |
Beneficial effects of paeoniflorin on non-alcoholic fatty liver disease induced by high-fat diet in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Cytochrome P-450 CYP2E1; Diet, High-Fat; Disease Models, Animal; Glucosides; Insulin Resistance; Lipid Metabolism; Lipids; Liver; Male; Monoterpenes; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Rats; Reactive Oxygen Species; Signal Transduction | 2017 |
Remogliflozin etabonate, in a novel category of selective low-affinity sodium glucose cotransporter (SGLT2) inhibitors, exhibits antidiabetic efficacy in rodent models.
Topics: Animals; Chlorocebus aethiops; COS Cells; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glucose Tolerance Test; Glucosides; Glycosuria; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Pyrazoles; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2008 |
[Effects of total glucosides of paeony on enhancing insulin sensitivity and antagonizing nonalcoholic fatty liver in rats].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Glucose; Cholesterol, LDL; Cholinesterases; Drugs, Chinese Herbal; Enzyme Activation; Fatty Liver; Female; Glucose Tolerance Test; Glucosides; Insulin Resistance; Lipids; Liver; Male; Malondialdehyde; Paeonia; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2008 |
Hypoglycemic activity of a novel anthocyanin-rich formulation from lowbush blueberry, Vaccinium angustifolium Aiton.
Topics: Animals; Anthocyanins; Blood Glucose; Blueberry Plants; Drug Delivery Systems; Drug Therapy, Combination; Glucosides; Glycerides; Hypoglycemic Agents; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Organic Chemicals; Phenols; Plant Extracts | 2009 |
Inhibitory effect of paeoniflorin on the inflammatory vicious cycle between adipocytes and macrophages.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Bridged-Ring Compounds; Cell Line; Fatty Acids, Nonesterified; Glucosides; Inflammation; Insulin Resistance; Lipolysis; Macrophages; Mice; Monoterpenes; Tumor Necrosis Factor-alpha | 2012 |
Stevioside inhibits atherosclerosis by improving insulin signaling and antioxidant defense in obese insulin-resistant mice.
Topics: Adiponectin; Animals; Antioxidants; Atherosclerosis; Blood Glucose; Body Weight; Diterpenes, Kaurane; Glucosides; Insulin; Insulin Resistance; Mice; Mice, Obese; Obesity; Oxidative Stress; Signal Transduction; Sweetening Agents; Triglycerides | 2010 |
Cyanidin 3-glucoside attenuates obesity-associated insulin resistance and hepatic steatosis in high-fat diet-fed and db/db mice via the transcription factor FoxO1.
Topics: Adipokines; Adipose Tissue, White; Animals; Anthocyanins; Chemokine CCL2; Diet, High-Fat; Dietary Fats; Fatty Liver; Forkhead Box Protein O1; Forkhead Transcription Factors; Glucosides; Hypoglycemic Agents; Insulin Resistance; Interleukin-6; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Signal Transduction; Triglycerides; Tumor Necrosis Factor-alpha | 2012 |
Carboxymethyl flavonoids and a monoterpene glucoside from Selaginella moellendorffii.
Topics: Animals; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Flavanones; Flavones; Flavonoids; Glucose; Glucosides; Insulin Resistance; Molecular Structure; Monoterpenes; Myoblasts; Phytotherapy; Plant Extracts; Rats; Selaginellaceae | 2011 |
Stevioside ameliorates high-fat diet-induced insulin resistance and adipose tissue inflammation by downregulating the NF-κB pathway.
Topics: Adipose Tissue; Animals; Cytokines; Diet, High-Fat; Diterpenes, Kaurane; Down-Regulation; Glucose Tolerance Test; Glucosides; Inflammation; Insulin; Insulin Resistance; Macrophages; Male; Mice; Mice, Inbred C57BL; NF-kappa B; RNA, Messenger; Sweetening Agents | 2012 |
Homoplantaginin modulates insulin sensitivity in endothelial cells by inhibiting inflammation.
Topics: Anti-Inflammatory Agents; Cell Survival; Cells, Cultured; Endothelial Cells; Flavonoids; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; I-kappa B Kinase; Inflammation; Insulin Receptor Substrate Proteins; Insulin Resistance; Interleukin-6; Nitric Oxide; Nitric Oxide Synthase Type III; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; RNA, Messenger; Tumor Necrosis Factor-alpha | 2012 |
[D-Leu-4]-OB3, a synthetic peptide amide with leptin-like activity, augments the effects of orally delivered exenatide and pramlintide acetate on energy balance and glycemic control in insulin-resistant male C57BLK/6-m db/db mice.
Topics: Administration, Oral; Animals; Anti-Obesity Agents; Blood Glucose; Body Weight; Drug Combinations; Drug Synergism; Eating; Energy Metabolism; Exenatide; Glucosides; Hypoglycemic Agents; Insulin; Insulin Resistance; Islet Amyloid Polypeptide; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Peptide Fragments; Peptides; Venoms | 2012 |
Dietary cyanidin 3-O-beta-D-glucoside-rich purple corn color prevents obesity and ameliorates hyperglycemia in mice.
Topics: Adipose Tissue; Animals; Anthocyanins; Base Sequence; Body Weight; CCAAT-Enhancer-Binding Proteins; Diet; DNA Primers; DNA-Binding Proteins; Energy Intake; Glucosides; Hyperglycemia; Insulin Resistance; Lipids; Liver; Male; Mice; Mice, Inbred BALB C; Obesity; Organ Size; Sterol Regulatory Element Binding Protein 1; Transcription Factors | 2003 |
Effects of stevioside on glucose transport activity in insulin-sensitive and insulin-resistant rat skeletal muscle.
Topics: Animals; Biological Transport; Blood Glucose; Deoxyglucose; Diterpenes; Diterpenes, Kaurane; Fatty Acids, Nonesterified; Female; Glucose; Glucose Tolerance Test; Glucosides; Hypoglycemic Agents; Insulin; Insulin Resistance; Muscle, Skeletal; Obesity; Rats; Rats, Zucker | 2004 |
Long-term treatment with the Na+-glucose cotransporter inhibitor T-1095 causes sustained improvement in hyperglycemia and prevents diabetic neuropathy in Goto-Kakizaki Rats.
Topics: Administration, Oral; Animals; Carbonates; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diet; Disease Models, Animal; Enzyme Inhibitors; Female; Glucose; Glucose Tolerance Test; Glucosides; Hyperglycemia; Insulin Resistance; Male; Membrane Glycoproteins; Monosaccharide Transport Proteins; Rats; Rats, Inbred Strains; Rats, Wistar; Sodium; Sodium-Glucose Transporter 1; Time Factors | 2005 |
Stevioside does not cause increased basal insulin secretion or beta-cell desensitization as does the sulphonylurea, glibenclamide: studies in vitro.
Topics: Animals; Diterpenes, Kaurane; Female; Glucose; Glucosides; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred Strains | 2006 |
Increase of insulin sensitivity by stevioside in fructose-rich chow-fed rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dietary Carbohydrates; Diterpenes, Kaurane; Fructose; Glucose Tolerance Test; Glucosides; Insulin Resistance; Male; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Stevia; Tolbutamide | 2005 |
Cyanidin 3-glucoside ameliorates hyperglycemia and insulin sensitivity due to downregulation of retinol binding protein 4 expression in diabetic mice.
Topics: Adipokines; Adiponectin; Adipose Tissue, White; Animals; Anthocyanins; Blood Glucose; Blotting, Western; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Down-Regulation; Glucose Tolerance Test; Glucose Transporter Type 4; Glucose-6-Phosphatase; Glucosides; Hyperglycemia; Inflammation Mediators; Insulin Resistance; Liver; Male; Mice; Mice, Inbred Strains; Molecular Structure; Receptors, Adiponectin; Retinol-Binding Proteins, Plasma; Reverse Transcriptase Polymerase Chain Reaction | 2007 |
Cyanidin 3-glucoside protects 3T3-L1 adipocytes against H2O2- or TNF-alpha-induced insulin resistance by inhibiting c-Jun NH2-terminal kinase activation.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Anthocyanins; Glucose; Glucosides; Hydrogen Peroxide; Insulin; Insulin Resistance; Mice; Mitogen-Activated Protein Kinase 8; Protective Agents; Reactive Oxygen Species; RNA, Small Interfering; Tumor Necrosis Factor-alpha | 2008 |
Hyperglycemia contributes insulin resistance in hepatic and adipose tissue but not skeletal muscle of ZDF rats.
Topics: Adipocytes; Adipose Tissue; Animals; Blood Glucose; Carbonates; Diabetes Mellitus; Glucokinase; Glucose Transporter Type 4; Glucose-6-Phosphatase; Glucosides; Hyperglycemia; Hyperinsulinism; Insulin Resistance; Liver; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Obesity; Rats; Rats, Zucker | 2000 |
Correction of hyperglycemia and insulin sensitivity by T-1095, an inhibitor of renal Na+-glucose cotransporters, in streptozotocin-induced diabetic rats.
Topics: Animals; Carbonates; Deoxyglucose; Diabetes Mellitus, Experimental; Glucosides; Hyperglycemia; Hypoglycemic Agents; In Vitro Techniques; Insulin Resistance; Lactic Acid; Male; Monosaccharide Transport Proteins; Muscle, Skeletal; Rats | 2000 |
Antidiabetic activity of a xanthone compound, mangiferin.
Topics: Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucosides; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Magnoliopsida; Male; Mice; Phytotherapy; Plant Extracts; Xanthenes; Xanthones | 2001 |