Compounds > glucose, (beta-d)-isomer
Page last updated: 2024-08-24

glucose, (beta-d)-isomer and Hyperglycemia, Postprandial

glucose, (beta-d)-isomer has been researched along with Hyperglycemia, Postprandial in 139 studies

Research

Studies (139)

TimeframeStudies, this research(%)All Research%
pre-19902 (1.44)18.7374
1990's2 (1.44)18.2507
2000's23 (16.55)29.6817
2010's96 (69.06)24.3611
2020's16 (11.51)2.80

Authors

AuthorsStudies
Basyreva, LY; Gusev, SA; Lipatova, VA; Mikhalchik, EV; Panasenko, OM; Sergienko, VI1
Anjos, PM; Fagundes-Netto, FS; Nogueira-Machado, JA; Volpe, CM1
Karumuthil-Melethil, S; Li, R; Perez, N; Vasu, C1
Caldon, N; Gao, L; Gyurko, R; Kantarci, A; Siqueira, CC; Van Dyke, TE1
Ding, Y; Hasturk, H; Kantarci, A; Malabanan, A; Trackman, PC; Van Dyke, TE1
Cech, P; Frei, J; Markert, M1
Blodgett, JL; Bloodworth, RC; McManus, LM; Pinckard, RN; Prihoda, TJ1
Sahu, JK; Sharma, S; Suryavanshi, VD1
Haluzik, M; Hüttl, M; Malinska, H; Markova, I; Miklankova, D; Poruba, M; Vaněčkova, I; Zapletalova, I1
Faridvand, Y; Jodati, A; Kazemzadeh, H; Maroufi, NF; Mirzajanzadeh, P; Nejabati, HR; Nouri, M; Pezeshkian, M; Safaie, N; Vahedian, V1
Dixen, U; Fenger, M; Goetze, JP; Holst, JJ; Jørgensen, NB; Madsbad, S; Madsen, PL; Richter, EA; Thirumathyam, R; Van Hall, G; Vejlstrup, N1
Chen, F; Deng, R; Jiang, K; Liang, J; Lu, Y; Miao, Y; Qian, J; Shen, L; Su, F; Wang, D; Xiang, Y1
Cowen, J; Leader, R; Rajeev, SP1
Huang, L; Li, N; Liu, W; Miao, J; Wang, L; Yu, J1
Abdel-Latif, RG; Amin, EF; Rifaai, RA1
Abdalla, O; Dessouki, A; Kilany, O; Sasaki, K; Sayed, N; Shimoda, M; Yoshida, T1
Moorthy, M; Palanisamy, UD; Perera, A; Ton, SH1
Berretta, M; Bonelli, A; Botti, G; Caronna, A; Cocco, S; Conforti, G; De Laurentiis, M; Lombari, MC; Maurea, N; Quagliariello, V; Rea, G1
Aaron, M; Collins, SP; Cox, ZL; Davidson, BT; Fowler, M; Hernandez, GA; Iii, ATM; Jenkins, CA; Jr, FEH; Kampe, C; Lindenfeld, J; Lindsell, CJ; Miller, KF; Stubblefield, WB1
Habu, M; Kurozumi, A; Okada, Y; Tanaka, Y1
Fukuda, S; Ishii, Y; Kemmochi, Y; Kuroki, F; Miyajima, K; Nakae, D; Ohta, T; Sano, R; Sasase, T; Sugimoto, M; Yamanaka, M; Yasui, Y1
Kurokawa, M; Sugita, C; Tsuhako, R; Yoshida, H1
Domon, A; Katayama, K; Sato, T; Suzuki, H; Tazaki, H; Tochigi, Y1
Akhtar, M; Ali, J; Khan, S; Khan, T; Najmi, AK1
Arsenović, M; Čapo, I; Ilić, V; Milijašević, B; Stilinović, N; Vukmirović, S1
Jain, RK1
Ahn, YB; Cha, SA; Ko, SH; Lim, TS; Park, YM; Song, KH; Yoo, KD; Yun, JS1
Staels, B2
Al-Sayed, E; Albert, A; Ganesan, D; Govindan Sadasivam, S; Paul, E; Saso, L; Singab, ANB1
Abdul-Ghani, M; Chilton, R; DeFronzo, RA; Del Prato, S; Ryder, REJ; Singh, R1
de Zeeuw, D; Heerspink, HJL; Laverman, GD; Petrykiv, S1
Birkeland, KI; Bodegard, J; Carstensen, B; Eriksson, JW; Fenici, P; Gulseth, HL; Jørgensen, ME; Nathanson, D; Norhammar, A; Nyström, T; Persson, F; Thuresson, M1
Takeishi, S; Takekoshi, S; Tsuboi, H1
Chen, L; Tian, D; Wang, L; Xia, P; Xu, L; Zhao, Y; Zheng, H1
Biavatti, MW; Bortoluzzi, AJ; Frederico, MJ; Pollo, LAE; Silva, FRMB1
Brown, F; McColl, T1
Brandjes, DPM; Gerards, MC; Gerdes, VEA; Hageman, IMG; Hoekstra, JBL; Kross, M; Patberg, KW; Potter van Loon, BJ; Snijders, D; Venema, GE; Vriesendorp, TM1
Matsuba, I; Matsuba, R; Nagai, Y; Shimokawa, M; Tanaka, Y1
Gunji, R; Kaku, K; Senda, M; Tamura, M; Terauchi, Y1
Íbias, J; Nazarian, A; O'Dell, LE1
Cherney, DZI; Thomas, MC1
Lu, W; Wang, M; Wang, S; Yao, D1
Guo, X; Li, D; Li, J; Li, S; Ren, G; Wang, N; Zhang, T1
Hasch, A; Jene, T; Miederer, I; Müller, MB; Treccani, G; van der Kooij, MA; Voelxen, N; Walenta, S1
Jang, HH; Kim, HW; Kim, JB; Kim, SM; Kim, SY; Lee, YM1
Chen, B; Chen, X; Tong, L; Zhang, J; Zhang, Y1
Naik, PR; Nandini, HS1
Ariyanti, AD; Kasim, V; Marcelina, O; Nugrahaningrum, DA; Wang, G; Wu, S; Zhang, J1
Castilho, PC; Llorent-Martínez, EJ; Spínola, V1
Han, H; Jiang, S; Shao, Y; Tao, J; Wei, W; Yue, H; Zhang, T; Zhao, X; Zhou, G1
Hirata, Y; Hosooka, T; Imamura, M; Kobayashi, K; Minokoshi, Y; Nomura, K; Ogawa, W; Okada, Y; Okamoto, S; Senga, Y; Takeda, S1
Buggs, J; Cheng, F; Jiang, S; Koepsell, H; Liu, R; Vallon, V; Wang, L; Wei, J; Xu, L; Zhang, J1
Boeder, S; Edelman, SV1
Huang, Y; Li, DD; Song, YW; Wang, JS; Yin, HJ; Zhang, L; Zhang, S; Zhang, YH1
Ghosh, A; Heise, T; Plum-Mörschel, L; Polidori, D; Rothenberg, P; Sha, S1
Hayashizaki, Y; Imamura, M; Kihara, R; Kobayashi, Y; Kurosaki, E; Li, Q; Noda, A; Sasamata, M; Shibasaki, M; Tahara, A; Takasu, T; Tomiyama, H; Yamajuku, D; Yokono, M2
Hach, T; Hantel, S; Jelaska, A; Pinnetti, S; Rosenstock, J; Seman, LJ; Woerle, HJ1
Gerasimova, M; Koepsell, H; Masuda, T; Mayoux, E; Rieg, T; Rose, MA; Satriano, J; Thomson, SC; Vallon, V1
Liu, X; Tan, J; Wang, B; Xiao, L; Yang, X; Zhou, X; Zhu, L1
Abdul-Ghani, MA; Daniele, G; DeFronzo, RA; Eldor, R; Fiorentino, TV; Merovci, A; Norton, L; Perez, Z; Solis-Herrera, C; Tripathy, D; Xiong, J1
Condren, AB; Donahue, EP; Farmer, TD; Healey, EC; Kim, K; McCoy, GA; O'Brien, TP; Printz, RL; Shiota, M; Ueta, K1
Tahrani, AA1
Beckers, J; Hrabé de Angelis, M; Huypens, P; Neschen, S; Rathkolb, B; Scheerer, M; Schultheiss, J; Seelig, A; Suhre, K; Wolf, E; Wu, M; Wurst, W1
Dieu Van, NK; Han, P; Ji, L; Liu, Y; Meininger, G; Qiu, R; Vijapurkar, U; Yang, G1
Burgess, L; de Bruin, TW; Hamer-Maansson, JE; Hruba, V; Korányi, L; Schumm-Draeger, PM1
Arakawa, K; Hikida, K; Kakimoto, T; Kimata, H; Kuriyama, C; Lee, SP; Matsushita, Y; Nakayama, K; Qi, J; Saito, A; Shiotani, M; Taniuchi, N; Ueta, K; Watanabe, Y; Xu, JZ1
Dobbins, R; Dorey, DJ; Kler, L; Lorimer, JD; O'Connor-Semmes, R; Sykes, AP; Walker, S; Wilkison, WO1
Almond, SR; Dobbins, R; Kemp, GL; Kler, L; O'Connor-Semmes, R; Sykes, AP; Walker, S; Wilkison, WO1
Bogle, A; Chalamandaris, AG; Edelman, S; Griffen, SC; Henry, RR; Iqbal, N; Kasichayanula, S; List, J; Mudaliar, S; Rosenstock, J1
Katakami, N; Matsuoka, TA; Shimomura, I; Shiraiwa, T; Takahara, M1
Airoldi, C; Cabrita, EJ; de Almeida, RF; Dias, C; Jesus, AR; Jiménez-Barbero, J; Macedo, MP; Marcelo, F; Martins, A; Matos, AM; Nicotra, F; Rauter, AP; Ribeiro, RT; Viana, AS1
Cherney, DZ; Lytvyn, Y; Perkins, BA; Škrtić, M; Yang, GK; Yip, PM1
Abdul-Ghani, M; Chavez-Velazquez, A; Daniele, G; DeFronzo, RA; Mari, A; Merovci, A; Solis-Herrera, C; Tripathy, D; Urban McCarthy, S; Xiong, J1
Prázný, M; Slíva, J1
Bergenheim, K; Callan, L; Charokopou, M; Lister, S; McEwan, P; Postema, R; Roudaut, M; Tolley, K; Townsend, R1
Alameddine, A; Ayer, A; Bourreau, J; Custaud, MA; Derbre, S; Fajloun, Z; Gauguier, D; Gauquelin-Koch, G; Navasiolava, N; Yuan, M1
Du, W; Huang, B; Jiang, Q; Liu, C; Qiu, H; Tang, C; Wu, Y; Xue, L1
Solini, A1
Broedl, UC; Christiansen, AV; Häring, HU; Kim, G; Meinicke, T; Merker, L; Roux, F; Salsali, A; Woerle, HJ1
Woo, V1
Chirila, C; Davenport, E; Hach, T; Kaschinski, D; Palencia, R; Pfarr, E; Zheng, Q1
Vivian, E1
Hirano, T; Hiromura, M; Kohashi, K; Kushima, H; Mori, Y; Nagashima, M; Terasaki, M; Watanabe, T1
Blumberg, JB; Chen, CY; Hashimoto, N1
Hayashizaki, Y; Takakura, S; Takasu, T; Toyoshi, T1
Guo, S; Jiang, K; Liu, X; Luo, L; Shen, N; Sun, C; Wang, C; Wang, M; Xu, M; Yang, Y; Yao, L1
Bando, H; Horasawa, S; Kawasumi, K; Ohashi, K; Osame, K; Saito, S1
Abiko, A; Atageldiyeva, K; Fujita, Y; Haneda, M; Honjo, J; Makino, Y; Mizumoto, K; Takeda, Y; Takiyama, Y; Yanagimachi, T1
Patel, BM; Shah, NR1
Ashida, H; Ito, C; Nanba, F; Toda, T; Wang, L; Yamashita, Y1
Ahn, YB; Chung, S; Kim, ES; Kim, JW; Kim, MJ; Kim, SJ; Ko, SH; Lee, EM; Moon, SD; Shin, SJ; Yoo, YH1
Kato, H; Nagai, Y; Ohta, A; Sada, Y; Tanaka, Y1
Davidson, JA; Sloan, L1
Atsumi, T; Miyoshi, H; Nakamura, A; Takase, T; Yamamoto, C1
Ayer, A; Cariou, B; Charpentier, F; Dollet, L; Jagu, B; Joubert, M; Le May, C; Magré, J; Manrique, A; Marechal, X; Montaigne, D; Prieur, X; Staels, B; Tesse, A; Toumaniantz, G1
Andrikopoulos, S; Joannides, CN; Lamont, BJ; Mangiafico, SP; Waters, MF1
Avogaro, A; Fioretto, P1
Gause-Nilsson, I; Johnsson, E; Kosiborod, M; Sonesson, C; Xu, J1
Alzaid, A1
Chatsudthipong, V; Muanprasat, C1
Fiedorek, FT; List, JF; Morales, E; Tang, W; Woo, V1
Donnelly, R; Idris, I1
Cai, F; Jia, Y; Li, C; Li, J; Liu, Q; Tang, J; Wang, C; Yang, Y; Zhao, X1
Jones, HB; Macdonald, FR; Mayers, RM; Peel, JE; Poucher, SM; Westgate, L; Whaley, JM1
Chang, CC; Chao, YS; Chen, CT; Chiu, CH; Chu, KF; Hsiao, WC; Hsieh, CJ; Hsieh, TC; Huang, CY; Hung, MS; Lee, JC; Liu, YW; Song, JS; Tsai, CH; Wang, MH; Wu, SH; Yao, CH; Yeh, TK; Yuan, MC1
Cekic, V; Jakovljevic, V; Mikov, M; Sabo, A; Vasovic, V1
Cassader, M; Gambino, R; Musso, G; Pagano, G1
Kadokura, T; Krauwinkel, WJ; Smulders, RA; Veltkamp, SA1
Jia, Q; Wang, Y; Xia, M; Zhang, Y; Zhu, W1
Chen, KS; Li, X; Sun, CD; Wu, YL; Xu, CJ; Zhang, B; Zhang, JK1
Arakawa, K; Conway, B; Conway, J; Demarest, K; Du, F; Kuriyama, C; Liang, Y; Liu, Y; Martin, T; Matsushita, Y; Polidori, D; Ueta, K; Ways, K; Xu, J1
Fukazawa, M; Fukuzawa, T; Hagita, H; Honda, K; Ikeda, S; Kawabe, Y; Kawai, M; Kawai, T; Kobayashi, T; Ozawa, K; Sato, T; Suzuki, M; Takeda, M; Yata, T1
Fushimi, N; Isaji, M; Ishikawa-Takemura, Y; Itoh, F; Shibazaki, T; Tomae, M; Yamada, M1
Guo, H; Guo, J; Jiang, X; Li, Z; Ling, W1
Gao, B; Gao, H; Huang, YN; Jia, LR; Xie, WJ; Zhang, Y; Zhao, DD; Zhong, K; Zhu, RX1
Fujikura, H; Fushimi, N; Isaji, M; Ishikawa-Takemura, Y; Itoh, F; Kamada, N; Kobayashi, S; Miyagi, T; Nakabayashi, T; Ohno, K; Ozawa, T; Shibazaki, T; Shimizu, K; Shiohara, H; Teranishi, H; Tomae, M; Yonekubo, S1
Fukazawa, M; Honda, K; Ikeda, S; Kato, M; Kawabe, Y; Kawai, M; Mitsui, T; Murao, N; Nagata, T; Suzuki, Y; Yamaguchi, K; Yamane, M; Yata, T1
Hantel, S; Heise, T; Macha, S; Pinnetti, S; Seewaldt-Becker, E; Seman, L; Woerle, HJ1
Abbott, TP; Baek, JS; Kim, HY; Lee, SB; Moon, TW; Park, CS; Park, KH1
Aoki, H; Horio, F; Osawa, T; Tsuda, T; Uchida, K1
Arakawa, K; Fujita, T; Ishihara, T; Matsumoto, Y; Nawano, M; Oku, A; Saito, A; Ueta, K1
Arakawa, K; Nishiyama, S; Oku, A; Saito, A; Ueta, K; Yoneda, H1
Donahue, EP; Fujimoto, Y; Shiota, M; Torres, TP1
Che, CT; Cheng, CH; Lau, CB; Leung, PS; Li, JM1
Ashida, H; Fukuda, I; Horio, F; Hoshino, H; Ichi, T; Isa, Y; Kadowaki, M; Nishimura, N; Nishiumi, S; Sasaki, R; Tanaka, A; Tsuda, T1
Cheng, JT; Hsu, FL; Liu, IM; Niu, HS1
McCann, P; Meezan, E; Pillion, DJ; Wang, P; Yorks, J1
Anai, M; Arakawa, K; Asano, T; Funaki, M; Kikuchi, M; Nawano, M; Oka, Y; Oku, A; Saito, A; Ueta, K1
Anai, M; Arakawa, K; Asano, T; Ishirahara, T; Kikuchi, M; Nawano, M; Oku, A; Saito, A; Ueta, K; Umebayashi, I1
Prasad, K1
Adachi, T; Iwakura, I; Kitamura, K; Okamoto, Y; Oku, A; Saito, A; Seino, Y; Shihara, N; Tsuda, K; Ueta, K; Yamada, Y; Yano, H; Yasuda, K1
Adachi, T; Arakawa, K; Ikezawa, K; Kano-Ishihara, T; Matsumoto, T; Oku, A; Saito, A; Tsuda, K; Ueta, K; Yasuda, K1
Adachi, T; Arakawa, K; Kano-Ishihara, T; Matsumoto, M; Oku, A; Saito, A; Tsuda, K; Ueta, K; Yasuda, K1
Kim, JS; Kwon, CS; Son, KH1
Alstrup, KK; Gregersen, S; Hermansen, K; Jeppesen, PB1
Adachi, T; Fujimoto, S; Mukai, E; Nunoi, K; Okamoto, Y; Oku, A; Seino, Y; Shihara, N; Suzuki, N; Tamon, A; Tsuda, K; Yasuda, K1
Caspary, WF1

Reviews

14 review(s) available for glucose, (beta-d)-isomer and Hyperglycemia, Postprandial

ArticleYear
Review on Characteristics and Analytical Methods of Remogliflozin Etabonate: An Update.
    Mini reviews in medicinal chemistry, 2022, Volume: 22, Issue:9

    Topics: Chromatography, Liquid; Diabetes Mellitus, Type 2; Glucosides; Humans; Hyperglycemia; Hypoglycemic Agents; Pyrazoles; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Tandem Mass Spectrometry

2022
Cardiovascular Protection by Sodium Glucose Cotransporter 2 Inhibitors: Potential Mechanisms.
    The American journal of medicine, 2017, Volume: 130, Issue:6S

    Topics: Benzhydryl Compounds; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Cardiomyopathies; Glucosides; Hemodynamics; Hormones; Humans; Hyperglycemia; Hypoglycemic Agents; Sodium-Glucose Transporter 2 Inhibitors

2017
Cardiovascular Protection by Sodium Glucose Cotransporter 2 Inhibitors: Potential Mechanisms.
    The American journal of cardiology, 2017, 07-01, Volume: 120, Issue:1S

    Topics: Benzhydryl Compounds; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Cardiomyopathies; Glucosides; Hemodynamics; Hormones; Humans; Hyperglycemia; Hypoglycemic Agents; Sodium-Glucose Transporter 2 Inhibitors

2017
Effects of sodium-glucose co-transporter 2 (SGLT2) inhibitors on serum uric acid level: A meta-analysis of randomized controlled trials.
    Diabetes, obesity & metabolism, 2018, Volume: 20, Issue:2

    Topics: Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus, Type 2; Glucosides; Humans; Hyperglycemia; Hyperuricemia; Hypoglycemia; Hypoglycemic Agents; Membrane Transport Modulators; Randomized Controlled Trials as Topic; Sodium-Glucose Transporter 2; Uric Acid

2018
The actions of SGLT2 inhibitors on metabolism, renal function and blood pressure.
    Diabetologia, 2018, Volume: 61, Issue:10

    Topics: Adiposity; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glomerular Filtration Rate; Glucosides; Humans; Hyperglycemia; Hypoglycemic Agents; Kidney; Kidney Function Tests; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Weight Loss

2018
Sodium-glucose co-transporter inhibitors as adjunctive treatment to insulin in type 1 diabetes: A review of randomized controlled trials.
    Diabetes, obesity & metabolism, 2019, Volume: 21 Suppl 2

    Topics: Adult; Benzhydryl Compounds; Blood Glucose; Body Mass Index; Body Weight; Canagliflozin; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Double-Blind Method; Drug Therapy, Combination; Female; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Sodium-Glucose Transporter 2 Inhibitors; Treatment Outcome

2019
Extra-glycaemic properties of empagliflozin.
    Diabetes/metabolism research and reviews, 2016, Volume: 32, Issue:3

    Topics: Benzhydryl Compounds; Diabetes Mellitus, Type 2; Glucosides; Humans; Hyperglycemia; Hypoglycemic Agents

2016
Empagliflozin/linagliptin single-tablet combination: first-in-class treatment option.
    International journal of clinical practice, 2015, Volume: 69, Issue:12

    Topics: Benzhydryl Compounds; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Combinations; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Linagliptin; Randomized Controlled Trials as Topic

2015
Sodium-Glucose Cotransporter 2 Inhibitors in the Treatment of Type 2 Diabetes Mellitus.
    The Diabetes educator, 2015, Volume: 41, Issue:1 Suppl

    Topics: Benzhydryl Compounds; Blood Glucose; Canagliflozin; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Glucosides; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin; Kidney; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors

2015
Fixed-Dose Combination of Canagliflozin and Metformin for the Treatment of Type 2 Diabetes: An Overview.
    Advances in therapy, 2017, Volume: 34, Issue:1

    Topics: Blood Glucose; Blood Pressure; Body Weight; Canagliflozin; Clinical Trials, Phase III as Topic; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Glucosides; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Metformin; Sodium-Glucose Transporter 2 Inhibitors

2017
Dapagliflozin: potential beneficial effects in the prevention and treatment of renal and cardiovascular complications in patients with type 2 diabetes.
    Expert opinion on pharmacotherapy, 2017, Volume: 18, Issue:5

    Topics: Benzhydryl Compounds; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glucosides; Humans; Hyperglycemia; Hypoglycemic Agents; Kidney Failure, Chronic; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors

2017
Stevioside and related compounds: therapeutic benefits beyond sweetness.
    Pharmacology & therapeutics, 2009, Volume: 121, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Carcinogens; Diterpenes, Kaurane; Diuretics; Drug Interactions; Glucosides; Humans; Hyperglycemia; Hypertension; Ion Pumps; Sweetening Agents

2009
Sodium-glucose co-transporter-2 inhibitors: an emerging new class of oral antidiabetic drug.
    Diabetes, obesity & metabolism, 2009, Volume: 11, Issue:2

    Topics: Animals; Benzhydryl Compounds; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucosides; Humans; Hyperglycemia; Hypoglycemic Agents; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors

2009
A novel approach to control hyperglycemia in type 2 diabetes: sodium glucose co-transport (SGLT) inhibitors: systematic review and meta-analysis of randomized trials.
    Annals of medicine, 2012, Volume: 44, Issue:4

    Topics: Benzhydryl Compounds; Blood Pressure; Body Mass Index; Canagliflozin; Diabetes Mellitus, Type 2; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Randomized Controlled Trials as Topic; Sodium-Glucose Transport Proteins; Thiophenes

2012

Trials

21 trial(s) available for glucose, (beta-d)-isomer and Hyperglycemia, Postprandial

ArticleYear
Investigating the roles of hyperglycaemia, hyperinsulinaemia and elevated free fatty acids in cardiac function in patients with type 2 diabetes via treatment with insulin compared with empagliflozin: protocol for the HyperCarD2 randomised, crossover trial
    BMJ open, 2022, 08-11, Volume: 12, Issue:8

    Topics: Benzhydryl Compounds; Cardiovascular Diseases; Cross-Over Studies; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Glucose; Glucosides; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Insulin; Randomized Controlled Trials as Topic; Sodium-Glucose Transporter 2 Inhibitors; Stroke Volume; Ventricular Function, Left

2022
Efficacy and safety of dapagliflozin in acute heart failure: Rationale and design of the DICTATE-AHF trial.
    American heart journal, 2021, Volume: 232

    Topics: Acute Disease; Benzhydryl Compounds; Diabetes Mellitus, Type 2; Diabetic Ketoacidosis; Disease Progression; Glucosides; Heart Failure; Hospital Mortality; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Hypotension; Hypovolemia; Insulin; Natriuresis; Natriuretic Peptide, Brain; Patient Readmission; Peptide Fragments; Randomized Controlled Trials as Topic; Renal Insufficiency, Chronic; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Treatment Outcome; Weight Loss

2021
Comparison of tofogliflozin 20 mg and ipragliflozin 50 mg used together with insulin glargine 300 U/mL using continuous glucose monitoring (CGM): A randomized crossover study.
    Endocrine journal, 2017, Oct-28, Volume: 64, Issue:10

    Topics: Activities of Daily Living; Aged; Benzhydryl Compounds; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glucosides; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin Glargine; Japan; Male; Membrane Transport Modulators; Middle Aged; Monitoring, Ambulatory; Risk; ROC Curve; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes

2017
Dapagliflozin for prednisone-induced hyperglycaemia in acute exacerbation of chronic obstructive pulmonary disease.
    Diabetes, obesity & metabolism, 2018, Volume: 20, Issue:5

    Topics: Aged; Benzhydryl Compounds; Combined Modality Therapy; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Glucocorticoids; Glucose; Glucosides; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Length of Stay; Male; Middle Aged; Monitoring, Ambulatory; Prednisone; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Sodium-Glucose Transporter 2 Inhibitors; Subcutaneous Tissue

2018
Tofogliflozin decreases body fat mass and improves peripheral insulin resistance.
    Diabetes, obesity & metabolism, 2018, Volume: 20, Issue:5

    Topics: Adiposity; Anti-Obesity Agents; Benzhydryl Compounds; Biomarkers; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Electric Impedance; Glucose Clamp Technique; Glucosides; Glycated Hemoglobin; Hyperglycemia; Hypoglycemia; Insulin Resistance; Overweight; Sodium-Glucose Transporter 2 Inhibitors; Weight Loss

2018
Long-term safety and efficacy of tofogliflozin as add-on to insulin in patients with type 2 diabetes: Results from a 52-week, multicentre, randomized, double-blind, open-label extension, Phase 4 study in Japan (J-STEP/INS).
    Diabetes, obesity & metabolism, 2018, Volume: 20, Issue:5

    Topics: Adult; Aged; Benzhydryl Compounds; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Follow-Up Studies; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Incidence; Insulin; Insulin Resistance; Japan; Male; Middle Aged; Risk; Sodium-Glucose Transporter 2 Inhibitors; Young Adult

2018
Validation of a novel method for determining the renal threshold for glucose excretion in untreated and canagliflozin-treated subjects with type 2 diabetes mellitus.
    The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:5

    Topics: Blood Glucose; Body Mass Index; Canagliflozin; Diabetes Mellitus, Type 2; Female; Glomerular Filtration Rate; Glucosides; Glycosuria; Humans; Hyperglycemia; Hypoglycemic Agents; Kidney; Kidney Function Tests; Male; Membrane Transport Modulators; Middle Aged; Overweight; Postprandial Period; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes

2013
Efficacy and safety of empagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, as add-on to metformin in type 2 diabetes with mild hyperglycaemia.
    Diabetes, obesity & metabolism, 2013, Volume: 15, Issue:12

    Topics: Analysis of Variance; Benzhydryl Compounds; Blood Pressure; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Glucosides; Glycated Hemoglobin; Hematocrit; Humans; Hyperglycemia; Hypoglycemic Agents; Male; Metformin; Middle Aged; Sodium-Glucose Transporter 2 Inhibitors; Treatment Outcome

2013
Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production.
    The Journal of clinical investigation, 2014, Volume: 124, Issue:2

    Topics: Benzhydryl Compounds; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Fasting; Glucagon; Glucose; Glucose Clamp Technique; Glucosides; Humans; Hyperglycemia; Insulin; Male; Metformin; Middle Aged; Muscles; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Sulfonylurea Compounds; Time Factors

2014
Canagliflozin in Asian patients with type 2 diabetes on metformin alone or metformin in combination with sulphonylurea.
    Diabetes, obesity & metabolism, 2015, Volume: 17, Issue:1

    Topics: Aged; Canagliflozin; China; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Resistance; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Malaysia; Male; Membrane Transport Modulators; Metformin; Middle Aged; Sodium-Glucose Transporter 2 Inhibitors; Sulfonylurea Compounds; Thiophenes; Vietnam

2015
Twice-daily dapagliflozin co-administered with metformin in type 2 diabetes: a 16-week randomized, placebo-controlled clinical trial.
    Diabetes, obesity & metabolism, 2015, Volume: 17, Issue:1

    Topics: Aged; Benzhydryl Compounds; Body Weight; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Europe; Feasibility Studies; Female; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Male; Membrane Transport Modulators; Metformin; Middle Aged; Sodium-Glucose Transporter 2 Inhibitors; South Africa

2015
Randomized trial showing efficacy and safety of twice-daily remogliflozin etabonate for the treatment of type 2 diabetes.
    Diabetes, obesity & metabolism, 2015, Volume: 17, Issue:1

    Topics: Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Follow-Up Studies; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypertriglyceridemia; Hypoglycemia; Hypoglycemic Agents; Intention to Treat Analysis; Membrane Transport Modulators; Middle Aged; Patient Dropouts; Pioglitazone; Prodrugs; Pyrazoles; Sodium-Glucose Transporter 2 Inhibitors; Thiazolidinediones; Weight Loss

2015
Randomized efficacy and safety trial of once-daily remogliflozin etabonate for the treatment of type 2 diabetes.
    Diabetes, obesity & metabolism, 2015, Volume: 17, Issue:1

    Topics: Cohort Studies; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Follow-Up Studies; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Intention to Treat Analysis; Membrane Transport Modulators; Middle Aged; Patient Dropouts; Pioglitazone; Prodrugs; Pyrazoles; Sodium-Glucose Transporter 2 Inhibitors; Thiazolidinediones; Weight Loss

2015
Exploring the potential of the SGLT2 inhibitor dapagliflozin in type 1 diabetes: a randomized, double-blind, placebo-controlled pilot study.
    Diabetes care, 2015, Volume: 38, Issue:3

    Topics: Adolescent; Adult; Aged; Area Under Curve; Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus, Type 1; Double-Blind Method; Female; Glucosides; Glycated Hemoglobin; Glycosuria; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Middle Aged; Pilot Projects; Sodium-Glucose Transporter 2 Inhibitors; Treatment Outcome; Young Adult

2015
Dapagliflozin lowers plasma glucose concentration and improves β-cell function.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:5

    Topics: Benzhydryl Compounds; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Glucose Tolerance Test; Glucosides; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Male; Middle Aged; Treatment Outcome

2015
The cost-effectiveness of dapagliflozin versus sulfonylurea as an add-on to metformin in the treatment of Type 2 diabetes mellitus.
    Diabetic medicine : a journal of the British Diabetic Association, 2015, Volume: 32, Issue:7

    Topics: Benzhydryl Compounds; Cohort Studies; Cost-Benefit Analysis; Diabetes Complications; Diabetes Mellitus, Type 2; Drug Resistance; Drug Therapy, Combination; Female; Glucosides; Health Care Costs; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Male; Metformin; Middle Aged; Overweight; Quality-Adjusted Life Years; Risk; Sodium-Glucose Transport Proteins; Sulfonylurea Compounds; United Kingdom; Weight Loss

2015
Empagliflozin as add-on to metformin in people with Type 2 diabetes.
    Diabetic medicine : a journal of the British Diabetic Association, 2015, Volume: 32, Issue:12

    Topics: Aged; Benzhydryl Compounds; Body Mass Index; Combined Modality Therapy; Diabetes Mellitus, Type 2; Diet, Diabetic; Dose-Response Relationship, Drug; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Exercise; Female; Glucosides; Humans; Hyperglycemia; Hypertension; Hypoglycemia; Hypoglycemic Agents; Male; Membrane Transport Modulators; Metformin; Middle Aged; Overweight; Sodium-Glucose Transporter 2 Inhibitors

2015
Effect of 24-week treatment with ipragliflozin on proinsulin/C-peptide ratio in Japanese patients with type 2 diabetes.
    Expert opinion on pharmacotherapy, 2017, Volume: 18, Issue:1

    Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucose; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin-Secreting Cells; Male; Middle Aged; Proinsulin; Prospective Studies; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes

2017
Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetes.
    Diabetes care, 2009, Volume: 32, Issue:4

    Topics: Adolescent; Adult; Aged; Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus, Type 2; Diuretics; Dose-Response Relationship, Drug; Female; Glucosides; Glycated Hemoglobin; Glycosuria; Humans; Hyperglycemia; Hypoglycemic Agents; Male; Metformin; Middle Aged; Placebos; Sodium-Glucose Transport Proteins; Weight Loss; Young Adult

2009
Effect of Ipragliflozin (ASP1941), a novel selective sodium-dependent glucose co-transporter 2 inhibitor, on urinary glucose excretion in healthy subjects.
    Clinical drug investigation, 2011, Dec-01, Volume: 31, Issue:12

    Topics: Adult; Blood Glucose; Blood Pressure Determination; Body Mass Index; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Female; Glucose; Glucosides; Glycosuria; Heart Rate; Humans; Hyperglycemia; Hypoglycemic Agents; Male; Middle Aged; Placebos; Sex Factors; Sodium-Glucose Transporter 2 Inhibitors; Symporters; Thiophenes; Young Adult

2011
Safety, tolerability, pharmacokinetics and pharmacodynamics following 4 weeks' treatment with empagliflozin once daily in patients with type 2 diabetes.
    Diabetes, obesity & metabolism, 2013, Volume: 15, Issue:7

    Topics: Administration, Oral; Adult; Aged; Benzhydryl Compounds; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Germany; Glucosides; Glycosuria; Humans; Hyperglycemia; Hypoglycemic Agents; Incidence; Male; Membrane Transport Modulators; Middle Aged; Polyuria; Sodium-Glucose Transporter 2 Inhibitors

2013

Other Studies

104 other study(ies) available for glucose, (beta-d)-isomer and Hyperglycemia, Postprandial

ArticleYear
Hyperglycemia and Some Aspects of Leukocyte Activation In Vitro.
    Bulletin of experimental biology and medicine, 2021, Volume: 170, Issue:6

    Topics: Diabetes Mellitus; Extracellular Traps; Humans; Hyperglycemia; Leukocytes; Luminescent Measurements; Neutrophils; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Zymosan

2021
The production of reactive oxygen species in TLR-stimulated granulocytes is not enhanced by hyperglycemia in diabetes.
    International immunopharmacology, 2013, Volume: 17, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Cells, Cultured; Concanavalin A; Diabetes Mellitus, Type 2; Female; Granulocytes; Humans; Hyperglycemia; Lipopolysaccharides; Male; Middle Aged; Mitogen-Activated Protein Kinases; NADPH Oxidases; Reactive Oxygen Species; Toll-Like Receptors; Zymosan

2013
Induction of innate immune response through TLR2 and dectin 1 prevents type 1 diabetes.
    Journal of immunology (Baltimore, Md. : 1950), 2008, Dec-15, Volume: 181, Issue:12

    Topics: Animals; Antigen-Presenting Cells; Cells, Cultured; Coculture Techniques; Crosses, Genetic; Cytokines; Diabetes Mellitus, Type 1; Female; Hyperglycemia; Hyperinsulinism; Immunity, Innate; Lectins, C-Type; Membrane Proteins; Mice; Mice, Inbred NOD; Mice, SCID; Nerve Tissue Proteins; Prediabetic State; Toll-Like Receptor 2; Zymosan

2008
Chronic hyperglycemia predisposes to exaggerated inflammatory response and leukocyte dysfunction in Akita mice.
    Journal of immunology (Baltimore, Md. : 1950), 2006, Nov-15, Volume: 177, Issue:10

    Topics: Acute Disease; Animals; Chemotaxis, Leukocyte; Chronic Disease; Cytokines; Female; Hyperglycemia; Inflammation; Leukocytes; Male; Mice; Mice, Mutant Strains; Neutrophils; Peritonitis; Point Mutation; Superoxides; Zymosan

2006
Activation of RAGE induces elevated O2- generation by mononuclear phagocytes in diabetes.
    Journal of leukocyte biology, 2007, Volume: 81, Issue:2

    Topics: Adult; Diabetes Mellitus; Female; Glucose; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Hyperglycemia; Male; Middle Aged; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Nerve Growth Factors; Receptor for Advanced Glycation End Products; Receptors, Immunologic; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Structure-Activity Relationship; Superoxides; Tetradecanoylphorbol Acetate; Zymosan

2007
Oxygen metabolism of phagocytosing human polymorphonuclear leucocytes in diabetes mellitus.
    Blut, 1984, Volume: 49, Issue:6

    Topics: Aged; Diabetes Mellitus; Female; Glucose; Humans; Hyperglycemia; Male; Neutrophils; Oxygen Consumption; Phagocytes; Phagocytosis; Superoxides; Zymosan

1984
Agonist-dependent failure of neutrophil function in diabetes correlates with extent of hyperglycemia.
    Journal of leukocyte biology, 2001, Volume: 70, Issue:3

    Topics: Adult; Blood Glucose; Calcimycin; Cells, Cultured; Cross-Sectional Studies; Diabetes Mellitus; Female; Humans; Hyperglycemia; Leukotriene B4; Lysosomes; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Zymosan

2001
In a Prediabetic Model, Empagliflozin Improves Hepatic Lipid Metabolism Independently of Obesity and before Onset of Hyperglycemia.
    International journal of molecular sciences, 2021, Oct-26, Volume: 22, Issue:21

    Topics: Animals; Benzhydryl Compounds; Cytochrome P-450 Enzyme System; Disease Models, Animal; Disease Progression; Glucosides; Hyperglycemia; Hyperlipoproteinemia Type IV; Inflammation Mediators; Insulin Resistance; Lipid Metabolism; Liver; Male; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; Prediabetic State; Rats; Rats, Mutant Strains; Rats, Wistar; Sodium-Glucose Transporter 2 Inhibitors

2021
Dapagliflozin attenuates high glucose-induced endothelial cell apoptosis and inflammation through AMPK/SIRT1 activation.
    Clinical and experimental pharmacology & physiology, 2022, Volume: 49, Issue:6

    Topics: AMP-Activated Protein Kinases; Anti-Inflammatory Agents; Apoptosis; Benzhydryl Compounds; Glucose; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Hyperglycemia; Inflammation; Interleukin-6; Oxidative Stress; Reactive Oxygen Species; Sirtuin 1; Tumor Necrosis Factor-alpha

2022
Novel cardioprotective mechanism for Empagliflozin in nondiabetic myocardial infarction with acute hyperglycemia.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 154

    Topics: Animals; Beclin-1; Benzhydryl Compounds; Glucosides; Hyperglycemia; Mice; Myocardial Infarction; Sodium-Glucose Transporter 2 Inhibitors

2022
Dapagliflozin (SGLT2-i) induced euglycaemic diabetic ketoacidosis.
    BMJ case reports, 2019, Sep-19, Volume: 12, Issue:9

    Topics: Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Ketoacidosis; Female; Glucosides; Humans; Hyperglycemia; Kidney Tubules, Proximal; Middle Aged; Sodium-Glucose Transporter 2 Inhibitors

2019
Ameliorative effect of polydatin on hyperglycemia and renal injury in streptozotocin-induced diabetic rats.
    Cellular and molecular biology (Noisy-le-Grand, France), 2019, Sep-30, Volume: 65, Issue:7

    Topics: 3T3-L1 Cells; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glucose Transporter Type 1; Glucose Transporter Type 4; Glucosides; HEK293 Cells; Humans; Hyperglycemia; Inflammation; Mice; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Stilbenes

2019
Empagliflozin attenuates transient cerebral ischemia/reperfusion injury in hyperglycemic rats via repressing oxidative-inflammatory-apoptotic pathway.
    Fundamental & clinical pharmacology, 2020, Volume: 34, Issue:5

    Topics: Animals; Apoptosis; Benzhydryl Compounds; Disease Models, Animal; Gliclazide; Glucosides; Hyperglycemia; Hypoglycemic Agents; Inflammation; Ischemic Attack, Transient; Male; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar

2020
Effect of dapagliflozin alone and in combination with insulin in a rat model of type 1 diabetes.
    The Journal of veterinary medical science, 2020, Apr-09, Volume: 82, Issue:4

    Topics: Animals; Antioxidants; Benzhydryl Compounds; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Glucosides; Hypercholesterolemia; Hyperglycemia; Hypertriglyceridemia; Hypoglycemic Agents; Insulin; Male; Rats, Sprague-Dawley; Sodium-Glucose Transporter 2 Inhibitors

2020
The insulin-sensitising properties of the ellagitannin geraniin and its metabolites from
    International journal of food sciences and nutrition, 2020, Volume: 71, Issue:8

    Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Biological Transport; Cell Differentiation; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Glucose; Glucosides; Hydrolyzable Tannins; Hyperglycemia; Insulin; Lipolysis; Mice; Obesity; Plant Extracts; Sapindaceae

2020
NLRP3 as Putative Marker of Ipilimumab-Induced Cardiotoxicity in the Presence of Hyperglycemia in Estrogen-Responsive and Triple-Negative Breast Cancer Cells.
    International journal of molecular sciences, 2020, Oct-21, Volume: 21, Issue:20

    Topics: Antineoplastic Agents, Immunological; Benzhydryl Compounds; Biomarkers, Pharmacological; Cardiotoxicity; Cell Line, Tumor; CTLA-4 Antigen; Female; Glucose; Glucosides; Humans; Hyperglycemia; Ipilimumab; Leukotriene B4; Myeloid Differentiation Factor 88; Myocytes, Cardiac; NLR Family, Pyrin Domain-Containing 3 Protein; Sodium-Glucose Transporter 2 Inhibitors; Transcription Factor RelA; Triple Negative Breast Neoplasms

2020
[Short-term Glucose Lowering Effects of Sodium-glucose Cotransporter 2 Inhibitors Confirmed by Flash Glucose Monitoring in Two Outpatients with Type 1 Diabetes].
    Journal of UOEH, 2020, Volume: 42, Issue:4

    Topics: Adult; Benzhydryl Compounds; Blood Glucose; Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 1; Female; Glucosides; Glycemic Control; Humans; Hyperglycemia; Male; Middle Aged; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Time Factors; Treatment Outcome

2020
Glomerular hyperfiltration with hyperglycemia in the spontaneously diabetic Torii (SDT) fatty rat, an obese type 2 diabetic model.
    Physiological research, 2021, 03-17, Volume: 70, Issue:1

    Topics: Animals; Benzhydryl Compounds; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Glomerular Filtration Rate; Glucosides; Hyperglycemia; Male; Obesity; Rats; Rats, Sprague-Dawley; Sodium-Glucose Transporter 2 Inhibitors

2021
Glucosyl Hesperidin Has an Anti-diabetic Effect in High-Fat Diet-Induced Obese Mice.
    Biological & pharmaceutical bulletin, 2021, Volume: 44, Issue:3

    Topics: 3T3-L1 Cells; Adipose Tissue; Animals; Chemokine CCL2; Coculture Techniques; Diet, High-Fat; Disease Models, Animal; Glucosides; Hesperidin; Hyperglycemia; Hypoglycemic Agents; Macrophages; Male; Mice; Mice, Inbred C57BL; Obesity; RAW 264.7 Cells

2021
Empagliflozin ameliorates symptoms of diabetes and renal tubular dysfunction in a rat model of diabetes with enlarged kidney (DEK).
    PloS one, 2021, Volume: 16, Issue:5

    Topics: Animals; Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucosides; Hyperglycemia; Kidney; Kidney Diseases; Male; Rats; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors

2021
Empagliflozin nanoparticles attenuates type2 diabetes induced cognitive impairment via oxidative stress and inflammatory pathway in high fructose diet induced hyperglycemic mice.
    Neurochemistry international, 2021, Volume: 150

    Topics: Animals; Benzhydryl Compounds; Blood Glucose; Cognitive Dysfunction; Diabetes Mellitus, Type 2; Fructose; Glucosides; Hyperglycemia; Inflammation Mediators; Mice; Mice, Inbred C57BL; Nanoparticles; Oxidative Stress; Sodium-Glucose Transporter 2 Inhibitors

2021
Insight into anti-diabetic effect of low dose of stevioside.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 90

    Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diterpenes, Kaurane; Glucose Tolerance Test; Glucosides; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Mice; Phytotherapy; Plant Extracts; Stevia

2017
Empagliflozin/linagliptin single-pill combination therapy for patients with type 2 diabetes mellitus.
    Expert opinion on pharmacotherapy, 2017, Volume: 18, Issue:6

    Topics: Adult; Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Combinations; Glucosides; Humans; Hyperglycemia; Hypoglycemic Agents; Linagliptin; Metformin; Randomized Controlled Trials as Topic; Sodium-Glucose Transporter 2 Inhibitors

2017
A comparison of effects of DPP-4 inhibitor and SGLT2 inhibitor on lipid profile in patients with type 2 diabetes.
    Lipids in health and disease, 2017, Apr-13, Volume: 16, Issue:1

    Topics: Benzhydryl Compounds; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Cardiomyopathies; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Female; Follow-Up Studies; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Hyperlipidemias; Linagliptin; Male; Membrane Transport Modulators; Middle Aged; Piperidones; Pyrimidines; Republic of Korea; Retrospective Studies; Risk Factors; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors

2017
Antioxidant activity of phenolic compounds from extracts of Eucalyptus globulus and Melaleuca styphelioides and their protective role on D-glucose-induced hyperglycemic stress and oxalate stress in NRK-49Fcells.
    Natural product research, 2018, Volume: 32, Issue:11

    Topics: Animals; Antioxidants; Cell Line; Enzymes; Eucalyptus; Gallic Acid; Glucose; Glucosides; Glycosides; Humans; Hydrolyzable Tannins; Hyperglycemia; Lipid Peroxidation; Melaleuca; Oxalates; Phenols; Plant Extracts; Protective Agents

2018
Cardiovascular Disease and Type 2 Diabetes: Has the Dawn of a New Era Arrived?
    Diabetes care, 2017, Volume: 40, Issue:7

    Topics: Animals; Benzhydryl Compounds; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Glucagon-Like Peptides; Glucosides; Humans; Hyperglycemia; Hypoglycemic Agents; Liraglutide; Pioglitazone; Randomized Controlled Trials as Topic; Risk Factors; Thiazolidinediones; Treatment Outcome

2017
Does SGLT2 inhibition with dapagliflozin overcome individual therapy resistance to RAAS inhibition?
    Diabetes, obesity & metabolism, 2018, Volume: 20, Issue:1

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Benzhydryl Compounds; Biomarkers; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Drug Resistance; Female; Glucosides; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Kidney; Male; Membrane Transport Modulators; Middle Aged; Randomized Controlled Trials as Topic; Renal Insufficiency; Renin-Angiotensin System; Retrospective Studies; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors

2018
Dapagliflozin is associated with lower risk of cardiovascular events and all-cause mortality in people with type 2 diabetes (CVD-REAL Nordic) when compared with dipeptidyl peptidase-4 inhibitor therapy: A multinational observational study.
    Diabetes, obesity & metabolism, 2018, Volume: 20, Issue:2

    Topics: Aged; Benzhydryl Compounds; Cardiovascular Diseases; Denmark; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Cardiomyopathies; Dipeptidyl-Peptidase IV Inhibitors; Female; Follow-Up Studies; Glucosides; Humans; Hyperglycemia; Hypoglycemia; Incidence; Kaplan-Meier Estimate; Male; Membrane Transport Modulators; Middle Aged; Norway; Proportional Hazards Models; Risk; Sodium-Glucose Transporter 2; Sweden

2018
A new polyacetylene glucoside from Vernonia scorpioides and its potential antihyperglycemic effect.
    Chemico-biological interactions, 2018, Jan-05, Volume: 279

    Topics: Animals; Blood Glucose; Glucose; Glucose Tolerance Test; Glucosides; Hyperglycemia; Hypoglycemic Agents; Male; Models, Molecular; Molecular Structure; Polyynes; Rats; Rats, Wistar; Vernonia

2018
Euglycemic Diabetic Ketoacidosis Secondary to Dapagliflozin Use: A Case Report.
    The Journal of emergency medicine, 2018, Volume: 54, Issue:1

    Topics: Abdominal Pain; Anorexia; Benzhydryl Compounds; Diabetes Mellitus, Type 2; Diabetic Ketoacidosis; Glucosides; Humans; Hyperglycemia; Male; Middle Aged; Sodium-Glucose Transporter 2; Vomiting

2018
Insulin dependent and independent normalization of blood glucose levels reduces the enhanced rewarding effects of nicotine in a rodent model of diabetes.
    Behavioural brain research, 2018, 10-01, Volume: 351

    Topics: Animals; Benzhydryl Compounds; Blood Glucose; Conditioning, Psychological; Diabetes Mellitus, Experimental; Female; Glucosides; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Nicotine; Nicotinic Agonists; Reward

2018
Renoprotection of dapagliflozin in human renal proximal tubular cells via the inhibition of the high mobility group box 1‑receptor for advanced glycation end products‑nuclear factor‑κB signaling pathway.
    Molecular medicine reports, 2018, Volume: 18, Issue:4

    Topics: Benzhydryl Compounds; Cell Line, Tumor; Glucosides; HMGB1 Protein; Humans; Hyperglycemia; Hypoglycemic Agents; Inflammation; Kidney Tubules, Proximal; NF-kappa B; Oxidative Stress; Protective Agents; Receptor for Advanced Glycation End Products; Signal Transduction; Sodium-Glucose Transporter 2 Inhibitors

2018
Fibroblast growth factor 21 regulates glucose metabolism in part by reducing renal glucose reabsorption.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 108

    Topics: Animals; Blood Glucose; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Fibroblast Growth Factors; Glucose; Glucosides; Homeostasis; Humans; Hyperglycemia; Insulin; Insulin Resistance; Kidney; Male; Mice; Mice, Inbred C57BL; PPAR delta; Sodium-Glucose Transporter 2

2018
Chronic social stress-induced hyperglycemia in mice couples individual stress susceptibility to impaired spatial memory.
    Proceedings of the National Academy of Sciences of the United States of America, 2018, 10-23, Volume: 115, Issue:43

    Topics: Animals; Behavior, Animal; Benzhydryl Compounds; Brain; Chronic Disease; Glucose; Glucosides; Hyperglycemia; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Social Desirability; Spatial Memory; Stress, Psychological

2018
In vitro and in vivo hypoglycemic effects of cyanidin 3-caffeoyl-p-hydroxybenzoylsophoroside-5-glucoside, an anthocyanin isolated from purple-fleshed sweet potato.
    Food chemistry, 2019, Jan-30, Volume: 272

    Topics: Animals; Anthocyanins; Antioxidants; Blood Glucose; Chromatography, High Pressure Liquid; Diet, High-Fat; Glucosides; Hep G2 Cells; Humans; Hyperglycemia; Hypoglycemic Agents; Ipomoea batatas; Male; Mice; Mice, Inbred C57BL; Plant Extracts; Spectrometry, Mass, Electrospray Ionization

2019
Tetrahydroxy stilbene glucoside protected against diabetes-induced osteoporosis in mice with streptozotocin-induced hyperglycemia.
    Phytotherapy research : PTR, 2019, Volume: 33, Issue:2

    Topics: Animals; Bone and Bones; Diabetes Mellitus, Experimental; Femur; Glucosides; Hyperglycemia; Male; Mice; Mice, Inbred C57BL; Osteoblasts; Osteoclasts; Osteogenesis; Osteoporosis; Renin-Angiotensin System; Stilbenes; Streptozocin; Tartrate-Resistant Acid Phosphatase

2019
Action of corilagin on hyperglycemia, hyperlipidemia and oxidative stress in streptozotocin-induced diabetic rats.
    Chemico-biological interactions, 2019, Feb-01, Volume: 299

    Topics: Animals; Blood Glucose; Body Weight; Catalase; Diabetes Mellitus, Experimental; Glucosides; Glutathione; Glycated Hemoglobin; Hydrolyzable Tannins; Hyperglycemia; Hyperlipidemias; Insulin; Lipids; Male; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase

2019
Salidroside-Pretreated Mesenchymal Stem Cells Enhance Diabetic Wound Healing by Promoting Paracrine Function and Survival of Mesenchymal Stem Cells Under Hyperglycemia.
    Stem cells translational medicine, 2019, Volume: 8, Issue:4

    Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Glucosides; Hyperglycemia; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Paracrine Communication; Phenols; Survival Rate; Wound Healing

2019
Polyphenols of Myrica faya inhibit key enzymes linked to type II diabetes and obesity and formation of advanced glycation end-products (in vitro): Potential role in the prevention of diabetic complications.
    Food research international (Ottawa, Ont.), 2019, Volume: 116

    Topics: Aldehyde Reductase; alpha-Amylases; alpha-Glucosidases; Anthocyanins; Anti-Obesity Agents; Antioxidants; Azores; Diabetes Complications; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Flavonoids; Glucosides; Glycation End Products, Advanced; Humans; Hyperglycemia; Hypoglycemic Agents; Lipase; Myrica; Obesity; Phytochemicals; Plant Extracts; Polyphenols; Portugal; Serum Albumin, Bovine

2019
Resveratroloside Alleviates Postprandial Hyperglycemia in Diabetic Mice by Competitively Inhibiting α-Glucosidase.
    Journal of agricultural and food chemistry, 2019, Mar-13, Volume: 67, Issue:10

    Topics: alpha-Glucosidases; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucosides; Glycoside Hydrolase Inhibitors; Humans; Hyperglycemia; Male; Mice; Molecular Docking Simulation; Stilbenes

2019
Hyperglycemia induces skeletal muscle atrophy via a WWP1/KLF15 axis.
    JCI insight, 2019, 02-21, Volume: 4, Issue:4

    Topics: Animals; Benzhydryl Compounds; Chlorocebus aethiops; COS Cells; Diabetes Mellitus, Experimental; Down-Regulation; Female; Gene Expression Profiling; Glucosides; HEK293 Cells; Humans; Hyperglycemia; Kruppel-Like Transcription Factors; Male; Mice; Mice, Knockout; Muscle, Skeletal; Muscular Atrophy; Proteolysis; Signal Transduction; Sodium-Glucose Transporter 2 Inhibitors; Streptozocin; Ubiquitin-Protein Ligases; Up-Regulation

2019
Macula Densa SGLT1-NOS1-Tubuloglomerular Feedback Pathway, a New Mechanism for Glomerular Hyperfiltration during Hyperglycemia.
    Journal of the American Society of Nephrology : JASN, 2019, Volume: 30, Issue:4

    Topics: Animals; Feedback, Physiological; Glomerular Filtration Rate; Glucose; Glucosides; Humans; Hyperglycemia; Inulin; Kidney Glomerulus; Kidney Tubules, Distal; Male; Mice; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type I; Phosphorylation; Pyrazoles; Signal Transduction; Sodium-Glucose Transporter 1

2019
A Protective Role of Paeoniflorin in Fluctuant Hyperglycemia-Induced Vascular Endothelial Injuries through Antioxidative and Anti-Inflammatory Effects and Reduction of PKC
    Oxidative medicine and cellular longevity, 2019, Volume: 2019

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Hyperglycemia; Inflammation; Male; Monoterpenes; Oxidative Stress; Protective Agents; Protein Kinase C beta; Rats, Sprague-Dawley; Vascular System Injuries

2019
Effects of SGLT2 selective inhibitor ipragliflozin on hyperglycemia, hyperlipidemia, hepatic steatosis, oxidative stress, inflammation, and obesity in type 2 diabetic mice.
    European journal of pharmacology, 2013, Sep-05, Volume: 715, Issue:1-3

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Diet, High-Fat; Fatty Liver; Glucose Tolerance Test; Glucosides; Glycosuria; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; Inflammation; Insulin; Insulin Resistance; Insulin Secretion; Male; Mice; Obesity; Oxidative Stress; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes

2013
SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice.
    American journal of physiology. Renal physiology, 2014, Volume: 306, Issue:2

    Topics: Adipocytes; Albuminuria; Animals; Benzhydryl Compounds; Biomarkers; Blood Glucose; Blood Pressure; Blotting, Western; Diabetes Mellitus; Diabetic Nephropathies; Drinking; Eating; Glomerular Filtration Rate; Glucosides; Heart Rate; Hyperglycemia; Inflammation; Kidney; Kidney Glomerulus; Mice; Mice, Inbred Strains; Real-Time Polymerase Chain Reaction; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors

2014
Glucosidase inhibitory activity and antioxidant activity of flavonoid compound and triterpenoid compound from Agrimonia Pilosa Ledeb.
    BMC complementary and alternative medicine, 2014, Jan-10, Volume: 14

    Topics: Agrimonia; alpha-Glucosidases; Antioxidants; beta Carotene; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Flavonoids; Free Radical Scavengers; Glucosides; Glycoside Hydrolase Inhibitors; Hyperglycemia; Kinetics; Lipid Peroxidation; Oxidation-Reduction; Oxidative Stress; Plant Extracts; Postprandial Period; Quercetin; Triterpenes

2014
Effects of sodium-glucose cotransporter 2 selective inhibitor ipragliflozin on hyperglycaemia, oxidative stress, inflammation and liver injury in streptozotocin-induced type 1 diabetic rats.
    The Journal of pharmacy and pharmacology, 2014, Volume: 66, Issue:7

    Topics: Albuminuria; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Fatty Liver; Glomerular Filtration Rate; Glucose Intolerance; Glucosides; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; Inflammation; Kidney; Liver; Male; Oxidative Stress; Rats, Sprague-Dawley; Sodium-Glucose Transporter 2 Inhibitors; Streptozocin; Thiophenes

2014
Glucotoxicity targets hepatic glucokinase in Zucker diabetic fatty rats, a model of type 2 diabetes associated with obesity.
    American journal of physiology. Endocrinology and metabolism, 2014, Jun-01, Volume: 306, Issue:11

    Topics: Animals; Body Weight; Canagliflozin; Diabetes Mellitus, Type 2; Eating; Glucagon; Glucokinase; Glucose; Glucose Clamp Technique; Glucosides; Hyperglycemia; Hyperinsulinism; Immunohistochemistry; Liver; Male; Obesity; Organ Size; Oxygen Consumption; Rats; Rats, Zucker; RNA, Messenger; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes

2014
SGLT-2 inhibitors as second-line therapy in type 2 diabetes.
    The lancet. Diabetes & endocrinology, 2014, Volume: 2, Issue:9

    Topics: Benzhydryl Compounds; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Glucosides; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Metformin; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Treatment Outcome

2014
Metformin supports the antidiabetic effect of a sodium glucose cotransporter 2 inhibitor by suppressing endogenous glucose production in diabetic mice.
    Diabetes, 2015, Volume: 64, Issue:1

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Therapy, Combination; Glucose; Glucose Clamp Technique; Glucosides; Glycated Hemoglobin; Hyperglycemia; Hypoglycemic Agents; Metformin; Mice, Knockout; Mice, Obese; Obesity; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors

2015
Analysis of the effect of canagliflozin on renal glucose reabsorption and progression of hyperglycemia in zucker diabetic Fatty rats.
    The Journal of pharmacology and experimental therapeutics, 2014, Volume: 351, Issue:2

    Topics: Animals; Blood Glucose; Canagliflozin; Diabetes Mellitus, Experimental; Dogs; Glucose; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Kidney; Mice; Rats; Rats, Zucker; Sodium-Glucose Transporter 2; Thiophenes

2014
Ameliorated pancreatic β cell dysfunction in type 2 diabetic patients treated with a sodium-glucose cotransporter 2 inhibitor ipragliflozin.
    Endocrine journal, 2015, Volume: 62, Issue:1

    Topics: Adult; Algorithms; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucose Tolerance Test; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Japan; Male; Middle Aged; Pilot Projects; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes

2015
Exploiting the therapeutic potential of 8-β-d-glucopyranosylgenistein: synthesis, antidiabetic activity, and molecular interaction with islet amyloid polypeptide and amyloid β-peptide (1-42).
    Journal of medicinal chemistry, 2014, Nov-26, Volume: 57, Issue:22

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Diabetes Mellitus, Experimental; Drug Design; Epitopes; Genista; Genistein; Glucosides; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Islet Amyloid Polypeptide; Magnetic Resonance Spectroscopy; Microscopy, Atomic Force; Microscopy, Fluorescence; Oxygen; Protein Binding; Protein Conformation; Protein Kinase Inhibitors; Rats; Rats, Wistar; Streptozocin; Thiazoles

2014
Glycosuria-mediated urinary uric acid excretion in patients with uncomplicated type 1 diabetes mellitus.
    American journal of physiology. Renal physiology, 2015, Jan-15, Volume: 308, Issue:2

    Topics: Adult; Benzhydryl Compounds; Case-Control Studies; Diabetes Mellitus, Type 1; Female; Glucosides; Glycosuria; Humans; Hyperglycemia; Male; Sodium-Glucose Transporter 2 Inhibitors; Uric Acid; Young Adult

2015
[Empagliflozin - the new representative of SGLT2 transporter inhibitors for the treatment of patients with diabetes 2 type].
    Vnitrni lekarstvi, 2015, Volume: 61, Issue:2

    Topics: Benzhydryl Compounds; Blood Glucose; Blood Pressure; Czech Republic; Diabetes Mellitus, Type 2; Drug Approval; European Union; Glucosides; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Metformin; Sodium-Glucose Transporter 2 Inhibitors

2015
The cardiovascular effects of salidroside in the Goto-Kakizaki diabetic rat model.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2015, Volume: 66, Issue:2

    Topics: Animals; Aorta; Blood Pressure; Cardiotonic Agents; Cardiovascular Diseases; Cardiovascular System; Diabetes Mellitus, Type 2; Endothelium, Vascular; Glucose Intolerance; Glucosides; Guanylate Cyclase; Heart Rate; Hyperglycemia; Hypertension; Male; Myocytes, Smooth Muscle; Nitric Oxide Synthase Type III; Phenols; Rats; Rats, Inbred WKY; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vasodilation

2015
Polydatin Restores Endothelium-Dependent Relaxation in Rat Aorta Rings Impaired by High Glucose: A Novel Insight into the PPARβ-NO Signaling Pathway.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Animals; Aorta, Thoracic; Endothelial Cells; Endothelium; Enzyme Activation; Fallopia japonica; Female; Glucose; Glucosides; Hyperglycemia; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Plant Preparations; PPAR-beta; Rats; Rats, Sprague-Dawley; Signal Transduction; Stilbenes; Vasodilation; Vasodilator Agents

2015
Treatment satisfaction in type 2 diabetes patients taking empagliflozin compared with patients taking glimepiride.
    Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2016, Volume: 25, Issue:5

    Topics: Adult; Benzhydryl Compounds; Clinical Protocols; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Male; Metformin; Middle Aged; Personal Satisfaction; Quality of Life; Sulfonylurea Compounds; Treatment Outcome

2016
Amelioration of Hyperglycemia with a Sodium-Glucose Cotransporter 2 Inhibitor Prevents Macrophage-Driven Atherosclerosis through Macrophage Foam Cell Formation Suppression in Type 1 and Type 2 Diabetic Mice.
    PloS one, 2015, Volume: 10, Issue:11

    Topics: Animals; Atherosclerosis; Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Foam Cells; Gene Expression; Glucose Tolerance Test; Glucosides; Hyperglycemia; Hypoglycemic Agents; Macrophages, Peritoneal; Male; Mice; Mice, Knockout; Sodium-Glucose Transporter 2 Inhibitors

2015
Hyperglycemia and Anthocyanin Inhibit Quercetin Metabolism in HepG2 Cells.
    Journal of medicinal food, 2016, Volume: 19, Issue:2

    Topics: Anthocyanins; Antioxidants; Catalase; Chromatography, High Pressure Liquid; Glucosides; Hep G2 Cells; Humans; Hyperglycemia; Oxidative Stress; Quercetin; Reactive Oxygen Species; Superoxide Dismutase

2016
Effect of ipragliflozin, an SGLT2 inhibitor, on progression of diabetic microvascular complications in spontaneously diabetic Torii fatty rats.
    Life sciences, 2016, Feb-15, Volume: 147

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Disease Progression; Glucosides; Hyperglycemia; Hypoglycemic Agents; Male; Rats; Rats, Sprague-Dawley; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes

2016
Salidroside improves glucose homeostasis in obese mice by repressing inflammation in white adipose tissues and improving leptin sensitivity in hypothalamus.
    Scientific reports, 2016, 05-05, Volume: 6

    Topics: Adipose Tissue, White; Animals; Body Weight; Eating; Epididymis; Glucose-6-Phosphatase; Glucosides; Hyperglycemia; Hypothalamus; Inflammation; Leptin; Liver; Male; Mice; Mice, Obese; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phenols; Triglycerides

2016
[Efficacy of Ipragliflozin in Patients with Steroid-Induced Hyperglycemia during Cancer Chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:5

    Topics: Antiemetics; Blood Glucose; Chemoradiotherapy; Dexamethasone; Esophageal Neoplasms; Glucosides; Humans; Hyperglycemia; Male; Middle Aged; Neoplasm Staging; Thiophenes

2016
Sodium-Glucose Cotransporter 2 Inhibitor and a Low Carbohydrate Diet Affect Gluconeogenesis and Glycogen Content Differently in the Kidney and the Liver of Non-Diabetic Mice.
    PloS one, 2016, Volume: 11, Issue:6

    Topics: Animals; Body Weight; Cyclic AMP Response Element-Binding Protein; Diabetes Mellitus, Experimental; Diet, Carbohydrate-Restricted; Energy Intake; Fatty Acid Synthases; Forkhead Box Protein O1; Gluconeogenesis; Glucose Tolerance Test; Glucosides; Glycogen; Hyperglycemia; Insulin Resistance; Kidney; Lipid Metabolism; Liver; Male; Mice, Inbred C57BL; Obesity; RNA, Messenger; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Triglycerides; Up-Regulation

2016
Secoisolariciresinol diglucoside rich extract of L. usitatissimum prevents diabetic colon cancer through inhibition of CDK4.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 83

    Topics: Animals; Biomarkers, Tumor; Butylene Glycols; Cell Proliferation; Colonic Neoplasms; Cyclin-Dependent Kinase 4; Cytokines; Diabetes Mellitus, Type 2; Female; Flax; Gene Expression Regulation, Neoplastic; Glucose Tolerance Test; Glucosides; Hyperglycemia; Inflammation Mediators; Male; Phytochemicals; Plant Extracts; Proliferating Cell Nuclear Antigen; Rats, Sprague-Dawley; RNA, Messenger

2016
Procyanidin Promotes Translocation of Glucose Transporter 4 in Muscle of Mice through Activation of Insulin and AMPK Signaling Pathways.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: AMP-Activated Protein Kinases; Animals; Anthocyanins; Biflavonoids; Catechin; Disease Models, Animal; Glucose; Glucose Transporter Type 4; Glucosides; Humans; Hyperglycemia; Insulin; Mice; Muscle, Skeletal; Proanthocyanidins; Signal Transduction

2016
Effect of Sodium-Glucose Co-Transporter 2 Inhibitor, Dapagliflozin, on Renal Renin-Angiotensin System in an Animal Model of Type 2 Diabetes.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Aldosterone; Animals; Benzhydryl Compounds; Chymosin; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Glucosides; Hyperglycemia; Kidney; Lipid Peroxidation; Male; Rats, Inbred OLETF; Renin-Angiotensin System; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors

2016
Amelioration of fatty liver index in patients with type 2 diabetes on ipragliflozin: an association with glucose-lowering effects.
    Endocrine journal, 2017, Mar-31, Volume: 64, Issue:3

    Topics: Adiposity; Adult; Diabetes Mellitus, Type 2; Female; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Japan; Lipotropic Agents; Liver; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Prospective Studies; Severity of Illness Index; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes

2017
The Sodium-Glucose Cotransporter 2 Inhibitor Dapagliflozin Prevents Cardiomyopathy in a Diabetic Lipodystrophic Mouse Model.
    Diabetes, 2017, Volume: 66, Issue:4

    Topics: Animals; Benzhydryl Compounds; Blood Glucose; Cardiomyopathy, Hypertrophic; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Disease Models, Animal; Echocardiography; Fluorodeoxyglucose F18; Glucosides; GTP-Binding Protein gamma Subunits; Heart; Heterotrimeric GTP-Binding Proteins; Hyperglycemia; Hypoglycemic Agents; Lipodystrophy; Magnetic Resonance Imaging; Mice; Mice, Knockout; Myocardium; Pioglitazone; Positron-Emission Tomography; Radiopharmaceuticals; Sodium-Glucose Transporter 2 Inhibitors; Thiazolidinediones; Ventricular Dysfunction, Left; Ventricular Function

2017
Dapagliflozin improves insulin resistance and glucose intolerance in a novel transgenic rat model of chronic glucose overproduction and glucose toxicity.
    Diabetes, obesity & metabolism, 2017, Volume: 19, Issue:8

    Topics: Adipose Tissue, White; Adiposity; Animals; Benzhydryl Compounds; Cell Size; Gene Expression Regulation; Glucose Clamp Technique; Glucose Intolerance; Glucose Transporter Type 4; Glucosides; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Membrane Transport Modulators; Muscle, Skeletal; Phosphoenolpyruvate Carboxykinase (GTP); Rats, Transgenic; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Weight Gain

2017
Efficacy and safety of dapagliflozin in patients with type 2 diabetes and concomitant heart failure.
    Journal of diabetes and its complications, 2017, Volume: 31, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Benzhydryl Compounds; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Diuretics, Osmotic; Female; Glucosides; Glycated Hemoglobin; Heart Failure; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Longitudinal Studies; Male; Membrane Transport Modulators; Middle Aged; Randomized Controlled Trials as Topic; Risk Factors; Secondary Prevention; Sodium-Glucose Transport Proteins

2017
Empa's New Clothes: The Untold Story of the Empa-Reg Outcome Trial.
    Diabetes technology & therapeutics, 2017, Volume: 19, Issue:6

    Topics: Benzhydryl Compounds; Cardiovascular Diseases; Controlled Clinical Trials as Topic; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Cardiomyopathies; Drug Approval; Glucosides; Humans; Hyperglycemia; Hypoglycemic Agents; Mortality; Multicenter Studies as Topic; Survival Analysis

2017
Tetrahydroxystilbene glucoside ameliorates diabetic nephropathy in rats: involvement of SIRT1 and TGF-β1 pathway.
    European journal of pharmacology, 2010, Dec-15, Volume: 649, Issue:1-3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biomarkers; Cell Line; Cyclooxygenase 2; Diabetic Nephropathies; Dose-Response Relationship, Drug; Glucosides; Histone Deacetylase Inhibitors; Hyperglycemia; Kidney Cortex; Male; Mesangial Cells; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Signal Transduction; Sirtuin 1; Stilbenes; Transforming Growth Factor beta1

2010
The novel sodium glucose transporter 2 inhibitor dapagliflozin sustains pancreatic function and preserves islet morphology in obese, diabetic rats.
    Diabetes, obesity & metabolism, 2010, Volume: 12, Issue:11

    Topics: Animals; Benzhydryl Compounds; Diabetes Mellitus, Type 2; Female; Glucosides; Hyperglycemia; Islets of Langerhans; Obesity; Pancreas; Rats; Rats, Zucker; Sodium-Glucose Transporter 2 Inhibitors

2010
Discovery of novel N-β-D-xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes.
    Journal of medicinal chemistry, 2011, Jan-13, Volume: 54, Issue:1

    Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Glucosides; Humans; Hyperglycemia; Hypoglycemic Agents; Indoles; Male; Mice; Mice, Inbred ICR; Rats; Rats, Sprague-Dawley; Sodium-Glucose Transporter 2 Inhibitors; Structure-Activity Relationship; Xylose

2011
Hypoglycaemic action of stevioside and а barley and brewer's yeast based preparation in the experimental model on mice.
    Bosnian journal of basic medical sciences, 2011, Volume: 11, Issue:1

    Topics: Alloxan; Animals; Blood Glucose; Chromium; Diabetes Mellitus, Experimental; Disease Models, Animal; Diterpenes, Kaurane; Epinephrine; Fasting; Female; Glucose; Glucosides; Hordeum; Hyperglycemia; Hypoglycemic Agents; Male; Mice; Mice, Inbred Strains; Plant Extracts; Saccharomyces cerevisiae

2011
The anthocyanin cyanidin-3-O-β-glucoside, a flavonoid, increases hepatic glutathione synthesis and protects hepatocytes against reactive oxygen species during hyperglycemia: Involvement of a cAMP-PKA-dependent signaling pathway.
    Free radical biology & medicine, 2012, Jan-15, Volume: 52, Issue:2

    Topics: Animals; Anthocyanins; Antioxidants; Apoptosis; Cell Survival; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cytoprotection; Enzyme Activation; fas Receptor; Fatty Liver; Gene Expression; Glucosides; Glutamate-Cysteine Ligase; Glutathione; Hep G2 Cells; Hepatocytes; Humans; Hyperglycemia; Liver; Male; MAP Kinase Kinase 4; Mice; Mice, Obese; Oxidative Stress; Protein Binding; Reactive Oxygen Species; Signal Transduction; Thiobarbituric Acid Reactive Substances; Up-Regulation

2012
Cyanidin-3-glucoside-rich extract from Chinese bayberry fruit protects pancreatic β cells and ameliorates hyperglycemia in streptozotocin-induced diabetic mice.
    Journal of medicinal food, 2012, Volume: 15, Issue:3

    Topics: Animals; Anthocyanins; Antioxidants; Cell Line; Cell Survival; China; Diabetes Mellitus, Experimental; Fruit; Gene Expression Regulation; Glucosides; Homeodomain Proteins; Hyperglycemia; Hypoglycemic Agents; Insulin-Like Growth Factor II; Insulin-Secreting Cells; Male; Mice; Mice, Inbred ICR; Myrica; Plant Extracts; Random Allocation; Rats; Reactive Oxygen Species; RNA, Messenger; Trans-Activators

2012
Effect of canagliflozin on renal threshold for glucose, glycemia, and body weight in normal and diabetic animal models.
    PloS one, 2012, Volume: 7, Issue:2

    Topics: Animals; Blood Glucose; Body Weight; Canagliflozin; Cells, Cultured; CHO Cells; Cricetinae; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Glucosides; Humans; Hyperglycemia; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Muscle, Skeletal; Rats; Rats, Zucker; Sodium-Glucose Transport Proteins; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Weight Gain

2012
Tofogliflozin, a potent and highly specific sodium/glucose cotransporter 2 inhibitor, improves glycemic control in diabetic rats and mice.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 341, Issue:3

    Topics: Animals; Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glucose Intolerance; Glucose Tolerance Test; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Kidney; Male; Mice; Mice, Inbred Strains; Rats; Rats, Sprague-Dawley; Rats, Zucker; Sodium-Glucose Transporter 2 Inhibitors

2012
KGA-2727, a novel selective inhibitor of a high-affinity sodium glucose cotransporter (SGLT1), exhibits antidiabetic efficacy in rodent models.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 342, Issue:2

    Topics: Animals; Diabetes Mellitus, Experimental; Glucagon-Like Peptide 1; Glucose; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Intestinal Absorption; Intestine, Small; Islets of Langerhans; Male; Pyrazoles; Rats; Rats, Wistar; Rats, Zucker; Sodium-Glucose Transporter 1

2012
Cyanidin-3-O-β-glucoside, a typical anthocyanin, exhibits antilipolytic effects in 3T3-L1 adipocytes during hyperglycemia: involvement of FoxO1-mediated transcription of adipose triglyceride lipase.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2012, Volume: 50, Issue:9

    Topics: 3T3-L1 Cells; Acylation; Adenylate Kinase; Adipocytes; Animals; Anthocyanins; Base Sequence; DNA Primers; Enzyme Activation; Forkhead Box Protein O1; Forkhead Transcription Factors; Glucose; Glucosides; Hyperglycemia; Lipase; Lipolysis; Mice; Polymerase Chain Reaction; Transcription, Genetic

2012
Anti-hyperglycemic effect of chebulagic acid from the fruits of Terminalia chebula Retz.
    International journal of molecular sciences, 2012, Volume: 13, Issue:5

    Topics: Administration, Oral; alpha-Glucosidases; Animals; Benzopyrans; Caco-2 Cells; Down-Regulation; Drug Evaluation, Preclinical; Fruit; Glucosides; Humans; Hyperglycemia; Hypoglycemic Agents; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Terminalia

2012
Structure-activity relationship studies of 4-benzyl-1H-pyrazol-3-yl β-d-glucopyranoside derivatives as potent and selective sodium glucose co-transporter 1 (SGLT1) inhibitors with therapeutic activity on postprandial hyperglycemia.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Animals; Blood Glucose; Crystallography, X-Ray; Diabetes Mellitus, Experimental; Glucosides; Humans; Hyperglycemia; Hypoglycemic Agents; Molecular Conformation; Rats; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Structure-Activity Relationship

2012
Selective SGLT2 inhibition by tofogliflozin reduces renal glucose reabsorption under hyperglycemic but not under hypo- or euglycemic conditions in rats.
    American journal of physiology. Endocrinology and metabolism, 2013, Feb-15, Volume: 304, Issue:4

    Topics: Absorption; Animals; Benzhydryl Compounds; Blood Glucose; Creatinine; Dose-Response Relationship, Drug; Gluconeogenesis; Glucosides; Glycosuria; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Kidney; Male; Phlorhizin; Rats; Rats, Wistar; Sodium Channel Blockers; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors

2013
Acarviosine-simmondsin, a novel compound obtained from acarviosine-glucose and simmondsin by Thermus maltogenic amylase and its in vivo effect on food intake and hyperglycemia.
    Bioscience, biotechnology, and biochemistry, 2003, Volume: 67, Issue:3

    Topics: Acetonitriles; alpha-Amylases; Amino Sugars; Animals; Anti-Obesity Agents; Blood Glucose; Body Weight; Carbohydrate Sequence; Cyclohexanes; Eating; Glucose; Glucosides; Glycoside Hydrolase Inhibitors; Glycoside Hydrolases; Glycosylation; Hydrolysis; Hyperglycemia; Hypoglycemic Agents; Molecular Sequence Data; Postprandial Period; Rats; Rats, Sprague-Dawley; Swine; Thermus

2003
Dietary cyanidin 3-O-beta-D-glucoside-rich purple corn color prevents obesity and ameliorates hyperglycemia in mice.
    The Journal of nutrition, 2003, Volume: 133, Issue:7

    Topics: Adipose Tissue; Animals; Anthocyanins; Base Sequence; Body Weight; CCAAT-Enhancer-Binding Proteins; Diet; DNA Primers; DNA-Binding Proteins; Energy Intake; Glucosides; Hyperglycemia; Insulin Resistance; Lipids; Liver; Male; Mice; Mice, Inbred BALB C; Obesity; Organ Size; Sterol Regulatory Element Binding Protein 1; Transcription Factors

2003
Long-term treatment with the Na+-glucose cotransporter inhibitor T-1095 causes sustained improvement in hyperglycemia and prevents diabetic neuropathy in Goto-Kakizaki Rats.
    Life sciences, 2005, Apr-22, Volume: 76, Issue:23

    Topics: Administration, Oral; Animals; Carbonates; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diet; Disease Models, Animal; Enzyme Inhibitors; Female; Glucose; Glucose Tolerance Test; Glucosides; Hyperglycemia; Insulin Resistance; Male; Membrane Glycoproteins; Monosaccharide Transport Proteins; Rats; Rats, Inbred Strains; Rats, Wistar; Sodium; Sodium-Glucose Transporter 1; Time Factors

2005
Reduction of renal transport maximum for glucose by inhibition of NA(+)-glucose cotransporter suppresses blood glucose elevation in dogs.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:1

    Topics: Animals; Blood Glucose; Carbonates; Dogs; Dose-Response Relationship, Drug; Female; Glucose; Glucose Tolerance Test; Glucosides; Hyperglycemia; Kidney; Male; Postprandial Period; Sodium; Sodium-Glucose Transport Proteins

2006
Glucose toxicity is responsible for the development of impaired regulation of endogenous glucose production and hepatic glucokinase in Zucker diabetic fatty rats.
    Diabetes, 2006, Volume: 55, Issue:9

    Topics: Animals; Blood Glucose; Carbonates; Carrier Proteins; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Glucagon; Glucokinase; Glucose; Glucose-6-Phosphatase; Glucosides; Glycogen; Glycogen Synthase; Hyperglycemia; Insulin; Liver; Liver Glycogen; Male; Muscle, Skeletal; Phosphorylases; Rats; Rats, Zucker

2006
Desoxyrhaponticin (3,5-dihydroxy-4'-methoxystilbene 3-O-beta-D-glucoside) inhibits glucose uptake in the intestine and kidney: In vitro and in vivo studies.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:1

    Topics: Animals; Biological Transport; Diabetes Mellitus, Experimental; Glucose; Glucosides; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Intestinal Mucosa; Kidney; Microvilli; Rabbits; Rats; Rats, Wistar; Stilbenes

2007
Cyanidin 3-glucoside ameliorates hyperglycemia and insulin sensitivity due to downregulation of retinol binding protein 4 expression in diabetic mice.
    Biochemical pharmacology, 2007, Dec-03, Volume: 74, Issue:11

    Topics: Adipokines; Adiponectin; Adipose Tissue, White; Animals; Anthocyanins; Blood Glucose; Blotting, Western; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Down-Regulation; Glucose Tolerance Test; Glucose Transporter Type 4; Glucose-6-Phosphatase; Glucosides; Hyperglycemia; Inflammation Mediators; Insulin Resistance; Liver; Male; Mice; Mice, Inbred Strains; Molecular Structure; Receptors, Adiponectin; Retinol-Binding Proteins, Plasma; Reverse Transcriptase Polymerase Chain Reaction

2007
Increase of beta-endorphin secretion by syringin, an active principle of Eleutherococcus senticosus, to produce antihyperglycemic action in type 1-like diabetic rats.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2007, Volume: 39, Issue:12

    Topics: Adrenal Medulla; Adrenalectomy; Animals; beta-Endorphin; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Eleutherococcus; Glucosides; Hyperglycemia; Hypoglycemic Agents; Injections, Intravenous; Male; Mice; Mice, Knockout; Phenylpropionates; Phytotherapy; Rats; Rats, Wistar; Receptors, Opioid, mu; Streptozocin; Tissue Extracts

2007
Systemic absorption of insulin and glucagon applied topically to the eyes of rats and a diabetic dog.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1995,Fall, Volume: 11, Issue:3

    Topics: Absorption; Administration, Topical; Animals; Blood Glucose; Detergents; Diabetes Mellitus; Dogs; Drug Carriers; Eye; Gastrointestinal Agents; Glucagon; Glucosides; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Nasal Mucosa; Ophthalmic Solutions; Rats; Rats, Sprague-Dawley

1995
Hyperglycemia impairs the insulin signaling step between PI 3-kinase and Akt/PKB activations in ZDF rat liver.
    Biochemical and biophysical research communications, 1999, Dec-09, Volume: 266, Issue:1

    Topics: Animals; Blood Glucose; Body Weight; Carbonates; Dose-Response Relationship, Drug; Enzyme Activation; Glucosides; Hyperglycemia; Insulin; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Liver; Membrane Glycoproteins; Monosaccharide Transport Proteins; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Zucker; Receptor, Insulin; Signal Transduction; Sodium-Glucose Transporter 1; Time Factors

1999
Hyperglycemia contributes insulin resistance in hepatic and adipose tissue but not skeletal muscle of ZDF rats.
    American journal of physiology. Endocrinology and metabolism, 2000, Volume: 278, Issue:3

    Topics: Adipocytes; Adipose Tissue; Animals; Blood Glucose; Carbonates; Diabetes Mellitus; Glucokinase; Glucose Transporter Type 4; Glucose-6-Phosphatase; Glucosides; Hyperglycemia; Hyperinsulinism; Insulin Resistance; Liver; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Obesity; Rats; Rats, Zucker

2000
Oxidative stress as a mechanism of diabetes in diabetic BB prone rats: effect of secoisolariciresinol diglucoside (SDG).
    Molecular and cellular biochemistry, 2000, Volume: 209, Issue:1-2

    Topics: Animals; Butylene Glycols; Diabetes Mellitus, Type 1; Glucosides; Glycosuria; Humans; Hyperglycemia; Lipid Peroxidation; Malondialdehyde; Oxidative Stress; Pancreas; Rats; Rats, Inbred BB; Reactive Oxygen Species

2000
T-1095, a renal Na+-glucose transporter inhibitor, improves hyperglycemia in streptozotocin-induced diabetic rats.
    Metabolism: clinical and experimental, 2000, Volume: 49, Issue:8

    Topics: Albuminuria; Animals; Blood Glucose; Body Weight; Carbonates; Diabetes Mellitus, Experimental; Glucose Transporter Type 2; Glucosides; Glycated Hemoglobin; Glycosuria; Hyperglycemia; Hypoglycemic Agents; Jejunum; Kidney; Male; Monosaccharide Transport Proteins; Organ Size; Rats; Rats, Wistar; Sodium-Glucose Transporter 2; Urine

2000
Correction of hyperglycemia and insulin sensitivity by T-1095, an inhibitor of renal Na+-glucose cotransporters, in streptozotocin-induced diabetic rats.
    Japanese journal of pharmacology, 2000, Volume: 84, Issue:3

    Topics: Animals; Carbonates; Deoxyglucose; Diabetes Mellitus, Experimental; Glucosides; Hyperglycemia; Hypoglycemic Agents; In Vitro Techniques; Insulin Resistance; Lactic Acid; Male; Monosaccharide Transport Proteins; Muscle, Skeletal; Rats

2000
Antihyperglycemic effect of T-1095 via inhibition of renal Na+-glucose cotransporters in streptozotocin-induced diabetic rats.
    Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:12

    Topics: Animals; Blood Glucose; Carbonates; Diabetes Mellitus, Experimental; Glucosides; Glycosuria; Hyperglycemia; Hypoglycemic Agents; Kidney; Male; Microvilli; Monosaccharide Transport Proteins; Rats; Rats, Sprague-Dawley; Rats, Wistar

2000
Inhibition of alpha-glucosidase and amylase by luteolin, a flavonoid.
    Bioscience, biotechnology, and biochemistry, 2000, Volume: 64, Issue:11

    Topics: alpha-Glucosidases; Amylases; Biflavonoids; Enzyme Inhibitors; Flavonoids; Glucosides; Glycoside Hydrolase Inhibitors; Humans; Hyperglycemia; Isoflavones; Luteolin

2000
Stevioside induces antihyperglycaemic, insulinotropic and glucagonostatic effects in vivo: studies in the diabetic Goto-Kakizaki (GK) rats.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2002, Volume: 9, Issue:1

    Topics: Animals; Area Under Curve; Diabetes Mellitus, Type 2; Disease Models, Animal; Diterpenes; Diterpenes, Kaurane; Glucagon; Glucose; Glucose Tolerance Test; Glucosides; Hyperglycemia; Hypoglycemic Agents; Injections, Intravenous; Insulin; Male; Phytotherapy; Plant Extracts; Rats; Rats, Inbred Strains; Rats, Wistar; Terpenes

2002
Normalization of cytoplasmic calcium response in pancreatic beta-cells of spontaneously diabetic GK rat by the treatment with T-1095, a specific inhibitor of renal Na+-glucose co-transporters.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2002, Volume: 34, Issue:4

    Topics: Animals; Arginine; Blood Glucose; Calcium; Carbonates; Diabetes Mellitus, Type 2; Glucosides; Glycated Hemoglobin; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Male; Monosaccharide Transport Proteins; Rats; Rats, Wistar

2002
Sucrose malabsorption in man after ingestion of alpha-glucosidehydrolase inhibitor.
    Lancet (London, England), 1978, Jun-10, Volume: 1, Issue:8076

    Topics: Administration, Oral; Adult; Blood Glucose; Breath Tests; Deuterium; Enzyme Inhibitors; Female; Glucosidases; Glucosides; Glycoside Hydrolase Inhibitors; Humans; Hyperglycemia; Intestinal Absorption; Malabsorption Syndromes; Male; Middle Aged; Sucrose

1978