glucose, (beta-d)-isomer has been researched along with Disease Models, Animal in 937 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (1.71) | 18.7374 |
| 1990's | 64 (6.83) | 18.2507 |
| 2000's | 139 (14.83) | 29.6817 |
| 2010's | 475 (50.69) | 24.3611 |
| 2020's | 243 (25.93) | 2.80 |
| Authors | Studies |
|---|---|
| Canaud, B; Dézsi, L; Mészáros, T; Mollnes, TE; Moore, C; Pethő, Á; Piecha, D; Rosivall, L; Steppan, S; Szebeni, J; Szénási, G; Urbanics, R | 1 |
| Ansari, SA; Hasan, A; Jawed, A; Jilani, SNA; Khan, JA; Kiyani, A; Roome, T; Wahid, M | 1 |
| Arena, AC; de Matos Balsalobre, N; Dos Santos, E; Konkiewitz, EC; Leite Kassuya, CA; Mariano Dos Santos, S; Nazari Formagio, AS; Ziff, EB | 1 |
| Arena, AC; Bernal, LPT; Cardoso, CAL; Fraga, TL; Kassuya, CAL; Leitão, MM; Lencina, JDS; Radai, JAS; Silva-Filho, SE | 1 |
| Li, Y; Long, X; Luo, C; Tang, W; Xie, L; Zhang, Q | 1 |
| Chen, B; Chen, Z; Han, H; Huang, C; Lu, X; Ye, T; Zhao, H; Zheng, M; Zhu, T | 1 |
| Dimmito, MP; Dvorácskó, S; Minosi, P; Mollica, A; Pieretti, S; Stefanucci, A; Tömböly, C; Zengin, G | 1 |
| Kim, WJ; Lee, J; Yeo, J; Yoon, S | 1 |
| Chen, S; Dou, H; Fu, J; Hou, Y; Li, X; Liang, H; Zhu, H | 1 |
| Alexis, F; Almeida Pádua, T; Barbosa Corrêa, L; Cruz Rosas, E; de OliveiraHenriques, MD; Hussain Iram, S; Leal Portilho, F; Magalhaes Rebelo Alencar, L; Moia, VM; Ricci-Junior, E; Sampson, A; Santos-Oliveira, R; Savio Mendes Sinfronio, F | 1 |
| Artero, NA; Badaro-Garcia, S; Casagrande, R; de Freitas, A; Fattori, V; Ferraz, CR; Manchope, MF; Rasquel-Oliveira, FS; Saraiva-Santos, T; Staurengo-Ferrari, L; Verri, WA; Zaninelli, TH | 1 |
| Feng, Z; Guo, J; Jiang, HX; Liu, BL; Liu, WJ; Liu, YN; Wang, Y; Xia, CH; Zhang, W; Zhu, ZB | 1 |
| Carvalho, DCM; Cavalcante-Silva, LHA; Costa, PRR; Lima, ÉA; Netto, CD; Rodrigues-Mascarenhas, S | 1 |
| Jia, L; Li, J; Song, X; Zhang, J | 1 |
| Epstein, JA; Feldman, AM; Rosenthal, N | 1 |
| Cha, HS; Chung, TY; Han, J; Kim, J; Kim, YD; Lim, DH; Park, DY; Park, S; Woo, KI | 1 |
| Alencar, POC; Barbosa, ALDR; Barros, FCN; Bingana, RD; Chaves, LS; Damasceno, ROS; Freitas, ALP; Medeiros, JR; Morais, PAF; Oliveira, FFB; Oliveira, SRBD; Soares, PMG; Souza, MHLP | 1 |
| Bosso, MA; Ezeamuzie, CI; Phillips, OA | 1 |
| Bao, B; Gao, T; Lin, J; Wei, H; Zheng, X; Zhu, H | 1 |
| Aratani, Y; Endo, D; Sugimoto, Y | 1 |
| Carvalho, DCM; de Almeida Lima, É; de Almeida Vasconcellos, MLA; de França, JS; de Sales-Neto, JM; Lima-Junior, CG; Mendes, RKS; Olegário, TR; Rodrigues-Mascarenhas, S | 1 |
| Aguero Ito, CN; Arena, AC; Dos Santos, E; Leitão, MM; Leite Kassuya, CA; Nakamura Cuman, RK; Nazari Formagio, AS; Oliveira, RJ; Silva-Comar, FMS; Silva-Filho, SE | 1 |
| He, Y; Jiang, L; Li, Q; Long, H; Long, S; Xiao, Z; Yang, W; Zou, C | 1 |
| Brüne, B; Cohnen, J; Ebersberger, I; Ebersberger, S; Ferreirós, N; Kolbinger, A; Kornstädt, L; Pierre, S; Schäufele, TJ; Schmid, T; Scholich, K; Thomas, D; Weigert, A | 1 |
| Brod, S; D'Acquisto, F; Gittens, B; Gobbetti, T; Ono, M; Perretti, M | 1 |
| Choi, JJ; Chun, E; Do, SG; Jin, M; Kho, YT; Kim, SY; Kim, TW; Lee, TH; Oh, SH; Park, BK; Shin, E; Shin, Y | 1 |
| Ervolino, E; Issa, JPM; Lilge, L; Macedo, AP; Trawitzki, BF | 1 |
| Arai, S; Hiramoto, E; Ito, Y; Kitada, K; Maruyama, S; Matsuo, S; Miyazaki, T; Mizuno, M; Nakano, D; Nishiyama, A; Sakata, F; Suzuki, Y; Takei, Y; Tomita, T | 1 |
| Cavalcante, ALC; de Araújo, JCB; de Castro Brito, GA; Gondim, DV; Lisboa, MRP; Vale, ML | 1 |
| Akashi, K; Morinobu, A; Okano, T; Saegusa, J; Sendo, S; Takahashi, S | 1 |
| Benarafa, C; Burgener, SS; Candalh, C; Dahdah, A; Foretz, M; Launay, P; Lauret, E; Lucas, B; Martin, KR; Mouthon, L; Pacreau, E; Pederzoli-Ribeil, M; Thieblemont, N; Witko-Sarsat, V | 1 |
| Guden, DS; Kocak, Z; Kucukkavruk, SP; Malik, KU; Sahan-Firat, S; Sari, AN; Temiz-Resitoglu, M; Tunctan, B | 1 |
| Araujo, JMD; Camargo, EA; Felix, FB; Grespan, R; Silva, LAS; Souza, EV | 1 |
| Bae, EK; Cha, HS; Chung, TY; Jeon, CH; Jeong, H; Kim, H; Koh, EM; Lee, J; Lim, DH | 1 |
| Deng, Y; Huang, H; Li, S; Peng, L; Wang, B; Yang, R; Yuan, J; Zhang, H; Zhong, J | 1 |
| Achuthan, A; Christensen, AD; Cook, AD; Fleetwood, AJ; Förster, I; Hamilton, JA; Khiew, HW; Lacey, DC; Lee, MC; Saleh, R; Smith, JE | 1 |
| Akagi, M; Hashimoto, K; Ikeda, T; Nakagawa, K; Oda, Y; Ohtani, K | 1 |
| Alcaraz, MJ; Brines, R; Catalán, L; Ferrándiz, ML | 1 |
| Angioni, C; Geisslinger, G; Osthues, T; Pierre, SC; Scholich, K; Sisignano, M; Thomas, D; Toewe, A; Zimmer, B | 1 |
| Araújo-Júnior, JX; de Miranda, GEC; de Moura, AMA; Guedes, PMM; Jales, JT; Lucena, AMM; Nascimento, GJ; Santos, BVO; Scortecci, KC; Souto, JT; Souza, CRM | 1 |
| Kokkotou, E; Korniotis, S; Koulmanda, M; Kyriazis, P; Li, LS; Ma, L; Strom, TB; Theodorou, E; Thornley, TB | 1 |
| Iguchi, D; Ito, Y; Maruyama, S; Mizuno, M; Okada, A; Okada, H; Sakata, F; Suzuki, Y | 1 |
| Chun, E; Jin, M; Parveen, A; Yoon, S | 1 |
| Buharalioglu, CK; Cil, M; Guden, DS; Korkmaz, B; Malik, KU; Sahan-Firat, S; Sari, AN; Senol, SP; Temiz-Resitoglu, M; Tunctan, B; Unsal, D | 1 |
| Carreras, E; Català, C; Lozano, F; Orta-Mascaró, M; Simões, IT; Velasco de Andrés, M; Zaragoza, O | 1 |
| Borghi, SM; Bussmann, AJC; Camilios-Neto, D; Casagrande, R; Casella, AMB; Domiciano, TP; Dos Santos, TS; Fattori, V; Guazelli, CFS; Pinho-Ribeiro, FA; Ruiz-Miyazawa, KW; Verri, WA; Vignoli, JA; Zaninelli, TH | 1 |
| Hu, LN; Liu, SB; Lu, L; Tian, Z; Wang, XS; Yang, LK; Yue, J; Zhao, MG | 1 |
| Azcutia, V; Denning, TL; Flemming, S; Hilgarth, RS; Kim, W; Leary, MNO; Luissint, AC; Nusrat, A; Parkos, CA; Williams, HC | 1 |
| Ahuja, S; Akhtar, A; Sah, SP; Uniyal, A | 1 |
| Alexis, A; Carrer, DP; Giamarellos-Bourboulis, EJ; Kotsaki, A; Louis, K; Mylona, V; Netea, MG; Pistiki, A; Roditis, K; Savva, A; Van der Meer, JW | 1 |
| Ackland, GL; Gourine, AV; Kazymov, V; Marina, N; Singer, M | 1 |
| Beckerman, SR; Lemmon, VP; Luo, X; Park, KK; Salgueiro, Y; Tsoulfas, P | 1 |
| Brown, GD; Engstad, R; Hoving, JC; Marakalala, MJ; Netea, MG; Williams, DL | 1 |
| Cao, L; Dong, H; Hou, L; Jia, W; Jing, W; Wang, C; Wei, H; Yang, S; Zhang, Y | 1 |
| Chen, SH; Cheng, JT; Chung, HH; Ku, PM; Wang, LY; Yu, YM | 1 |
| Karmarkar, D; Rock, KL | 1 |
| Furuhashi, K; Ito, Y; Katsuno, T; Kim, H; Maruyama, S; Matsuo, S; Mizuno, M; Ozaki, T; Sato, W; Suzuki, Y; Tsuboi, N; Yasuda, K | 1 |
| Banoglu, E; Barz, D; Çalışkan, B; Gerstmeier, J; Luderer, S; Maczewsky, J; Mönch, B; Pace, S; Pergola, C; Rossi, A; Sautebin, L; Weinigel, C; Werz, O | 1 |
| Arriaga, AM; Arriaga, NC; Benevides, NM; Bezerra, MM; Brito, GA; Chaves, HV; Cristino-Filho, G; do Val, DR; Lemos, JC; Pereira, KM; Pinto, VP; Rios, LC; Santiago, GM; Silva, AA; Silva, FR; Vasconcelos, JN | 1 |
| Goss, KL; Hilkin, BM; Hook, JS; Moreland, JG; Newell, EA; Whitmore, LC | 1 |
| Chang, DJ; Kim, WJ | 1 |
| Ishikawa, Y; Mimori, T; Murakami, K; Shimizu, M; Shiomi, A; Usui, T | 1 |
| Han, SB; Hong, JT; Jung, JK; Kang, JS; Kim, HS; Kim, JS; Kim, Y; Kim, YG; Kwak, YS; Lee, HK; Lee, K; Ryu, HS; Seo, SY; Yun, J | 1 |
| Jeong, YC; Kwon, YB; Pyun, K | 1 |
| Berg, BM; Bruckert, M; Chichlowski, M; Kannampalli, P; Miranda, A; Pochiraju, S; Rudolph, C; Sengupta, JN | 1 |
| Huang, Z; Liu, C; Liu, S; Liu, Y; Pang, Q; Song, S; Wu, Q; Zhang, J; Zhang, R | 1 |
| Machado, PR; Martinez, CA; Nonose, N; Pereira, JA; Rodrigues, MR; Sato, DT | 1 |
| Chen, Q; Guo, F; Han, J; He, H; Hu, S; Huang, Y; Liu, A; Liu, L; Qiu, H; Xu, J; Xu, X; Yang, Y | 1 |
| Ji, G; Li, Z; Neugebauer, V | 1 |
| Cha, YN; Chung, HT; Jang, J; Jin, HO; Joe, Y; Kim, C; Kim, HU; Kim, K; Kim, SH; Kim, W; Lee, HN; Lee, JK; Suh, YG; Surh, YJ | 1 |
| Figueiredo, MJ; Kanashiro, A; Malvar, Ddo C; Souza, GE | 1 |
| Gebhart, GF; La, JH; Schwartz, ES; Xie, A | 1 |
| Bassi, GS; Brognara, F; Castania, JA; Cunha, FQ; Cunha, TM; Dias, DP; Kanashiro, A; Salgado, HC; Talbot, J; Ulloa, L | 1 |
| Byun, JK; Cho, ML; Jeong, JH; Jhun, J; Jung, YO; Kim, EK; Lee, J; Lee, SH; Park, SH; Shin, D | 1 |
| Beck, KF; Boosen, M; Geisslinger, G; Hohmann, SW; Kallenborn-Gerhardt, W; Köhler, Y; Longen, S; Pfeilschifter, J; Schmidtko, A; Syhr, KMJ | 1 |
| Brown, BR; Clowers, JS; Lee, EJ; Rosenzweig, HL; Sakaguchi, S; Snow, PS; Vance, EE | 1 |
| Ben-Hur, T; Einstein, O; Fainstein, N; Luz, A | 1 |
| Jeong, YC; Kwon, YB; Son, JS | 1 |
| Cheng, LF; Liu, SB; Lu, JS; Shi, J; Zhang, MM; Zhuo, M | 1 |
| Boyken, J; Dahllöf, H; Laux-Biehlmann, A; Nagel, J; Schmidt, N; Zollner, TM | 1 |
| Choi, JW; Jeon, SJ; Lee, Y; Ryu, JH | 1 |
| Cho, NJ; Fülöp, T; Jackman, JA; Mészáros, T; Szebeni, J; Urbanics, R | 1 |
| Goshima, Y; Kitamura, Y; Nagai, J; Ohshima, T; Owada, K | 1 |
| Gao, CF; Jia, LT; Li, JT; Liu, NN; Liu, QQ; Wang, L; Wang, WQ; Yang, AG; Zhao, YL; Zhu, XS | 1 |
| Adage, T; Gerlza, T; Gschwandtner, M; Kungl, AJ; Piccinini, AM | 1 |
| Armstrong, MG; Hall, JV; Hoover, DB; Li, C; Monroe, LL; Ozment, TR; Williams, DL; Zhang, X | 1 |
| Bressan, E; Cury, Y; Fischer, MJM; Kichko, TI; Kistner, K; Lewis, RJ; Picolo, G; Reeh, PW; Teixeira, NB; Touska, F; Vetter, I; Zimmermann, K | 1 |
| Bitencourt, MAO; da Silva Siqueira, EM; Estrela, AB; Fernandes-Pedrosa, MF; Furtado, AA; Lima, MCJS; Lopes, NP; Silva-Júnior, AA; Souza da Silva, N; Tomaz, JC; Torres-Rêgo, M; Zucolotto, SM | 1 |
| Breyer, RM; Ji, Y; Kong, D; Lazarus, M; Liu, G; Lu, A; Nakamura, M; Shen, Y; Stratakis, CA; Yu, Y; Zuo, S | 1 |
| Cooper, D; Flak, MB; Norling, LV; Souza, PR; Thedchanamoorthy, P; Wright, RD | 1 |
| Adams, BS; Almburg, SJ; Amin, MA; Angevine, K; Carmona-Rivera, C; Engelke, DR; Fox, DA; Gonzales-Hernandez, MJ; Jorns, J; Kaplan, MJ; Knight, JS; Koch, AE; Legendre, M; Markovitz, DM; Mohan, S; Mor-Vaknin, N; Pai, DA; Rabquer, BJ; Saha, A; Yalavarthi, S | 1 |
| Cardoso, VN; Diniz, SO; Ferreira, RL; Martin-Comin, J; Rezende, CM; Ribeiro, TG; Serakides, R | 1 |
| Fei, J; Fei, Z; Li, L; Liu, Z; Ren, J; Sheng, Z; Sun, R; Sun, X; Wang, L; Wang, Z; Yu, J | 1 |
| Han, HJ; Jeon, MJ; Kang, SY; Kim, HW; Kwon, YB; Lee, HJ; Lee, JH; Roh, DH; Seo, HS; Uh, DK; Yoon, SY | 1 |
| Herschman, HR; Ishikawa, TO; Jain, NK; Spigelman, I | 1 |
| Huang, YL; Kou, JP; Ma, L; Song, JX; Yu, BY | 1 |
| Hou, L; Ji, G; Li, N; Lu, Y; Ma, S; Qin, M; Xie, K; Xiong, L | 1 |
| Garssen, J; Hartog, A; Hoijer, MA; Smit, HF; van der Kraan, PM | 1 |
| Cho, ML; Ju, JH; Jung, YO; Kim, HY; Kim, SI; Lee, SY; Min, JK; Oh, HJ; Park, JS; Park, MJ; Park, MK; Park, SH | 1 |
| Cash, JL; Greaves, DR; White, GE | 1 |
| Feng, B; Gebhart, GF; Shinoda, M | 1 |
| Harris, CL; Hepburn, N; Ito, Y; Matsuo, S; Mizuno, M; Mizuno, T; Morgan, BP; Noda, Y; Yuzawa, Y | 1 |
| Avsar, FM; Berkem, H; Guc, MO; Guler, G; Hengirmen, S; Iskit, AB; Ozel, H; Yuksel, BC | 1 |
| Arai, H; Arita, M; Inoue, M; Ogawa, S; Urabe, D; Yokokura, Y | 1 |
| Galligan, C; Takahashi, M; Tessarollo, L; Yoshimura, T | 1 |
| Arruda, JM; Baccei, C; Bain, G; Broadhead, AR; Chapman, C; Correa, LD; Darlington, JV; Evans, JF; Hutchinson, JH; King, C; Lee, C; Li, Y; Lorrain, DS; Prodanovich, P; Santini, AM | 1 |
| Ahmed, Z; Aslam, M; Berry, M; Logan, A; Lorber, B; Suggate, EL | 1 |
| DeBerry, J; Ness, TJ; Randich, A; Robbins, MT; Shaffer, AD | 1 |
| Cunha, FQ; Cunha, TM; Ferreira, SH; Lemos, HP; Pinto, LG; Verri, WA; Vieira, SM | 1 |
| Bian, Z; Chen, X; Chen, YY; Guo, YL; Liu, DQ; Liu, Y; Zen, K; Zhang, CY | 1 |
| Adams, M; Baillie, GS; Bartlett, JB; Capone, L; Cheung, YF; Gandhi, AK; Gilhar, A; Houslay, MD; Loveland, MA; Man, HW; Muller, GW; Parton, A; Schafer, PH; Stirling, DI; Wu, L | 1 |
| Matsushima, H; Miyazaki, T; Nishibu, A; Ogawa, Y; Takashima, A; Tanaka, H | 1 |
| Berg, JT | 1 |
| Baccei, CS; Bain, G; Broadhead, AR; Chapman, C; Correa, LD; Darlington, JV; Evans, JF; Hutchinson, JH; King, CD; Lee, C; Lorrain, DS; Prasit, P; Prodanovich, PP; Roppe, J; Santini, AM; Stearns, B; Stock, NS; Zunic, J | 1 |
| Kornerup, KN; Liu, WL; Page, CP; Pitchford, SC; Salmon, GP | 1 |
| Amin, MA; Koch, AE; Lesch, C; Marotte, H; Park, CC; Ruth, JH; Shahrara, S | 1 |
| Jia, Y; Li, XH; Liu, Y; Zhang, HG | 1 |
| Andrieu, V; Beaumont, C; Bennada, S; Charrier, JL; Hurtado-Nedelec, M; Karim, Z; Lasocki, S; Letteron, P; Lyoumi, S; Millot, S; Thibaudeau, O | 1 |
| Bramanti, P; Cuzzocrea, S; Dehm, F; Hoffmann, M; Koeberle, A; Pergola, C; Rossi, A; Sautebin, L; Werz, O | 1 |
| Bartnik, E; Caglič, D; Globisch, A; Jeske, V; Juretschke, HP; Kindermann, M; Lim, NH; Nagase, H; Turk, B; Weithmann, KU; Wendt, KU | 1 |
| Bezerra, MM; Brito, GA; Chaves, HV; de Souza, AM; Gomes, AS; Ribeiro, Rde A; Rodrigues e Silva, AA; Vale, ML | 1 |
| Ashton, SH; Borg, KT; Cook, JA; Fan, H; Halushka, PV; Wong, D | 1 |
| Clowers, JS; Davey, MP; Nunez, G; Rosenbaum, JT; Rosenzweig, HL | 1 |
| Barres, BA; Mandemakers, WJ; Phillips, CT; Stafford, M; Sun, MZ; Winzeler, AM | 1 |
| Ha, N; Hwang, IC; Kim, DH; Kim, JM; Lee, S; Lee, SS; Lim, IT; Park, JH; You, JA; Yu, H | 1 |
| Capuano, A; Cuzzocrea, S; Di Palma, D; Di Paola, R; Donniacuo, M; Imperatore, F; Mazzon, E; Rinaldi, B; Rossi, F; Sodano, L | 1 |
| Chaikof, EL; Dougherty, A; Haller, CA; Krishnamurthy, VR | 1 |
| Deng, W; Jia, Y; Li, H; Li, X; Liao, Y; Liu, K; Tan, Z; Tian, G; Yuan, Z; Zhang, H; Zhang, Y | 1 |
| Bailey, AL; Bennett, GJ; Binik, YM; Crissman, HP; Farmer, MA; MacIntyre, LC; Milagrosa, ZE; Mogil, JS; Ribeiro-da-Silva, A; Taylor, AM; Tuttle, AH | 1 |
| Austin, JS; Beggs, S; Chanda, ML; Graham, AC; LaCroix-Fralish, ML; Mogil, JS; Ritchie, J; Salter, MW; Sorge, RE; Sotocinal, SG; Topham, L; Tuttle, AH | 1 |
| Bian, Z; Guo, Y; Ha, B; Liu, Y; Zen, K | 1 |
| Lu, QY; Meng, L; Quan, S; Wang, JB; Wang, L; Weng, JK; Yu, B; Zhou, YY | 1 |
| Bao, YX; Fan, X; Gu, Y; Liang, HP; Yang, X; Zhang, C | 1 |
| Harris, CL; Ito, Y; Matsuo, S; Mizuno, M; Mizuno, T; Morgan, BP; Okada, N; Suzuki, Y | 1 |
| Beaumont, C; Denamur, E; Driss, F; El Benna, J; Heming, N; Lasocki, S; Lettéron, P; Millot, S; Montravers, P; Tourret, J | 1 |
| Chen, GJ; Chen, W; Du, J; Huang, YG; Luo, AL; Wang, JJ | 1 |
| Chen, Y; Gao, Q; Gao, Y; Jiang, R; Liu, W; Qie, J; Xu, D | 1 |
| Kerr, BJ; Kulkarni, A; Tenorio, G | 1 |
| Kolaczkowska, E; Mazur-Bialy, AI; Plytycz, B | 1 |
| Cunha, FQ; Cunha, TM; Ferreira, SH; Guerrero, AT; Pinto, LG; Verri, WA; Vieira, SM; Zaperlon, AC; Zarpelon, AC | 1 |
| Gao, L; Guo, NN; Kang, JR; Li, F; Lu, JY; Sun, JZ; Wang, HW; Yang, W; Zhang, W | 1 |
| Addya, S; Banerjee, B; Bruckert, M; Kannampalli, P; Miranda, A; Pochiraju, S; Sengupta, JN; Shaker, R; Yadav, P | 1 |
| Antonini, JM; Kashon, ML; Roberts, JR; Wolfarth, MG; Young, SH | 1 |
| Guo, H; Li, F; Liu, Q; Lu, JY; Wang, HW | 1 |
| Basso, DM; Fisher, L; Guan, Z; Hickey, WF; McGaughy, V; Popovich, PG | 1 |
| Beitz, AJ; Ham, TW; Han, HJ; Kim, HW; Kwon, YB; Lee, JH; Roh, DH; Yang, IS; Yoon, SY | 1 |
| Geisslinger, G; Grösch, S; Niederberger, E; Schäfer, C; Seegel, M; Tegeder, I | 1 |
| Alcaraz, MJ; Guillín, MI; Vicente, AM | 1 |
| McLachlan, SM; Nagayama, Y; Niwa, M; Rapoport, B | 1 |
| Alves, M; del Olmo, E; Lucas, R; Payá, M; San Feliciano, A | 1 |
| Gábor, M | 1 |
| Seed, MP | 1 |
| Hu, S; Jiang, XG; Jin, H; Li, JY; Lu, JY; Lü, Y; Sheng, ZY; Zhang, R | 1 |
| Hu, S; Lu, JY; Sun, Y; Tong, X; Wang, XH; Yang, Y | 1 |
| Caputi, AP; Chatterjee, PK; Cuzzocrea, E; Cuzzocrea, S; Di Paola, R; Fulia, F; Genovese, T; Ianaro, A; Patel, NS; Pisano, B; Rossi, A; Sautebin, L; Thiemermann, C | 1 |
| Senftleben, U | 1 |
| Blask, D; Dauchy, R; Dietz, PA; Lynch, D; Reynolds, FD; Zuckerman, R | 1 |
| Alcaraz, MJ; Charris, J; De León, EJ; Dominguez, JN; Terencio, MC | 1 |
| Bezerra, MM; Brain, SD; da Rocha, FA; de Melo, LB; Greenacre, S; Jerônimo, SM; Keeble, J | 1 |
| Caputi, AP; Cuzzocrea, E; Cuzzocrea, S; Di Paola, R; Dugo, L; Fulia, F; Genovese, T; Mazzon, E; Salvemini, D; Serraino, I | 1 |
| Geisslinger, G; Gühring, H; Kunz, S; Michaelis, M; Niederberger, E; Ritzeler, O; Schmidt, R; Tegeder, I | 1 |
| Cooper, D; Hall, JC; McCauley, R; Platell, C; Yao, V | 1 |
| Han, JS; Neugebauer, V | 1 |
| Tokita, K; Yamamoto, T | 1 |
| Autore, G; Britti, D; Cuzzocrea, S; Di Paola, R; Genovese, T; Marzocco, S; Pinto, A; Scollo, G; Sorrentino, R | 1 |
| Chacur, M; Maier, SF; Marsh, H; Martin, D; Milligan, ED; Poole, S; Sloane, EM; Twining, CM; Watkins, LR | 1 |
| Lan, C; Liu, R; Tang, CW | 1 |
| Marshall, JC | 1 |
| Phelps, DS; Thomas, NJ; Umstead, TM | 1 |
| Goris, RJ; Hendriks, T; Volman, TJ | 1 |
| Bulger, EM; Jelacic, S; Maier, RV; Staudenmayer, KL | 1 |
| Corvey, C; Coste, O; Geisslinger, G; Karas, M; Kunz, S; Marian, C; Niederberger, E; Pfenninger, A; Tegeder, I | 1 |
| Chatterjee, BE; Flower, RJ; Nourshargh, S; Perretti, M; Rosignoli, G; Yona, S; Young, RE | 1 |
| D'Amico, M; Di Filippo, C; Getting, SJ; Perretti, M | 1 |
| Brune, K; Budinsky, L; Hess, A; Sergejeva, M; Zeilhofer, HU | 1 |
| Arnold, B; Chadzinska, M; Kolaczkowska, E; Opdenakker, G; Plytycz, B; Scislowska-Czarnecka, A | 1 |
| Bradbury, EJ; Clark, AK; Gentry, C; Malcangio, M; McMahon, SB | 1 |
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| Cai, EB; Han, M; Li, G; Wang, SQ; Yang, LM; Yang, X; Zhang, YG; Zhao, Y; Zheng, XM | 1 |
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| Chen, N; Chu, X; Deng, X; Guan, S; Huo, M; Lu, J; Song, B; Song, Y; Wang, D; Xiong, Y | 1 |
| Qiao, M; Sun, S; Zhang, H | 1 |
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| Chen, TY; Cooper, B; Ferruzzi, MG; Gong, B; Ho, L; Janle, EM; Lobo, J; Pasinetti, GM; Percival, SS; Simon, JE; Talcott, ST; Wang, J; Wu, QL | 1 |
| Hara, H; Matsuda, H; Nakamura, S; Nakanishi, T; Shimazawa, M; Shimoda, H; Tanaka, J; Tsuruma, K; Yoshikawa, M | 1 |
| Chai, X; Kong, W; Liu, P; Shao, T; Song, L; Wen, X; Zhang, J | 1 |
| Chen, L; Deng, X; He, Y; Lan, Z; Lin, Q; Lin, Y; Mi, X; Wei, L; Zhang, Y | 1 |
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| Chen, X; Liu, C; Lu, L; Lu, Y; Lv, Z; Pan, Q; Xu, Q; Yang, Z | 1 |
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| Saito, A; Seiyaku, T; Tsujihara, K | 1 |
| Chen, J; Tan, KP; Thompson, LU; Ward, WE | 1 |
| Ijiri, Y; Oda, E; Sano, T; Shiramasa, H; Yamamoto, J; Yamashita, T | 1 |
| An, LJ; Bao, YM; Duan, YL; Li, DQ; Liu, CP; Liu, Y | 1 |
| Choi, EY; Choi, SC; Chung, HT; Jun, CD; Kim, KS; Kim, S; Kim, SW; Kim, TH; Kim, YS; Kimm, KC; Lee, HJ; Lee, MH; Oh, BS; Oh, HC; Oh, HM; Oh, JM; Pae, HO; Park, DS; Seo, GS; Woo, WH | 1 |
| Arakawa, K; Fujita, T; Ishihara, T; Matsumoto, Y; Nawano, M; Oku, A; Saito, A; Ueta, K | 1 |
| Gao, H; Zhou, YW | 1 |
| Ji, XQ; Jiang, CL; Liu, DZ; Xie, KQ; Ye, Y; Zhu, XZ | 1 |
| Liu, J; Luo, XT; Wang, YZ; Xiao, L; Ye, Y; Zhu, XZ | 1 |
| Das, A; Das, S; Mandal, S; Saha, P | 1 |
| Ahn, K; Joung, H; Kim, DY; Kim, JH; Kwon, OK; Lee, HK; Lee, J; Lee, MY; Lee, S; Oh, SR; Park, BY | 1 |
| Jin, DZ; Liu, J; Xiao, L; Zhu, XZ | 1 |
| Gao, Y; Guo, P; Li, YF; Liang, QD; Ma, BP; Ma, ZC; Tan, HL; Tan, W; Wang, SQ; Zhou, Z | 1 |
| Cheng, Y; Guo, S; Ouyang, S; Sun, L; Xu, J; Zhang, HT; Zhang, Y | 1 |
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19 review(s) available for glucose, (beta-d)-isomer and Disease Models, Animal
| Article | Year |
|---|---|
Advances of the experimental models of idiopathic membranous nephropathy (Review).
Topics: Animals; Complement Membrane Attack Complex; Disease Models, Animal; Glomerulonephritis, Membranous; Humans; Kidney; Kidney Glomerulus; Models, Theoretical; Podocytes; Receptors, Phospholipase A2; Renal Insufficiency, Chronic; Thrombospondins; Zymosan | 2020 |
Models of acute inflammation in the ear.
Topics: Alkynes; Animals; Anthralin; Arachidonic Acid; Cantharidin; Capsaicin; Carrageenan; Croton Oil; Dermatitis; Disease Models, Animal; Diterpenes; Edema; Foot; Inflammation; Irritants; Male; Mice; Models, Animal; Mustard Plant; Otitis Externa; Plant Extracts; Plant Oils; Rats; Reproducibility of Results; Terpenes; Tetradecanoylphorbol Acetate; Zymosan | 2003 |
The assessment of inflammation, cartilage matrix, and bone loss in experimental monoarticular arthritis of the rat.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Biomarkers; Bone Resorption; Cartilage, Articular; Cattle; Disease Models, Animal; Extracellular Matrix; Glycosaminoglycans; Immunosuppressive Agents; Inflammation; Male; Methylation; Models, Animal; Mycobacterium tuberculosis; Patella; Proteoglycans; Rats; Rats, Inbred Lew; Rats, Wistar; Rheumatic Diseases; Serum Albumin, Bovine; Species Specificity; Zymosan | 2003 |
NF-kappaB in critical diseases: a bad guy?
Topics: Animals; Antioxidants; Critical Illness; Disease Models, Animal; Gene Expression Regulation; Homeostasis; Humans; Inflammation; Mice; Multiple Organ Failure; NF-kappa B; Oxidation-Reduction; Proline; Signal Transduction; Thiocarbamates; Time Factors; Transcription Factors; Zymosan | 2003 |
Zymosan-induced generalized inflammation: experimental studies into mechanisms leading to multiple organ dysfunction syndrome.
Topics: Animals; Complement System Proteins; Cytokines; Disease Models, Animal; Humans; Inflammation; Mice; Models, Biological; Multiple Organ Failure; Oxidants; Rats; Time Factors; Zymosan | 2005 |
[Analysis of chemical mediators involved in acute inflammatory reaction with the rat pleurisy model].
Topics: Animals; Arachidonic Acid; Capillary Permeability; Carrageenan; Cell Movement; Chemokines; Complement System Proteins; Disease Models, Animal; Eicosanoids; Histamine; Inflammation; Kallikrein-Kinin System; Male; Neutrophils; Platelet Activating Factor; Pleurisy; Rats; Zymosan | 1997 |
Topics: Adult; Alcohol Drinking; Ammonia; Animals; Anti-Inflammatory Agents; Area Under Curve; B-Lymphocytes; Black or African American; Bleaching Agents; Body Mass Index; Brugada Syndrome; Carbon; China; Climate Models; Codon, Nonsense; Cohort Studies; Colitis; Colon; COVID-19; Cytokines; Dental Enamel; Dextran Sulfate; Disease Models, Animal; Disease Outbreaks; Dogs; Electrocardiography; Escherichia coli; Esophageal Neoplasms; Female; Follow-Up Studies; Forests; Georgia; Glucosides; Healthy Volunteers; Heart Ventricles; Hesperidin; HIV Infections; Humans; Humidity; Hydrogen Peroxide; Incidence; Influenza, Human; Longitudinal Studies; Magnetic Resonance Imaging, Cine; Male; Melanocortins; Mice; Mice, Inbred C57BL; Microscopy, Electron, Scanning; Middle Aged; Muscular Dystrophy, Duchenne; Naphthol AS D Esterase; Naphthols; Neoplasms; Nitrates; Nitrites; Nitrous Oxide; Obesity; Pandemics; Patient Outcome Assessment; Patient Satisfaction; Plants; Prednisolone; Prednisone; Pregnenediones; Proportional Hazards Models; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Rats; Receptor, Melanocortin, Type 1; Retrospective Studies; Risk Factors; SARS-CoV-2; Seasons; Soil; Stroke Volume; T-Lymphocytes; Telemedicine; Temperature; Tetralogy of Fallot; Tooth Bleaching; Tooth Bleaching Agents; Trees; Urea; White People | 2021 |
Efficacy of paeoniflorin on models of depression: A systematic review and meta-analysis of rodent studies.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Glucosides; Mice; Monoterpenes; Paeonia; Rats | 2022 |
Anti-Cancer Properties of
Topics: Animals; Antineoplastic Agents, Phytogenic; Clinical Studies as Topic; Disease Models, Animal; Diterpenes, Kaurane; Drug Evaluation, Preclinical; Glucosides; Humans; Inhibitory Concentration 50; Metabolic Networks and Pathways; Molecular Structure; Stevia; Structure-Activity Relationship; Sweetening Agents | 2022 |
Phytochemical and pharmacological properties of asperuloside, a systematic review.
Topics: Animals; Cyclopentane Monoterpenes; Disease Models, Animal; Glucosides; Humans; Phytochemicals; Pyrans | 2020 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; Delivery, Obstetric; Denitrification; Dental Caries; Denture, Complete; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dielectric Spectroscopy; Diet, High-Fat; Dietary Fiber; Disease Models, Animal; Disease Progression; DNA; DNA Copy Number Variations; DNA, Mitochondrial; Dog Diseases; Dogs; Dopaminergic Neurons; Double-Blind Method; Down-Regulation; Doxorubicin; Drug Carriers; Drug Design; Drug Interactions; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Dry Powder Inhalers; Dust; E2F1 Transcription Factor; Ecosystem; Education, Nursing; Education, Nursing, Baccalaureate; Electric Impedance; Electricity; Electrocardiography; Electrochemical Techniques; Electrochemistry; Electrodes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endothelial Cells; Environmental Monitoring; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Estrogen Receptor Modulators; Europe; Evoked Potentials, Auditory, Brain Stem; Exosomes; Feasibility Studies; Female; Ferricyanides; Ferrocyanides; Fibrinogen; Finite Element Analysis; Fistula; Fluorescent Dyes; Fluorides, Topical; Fluorodeoxyglucose F18; Fluticasone; Follow-Up Studies; Food Contamination; Food Microbiology; Foods, Specialized; Forensic Medicine; Frail Elderly; France; Free Radicals; Fresh Water; Fungi; Fungicides, Industrial; Galactosamine; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Hemorrhage; Glioblastoma; Glioma; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Glutamine; Glycolysis; Gold; GPI-Linked Proteins; Gram-Negative Bacteria; Gram-Positive Bacteria; Graphite; Haplotypes; HCT116 Cells; Healthy Volunteers; Hearing Loss; Heart Failure; Hedgehog Proteins; HEK293 Cells; HeLa Cells; Hemodynamics; Hemorrhage; Hepatocytes; Hippo Signaling Pathway; Histone Deacetylases; Homeostasis; Hospital Mortality; Hospitalization; Humans; Hydantoins; Hydrazines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hydroxylamines; Hypoglycemic Agents; Immunity, Innate; Immunoglobulin G; Immunohistochemistry; Immunologic Factors; Immunomodulation; Immunophenotyping; Immunotherapy; Incidence; Indazoles; Indonesia; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery; Inflammation; Injections, Intramuscular; Insecticides; Insulin-Like Growth Factor I; Insurance, Health; Intention to Treat Analysis; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Intrauterine Devices; Intrauterine Devices, Copper; Iron; Ischemia; Jordan; Keratinocytes; Kidney; Kidney Diseases; Kir5.1 Channel; Klebsiella Infections; Klebsiella pneumoniae; Lab-On-A-Chip Devices; Laparoscopy; Lasers; Lasers, Semiconductor; Lenalidomide; Leptin; Lethal Dose 50; Levonorgestrel; Limit of Detection; Lipid Metabolism; Lipid Metabolism Disorders; Lipogenesis; Lipopolysaccharides; Liquid Biopsy; Liver; Liver Abscess, Pyogenic; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Longevity; Lung Neoplasms; Luteolin; Lymph Nodes; Lymphocyte Activation; Macaca fascicularis; Macrophages; Mad2 Proteins; Magnetic Resonance Imaging; Male; Mammary Glands, Human; Manganese; Manganese Compounds; MAP Kinase Signaling System; Materials Testing; Maternal Health Services; MCF-7 Cells; Medicaid; Medicine, Chinese Traditional; Melanoma; Membrane Proteins; Mental Health; Mercury; Metal Nanoparticles; Metals, Heavy; Metformin; Methionine Adenosyltransferase; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Nude; Microalgae; Microbial Sensitivity Tests; Microglia; MicroRNAs; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mitochondria; Mitochondrial Proteins; Mitral Valve; Mitral Valve Insufficiency; Models, Anatomic; Molecular Structure; Molybdenum; Monocarboxylic Acid Transporters; Moths; MPTP Poisoning; Multigene Family; Multiparametric Magnetic Resonance Imaging; Multiple Myeloma; Muscle, Skeletal; Mutagens; Mutation; Myeloid Cells; Nanocomposites; Nanofibers; Nanomedicine; Nanoparticles; Nanowires; Neoadjuvant Therapy; Neomycin; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Neostriatum; Neovascularization, Pathologic; Netherlands; Neuromuscular Agents; Neurons; NF-E2-Related Factor 2; NF-kappa B; Nickel; Nitrogen Oxides; Non-alcoholic Fatty Liver Disease; Nucleosides; Nucleotidyltransferases; Nutritional Status; Obesity, Morbid; Ofloxacin; Oils, Volatile; Oligopeptides; Oncogene Protein v-akt; Optical Imaging; Organic Cation Transport Proteins; Organophosphonates; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteoblasts; Osteogenesis; Oxidation-Reduction; Oxidative Stress; Oxides; Oxygen Isotopes; Pancreas; Pancreaticoduodenectomy; Pandemics; Particle Size; Particulate Matter; Patient Acceptance of Health Care; Patient Compliance; PC-3 Cells; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Peroxides; Peru; Pest Control, Biological; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phylogeny; Pilot Projects; Piperidines; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Platelet Function Tests; Pneumonia, Viral; Podocytes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Terephthalates; Polymers; Polymorphism, Single Nucleotide; Porosity; Portugal; Positron-Emission Tomography; Postoperative Complications; Postural Balance; Potassium Channels, Inwardly Rectifying; Povidone; Powders; Precancerous Conditions; Precision Medicine; Predictive Value of Tests; Pregnancy; Prenatal Care; Prognosis; Promoter Regions, Genetic; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Proteasome Inhibitors; Protective Agents; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Psychiatric Nursing; PTEN Phosphohydrolase; Pulmonary Embolism; Pyrimethamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Recombinational DNA Repair; Recovery of Function; Regional Blood Flow; Renal Dialysis; Renin; Renin-Angiotensin System; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Distress Syndrome; Retrospective Studies; Rhodamines; Risk Assessment; Risk Factors; RNA, Long Noncoding; RNA, Messenger; Running; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Salmeterol Xinafoate; Sarcoma; Seasons; Shoulder Injuries; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Sirtuins; Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses | 2021 |
TaleNeprilysin and Neprilysin inhibition in chronic kidney disease.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzhydryl Compounds; Biphenyl Compounds; Cardiovascular Diseases; Chronic Disease; Disease Models, Animal; Disease Progression; Drug Combinations; Glucosides; Heart Failure; Humans; Mice; Natriuretic Peptides; Neprilysin; Renal Insufficiency, Chronic; Renin-Angiotensin System; Sodium-Glucose Transporter 2 Inhibitors; Valsartan | 2021 |
Potential protective properties of flax lignan secoisolariciresinol diglucoside.
Topics: Animals; Antioxidants; Butylene Glycols; Chemoprevention; Disease Models, Animal; Flax; Glucosides; Humans; Lignans; Phytochemicals; Plant Extracts | 2015 |
Prevention and treatment of atherosclerosis with flaxseed-derived compound secoisolariciresinol diglucoside.
Topics: Animals; Butylene Glycols; Coronary Artery Disease; Disease Models, Animal; Flax; Glucosides; Humans; Phytotherapy; Rabbits | 2016 |
[The enhancement of protein degradation systems exerts therapeutic effects in the polyglutamine-mediated motor neuron disease].
Topics: Androgen Antagonists; Animals; Autophagy; Disease Models, Animal; Glucosides; Gonadotropin-Releasing Hormone; Humans; Leuprolide; Mice; Molecular Chaperones; Molecular Targeted Therapy; Monoterpenes; Motor Neuron Disease; Muscular Disorders, Atrophic; Peptides; Phytotherapy; Proteolysis | 2016 |
Biological Activities of 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside in Antiaging and Antiaging-Related Disease Treatments.
Topics: Aging; Animals; Cardiovascular Agents; Cellular Senescence; Disease Models, Animal; Drugs, Chinese Herbal; Fallopia multiflora; Gene Expression Regulation; Glucosides; Humans; Hypoglycemic Agents; Neuroprotective Agents; Phytotherapy; Plants, Medicinal; Signal Transduction; Stilbenes | 2016 |
Impact of 2, 3, 5, 4'-tetrahydroxystilbene-2-O-β-D-glucoside on cognitive deficits in animal models of Alzheimer's disease: a systematic review.
Topics: Alzheimer Disease; Animals; Cognition; Disease Models, Animal; Glucosides; Humans; Mice; Rats; Stilbenes | 2016 |
[SGLT inhibitor (T-1095)].
Topics: Animals; Carbonates; Diabetes Mellitus; Disease Models, Animal; Drug Design; Energy Metabolism; Glucose; Glucosides; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Secretion; Kidney; Monosaccharide Transport Proteins | 2002 |
Willow bark extract: the contribution of polyphenols to the overall effect.
Topics: Animals; Arthritis; Back Pain; Benzyl Alcohols; Cells, Cultured; Disease Models, Animal; Drug Compounding; Flavonoids; Glucosides; Humans; Mice; Phenols; Phytotherapy; Plant Bark; Plant Extracts; Polyphenols; Rats; Salix; Time Factors | 2007 |
4 trial(s) available for glucose, (beta-d)-isomer and Disease Models, Animal
| Article | Year |
|---|---|
Dapagliflozin reduces the vulnerability of rats with pulmonary arterial hypertension-induced right heart failure to ventricular arrhythmia by restoring calcium handling.
Topics: Animals; Arrhythmias, Cardiac; Benzhydryl Compounds; Calcium; Connexin 43; Disease Models, Animal; Fura-2; Glucose; Glucosides; Heart Failure; Monocrotaline; Pulmonary Arterial Hypertension; Rats; Sodium; Ventricular Dysfunction, Right; Ventricular Remodeling | 2022 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; Delivery, Obstetric; Denitrification; Dental Caries; Denture, Complete; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dielectric Spectroscopy; Diet, High-Fat; Dietary Fiber; Disease Models, Animal; Disease Progression; DNA; DNA Copy Number Variations; DNA, Mitochondrial; Dog Diseases; Dogs; Dopaminergic Neurons; Double-Blind Method; Down-Regulation; Doxorubicin; Drug Carriers; Drug Design; Drug Interactions; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Dry Powder Inhalers; Dust; E2F1 Transcription Factor; Ecosystem; Education, Nursing; Education, Nursing, Baccalaureate; Electric Impedance; Electricity; Electrocardiography; Electrochemical Techniques; Electrochemistry; Electrodes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endothelial Cells; Environmental Monitoring; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Estrogen Receptor Modulators; Europe; Evoked Potentials, Auditory, Brain Stem; Exosomes; Feasibility Studies; Female; Ferricyanides; Ferrocyanides; Fibrinogen; Finite Element Analysis; Fistula; Fluorescent Dyes; Fluorides, Topical; Fluorodeoxyglucose F18; Fluticasone; Follow-Up Studies; Food Contamination; Food Microbiology; Foods, Specialized; Forensic Medicine; Frail Elderly; France; Free Radicals; Fresh Water; Fungi; Fungicides, Industrial; Galactosamine; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Hemorrhage; Glioblastoma; Glioma; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Glutamine; Glycolysis; Gold; GPI-Linked Proteins; Gram-Negative Bacteria; Gram-Positive Bacteria; Graphite; Haplotypes; HCT116 Cells; Healthy Volunteers; Hearing Loss; Heart Failure; Hedgehog Proteins; HEK293 Cells; HeLa Cells; Hemodynamics; Hemorrhage; Hepatocytes; Hippo Signaling Pathway; Histone Deacetylases; Homeostasis; Hospital Mortality; Hospitalization; Humans; Hydantoins; Hydrazines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hydroxylamines; Hypoglycemic Agents; Immunity, Innate; Immunoglobulin G; Immunohistochemistry; Immunologic Factors; Immunomodulation; Immunophenotyping; Immunotherapy; Incidence; Indazoles; Indonesia; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery; Inflammation; Injections, Intramuscular; Insecticides; Insulin-Like Growth Factor I; Insurance, Health; Intention to Treat Analysis; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Intrauterine Devices; Intrauterine Devices, Copper; Iron; Ischemia; Jordan; Keratinocytes; Kidney; Kidney Diseases; Kir5.1 Channel; Klebsiella Infections; Klebsiella pneumoniae; Lab-On-A-Chip Devices; Laparoscopy; Lasers; Lasers, Semiconductor; Lenalidomide; Leptin; Lethal Dose 50; Levonorgestrel; Limit of Detection; Lipid Metabolism; Lipid Metabolism Disorders; Lipogenesis; Lipopolysaccharides; Liquid Biopsy; Liver; Liver Abscess, Pyogenic; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Longevity; Lung Neoplasms; Luteolin; Lymph Nodes; Lymphocyte Activation; Macaca fascicularis; Macrophages; Mad2 Proteins; Magnetic Resonance Imaging; Male; Mammary Glands, Human; Manganese; Manganese Compounds; MAP Kinase Signaling System; Materials Testing; Maternal Health Services; MCF-7 Cells; Medicaid; Medicine, Chinese Traditional; Melanoma; Membrane Proteins; Mental Health; Mercury; Metal Nanoparticles; Metals, Heavy; Metformin; Methionine Adenosyltransferase; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Nude; Microalgae; Microbial Sensitivity Tests; Microglia; MicroRNAs; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mitochondria; Mitochondrial Proteins; Mitral Valve; Mitral Valve Insufficiency; Models, Anatomic; Molecular Structure; Molybdenum; Monocarboxylic Acid Transporters; Moths; MPTP Poisoning; Multigene Family; Multiparametric Magnetic Resonance Imaging; Multiple Myeloma; Muscle, Skeletal; Mutagens; Mutation; Myeloid Cells; Nanocomposites; Nanofibers; Nanomedicine; Nanoparticles; Nanowires; Neoadjuvant Therapy; Neomycin; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Neostriatum; Neovascularization, Pathologic; Netherlands; Neuromuscular Agents; Neurons; NF-E2-Related Factor 2; NF-kappa B; Nickel; Nitrogen Oxides; Non-alcoholic Fatty Liver Disease; Nucleosides; Nucleotidyltransferases; Nutritional Status; Obesity, Morbid; Ofloxacin; Oils, Volatile; Oligopeptides; Oncogene Protein v-akt; Optical Imaging; Organic Cation Transport Proteins; Organophosphonates; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteoblasts; Osteogenesis; Oxidation-Reduction; Oxidative Stress; Oxides; Oxygen Isotopes; Pancreas; Pancreaticoduodenectomy; Pandemics; Particle Size; Particulate Matter; Patient Acceptance of Health Care; Patient Compliance; PC-3 Cells; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Peroxides; Peru; Pest Control, Biological; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phylogeny; Pilot Projects; Piperidines; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Platelet Function Tests; Pneumonia, Viral; Podocytes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Terephthalates; Polymers; Polymorphism, Single Nucleotide; Porosity; Portugal; Positron-Emission Tomography; Postoperative Complications; Postural Balance; Potassium Channels, Inwardly Rectifying; Povidone; Powders; Precancerous Conditions; Precision Medicine; Predictive Value of Tests; Pregnancy; Prenatal Care; Prognosis; Promoter Regions, Genetic; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Proteasome Inhibitors; Protective Agents; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Psychiatric Nursing; PTEN Phosphohydrolase; Pulmonary Embolism; Pyrimethamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Recombinational DNA Repair; Recovery of Function; Regional Blood Flow; Renal Dialysis; Renin; Renin-Angiotensin System; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Distress Syndrome; Retrospective Studies; Rhodamines; Risk Assessment; Risk Factors; RNA, Long Noncoding; RNA, Messenger; Running; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Salmeterol Xinafoate; Sarcoma; Seasons; Shoulder Injuries; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Sirtuins; Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses | 2021 |
Effects of Cornus mas L. and Morus rubra L. extracts on penicillin-induced epileptiform activity: an electrophysiological and biochemical study.
Topics: Action Potentials; Animals; Anti-Bacterial Agents; Anticonvulsants; Brain Waves; Cerebral Cortex; Disease Models, Animal; Epilepsy; Erythrocytes; Glucosides; Male; Morus; Neurons; Nitric Oxide; Penicillins; Plant Extracts; Pyrans; Rats; Rats, Wistar; Superoxide Dismutase; Thiazolidinediones; Time Factors | 2017 |
Dapagliflozin in focal segmental glomerulosclerosis: a combined human-rodent pilot study.
Topics: Adult; Animals; Arterioles; Benzhydryl Compounds; Disease Models, Animal; Female; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucosides; Humans; Kidney; Male; Middle Aged; Pilot Projects; Proof of Concept Study; Proteinuria; Rats, Sprague-Dawley; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Time Factors; Treatment Outcome; Vasoconstriction | 2018 |
915 other study(ies) available for glucose, (beta-d)-isomer and Disease Models, Animal
| Article | Year |
|---|---|
A porcine model of hemodialyzer reactions: roles of complement activation and rinsing back of extracorporeal blood.
Topics: Animals; Biomarkers; Cellulose; Complement Activation; Disease Models, Animal; Drug-Related Side Effects and Adverse Reactions; Hemodynamics; Hypersensitivity; Membranes, Artificial; Polymers; Renal Dialysis; Sulfones; Swine; Zymosan | 2021 |
Expression of Toll-like receptor 2, Dectin-1, and Osteopontin in murine model of pulpitis.
Topics: Animals; Dental Pulp; Disease Models, Animal; Inflammation; Mice; Osteopontin; Pulpitis; Toll-Like Receptor 2; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha; Zymosan | 2023 |
Potential anti-arthritic and analgesic properties of essential oil and viridiflorol obtained from Allophylus edulis leaves in mice.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Dexamethasone; Dihydroxyphenylalanine; Disease Models, Animal; Edema; Formaldehyde; Headache; Hyperalgesia; Inflammation; Mice; Morphine Derivatives; Oils, Volatile; Plant Extracts; Toothache; Tumor Necrosis Factor-alpha; Zymosan | 2023 |
Analgesic and anti-inflammatory potential of ethanolic extract from Serjania erecta leaves.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; BCG Vaccine; Carrageenan; Disease Models, Animal; Edema; Ethanol; Formaldehyde; Hyperalgesia; Mice; Peritonitis; Plant Extracts; Pleurisy; Sapindaceae; Zymosan | 2023 |
Stattic alleviates pulmonary fibrosis in a mouse model of rheumatoid arthritis-relevant interstitial lung disease.
Topics: Animals; Arthritis, Rheumatoid; Collagen; Disease Models, Animal; Female; Humans; Lung Diseases, Interstitial; Mice; Pulmonary Fibrosis; Transforming Growth Factor beta1; Zymosan | 2023 |
Zymosan A produces a rapid and sustained antidepressant effect in chronically stressed mice by stimulating hippocampal microglia.
Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Hippocampus; Mice; Microglia; Stress, Psychological; Swimming; Zymosan | 2023 |
Discovery of Orexant and Anorexant Agents with Indazole Scaffold Endowed with Peripheral Antiedema Activity.
Topics: Animals; Disease Models, Animal; Edema; Feeding Behavior; Indazoles; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Molecular Structure; Rats; Receptors, Cannabinoid; Rimonabant; Valine; Zymosan | 2019 |
Tannic acid-based nanogel as an efficient anti-inflammatory agent.
Topics: Animals; Anti-Inflammatory Agents; Boronic Acids; Cell Line; Cytokines; Disease Models, Animal; Female; Mice; Nanogels; Neutrophils; Peritonitis; Reactive Oxygen Species; Tannins; Zymosan | 2020 |
FC-99 reduces macrophage tenascin-C expression by upregulating miRNA-494 in arthritis.
Topics: Alkanesulfonates; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Disease Models, Animal; Fluorocarbons; Gene Expression Regulation; Humans; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Signal Transduction; Tenascin; Zymosan | 2020 |
Lycopene used as Anti-inflammatory Nanodrug for the Treatment of Rheumathoid Arthritis: Animal assay, Pharmacokinetics, ABC Transporter and Tissue Deposition.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; ATP-Binding Cassette Transporters; Disease Models, Animal; Dose-Response Relationship, Drug; Lycopene; Male; Mice; Mice, Inbred C57BL; Nanoparticles; Structure-Activity Relationship; Zymosan | 2020 |
Hesperidin methyl chalcone interacts with NFκB Ser276 and inhibits zymosan-induced joint pain and inflammation, and RAW 264.7 macrophage activation.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Arthralgia; Arthritis, Experimental; Cell Line; Chalcones; Cytokines; Disease Models, Animal; Edema; Hesperidin; Inflammation; Macrophage Activation; Macrophages; Mice; Molecular Docking Simulation; NF-kappa B; Oxidative Stress; RAW 264.7 Cells; Signal Transduction; Zymosan | 2020 |
The pterocarpanquinone LQB 118 inhibits inflammation triggered by zymosan in vivo and in vitro.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cells, Cultured; Cytokines; Disease Models, Animal; Female; Humans; Inflammation; Inflammation Mediators; Macrophages; Mice; Naphthoquinones; Peritoneum; Peritonitis; Pterocarpans; Zymosan | 2020 |
Acetylated Polysaccharides From
Topics: Acetylation; Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Fungal Polysaccharides; Gene Expression Regulation; Male; Mice; NF-kappa B; Oxidative Stress; Pleurotus; Signal Transduction; Zymosan | 2020 |
Teasing the Immune System to Repair the Heart.
Topics: Animals; Cell- and Tissue-Based Therapy; Disease Models, Animal; Heart Failure; Immune System; Leukocytes, Mononuclear; Mesenchymal Stem Cell Transplantation; Mice; Reperfusion Injury; Zymosan | 2020 |
Enhanced orbital adipogenesis in a mouse model of T-cell-mediated autoimmunity, zymosan A-treated SKG mice: Implications for Graves' ophthalmopathy.
Topics: Adipocytes; Adipogenesis; Animals; Autoimmunity; Cytokines; Disease Models, Animal; Exophthalmos; Graves Ophthalmopathy; Inflammation; Magnetic Resonance Imaging; Mice; Mice, Inbred BALB C; Orbit; Receptors, Thyrotropin; RNA; T-Lymphocytes; Zymosan | 2020 |
Sulfated polysaccharide from Gracilaria caudata reduces hypernociception and inflammatory response during arthritis in rodents.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Biomarkers; Capillary Permeability; Disease Models, Animal; Edema; Freund's Adjuvant; Gracilaria; Immunohistochemistry; Male; Mice; Polysaccharides; Rodentia; Sulfates; Zymosan | 2020 |
Synthesis and structure-activity relationships of novel 5-(hydroxamic acid)methyl oxazolidinone derivatives as 5-lipoxygenase inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Hydroxamic Acids; Inflammation; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred BALB C; Molecular Structure; Oxazolidinones; Structure-Activity Relationship; Zymosan | 2020 |
Does Training Innate Immunity Confer Broad-spectrum Protection Against Bone and Joint Infection in a Mouse Model?
Topics: Animals; Bone Diseases, Infectious; Disease Models, Animal; Female; Immunity, Innate; Joint Diseases; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Zymosan | 2020 |
Mice Deficient in NOX2 Display Severe Thymic Atrophy, Lymphopenia, and Reduced Lymphopoiesis in a Zymosan-Induced Model of Systemic Inflammation.
Topics: Animals; Atrophy; Disease Models, Animal; Dose-Response Relationship, Drug; Granulomatous Disease, Chronic; Lymphopenia; Lymphopoiesis; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; Systemic Inflammatory Response Syndrome; Thymus Gland; Zymosan | 2021 |
Morita-Baylis-Hillman Adduct 2-(3-Hydroxy-2-oxoindolin-3-yl)acrylonitrile (ISACN) Modulates Inflammatory Process In vitro and In vivo.
Topics: Acrylonitrile; Animals; Anti-Inflammatory Agents; Cell Movement; Cells, Cultured; Cytokines; Disease Models, Animal; Female; Inflammation Mediators; Macrophages, Peritoneal; Mice; Neutrophil Infiltration; Neutrophils; Peritonitis; Zymosan | 2021 |
Analgesic and anti-inflammatory articular effects of essential oil and camphor isolated from Ocimum kilimandscharicum Gürke leaves.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthralgia; Camphor; Carrageenan; Disease Models, Animal; Edema; Hyperalgesia; Inflammation; Joints; Knee Injuries; Leukocyte Rolling; Leukocytes; Male; Mice; Neutrophils; Nitric Oxide; Ocimum; Oils, Volatile; Plant Leaves; Synovial Fluid; Zymosan | 2021 |
Anti-nociceptive effect of
Topics: Analgesics; Animals; Arthritis; Cytokines; Disease Models, Animal; Down-Regulation; Ethanol; Humans; Inflammation Mediators; Male; Mice; NF-E2-Related Factor 2; NLR Family, Pyrin Domain-Containing 3 Protein; Nociceptors; Oxidative Stress; Plant Extracts; Portulaca; Zymosan | 2021 |
Bacterial and Fungal Toll-Like Receptor Activation Elicits Type I IFN Responses in Mast Cells.
Topics: Animals; Cells, Cultured; Chymases; Diphtheria Toxin; Disease Models, Animal; Female; Inflammation; Interferon Type I; Lipopolysaccharides; Macrophages; Male; Mast Cells; Mice, Inbred C57BL; Mice, Transgenic; Neutrophils; Phagocytosis; Signal Transduction; Toll-Like Receptors; Zymosan | 2020 |
The impact of environmental enrichment on the murine inflammatory immune response.
Topics: Animals; Cecum; Disease Models, Animal; Environment; Inflammation; Ligation; Macrophages; Male; Mice; Microarray Analysis; Neutrophils; Peritonitis; Phagocytosis; Sepsis; Zymosan | 2017 |
Administration of Wasabia koreana Ameliorates Irritable Bowel Syndrome-Like Symptoms in a Zymosan-Induced Mouse Model.
Topics: Animals; Colon; Disease Models, Animal; Humans; Irritable Bowel Syndrome; Male; Mice; Mice, Inbred C57BL; Plant Extracts; Tumor Necrosis Factor-alpha; Wasabia; Zymosan | 2017 |
Low-intensity laser therapy efficacy evaluation in FVB mice subjected to acute and chronic arthritis.
Topics: Acute Disease; Animals; Arthritis, Experimental; Cartilage, Articular; Cattle; Chronic Disease; Collagen Type II; Disease Models, Animal; Freund's Adjuvant; Immunohistochemistry; Knee Joint; Low-Level Light Therapy; Male; Mice; Zymosan | 2017 |
Apoptosis inhibitor of macrophage ameliorates fungus-induced peritoneal injury model in mice.
Topics: Animals; Apoptosis Regulatory Proteins; Biomarkers; Complement Activation; Disease Models, Animal; Epithelial Cells; Humans; Macrophages; Mice, Mutant Strains; Peritoneal Dialysis; Peritoneum; Peritonitis; Phagocytosis; Receptors, Immunologic; Receptors, Scavenger; Recombinant Proteins; Scavenger Receptors, Class B; Zymosan | 2017 |
Inflammatory pain assessment in the arthritis of the temporomandibular joint in rats: A comparison between two phlogistic agents.
Topics: Animals; Arthritis; Carrageenan; Disease Models, Animal; Hyperalgesia; Injections, Intra-Articular; Macrophages; Male; Microglia; Nociception; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Rats, Wistar; Temporomandibular Joint Disorders; Trigeminal Ganglion; Zymosan | 2017 |
CD11b+Gr-1
Topics: Adoptive Transfer; Animals; CD11b Antigen; Cell Differentiation; Cell Proliferation; Coculture Techniques; Dendritic Cells; Disease Models, Animal; Flow Cytometry; Fluoresceins; Granulocyte-Macrophage Colony-Stimulating Factor; Interleukin-4; Lung; Lung Diseases, Interstitial; Mice; Myeloid-Derived Suppressor Cells; Receptors, Chemokine; Succinimides; T-Lymphocytes; Th17 Cells; Zymosan | 2017 |
Transgenic Mice Expressing Human Proteinase 3 Exhibit Sustained Neutrophil-Associated Peritonitis.
Topics: Animals; Annexin A1; Apoptosis; Disease Models, Animal; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myeloblastin; Neutrophils; Peritoneal Cavity; Peritonitis; Phagocytosis; Sepsis; Zymosan | 2017 |
Protection by mTOR Inhibition on Zymosan-Induced Systemic Inflammatory Response and Oxidative/Nitrosative Stress: Contribution of mTOR/MEK1/ERK1/2/IKKβ/IκB-α/NF-κB Signalling Pathway.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arterial Pressure; Cyclooxygenase 2; Cytokines; Disease Models, Animal; I-kappa B Proteins; Inflammation; Inflammation Mediators; Male; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase Type II; Nitrosative Stress; Oxidative Stress; Phosphorylation; Protein Kinase Inhibitors; Rats, Wistar; Signal Transduction; Sirolimus; Time Factors; TOR Serine-Threonine Kinases; Vasodilation; Zymosan | 2018 |
Agonistic activity of tamoxifen, a selective estrogen-receptor modulator (SERM), on arthritic ovariectomized mice.
Topics: Animals; Arthritis, Experimental; Cell Migration Assays, Leukocyte; Cell Movement; Disease Models, Animal; Estrogen Antagonists; Estrous Cycle; Female; Mice; Neutrophils; Organ Size; Ovariectomy; Random Allocation; Reproducibility of Results; Selective Estrogen Receptor Modulators; Tamoxifen; Time Factors; Treatment Outcome; Uterus; Zymosan | 2017 |
Spondyloarthritis features in zymosan-induced SKG mice.
Topics: Animals; Arthritis, Experimental; beta-Glucans; Biopsy, Needle; Cytokines; Disease Models, Animal; Humans; Imaging, Three-Dimensional; Immunohistochemistry; Injections, Intraperitoneal; Interleukin-17; Interleukin-6; Mice; Mice, Inbred Strains; Positron Emission Tomography Computed Tomography; Random Allocation; Sensitivity and Specificity; Spondylarthritis; Zymosan | 2018 |
Tacrolimus interacts with voriconazole to reduce the severity of fungal keratitis by suppressing IFN-related inflammatory responses and concomitant FK506 and voriconazole treatment suppresses fungal keratitis.
Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Cornea; Disease Models, Animal; Drug Combinations; Drug Synergism; Epithelial Cells; Eye Infections, Fungal; Female; Gene Expression Regulation; Interferons; Interleukins; Keratitis; Lymphocytes; Macrophages; Mice; Mice, Inbred C57BL; Neutrophils; Severity of Illness Index; Tacrolimus; Voriconazole; Zymosan | 2018 |
TNF and granulocyte macrophage-colony stimulating factor interdependence mediates inflammation via CCL17.
Topics: Animals; Antibodies, Monoclonal; Arthritis, Rheumatoid; Chemokine CCL17; Cytokines; Disease Models, Animal; Female; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Inflammation; Interferon Regulatory Factors; Jumonji Domain-Containing Histone Demethylases; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pain; Tumor Necrosis Factor-alpha; Zymosan | 2018 |
LOX-1 deficient mice show resistance to zymosan-induced arthritis.
Topics: Animals; Arthritis; Disease Models, Animal; Disease Resistance; Gene Deletion; Gene Knockout Techniques; Immunohistochemistry; Knee Joint; Mice; Scavenger Receptors, Class E; Synovial Fluid; Zymosan | 2018 |
Myeloid Heme Oxygenase-1 Regulates the Acute Inflammatory Response to Zymosan in the Mouse Air Pouch.
Topics: Acute Disease; Animals; Disease Models, Animal; Heme Oxygenase-1; Inflammation; Macrophages, Peritoneal; Male; Matrix Metalloproteinase 3; Membrane Proteins; Mice; Mice, Knockout; Neutrophils; Zymosan | 2018 |
The oxidized linoleic acid metabolite 12,13-DiHOME mediates thermal hyperalgesia during inflammatory pain.
Topics: Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Enzyme Inhibitors; Epoxide Hydrolases; Female; Freund's Adjuvant; Hot Temperature; Humans; Hyperalgesia; Inflammation; Linoleic Acid; Male; Mice; Oleic Acids; Oxidation-Reduction; Pain; Phenylurea Compounds; Piperidines; Protein Kinase C; Sensory Receptor Cells; TRPV Cation Channels; Zymosan | 2018 |
The Bisindole Alkaloid Caulerpin, from Seaweeds of the Genus
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Caulerpa; Colitis, Ulcerative; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Indoles; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Peritonitis; Seaweed; Treatment Outcome; Zymosan | 2018 |
Hematopoietic Stem/Progenitor Cell Dependent Participation of Innate Lymphoid Cells in Low-Intensity Sterile Inflammation.
Topics: Animals; Bone Marrow Cells; Cell Differentiation; Cell Movement; Cell Self Renewal; Cells, Cultured; Disease Models, Animal; Female; Hematopoietic Stem Cells; Humans; Immunity, Innate; Lymphocytes; Mice; Mice, Inbred C57BL; Peritonitis; Signal Transduction; Stem Cell Niche; Zymosan | 2018 |
Anti-C5a complementary peptide mitigates zymosan-induced severe peritonitis with fibrotic encapsulation in rats pretreated with methylglyoxal.
Topics: Animals; Complement Activation; Complement C5a; Complement Inactivating Agents; Disease Models, Animal; Disease Progression; Male; Peritoneal Fibrosis; Peritoneum; Peritonitis; Pyruvaldehyde; Rats, Sprague-Dawley; Severity of Illness Index; Signal Transduction; Time Factors; Zymosan | 2018 |
Alleviation of Irritable Bowel Syndrome-Like Symptoms and Control of Gut and Brain Responses with Oral Administration of
Topics: Administration, Oral; Animals; Anxiety; Brain; Colon; Disease Models, Animal; Dolichos; Irritable Bowel Syndrome; Male; Mice; Mice, Inbred C57BL; Phytotherapy; Plant Extracts; Zymosan | 2018 |
NF-κB activation mediates LPS-or zymosan-induced hypotension and inflammation reversed by BAY61-3606, a selective Syk inhibitor, in rat models of septic and non-septic shock.
Topics: Animals; Cyclooxygenase 2; Disease Models, Animal; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Hypotension; Inflammation; Interleukin-8; Lipopolysaccharides; Male; NF-kappa B; NF-KappaB Inhibitor alpha; Niacinamide; Nitric Oxide Synthase Type II; Protein Kinase Inhibitors; Pyrimidines; Rats; Rats, Wistar; Shock, Septic; Syk Kinase; Tumor Necrosis Factor-alpha; Zymosan | 2019 |
Discordant susceptibility of inbred C57BL/6 versus outbred CD1 mice to experimental fungal sepsis.
Topics: Animals; Animals, Outbred Strains; Bacterial Outer Membrane Proteins; Candida albicans; Candidiasis; CD5 Antigens; Cytokines; Disease Models, Animal; Disease Susceptibility; Interferon-gamma; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mycoses; Sepsis; Species Specificity; Spleen; Teichoic Acids; Zymosan | 2019 |
The citrus flavanone naringenin attenuates zymosan-induced mouse joint inflammation: induction of Nrf2 expression in recruited CD45
Topics: Animals; Arthritis; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Flavanones; Hematopoietic Stem Cells; Inflammasomes; Knee Joint; Leukocyte Common Antigens; Male; Mice; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Signal Transduction; Zymosan | 2019 |
Effects of CPEB1 in the anterior cingulate cortex on visceral pain in mice.
Topics: Animals; Anxiety; Disease Models, Animal; Gyrus Cinguli; Male; Mice; Mice, Inbred C57BL; mRNA Cleavage and Polyadenylation Factors; Receptors, AMPA; RNA, Messenger; Synaptophysin; Transcription Factors; Visceral Pain; Zymosan | 2019 |
Macrophage-dependent neutrophil recruitment is impaired under conditions of increased intestinal permeability in JAM-A-deficient mice.
Topics: Animals; Cell Adhesion Molecules; Cells, Cultured; Chemokine CXCL1; Disease Models, Animal; Gastrointestinal Microbiome; Humans; Intestinal Mucosa; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Neutrophil Infiltration; Neutrophils; NF-kappa B; Peritonitis; Permeability; Receptors, Cell Surface; Tight Junctions; Zymosan | 2019 |
Alpha lipoic acid and metformin alleviates experimentally induced insulin resistance and cognitive deficit by modulation of TLR2 signalling.
Topics: Animals; Anti-Inflammatory Agents; Cognition Disorders; Disease Models, Animal; Insulin; Insulin Resistance; Interleukin-6; Lipid Peroxidation; Lipids; Male; Maze Learning; Memory; Metformin; Mice; Signal Transduction; Thioctic Acid; Toll-Like Receptor 2; Zymosan | 2019 |
Bacterial translocation in an experimental model of multiple organ dysfunctions.
Topics: Animals; Bacterial Translocation; Disease Models, Animal; Enterobacteriaceae; Enterococcus; Interferon-gamma; Interleukin-10; Interleukin-17; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Multiple Organ Failure; Spleen; Zymosan | 2013 |
Peripheral neural detection of danger-associated and pathogen-associated molecular patterns.
Topics: Animals; Calcium; Carotid Body; Carotid Sinus; Disease Models, Animal; Humans; Inflammation Mediators; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Neutrophils; Random Allocation; Rats; Rats, Sprague-Dawley; Toll-Like Receptors; Zymosan | 2013 |
Three-dimensional evaluation of retinal ganglion cell axon regeneration and pathfinding in whole mouse tissue after injury.
Topics: Adenoviridae; Animals; Axons; Cholera Toxin; Cyclic AMP; Disease Models, Animal; Female; Functional Laterality; Green Fluorescent Proteins; Imaging, Three-Dimensional; Mice; Mice, Transgenic; Microscopy, Fluorescence; Nerve Crush; Nerve Regeneration; Optic Nerve Diseases; PTEN Phosphohydrolase; Retinal Ganglion Cells; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Visual Pathways; Zymosan | 2013 |
Dectin-1 plays a redundant role in the immunomodulatory activities of β-glucan-rich ligands in vivo.
Topics: Animals; Disease Models, Animal; Glucans; Lectins, C-Type; Ligands; Mice; Multiple Organ Failure; Staphylococcal Infections; Staphylococcus aureus; Zymosan | 2013 |
Regulatory T cells are protective in systemic inflammation response syndrome induced by zymosan in mice.
Topics: Animals; Cytokines; Disease Models, Animal; Lung; Lymphocyte Depletion; Male; Mice; Systemic Inflammatory Response Syndrome; T-Lymphocytes, Regulatory; Zymosan | 2013 |
Insulin resistance induced by zymosan as a new animal model in mice.
Topics: Animals; Diabetes Mellitus, Experimental; Diet; Disease Models, Animal; Fructose; Insulin Resistance; Male; Mice; Mice, Inbred BALB C; Prediabetic State; Recovery of Function; Zymosan | 2013 |
Microbiota signalling through MyD88 is necessary for a systemic neutrophilic inflammatory response.
Topics: Animals; Bacteria; Chemokines; Disease Models, Animal; Inflammation Mediators; Intestinal Mucosa; Intestines; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Differentiation Factor 88; Neutrophil Infiltration; Neutrophils; Peritonitis; Receptors, Interleukin-1; Signal Transduction; Toll-Like Receptors; Zymosan | 2013 |
Rat adipose tissue-derived stem cells attenuate peritoneal injuries in rat zymosan-induced peritonitis accompanied by complement activation.
Topics: Adipose Tissue; Animals; Antibody-Dependent Cell Cytotoxicity; Cell Proliferation; Cells, Cultured; Coculture Techniques; Complement Activation; Disease Models, Animal; Hepatocyte Growth Factor; Humans; Injections, Intraperitoneal; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Peritonitis; Rats; Rats, Sprague-Dawley; Yeasts; Zymosan | 2014 |
The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP).
Topics: 5-Lipoxygenase-Activating Protein Inhibitors; 5-Lipoxygenase-Activating Proteins; Animals; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Benzimidazoles; Carrageenan; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Humans; Leukotriene Antagonists; Leukotrienes; Male; Mice; Monocytes; Neutrophils; Peritonitis; Pleurisy; Rats, Wistar; Zymosan | 2014 |
Tephrosia toxicaria Pers. reduces temporomandibular joint inflammatory hypernociception: the involvement of the HO-1 pathway.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Heme Oxygenase-1; Hyperalgesia; Inflammation; Male; Metabolic Networks and Pathways; Mice; Phytotherapy; Plant Preparations; Protoporphyrins; Rats; Rats, Wistar; Temporomandibular Joint Disorders; Tephrosia; Zymosan | 2014 |
NOX2 protects against progressive lung injury and multiple organ dysfunction syndrome.
Topics: Animals; Bone Marrow Cells; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Lung; Lung Injury; Macrophage Activation; Macrophages; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Multiple Organ Failure; NADPH Oxidase 2; NADPH Oxidases; Neutrophil Infiltration; Systemic Inflammatory Response Syndrome; Zymosan | 2014 |
Discovery of structurally simplified analogs of colchicine as an immunosuppressant.
Topics: Animals; Arthritis; B-Lymphocytes; Carrageenan; Cell Proliferation; Colchicine; Concanavalin A; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Edema; Humans; Immunosuppressive Agents; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Molecular Structure; Structure-Activity Relationship; T-Lymphocytes; Zymosan | 2014 |
GM-CSF but not IL-17 is critical for the development of severe interstitial lung disease in SKG mice.
Topics: Animals; Antibodies, Neutralizing; Arthritis; CD4-Positive T-Lymphocytes; Cells, Cultured; Connective Tissue Diseases; Disease Models, Animal; Female; Flow Cytometry; Granulocyte-Macrophage Colony-Stimulating Factor; Interleukin-17; Interleukin-1beta; Interleukin-6; Lung; Lung Diseases, Interstitial; Macrophages; Mice; Mice, Inbred BALB C; Neutrophils; Severity of Illness Index; Th17 Cells; Time Factors; Zymosan | 2014 |
Validation of cyclooxygenase-2 as a direct anti-inflammatory target of 4-O-methylhonokiol in zymosan-induced animal models.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Cyclooxygenase 2; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Female; Inflammation; Lignans; Macrophages; Mice; Mice, Inbred C57BL; Zymosan | 2015 |
Inhibition of mitogen-activated protein kinases phosphorylation plays an important role in the anti-nociceptive effect of pregabalin in zymosan-induced inflammatory pain model.
Topics: Analgesics; Animals; Disease Models, Animal; gamma-Aminobutyric Acid; Male; Mitogen-Activated Protein Kinases; Pain; Pain Measurement; Phosphorylation; Pregabalin; Rats; Rats, Sprague-Dawley; Treatment Outcome; Zymosan | 2014 |
Probiotic Lactobacillus rhamnosus GG (LGG) and prebiotic prevent neonatal inflammation-induced visceral hypersensitivity in adult rats.
Topics: Animals; Animals, Newborn; Brain; Disease Models, Animal; Hyperalgesia; Inflammation; Intestines; Lacticaseibacillus rhamnosus; Manometry; Neurotransmitter Agents; Prebiotics; Probiotics; Rats; Rats, Sprague-Dawley; Visceral Pain; Zymosan | 2014 |
Role of Serotonin in MODS: Deficiency of Serotonin Protects Against Zymosan-Induced Multiple Organ Failure in Mice.
Topics: 5-Hydroxytryptophan; Animals; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Fenclonine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Multiple Organ Failure; Oxidative Stress; Peritonitis; Protective Agents; Serotonin; Shock; Tryptophan Hydroxylase; Zymosan | 2015 |
Oral administration of curcumin (Curcuma longa) can attenuate the neutrophil inflammatory response in zymosan-induced arthritis in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Curcumin; Disease Models, Animal; Male; Neutrophil Infiltration; Neutrophils; Prednisolone; Rats, Wistar; Reproducibility of Results; Severity of Illness Index; Time Factors; Treatment Outcome; Zymosan | 2014 |
Therapeutic Effects of Bone Marrow-Derived Mesenchymal Stem Cells in Models of Pulmonary and Extrapulmonary Acute Lung Injury.
Topics: Acute Lung Injury; Animals; Apoptosis; Bone Marrow Cells; Cell Line; Cell- and Tissue-Based Therapy; Chemokine CXCL12; Disease Models, Animal; HEK293 Cells; Humans; Lipopolysaccharides; Liver; Lung; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Pneumonia; Spleen; Zymosan | 2015 |
Reactive oxygen species mediate visceral pain-related amygdala plasticity and behaviors.
Topics: Amygdala; Animals; Antioxidants; Anxiety; Cyclic N-Oxides; Disease Models, Animal; Electrophysiology; Male; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spin Labels; Synaptic Transmission; Visceral Pain; Vocalization, Animal; Zymosan | 2015 |
Taurine Chloramine Stimulates Efferocytosis Through Upregulation of Nrf2-Mediated Heme Oxygenase-1 Expression in Murine Macrophages: Possible Involvement of Carbon Monoxide.
Topics: Adaptor Proteins, Signal Transducing; Animals; Carbon Monoxide; Cytoskeletal Proteins; Disease Models, Animal; Heme Oxygenase-1; Humans; Inflammation; Jurkat Cells; Kelch-Like ECH-Associated Protein 1; Macrophages; Macrophages, Peritoneal; Mice; NF-E2-Related Factor 2; Phagocytosis; Taurine; Up-Regulation; Zymosan | 2015 |
Cytokines, but not corticotropin-releasing factor and endothelin-1, participate centrally in the febrile response in zymosan-induced arthritis in rats.
Topics: Animals; Arthritis; Body Temperature; Corticotropin-Releasing Hormone; Cytokines; Disease Models, Animal; Endothelin-1; Fever; Hyperalgesia; Male; Rats, Wistar; Zymosan | 2015 |
Nociceptive and inflammatory mediator upregulation in a mouse model of chronic prostatitis.
Topics: Animals; Behavior, Animal; Chronic Disease; Disease Models, Animal; Ganglia, Spinal; Inflammation; Inflammation Mediators; Interleukin-10; Male; Mice; Nerve Growth Factor; Nociceptors; Pain; Potassium Channels, Tandem Pore Domain; Prostate; Prostatitis; Receptors, Purinergic P2X; Tryptases; Up-Regulation; Zymosan | 2015 |
Baroreflex activation in conscious rats modulates the joint inflammatory response via sympathetic function.
Topics: Adrenalectomy; Animals; Arthritis; Baroreflex; Disease Models, Animal; Electric Stimulation; Inflammation; Inflammation Mediators; Knee Joint; Male; Neutrophils; Rats; Rats, Wistar; Splenectomy; Sympathetic Nervous System; Vagotomy; Zymosan | 2015 |
Coenzyme Q10 suppresses Th17 cells and osteoclast differentiation and ameliorates experimental autoimmune arthritis mice.
Topics: Animals; Arthritis, Experimental; Autoantibodies; Autoimmune Diseases; B-Lymphocytes; Bone Resorption; Cell Differentiation; Disease Models, Animal; Germinal Center; Humans; Immunophenotyping; Immunosuppressive Agents; Interleukin-17; Leukocytes, Mononuclear; Mice; Osteoclasts; Spleen; T-Lymphocyte Subsets; Th17 Cells; Ubiquinone; Zymosan | 2015 |
The H2S-producing enzyme CSE is dispensable for the processing of inflammatory and neuropathic pain.
Topics: Animals; Cystathionine gamma-Lyase; Disease Models, Animal; Formaldehyde; Ganglia, Spinal; Gene Expression Regulation; Hydrogen Sulfide; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Neuralgia; Pain Measurement; Spinal Cord; Up-Regulation; Zymosan | 2015 |
Investigation of the relationship between the onset of arthritis and uveitis in genetically predisposed SKG mice.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; beta-Glucans; Disease Models, Animal; Disease Progression; Genetic Predisposition to Disease; Humans; Mice, Inbred BALB C; Mice, Knockout; Mutation, Missense; Severity of Illness Index; T-Lymphocytes; Time Factors; Uveitis; ZAP-70 Protein-Tyrosine Kinase; Zymosan | 2015 |
The role of CNS TLR2 activation in mediating innate versus adaptive neuroinflammation.
Topics: Adaptive Immunity; Animals; CD3 Complex; Cell Proliferation; Central Nervous System; Cytokines; Disease Models, Animal; Encephalitis; Encephalomyelitis, Autoimmune, Experimental; Female; Immunity, Innate; Injections, Intraventricular; Macrophages; Mice; Microglia; Myelin Proteolipid Protein; Peptide Fragments; RNA, Messenger; T-Lymphocytes; Time Factors; Toll-Like Receptor 2; Zymosan | 2015 |
The spinal antinociceptive mechanism determined by systemic administration of BD1047 in zymosan-induced hyperalgesia in rats.
Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ethylenediamines; Hyperalgesia; Male; Microglia; Pain; Posterior Horn Cells; Rats, Sprague-Dawley; Receptors, sigma; Spinal Cord; Zymosan | 2015 |
Long-term upregulation of cortical glutamatergic AMPA receptors in a mouse model of chronic visceral pain.
Topics: Adamantane; Adenylyl Cyclases; Animals; Behavior, Animal; Calcium; Cell Membrane; Chronic Pain; Disease Models, Animal; Excitatory Postsynaptic Potentials; Gene Deletion; Glutamates; Gyrus Cinguli; Injections; Irritable Bowel Syndrome; Mice; Models, Biological; Phosphorylation; Phosphoserine; Protein Transport; Receptors, AMPA; Synaptic Transmission; Time Factors; Up-Regulation; Visceral Pain; Zymosan | 2015 |
Dynamic weight bearing as a non-reflexive method for the measurement of abdominal pain in mice.
Topics: Abdominal Pain; Aniline Compounds; Animals; Behavior, Animal; Celecoxib; Chronic Pain; Cyclooxygenase 2 Inhibitors; Dinoprostone; Disease Models, Animal; Furans; Inflammation; Mice; Pain Measurement; Pelvic Pain; Peritoneal Lavage; Peritonitis; Sodium Channel Blockers; Weight-Bearing; Zymosan | 2016 |
Activation of maternal toll-like receptor-2 causes social deficits and memory impairment in female offspring.
Topics: Animals; Disease Models, Animal; Female; Male; Memory Disorders; Mice, Inbred ICR; Neuropsychological Tests; Pregnancy; Prenatal Exposure Delayed Effects; Recognition, Psychology; Sex Characteristics; Social Behavior; Toll-Like Receptor 2; Zymosan | 2016 |
Comparison of complement activation-related pseudoallergy in miniature and domestic pigs: foundation of a validatable immune toxicity model.
Topics: Amphotericin B; Animals; Complement Activation; Disease Models, Animal; Doxorubicin; Drug Hypersensitivity; Glycerol; Humans; Liposomes; Nanomedicine; Nanoparticles; Polyethylene Glycols; Swine; Swine, Miniature; Zymosan | 2016 |
Inhibition of CRMP2 phosphorylation repairs CNS by regulating neurotrophic and inhibitory responses.
Topics: Animals; Axons; Brain-Derived Neurotrophic Factor; Cells, Cultured; Central Nervous System; Chondroitin Sulfate Proteoglycans; Disease Models, Animal; Ganglia, Spinal; Gene Expression Regulation; Hindlimb; Intercellular Signaling Peptides and Proteins; Mice; Mice, Transgenic; Microtubules; Motor Disorders; Mutation; Nerve Tissue Proteins; Neurons; Phosphorylation; Spinal Cord Injuries; Zymosan | 2016 |
Subanesthetic isoflurane relieves zymosan-induced neutrophil inflammatory response by targeting NMDA glutamate receptor and Toll-like receptor 2 signaling.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Capillary Permeability; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Isoflurane; Lung; Mice; Nerve Tissue Proteins; Neutrophils; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Peroxynitrous Acid; Pneumonia; Receptors, N-Methyl-D-Aspartate; RNA Interference; Signal Transduction; src-Family Kinases; Time Factors; Toll-Like Receptor 2; Transfection; Zymosan | 2016 |
Interfering with the CCL2-glycosaminoglycan axis as a potential approach to modulate neuroinflammation.
Topics: Animals; Anti-Inflammatory Agents; Cerebellum; Chemokine CCL2; Dexamethasone; Disease Models, Animal; Encephalitis; Encephalomyelitis, Autoimmune, Experimental; Female; Glycosaminoglycans; Inhibitory Concentration 50; Male; Mice; Mice, Inbred C57BL; Monocytes; Myelin-Oligodendrocyte Glycoprotein; Peptide Fragments; Peritonitis; Spinal Cord; Zymosan | 2016 |
Zymosan-Induced Peritonitis: Effects on Cardiac Function, Temperature Regulation, Translocation of Bacteria, and Role of Dectin-1.
Topics: Alarmins; Animals; Disease Models, Animal; Inflammation; Lectins, C-Type; Male; Mice; Mice, Knockout; Multiple Organ Failure; Peritonitis; Receptors, Pattern Recognition; Zymosan | 2016 |
Crotalphine desensitizes TRPA1 ion channels to alleviate inflammatory hyperalgesia.
Topics: Action Potentials; Analgesics; Animals; Bradykinin; Calcium; Cells, Cultured; Disease Models, Animal; Ganglia, Spinal; HEK293 Cells; Humans; Hyperalgesia; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neurons; Peptides; Transient Receptor Potential Channels; TRPA1 Cation Channel; Zymosan | 2016 |
Aqueous extract from Ipomoea asarifolia (Convolvulaceae) leaves and its phenolic compounds have anti-inflammatory activity in murine models of edema, peritonitis and air-pouch inflammation.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Chemotaxis, Leukocyte; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Female; Inflammation; Inflammation Mediators; Ipomoea; Leukocyte Count; Leukocytes; Male; Mass Spectrometry; Mice, Inbred BALB C; Peritonitis; Phenols; Phytotherapy; Plant Extracts; Plant Leaves; Plants, Medicinal; Time Factors; Xylenes; Zymosan | 2016 |
PKA regulatory IIα subunit is essential for PGD2-mediated resolution of inflammation.
Topics: Animals; Cecum; Cell Polarity; Cyclic AMP-Dependent Protein Kinase RIIalpha Subunit; Disease Models, Animal; Female; Gene Deletion; Hydantoins; Inflammation; Janus Kinase 2; Ligation; Macrophages; Mice, Inbred C57BL; Myocardial Infarction; Myocardial Ischemia; Peritonitis; Prostaglandin D2; Protein Binding; Protein Subunits; Punctures; Receptors, Immunologic; Receptors, Interferon; Receptors, Prostaglandin; Signal Transduction; STAT1 Transcription Factor; Wound Healing; Zymosan | 2016 |
Galectin-3-null mice display defective neutrophil clearance during acute inflammation.
Topics: Acute Disease; Animals; Apoptosis; Cell Membrane; Cytosol; Disease Models, Animal; Galectin 3; Inflammation; Male; Mice, Inbred C57BL; Neutrophils; Peritonitis; Zymosan | 2017 |
DEK-targeting DNA aptamers as therapeutics for inflammatory arthritis.
Topics: Adult; Animals; Aptamers, Nucleotide; Arthritis, Juvenile; Chemotactic Factors; Chromosomal Proteins, Non-Histone; Disease Models, Animal; DNA-Binding Proteins; Extracellular Traps; Female; Healthy Volunteers; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Oncogene Proteins; Poly-ADP-Ribose Binding Proteins; Primary Cell Culture; Synovial Fluid; Zymosan | 2017 |
Scintigraphic imaging using technetium-99m-labeled ceftizoxime in an experimental model of acute osteomyelitis in rats.
Topics: Animals; Blood Proteins; Ceftizoxime; Disease Models, Animal; Inflammation; Male; Organotechnetium Compounds; Osteomyelitis; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Wistar; Sepsis; Staphylococcal Infections; Time Factors; Zymosan | 2008 |
Functional imaging of interleukin 1 beta expression in inflammatory process using bioluminescence imaging in transgenic mice.
Topics: Animals; Dexamethasone; Disease Models, Animal; Gene Expression; Interleukin-1beta; Lipopolysaccharides; Luciferases, Firefly; Luminescent Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Promoter Regions, Genetic; Rheumatic Fever; Sepsis; Transcriptional Activation; Zymosan | 2008 |
The anti-arthritic effect of ursolic acid on zymosan-induced acute inflammation and adjuvant-induced chronic arthritis models.
Topics: Acute Disease; Animals; Antirheumatic Agents; Arthritis, Experimental; Cell Movement; Chronic Disease; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation; Leukocytes; Mice; Mice, Inbred ICR; Oldenlandia; Pain; Plant Extracts; Rats; Rats, Sprague-Dawley; Triterpenes; Ursolic Acid; Zymosan | 2008 |
COX-2 expression and function in the hyperalgesic response to paw inflammation in mice.
Topics: Animals; Blotting, Western; Brain; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Disease Models, Animal; Edema; Gene Expression Regulation, Enzymologic; Hindlimb; Hyperalgesia; Inflammation; Isoxazoles; Mice; Mice, Inbred C57BL; Mice, Knockout; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord; Zymosan | 2008 |
Possible mechanism of the anti-inflammatory activity of ruscogenin: role of intercellular adhesion molecule-1 and nuclear factor-kappaB.
Topics: Active Transport, Cell Nucleus; Animals; Anti-Inflammatory Agents; Cell Line; Cell Movement; Dinoprostone; Disease Models, Animal; DNA; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Intercellular Adhesion Molecule-1; Leukocytes; Male; Mice; Mice, Inbred ICR; Ophiopogon; Peritonitis; Plant Tubers; RNA, Messenger; Spirostans; Transcription Factor RelA; Tumor Necrosis Factor-alpha; Zymosan | 2008 |
100% oxygen inhalation protects against zymosan-induced sterile sepsis in mice: the roles of inflammatory cytokines and antioxidant enzymes.
Topics: Administration, Inhalation; Animals; Catalase; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Glutathione Peroxidase; Interleukin-10; Interleukin-6; Male; Mice; Oxidoreductases; Oxygen; Sepsis; Superoxide Dismutase; Time Factors; Tumor Necrosis Factor-alpha; Zymosan | 2009 |
In vitro and in vivo modulation of cartilage degradation by a standardized Centella asiatica fraction.
Topics: Animals; Cartilage; Cattle; Cell Proliferation; Cells, Cultured; Centella; Chondrocytes; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Interleukin-1beta; Mice; Nitric Oxide; Osteoarthritis, Knee; Plant Extracts; Proteoglycans; Triterpenes; Zymosan | 2009 |
Synergism of toll-like receptor 2 (TLR2), TLR4, and TLR6 ligation on the production of tumor necrosis factor (TNF)-alpha in a spontaneous arthritis animal model of interleukin (IL)-1 receptor antagonist-deficient mice.
Topics: Animals; Arthritis, Experimental; Disease Models, Animal; Fibroblasts; Interleukin 1 Receptor Antagonist Protein; Interleukin-10; Interleukin-1beta; Knee Joint; Ligands; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Mice, Knockout; Toll-Like Receptor 2; Toll-Like Receptor 4; Toll-Like Receptor 6; Tumor Necrosis Factor-alpha; Zymosan | 2009 |
Chapter 17. Zymosan-induced peritonitis as a simple experimental system for the study of inflammation.
Topics: Animals; Disease Models, Animal; Inflammation; Mice; Peritonitis; Rats; Zymosan | 2009 |
Peripheral and central P2X receptor contributions to colon mechanosensitivity and hypersensitivity in the mouse.
Topics: Adenosine Triphosphate; Afferent Pathways; Animals; Central Nervous System; Colon; Disease Models, Animal; Hyperalgesia; Inflammation Mediators; Intestinal Mucosa; Irritable Bowel Syndrome; Male; Mechanotransduction, Cellular; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth; Pressure; Receptors, Purinergic P2; Receptors, Purinergic P2X3; Zymosan | 2009 |
Zymosan, but not lipopolysaccharide, triggers severe and progressive peritoneal injury accompanied by complement activation in a rat peritonitis model.
Topics: Animals; Cell Movement; Complement Activation; Complement C3b; Complement Membrane Attack Complex; Disease Models, Animal; Lipopolysaccharides; Male; Neovascularization, Pathologic; Peritoneum; Peritonitis; Rats; Rats, Sprague-Dawley; Yeasts; Zymosan | 2009 |
The effects of L-NG-nitroarginine in a zymosan-induced multiple organ dysfunction syndrome model.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Kidney; Male; Mice; Multiple Organ Failure; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pancreas; Splanchnic Circulation; Zymosan | 2009 |
Total synthesis and bioactivity of resolvin E2.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Eicosapentaenoic Acid; Mice; Neutrophil Infiltration; Peritonitis; Stereoisomerism; Zymosan | 2009 |
Monocyte chemoattractant protein-1 (MCP-1), not MCP-3, is the primary chemokine required for monocyte recruitment in mouse peritonitis induced with thioglycollate or zymosan A.
Topics: Animals; Carboxypeptidases A; Cell Movement; Chemokine CCL2; Disease Models, Animal; Down-Regulation; Gene Deletion; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Peritonitis; Thioglycolates; Up-Regulation; Zymosan | 2009 |
Pharmacological characterization of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103), a novel selective 5-lipoxygenase-activating protein inhibitor that reduces acute
Topics: 5-Lipoxygenase-Activating Proteins; Acute Disease; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Carrier Proteins; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Extravasation of Diagnostic and Therapeutic Materials; Female; Humans; Indoles; Inflammation; Leukotriene B4; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Pneumonia; Propionates; Rats; Rats, Sprague-Dawley; Zymosan | 2009 |
Optic nerve and vitreal inflammation are both RGC neuroprotective but only the latter is RGC axogenic.
Topics: Animals; Astrocytes; Axonal Transport; Cell Communication; Cytoprotection; Disease Models, Animal; Growth Cones; Inflammation; Inflammation Mediators; Male; Nerve Growth Factors; Nerve Regeneration; Optic Neuritis; Rats; Rats, Wistar; Receptor, Nerve Growth Factor; Retina; Retinal Ganglion Cells; rho GTP-Binding Proteins; Signal Transduction; Vitreous Body; Zymosan | 2010 |
Neonatal bladder inflammation produces functional changes and alters neuropeptide content in bladders of adult female rats.
Topics: Aging; Animals; Animals, Newborn; Calcitonin Gene-Related Peptide; Cystitis; Disease Models, Animal; Evans Blue; Female; Irritants; Mustard Plant; Neuropeptides; Nociceptors; Plant Oils; Rats; Sensory Receptor Cells; Substance P; Time; Urinary Bladder; Zymosan | 2010 |
IL-17 mediates articular hypernociception in antigen-induced arthritis in mice.
Topics: Analysis of Variance; Animals; Antibodies, Monoclonal; Antigens; Antirheumatic Agents; Arthritis; Cell Movement; Cytokines; Dinoprostone; Disease Models, Animal; Endothelins; Enzyme Inhibitors; Gene Expression Regulation; Hyperalgesia; Infliximab; Interleukin-17; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Pain Threshold; Polysaccharides; Receptors, Tumor Necrosis Factor, Type I; Serum Albumin; Zymosan | 2010 |
Uncoupling protein-2 negatively regulates polymorphonuclear leukocytes chemotaxis via modulating [Ca2+] influx.
Topics: Animals; Calcium; CD11b Antigen; CD18 Antigens; Cell Movement; Chemotaxis; Cytoplasm; Diabetes Mellitus, Experimental; Disease Models, Animal; Ion Channels; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peritonitis; Streptozocin; Uncoupling Protein 2; Zymosan | 2010 |
Apremilast, a cAMP phosphodiesterase-4 inhibitor, demonstrates anti-inflammatory activity in vitro and in a model of psoriasis.
Topics: Administration, Oral; Adult; Animals; Anti-Inflammatory Agents; Cell Proliferation; Cyclic Nucleotide Phosphodiesterases, Type 4; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Enterotoxins; Gene Expression Regulation; Humans; Inflammation Mediators; Keratinocytes; Killer Cells, Natural; Leukocytes, Mononuclear; Lipopolysaccharides; Mice; Mice, SCID; Middle Aged; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Psoriasis; RNA, Messenger; Severity of Illness Index; Skin; Skin Transplantation; Thalidomide; Time Factors; Transplantation, Heterologous; U937 Cells; Ultraviolet Rays; Zymosan | 2010 |
Intravital imaging of IL-1beta production in skin.
Topics: Animals; Arthritis; Cells, Cultured; Dermatitis, Contact; Disease Models, Animal; Interleukin-1beta; Lipopolysaccharides; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Oxazolone; Peritonitis; Skin; Zymosan | 2010 |
Zymosan priming protects rats against pulmonary oxygen toxicity: characterization of the model.
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Hyperoxia; Oxygen; Rats; Rats, Sprague-Dawley; Time Factors; Zymosan | 2010 |
Pharmacology of AM803, a novel selective five-lipoxygenase-activating protein (FLAP) inhibitor in rodent models of acute inflammation.
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Carrier Proteins; Chronic Disease; Cysteine; Disease Models, Animal; Female; Humans; Indoles; Inflammation; Leukotriene B4; Leukotrienes; Lung; Male; Membrane Proteins; Mice; Pentanoic Acids; Platelet Activating Factor; Propionates; Rats; Substrate Specificity; Zymosan | 2010 |
Circulating platelet-neutrophil complexes are important for subsequent neutrophil activation and migration.
Topics: Adult; Animals; Blood Platelets; Bronchoalveolar Lavage Fluid; Busulfan; CD18 Antigens; Cells, Cultured; Chemokine CCL17; Chemokine CCL22; Chemotaxis, Leukocyte; Disease Models, Animal; Female; Humans; Lipopolysaccharides; Male; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Middle Aged; Neutrophil Activation; Neutrophil Infiltration; Neutrophils; P-Selectin; Peritonitis; Platelet Adhesiveness; Pneumonia; Thrombocytopenia; Young Adult; Zymosan | 2010 |
Interleukin-18 as an in vivo mediator of monocyte recruitment in rodent models of rheumatoid arthritis.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Cell Movement; Chemotaxis; Chimera; Disease Models, Animal; Humans; Interleukin-18; Mice; Mice, Knockout; Mice, SCID; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Monocytes; p38 Mitogen-Activated Protein Kinases; Signal Transduction; Synovial Membrane; Zymosan | 2010 |
Panax notoginseng saponins attenuate atherogenesis accelerated by zymosan in rabbits.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Atherosclerosis; C-Reactive Protein; Chemokine CCL2; Cholesterol, Dietary; Diet, Atherogenic; Disease Models, Animal; Interleukin-6; Lipids; Male; Medicine, Chinese Traditional; NF-kappa B; Panax notoginseng; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; Saponins; Zymosan | 2010 |
Erythropoietin stimulates spleen BMP4-dependent stress erythropoiesis and partially corrects anemia in a mouse model of generalized inflammation.
Topics: Anemia; Animals; Apoptosis; Blotting, Western; Bone Marrow; Bone Morphogenetic Protein 4; Disease Models, Animal; Erythroid Precursor Cells; Erythropoiesis; Erythropoietin; Humans; Inflammation; Male; Mice; Mice, Inbred C57BL; Receptors, Erythropoietin; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Spleen; Zymosan | 2010 |
The 5-lipoxygenase inhibitor, zileuton, suppresses prostaglandin biosynthesis by inhibition of arachidonic acid release in macrophages.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Carrageenan; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Humans; Hydroxyurea; Interferon-gamma; Intramolecular Oxidoreductases; Lipopolysaccharides; Lipoxygenase Inhibitors; Macrophages; Mice; Mice, Inbred Strains; Pleurisy; Prostaglandin-E Synthases; Prostaglandins F; Rats; Rats, Wistar; Zymosan | 2010 |
Functional in vivo imaging of cysteine cathepsin activity in murine model of inflammation.
Topics: Animals; Anti-Inflammatory Agents; Cathepsins; Cysteine Proteases; Cysteine Proteinase Inhibitors; Dexamethasone; Disease Models, Animal; Fluorescent Dyes; Indoles; Inflammation; Leucine; Male; Mice; Phenazines; Zymosan | 2011 |
Experimental model of zymosan-induced arthritis in the rat temporomandibular joint: role of nitric oxide and neutrophils.
Topics: Animals; Arthritis, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Immunohistochemistry; Male; Neutrophil Infiltration; Neutrophils; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Synovial Fluid; Temporomandibular Joint; Temporomandibular Joint Disorders; Zymosan | 2011 |
Beneficial effect of a CXCR4 agonist in murine models of systemic inflammation.
Topics: Animals; Chemokine CXCL12; Disease Models, Animal; Endotoxemia; Interleukin-10; Interleukin-6; Lipopolysaccharides; Macrophages; Male; Mice; Multiple Organ Failure; Receptors, CXCR4; Sepsis; Systemic Inflammatory Response Syndrome; Tumor Necrosis Factor-alpha; Zymosan | 2012 |
Dectin-1 and NOD2 mediate cathepsin activation in zymosan-induced arthritis in mice.
Topics: Animals; Arthritis, Experimental; beta-Glucans; Cathepsins; Disease Models, Animal; Immunity, Innate; Joints; Lectins, C-Type; Membrane Proteins; Mice; Mice, Knockout; Nerve Tissue Proteins; Nod2 Signaling Adaptor Protein; Signal Transduction; Toll-Like Receptors; Zymosan | 2011 |
The lipid sulfatide is a novel myelin-associated inhibitor of CNS axon outgrowth.
Topics: Animals; Animals, Newborn; Antibodies; Axons; Cell Survival; Cells, Cultured; Central Nervous System Diseases; Disease Models, Animal; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Myelin Proteins; Nerve Regeneration; Neural Inhibition; Optic Nerve Injuries; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; rhoA GTP-Binding Protein; Sulfoglycosphingolipids; Sulfotransferases; Sulfurtransferases; Transfection; Zymosan | 2011 |
Effects of the anti-sepsis drug, (S)-1-(α-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (CKD-712), on mortality, inflammation, and organ injuries in rodent sepsis models.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Disease Models, Animal; Disseminated Intravascular Coagulation; Endotoxemia; Fever; Kidney; Lipopolysaccharides; Liver; Lung; Male; Mice; Mice, Inbred ICR; Rats; Rats, Sprague-Dawley; Sepsis; Survival Analysis; Tetrahydroisoquinolines; Zymosan | 2011 |
Hyperbaric oxygen therapy reduces the toll-like receptor signaling pathway in multiple organ failures.
Topics: Analysis of Variance; Animals; Blotting, Western; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hyperbaric Oxygenation; Immunohistochemistry; Interleukin-1beta; Male; Multiple Organ Failure; Random Allocation; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Toll-Like Receptors; Tumor Necrosis Factor-alpha; Zymosan | 2011 |
Total synthesis and bioactivity of 18(R)-hydroxyeicosapentaenoic acid.
Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Eicosapentaenoic Acid; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Neutrophil Infiltration; Peritonitis; Stereoisomerism; Zymosan | 2011 |
Panax notoginseng saponins inhibit Zymosan A induced atherosclerosis by suppressing integrin expression, FAK activation and NF-κB translocation.
Topics: Animals; Aorta; Atherosclerosis; Biological Transport; Disease Models, Animal; Foam Cells; Focal Adhesion Kinase 1; Integrins; Male; NF-kappa B; Panax notoginseng; Phosphorylation; Phytotherapy; Plant Extracts; Plaque, Atherosclerotic; Rats; Rats, Wistar; Saponins; Threonine; Zymosan | 2011 |
Repeated vulvovaginal fungal infections cause persistent pain in a mouse model of vulvodynia.
Topics: Animals; Candida albicans; Candidiasis, Vulvovaginal; Disease Models, Animal; Female; Hyperalgesia; Inflammation; Mice; Pain; Vagina; Vulva; Vulvodynia; Zymosan | 2011 |
Spinal cord Toll-like receptor 4 mediates inflammatory and neuropathic hypersensitivity in male but not female mice.
Topics: Analysis of Variance; Animals; Castration; Disease Models, Animal; Female; Gene Expression Regulation; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neuralgia; Pain Measurement; Polysaccharides; RNA, Messenger; Sex Characteristics; Spinal Cord; Testosterone Propionate; Time Factors; Toll-Like Receptor 4; Zymosan | 2011 |
Regulation of the inflammatory response: enhancing neutrophil infiltration under chronic inflammatory conditions.
Topics: Acute Disease; Animals; Chronic Disease; Colitis; Disease Models, Animal; Feedback, Physiological; Inflammation; Inflammation Mediators; Interleukin-17; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; Neutrophils; Peritonitis; Zymosan | 2012 |
[Preparation of rat model of systemic inflammatory response syndrome induced by zymosan].
Topics: Animals; Disease Models, Animal; Female; Interleukin-10; Interleukin-6; Male; Paraffin; Rats; Rats, Sprague-Dawley; Systemic Inflammatory Response Syndrome; Tumor Necrosis Factor-alpha; Viscera; Zymosan | 2011 |
[The protective effects of agmatine in zymosan induced acute lung injury in mice].
Topics: Acute Lung Injury; Agmatine; Animals; Disease Models, Animal; Inflammation; Interleukin-6; Lung; Male; Mice; Mice, Inbred C57BL; Tumor Necrosis Factor-alpha; Zymosan | 2011 |
Membrane complement regulators protect against fibrin exudation increases in a severe peritoneal inflammation model in rats.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Neutralizing; Antigens, Surface; CD59 Antigens; Complement Activation; Complement System Proteins; Disease Models, Animal; Fibrin; Homeostasis; Male; Peritoneal Dialysis; Peritoneum; Peritonitis; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Severity of Illness Index; Zymosan | 2012 |
Efficacy and toxicity of intravenous iron in a mouse model of critical care anemia*.
Topics: Anemia; Animals; Antimicrobial Cationic Peptides; Catalase; Diet; Disease Models, Animal; Ferric Compounds; Hematinics; Hemoglobins; Hepcidins; Inflammation; Injections, Intravenous; Iron; Liver; Luminescence; Maltose; Mice; Mice, Inbred C57BL; Phlebotomy; Random Allocation; Reactive Oxygen Species; RNA, Messenger; Sepsis; Spleen; Superoxide Dismutase; Trace Elements; Zymosan | 2012 |
[Analgesic effect of calpain inhibitor ALLN on the zymosan-induced paw inflammatory pain and its effect on the expression of cyclooxygenase-2 in the spinal dorsal horn].
Topics: Analgesics; Animals; Cyclooxygenase 2; Disease Models, Animal; Glycoproteins; Male; Pain; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Cord; Zymosan | 2012 |
Studies on the characteristic and activity of low-molecular fragments from zymosan.
Topics: Animals; beta-Glucans; Bile; Chromatography, Gel; Chronic Disease; Disease Models, Animal; Gastric Mucosa; Gastritis, Atrophic; Immunization; Inflammation; Molecular Weight; Rats; Rats, Wistar; Swine; Zymosan | 2012 |
Resident glial cell activation in response to perispinal inflammation leads to acute changes in nociceptive sensitivity: implications for the generation of neuropathic pain.
Topics: Animals; Astrocytes; Blood-Brain Barrier; Chronic Pain; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Female; Gliosis; Hyperesthesia; Leukocytes; Mice; Mice, Inbred BALB C; Microglia; Neuralgia; Neuritis; Nociceptors; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-fos; Spinal Cord; Zymosan | 2013 |
Modulation of zymosan-induced peritonitis by riboflavin co-injection, pre-injection or post-injection in male Swiss mice.
Topics: Animals; Apoptosis; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Inflammation; Inflammation Mediators; Injections, Intraperitoneal; Male; Matrix Metalloproteinase 9; Mice; Neutrophils; Nitric Oxide; Nociception; Peritonitis; Riboflavin; Time Factors; Zymosan | 2012 |
The role of PAF/PAFR signaling in zymosan-induced articular inflammatory hyperalgesia.
Topics: Animals; Dihydropyridines; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Imidazoles; Immune System Diseases; Inflammation; Joint Diseases; Leukocyte Disorders; Leukotriene B4; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandins; Receptors, G-Protein-Coupled; Time Factors; Zymosan | 2013 |
N-acetylcysteine administration is associated with reduced activation of NF-kB and preserves lung dendritic cells function in a zymosan-induced generalized inflammation model.
Topics: Acetylcysteine; Animals; Apoptosis; Cytokines; Dendritic Cells; Disease Models, Animal; Enzyme Activation; Histocompatibility Antigens Class II; Inflammation; Lung; Male; Mice; NF-kappa B; Receptors, CCR5; Receptors, CCR7; Respiratory Function Tests; RNA, Messenger; Zymosan | 2013 |
MicroRNA-mediated GABA Aα-1 receptor subunit down-regulation in adult spinal cord following neonatal cystitis-induced chronic visceral pain in rats.
Topics: 3' Untranslated Regions; Age Factors; Animals; Carcinoma, Embryonal; Cell Line, Tumor; Chronic Pain; Cystitis; Disease Models, Animal; Down-Regulation; Female; HEK293 Cells; Humans; Male; MicroRNAs; Pelvic Pain; Posterior Horn Cells; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Spinal Cord; Visceral Pain; Zymosan | 2013 |
Adjuvant effect of zymosan after pulmonary treatment in a mouse ovalbumin allergy model.
Topics: Adjuvants, Immunologic; Administration, Inhalation; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Dose-Response Relationship, Immunologic; Drug Hypersensitivity; Drug Therapy, Combination; Eosinophils; Immunoglobulin E; Interleukin-5; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Specific Pathogen-Free Organisms; Zymosan | 2013 |
Altered MARCH1 ubiquination-regulated dendritic cell immune functions during the early stage of zymosan-induced multiple organ dysfunction syndrome (MODS) in mice.
Topics: Animals; CD11c Antigen; Dendritic Cells; Disease Models, Animal; Disease Progression; Gene Expression; Histocompatibility Antigens Class II; Lymphocyte Activation; Male; Mice; Multiple Organ Failure; Proteasome Endopeptidase Complex; Proteolysis; RNA Interference; Spleen; T-Lymphocytes; Ubiquitin-Protein Ligases; Ubiquitination; Zymosan | 2013 |
The neuropathological and behavioral consequences of intraspinal microglial/macrophage activation.
Topics: Animals; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Avian Proteins; Axons; Basigin; Blood Proteins; Chemotaxis, Leukocyte; Denervation; Disease Models, Animal; Female; Gait Disorders, Neurologic; Gliosis; Immunohistochemistry; Macrophages; Membrane Glycoproteins; Microglia; Microinjections; Myelin Sheath; Myelitis; Nerve Degeneration; Nerve Fibers, Myelinated; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Zymosan | 2002 |
The anti-inflammatory effect of bee venom stimulation in a mouse air pouch model is mediated by adrenal medullary activity.
Topics: Adrenal Medulla; Adrenalectomy; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Bee Venoms; Catecholamines; Cell Movement; Disease Models, Animal; Exudates and Transudates; Hormone Antagonists; Inflammation; Injections, Subcutaneous; Leukocytes; Male; Mice; Mice, Inbred ICR; Mifepristone; Receptors, Steroid; Tumor Necrosis Factor-alpha; Zymosan | 2003 |
Opposite effects of rofecoxib on nuclear factor-kappaB and activating protein-1 activation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Disease Models, Animal; Inflammation; Lactones; Male; Mice; NF-kappa B; Rabbits; Rats; Rats, Sprague-Dawley; Sulfones; Transcription Factor AP-1; Zymosan | 2003 |
Participation of heme oxygenase-1 in a model of acute inflammation.
Topics: Animals; Cyclooxygenase 2; Disease Models, Animal; Female; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hemin; Inflammation; Isoenzymes; Macrophages, Peritoneal; Membrane Proteins; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Zymosan | 2003 |
A major role for non-major histocompatibility complex genes but not for microorganisms in a novel murine model of Graves' hyperthyroidism.
Topics: Adenoviridae; Animals; Antibodies; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Female; Graves Disease; Immunoglobulins; Injections, Intramuscular; Lipopolysaccharides; Major Histocompatibility Complex; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred DBA; Receptors, Thyrotropin; Thyroxine; Yeasts; Zymosan | 2003 |
LAAE-14, a new in vitro inhibitor of intracellular calcium mobilization, modulates acute and chronic inflammation.
Topics: Acute Disease; Animals; Arthritis, Experimental; Calcium; Carrageenan; Cell Movement; Chronic Disease; Dinoprostone; Disease Models, Animal; Edema; Humans; Inflammation; Leukotriene B4; Luminescent Measurements; Macrophages, Peritoneal; Mice; Neutrophils; Nitrites; Pancreatic Elastase; Rats; Tumor Necrosis Factor-alpha; Zymosan | 2003 |
[A small dose of intraperitoneal injection of zymosan induces systemic inflammatory response and multiple organ dysfunction following gut ischemia-reperfusion injury].
Topics: Animals; Disease Models, Animal; Male; Multiple Organ Failure; Rats; Rats, Wistar; Reperfusion Injury; Systemic Inflammatory Response Syndrome; Zymosan | 2003 |
[Replication of animal model and pathological study of delayed multiple organ dysfunction syndrome in mice].
Topics: Animals; Disease Models, Animal; Male; Mice; Mice, Inbred Strains; Multiple Organ Failure; Zymosan | 2003 |
Pyrrolidine dithiocarbamate attenuates the development of organ failure induced by zymosan in mice.
Topics: Animals; Antioxidants; Blotting, Western; Chemotaxis, Leukocyte; Disease Models, Animal; Drug Evaluation, Preclinical; Immunohistochemistry; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mice, Inbred Strains; Multiple Organ Failure; Neutrophils; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Poly(ADP-ribose) Polymerases; Pyrrolidines; Random Allocation; Thiocarbamates; Time Factors; Tyrosine; Zymosan | 2003 |
The pineal gland hormone melatonin improves survival in a rat model of sepsis/shock induced by zymosan A.
Topics: Animals; Disease Models, Animal; Male; Melatonin; Multiple Organ Failure; Rats; Rats, Sprague-Dawley; Sepsis; Shock; Zymosan | 2003 |
A new chloroquinolinyl chalcone derivative as inhibitor of inflammatory and immune response in mice and rats.
Topics: Abdominal Injuries; Administration, Oral; Animals; Arthritis, Experimental; Blood Platelets; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Dinitrofluorobenzene; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Hypersensitivity; Female; Formaldehyde; Group II Phospholipases A2; Group IV Phospholipases A2; Humans; Inflammation; Lipopolysaccharides; Lymphocyte Activation; Macrophages; Mice; Microsomes; Nitrites; Pain; Pain Measurement; Phospholipases A; Pyridazines; Rats; Rats, Inbred Lew; Thromboxane B2; Zymosan | 2003 |
Reactive nitrogen species scavenging, rather than nitric oxide inhibition, protects from articular cartilage damage in rat zymosan-induced arthritis.
Topics: Animals; Arthritis, Experimental; Cartilage, Articular; Disease Models, Animal; Dose-Response Relationship, Drug; Free Radical Scavengers; Glycosaminoglycans; Guanidines; Injections, Intra-Articular; Injections, Intraperitoneal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Peroxynitrous Acid; Rats; Rats, Wistar; Reactive Nitrogen Species; Synovial Fluid; Synovial Membrane; Synovitis; Tyrosine; Uric Acid; Zymosan | 2004 |
Protective effects of M40401, a selective superoxide dismutase mimetic, on zymosan-induced nonseptic shock.
Topics: Animals; Disease Models, Animal; Immunohistochemistry; Intestines; Lipid Peroxidation; Lung; Male; Multiple Organ Failure; Organometallic Compounds; Probability; Protective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Risk Assessment; Sensitivity and Specificity; Shock; Statistics, Nonparametric; Superoxide Dismutase; Zymosan | 2004 |
Specific Inhibition of IkappaB kinase reduces hyperalgesia in inflammatory and neuropathic pain models in rats.
Topics: Active Transport, Cell Nucleus; Analgesics; Animals; Anti-Inflammatory Agents; Cells, Cultured; Cyclooxygenase 2; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Formaldehyde; Humans; Hyperalgesia; I-kappa B Kinase; Inflammation; Injections, Intraperitoneal; Interleukin-1; Isoenzymes; Male; Membrane Proteins; Neuralgia; NF-kappa B; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Spinal Cord; Tumor Necrosis Factor-alpha; Up-Regulation; Zymosan | 2004 |
Zymosan induces nitric oxide production by peritoneal mesothelial cells.
Topics: Animals; Cell Culture Techniques; Disease Models, Animal; Epithelial Cells; Male; Nitric Oxide; Peritoneal Cavity; Peritonitis; Random Allocation; Rats; Rats, Wistar; Zymosan | 2004 |
Synaptic plasticity in the amygdala in a visceral pain model in rats.
Topics: Action Potentials; Amygdala; Animals; Colitis; Disease Models, Animal; Electric Stimulation; Emotions; Exploratory Behavior; Male; Neuronal Plasticity; Neurons; Pain; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Viscera; Visceral Afferents; Zymosan | 2004 |
Differential role of neutrophils and monocytes during subcutaneous plasma extravasation.
Topics: Animals; Apoptosis; Capillary Permeability; Cell Movement; Chemotactic Factors; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Guinea Pigs; HL-60 Cells; Humans; Macrophage Colony-Stimulating Factor; Male; Monocytes; Neutrophils; Plasma; Ribosomal Proteins; Subcutaneous Tissue; Zymosan | 2004 |
Methylguanidine reduces the development of non septic shock induced by zymosan in mice.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Exudates and Transudates; Immunohistochemistry; Intestinal Mucosa; Intestines; Kidney; Lipid Peroxidation; Lung; Male; Methylguanidine; Mice; Neutrophils; Pancreas; Peritonitis; Peroxidase; Peroxynitrous Acid; Poly(ADP-ribose) Polymerases; Shock; Tyrosine; Zymosan | 2004 |
Peri-sciatic proinflammatory cytokines, reactive oxygen species, and complement induce mirror-image neuropathic pain in rats.
Topics: Animals; Antibodies; Behavior, Animal; Carrier Proteins; Catalase; Complement System Proteins; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Functional Laterality; Hyperalgesia; Interleukin 1 Receptor Antagonist Protein; Interleukin-6; Male; Neuralgia; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Complement; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Sciatic Nerve; Sciatic Neuropathy; Sialoglycoproteins; Superoxide Dismutase; Tumor Necrosis Factor Decoy Receptors; Zymosan | 2004 |
Increased activity of the intestinal mucosal mast cells in rats with multiple organ failure.
Topics: Animals; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Fluorometry; Histamine; Immunohistochemistry; Intestinal Mucosa; Multiple Organ Failure; Rats; Tumor Necrosis Factor-alpha; Zymosan | 2004 |
Modeling MODS: what can be learned from animal models of the multiple-organ dysfunction syndrome?
Topics: Animals; Disease Models, Animal; Immunologic Factors; Mice; Multiple Organ Failure; Pentoxifylline; PPAR gamma; Prostaglandin D2; Vasodilator Agents; Zymosan | 2005 |
Altered chemokine response in an animal model of multiple organ dysfunction syndrome induced by zymosan.
Topics: Animals; Ascitic Fluid; Bronchoalveolar Lavage Fluid; Chemokine CCL2; Chemokines; Disease Models, Animal; Injections, Intraperitoneal; Male; Multiple Organ Failure; Peritonitis; Random Allocation; Rats; Rats, Sprague-Dawley; Zymosan | 2005 |
Hypertonic saline modulates innate immunity in a model of systemic inflammation.
Topics: Animals; Blotting, Western; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Down-Regulation; Enzyme Activation; Inflammation; Lipopolysaccharides; Macrophages; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Rats; Rats, Wistar; Saline Solution, Hypertonic; Signal Transduction; Tumor Necrosis Factor-alpha; Zymosan | 2005 |
Comparative proteomic analysis of the rat spinal cord in inflammatory and neuropathic pain models.
Topics: Animals; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Hindlimb; Inflammation; Ligation; Male; Neuralgia; Proteomics; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spinal Cord; Zymosan | 2005 |
Annexin 1-deficient neutrophils exhibit enhanced transmigration in vivo and increased responsiveness in vitro.
Topics: Animals; Annexin A1; CD11b Antigen; Chemotaxis; Disease Models, Animal; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Muscle, Skeletal; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Time Factors; Zymosan | 2005 |
The melanocortin peptide HP228 displays protective effects in acute models of inflammation and organ damage.
Topics: Acute Disease; alpha-MSH; Animals; Anti-Inflammatory Agents; Blood Pressure; Carrageenan; Chemokine CXCL1; Chemokines; Chemokines, CXC; Cyclic AMP; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Inflammation; Interleukin-1; Macrophages, Peritoneal; Male; Mice; Myocardial Reperfusion Injury; Oligopeptides; Peritonitis; Time Factors; Tumor Necrosis Factor-alpha; Uric Acid; Zymosan | 2006 |
Imaging of hyperalgesia in rats by functional MRI.
Topics: Afferent Pathways; Animals; Brain; Brain Mapping; Cerebrovascular Circulation; Disease Models, Animal; Hyperalgesia; Inflammation Mediators; Magnetic Resonance Imaging; Male; Neural Pathways; Nociceptors; Pain Measurement; Pain Threshold; Predictive Value of Tests; Rats; Rats, Wistar; Zymosan | 2007 |
Gelatinase B/matrix metalloproteinase-9 contributes to cellular infiltration in a murine model of zymosan peritonitis.
Topics: Animals; Cell Movement; Chemokines; Disease Models, Animal; Enzyme Precursors; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Peritonitis; Recombinant Proteins; Tissue Inhibitor of Metalloproteinase-1; Zymosan | 2006 |
Role of spinal microglia in rat models of peripheral nerve injury and inflammation.
Topics: Animals; Citrates; Disease Models, Animal; Functional Laterality; Glial Fibrillary Acidic Protein; Hyperalgesia; Male; Microglia; Neuritis; Pain Threshold; Posterior Horn Cells; Rats; Rats, Wistar; Sciatic Nerve; Spinal Cord; Zymosan | 2007 |
Substantial role of locus coeruleus-noradrenergic activation and capsaicin-insensitive primary afferent fibers in bee venom's anti-inflammatory effect.
Topics: Adrenergic Agents; Animals; Anti-Inflammatory Agents; Bee Venoms; Capsaicin; Disease Models, Animal; Diterpenes; Drug Interactions; Functional Laterality; Gene Expression; Inflammation; Leukocytes; Locus Coeruleus; Mice; Mice, Inbred ICR; Norepinephrine; Oncogene Proteins v-fos; Oxidopamine; Sciatic Neuropathy; Zymosan | 2006 |
Anti-inflammatory and anti-nociceptive activity of risedronate in experimental pain models in rats and mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Diphosphonates; Disease Models, Animal; Dose-Response Relationship, Drug; Etidronic Acid; Inflammation; Leukotriene B4; Male; Mice; Pain; Pain Measurement; Rats; Rats, Wistar; Risedronic Acid; Tumor Necrosis Factor-alpha; Zymosan | 2006 |
A comparison of elderly and adult multiple organ dysfunction syndrome in the rat model.
Topics: Aging; Animals; Apoptosis; Body Weight; Bronchoalveolar Lavage Fluid; Calcium; Carbon Dioxide; Cytokines; Disease Models, Animal; Lung; Macrophages, Alveolar; Male; Multiple Organ Failure; Myocardium; Organ Size; Oxygen; Partial Pressure; Rats; Rats, Sprague-Dawley; Zymosan | 2006 |
Intrathecal clonidine suppresses zymosan-induced peripheral leukocyte migration in a mouse air pouch model via activation of spinal muscarinic type 2 receptors and sympathoadrenal medullary activity.
Topics: Adrenalectomy; Analysis of Variance; Animals; Cell Count; Cell Movement; Choline O-Acetyltransferase; Clonidine; Disease Models, Animal; Drug Interactions; Ganglia, Sympathetic; Immunohistochemistry; Inflammation; Leukocytes; Male; Mice; Mice, Inbred ICR; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Oncogene Proteins v-fos; Receptor, Muscarinic M2; Spinal Cord; Sympathectomy, Chemical; Sympatholytics; Zymosan | 2006 |
Investigations on the anti-inflammatory and anti-allergic activities of the leaves of Uncaria guianensis (Aublet) J. F. Gmelin.
Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Cells, Cultured; Chemokine CXCL1; Chemokines, CXC; Chemotaxis, Leukocyte; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Intercellular Signaling Peptides and Proteins; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Plant Extracts; Plant Leaves; Pleurisy; Tumor Necrosis Factor-alpha; Uncaria; Zymosan | 2006 |
Pulmonary exposure to 1 --> 3-beta-glucan alters adaptive immune responses in rats.
Topics: Air Pollutants; Animals; Bronchoalveolar Lavage Fluid; Cell Proliferation; Cytokines; Disease Models, Animal; Immunity, Cellular; Immunocompetence; Immunophenotyping; Inflammation; Inhalation Exposure; Intubation, Intratracheal; Lung; Lymph Nodes; Lymphocytes; Macrophages, Alveolar; Male; Neutrophils; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Zymosan | 2006 |
UCP3 in muscle wasting, a role in modulating lipotoxicity?
Topics: Aldehydes; Animals; Cachexia; Disease Models, Animal; Humans; Ion Channels; Lipid Peroxidation; Male; Mitochondrial Proteins; Muscle, Skeletal; Muscular Atrophy; Oxidation-Reduction; Oxidative Stress; Protein Biosynthesis; Rats; Rats, Wistar; Sepsis; Uncoupling Protein 3; Wasting Syndrome; Zymosan | 2006 |
Cytokine production profile of splenocytes derived from zymosan A-treated SKG mice developing arthritis.
Topics: Animals; Arthritis; Arthritis, Experimental; Cytokines; Disease Models, Animal; Interleukin-2; Interleukin-4; Interleukin-6; Mice; Mice, Inbred BALB C; Species Specificity; Spleen; T-Lymphocytes; Th2 Cells; Zymosan | 2006 |
Resolvin E2: identification and anti-inflammatory actions: pivotal role of human 5-lipoxygenase in resolvin E series biosynthesis.
Topics: Animals; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Disease Models, Animal; Eicosapentaenoic Acid; Humans; Mice; Neutrophils; Peritonitis; Zymosan | 2006 |
Sensory neuron and substance P involvement in symptoms of a zymosan-induced rat model of acute bowel inflammation.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Colitis; Colon; Disease Models, Animal; Enteric Nervous System; Ethanol; Inflammation Mediators; Male; Neurogenic Inflammation; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Oligonucleotides, Antisense; Pain; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; RNA, Messenger; Substance P; Sympathetic Nervous System; Zymosan | 2007 |
Low-frequency electroacupuncture suppresses zymosan-induced peripheral inflammation via activation of sympathetic post-ganglionic neurons.
Topics: Acetylcholinesterase; Adrenergic beta-Antagonists; Animals; Catecholamines; Chemotaxis, Leukocyte; Disease Models, Animal; Electroacupuncture; Inflammation; Inflammation Mediators; Male; Mice; Mice, Inbred ICR; Neurons; Presynaptic Terminals; Skin; Spinal Cord; Sympathectomy, Chemical; Sympathetic Fibers, Postganglionic; Zymosan | 2007 |
Beneficial effects of erythropoietin in preclinical models of shock and organ failure.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Endotoxemia; Erythropoietin; Mice; Multiple Organ Failure; Shock; Shock, Hemorrhagic; Shock, Septic; Spinal Cord Injuries; Treatment Outcome; Zymosan | 2007 |
Short-term sensitization of colon mechanoreceptors is associated with long-term hypersensitivity to colon distention in the mouse.
Topics: Acid Sensing Ion Channels; Animals; Colon; Disease Models, Animal; Electromyography; Gastrointestinal Motility; Irritable Bowel Syndrome; Male; Mechanoreceptors; Mice; Mice, Inbred C57BL; Mice, Knockout; Nociceptors; Sodium Channels; TRPV Cation Channels; Zymosan | 2007 |
The effect of zymosan and the protective effect of various antioxidants on fracture healing in rats.
Topics: Animals; Antioxidants; Ascorbic Acid; Dimethyl Sulfoxide; Disease Models, Animal; Fracture Healing; Free Radical Scavengers; Free Radicals; Ginkgo biloba; Male; Plant Extracts; Radius Fractures; Random Allocation; Rats; Rats, Wistar; Research Design; Statistics, Nonparametric; Time Factors; Ulna Fractures; Zymosan | 2007 |
Low-level laser therapy for zymosan-induced arthritis in rats: Importance of illumination time.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Dexamethasone; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Radiation; Female; Low-Level Light Therapy; Polysaccharides; Rats; Rats, Inbred Lew; Time Factors; Zymosan | 2007 |
Inflammation-induced enhancement of the visceromotor reflex to urinary bladder distention: modulation by endogenous opioids and the effects of early-in-life experience with bladder inflammation.
Topics: Age Factors; Analgesics, Opioid; Analysis of Variance; Animals; Animals, Newborn; Dilatation, Pathologic; Disease Models, Animal; Electromyography; Female; Inflammation; Muscle Contraction; Naloxone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Sprague-Dawley; Reflex; Urinary Bladder Diseases; Viscera; Zymosan | 2007 |
[Implications of lung interstitial dendritic cells of mice in multiple organ dysfunction syndrome].
Topics: Animals; Antigens, CD; B7-1 Antigen; B7-2 Antigen; CD11c Antigen; CD4-CD8 Ratio; Cell Proliferation; Chemokine CCL21; Dendritic Cells; Disease Models, Animal; Lectins, C-Type; Male; Mice; Mice, Inbred C57BL; Minor Histocompatibility Antigens; Multiple Organ Failure; Random Allocation; Receptors, CCR7; Receptors, Cell Surface; Zymosan | 2007 |
Acute peritonitis in a C57BL/6 mouse model of peritoneal dialysis.
Topics: Acute Disease; Animals; Dinoprostone; Disease Models, Animal; Escherichia coli; In Vitro Techniques; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Peritoneal Dialysis; Peritonitis; Vascular Endothelial Growth Factor A; Zymosan | 2007 |
Involvement of LTB4 in zymosan-induced joint nociception in mice: participation of neutrophils and PGE2.
Topics: Animals; Arachidonate 5-Lipoxygenase; Benzopyrans; Carboxylic Acids; Cell Movement; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Indoles; Leukotriene B4; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Temporomandibular Joint; Temporomandibular Joint Disorders; Time Factors; Zymosan | 2008 |
Anti-inflammatory effects of orally ingested lactoferrin and glycine in different zymosan-induced inflammation models: evidence for synergistic activity.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Drug Synergism; Glycine; Inflammation; Lactoferrin; Male; Mice; Mice, Inbred BALB C; Proteoglycans; Tumor Necrosis Factor-alpha; Zymosan | 2007 |
Oligodendrocyte generation is differentially influenced by toll-like receptor (TLR) 2 and TLR4-mediated intraspinal macrophage activation.
Topics: Animals; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cell Line; Cell Proliferation; Cell Transplantation; Ciliary Neurotrophic Factor; Disease Models, Animal; Female; Gene Expression Regulation; Lipopolysaccharides; Macrophage Activation; Myelitis; Oligodendroglia; Rats; Rats, Sprague-Dawley; Stem Cells; Time Factors; Toll-Like Receptor 2; Toll-Like Receptor 4; Zymosan | 2007 |
Monocyte chemoattractant protein-1 and nitric oxide promote adipogenesis in a model that mimics obesity.
Topics: Adipogenesis; Adipose Tissue; Animals; Cell Movement; Chemokine CCL2; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Macrophages; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type II; Obesity; Tissue Engineering; Zymosan | 2007 |
Trauma-hemorrhage inhibits splenic dendritic cell proinflammatory cytokine production via a mitogen-activated protein kinase process.
Topics: Abdomen; Abdominal Injuries; Animals; Cells, Cultured; Cytokines; Dendritic Cells; Disease Models, Animal; Down-Regulation; Enzyme Activation; Hemorrhage; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Lymphocyte Antigen 96; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C3H; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Spleen; Time Factors; Toll-Like Receptor 2; Toll-Like Receptor 4; Zymosan | 2008 |
Gelatinase B/MMP-9 as an inflammatory marker enzyme in mouse zymosan peritonitis: comparison of phase-specific and cell-specific production by mast cells, macrophages and neutrophils.
Topics: Animals; Antibodies, Monoclonal; Biomarkers; Blotting, Western; Disease Models, Animal; Macrophages; Male; Mast Cells; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Neutrophils; Peritonitis; Zymosan | 2008 |
Properdin deficiency in murine models of nonseptic shock.
Topics: alpha 1-Antitrypsin; Animals; Complement C5a; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Interleukin-10; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nitric Oxide; Properdin; Shock; Tumor Necrosis Factor-alpha; Zymosan | 2008 |
Characterization of endotoxin-induced C5-derived chemotactic activity in aqueous humor.
Topics: Animals; Aqueous Humor; Cell Movement; Chemotactic Factors; Chemotaxis; Complement C3; Complement C5; Complement C5a; Disease Models, Animal; Endotoxins; Female; Glucuronidase; Injections, Intravenous; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rabbits; Salmonella typhimurium; Uveitis, Anterior; Zymosan | 1984 |
Pathogenesis of atoxinogenic strains of gram--negative bacteria--a hypothesis.
Topics: Animals; Bacteria; Bacterial Infections; Disease Models, Animal; Endotoxins; Gonorrhea; Humans; Mice; Mice, Inbred Strains; Neisseria gonorrhoeae; Salmonella Infections; Salmonella typhimurium; Species Specificity; Zymosan | 1982 |
Biochemical and morphologic changes in rabbit lung following endotracheal instillation of zymosan particles.
Topics: Animals; Disease Models, Animal; Enzyme Activation; Inflammation; Leukocyte Count; Lung Diseases; Macrophage Activation; Phagocytosis; Pulmonary Alveoli; Rabbits; Zymosan | 1983 |
Production of acute pulmonary injury by leukocytes and activated complement.
Topics: Agranulocytosis; Animals; Complement Activation; Complement Pathway, Alternative; Disease Models, Animal; Female; Hypoxia; Leukocyte Count; Leukopenia; Lung; Microscopy, Electron; Neutrophils; Oxygen; Rabbits; Respiration; Respiratory Distress Syndrome; Thrombosis; Zymosan | 1980 |
Trimetazidine inhibits neutrophil accumulation after myocardial ischaemia and reperfusion in rabbits.
Topics: Animals; Blood Pressure; Capillary Permeability; Disease Models, Animal; Heart Rate; Interleukin-8; Leukotriene B4; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Neutrophils; Rabbits; Trimetazidine; Zymosan | 1993 |
Antiatherosclerotic effects of oral naftidrofuryl in cholesterol-fed rabbits involve inhibition of neutrophil function.
Topics: Acetylcholine; Administration, Oral; Animals; Aorta, Abdominal; Aorta, Thoracic; Arteriosclerosis; Cholesterol; Cholesterol, Dietary; Disease Models, Animal; Endothelium, Vascular; Fibrinogen; Luminescent Measurements; Luminol; Male; Molsidomine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nafronyl; Neutrophils; Nitric Oxide; Rabbits; Random Allocation; Substance P; Vasodilator Agents; Zymosan | 1995 |
Post-capillary venules in the "milky spots" of the greater omentum are the major site of plasma protein and leukocyte extravasation in rodent models of peritonitis.
Topics: Animals; Arthritis; Blood Flow Velocity; Blood Proteins; Disease Models, Animal; Indoles; Leukocytes; Male; Mice; Microscopy, Electron; Omentum; Organometallic Compounds; Peritoneum; Peritonitis; Pleurisy; Rats; Staining and Labeling; Venules; Zymosan | 1995 |
Volatile anesthetic modulation of lung injury and outcome in a murine model of multiple organ dysfunction syndrome.
Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Mice; Multiple Organ Failure; Peroxidase; Respiratory Distress Syndrome; Treatment Outcome; Zymosan | 1995 |
[The effect of x-rays on experimental arthritis in the rat].
Topics: Acute Disease; Animals; Disease Models, Animal; Male; Mycobacterium tuberculosis; Osteoarthritis; Patellar Ligament; Radiotherapy Dosage; Rats; Rats, Wistar; Tuberculosis, Osteoarticular; Zymosan | 1995 |
Measurement and drug induced modulation of interleukin-1 level during zymosan peritonitis in mice.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Biological Assay; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Indomethacin; Interleukin-1; Male; Mice; Peritonitis; Thiophenes; Zymosan | 1995 |
Deficiency of complement factor C5 reduces early mortality but does not prevent organ damage in an animal model of multiple organ dysfunction syndrome.
Topics: Aging; Animals; Complement Activation; Complement C5; Disease Models, Animal; Injections, Intraperitoneal; Male; Mice; Multiple Organ Failure; Organ Size; Zymosan | 1995 |
Effect of a total extract from Fraxinus ornus stem bark and esculin on zymosan- and carrageenan-induced paw oedema in mice.
Topics: Animals; Bulgaria; Carrageenan; Complement Activation; Complement Hemolytic Activity Assay; Complement Inactivator Proteins; Disease Models, Animal; Edema; Esculin; Ethanol; Hindlimb; Injections, Intraperitoneal; Mice; Plant Extracts; Trees; Zymosan | 1995 |
Prolonged changes in protein and amino acid metabolism after zymosan treatment in rats.
Topics: Acute Disease; Amino Acids; Animals; Body Weight; Critical Illness; Disease Models, Animal; Liver; Male; Muscle Proteins; Muscle, Skeletal; Organ Size; Rats; Rats, Inbred Lew; Zymosan | 1994 |
The effect of hyperthermia (42.5 degrees C) on zymosan-induced synovitis of the knee.
Topics: Animals; Disease Models, Animal; Hyperthermia, Induced; Knee Joint; Microwaves; Pilot Projects; Rabbits; Synovitis; Zymosan | 1994 |
[Evaluation of an experimental model of multiple organ dysfunction].
Topics: Animals; Disease Models, Animal; Lung; Male; Multiple Organ Failure; Organ Size; Rats; Rats, Wistar; Survival Rate; Tomography, X-Ray Computed; Zymosan | 1994 |
Changes in myocardial blood flow rates during hyperdynamic sepsis with induced changes in arterial perfusing pressures and metabolic need.
Topics: Alprostadil; Animals; Blood Flow Velocity; Disease Models, Animal; Hemodynamics; Infusions, Intravenous; Isotope Labeling; Male; Microspheres; Myocardial Ischemia; Oxygen Consumption; Plasma; Sepsis; Sheep; Thermodilution; Ventricular Function; Zymosan | 1993 |
Relationship between liver oxidant stress and antioxidant activity after zymosan peritonitis in the rat.
Topics: Acidosis, Lactic; Animals; Antioxidants; Blood Gas Analysis; Disease Models, Animal; Glutathione; Inflammation; Liver; Male; Malondialdehyde; Oxidants; Oxygen Consumption; Peritonitis; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors; Xanthine Dehydrogenase; Xanthine Oxidase; Zymosan | 1993 |
Effect of rolipram in a murine model of acute inflammation: comparison with the corticoid dexamethasone.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation; Interleukin-1; Leukocyte Elastase; Leukocytes; Male; Mice; Pancreatic Elastase; Phosphodiesterase Inhibitors; Pyrrolidinones; Rolipram; Time Factors; Tumor Necrosis Factor-alpha; Zymosan | 1995 |
The effect of leukotriene synthesis inhibitors in models of acute and chronic inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Chronic Disease; Disease Models, Animal; Drug Combinations; Exudates and Transudates; Female; Hydroxyurea; Inflammation; Leukotriene B4; Lipoxygenase; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Naproxen; Prostaglandin-Endoperoxide Synthases; Quinolines; Time Factors; Zymosan | 1996 |
Inflammatory cytokines in an experimental model for the multiple organ dysfunction syndrome.
Topics: Animals; Cytokines; Disease Models, Animal; In Vitro Techniques; Inflammation; Interleukin-1; Interleukin-6; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Multiple Organ Failure; Tumor Necrosis Factor-alpha; Zymosan | 1996 |
Aprotinin prevents the development of the trauma-induced multiple organ failure in a chronic sheep model.
Topics: Animals; Aprotinin; Capillary Permeability; Disease Models, Animal; Endotoxins; Escherichia coli; Female; Femoral Artery; Heart; Hemodynamics; Hemorrhage; Hemostatics; Kidney; L-Lactate Dehydrogenase; Leukocyte Count; Liver; Lung; Multiple Organ Failure; Neutrophils; Serine Proteinase Inhibitors; Sheep; Wounds and Injuries; Zymosan | 1996 |
Increasing cytotoxic activity and production of reactive oxygen and nitrogen intermediates by peritoneal macrophages during the development of multiple organ dysfunction syndrome in mice.
Topics: Animals; Antibody-Dependent Cell Cytotoxicity; Cytotoxicity, Immunologic; Disease Models, Animal; Inflammation; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Multiple Organ Failure; Nitric Oxide; Phagocytosis; Superoxides; Syndrome; Zymosan | 1996 |
Treatment of experimental inflammatory synovitis with continuous magnetic field.
Topics: Animals; Arthritis; Disease Models, Animal; Female; Knee; Magnetics; Rats; Rats, Wistar; Severity of Illness Index; Synovitis; Zymosan | 1996 |
Quantification of mRNA levels in joint capsule and articular cartilage of the murine knee joint by RT-PCR: kinetics of stromelysin and IL-1 mRNA levels during arthritis.
Topics: Animals; Arthritis; Biopsy; Cartilage, Articular; Disease Models, Animal; DNA Primers; Gene Expression; Interleukin-1; Joint Capsule; Knee Joint; Matrix Metalloproteinase 3; Mice; Mice, Inbred C57BL; Polymerase Chain Reaction; RNA, Messenger; Zymosan | 1997 |
Organ damage is preceded by changes in protein extravasation in an experimental model of multiple organ dysfunction syndrome.
Topics: Animals; Body Fluid Compartments; Body Temperature; Body Weight; Capillary Permeability; Disease Models, Animal; Extracellular Space; Male; Mice; Mice, Inbred C57BL; Multiple Organ Failure; Proteins; Zymosan | 1997 |
Inhibition of warm ischemic injury to rat liver, pancreas, and heart grafts by controlling the nutritional status of both donor and recipient.
Topics: Animals; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Fasting; Fatty Acids, Essential; Heart Transplantation; Liver Transplantation; Nutritional Status; Pancreas Transplantation; Rats; Reperfusion Injury; Transplantation, Heterotopic; Tumor Necrosis Factor-alpha; Zymosan | 1997 |
Multiple organ failure following zymosan-induced peritonitis is mediated by nitric oxide.
Topics: Acute Disease; Animals; Disease Models, Animal; Enzyme Induction; Injections, Intraperitoneal; Male; Multiple Organ Failure; Nitric Oxide; Nitric Oxide Synthase; Peritonitis; Random Allocation; Rats; Rats, Sprague-Dawley; Zymosan | 1997 |
Gradual development of organ damage in the murine zymosan-induced multiple organ dysfunction syndrome.
Topics: Animals; Disease Models, Animal; Disease Progression; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Multiple Organ Failure; Organ Size; Survival Rate; Time Factors; Zymosan | 1997 |
Endogenous monocyte chemoattractant protein-1 recruits monocytes in the zymosan peritonitis model.
Topics: Acute Disease; Animals; Chemokine CCL2; Chemotaxis, Leukocyte; Dexamethasone; Disease Models, Animal; Glucocorticoids; Macrophage-1 Antigen; Male; Mice; Monocytes; Peritonitis; Vinblastine; Zymosan | 1998 |
Platelet-activating factor plays a pivotal role in the induction of experimental lung injury.
Topics: Animals; Capillary Permeability; Dihydropyridines; Disease Models, Animal; Elapid Venoms; Extravascular Lung Water; Female; Humans; Imidazoles; Lipopolysaccharides; Lung; Mice; Mice, Inbred BALB C; Neutrophils; Peroxidase; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Respiratory Distress Syndrome; Serum Albumin; Skin; Zymosan | 1998 |
Suppression of acute lung injury in mice by an inhibitor of phosphodiesterase type 4.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Capillary Permeability; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; Female; Humans; Infant, Newborn; Lipopolysaccharides; Lung; Mice; Mice, Inbred BALB C; Neutrophils; Phosphodiesterase Inhibitors; Pulmonary Circulation; Pyrrolidinones; Respiratory Distress Syndrome; Rolipram; Time Factors; Tumor Necrosis Factor-alpha; Zymosan | 1998 |
Stem cell factor-deficient mice have a dysregulation of cytokine production during local inflammation.
Topics: Animals; Ascitic Fluid; Body Weight; Cytokines; Disease Models, Animal; Female; Hypoglycemia; Inflammation; Irritants; Mice; Mice, Mutant Strains; Peritoneal Cavity; Peritonitis; Stem Cell Factor; Turpentine; Weight Loss; Zymosan | 1998 |
Peroxynitrate-mediated DNA strand breakage activates poly(ADP-ribose) synthetase and causes cellular energy depletion in a nonseptic shock model induced by zymosan in the rat.
Topics: Animals; Benzamides; Disease Models, Animal; DNA Damage; Energy Metabolism; Enzyme Activation; Macrophages, Peritoneal; Male; Mitochondria; NAD; NG-Nitroarginine Methyl Ester; Niacinamide; Nitrates; Nitric Oxide Synthase; Oxidants; Oxygen Consumption; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Shock; Zymosan | 1998 |
Effect of obstructive jaundice on neutrophil chemotactic activity: an in vivo assessment in zymosan-induced peritonitis model in rats.
Topics: Animals; Ascitic Fluid; Chemotaxis, Leukocyte; Cholestasis; Disease Models, Animal; Injections, Intraperitoneal; Male; Neutrophils; Peritoneal Lavage; Peritonitis; Peroxidase; Rats; Rats, Wistar; Zymosan | 1998 |
Spontaneous skin ulceration and defective T cell function in CD18 null mice.
Topics: Animals; CD18 Antigens; Cell Adhesion; Cell Division; Disease Models, Animal; Enterotoxins; Histocytochemistry; Humans; Leukocyte-Adhesion Deficiency Syndrome; Mice; Mice, Knockout; Neutrophils; Phenotype; Receptors, Antigen, T-Cell; Respiratory Burst; Skin Ulcer; Streptococcus pneumoniae; T-Lymphocytes; Zymosan | 1998 |
Chlorpromazine down-regulates tumor necrosis factor-alpha and attenuates experimental multiple organ dysfunction syndrome in mice.
Topics: Animals; Chlorpromazine; Disease Models, Animal; Down-Regulation; Drug Administration Schedule; Immunologic Factors; Male; Mice; Mice, Inbred C57BL; Multiple Organ Failure; Prospective Studies; Random Allocation; Tumor Necrosis Factor-alpha; Zymosan | 1998 |
Multiple organ failure (MOF) after severe trauma--a sheep model.
Topics: Albumins; Animals; Bronchoalveolar Lavage Fluid; Capillary Permeability; Disease Models, Animal; Disease Progression; Endotoxins; Female; Femur; Fracture Fixation, Intramedullary; Heart Function Tests; Least-Squares Analysis; Leukocyte Count; Liver; Lung; Multiple Organ Failure; Multiple Trauma; Sheep; Shock; Zymosan | 1998 |
Anti-hyperalgesic properties of the extract and of the main sesquiterpene polygodial isolated from the barks of Drymis winteri (Winteraceae).
Topics: Abdominal Pain; Acetic Acid; Animals; Bradykinin; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Formaldehyde; Hyperalgesia; Male; Mice; Motor Activity; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Sesquiterpenes; Substance P; Zymosan | 1998 |
Interleukin-10 reduces morbidity and mortality in murine multiple organ dysfunction syndrome (MODS).
Topics: Animals; Disease Models, Animal; Disease Progression; Interleukin-10; Male; Mice; Mice, Inbred ICR; Multiple Organ Failure; Specific Pathogen-Free Organisms; Survival Analysis; Zymosan | 1998 |
Effects of hyperbaric oxygen exposure on a zymosan-induced shock model.
Topics: Animals; Disease Models, Animal; Hyperbaric Oxygenation; Male; Nitric Oxide; Random Allocation; Rats; Rats, Sprague-Dawley; Shock; Survival Analysis; Time Factors; Tumor Necrosis Factor-alpha; Zymosan | 1998 |
Protective effect of N-acetylcysteine on cellular energy depletion in a non-septic shock model induced by zymosan in the rat.
Topics: Acetylcysteine; Animals; Cell Membrane Permeability; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Energy Metabolism; Free Radical Scavengers; Macrophages, Peritoneal; Male; NAD; Nitrates; Nitric Oxide; Rats; Rats, Sprague-Dawley; Sepsis; Shock; Tyrosine; Zymosan | 1999 |
Regulation of macrophage inflammatory protein-1 alpha expression and function by endogenous interleukin-10 in a model of acute inflammation.
Topics: Acute Disease; Animals; Cell Movement; Chemokine CCL3; Chemokine CCL4; Disease Models, Animal; Injections, Intraperitoneal; Interleukin-10; Leukocyte Count; Macrophage Inflammatory Proteins; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Neutrophils; Peritonitis; Zymosan | 1999 |
Kinetics of aggrecanase- and metalloproteinase-induced neoepitopes in various stages of cartilage destruction in murine arthritis.
Topics: Animals; Arthritis, Experimental; Cartilage, Articular; Collagen; Disease Models, Animal; Endopeptidases; Epitopes; Immunoenzyme Techniques; Knee Joint; Metalloendopeptidases; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Oligopeptides; Peptide Fragments; Zymosan | 1999 |
Protective effect of N-acetylcysteine on multiple organ failure induced by zymosan in the rat.
Topics: Acetylcysteine; Animals; Body Weight; Disease Models, Animal; Drug Evaluation, Preclinical; Free Radical Scavengers; Leukocyte Count; Male; Multiple Organ Failure; Nitrates; Nitric Oxide; Peritonitis; Random Allocation; Rats; Rats, Sprague-Dawley; Shock, Septic; Survival Analysis; Time Factors; Zymosan | 1999 |
Protective effect of poly(ADP-ribose) synthetase inhibition on multiple organ failure after zymosan-induced peritonitis in the rat.
Topics: Animals; Benzamides; Body Weight; Disease Models, Animal; Drug Evaluation, Preclinical; Male; Multiple Organ Failure; Niacinamide; Nitrates; Peritonitis; Poly(ADP-ribose) Polymerase Inhibitors; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors; Zymosan | 1999 |
Elucidation of the early events contributing to zymosan-induced multiple organ dysfunction syndrome using MIP-1alpha, C3 knockout, and C5-deficient mice.
Topics: Animals; Chemokine CCL3; Chemokine CCL4; Complement Activation; Complement C3; Complement C5; Disease Models, Animal; Exudates and Transudates; Injections, Intraperitoneal; Kidney; Leukocyte Count; Lung; Macrophage Inflammatory Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Mice, Mutant Strains; Multiple Organ Failure; Myocardium; Neutrophil Infiltration; Peritonitis; Spleen; Transaminases; Zymosan | 1999 |
Role of melatonin in reduction of lipid peroxidation and peroxynitrite formation in non-septic shock induced by zymosan.
Topics: Animals; Antioxidants; Disease Models, Animal; Exudates and Transudates; Immunohistochemistry; Kidney; Lipid Peroxidation; Liver; Lung; Male; Malondialdehyde; Melatonin; Nitrates; Rats; Rats, Sprague-Dawley; Shock; Tyrosine; Zymosan | 1999 |
Beneficial effects of Mn(III)tetrakis (4-benzoic acid) porphyrin (MnTBAP), a superoxide dismutase mimetic, in zymosan-induced shock.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Bilirubin; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Energy Metabolism; Free Radical Scavengers; Immunohistochemistry; L-Lactate Dehydrogenase; Lung; Male; Malondialdehyde; Metalloporphyrins; NAD; Nitrates; Peroxidase; Rats; Rats, Sprague-Dawley; Shock; Superoxide Dismutase; Tyrosine; Zymosan | 1999 |
A comparison of neonatal and adult multiorgan failure in a rat model.
Topics: Age Factors; Animals; Animals, Newborn; Disease Models, Animal; Disease Progression; Kidney; Liver; Lung; Male; Multiple Organ Failure; Organ Size; Rats; Rats, Sprague-Dawley; Spleen; Surgical Procedures, Operative; Zymosan | 2000 |
The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis.
Topics: Administration, Oral; Animals; Arthritis; Cannabidiol; Cannabis; Cattle; Cell Division; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Granulocytes; Hindlimb; Interferon-gamma; Joints; Lipopolysaccharides; Lymph Nodes; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Peritoneum; Reactive Oxygen Species; Synovial Fluid; Th1 Cells; Tumor Necrosis Factor-alpha; Zymosan | 2000 |
21-NO-prednisolone is a novel nitric oxide-releasing derivative of prednisolone with enhanced anti-inflammatory properties.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Granuloma; Humans; Inflammation; Interleukin-1; Leukocytes, Mononuclear; Male; Mice; Nitric Oxide; Peritonitis; Prednisolone; Receptors, Cell Surface; Treatment Outcome; Zymosan | 2000 |
Role of sensitized pelvic nerve afferents from the inflamed rat colon in the maintenance of visceral hyperalgesia.
Topics: Afferent Pathways; Animals; Colon; Disease Models, Animal; Hyperalgesia; Hypogastric Plexus; Inflammation; Male; Neurons, Afferent; Nociceptors; Pelvic Pain; Pressure; Rats; Rats, Sprague-Dawley; Zymosan | 2000 |
Tempering the temptation to treat with tempol.
Topics: Animals; Antioxidants; Cyclic N-Oxides; Disease Models, Animal; Humans; Multiple Organ Failure; Rats; Shock, Septic; Spin Labels; Zymosan | 2001 |
GPI 6150, a poly (ADP-ribose) polymerase inhibitor, exhibits an anti-inflammatory effect in rat models of inflammation.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Benzopyrans; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Enzyme Inhibitors; Hindlimb; Inflammation; Isoquinolines; Liver; Lung; Male; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Long-Evans; Survival Rate; Zymosan | 2001 |
Zymosan modulates CD44 isoform expression in a murine model of inflammation resembling rheumatoid arthritis synovitis.
Topics: Animals; Antibodies, Monoclonal; Arthritis, Rheumatoid; Blotting, Southern; Chemotaxis, Leukocyte; Disease Models, Animal; Exons; Exudates and Transudates; Flow Cytometry; Gene Expression; Hyaluronan Receptors; Isomerism; Leukocytes; Mice; RNA, Messenger; Synovitis; Tumor Necrosis Factor-alpha; Zymosan | 2001 |
Celecoxib loses its anti-inflammatory efficacy at high doses through activation of NF-kappaB.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Inflammation; Interleukin-1; Isoenzymes; Male; NF-kappa B; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Transcription, Genetic; Tumor Necrosis Factor-alpha; Zymosan | 2001 |
A new model of sciatic inflammatory neuritis (SIN): induction of unilateral and bilateral mechanical allodynia following acute unilateral peri-sciatic immune activation in rats.
Topics: Acute Disease; Animals; Catheterization; Disease Models, Animal; Dose-Response Relationship, Drug; HMGB1 Protein; Hyperalgesia; Lymph Nodes; Male; Organ Size; Physical Stimulation; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Sciatica; Specific Pathogen-Free Organisms; Spleen; Zymosan | 2001 |
Anti-inflammatory effects of somatostatin analogs on zymosan-induced earlobe inflammation in mice: comparison with dexamethasone and ketoprofen.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Blood Vessels; Dexamethasone; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Ear, External; Edema; Hormones; Inflammation; Ketoprofen; Male; Mice; Mice, Inbred BALB C; Octreotide; Regional Blood Flow; Skin; Somatostatin; Zymosan | 2001 |
Sciatic inflammatory neuritis (SIN): behavioral allodynia is paralleled by peri-sciatic proinflammatory cytokine and superoxide production.
Topics: Animals; Behavior, Animal; Cytokines; Disease Models, Animal; Flow Cytometry; Gelatin Sponge, Absorbable; Immunohistochemistry; Interleukin-1; Interleukin-6; Leukocytes; Luminescent Measurements; Lymphocyte Count; Male; Pain Measurement; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sciatic Neuropathy; Specific Pathogen-Free Organisms; Superoxides; Tumor Necrosis Factor-alpha; Wallerian Degeneration; Zymosan | 2001 |
Vitamin E uncouples joint destruction and clinical inflammation in a transgenic mouse model of rheumatoid arthritis.
Topics: Animals; Antioxidants; Arthritis, Rheumatoid; Body Weight; Disease Models, Animal; Glutathione; Hydrogen Peroxide; Interleukin-1; Isoprostanes; Joints; Leukocytes; Luminescent Measurements; Mice; Mice, Inbred NOD; Mice, Transgenic; Oxidation-Reduction; Tumor Necrosis Factor-alpha; Vitamin E; Zymosan | 2002 |
Morphine attenuates pain and prevents inflammation in experimental peritonitis.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Dose-Response Relationship, Drug; Enkephalins; Leukocytes; Morphine; Pain; Peritonitis; Protein Precursors; Zymosan | 2002 |
Factors determining the susceptibility of mice to experimental phycomycosis.
Topics: Age Factors; Animals; Azathioprine; Brain; Cortisone; Cyclophosphamide; Disease Models, Animal; Female; Ferrous Compounds; Fungi; gamma-Globulins; Immune Sera; Immunity; Kidney; Male; Mice; Mice, Inbred C3H; Mycoses; Sex Factors; Species Specificity; Zymosan | 1975 |
Comparative effects of drugs on four paw oedema models in the rat.
Topics: Animals; Anti-Inflammatory Agents; Antibodies, Anti-Idiotypic; Arthus Reaction; Disease Models, Animal; Drug Evaluation, Preclinical; Edema; Immunoglobulin G; Kaolin; Male; Ovalbumin; Rats; Stomach Ulcer; Zymosan | 1979 |
Evaluation of the mechanism of zymosan-induced resistance to experimental peritonitis.
Topics: Animals; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Hemoglobins; Humans; Injections, Intraperitoneal; Leukocytes; Monocytes; Mononuclear Phagocyte System; Peritonitis; Phagocytosis; Rats; Zymosan | 1978 |
Interactions of leukocyte integrins with intercellular adhesion molecule 1 in the production of inflammatory vascular injury in vivo. The Shwartzman reaction revisited.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Bacterial Toxins; Blood Vessels; Cell Adhesion; Cell Adhesion Molecules; Complement Activation; Disease Models, Animal; Endotoxins; Enterotoxins; Female; Hemorrhage; IgA Vasculitis; Integrins; Intercellular Adhesion Molecule-1; Leukocytes; Models, Biological; Rabbits; Skin; Zymosan | 1992 |
Lung oxidant changes after zymosan peritonitis: relationship between physiologic and biochemical changes.
Topics: Animals; Blood Gas Analysis; Catalase; Disease Models, Animal; Evaluation Studies as Topic; Glutathione; Glutathione Disulfide; Inflammation; Lipid Peroxidation; Male; Malondialdehyde; Oxygen Consumption; Peritonitis; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Time Factors; Xanthine Dehydrogenase; Xanthine Oxidase; Zymosan | 1992 |
The anti-inflammatory effect of erythromycin in zymosan-induced peritonitis of mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Ascitic Fluid; Blood Proteins; Dinoprostone; Disease Models, Animal; Erythromycin; Female; Mice; Peritonitis; Time Factors; Treatment Failure; Zymosan | 1992 |
Superoxide dismutase and catalase in an experimental model of multiple organ failure.
Topics: Animals; Catalase; Disease Models, Animal; Free Radical Scavengers; Lipid Peroxidation; Male; Multiple Organ Failure; Rats; Rats, Inbred Strains; Superoxide Dismutase; Zymosan | 1992 |
Tumour necrosis factor production in a rat airpouch model of inflammation: role of eicosanoids.
Topics: Animals; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Indomethacin; Inflammation; Kinetics; Leukotriene B4; Lipopolysaccharides; Lipoxygenase Inhibitors; Male; Rats; Rats, Inbred Strains; SRS-A; Tumor Necrosis Factor-alpha; Zymosan | 1991 |
A comparison of the anti-inflammatory activity of selective 5-lipoxygenase inhibitors with dexamethasone and colchicine in a model of zymosan induced inflammation in the rat knee joint and peritoneal cavity.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arthritis; Benzeneacetamides; Calcimycin; Colchicine; Dexamethasone; Dinoprostone; Disease Models, Animal; Hydroxamic Acids; Inflammation; Kinetics; Knee Joint; Leukocytes; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Peritonitis; Pyrazoles; Rats; Zymosan | 1991 |
A comparative study of the cellular, exudative and histological responses to carrageenan, dextran and zymosan in the mouse.
Topics: Animals; Carrageenan; Dextrans; Disease Models, Animal; Exudates and Transudates; Female; Inflammation; Leukocyte Count; Leukocytes; Mice; Mice, Inbred BALB C; Zymosan | 1991 |
[Rat multiple organ failure model caused by zymosan injections: a pathomorphological study].
Topics: Animals; Disease Models, Animal; Male; Microscopy, Electron; Multiple Organ Failure; Rats; Rats, Inbred Strains; Reference Standards; Zymosan | 1991 |
Role of pulmonary inflammation in altered airway responsiveness in three sheep models of acute lung injury.
Topics: Animals; Bronchi; Disease Models, Animal; Endotoxins; Female; Lung; Lung Diseases; Male; Mast Cells; Neutrophils; Plasma; Sheep; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Zymosan inflammation: a new method suitable for evaluating new antiinflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Disease Models, Animal; Edema; Female; Inflammation; Rats; Rats, Inbred Strains; Zymosan | 1991 |
Extracellular phospholipase A2 activity in two in vivo models of inflammation.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Ascitic Fluid; Calcium; Caseins; Disease Models, Animal; Extracellular Space; Hydrogen-Ion Concentration; Kinetics; Male; Mice; Peritoneal Lavage; Peritonitis; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Lew; Zymosan | 1990 |
Tumour necrosis factor alpha (TNF-alpha) and interleukin 6 in a zymosan-induced shock model.
Topics: Animals; Antibodies, Monoclonal; Complement Activation; Disease Models, Animal; Female; In Vitro Techniques; Interleukin-6; Macrophages; Mice; Peritoneal Cavity; Random Allocation; Shock, Septic; Tumor Necrosis Factor-alpha; Zymosan | 1990 |
SOD in rat models of shock and organ failure.
Topics: Animals; Body Weight; Cattle; Disease Models, Animal; Lipid Peroxidation; Liver; Male; Multiple Organ Failure; Peritonitis; Rats; Rats, Inbred Strains; Shock; Shock, Septic; Superoxide Dismutase; Zymosan | 1990 |
Immobilization aggravates cartilage damage during antigen-induced arthritis in mice. Attachment of polymorphonuclear leukocytes to articular cartilage.
Topics: Animals; Antigen-Antibody Complex; Antigens; Arthritis; Arthritis, Experimental; Cartilage, Articular; Cell Adhesion; Complement System Proteins; Disease Models, Animal; Immobilization; Male; Mice; Microscopy, Electron; Neutrophils; Zymosan | 1990 |
Development of a bacteria-independent model of the multiple organ failure syndrome.
Topics: Animals; Bacteria; Disease Models, Animal; Hemodynamics; Intestines; Kidney; Liver; Lung; Lymph Nodes; Mineral Oil; Multiple Organ Failure; Rats; Rats, Inbred Strains; Respiration; Sepsis; Zymosan | 1989 |
Superoxide production by neutrophils in a model of adult respiratory distress syndrome.
Topics: Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Endotoxins; Escherichia coli; Kinetics; Leukocyte Count; Lipopolysaccharides; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rats; Respiratory Distress Syndrome; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Time Factors; Zymosan | 1988 |
Early diagnosis of adult respiratory distress syndrome: an experimental model of complement-mediated pulmonary injury.
Topics: Animals; Carbon Dioxide; Cell Aggregation; Complement Activation; Disease Models, Animal; Male; Neutrophils; Oxygen; Partial Pressure; Rabbits; Respiratory Distress Syndrome; Zymosan | 1988 |
Systemic complement activation produces hemodynamic changes characteristic of sepsis.
Topics: Animals; Blood Pressure; Cardiac Output; Complement Activation; Disease Models, Animal; Female; Heart Rate; Hematocrit; Hemodynamics; Infections; Kidney; Liver; Rats; Rats, Inbred Strains; Vascular Resistance; Zymosan | 1988 |
A modified mouse air pouch model for evaluating the effects of compounds on granuloma induced cartilage degradation.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cartilage; Collagen; Dexamethasone; Disease Models, Animal; Female; Femur Head; Granuloma; Male; Mice; Prednisolone; Proteoglycans; Rats; Zymosan | 1988 |
Multiple-organ failure and sepsis without bacteria. An experimental model.
Topics: Animals; Blood Chemical Analysis; Disease Models, Animal; Germ-Free Life; Leukocyte Count; Male; Multiple Organ Failure; Organ Size; Paraffin; Rats; Rats, Inbred Strains; Zymosan | 1986 |
Interaction of cells with immune complexes: adherence, release of constituents, and tissue injury.
Topics: Alkaline Phosphatase; Animals; Antigen-Antibody Complex; Arteritis; Arthus Reaction; Basement Membrane; Cytoplasmic Granules; Disease Models, Animal; Glomerulonephritis; Glucuronidase; Immune System Diseases; Immunoglobulins; Lysosomes; Microscopy, Electron; Neutrophils; Phagocytosis; Rabbits; Urinary Bladder; Zymosan | 1971 |
Experiences with lymphocyte immunotherapy in experimental tumor systems.
Topics: Adjuvants, Immunologic; Animals; Disease Models, Animal; Evaluation Studies as Topic; Female; Lymph Nodes; Lymphatic System; Lymphocytes; Mammary Neoplasms, Experimental; Methylcholanthrene; Mice; Neoplasm Transplantation; Rats; Spleen; Thymus Gland; Tissue Extracts; Zymosan | 1971 |
Renovation of Intestinal Barrier by Polydatin in Experimentally Induced Ulcerative Colitis: Comparative Ultrastructural Study with L-Carnosine.
Topics: Animals; Carnosine; Colitis, Ulcerative; Colon; Disease Models, Animal; Glucosides; Humans; Rats; Stilbenes | 2021 |
Corrective Effect of Verbascoside on Histomorphological Differences and Oxidative Stress in Colon Mucosa of Rats in Which Colon Ischemia-Reperfusion Injury was Induced.
Topics: Animals; Antioxidants; Colon; Disease Models, Animal; Glucosides; Intestinal Mucosa; Male; Oxidative Stress; Phenols; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2021 |
Salidroside attenuates cardiac dysfunction in a rat model of diabetes.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Diabetic Cardiomyopathies; Disease Models, Animal; Glucosides; Inflammation; Male; Myocytes, Cardiac; Oxidative Stress; Phenols; Rats; Rats, Sprague-Dawley; Signal Transduction; Streptozocin; TOR Serine-Threonine Kinases | 2022 |
SGLT2 inhibitor ipragliflozin exerts antihyperglycemic effects via the blood glucose-dependent increase in urinary glucose excretion in type 2 diabetic mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose Tolerance Test; Glucosides; Humans; Male; Mice; Renal Elimination; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2021 |
Direct Blood Pressure-Independent Anti-Fibrotic Effects by the Selective Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone in Progressive Models of Kidney Fibrosis.
Topics: Actins; Adaptor Proteins, Signal Transducing; Albuminuria; Animals; Benzhydryl Compounds; Blood Pressure; Calcium-Binding Proteins; Collagen; Creatinine; Disease Models, Animal; Fibrosis; Gene Expression; Glucosides; Kidney; Kidney Diseases; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Mineralocorticoid Receptor Antagonists; Monocytes; Myofibroblasts; Naphthyridines; Reperfusion Injury; RNA, Messenger; Serpin E2; Sodium-Glucose Transporter 2 Inhibitors; Ureteral Obstruction | 2021 |
Empagliflozin maintains capillarization and improves cardiac function in a murine model of left ventricular pressure overload.
Topics: Animals; Benzhydryl Compounds; Biomarkers; Blood Pressure; Cardiotonic Agents; Disease Management; Disease Models, Animal; Gene Expression Profiling; Glucosides; Heart Failure; Immunohistochemistry; Metabolome; Metabolomics; Mice; Microcirculation; Models, Biological; Norepinephrine; Sodium-Glucose Transporter 2 Inhibitors; Ventricular Dysfunction, Left | 2021 |
Salidroside-pretreated mesenchymal stem cells contribute to neuroprotection in cerebral ischemic injury in vitro and in vivo.
Topics: Animals; Apoptosis; Biomarkers; Brain Ischemia; CA1 Region, Hippocampal; Cell Survival; Cells, Cultured; Disease Management; Disease Models, Animal; Fluorescent Antibody Technique; Glucosides; Immunohistochemistry; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Neuroprotection; Phenols; Rats | 2021 |
Mizagliflozin, a selective SGLT1 inhibitor, improves vascular cognitive impairment in a mouse model of small vessel disease.
Topics: Animals; Carotid Artery, Common; Cerebral Small Vessel Diseases; Cerebrovascular Circulation; Cognition; Cognitive Dysfunction; Cytokines; Disease Models, Animal; Glucosides; Hippocampus; Inflammation; Mice; Morris Water Maze Test; Neurons; Phlorhizin; Pyrazoles; Sodium-Glucose Transporter 1 | 2021 |
Antihypertensive and metabolic effects of empagliflozin in Ren-2 transgenic rats, an experimental non-diabetic model of hypertension.
Topics: Adiposity; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Antioxidants; Benzhydryl Compounds; Blood Pressure; Disease Models, Animal; Energy Metabolism; Glucosides; Hypertension; Male; Rats, Sprague-Dawley; Rats, Transgenic; Renin; Weight Loss | 2021 |
Empagliflozin protects the heart against ischemia/reperfusion-induced sudden cardiac death.
Topics: Animals; Arrhythmias, Cardiac; Benzhydryl Compounds; Death, Sudden, Cardiac; Disease Models, Animal; Glucosides; Heart Rate; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardial Reperfusion Injury; Myocytes, Cardiac; Phosphorylation; Rats, Sprague-Dawley; Signal Transduction; Sodium-Glucose Transporter 2 Inhibitors | 2021 |
Complex Positive Effects of SGLT-2 Inhibitor Empagliflozin in the Liver, Kidney and Adipose Tissue of Hereditary Hypertriglyceridemic Rats: Possible Contribution of Attenuation of Cell Senescence and Oxidative Stress.
Topics: 3T3-L1 Cells; Adipose Tissue; Administration, Oral; Animals; Benzhydryl Compounds; Cell Survival; Cellular Senescence; Disease Models, Animal; Down-Regulation; Dyslipidemias; Gluconeogenesis; Glucosides; Hep G2 Cells; Humans; Hypertriglyceridemia; Hypoglycemic Agents; Insulin Resistance; Kidney; Lipogenesis; Liver; Male; Mice; Oxidative Stress; Rats; Sodium-Glucose Transporter 2 Inhibitors; Treatment Outcome; Up-Regulation; Weight Gain | 2021 |
Peripheral combination treatment of leptin and an SGLT2 inhibitor improved glucose metabolism in insulin-dependent diabetes mellitus mice.
Topics: Administration, Oral; Animals; Diabetes Mellitus, Type 1; Disease Models, Animal; Drug Therapy, Combination; Glucose; Glucosides; Infusions, Intravenous; Leptin; Male; Mice, Inbred C57BL; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2021 |
Neuroprotective effect of paeoniflorin in the mouse model of Parkinson's disease through α-synuclein/protein kinase C δ subtype signaling pathway.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Synuclein; Animals; Annexin A5; Anti-Inflammatory Agents, Non-Steroidal; Antiparkinson Agents; Apoptosis; Disease Models, Animal; Glucosides; Mice; Microscopy, Electron, Transmission; Monoterpenes; Neurotoxins; Parkinsonian Disorders; Protein Kinase C-delta; Rotarod Performance Test; Selegiline; Substantia Nigra | 2021 |
Salidroside orchestrates metabolic reprogramming by regulating the Hif-1α signalling pathway in acute mountain sickness.
Topics: Acute Disease; Altitude Sickness; Animals; Brain; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Glucosides; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice; Mice, Inbred C57BL; PC12 Cells; Phenols; Rats; Rhodiola; Signal Transduction | 2021 |
Effects of GLP-1RA and SGLT2i, Alone or in Combination, on Mouse Models of Type 2 Diabetes Representing Different Disease Stages.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Therapy, Combination; Glucagon-Like Peptide-1 Receptor; Glucosides; Hypoglycemic Agents; Insulin-Secreting Cells; Liraglutide; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2021 |
In a Prediabetic Model, Empagliflozin Improves Hepatic Lipid Metabolism Independently of Obesity and before Onset of Hyperglycemia.
Topics: Animals; Benzhydryl Compounds; Cytochrome P-450 Enzyme System; Disease Models, Animal; Disease Progression; Glucosides; Hyperglycemia; Hyperlipoproteinemia Type IV; Inflammation Mediators; Insulin Resistance; Lipid Metabolism; Liver; Male; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; Prediabetic State; Rats; Rats, Mutant Strains; Rats, Wistar; Sodium-Glucose Transporter 2 Inhibitors | 2021 |
Paeoniflorin ameliorates airway inflammation and immune response in ovalbumin induced asthmatic mice: From oxidative stress to autophagy.
Topics: Animals; Asthma; Autophagy; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Glucosides; Immunity; Inflammation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Monoterpenes; Ovalbumin; Oxidative Stress | 2022 |
Pharmacological Approaches to Attenuate Inflammation and Obesity with Natural Products Formulations by Regulating the Associated Promoting Molecular Signaling Pathways.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Angiogenesis Inhibitors; Animals; Biological Products; Disease Models, Animal; Diterpenes, Kaurane; Drug Compounding; Drug Synergism; Female; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Lipid Metabolism; Lipogenesis; Lipolysis; Mice; Mice, Inbred ICR; Obesity; Oleanolic Acid; Phytotherapy; RNA, Messenger; Saponins; Signal Transduction; Stevia; Tea | 2021 |
Effect of Dapagliflozin and Magnesium Supplementation on Renal Magnesium Handling and Magnesium Homeostasis in Metabolic Syndrome.
Topics: Animals; Benzhydryl Compounds; Diet, Carbohydrate Loading; Dietary Supplements; Disease Models, Animal; Fructose; Glucosides; Homeostasis; Insulin Resistance; Kidney; Kidney Tubules; Magnesium; Magnesium Deficiency; Magnesium Sulfate; Metabolic Syndrome; Rats; Sodium-Glucose Transporter 2 Inhibitors; TRPM Cation Channels | 2021 |
Salidroside Attenuates Airway Inflammation and Remodeling via the miR-323-3p/SOCS5 Axis in Asthmatic Mice.
Topics: Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Glucosides; Inflammation; Lung; Mice; Mice, Inbred BALB C; MicroRNAs; Ovalbumin; Phenols; Signal Transduction; Suppressor of Cytokine Signaling Proteins | 2022 |
Gastrodin attenuates perfluorooctanoic acid-induced liver injury by regulating gut microbiota composition in mice.
Topics: Animals; Benzyl Alcohols; Caprylates; Cecum; Cytokines; Disease Models, Animal; Fatty Acids, Volatile; Fluorocarbons; Gastrointestinal Microbiome; Glucosides; Hepatomegaly; Inflammation Mediators; Liver; Male; Mice, Inbred C57BL; Oxidative Stress; Phylogeny; Protective Agents | 2021 |
Paeoniflorin ameliorates chronic stress-induced depression-like behavior in mice model by affecting ERK1/2 pathway.
Topics: Animals; Behavior, Animal; Butadienes; Cell Count; Chronic Disease; Depression; Disease Models, Animal; Gene Expression Regulation; Glucosides; Hippocampus; Male; MAP Kinase Signaling System; Mice, Inbred C57BL; Monoterpenes; Neurons; Nitriles; Stress, Psychological | 2021 |
Effect of Hibiscus syriacus Linnaeus extract and its active constituent, saponarin, in animal models of stress-induced sleep disturbances and pentobarbital-induced sleep.
Topics: Animals; Apigenin; Cerebral Cortex; Corticosterone; Disease Models, Animal; Electroencephalography; Glucosides; Hibiscus; Male; Mice, Inbred C57BL; Mice, Inbred ICR; Pentobarbital; Plant Extracts; Preoptic Area; Proto-Oncogene Proteins c-fos; Rats, Sprague-Dawley; Receptors, GABA-A; Sleep; Sleep Aids, Pharmaceutical; Sleep Wake Disorders; Stress, Psychological | 2022 |
Specnuezhenide reduces carbon tetrachloride-induced liver injury in mice through inhibition of oxidative stress and hepatocyte apoptosis.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Disease Models, Animal; Dose-Response Relationship, Drug; Glucosides; Hepatocytes; Liver Diseases; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Pyrans; Signal Transduction | 2022 |
Sodium-Glucose Co-Transporter 2 (SGLT2) Inhibitor Dapagliflozin Stabilizes Diabetes-Induced Atherosclerotic Plaque Instability.
Topics: Animals; Benzhydryl Compounds; Constriction, Pathologic; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucose; Glucosides; Humans; Hypoglycemic Agents; Mice; Plaque, Atherosclerotic; Sodium; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Streptozocin | 2022 |
Hepatoprotective effects of gemigliptin and empagliflozin in a murine model of diet-induced non-alcoholic fatty liver disease.
Topics: Amino Acids; Animals; Benzhydryl Compounds; Choline; Cytokines; Diet, High-Fat; Disease Models, Animal; Disease Progression; Glucosides; Inflammation; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Liver; Macrophage Activation; Male; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Phosphorylation; Piperidones; Protective Agents; Pyrimidines | 2022 |
Total glucosides of paeony ameliorates oxidative stress, apoptosis and inflammatory response by regulating the Smad7‑TGF‑β pathway in allergic rhinitis.
Topics: Animals; Apoptosis; Biomarkers; Cytokines; Disease Models, Animal; Glucosides; Immunoglobulin E; Immunohistochemistry; Male; Mice; Oxidative Stress; Paeonia; Plant Extracts; Rhinitis, Allergic; Signal Transduction; Smad7 Protein; Transforming Growth Factor beta | 2022 |
The dynamic interplay between AMPK/NFκB signaling and NLRP3 is a new therapeutic target in inflammation: Emerging role of dapagliflozin in overcoming lipopolysaccharide-mediated lung injury.
Topics: Acute Lung Injury; AMP-Activated Protein Kinases; Animals; Benzhydryl Compounds; Disease Models, Animal; Glucosides; Inflammation; Lipopolysaccharides; Male; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium-Glucose Transporter 2 Inhibitors | 2022 |
Protective effects of Dapagliflozin on the vulnerability of ventricular arrhythmia in rats with pulmonary artery hypertension induced by monocrotaline.
Topics: Animals; Arrhythmias, Cardiac; Benzhydryl Compounds; Disease Models, Animal; Glucosides; Hypertension, Pulmonary; Male; Monocrotaline; Pulmonary Artery; Rats; Rats, Sprague-Dawley | 2022 |
Treatment Combining Focused Ultrasound with Gastrodin Alleviates Memory Deficit and Neuropathology in an Alzheimer's Disease-Like Experimental Mouse Model.
Topics: Alzheimer Disease; Animals; Benzyl Alcohols; Blood-Brain Barrier; Brain; Combined Modality Therapy; Disease Models, Animal; Glucosides; Maze Learning; Memory Disorders; Mice; Neuroprotective Agents; Ultrasonography, Interventional | 2022 |
Acteoside, the Main Bioactive Compound in
Topics: Animals; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Flowers; Gastrointestinal Microbiome; Glucosides; Mice; Mice, Inbred C57BL; Phenols | 2022 |
Corilagin Ameliorates Con A-Induced Hepatic Injury by Restricting M1 Macrophage Polarization.
Topics: Animals; Biomarkers; Chemical and Drug Induced Liver Injury; Concanavalin A; Cytokines; Disease Models, Animal; Disease Susceptibility; Glucosides; Hydrolyzable Tannins; Inflammation Mediators; Liver Function Tests; Macrophage Activation; Macrophages; Male; Mice; Treatment Outcome | 2021 |
Effects of a novel selective PPARα modulator, statin, sodium-glucose cotransporter 2 inhibitor, and combinatorial therapy on the liver and vasculature of medaka nonalcoholic steatohepatitis model.
Topics: Animal Fins; Animals; Animals, Genetically Modified; Benzhydryl Compounds; Benzoxazoles; Butyrates; Diet, High-Fat; Disease Models, Animal; Exome Sequencing; Gene Ontology; Glucosides; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Non-alcoholic Fatty Liver Disease; Oryzias; PPAR alpha; Quinolines; Reverse Transcriptase Polymerase Chain Reaction; Sodium-Glucose Transporter 2 Inhibitors; Transcriptome | 2022 |
Empagliflozin Enhances Autophagy, Mitochondrial Biogenesis, and Antioxidant Defense and Ameliorates Renal Ischemia/Reperfusion in Nondiabetic Rats.
Topics: Animals; Antioxidants; Apoptosis; Autophagy; Benzhydryl Compounds; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Glucosides; Interleukin-1beta; Kidney Diseases; Male; Malondialdehyde; Organelle Biogenesis; Oxidative Stress; Rats; Rats, Wistar; Reperfusion Injury; Signal Transduction; Sodium-Glucose Transporter 2 Inhibitors; Treatment Outcome; Tumor Necrosis Factor-alpha | 2022 |
Agnuside mitigates OVA-LPS induced perturbed lung homeostasis via modulating inflammatory, autophagy, apoptosis-fibrosis response and myeloid lineages in mice model of allergic asthma.
Topics: Animals; Apoptosis; Asthma; Autophagy; Bronchoalveolar Lavage Fluid; Cell Lineage; Cytokines; Disease Models, Animal; Fibrosis; Glucosides; Homeostasis; Lung; Mice; Mice, Inbred BALB C; Ovalbumin | 2022 |
Exploring the synergistic and complementary effects of berberine and paeoniflorin in the treatment of type 2 diabetes mellitus by network pharmacology.
Topics: Animals; Berberine; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Drugs, Chinese Herbal; Glucosides; Humans; Hypoglycemic Agents; Male; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Monoterpenes; Network Pharmacology; Phytotherapy | 2022 |
SGLT2 inhibitors therapy protects glucotoxicity-induced β-cell failure in a mouse model of human KATP-induced diabetes through mitigation of oxidative and ER stress.
Topics: Administration, Oral; Animals; Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus; Disease Models, Animal; Endoplasmic Reticulum Stress; Female; Gain of Function Mutation; Glucosides; Humans; Infant, Newborn; Infant, Newborn, Diseases; Insulin-Secreting Cells; KATP Channels; Male; Mice; Mice, Transgenic; Oxidative Stress; Protective Agents; Signal Transduction; Sodium-Glucose Transporter 2 Inhibitors; Treatment Outcome | 2022 |
Ipragliflozin attenuates non-alcoholic steatohepatitis development in an animal model.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Fasting; Gene Expression Profiling; Gene Expression Regulation; Glucosides; Hepatocytes; Hypoglycemic Agents; Interleukin-1beta; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Non-alcoholic Fatty Liver Disease; Signal Transduction; Streptozocin; Superoxide Dismutase; Thiophenes; Tumor Necrosis Factor-alpha | 2022 |
Secoisolariciresinol diglucoside ameliorates high fat diet-induced colon inflammation and regulates gut microbiota in mice.
Topics: Animals; Anti-Inflammatory Agents; Butylene Glycols; Colitis; Diet, High-Fat; Disease Models, Animal; Gastrointestinal Microbiome; Glucosides; Inflammation; Male; Mice; Mice, Inbred C57BL | 2022 |
Anti-Septic Functions of Cornuside against HMGB1-Mediated Severe Inflammatory Responses.
Topics: Animals; Cell Adhesion; Cell Movement; Cells, Cultured; Cytokines; Disease Models, Animal; Glucosides; HMGB1 Protein; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Male; Mice; Mice, Inbred C57BL; Pyrans; Sepsis; Signal Transduction | 2022 |
Preventive empagliflozin activity on acute acetic acid-induced ulcerative colitis in rats via modulation of SIRT-1/PI3K/AKT pathway and improving colon barrier.
Topics: Acetic Acid; Animals; Benzhydryl Compounds; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Glucosides; NF-kappa B; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Sirtuins | 2022 |
Empagliflozin Reverses Late Na
Topics: Animals; Benzhydryl Compounds; Disease Models, Animal; Glucosides; Heart Failure; Humans; Mice; Myocytes, Cardiac; Stroke Volume | 2022 |
Dapagliflozin, sildenafil and their combination in monocrotaline-induced pulmonary arterial hypertension.
Topics: Animals; Benzhydryl Compounds; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Glucosides; Humans; Hypertension, Pulmonary; Monocrotaline; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats; Sildenafil Citrate; Vascular Remodeling | 2022 |
Verbascoside administered intrathecally attenuates hyperalgesia via activating mu-opioid receptors in a rat chronic constriction injury model.
Topics: Analgesics; Animals; Biological Products; Constriction; Disease Models, Animal; Glucosides; Humans; Hyperalgesia; Male; Neuralgia; Phenols; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, mu | 2022 |
Gastrodin Alleviates Acetaminophen-Induced Liver Injury in a Mouse Model Through Inhibiting MAPK and Enhancing Nrf2 Pathways.
Topics: Acetaminophen; Animals; Antioxidants; Benzyl Alcohols; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Disease Models, Animal; Glucosides; Liver; Mice; NF-E2-Related Factor 2; Oxidative Stress | 2022 |
Trifolirhizin regulates the balance of Th17/Treg cells and inflammation in the ulcerative colitis mice through inhibiting the TXNIP-mediated activation of NLRP3 inflammasome.
Topics: AMP-Activated Protein Kinases; Animals; Carrier Proteins; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Glucosides; Heterocyclic Compounds, 4 or More Rings; Inflammasomes; Inflammation; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; T-Lymphocytes, Regulatory; Th17 Cells; Thioredoxins | 2022 |
Paeoniflorin attenuates monocrotaline-induced pulmonary arterial hypertension in rats by suppressing TAK1-MAPK/NF-κB pathways.
Topics: Animals; Disease Models, Animal; Endothelial Cells; Glucosides; Hypertension, Pulmonary; MAP Kinase Kinase Kinases; Monocrotaline; Monoterpenes; NF-kappa B; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats | 2022 |
Skin Dryness Induced in the KK-Ay/TaJcl Type 2 Diabetes Mouse Model Deteriorates Following Dapagliflozin Administration.
Topics: Animals; Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucosides; Hyaluronic Acid; Hypoglycemic Agents; Mice; Sodium-Glucose Transporter 2 Inhibitors | 2022 |
The efficacy of a paeoniflorin-sodium alginate-gelatin skin scaffold for the treatment of diabetic wound: An in vivo study in a rat model.
Topics: Alginates; Animals; Collagen; Diabetes Complications; Diabetes Mellitus; Disease Models, Animal; Gelatin; Glucosides; Microvessels; Monoterpenes; Printing, Three-Dimensional; Rats; Skin; Tissue Scaffolds; Wound Healing; Wounds and Injuries | 2022 |
Paeoniflorin prevents aberrant proliferation and differentiation of intestinal stem cells by controlling C1q release from macrophages in chronic colitis.
Topics: Animals; Cell Proliferation; Colitis; Complement C1q; Dextran Sulfate; Disease Models, Animal; Glucosides; Inflammation; Interleukin-10; Intestinal Mucosa; Macrophages; Mice; Mice, Inbred C57BL; Monoterpenes; Stem Cells | 2022 |
Polydatin alleviates DSS- and TNBS-induced colitis by suppressing Th17 cell differentiation via directly inhibiting STAT3.
Topics: Animals; Cell Differentiation; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Glucosides; Inflammatory Bowel Diseases; Mice; Mice, Inbred C57BL; STAT3 Transcription Factor; Stilbenes; T-Lymphocytes, Regulatory; Th17 Cells; Trinitrobenzenesulfonic Acid | 2022 |
Potential Chemoprevention of Paeoniflorin in Colitis-Associated Colorectal Cancer by Network Pharmacology, Molecular Docking, and In Vivo Experiment.
Topics: Animals; Cell Transformation, Neoplastic; Chemoprevention; Colitis-Associated Neoplasms; Colorectal Neoplasms; Disease Models, Animal; Glucosides; Interleukin-6; Mice; Molecular Docking Simulation; Monoterpenes; Network Pharmacology; STAT3 Transcription Factor | 2022 |
Prdx6-induced inhibition of ferroptosis in epithelial cells contributes to liquiritin-exerted alleviation of colitis.
Topics: Amino Acids; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis; Dextran Sulfate; Disease Models, Animal; Epithelial Cells; Ferritins; Ferroptosis; Flavanones; Glucosides; Iron; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Peroxiredoxin VI | 2022 |
Empagliflozin improves cardiac mitochondrial function and survival through energy regulation in a murine model of heart failure.
Topics: Animals; Benzhydryl Compounds; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose; Glucosides; Heart Failure; Male; Mice; Mitochondria; Sodium-Glucose Transporter 2 Inhibitors | 2022 |
Paeoniflorin exhibits antidepressant activity in rats with postpartum depression via the TSPO and BDNF‑mTOR pathways.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Carrier Proteins; Corticosterone; Depression; Depression, Postpartum; Disease Models, Animal; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Fluoxetine; Glucosides; Hippocampus; Humans; Monoterpenes; Pregnancy; Pregnanolone; Progesterone; Rats; Receptors, GABA-A; Stress, Psychological; Sucrose; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha | 2022 |
Empagliflozin Preserves Skeletal Muscle Function in a HFpEF Rat Model.
Topics: Animals; Benzhydryl Compounds; Disease Models, Animal; Drinking Water; Glucose; Glucosides; Heart Failure; Lipids; Muscle, Skeletal; Obesity; Rats; Saponins; Sodium; Stroke Volume; Ventricular Function, Left | 2022 |
Paeoniflorin Attenuates Lipopolysaccharide-Induced Cognitive Dysfunction by Inhibition of Amyloidogenesis in Mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cognitive Dysfunction; Disease Models, Animal; Glucosides; Lipopolysaccharides; Maze Learning; Memory Disorders; Mice; Mice, Transgenic; Monoterpenes | 2023 |
Effects and mechanisms of salidroside on the behavior of SPS-induced PTSD rats.
Topics: Animals; Disease Models, Animal; Glucosides; Hippocampus; Humans; Phenols; Rats; Stress Disorders, Post-Traumatic | 2023 |
Total Glucosides of White Paeony Capsule ameliorates Parkinson's disease-like behavior in MPTP-induced mice model by regulating LRRK2/alpha-synuclein signaling.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Synuclein; Animals; Disease Models, Animal; Dopaminergic Neurons; Glucosides; Mice; Mice, Inbred C57BL; Neuroinflammatory Diseases; Neuroprotective Agents; Paeonia; Parkinson Disease | 2024 |
Neuroprotective effect of Verbascoside on hypoxic-ischemic brain damage in neonatal rat.
Topics: Animals; Animals, Newborn; Autophagy; Disease Models, Animal; Glucosides; Hypoxia-Ischemia, Brain; Neuroprotective Agents; Oxidative Stress; Phenols; Rats; Rats, Sprague-Dawley; Recovery of Function | 2019 |
Dapagliflozin improves left ventricular remodeling and aorta sympathetic tone in a pig model of heart failure with preserved ejection fraction.
Topics: Animals; Aorta; Benzhydryl Compounds; Biomarkers; Blood Pressure; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cytokines; Disease Models, Animal; Female; Fibrosis; Glucosides; Heart Failure; Hypertension; Inflammation Mediators; Lipids; Nitric Oxide; Norepinephrine; Sodium-Glucose Transporter 2 Inhibitors; Sus scrofa; Sympathetic Nervous System; Ventricular Function, Left; Ventricular Remodeling | 2019 |
Polydatin prevents LPS-induced acute kidney injury through inhibiting inflammatory and oxidative responses.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Glucosides; Heme Oxygenase-1; Interleukin-1beta; Interleukin-6; Kidney; Lipopolysaccharides; Membrane Proteins; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Peptide Fragments; Signal Transduction; Stilbenes; Tumor Necrosis Factor-alpha | 2019 |
Protective effects of polydatin on LPS-induced endometritis in mice.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Endometritis; Female; Glucosides; Heme Oxygenase-1; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Membrane Proteins; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; NF-kappa B; Peroxidase; Protective Agents; Signal Transduction; Stilbenes; Tumor Necrosis Factor-alpha; Uterus; Vagina | 2019 |
Verbascoside attenuates acute inflammatory injury in experimental cerebral hemorrhage by suppressing TLR4.
Topics: Animals; Antioxidants; Apoptosis; Brain Edema; Cerebral Hemorrhage; Disease Models, Animal; Glucosides; Inflammation; Male; Mice, Inbred C57BL; Mice, Knockout; Neurons; Neuroprotective Agents; Phenols; Plants, Medicinal; Toll-Like Receptor 4 | 2019 |
Inhibition of sodium-glucose cotransporter 2 ameliorates renal injury in a novel medaka model of nonalcoholic steatohepatitis-related kidney disease.
Topics: Animals; Benzhydryl Compounds; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Glucose; Glucosides; Glutamate Plasma Membrane Transport Proteins; Hypoglycemic Agents; Kidney; Kidney Diseases; Non-alcoholic Fatty Liver Disease; Oryzias; Sodium; Sodium-Glucose Transporter 2 Inhibitors | 2019 |
Pharmacokinetic comparative study of tetramethylpyrazine and ferulic acid and their compatibility with different concentration of gastrodin and gastrodigenin on blood-stasis migraine model by blood-brain microdialysis method.
Topics: Administration, Oral; Animals; Benzyl Alcohols; Blood-Brain Barrier; Cold Temperature; Coumaric Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drugs, Chinese Herbal; Extracellular Fluid; Gastrodia; Glucosides; Humans; Ligusticum; Male; Microdialysis; Migraine Disorders; Permeability; Pyrazines; Rats; Specific Pathogen-Free Organisms; Vasoconstriction | 2020 |
Acteoside inhibits inflammatory response via JAK/STAT signaling pathway in osteoarthritic rats.
Topics: Animals; Cell Proliferation; Chondrocytes; Disease Models, Animal; Drugs, Chinese Herbal; Glucosides; Humans; Interferon-gamma; Janus Kinases; Ligustrum; Male; Osteoarthritis; Phenols; Rats; Rats, Sprague-Dawley; Signal Transduction; STAT Transcription Factors; Tumor Necrosis Factor-alpha | 2019 |
Inflammation inhibition and gut microbiota regulation by TSG to combat atherosclerosis in ApoE
Topics: Administration, Oral; Animals; Aorta; Atherosclerosis; Chemokine CCL2; Diet, High-Fat; Disease Models, Animal; Drugs, Chinese Herbal; Gastrointestinal Microbiome; Glucosides; Humans; Inflammation; Intercellular Adhesion Molecule-1; Lipoproteins, LDL; Male; Mice; Mice, Knockout, ApoE; Polygonum; Stilbenes; Triglycerides; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2020 |
Antithrombotic Effects of Paeoniflorin from
Topics: Adult; Animals; Blood Platelets; Calcium; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrinolytic Agents; Glucosides; Humans; Male; Monoterpenes; Paeonia; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Rats; Stress, Mechanical; von Willebrand Factor; Young Adult | 2019 |
Icariin-induced miR-875-5p attenuates epithelial-mesenchymal transition by targeting hedgehog signaling in liver fibrosis.
Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Collagen; Disease Models, Animal; Epithelial-Mesenchymal Transition; Flavonoids; Gene Expression; Glucosides; Hedgehog Proteins; Liver Cirrhosis; Mice, Inbred C57BL; MicroRNAs; Molecular Targeted Therapy; Phytotherapy; Signal Transduction; Zinc Finger Protein GLI1 | 2020 |
CP-25 exerts anti-angiogenic effects on a rat model of adjuvant-induced arthritis by promoting GRK2-induced downregulation of CXCR4-ERK1/2 signaling in endothelial cells.
Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Disease Models, Animal; G-Protein-Coupled Receptor Kinase 2; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; MAP Kinase Signaling System; Monoterpenes; Rats; Rats, Sprague-Dawley; Receptors, CXCR4; Signal Transduction | 2019 |
Long-term protective efficacy with a BCG-prime ID93/GLA-SE boost regimen against the hyper-virulent Mycobacterium tuberculosis strain K in a mouse model.
Topics: Animals; Antigens, Bacterial; BCG Vaccine; Beijing; Disease Models, Animal; Glucosides; Humans; Immunization, Secondary; Lipid A; Mice; Mycobacterium tuberculosis; Th1 Cells; Tuberculosis; Tuberculosis Vaccines; Vaccination | 2019 |
Empagliflozin and Dulaglutide are Effective against Obesity-induced Airway Hyperresponsiveness and Fibrosis in A Murine Model.
Topics: Animals; Benzhydryl Compounds; Cell Differentiation; Cytokines; Diet, High-Fat; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Glucagon-Like Peptides; Glucosides; Immunoglobulin Fc Fragments; Mice; Obesity; Recombinant Fusion Proteins; Respiratory Hypersensitivity; RNA, Messenger; Th1 Cells; Th17 Cells | 2019 |
Salidroside Restores an Anti-inflammatory Endothelial Phenotype by Selectively Inhibiting Endothelial Complement After Oxidative Stress.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis Regulatory Proteins; Brain; Cell Line; Coculture Techniques; Complement Activation; Complement C3; Complement Inactivating Agents; Disease Models, Animal; Endothelial Cells; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Infarction, Middle Cerebral Artery; Inflammation Mediators; Male; Mice; Oxidative Stress; Phenols; Phenotype; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction | 2020 |
Salidroside mitigates skeletal muscle atrophy in rats with cigarette smoke-induced COPD by up-regulating myogenin and down-regulating myostatin expression.
Topics: Animals; Antioxidants; Disease Models, Animal; Down-Regulation; Glucosides; Lung; Male; Muscle, Skeletal; Muscular Atrophy; Myogenin; Myostatin; Nicotiana; Phenols; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Rats; Rats, Wistar; Smoke; Smoking; Up-Regulation | 2019 |
Gastrodin Attenuates Neuronal Apoptosis and Neurological Deficits after Experimental Intracerebral Hemorrhage.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Behavior, Animal; Benzyl Alcohols; Brain Edema; Cells, Cultured; Cerebral Cortex; Cerebral Hemorrhage; Disease Models, Animal; Glucosides; Male; Motor Activity; Neurons; Neuroprotective Agents; Oxidative Stress; Rats, Sprague-Dawley; Signal Transduction | 2020 |
Polydatin Inhibits NLRP3 Inflammasome in Dry Eye Disease by Attenuating Oxidative Stress and Inhibiting the NF-κB Pathway.
Topics: Animals; Disease Models, Animal; Dry Eye Syndromes; Fallopia japonica; Glucosides; Inflammasomes; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Plant Roots; Rats; Signal Transduction; Stilbenes | 2019 |
Empagliflozin restores lowered exercise endurance capacity via the activation of skeletal muscle fatty acid oxidation in a murine model of heart failure.
Topics: 3-Hydroxybutyric Acid; Adipose Tissue; Animals; Benzhydryl Compounds; Blood Glucose; Disease Models, Animal; Fatty Acids; Glucosides; Heart Failure; Insulin; Male; Mice; Mice, Inbred C57BL; Mitochondria; Muscle Strength; Muscle, Skeletal; Oxidation-Reduction; Oxidative Phosphorylation; Physical Conditioning, Animal; Physical Endurance; Recovery of Function; Sodium-Glucose Transporter 2 Inhibitors | 2020 |
Gastrodin Alleviates Vascular Dementia in a 2-VO-Vascular Dementia Rat Model by Altering Amyloid and Tau Levels.
Topics: Amyloid beta-Peptides; Animals; Benzyl Alcohols; Brain Ischemia; Carotid Stenosis; Dementia, Vascular; Disease Models, Animal; Glucosides; Hippocampus; Male; Maze Learning; Memory; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; tau Proteins | 2020 |
Empagliflozin, a sodium glucose co-transporter-2 inhibitor, alleviates atrial remodeling and improves mitochondrial function in high-fat diet/streptozotocin-induced diabetic rats.
Topics: Animals; Atrial Fibrillation; Atrial Function, Left; Atrial Remodeling; Benzhydryl Compounds; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Glucosides; Heart Rate; Male; Membrane Potential, Mitochondrial; Mitochondria, Heart; Mitochondrial Proteins; Organelle Biogenesis; Oxidative Stress; Rats, Sprague-Dawley; Signal Transduction; Sodium-Glucose Transporter 2 Inhibitors; Streptozocin | 2019 |
Protective effects of Salidroside on cardiac function in mice with myocardial infarction.
Topics: Animals; Apoptosis; Cardiotonic Agents; Coronary Vessels; Cytokines; Disease Models, Animal; Fibrosis; Glucosides; Heart; Ligation; Male; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Neovascularization, Physiologic; Phenols; Ventricular Remodeling | 2019 |
Renoprotective Effects Of Isoliquiritin Against Cationic Bovine Serum Albumin-Induced Membranous Glomerulonephritis In Experimental Rat Model Through Its Anti-Oxidative And Anti-Inflammatory Properties.
Topics: Animals; Biomarkers; Cations; Chalcone; Disease Models, Animal; Dose-Response Relationship, Drug; Glomerulonephritis, Membranous; Glucosides; Inflammation; Injections, Intravenous; Male; Molecular Structure; Oxidative Stress; Protective Agents; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Structure-Activity Relationship | 2019 |
In vivo anti-inflammatory and anti-allergic activities of cynaroside evaluated by using hydrogel formulations.
Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Disease Models, Animal; Drug Compounding; Drug Liberation; Edema; Glucosides; Hydrogels; Luteolin; Male; Mice, Inbred C57BL; Oxazolone; Proliferating Cell Nuclear Antigen | 2020 |
HDAC Inhibition Prevents Primary Cone Degeneration Even After the Onset of Degeneration.
Topics: Animals; Disease Models, Animal; Glucosides; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Mice; Retina; Retinal Cone Photoreceptor Cells; Retinal Degeneration | 2019 |
Protective Effect of Paeoniflorin on Acute Cerebral Infarction in Rats.
Topics: Acute Disease; Animals; Brain; Cerebral Infarction; Disease Models, Animal; Glucosides; Lipid Peroxidation; Male; Malondialdehyde; Monoterpenes; Neurons; Neuroprotective Agents; Nimodipine; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase | 2020 |
FA-97, a New Synthetic Caffeic Acid Phenethyl Ester Derivative, Protects against Oxidative Stress-Mediated Neuronal Cell Apoptosis and Scopolamine-Induced Cognitive Impairment by Activating Nrf2/HO-1 Signaling.
Topics: Alzheimer Disease; Animals; Apoptosis; Caffeic Acids; Cognitive Dysfunction; Disease Models, Animal; Glucosides; Heme Oxygenase-1; Humans; Male; Mice; Mice, Inbred Strains; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; PC12 Cells; Phenylethyl Alcohol; Rats; RNA, Small Interfering; Scopolamine; Signal Transduction | 2019 |
Ipragliflozin Ameliorates Endoplasmic Reticulum Stress and Apoptosis through Preventing Ectopic Lipid Deposition in Renal Tubules.
Topics: Animals; Apoptosis; Disease Models, Animal; Down-Regulation; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Glucosides; Heat-Shock Proteins; Male; Mice; Non-alcoholic Fatty Liver Disease; Renal Insufficiency, Chronic; Thiophenes; Transcription Factor CHOP; Triglycerides | 2019 |
Butyrate attenuated fat gain through gut microbiota modulation in db/db mice following dapagliflozin treatment.
Topics: Adipose Tissue; Animals; Benzhydryl Compounds; Butyric Acid; Disease Models, Animal; Gastrointestinal Microbiome; Glucose; Glucosides; Liver; Mice; Obesity; Sodium-Glucose Transporter 2 Inhibitors; Weight Gain | 2019 |
Sodium-glucose cotransporter 2 inhibitor Dapagliflozin attenuates diabetic cardiomyopathy.
Topics: Angiotensin II; Animals; Benzhydryl Compounds; Biomarkers; Blood Glucose; Calcium Channels, L-Type; Calcium Signaling; Cells, Cultured; Diabetes Mellitus; Diabetic Cardiomyopathies; Disease Models, Animal; Fibrosis; Glucosides; Inflammation Mediators; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Rats, Sprague-Dawley; Sodium-Calcium Exchanger; Sodium-Glucose Transporter 2 Inhibitors; Sodium-Hydrogen Exchanger 1; Ventricular Function, Left | 2020 |
Inhibition of tumor necrosis factor-α enhanced the antifibrotic effect of empagliflozin in an animal model with renal insulin resistance.
Topics: Animals; Benzhydryl Compounds; Disease Models, Animal; Glucosides; Infliximab; Insulin Resistance; Kidney Diseases; Male; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2020 |
Alleviating effect of paeoniflorin-6'-O-benzene sulfonate in antigen-induced experimental Sjögren's syndrome by modulating B lymphocyte migration via CXCR5-GRK2-ERK/p38 signaling pathway.
Topics: Animals; Antigens; Antirheumatic Agents; B-Lymphocytes; Cell Line, Tumor; Cell Movement; Cell Survival; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Female; G-Protein-Coupled Receptor Kinase 2; Glucosides; Humans; Mice, Inbred C57BL; Monoterpenes; p38 Mitogen-Activated Protein Kinases; Receptors, CXCR5; Salivary Glands; Sjogren's Syndrome; Spleen; T-Lymphocytes | 2020 |
Lansoprazole enhances the antidiabetic effect of dapagliflozin in fortified diet-fed streptozotocin-treated diabetic rats.
Topics: Animals; Benzhydryl Compounds; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus, Experimental; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Food, Fortified; Glucose Transporter Type 2; Glucosides; Hypoglycemic Agents; Inflammation Mediators; Insulin Resistance; Lansoprazole; Male; Oxidative Stress; Pancreas; PPAR gamma; Random Allocation; Rats; Rats, Wistar; Sodium-Glucose Transporter 2 Inhibitors | 2020 |
Salidroside improves high-fat diet-induced non-alcoholic steatohepatitis by regulating the gut microbiota-bile acid-farnesoid X receptor axis.
Topics: Animals; Bile Acids and Salts; Diet, High-Fat; Disease Models, Animal; Gastrointestinal Microbiome; Glucosides; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Phenols; Receptors, Cytoplasmic and Nuclear; Triglycerides | 2020 |
Tetrahydroxystilbene Glucoside Ameliorates Infrasound-Induced Central Nervous System (CNS) Injury by Improving Antioxidant and Anti-Inflammatory Capacity.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Central Nervous System; Cytokines; Disease Models, Animal; Glucosides; Inflammation; Male; Mice; Stilbenes; Ultrasonic Waves | 2020 |
Neuroprotective Effects of Salidroside in a Mouse Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognitive Dysfunction; Disease Models, Animal; Glucosides; Mice, Inbred C57BL; Mice, Transgenic; Neuroprotective Agents; Phenols; Phosphatidylinositol 3-Kinases; Signal Transduction; TOR Serine-Threonine Kinases | 2020 |
Load-independent effects of empagliflozin contribute to improved cardiac function in experimental heart failure with reduced ejection fraction.
Topics: Animals; Benzhydryl Compounds; Calcium Signaling; Disease Models, Animal; Glucosides; Heart Failure; Myocardial Infarction; Myocardium; Rats, Inbred F344; Sodium-Glucose Transporter 2 Inhibitors; Stroke Volume; Ventricular Function, Left; Ventricular Pressure | 2020 |
Paeoniflorin alleviates lipopolysaccharide-induced disseminated intravascular coagulation by inhibiting inflammation and coagulation activation.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Blood Coagulation; Disease Models, Animal; Disseminated Intravascular Coagulation; Glucosides; Inflammation; Lipopolysaccharides; Macrophages; Mice; Monoterpenes; NF-kappa B; RAW 264.7 Cells; Signal Transduction; Tumor Necrosis Factor-alpha | 2020 |
Empagliflozin attenuates transient cerebral ischemia/reperfusion injury in hyperglycemic rats via repressing oxidative-inflammatory-apoptotic pathway.
Topics: Animals; Apoptosis; Benzhydryl Compounds; Disease Models, Animal; Gliclazide; Glucosides; Hyperglycemia; Hypoglycemic Agents; Inflammation; Ischemic Attack, Transient; Male; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar | 2020 |
Empagliflozin improved systolic blood pressure, endothelial dysfunction and heart remodeling in the metabolic syndrome ZSF1 rat.
Topics: Animals; Benzhydryl Compounds; Biomarkers; Blood Glucose; Blood Pressure; Cellular Senescence; Disease Models, Animal; Endothelium, Vascular; Glucosides; Metabolic Syndrome; Obesity; Rats, Zucker; Sodium-Glucose Transporter 2 Inhibitors; Systole; Ventricular Function, Left; Ventricular Remodeling | 2020 |
Salidroside suppresses group 2 innate lymphoid cell-mediated allergic airway inflammation by targeting IL-33/ST2 axis.
Topics: Animals; Asthma; Cytokines; Disease Models, Animal; Female; Glucosides; Humans; Hypersensitivity; Immunity, Innate; Immunosuppressive Agents; Interleukin-1 Receptor-Like 1 Protein; Interleukin-33; Lymphocytes; Mice; Mice, Inbred C57BL; Phenols; Pneumonia; Respiratory System; Rhodiola; Signal Transduction; Th2 Cells | 2020 |
Purified oleocanthal and ligstroside protect against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing.
Topics: Aging; Aldehydes; Alzheimer Disease; Animals; Brain; Cell Line; Cell Respiration; Cyclopentane Monoterpenes; Disease Models, Animal; Female; Glucosides; Humans; Mice; Mitochondria; Neurons; Neuroprotective Agents; Phenols; Pyrans | 2020 |
Arctiin protects rat heart against ischemia/reperfusion injury via a mechanism involving reduction of necroptosis.
Topics: Animals; Cardiotonic Agents; Cell Line; Disease Models, Animal; Drugs, Chinese Herbal; Furans; Glucosides; Humans; Male; Mitochondria; Myocardial Reperfusion Injury; Myocytes, Cardiac; Necroptosis; Protein Kinases; Protein Serine-Threonine Kinases; Rats; Reactive Oxygen Species; Receptor-Interacting Protein Serine-Threonine Kinases; Signal Transduction | 2020 |
Effects of Sodium-Glucose Co-transporter 2 Inhibition with Empaglifozin on Renal Structure and Function in Non-diabetic Rats with Left Ventricular Dysfunction After Myocardial Infarction.
Topics: Animals; Benzhydryl Compounds; Biomarkers; Disease Models, Animal; Diuresis; Glucosides; Kidney; Male; Myocardial Infarction; Rats, Sprague-Dawley; Sodium-Glucose Transporter 2 Inhibitors; Ventricular Dysfunction, Left; Ventricular Function, Left | 2020 |
Study on the Changes of Chemical Constituents in Different Compatibilities of Ginseng-Prepared Rehmannia Root and Their Effects on Bone Marrow Inhibition after Chemotherapy.
Topics: Animals; Antineoplastic Agents, Alkylating; Bone Marrow; Cyclophosphamide; Disease Models, Animal; Dose-Response Relationship, Drug; Furaldehyde; Ginsenosides; Glucosides; Injections, Intraperitoneal; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred BALB C; Molecular Structure; Panax; Phenols; Plant Roots; Rehmannia; Structure-Activity Relationship | 2020 |
Treatment of Brain Edema by Wogonoside Is Associated with Inhibition of Neuronal Apoptosis and SIRT1 Activation in Rats.
Topics: Animals; Apoptosis; Brain; Brain Edema; Disease Models, Animal; Flavanones; Glucosides; Humans; Male; Rats; Sirtuin 1; Tumor Suppressor Protein p53 | 2020 |
Osteoarthritis is Prevented in Rats by Verbascoside via Nuclear Factor kappa B (NF-κB) Pathway Downregulation.
Topics: Animals; Cartilage, Articular; Cytokines; Disease Models, Animal; Down-Regulation; Glucosides; Immunosuppressive Agents; NF-kappa B; Osteoarthritis; Phenols; Purinergic P2X Receptor Antagonists; Quality of Life; Rats | 2020 |
Paeoniflorin Ameliorates Chronic Hypoxia/SU5416-Induced Pulmonary Arterial Hypertension by Inhibiting Endothelial-to-Mesenchymal Transition.
Topics: Animals; Cells, Cultured; Chronic Disease; Disease Models, Animal; Endothelial Cells; Epithelial-Mesenchymal Transition; Glucosides; Humans; Hypoxia; Indoles; Injections, Subcutaneous; Male; Monoterpenes; Oxygen; Pulmonary Arterial Hypertension; Pyrroles; Rats; Rats, Sprague-Dawley | 2020 |
Empagliflozin reduces vascular damage and cognitive impairment in a mixed murine model of Alzheimer's disease and type 2 diabetes.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzhydryl Compounds; Brain; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Glucosides; Male; Mice; Mice, Transgenic | 2020 |
Effect of liquiritin on neuroendocrine-immune network in menopausal rat model.
Topics: Animals; Disease Models, Animal; Female; Flavanones; Glucosides; Glycyrrhiza; Menopause; Neurosecretory Systems; Rats; Rats, Wistar | 2020 |
Paeoniflorin ameliorates antipsychotic-induced hyperprolactinemia in rats by attenuating impairment of the dopamine D2 receptor and TGF-β1 signaling pathways in the hypothalamus and pituitary.
Topics: Animals; Antipsychotic Agents; Biomarkers; Cell Line, Tumor; Disease Models, Animal; Female; Glucosides; Hyperprolactinemia; Hypothalamus; Monoterpenes; Olanzapine; Pituitary Gland; Prolactin; Rats, Sprague-Dawley; Receptors, Dopamine D2; Signal Transduction; Transforming Growth Factor beta1 | 2020 |
Dapagliflozin and Ticagrelor Have Additive Effects on the Attenuation of the Activation of the NLRP3 Inflammasome and the Progression of Diabetic Cardiomyopathy: an AMPK-mTOR Interplay.
Topics: AMP-Activated Protein Kinases; Animals; Benzhydryl Compounds; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Disease Models, Animal; Disease Progression; Enzyme Activation; Fibrosis; Glucosides; Inflammasomes; Male; Mechanistic Target of Rapamycin Complex 2; Mice, Inbred C57BL; Myocytes, Cardiac; NLR Family, Pyrin Domain-Containing 3 Protein; Purinergic P2Y Receptor Antagonists; Signal Transduction; Sodium-Glucose Transporter 2 Inhibitors; Stroke Volume; Ticagrelor; TOR Serine-Threonine Kinases; Ventricular Function, Left; Ventricular Remodeling | 2020 |
Paeoniflorin Attenuates Myocardial Fibrosis in Isoprenaline-induced Chronic Heart Failure Rats via Inhibiting P38 MAPK Pathway.
Topics: Animals; Cardiomyopathies; Disease Models, Animal; Down-Regulation; Fibrosis; Gene Expression Regulation; Glucosides; Heart Function Tests; Isoproterenol; Male; MAP Kinase Signaling System; Monoterpenes; Rats; Transforming Growth Factor beta1 | 2020 |
Salidroside Alleviates Cartilage Degeneration Through NF-κB Pathway in Osteoarthritis Rats.
Topics: Animals; Cartilage, Articular; Cell Proliferation; Chondrocytes; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glucosides; Injections, Intraperitoneal; NF-kappa B; Osteoarthritis; Phenols; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2020 |
Tetrahydroxy stilbene glycoside alleviated inflammatory damage by mitophagy via AMPK related PINK1/Parkin signaling pathway.
Topics: Alzheimer Disease; AMP-Activated Protein Kinases; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents; Cell Line, Tumor; Cognitive Dysfunction; Disease Models, Animal; Gene Expression Regulation; Glucosides; Humans; Inflammasomes; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Mitochondria; Mitophagy; Neurons; Neuroprotective Agents; NLR Family, Pyrin Domain-Containing 3 Protein; Primary Cell Culture; Protein Kinases; RNA, Small Interfering; Signal Transduction; Stilbenes; Ubiquitin-Protein Ligases | 2020 |
Paeoniflorin exerts neuroprotective effects in a transgenic mouse model of Alzheimer's disease via activation of adenosine A
Topics: Adenosine; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Glucosides; Memory; Mice, Transgenic; Monoterpenes; Neuroprotective Agents; Receptor, Adenosine A1 | 2020 |
Comparative efficacy of empagliflozin and drugs of baseline therapy in post-infarct heart failure in normoglycemic rats.
Topics: Animals; Benzhydryl Compounds; Bisoprolol; Cardiovascular Agents; Chronic Disease; Disease Models, Animal; Exercise Tolerance; Fosinopril; Glucosides; Heart Failure; Male; Myocardial Infarction; Rats, Wistar; Sodium-Glucose Transporter 2 Inhibitors; Spironolactone; Ventricular Dysfunction, Left; Ventricular Function, Left | 2020 |
2,3,5,4'-tetrahydroxystilbence-2-O-β-D-glucoside attenuates hepatic steatosis via IKKβ/NF-κB and Keap1-Nrf2 pathways in larval zebrafish.
Topics: Animals; Cholesterol, Dietary; Disease Models, Animal; Glucosides; I-kappa B Kinase; Kelch-Like ECH-Associated Protein 1; Lipid Metabolism; NF-E2-Related Factor 2; NF-kappa B; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Signal Transduction; Stilbenes; Zebrafish; Zebrafish Proteins | 2020 |
Empagliflozin improves endothelial and cardiomyocyte function in human heart failure with preserved ejection fraction via reduced pro-inflammatory-oxidative pathways and protein kinase Gα oxidation.
Topics: Aged; Animals; Anti-Inflammatory Agents; Antioxidants; Benzhydryl Compounds; Cyclic GMP-Dependent Protein Kinase Type I; Disease Models, Animal; Endothelial Cells; Female; Glucosides; Heart Failure; Humans; Inflammation Mediators; Male; Middle Aged; Myocytes, Cardiac; Oxidative Stress; Rats, Zucker; Signal Transduction; Sodium-Glucose Transporter 2 Inhibitors; Stroke Volume; Ventricular Function, Left | 2021 |
Effects of gastrodin against carbon tetrachloride induced kidney inflammation and fibrosis in mice associated with the AMPK/Nrf2/HMGB1 pathway.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Benzyl Alcohols; Carbon Tetrachloride; Disease Models, Animal; Fibrosis; Glucosides; HMGB1 Protein; Inflammation; Kidney Diseases; Male; Mice; Mice, Inbred ICR; NF-E2-Related Factor 2; Phytotherapy; Protein Kinases | 2020 |
Total glucosides of paeony (TGP) alleviates Sjogren's syndrome through inhibiting inflammatory responses in mice.
Topics: Animals; Anti-Inflammatory Agents; Autoimmune Diseases; Body Weight; Cytokines; Disease Models, Animal; Gene Expression Regulation; Glucosides; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Paeonia; Saliva; Sjogren's Syndrome; Submandibular Gland | 2020 |
Empagliflozin prevents doxorubicin-induced myocardial dysfunction.
Topics: Animals; Benzhydryl Compounds; Cardiomyopathies; Cardiotoxicity; Diastole; Disease Models, Animal; Doxorubicin; Extracellular Signal-Regulated MAP Kinases; Fibrosis; Glucosides; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Sodium-Glucose Transporter 2 Inhibitors; Systole; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2020 |
Serotonergically dependent antihyperalgesic and antiallodynic effects of isoliquiritin in a mouse model of neuropathic pain.
Topics: Analgesics; Animals; Behavior, Animal; Brain; Chalcone; Disease Models, Animal; Glucosides; Hyperalgesia; Male; Mice, Inbred C57BL; Neuralgia; Pain Threshold; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists; Spinal Cord | 2020 |
Empagliflozin Protects Cardiac Mitochondrial Fatty Acid Metabolism in a Mouse Model of Diet-Induced Lipid Overload.
Topics: Animals; Benzhydryl Compounds; Diet, High-Fat; Disease Models, Animal; Dyslipidemias; Energy Metabolism; Glucosides; Male; Mice, Inbred C57BL; Mitochondria, Heart; Oxidation-Reduction; Palmitates; Sodium-Glucose Transporter 2 Inhibitors | 2020 |
Salidroside ameliorates Parkinson's disease by inhibiting NLRP3-dependent pyroptosis.
Topics: Animals; Disease Models, Animal; Glucosides; Male; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Parkinson Disease; Phenols; Pyroptosis; Signal Transduction | 2020 |
Empagliflozin alleviates neuronal apoptosis induced by cerebral ischemia/reperfusion injury through HIF-1α/VEGF signaling pathway.
Topics: Administration, Oral; Animals; Apoptosis; Benzhydryl Compounds; Brain Ischemia; Disease Models, Animal; Glucosides; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Rats; Rats, Wistar; Reperfusion Injury; Signal Transduction; Vascular Endothelial Growth Factors | 2020 |
Biomolecular network-based synergistic drug combination discovery: a combination of paeoniflorin and liquiritin alleviates neuropathic pain by inhibiting neuroinflammation via suppressing the chemokine signaling pathway.
Topics: Animals; Chemokines; Disease Models, Animal; Drug Discovery; Drug Therapy, Combination; Flavanones; Glucosides; Humans; Monoterpenes; Neuralgia; Rats; Signal Transduction | 2020 |
Arctiin abrogates osteoclastogenesis and bone resorption via suppressing RANKL-induced ROS and NFATc1 activation.
Topics: Animals; Antioxidant Response Elements; Bone Density Conservation Agents; Bone Resorption; Calcium Signaling; Disease Models, Animal; Female; Furans; Glucosides; Kelch-Like ECH-Associated Protein 1; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-E2-Related Factor 2; NFATC Transcription Factors; Osteoclasts; Osteogenesis; Osteoporosis; Ovariectomy; RANK Ligand; RAW 264.7 Cells; Reactive Oxygen Species | 2020 |
Therapeutic Effects of Salidroside on Cognitive Ability in Rats with Experimental Vascular Dementia.
Topics: Animals; Brain; Cognition; Dementia, Vascular; Disease Models, Animal; Glucosides; Male; Malondialdehyde; Maze Learning; Morris Water Maze Test; Neuroprotective Agents; Oxidative Stress; Phenols; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2020 |
Total glucosides of paeony (TGP) alleviates constipation and intestinal inflammation in mice induced by Sjögren's syndrome.
Topics: Animals; Anti-Inflammatory Agents; Colitis; Colon; Constipation; Defecation; Disease Models, Animal; Female; Gastrointestinal Motility; Glucosides; Inflammation Mediators; Laxatives; Mice, Inbred C57BL; Paeonia; Plant Extracts; Proto-Oncogene Proteins c-kit; Signal Transduction; Sjogren's Syndrome; Stem Cell Factor | 2020 |
Dapagliflozin, a sodium glucose cotransporter 2 inhibitors, protects cardiovascular function in type-2 diabetic murine model.
Topics: Animals; Benzhydryl Compounds; Blood Glucose; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Glucosides; Metformin; Random Allocation; Rats; Sodium-Glucose Transporter 2 Inhibitors; Triglycerides | 2020 |
Total glucosides of herbaceous peony (Paeonia lactiflora Pall.) flower attenuate adenine- and ethambutol-induced hyperuricaemia in rats.
Topics: Adenine; Animals; Biomarkers; Disease Models, Animal; Down-Regulation; Ethambutol; Flowers; Glucosides; Hyperuricemia; Kidney; Male; Paeonia; Plant Extracts; Rats, Wistar; Uric Acid; Uricosuric Agents | 2020 |
Acute dapagliflozin administration exerts cardioprotective effects in rats with cardiac ischemia/reperfusion injury.
Topics: Animals; Apoptosis; Arrhythmias, Cardiac; Benzhydryl Compounds; Disease Models, Animal; Energy Metabolism; Glucosides; Male; Mitochondria, Heart; Mitochondrial Dynamics; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Rats, Wistar; Sodium-Glucose Transporter 2 Inhibitors; Ventricular Dysfunction, Left; Ventricular Function, Left | 2020 |
Effects of Gastrodin against Lead-Induced Brain Injury in Mice Associated with the Wnt/Nrf2 Pathway.
Topics: Animals; Benzyl Alcohols; Brain Injuries; Disease Models, Animal; Glucosides; Hippocampus; Lead; Lead Poisoning; Male; Mice; Mice, Inbred ICR; Neuroprotective Agents; NF-E2-Related Factor 2; Wnt Signaling Pathway | 2020 |
Empagliflozin suppresses inflammation and protects against acute septic renal injury.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Benzhydryl Compounds; Disease Models, Animal; Glucosides; Inflammation; Male; Mice; Mice, Inbred C57BL; Sepsis; Shock, Septic; Sodium-Glucose Transporter 2 Inhibitors | 2021 |
Involvement of FGF-2 modulation in the antidepressant-like effects of liquiritin in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Calcium-Binding Proteins; Cytokines; Dendritic Spines; Depression; Disease Models, Animal; Fibroblast Growth Factor 2; Flavanones; Food Preferences; Glucosides; Hippocampus; Locomotion; Male; Mice, Inbred ICR; Microfilament Proteins; Microglia; Swimming | 2020 |
Anti-inflammatory effect of stevioside abates Freund's complete adjuvant (FCA)-induced adjuvant arthritis in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arthritis, Experimental; Biomarkers; Cytokines; Disease Models, Animal; Diterpenes, Kaurane; Freund's Adjuvant; Glucosides; Inflammation; Rats; Rats, Sprague-Dawley | 2020 |
CP-25 alleviates antigen-induced experimental Sjögren's syndrome in mice by inhibiting JAK1-STAT1/2-CXCL13 signaling and interfering with B-cell migration.
Topics: Animals; B-Lymphocytes; Cell Movement; Cells, Cultured; Chemokine CXCL13; Disease Models, Animal; Female; Glucosides; Humans; Janus Kinase 1; Mice; Mice, Inbred C57BL; Monoterpenes; Signal Transduction; Sjogren's Syndrome; STAT Transcription Factors; Submandibular Gland | 2021 |
The cardioprotective potential of the sodium-glucose cotransporter 2 inhibitor empagliflozin in donor heart preservation.
Topics: Animals; Benzhydryl Compounds; Disease Models, Animal; Glucosides; Heart Transplantation; Organ Preservation; Rats, Wistar; Sodium-Glucose Transporter 2 Inhibitors; Tissue Donors | 2020 |
Dapagliflozin improves behavioral dysfunction of Huntington's disease in rats via inhibiting apoptosis-related glycolysis.
Topics: Animals; Apoptosis; Autophagy; Behavior, Animal; Benzhydryl Compounds; Disease Models, Animal; Glucosides; Glycolysis; Huntington Disease; Inflammation; Male; Maze Learning; Rats; Rats, Wistar; Sodium-Glucose Transporter 2 Inhibitors | 2020 |
Attenuation of Inflammatory Symptoms by Icariside B2 in Carrageenan and LPS-Induced Inflammation Models via Regulation of MAPK/NF-κB Signaling Cascades.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Cyclohexanones; Disease Models, Animal; Edema; Epimedium; Gene Expression Regulation; Glucosides; Lipopolysaccharides; MAP Kinase Signaling System; Mice; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; NF-kappa B; Norisoprenoids; Phosphorylation; Plant Extracts | 2020 |
Gastrodin Pretreatment Protects Liver Against Ischemia-Reperfusion Injury via Activation of the Nrf2/HO-1 Pathway.
Topics: Animals; Antioxidants; Benzyl Alcohols; Cytokines; Disease Models, Animal; Down-Regulation; Drugs, Chinese Herbal; Glucosides; Heme Oxygenase-1; Liver; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phytotherapy; Preoperative Care; Reperfusion Injury; Signal Transduction; Toll-Like Receptor 4 | 2020 |
Salidroside Attenuates Doxorubicin-Induced Cardiac Dysfunction Partially Through Activation of QKI/FoxO1 Pathway.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cardiotoxicity; Cell Line; Disease Models, Animal; Doxorubicin; Forkhead Box Protein O1; Glucosides; Heart Diseases; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Nerve Tissue Proteins; Oxidative Stress; Phenols; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA-Binding Proteins; Signal Transduction; Ventricular Function, Left | 2021 |
NMR-Based Metabonomic Study Reveals Intervention Effects of Polydatin on Potassium Oxonate-Induced Hyperuricemia in Rats.
Topics: Animals; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Drugs, Chinese Herbal; Glucosides; Humans; Hyperuricemia; Kidney; Male; Metabolomics; Oxonic Acid; Rats; Rats, Sprague-Dawley; Stilbenes; Uric Acid | 2020 |
Nodakenin alleviated obstructive nephropathy through blunting Snail1 induced fibrosis.
Topics: Angelica; Animals; Anti-Inflammatory Agents; Coumarins; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Glucosides; Humans; Kidney; Kidney Failure, Chronic; Macrophages; Mice; NF-kappa B; Phosphorylation; Plant Roots; Signal Transduction; Smad3 Protein; Snail Family Transcription Factors; Transforming Growth Factor beta1; Ureteral Obstruction | 2020 |
Dapagliflozin promotes beta cell regeneration by inducing pancreatic endocrine cell phenotype conversion in type 2 diabetic mice.
Topics: Animals; Benzhydryl Compounds; Blood Glucose; C-Peptide; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Endocrine Cells; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Secreting Cells; Glucose; Glucosides; Insulin; Insulin-Secreting Cells; Male; Mice; Proprotein Convertase 1; Regeneration; Sodium-Glucose Transporter 2 Inhibitors | 2020 |
5,5-Difluoro- and 5-Fluoro-5-methyl-hexose-based C-Glucosides as potent and orally bioavailable SGLT1 and SGLT2 dual inhibitors.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Disease Models, Animal; Drug Design; Glucose Tolerance Test; Glucosides; Half-Life; Halogenation; Humans; Hypoglycemic Agents; Inhibitory Concentration 50; Mice; Mice, Inbred C57BL; Microsomes; Rats; Rats, Sprague-Dawley; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Structure-Activity Relationship | 2020 |
Effect of Vicenin-2 on ovariectomy-induced osteoporosis in rats.
Topics: Animals; Apigenin; Biomarkers; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Cytokines; Disease Models, Animal; Female; Femur; Gene Expression Regulation; Glucosides; Humans; Inflammation Mediators; Lipids; Osteoporosis, Postmenopausal; Ovariectomy; Rats, Wistar | 2020 |
Nine absorbed components pharmacokinetic of raw and processed Moutan Cortex in normal and blood-heat and hemorrhage syndrome model rats.
Topics: Animals; Benzoates; Chromatography, High Pressure Liquid; Disease Models, Animal; Drugs, Chinese Herbal; Glucosides; Hemorrhage; Limit of Detection; Linear Models; Male; Medicine, Chinese Traditional; Paeonia; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry; Terpenes | 2020 |
Effects of empagliflozin and target-organ damage in a novel rodent model of heart failure induced by combined hypertension and diabetes.
Topics: Animals; Benzhydryl Compounds; C-Peptide; Cardiotonic Agents; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucosides; Heart Failure; Humans; Hyperinsulinism; Hypertension; Male; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Sodium-Glucose Transporter 2 Inhibitors | 2020 |
The effects of liraglutide and dapagliflozin on cardiac function and structure in a multi-hit mouse model of heart failure with preserved ejection fraction.
Topics: Angiotensin II; Animals; Benzhydryl Compounds; Blood Glucose; Diet, High-Fat; Disease Models, Animal; Female; Fibrosis; Gene Expression Regulation; Glucagon-Like Peptide-1 Receptor; Glucosides; Heart Failure, Diastolic; Hypertrophy, Left Ventricular; Incretins; Liraglutide; Mice, Inbred C57BL; Myocardium; Signal Transduction; Sodium-Glucose Transporter 2 Inhibitors; Ventricular Function, Left; Ventricular Remodeling | 2021 |
Nodakenin alleviates renal ischaemia-reperfusion injury via inhibiting reactive oxygen species-induced NLRP3 inflammasome activation.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Cells, Cultured; Coumarins; Disease Models, Animal; Drug Discovery; Glucosides; Inflammasomes; Interleukin-1beta; Kidney; Mice; Mice, Inbred C57BL; Oxidative Stress; Reactive Oxygen Species; Reperfusion Injury; Tumor Necrosis Factor-alpha | 2021 |
Cardioprotective Effects of Dietary Flaxseed Post-Infarction Are Associated with Changes in MicroRNA Expression.
Topics: alpha-Linolenic Acid; Animal Feed; Animals; Butylene Glycols; Collagen Type I; Disease Models, Animal; Fatty Acids; Flax; Glucosides; Homeodomain Proteins; Male; MicroRNAs; Myocardial Infarction; Rats, Sprague-Dawley; Seeds; Up-Regulation | 2020 |
Empagliflozin reduces the senescence of cardiac stromal cells and improves cardiac function in a murine model of diabetes.
Topics: Animals; Benzhydryl Compounds; Biopsy; Cell Survival; Cellular Senescence; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucosides; Heart; Heart Failure; Inflammation; Male; Mice; Mice, Inbred C57BL; Myocardium; Sodium-Glucose Transporter 2; Stromal Cells; Ventricular Function, Left | 2020 |
Rhodiola crenulata reduces ventricular arrhythmia through mitigating the activation of IL-17 and inhibiting the MAPK signaling pathway.
Topics: Animals; Anti-Inflammatory Agents; Arrhythmias, Cardiac; CD4 Lymphocyte Count; Chemokine CCL20; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Electrocardiography; Glucosides; Inflammation Mediators; Interleukin-17; MAP Kinase Signaling System; NLR Family, Pyrin Domain-Containing 3 Protein; Phenols; Rabbits; Rhodiola; RNA, Messenger; Signal Transduction | 2021 |
Topics: Acute Coronary Syndrome; Adolescent; Adsorption; Adult; Aged; Animals; Aspergillus; Aspergillus oryzae; Benzhydryl Compounds; Biocatalysis; Biological Availability; Biomarkers; Biomass; Brain; Brain Injuries, Traumatic; Cadmium; Calorimetry, Differential Scanning; Carbon; Carcinoma, Transitional Cell; Catalysis; Cell Death; Cells, Immobilized; Child; Child, Preschool; China; Chitosan; Creatine Kinase, MB Form; Cyclodextrins; Defibrillators, Implantable; Dendritic Spines; Diabetes Mellitus, Type 2; Diastole; Directed Molecular Evolution; Disease Models, Animal; Disease Progression; Down-Regulation; Electric Countershock; Electrolytes; Electrophoresis, Polyacrylamide Gel; Endopeptidase K; Environmental Monitoring; Esterification; Esters; Feasibility Studies; Female; Fruit; Gene Library; Glial Fibrillary Acidic Protein; Glucosides; Hippocampus; Humans; Hydrogen-Ion Concentration; Hydrolysis; Infant; Infant, Newborn; Inflammation; Ions; Kinetics; Lipase; Liver Cirrhosis; Logistic Models; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malus; Maze Learning; Melatonin; Mercury; Mice; Mice, Inbred C57BL; Middle Aged; Mining; Molecular Docking Simulation; Molecular Weight; Molybdenum; Motor Cortex; Mutagenesis, Site-Directed; Mutation; Neoplasm Recurrence, Local; Nephrectomy; Nephroureterectomy; Neurons; Oxidative Stress; Patient Discharge; Proof of Concept Study; Propionates; Prospective Studies; Protein Engineering; Protein Structure, Quaternary; Protons; PrPC Proteins; PrPSc Proteins; Rats; Rats, Wistar; Recovery of Function; Registries; Retrospective Studies; Rivers; ROC Curve; Scrapie; Sodium-Glucose Transporter 2 Inhibitors; Solubility; Solvents; Spatial Memory; Stereoisomerism; Synapses; Temperature; Time Factors; Treatment Outcome; Troponin T; Urinary Bladder Neoplasms; Urinary Tract; Ventricular Function, Left; Ventricular Remodeling; Water; Water Pollutants, Chemical; Water Purification; X-Ray Diffraction; Young Adult; Zebrafish | 2021 |
Paeoniflorin-6'-o-benzene sulfonate (CP-25) improves vasculitis through inhibiting IL-17A/JAK/STAT3 signaling pathway in endothelial cells of HFD CIA rats.
Topics: Animals; Arthritis, Rheumatoid; Diet, High-Fat; Disease Models, Animal; Endothelial Cells; Glucosides; Humans; Interleukin-17; Male; Monoterpenes; Rats; Signal Transduction; Vasculitis | 2021 |
Salidroside can target both P4HB-mediated inflammation and melanogenesis of the skin.
Topics: Adult; Animals; Cell Line, Tumor; Disease Models, Animal; Female; Glucosides; Healthy Volunteers; Humans; Hyperpigmentation; Interferon Regulatory Factor-1; Male; Melanins; Melanocytes; Mice; Molecular Docking Simulation; Monophenol Monooxygenase; Phenols; Procollagen-Proline Dioxygenase; Protein Disulfide-Isomerases; Skin; Skin Aging; Skin Cream; Skin Lightening Preparations; Skin Pigmentation; Transcriptional Activation; Ubiquitination; Ultraviolet Rays; Upstream Stimulatory Factors; Young Adult | 2020 |
Gastrodin Regulates the Notch Signaling Pathway and Sirt3 in Activated Microglia in Cerebral Hypoxic-Ischemia Neonatal Rats and in Activated BV-2 Microglia.
Topics: Animals; Animals, Newborn; Benzyl Alcohols; Carotid Artery, Common; Cells, Cultured; Cerebral Cortex; Corpus Callosum; Diamines; Disease Models, Animal; Drug Synergism; Gene Expression Regulation; Glucosides; Hypoxia-Ischemia, Brain; Ligation; Lipopolysaccharides; Microglia; Neuroinflammatory Diseases; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Notch1; Signal Transduction; Sirtuins; Thiazoles; Tumor Necrosis Factor-alpha | 2021 |
Syringin alleviates ovalbumin-induced lung inflammation in BALB/c mice asthma model via NF-κB signaling pathway.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Cytokines; Disease Models, Animal; Female; Glucosides; Inflammation; Lung; Mice; Mice, Inbred BALB C; NF-kappa B; Ovalbumin; Phenylpropionates; Pneumonia; Signal Transduction | 2021 |
Paeoniflorin accelerates foot wound healing in diabetic rats though activating the Nrf2 pathway.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Proliferation; Diabetes Mellitus, Experimental; Diabetic Foot; Diet, High-Fat; Disease Models, Animal; Gene Expression Regulation; Glucose; Glucosides; HaCaT Cells; Humans; Hypoglycemic Agents; Male; Monoterpenes; NF-E2-Related Factor 2; Rats; Rats, Sprague-Dawley; Signal Transduction; Streptozocin; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A; Wound Healing | 2020 |
Dapagliflozin suppresses ER stress and protects doxorubicin-induced cardiotoxicity in breast cancer patients.
Topics: Adolescent; Adult; Aged; Animals; Antibiotics, Antineoplastic; Apoptosis; Benzhydryl Compounds; Breast Neoplasms; Cardiotoxicity; Caspase 3; Cell Line; Cell Survival; Comorbidity; Diabetes Complications; Diabetes Mellitus, Experimental; Disease Models, Animal; Doxorubicin; Echocardiography; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Female; Glucosides; Humans; Male; Middle Aged; Myocytes, Cardiac; Protective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Retrospective Studies; Young Adult | 2021 |
Orientin relieves lipopolysaccharide-induced acute lung injury in mice: The involvement of its anti-inflammatory and anti-oxidant properties.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Flavonoids; Glucosides; Inflammasomes; Lipopolysaccharides; Lung; Male; Mice, Inbred C57BL; NF-E2-Related Factor 2; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Pneumonia; Signal Transduction | 2021 |
Inhibition of HMGB1 involved in the protective of salidroside on liver injury in diabetes mice.
Topics: Animals; Anti-Inflammatory Agents; Blood Glucose; Cell Line; Cytokines; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucosides; Hepatitis; HMGB1 Protein; Humans; Hypoglycemic Agents; Liver; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Phenols; Receptor for Advanced Glycation End Products; Signal Transduction; Toll-Like Receptor 4 | 2020 |
Gastrodin alleviates perioperative neurocognitive dysfunction of aged mice by suppressing neuroinflammation.
Topics: Animals; Anti-Inflammatory Agents; Behavior, Animal; Benzyl Alcohols; Cognition; Disease Models, Animal; Fear; Glucosides; Glycogen Synthase Kinase 3 beta; Hippocampus; Inflammation Mediators; Interleukin-10; Interleukin-1beta; Interleukin-6; Male; Maze Learning; Mice, Inbred C57BL; Microglia; Perioperative Period; Phosphorylation; Postoperative Cognitive Complications; tau Proteins; Tumor Necrosis Factor-alpha | 2021 |
Scopolin Attenuates Osteoporotic Bone Loss in Ovariectomized Mice.
Topics: 3T3 Cells; Animals; Bone Density; Cell Differentiation; Coumarins; Disease Models, Animal; Drugs, Chinese Herbal; Female; Glucosides; Mice; Osteoblasts; Osteoclasts; Osteogenesis; Osteoporosis | 2020 |
Salidroside regulates inflammatory pathway of alveolar macrophages by influencing the secretion of miRNA-146a exosomes by lung epithelial cells.
Topics: Acute Lung Injury; Animals; Coculture Techniques; Disease Models, Animal; Epithelial Cells; Exosomes; Glucosides; Inflammation; Macrophages, Alveolar; Male; MicroRNAs; Phenols; Rats; Rats, Sprague-Dawley; Signal Transduction | 2020 |
Apigenin-7-
Topics: Animals; Antioxidants; Apigenin; Apoptosis; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Glucosides; Glycogen Synthase Kinase 3 beta; Infarction, Middle Cerebral Artery; Male; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Phosphatidylinositol 3-Kinase; Phosphorylation; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction | 2020 |
Dapagliflozin Does Not Modulate Atherosclerosis in Mice with Insulin Resistance.
Topics: Animals; Atherosclerosis; Benzhydryl Compounds; Blood Glucose; Computational Biology; Disease Models, Animal; Fasting; Glucose; Glucosides; Immunohistochemistry; Insulin Resistance; Macrophages; Mice; Mice, Knockout, ApoE; Plaque, Atherosclerotic; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2020 |
Salidroside simultaneously reduces de novo lipogenesis and cholesterol biosynthesis to attenuate atherosclerosis in mice.
Topics: 3-Hydroxybutyric Acid; Animals; Anticholesteremic Agents; Atherosclerosis; Cholesterol; Diet, High-Fat; Disease Models, Animal; Fatty Acids; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Glucose; Glucosides; Glycogen; Hypercholesterolemia; Lipidomics; Lipogenesis; Liver; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Phenols; Proton Magnetic Resonance Spectroscopy | 2021 |
Paeoniflorin elicits the anti-proliferative effects on glioma cell via targeting translocator protein 18 KDa.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Glioma; Glucosides; Isoquinolines; Monoterpenes; Neurosteroids; Phytotherapy; Receptors, GABA | 2021 |
Optimal combination of anti-inflammatory components from Chinese medicinal formula Liang-Ge-San.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Drugs, Chinese Herbal; Emodin; Flavanones; Flavonoids; Glucosides; Inflammation; Interleukin-6; Larva; Lipopolysaccharides; Macrophages; MAP Kinase Signaling System; Medicine, Chinese Traditional; Myeloid Differentiation Factor 88; Neutrophil Infiltration; Neutrophils; NF-kappa B; Tumor Necrosis Factor-alpha; Yolk Sac; Zebrafish; Zebrafish Proteins | 2021 |
Gastrodin alleviates seizure severity and neuronal excitotoxicities in the rat lithium-pilocarpine model of temporal lobe epilepsy via enhancing GABAergic transmission.
Topics: Animals; Anticonvulsants; Benzyl Alcohols; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Gastrodia; Glucosides; Hippocampus; Lithium; Male; Medicine, Chinese Traditional; Neurons; Neuroprotective Agents; Pilocarpine; Rats, Sprague-Dawley; Receptors, GABA-A; Rhizome; Seizures; Status Epilepticus | 2021 |
Paeoniflorin Alleviates Abnormalities in Rats with Functional Dyspepsia by Stimulating the Release of Acetylcholine.
Topics: Acetylcholine; Animals; Clonidine; Disease Models, Animal; Dyspepsia; Glucosides; Iodoacetamide; Male; Monoterpenes; Rats; Rats, Sprague-Dawley | 2020 |
Effect of Empagliflozin and Liraglutide on the Nucleotide-Binding and Oligomerization Domain-Like Receptor Family Pyrin Domain-Containing 3 Inflammasome in a Rodent Model of Type 2 Diabetes Mellitus.
Topics: Animals; Benzhydryl Compounds; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Glucagon-Like Peptide-1 Receptor; Glucosides; Inflammasomes; Liraglutide; Male; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Sodium-Glucose Transporter 2 Inhibitors | 2021 |
Spinal mechanisms contributing to the development of pain hypersensitivity induced by sphingolipids in the rat.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Flavanones; Flavonoids; Glucosides; Hyperalgesia; Isoflavones; Male; Rats; Rats, Wistar; Sphingolipids; Sphingosine; Spinal Cord | 2021 |
Reduning injection and its effective constituent luteoloside protect against sepsis partly via inhibition of HMGB1/TLR4/NF-κB/MAPKs signaling pathways.
Topics: Animals; Anti-Infective Agents, Local; Cecum; Disease Models, Animal; Drugs, Chinese Herbal; Glucosides; HMGB1 Protein; Injections; Lipopolysaccharides; Luteolin; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Myeloid Differentiation Factor 88; NF-kappa B p50 Subunit; Nitric Oxide; Protective Agents; RAW 264.7 Cells; Sepsis; Signal Transduction; Toll-Like Receptor 4 | 2021 |
Salidroside protects against cardiomyocyte apoptosis and ventricular remodeling by AKT/HO-1 signaling pathways in a diabetic cardiomyopathy mouse model.
Topics: Animals; Apoptosis; Diabetic Cardiomyopathies; Disease Models, Animal; Dose-Response Relationship, Drug; Glucosides; Heme Oxygenase-1; Male; Mice; Myocytes, Cardiac; Phenols; Proto-Oncogene Proteins c-akt; Signal Transduction; Ventricular Remodeling | 2021 |
Glomerular hyperfiltration with hyperglycemia in the spontaneously diabetic Torii (SDT) fatty rat, an obese type 2 diabetic model.
Topics: Animals; Benzhydryl Compounds; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Glomerular Filtration Rate; Glucosides; Hyperglycemia; Male; Obesity; Rats; Rats, Sprague-Dawley; Sodium-Glucose Transporter 2 Inhibitors | 2021 |
Effects of Sodium-Glucose Cotransporter 2 Inhibition on Glucose Metabolism, Liver Function, Ascites, and Hemodynamics in a Mouse Model of Nonalcoholic Steatohepatitis and Type 2 Diabetes.
Topics: Animals; Ascites; Benzhydryl Compounds; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Diuresis; Drug Therapy, Combination; Furosemide; Glucosides; Hemodynamics; Liver; Male; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors | 2020 |
Metabolic cardio- and reno-protective effects of empagliflozin in a prediabetic rat model.
Topics: Animals; Benzhydryl Compounds; Disease Models, Animal; Glucose; Glucosides; Heart; Insulin Resistance; Ketone Bodies; Kidney; Male; Oxidative Stress; Prediabetic State; Protective Agents; Rats; Rats, Wistar | 2020 |
Empagliflozin and Liraglutide Differentially Modulate Cardiac Metabolism in Diabetic Cardiomyopathy in Rats.
Topics: Animals; Apoptosis; Benzhydryl Compounds; Biomarkers; Cytokines; Diabetic Cardiomyopathies; Disease Models, Animal; Echocardiography; Energy Metabolism; Fatty Acids; Fibrosis; Glucose; Glucosides; Heart Function Tests; Hypoglycemic Agents; Immunohistochemistry; Inflammation Mediators; Liraglutide; Myocardium; Rats; Sodium-Glucose Transporter 2 Inhibitors | 2021 |
Isoliquiritin exert protective effect on telencephalon infarction injury by regulating multi-pathways in zebrafish model of ischemic stroke.
Topics: Animals; Antioxidants; Apoptosis; Brain Ischemia; Chalcone; Disease Models, Animal; Enzymes; Female; Glucosides; Ischemic Stroke; Male; Oxidative Stress; Protective Agents; Signal Transduction; Telencephalon; Zebrafish; Zebrafish Proteins | 2021 |
Gastrodin - A potential drug used for the treatment of Tourette Syndrome.
Topics: Animals; Benzyl Alcohols; Brain; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Gastrodia; Glucosides; Male; Molecular Imaging; Phytotherapy; Positron-Emission Tomography; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tourette Syndrome | 2021 |
Pharmacokinetic-pharmacodynamic modeling analysis and anti-inflammatory effect of Wangbi capsule in the treatment of adjuvant-induced arthritis.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Benzopyrans; Bridged-Ring Compounds; Disease Models, Animal; Drugs, Chinese Herbal; Flavonoids; Freund's Adjuvant; Glucosides; Joints; Male; Medicine, Chinese Traditional; Monoterpenes; Rats; Rats, Sprague-Dawley | 2021 |
SIRT1 attenuates sepsis-induced acute kidney injury via Beclin1 deacetylation-mediated autophagy activation.
Topics: Acetylation; Acute Kidney Injury; Animals; Autophagy; Beclin-1; Cell Line; Disease Models, Animal; Enzyme Activation; Enzyme Activators; Glucosides; Humans; Kidney Tubules, Proximal; Male; Mice, Inbred C57BL; Resveratrol; Sepsis; Signal Transduction; Sirtuin 1; Stilbenes; Time Factors | 2021 |
Paeoniflorin attenuates DHEA-induced polycystic ovary syndrome via inactivation of TGF-β1/Smads signaling pathway
Topics: Animals; Dehydroepiandrosterone; Disease Models, Animal; Estrous Cycle; Female; Glucosides; Monoterpenes; Ovary; Polycystic Ovary Syndrome; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad Proteins; Transforming Growth Factor beta1 | 2021 |
Glucosyl Hesperidin Has an Anti-diabetic Effect in High-Fat Diet-Induced Obese Mice.
Topics: 3T3-L1 Cells; Adipose Tissue; Animals; Chemokine CCL2; Coculture Techniques; Diet, High-Fat; Disease Models, Animal; Glucosides; Hesperidin; Hyperglycemia; Hypoglycemic Agents; Macrophages; Male; Mice; Mice, Inbred C57BL; Obesity; RAW 264.7 Cells | 2021 |
Gastrodin attenuates lithium-pilocarpine-induced epilepsy by activating AMPK-mediated PPARα in a juvenile rat model.
Topics: Adenylate Kinase; Animals; Behavior, Animal; Benzyl Alcohols; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Electroencephalography; Enzyme Activation; Epilepsy; Glucosides; Lithium Compounds; Nerve Growth Factor; Pilocarpine; PPAR alpha; Rats; Rats, Sprague-Dawley; Signal Transduction | 2021 |
Enhanced effects of salidroside on erectile function and corpora cavernosa autophagy in a cavernous nerve injury rat model.
Topics: Animals; Autophagy; Disease Models, Animal; Erectile Dysfunction; Glucosides; Humans; Male; Penile Erection; Penis; Phenols; Rats; Rats, Sprague-Dawley | 2021 |
Direct Cardiac Actions of the Sodium Glucose Co-Transporter 2 Inhibitor Empagliflozin Improve Myocardial Oxidative Phosphorylation and Attenuate Pressure-Overload Heart Failure.
Topics: Animals; Benzhydryl Compounds; Blood Pressure; Disease Models, Animal; Echocardiography; Glucosides; Heart Failure; Heart Ventricles; Male; Mice; Mice, Inbred C57BL; Myocardium; Oxidative Phosphorylation; Sodium-Glucose Transporter 2 Inhibitors; Stroke Volume; Ventricular Function, Left | 2021 |
Dapagliflozin reverses the imbalance of T helper 17 and T regulatory cells by inhibiting SGK1 in a mouse model of diabetic kidney disease.
Topics: Animals; Benzhydryl Compounds; China; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Glucosides; Immediate-Early Proteins; Male; Mice; Mice, Inbred C57BL; Protein Serine-Threonine Kinases; T-Lymphocytes, Regulatory; Th17 Cells | 2021 |
Semen Cuscutae-Fructus Lycii improves spermatogenic dysfunction by repairing the blood-testis barrier in rats according to in silico and in vitro methods.
Topics: Animals; beta Catenin; Blood-Testis Barrier; Cadherins; Computer Simulation; Connexin 43; Disease Models, Animal; Drugs, Chinese Herbal; Gene Expression Regulation; Genes, jun; Glucosides; In Vitro Techniques; Infertility, Male; Male; Nerve Tissue Proteins; Occludin; p38 Mitogen-Activated Protein Kinases; Protein Interaction Maps; Rats, Sprague-Dawley; Sperm Count; Sperm Motility; Spermatogenesis; Testis; Tripterygium; Zonula Occludens-1 Protein | 2021 |
Dapagliflozin Improves Cardiac Hemodynamics and Mitigates Arrhythmogenesis in Mitral Regurgitation-Induced Myocardial Dysfunction.
Topics: Animals; Arrhythmias, Cardiac; Benzhydryl Compounds; Disease Models, Animal; Glucosides; Hemodynamics; Male; Mitral Valve Insufficiency; Rats; Rats, Sprague-Dawley; Sodium-Glucose Transporter 2 Inhibitors | 2021 |
Verbascoside-enriched fraction from Buddleja cordata Kunth ameliorates the effects of diabetic embryopathy in an animal model.
Topics: Animals; Buddleja; Diabetes Mellitus; Disease Models, Animal; Fetal Diseases; Glucosides; Phenols; Pregnancy; Rats | 2021 |
Paeoniflorin modulates oxidative stress, inflammation and hepatic stellate cells activation to alleviate CCl4-induced hepatic fibrosis by upregulation of heme oxygenase-1 in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbon Tetrachloride; Cytokines; Disease Models, Animal; Glucosides; Heme Oxygenase-1; Hepatic Stellate Cells; Inflammation; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Monoterpenes; Oxidative Stress; Up-Regulation | 2021 |
Impact of SGLT-2 Inhibition on Cardiometabolic Abnormalities in a Rat Model of Polycystic Ovary Syndrome.
Topics: Animals; Benzhydryl Compounds; Dihydrotestosterone; Disease Models, Animal; Female; Glucosides; Heart; Hyperandrogenism; Polycystic Ovary Syndrome; Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2021 |
Polydatin alleviates traumatic brain injury: Role of inhibiting ferroptosis.
Topics: Animals; Brain; Brain Injuries, Traumatic; Cell Line; Cell Survival; Disease Models, Animal; Ferroptosis; Glucosides; Hemin; Iron; Male; Mice; Mice, Inbred C57BL; Neurons; Neuroprotection; Neuroprotective Agents; Phospholipid Hydroperoxide Glutathione Peroxidase; Stilbenes | 2021 |
CP-25 ameliorates methotrexate induced nephrotoxicity via improving renal apoptosis and methotrexate excretion.
Topics: Acute Kidney Injury; Animals; Apoptosis; Disease Models, Animal; Gene Expression; Glucosides; Kidney; Male; Methotrexate; Molecular Targeted Therapy; Monoterpenes; Organic Anion Transporters, Sodium-Independent; Rats, Sprague-Dawley | 2021 |
Wogonoside attenuates the articular cartilage injury and the infiltration of Th1/Th2-type cytokines in papain-induced osteoarthritis in rat model via inhibiting the NF-κB and ERK1/2 activation.
Topics: Animals; Cartilage, Articular; Cytokines; Disease Models, Animal; Flavanones; Glucosides; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Osteoarthritis; Papain; Rats; Rats, Sprague-Dawley; Th1 Cells; Th2 Cells | 2021 |
Paeoniflorin protects against dextran sulfate sodium (DSS)-induced colitis in mice through inhibition of inflammation and eosinophil infiltration.
Topics: Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Eosinophils; Female; Glucosides; Humans; Intestinal Mucosa; Mice; Monoterpenes; Paeonia; Signal Transduction | 2021 |
Protective effects of liquiritin on UVB-induced skin damage in SD rats.
Topics: Animals; Collagen; Disease Models, Animal; Flavanones; Glucosides; Humans; NF-kappa B; Oxidative Stress; Photosensitivity Disorders; Proteolysis; Rats; Reactive Oxygen Species; Signal Transduction; Sirtuins; Skin; Skin Neoplasms; Ultraviolet Rays | 2021 |
Inhibition of the transient receptor potential vanilloid 3 channel attenuates carbon tetrachloride-induced hepatic fibrosis.
Topics: Animals; Caffeic Acids; Carbon Tetrachloride; Cells, Cultured; Disease Models, Animal; Gene Knockdown Techniques; Glucosides; Hepatic Stellate Cells; Humans; Immunohistochemistry; Liver Cirrhosis; Liver Cirrhosis, Experimental; Male; Mice; Mice, Inbred C57BL; Phenylacetates; RNA, Messenger; RNA, Small Interfering; TRPV Cation Channels; Up-Regulation | 2021 |
Empagliflozin ameliorates symptoms of diabetes and renal tubular dysfunction in a rat model of diabetes with enlarged kidney (DEK).
Topics: Animals; Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucosides; Hyperglycemia; Kidney; Kidney Diseases; Male; Rats; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2021 |
Paeoniflorin attenuates the allergic contact dermatitis response via inhibiting the IFN-γ production and the NF-κB/IκBα signaling pathway in T lymphocytes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Dermatitis, Allergic Contact; Disease Models, Animal; Glucosides; Humans; Inflammation; Interferon-gamma; Monoterpenes; NF-kappa B; NF-KappaB Inhibitor alpha; Signal Transduction; T-Lymphocytes | 2021 |
Synergistic cardioptotection by tilianin and syringin in diabetic cardiomyopathy involves interaction of TLR4/NF-κB/NLRP3 and PGC1a/SIRT3 pathways.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Disease Models, Animal; Drug Synergism; Flavonoids; Glucosides; Glycosides; Inflammasomes; Male; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phenylpropionates; Rats; Rats, Sprague-Dawley; Signal Transduction; Sirtuins; Toll-Like Receptor 4 | 2021 |
Paeoniflorin ameliorates ischemic injury in rat brain via inhibiting cytochrome c/caspase3/HDAC4 pathway.
Topics: Animals; Anti-Inflammatory Agents; Brain Ischemia; Caspase 3; Cytochromes c; Disease Models, Animal; Glucosides; Histone Deacetylases; Male; Monoterpenes; Morris Water Maze Test; Open Field Test; Rats; Rats, Sprague-Dawley; Rotarod Performance Test; Signal Transduction | 2022 |
The sodium-glucose cotransporter-2 inhibitor Tofogliflozin prevents the progression of nonalcoholic steatohepatitis-associated liver tumors in a novel murine model.
Topics: Animals; Benzhydryl Compounds; Blood Glucose; Cellular Senescence; Diabetes Mellitus, Experimental; Diet, Western; Disease Models, Animal; Disease Progression; Glucosides; Hepatocytes; Insulin; Liver; Liver Neoplasms; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Obesity; Receptor, Melanocortin, Type 4; Sodium-Glucose Transporter 2 Inhibitors | 2021 |
Total glucosides of Paeony restores intestinal barrier function through inhibiting Lyn/Snail signaling pathway in colitis mice.
Topics: Animals; Caco-2 Cells; Colitis; Dextran Sulfate; Disease Models, Animal; Glucosides; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Male; Mice, Inbred C57BL; Monoterpenes; Paeonia; Permeability; Snail Family Transcription Factors; src-Family Kinases; Tight Junction Proteins; Tight Junctions | 2021 |
Corilagin ameliorates atherosclerosis by regulating MMP-1, -2, and -9 expression in vitro and in vivo.
Topics: Animals; Atherosclerosis; Carotid Artery, Common; Diet, High-Fat; Disease Models, Animal; Glucosides; Humans; Hydrolyzable Tannins; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; RAW 264.7 Cells; Swine; Swine, Miniature | 2021 |
Total Glucosides of Paeony Inhibited Autophagy and Improved Acute Kidney Injury Induced by Ischemia-Reperfusion via the lncRNA TUG1/miR-29a/PTEN Axis.
Topics: Acute Kidney Injury; Administration, Oral; Animals; Autophagy; Cells, Cultured; Disease Models, Animal; Glucosides; Male; MicroRNAs; Paeonia; PTEN Phosphohydrolase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Long Noncoding | 2021 |
Empagliflozin Significantly Prevents the Doxorubicin-induced Acute Cardiotoxicity via Non-antioxidant Pathways.
Topics: Action Potentials; Animals; Benzhydryl Compounds; Cardiotoxicity; Cell Proliferation; Disease Models, Animal; Doxorubicin; Glucosides; Heart Diseases; Heart Rate; Male; Mitochondria, Heart; Myocytes, Cardiac; Rats, Sprague-Dawley; Sodium-Glucose Transporter 2 Inhibitors; Stroke Volume; Ventricular Function, Left | 2021 |
Gastrodin alleviates inflammatory injury of cardiomyocytes in septic shock mice via inhibiting NLRP3 expression.
Topics: Animals; Benzyl Alcohols; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Glucosides; Inflammation; Interleukin-1beta; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; NLR Family, Pyrin Domain-Containing 3 Protein; Shock, Septic | 2021 |
Effects of Finerenone Combined with Empagliflozin in a Model of Hypertension-Induced End-Organ Damage.
Topics: Animals; Benzhydryl Compounds; Disease Models, Animal; Drug Combinations; Female; Glucosides; Heart Diseases; Hypertension; Kidney Diseases; Naphthyridines; Rats; Sodium-Glucose Transporter 2 Inhibitors | 2021 |
Dapagliflozin: a sodium-glucose cotransporter 2 inhibitor, attenuates angiotensin II-induced cardiac fibrotic remodeling by regulating TGFβ1/Smad signaling.
Topics: Angiotensin II; Animals; Antifibrotic Agents; Benzhydryl Compounds; Cells, Cultured; Disease Models, Animal; Fibroblasts; Fibrosis; Glucosides; Hypertrophy, Left Ventricular; Male; Myocardium; Rats, Sprague-Dawley; Signal Transduction; Smad Proteins; Sodium-Glucose Transporter 2 Inhibitors; Transforming Growth Factor beta1; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2021 |
Polydatin alleviates severe traumatic brain injury induced acute lung injury by inhibiting S100B mediated NETs formation.
Topics: Acute Lung Injury; Animals; Brain Injuries, Traumatic; Disease Models, Animal; Extracellular Traps; Glucosides; Humans; Lung; Male; Oxidative Stress; Rats; S100 Calcium Binding Protein beta Subunit; Stilbenes | 2021 |
Gastrodia remodels intestinal microflora to suppress inflammation in mice with early atherosclerosis.
Topics: Acetic Acid; Animals; Aorta; Atherosclerosis; Benzyl Alcohols; Butyric Acid; Disease Models, Animal; Drugs, Chinese Herbal; Fatty Acids, Volatile; Gastrodia; Gastrointestinal Microbiome; Glucosides; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-1beta; Intestinal Mucosa; Lipids; Mice, Inbred C57BL; Propionates; Tight Junction Proteins; Tumor Necrosis Factor-alpha | 2021 |
Dapagliflozin alleviates cardiac fibrosis through suppressing EndMT and fibroblast activation via AMPKα/TGF-β/Smad signalling in type 2 diabetic rats.
Topics: AMP-Activated Protein Kinases; Animals; Benzhydryl Compounds; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Diet, High-Fat; Disease Models, Animal; Epithelial-Mesenchymal Transition; Fibroblasts; Fibrosis; Glucosides; Male; Mesoderm; Rats; Signal Transduction; Smad4 Protein; Sodium-Glucose Transporter 2 Inhibitors; Transforming Growth Factor beta | 2021 |
Inhibitory effect of paeoniflorin on IgE-dependent and IgE-independent mast cell degranulation in vitro and vivo.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Degranulation; Disease Models, Animal; Glucosides; Immunoglobulin E; Mast Cells; Mice; Monoterpenes; Plant Extracts | 2021 |
Characteristics of Ventricular Electrophysiological Substrates in Metabolic Mice Treated with Empagliflozin.
Topics: Animals; Benzhydryl Compounds; Cardiovascular Diseases; Connexin 43; Connexins; Diet, High-Fat; Disease Models, Animal; Echocardiography; Electrocardiography; Gene Expression Regulation; Glucose; Glucosides; Glyburide; Humans; Metabolic Syndrome; Mice; Sodium-Glucose Transporter 2 | 2021 |
Empagliflozin Improves Metabolic and Hepatic Outcomes in a Non-Diabetic Obese Biopsy-Proven Mouse Model of Advanced NASH.
Topics: Animals; Antigens, CD; Benzhydryl Compounds; Biopsy; Body Composition; Body Weight; Disease Models, Animal; Glucose; Glucosides; Homeostasis; Insulin Resistance; Lactosylceramides; Lipidomics; Liver; Mice, Inbred C57BL; Mice, Obese; Non-alcoholic Fatty Liver Disease; Triglycerides | 2021 |
The impact of empagliflozin on cardiac physiology and fibrosis early after myocardial infarction in non-diabetic rats.
Topics: Animals; Benzhydryl Compounds; Collagen; Disease Models, Animal; Fibrosis; Glucosides; Hydroxyproline; Male; Myocardial Infarction; Myocardium; Rats, Sprague-Dawley; Smad3 Protein; Sodium-Glucose Transporter 2 Inhibitors; Stroke Volume; Time Factors; Transforming Growth Factor beta1; Ventricular Function, Left | 2021 |
Gastrodin extends the lifespan and protects against neurodegeneration in the Drosophila PINK1 model of Parkinson's disease.
Topics: Animals; Benzyl Alcohols; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Drugs, Chinese Herbal; Female; Gastrodia; Glucosides; Humans; Longevity; Male; Neuroprotection; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Protein Serine-Threonine Kinases | 2021 |
Salidroside Activates the AMP-Activated Protein Kinase Pathway to Suppress Nonalcoholic Steatohepatitis in Mice.
Topics: AMP-Activated Protein Kinases; Animals; Cells, Cultured; Diet, High-Fat; Disease Models, Animal; Glucosides; Hepatocytes; Humans; Liver; Male; Mice; Non-alcoholic Fatty Liver Disease; Phenols; Primary Cell Culture; Signal Transduction | 2021 |
Gastrodin Improves Nonalcoholic Fatty Liver Disease Through Activation of the Adenosine Monophosphate-Activated Protein Kinase Signaling Pathway.
Topics: AMP-Activated Protein Kinases; Animals; Benzyl Alcohols; Diet, High-Fat; Disease Models, Animal; Glucosides; Humans; Lipid Metabolism; Male; Mice; Non-alcoholic Fatty Liver Disease; Signal Transduction | 2021 |
The SGLT-2 inhibitor empagliflozin improves myocardial strain, reduces cardiac fibrosis and pro-inflammatory cytokines in non-diabetic mice treated with doxorubicin.
Topics: Animals; Anti-Inflammatory Agents; Antifibrotic Agents; Apoptosis; Benzhydryl Compounds; Cardiotoxicity; Cell Line; Cytokines; Disease Models, Animal; Doxorubicin; Female; Ferroptosis; Fibrosis; Glucosides; Heart Diseases; Inflammasomes; Inflammation Mediators; Mice, Inbred C57BL; Myeloid Differentiation Factor 88; Myocytes, Cardiac; NLR Family, Pyrin Domain-Containing 3 Protein; Signal Transduction; Sodium-Glucose Transporter 2 Inhibitors; Ventricular Function, Left | 2021 |
Polydatin attenuates hepatic stellate cell proliferation and liver fibrosis by suppressing sphingosine kinase 1.
Topics: Animals; Apoptosis; Biomarkers; Cell Line, Transformed; Cell Proliferation; Disease Models, Animal; Enzyme Inhibitors; Glucosides; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Mice; Phosphotransferases (Alcohol Group Acceptor); Signal Transduction; Stilbenes | 2020 |
Polydatin gold nanoparticles potentiate antitumor effect of doxorubicin in Ehrlich ascites carcinoma-bearing mice.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Disease Models, Animal; Doxorubicin; Drug Synergism; Drugs, Chinese Herbal; Fallopia japonica; Female; Glucosides; Gold; Heart; Metal Nanoparticles; Mice; Nanoparticle Drug Delivery System; Phytochemicals; Phytotherapy; Protective Agents; Stilbenes; Treatment Outcome; Tumor Burden | 2021 |
Acteoside isolated from Colebrookea oppositifolia attenuates I/R brain injury in Wistar rats via modulation of HIF-1α, NF-κB, and VEGF pathways.
Topics: Animals; Antioxidants; Disease Models, Animal; Dose-Response Relationship, Drug; Glucosides; Hypoxia-Inducible Factor 1, alpha Subunit; Lamiaceae; Male; NF-kappa B; Phenols; Plant Extracts; Rats; Rats, Wistar; Reperfusion Injury; Stroke; Vascular Endothelial Growth Factor A | 2021 |
Early combination therapy of empagliflozin and linagliptin exerts beneficial effects on pancreatic β cells in diabetic db/db mice.
Topics: Animals; Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Drug Combinations; Glucosides; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Linagliptin; Male; Mice; Mice, Inbred NOD; Mice, Inbred Strains; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2021 |
Orcinol glucoside improves the depressive-like behaviors of perimenopausal depression mice through modulating activity of hypothalamic-pituitary-adrenal/ovary axis and activating BDNF- TrkB-CREB signaling pathway.
Topics: Animals; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Female; Glucosides; Hippocampus; Hypothalamo-Hypophyseal System; Mice; Ovary; Perimenopause; Pituitary-Adrenal System; Rats; Resorcinols; Signal Transduction; Stress, Psychological | 2021 |
The neuroprotective effect of phillyrin in intracerebral hemorrhagic mice is produced by activation of the Nrf2 signaling pathway.
Topics: Animals; Apoptosis; Cerebral Hemorrhage; Disease Models, Animal; Glucosides; Humans; Imidazolidines; Male; Mice; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Spiro Compounds | 2021 |
Paeoniflorin ameliorates cognitive dysfunction via regulating SOCS2/IRS-1 pathway in diabetic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Cognition Disorders; Cytokines; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Glucosides; Hippocampus; Insulin Receptor Substrate Proteins; Male; Maze Learning; Monoterpenes; Phosphorylation; Random Allocation; Rats; Rats, Sprague-Dawley; Signal Transduction; Suppressor of Cytokine Signaling Proteins; tau Proteins | 2017 |
Paeoniflorin attenuates the neuroinflammatory response in a rat model of chronic constriction injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Glial Fibrillary Acidic Protein; Glucosides; Interleukin-1beta; Male; Microglia; Monoterpenes; Neuralgia; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Paeonia; Pain Threshold; Phosphorylation; Rats; Rats, Wistar; Sciatic Nerve; Spinal Cord; Tumor Necrosis Factor-alpha | 2017 |
Sodium glucose transporter-2 inhibition has no renoprotective effects on non-diabetic chronic kidney disease.
Topics: Animals; Benzhydryl Compounds; Blood Urea Nitrogen; Disease Models, Animal; Glomerular Filtration Rate; Glucosides; Hepatitis A Virus Cellular Receptor 1; Kidney; Mice; Mice, Inbred C57BL; Oxalic Acid; Protective Agents; Renal Insufficiency, Chronic; Sodium-Glucose Transporter 2 Inhibitors; Tissue Inhibitor of Metalloproteinase-2 | 2017 |
Polydatin impairs mitochondria fitness and ameliorates podocyte injury by suppressing Drp1 expression.
Topics: Animals; Apoptosis; Blood Glucose; Cell Line; Cytoprotection; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Down-Regulation; Dynamins; Glucosides; Mice, Inbred C57BL; Mitochondria; Mitochondrial Dynamics; Podocytes; Reactive Oxygen Species; RNA Interference; Signal Transduction; Stilbenes; Transfection | 2017 |
Gastrodin protects against LPS-induced acute lung injury by activating Nrf2 signaling pathway.
Topics: Acute Lung Injury; Animals; Benzyl Alcohols; Biomarkers; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Glucosides; Heme Oxygenase-1; Inflammation Mediators; Lipopolysaccharides; Mice; NF-E2-Related Factor 2; NF-kappa B; Peroxidase; Protective Agents; Respiratory Function Tests; Signal Transduction | 2017 |
Effect of empagliflozin on cardiac biomarkers in a zebrafish model of heart failure: clues to the EMPA-REG OUTCOME trial?
Topics: Animals; Animals, Genetically Modified; Aristolochic Acids; Benzhydryl Compounds; Biomarkers; Clinical Trials as Topic; Disease Models, Animal; Female; Glucosides; Heart Failure; Humans; Male; Zebrafish | 2017 |
Dietary cyanidin 3-glucoside from purple corn ameliorates doxorubicin-induced cardiotoxicity in mice.
Topics: Animal Feed; Animals; Anthocyanins; Cardiotoxicity; Cell Survival; Cytoprotection; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Female; Gene Expression Regulation; Glucosides; Heart Diseases; HeLa Cells; Humans; MCF-7 Cells; Mice, Inbred C57BL; Myocytes, Cardiac; Phytotherapy; Plant Extracts; Plants, Medicinal; Protective Agents; Time Factors; Zea mays | 2017 |
SGLT-2 Inhibition with Dapagliflozin Reduces the Activation of the Nlrp3/ASC Inflammasome and Attenuates the Development of Diabetic Cardiomyopathy in Mice with Type 2 Diabetes. Further Augmentation of the Effects with Saxagliptin, a DPP4 Inhibitor.
Topics: Adamantane; AMP-Activated Protein Kinases; Animals; Apoptosis; Benzhydryl Compounds; CARD Signaling Adaptor Proteins; Cells, Cultured; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Dipeptides; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Drug Therapy, Combination; Fibroblasts; Fibrosis; Glucosides; Hypoglycemic Agents; Inflammasomes; Inflammation Mediators; Kidney Tubules, Proximal; Male; Mice, Inbred C57BL; Mice, Obese; Myocytes, Cardiac; NLR Family, Pyrin Domain-Containing 3 Protein; Signal Transduction; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Stroke Volume; Time Factors; Ventricular Function, Left | 2017 |
Paeoniflorin suppressed IL-22 via p38 MAPK pathway and exerts anti-psoriatic effect.
Topics: Animals; Blotting, Western; Cell Line; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Glucosides; Guinea Pigs; Humans; Interleukin-22; Interleukins; Lipopolysaccharides; Male; Monoterpenes; p38 Mitogen-Activated Protein Kinases; Paeonia; Phosphorylation; Propranolol; Psoriasis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2017 |
Anti-inflammatory effects of rosmarinic acid-4-O-β-D-glucoside in reducing acute lung injury in mice infected with influenza virus.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Cinnamates; Cytokines; Depsides; Disease Models, Animal; Glucosides; Lung; Mice; Orthomyxoviridae Infections; Rosmarinic Acid; Survival Analysis; Viral Load | 2017 |
Scopolin ameliorates high-fat diet induced hepatic steatosis in mice: potential involvement of SIRT1-mediated signaling cascades in the liver.
Topics: Animals; Chromatography, High Pressure Liquid; Coumarins; Diet, High-Fat; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Fatty Liver; Glucosides; Lipid Metabolism; Lipogenesis; Magnetic Resonance Spectroscopy; Mice; Signal Transduction; Sirtuin 1 | 2017 |
Antidepressant-like effects of tetrahydroxystilbene glucoside in mice: Involvement of BDNF signaling cascade in the hippocampus.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Chronic Disease; Depressive Disorder; Disease Models, Animal; Dominance-Subordination; Glucosides; Hippocampus; Male; Mice, Inbred C57BL; Motor Activity; Neurogenesis; Receptor, trkB; Serotonin; Signal Transduction; Stilbenes; Stress, Psychological | 2017 |
Pterostilbene 4'-
Topics: Animals; Colitis; Disease Models, Animal; Glucosides; Male; Mice; Mice, Knockout; Stilbenes; Tristetraprolin | 2017 |
Polydatin alleviated radiation-induced lung injury through activation of Sirt3 and inhibition of epithelial-mesenchymal transition.
Topics: Acute Lung Injury; Animals; Cell Line; Disease Models, Animal; Epithelial Cells; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation; Glucosides; Humans; Lung; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Radiation Pneumonitis; Radiation-Protective Agents; Signal Transduction; Sirtuin 3; Smad3 Protein; Stilbenes; Th1-Th2 Balance; Transforming Growth Factor beta1 | 2017 |
Effects of a co-micronized composite containing palmitoylethanolamide and polydatin in an experimental model of benign prostatic hyperplasia.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Amides; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Dihydrotestosterone; Dinoprostone; Disease Models, Animal; Drug Combinations; Drug Compounding; Ethanolamines; Glucosides; Inflammation Mediators; Male; Oxidative Stress; Palmitic Acids; Prostate; Prostatic Hyperplasia; Rats, Sprague-Dawley; Signal Transduction; Stilbenes; Testosterone Propionate | 2017 |
Empagliflozin Improves Left Ventricular Diastolic Dysfunction in a Genetic Model of Type 2 Diabetes.
Topics: Animals; Benzhydryl Compounds; Blood Glucose; Calcium-Binding Proteins; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucosides; Hypoglycemic Agents; Male; Mice; Models, Genetic; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Signal Transduction; Ventricular Dysfunction, Left | 2017 |
Orientin Attenuates Cerebral Ischemia/Reperfusion Injury in Rat Model through the AQP-4 and TLR4/NF-κB/TNF-α Signaling Pathway.
Topics: Animals; Aquaporin 4; Brain; Brain Edema; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Flavonoids; Glucosides; Male; Neuroprotective Agents; NF-kappa B; Oxidative Stress; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2017 |
Luteoloside prevents lipopolysaccharide-induced osteolysis and suppresses RANKL-induced osteoclastogenesis through attenuating RANKL signaling cascades.
Topics: Animals; Anti-Inflammatory Agents; Calcium Signaling; Disease Models, Animal; Dose-Response Relationship, Drug; Durapatite; Glucosides; Lipopolysaccharides; Luteolin; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-kappa B; NFATC Transcription Factors; Osteoclasts; Osteogenesis; Osteolysis; RANK Ligand; RAW 264.7 Cells; Skull; Time Factors | 2018 |
Effects of an Enriched Extract of Paeoniflorin, a Monoterpene Glycoside used in Chinese Herbal Medicine, on Cholesterol Metabolism in a Hyperlipidemic Rat Model.
Topics: Animals; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Diet, High-Fat; Disease Models, Animal; Drugs, Chinese Herbal; Fatty Liver; Glucosides; Glycosides; Hyperlipidemias; Lipid Metabolism; Lipoproteins, LDL; Liver; Male; Monoterpenes; NF-E2-Related Factor 2; PPAR alpha; Rats; Rats, Sprague-Dawley; Triglycerides | 2017 |
Comparative effects of traditional Chinese and Western migraine medicines in an animal model of nociceptive trigeminovascular activation.
Topics: Animals; Benzyl Alcohols; Disease Models, Animal; Dura Mater; Glucosides; Levetiracetam; Male; Medicine, Chinese Traditional; Migraine Disorders; Neurons, Afferent; Nociceptive Pain; Pain Management; Propranolol; Pyrazines; Rats, Sprague-Dawley; Trigeminal Nerve | 2018 |
Protective role of liriodendrin in mice with dextran sulphate sodium-induced ulcerative colitis.
Topics: Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Cytokines; Dextran Sulfate; Disease Models, Animal; Disease Progression; Furans; Glucosides; Humans; Inflammation Mediators; Lipopolysaccharides; Macrophages; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred BALB C; Peroxidase; RAW 264.7 Cells | 2017 |
Total glucosides of paeony ameliorates TNBS‑induced colitis by modulating differentiation of Th17/Treg cells and the secretion of cytokines.
Topics: Animals; Biomarkers; Cell Differentiation; Colitis; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Glucosides; Male; Paeonia; Plant Extracts; Rats; T-Lymphocytes, Regulatory; Th17 Cells; Transcription Factors; Trinitrobenzenesulfonic Acid | 2017 |
Maydis Stigma Elicits Analgesia and Blocks Edema in Mice and Inhibits Inflammation in Macrophages.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Edema; Ethanol; Flavonoids; Flowers; Glucosides; Inflammation; Inflammation Mediators; Male; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Phytotherapy; Plant Extracts; RAW 264.7 Cells; Transcription Factor AP-1 | 2017 |
Dapagliflozin attenuates human vascular endothelial cell activation and induces vasorelaxation: A potential mechanism for inhibition of atherogenesis.
Topics: Animals; Aorta, Abdominal; Atherosclerosis; Benzhydryl Compounds; Blood Glucose; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Hypoglycemic Agents; Intercellular Adhesion Molecule-1; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; NF-kappa B; Plasminogen Activator Inhibitor 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1; Vasodilation | 2018 |
Effects of cyanidin 3-0-glucoside on cardiac structure and function in an animal model of myocardial infarction.
Topics: Animals; Anthocyanins; Disease Models, Animal; Glucosides; Heart; Humans; Male; Myocardial Infarction; Myocardium; Oryza; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley | 2017 |
Arctiin protects against cardiac hypertrophy through inhibiting MAPKs and AKT signaling pathways.
Topics: Administration, Oral; Animals; Arctium; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Fibrosis; Furans; Glucosides; Male; MAP Kinase Signaling System; Mice, Inbred C57BL; Myocytes, Cardiac; Phytotherapy; Proto-Oncogene Proteins c-akt; Signal Transduction | 2017 |
Salidroside slows the progression of EA.hy926 cell senescence by regulating the cell cycle in an atherosclerosis model.
Topics: Animals; Atherosclerosis; Biomarkers; Cell Cycle; Cell Cycle Proteins; Cell Line; Cellular Senescence; Disease Models, Animal; Endothelial Cells; Gene Expression Regulation; Genes, p53; Glucosides; Humans; Phenols | 2018 |
A natural small molecule inhibitor corilagin blocks HCV replication and modulates oxidative stress to reduce liver damage.
Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Cells, Cultured; Disease Models, Animal; Gene Expression; Genes, Reporter; Glucosides; Hepacivirus; Hepatitis C; Humans; Hydrolyzable Tannins; Liver; Liver Cirrhosis; Mice; NADPH Oxidase 4; Oxidative Stress; Plant Extracts; Rats; Reactive Oxygen Species; Signal Transduction; Transforming Growth Factor beta; Viral Nonstructural Proteins; Virus Replication | 2018 |
Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3.
Topics: Animals; Anti-Inflammatory Agents; Aorta; beta-Galactosidase; Cells, Cultured; Cellular Senescence; Collagen; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cytokines; Disease Models, Animal; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; Inflammation Mediators; Male; Mice, Inbred BALB C; Phenols; Sirtuin 3; Up-Regulation; Vascular Remodeling | 2018 |
Effects of Acanthopanax senticosus on Brain Injury Induced by Simulated Spatial Radiation in Mouse Model Based on Pharmacokinetics and Comparative Proteomics.
Topics: Animals; Brain Injuries; Computational Biology; Disease Models, Animal; Eleutherococcus; Gene Expression Profiling; Gene Ontology; Gene Regulatory Networks; Glucosides; Lignans; Male; Mice; Neuroprotective Agents; Phenylpropionates; Phytochemicals; Plant Extracts; Polysaccharides; Proteome; Proteomics; Radiation Injuries, Experimental | 2018 |
Antihypoxic activities of constituents from Arenaria kansuensis.
Topics: Animals; Arenaria Plant; Catechols; Chromatography, High Pressure Liquid; Disease Models, Animal; Flavones; Glucosides; Hypoxia; Magnetic Resonance Spectroscopy; Mice, Inbred C57BL; Plant Extracts; Plants, Medicinal | 2018 |
Polyphenolic Compounds Alter Stress-Induced Patterns of Global DNA Methylation in Brain and Blood.
Topics: Adult; Animals; Anthocyanins; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Behavior, Animal; Bone Marrow Transplantation; Brain; Caffeic Acids; Cells, Cultured; Depression; Dietary Supplements; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Glucosides; Humans; Immunity, Cellular; Leukocytes, Mononuclear; Male; Mice, Inbred C57BL; Neurons; Social Behavior; Stress, Psychological | 2018 |
Combined SGLT2 and DPP4 Inhibition Reduces the Activation of the Nlrp3/ASC Inflammasome and Attenuates the Development of Diabetic Nephropathy in Mice with Type 2 Diabetes.
Topics: Adamantane; Animals; Benzhydryl Compounds; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dipeptides; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Drug Therapy, Combination; Glucosides; Inflammasomes; Inflammation Mediators; Kidney; Male; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Signal Transduction; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2018 |
Anti-amyloidgenic and neurotrophic effects of tetrahydroxystilbene glucoside on a chronic mitochondrial dysfunction rat model induced by sodium azide.
Topics: Amyloid beta-Protein Precursor; Animals; Brain; Disease Models, Animal; Glucosides; Male; Mitochondria; Rats; Rats, Sprague-Dawley; Sodium Azide | 2018 |
Luteolin-4'-O-glucoside and its aglycone, two major flavones of Gnaphalium affine D. Don, resist hyperuricemia and acute gouty arthritis activity in animal models.
Topics: Animals; Arthritis, Gouty; Disease Models, Animal; Drugs, Chinese Herbal; Edema; Glucose Transport Proteins, Facilitative; Glucosides; Gnaphalium; Hyperuricemia; Interleukin-1beta; Kidney; Luteolin; Male; Mice, Inbred ICR; Organic Anion Transporters; Uric Acid; Xanthine Oxidase | 2018 |
Orientin and neuropathic pain in rats with spinal nerve ligation.
Topics: Animals; Astrocytes; Behavior, Animal; Cytokines; Disease Models, Animal; Flavonoids; Glucosides; Humans; Inflammation Mediators; Ligation; Microglia; Neuralgia; Neuroprotective Agents; NF-kappa B; Poaceae; Postoperative Complications; Rats; Rats, Sprague-Dawley; Signal Transduction; Spinal Nerves; Toll-Like Receptor 4 | 2018 |
Ocimum flavone Orientin as a countermeasure for thrombocytopenia.
Topics: Animals; Blood Platelets; Bone Marrow Cells; Cell Differentiation; Dietary Supplements; Disease Models, Animal; Flavonoids; Gene Expression Regulation; Glucosides; Humans; Mice; Ocimum sanctum; Phytochemicals; Thrombocytopenia; Thrombopoiesis | 2018 |
Neuroprotective effects of salidroside administration in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Disease Models, Animal; Glucosides; Glutathione; Hippocampus; Male; Malondialdehyde; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Stress; Phenols; Superoxide Dismutase | 2018 |
Effects of paeoniflorin on neurobehavior, oxidative stress, brain insulin signaling, and synaptic alterations in intracerebroventricular streptozotocin-induced cognitive impairment in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Brain; Cognitive Dysfunction; Disease Models, Animal; Electron Transport Complex IV; Glucosides; Injections, Intraventricular; Insulin; Male; Maze Learning; Membrane Potentials; Mice; Mice, Inbred C57BL; Mitochondria; Monoterpenes; Oxidative Stress; Recognition, Psychology; Signal Transduction; Streptozocin; Synapses | 2018 |
Renal outcomes with sodium glucose cotransporter 2 (SGLT2) inhibitor, dapagliflozin, in obese insulin-resistant model.
Topics: Animals; Benzhydryl Compounds; Diet, High-Fat; Disease Models, Animal; Glucosides; Humans; Insulin; Insulin Resistance; Kidney; Kidney Diseases; Male; Metformin; Obesity; Organic Anion Transporters, Sodium-Independent; Oxidative Stress; Rats; Rats, Wistar; Signal Transduction; Sodium-Glucose Transporter 2 | 2018 |
Beneficial Effect of the SGLT2 Inhibitor Empagliflozin on Glucose Homeostasis and Cardiovascular Parameters in the Cohen Rosenthal Diabetic Hypertensive (CRDH) Rat.
Topics: Animals; Benzhydryl Compounds; Biomarkers; Blood Glucose; Blood Pressure; Diabetes Mellitus; Disease Models, Animal; Glucosides; Homeostasis; Hypertension; Hypertrophy, Left Ventricular; Insulin Resistance; Kidney; Male; Pancreas; Proteinuria; Rats, Inbred SHR; Sodium-Glucose Transporter 2 Inhibitors; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2018 |
Anxiolytic-like effects of paeoniflorin in an animal model of post traumatic stress disorder.
Topics: Adrenocorticotropic Hormone; Animals; Anti-Anxiety Agents; Behavior, Animal; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, Animal; Freezing Reaction, Cataleptic; Glucosides; Hippocampus; Hydroxyindoleacetic Acid; Male; Monoterpenes; Motor Activity; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Serotonin; Stress Disorders, Post-Traumatic; Treatment Outcome | 2018 |
Renal protective effect of SGLT2 inhibitor dapagliflozin alone and in combination with irbesartan in a rat model of diabetic nephropathy.
Topics: Animals; Benzhydryl Compounds; Biomarkers; Biphenyl Compounds; Blood Pressure; Body Weight; Diabetic Nephropathies; Disease Models, Animal; Drug Therapy, Combination; Glucosides; Inflammation Mediators; Irbesartan; Kidney; Male; Organ Size; Oxidative Stress; Protective Agents; Rats, Wistar; Tetrazoles | 2018 |
Salidroside Protects Against Advanced Glycation End Products-Induced Vascular Endothelial Dysfunction.
Topics: Animals; Aorta; Apoptosis; Cell Survival; Diabetes Complications; Disease Models, Animal; Endothelial Cells; Glucosides; Glycation End Products, Advanced; Heme Oxygenase-1; Human Umbilical Vein Endothelial Cells; Humans; Male; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Phenols; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction | 2018 |
Paeoniflorin improves cardiac function and decreases adverse postinfarction left ventricular remodeling in a rat model of acute myocardial infarction.
Topics: Acute Disease; Animals; Apoptosis; Disease Models, Animal; Glucosides; Heart Function Tests; Male; Monoterpenes; Myocardial Infarction; Myocardium; Rats; Rats, Wistar; Ventricular Function, Left; Ventricular Remodeling | 2018 |
SGLT2 inhibition via dapagliflozin improves generalized vascular dysfunction and alters the gut microbiota in type 2 diabetic mice.
Topics: Animals; Benzhydryl Compounds; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Gastrointestinal Microbiome; Glucosides; Intestines; Male; Mice; Muscle, Smooth, Vascular; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Vascular Stiffness; Vasodilation | 2018 |
Paeoniflorin augments systemic Candida albicans infection through inhibiting Th1 and Th17 cell expression in a mouse model.
Topics: Animals; Candida albicans; Candidiasis; Cytokines; Disease Models, Animal; Glucosides; Kidney; Liver; Mice, Inbred BALB C; Monoterpenes; Spleen; Th1 Cells; Th17 Cells | 2018 |
Gastrodin Protects against Ethanol-Induced Liver Injury and Apoptosis in HepG2 Cells and Animal Models of Alcoholic Liver Disease.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Benzyl Alcohols; Cell Survival; Disease Models, Animal; Ethanol; Glucosides; Hep G2 Cells; Humans; Liver; Liver Diseases, Alcoholic; Male; Membrane Potential, Mitochondrial; Mice, Inbred ICR; Protective Agents; Rats, Sprague-Dawley | 2018 |
Corilagin Reduces the Frequency of Seizures and Improves Cognitive Function in a Rat Model of Chronic Epilepsy.
Topics: Animals; Biomarkers; Brain; Carbonic Anhydrases; Catalase; Cell Count; Chronic Disease; Cognition; Cytokines; Disease Models, Animal; Epilepsy; Glucosides; Hydrolyzable Tannins; Lipid Peroxidation; Male; Malondialdehyde; Maze Learning; Mitochondrial Swelling; Neurons; Nissl Bodies; Oxidative Stress; Pentylenetetrazole; Rats, Wistar; Reactive Oxygen Species; Seizures; Superoxide Dismutase | 2018 |
Unmasking a sustained negative effect of SGLT2 inhibition on body fluid volume in the rat.
Topics: Animals; Body Composition; Diabetes Mellitus, Type 2; Disease Models, Animal; Diuresis; Drinking; Eating; Epithelial Sodium Channels; Glucosides; Male; Natriuresis; Rats, Sprague-Dawley; Sodium; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Sodium-Hydrogen Exchanger 3; Thiophenes; Time Factors; Water-Electrolyte Balance | 2018 |
Paeoniflorin Attenuates Inflammatory Pain by Inhibiting Microglial Activation and Akt-NF-κB Signaling in the Central Nervous System.
Topics: Actin Cytoskeleton; Animals; Anti-Inflammatory Agents; Cell Line; Central Nervous System; Disease Models, Animal; Freund's Adjuvant; Glucosides; Inflammation; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Microglia; Monoterpenes; NF-kappa B; Pain; Proto-Oncogene Proteins c-akt; Signal Transduction; Tumor Necrosis Factor-alpha | 2018 |
[Effect and mechanism of gastrodin inhibiting β-amyloid plaques in brain of mice].
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzyl Alcohols; Brain; Disease Models, Animal; Glucosides; Memory; Memory Disorders; Mice; Mice, Transgenic; Plaque, Amyloid | 2016 |
Highly selective SGLT2 inhibitor dapagliflozin reduces seizure activity in pentylenetetrazol-induced murine model of epilepsy.
Topics: Animals; Benzhydryl Compounds; Disease Models, Animal; Epilepsy; Glucosides; Random Allocation; Rats; Sodium-Glucose Transporter 2 Inhibitors | 2018 |
Southern Brazilian native fruit shows neurochemical, metabolic and behavioral benefits in an animal model of metabolic syndrome.
Topics: Animals; Anthocyanins; Antidepressive Agents; Antioxidants; Behavior, Animal; Brazil; Catalase; Corpus Striatum; Diet, Carbohydrate Loading; Disease Models, Animal; Glucose Intolerance; Glucosides; Hippocampus; Hypoglycemic Agents; Hypolipidemic Agents; Metabolic Syndrome; Neuroprotective Agents; Oxidative Stress; Plant Extracts; Psidium; Rats; Rats, Wistar; Tandem Mass Spectrometry; Weight Gain | 2018 |
Cyanidin-3-O-β-glucoside regulates the activation and the secretion of adipokines from brown adipose tissue and alleviates diet induced fatty liver.
Topics: Adipocytes; Adipokines; Adipose Tissue, Brown; Animals; Anthocyanins; Cell Differentiation; Diet, High-Fat; Disease Models, Animal; Glucosides; Hep G2 Cells; Humans; Male; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Protective Agents | 2018 |
Dual inhibition of sodium-glucose linked cotransporters 1 and 2 exacerbates cardiac dysfunction following experimental myocardial infarction.
Topics: Animals; Benzhydryl Compounds; Carbonates; Disease Models, Animal; Glucosides; Hypertrophy, Left Ventricular; Male; Myocardial Infarction; Myocardium; Rats, Inbred F344; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2018 |
Effect of a SGLT2 inhibitor on the systemic and intrarenal renin-angiotensin system in subtotally nephrectomized rats.
Topics: Administration, Oral; Angiotensin II; Angiotensinogen; Animals; Disease Models, Animal; Glucosides; Glycosuria; Indoles; Kidney; Male; Nephrectomy; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Renin; Renin-Angiotensin System; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2018 |
Glycemic control by the SGLT2 inhibitor empagliflozin decreases aortic stiffness, renal resistivity index and kidney injury.
Topics: Albuminuria; Animals; Benzhydryl Compounds; Blood Glucose; Cell Line; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Disease Models, Animal; Endothelium, Vascular; Female; Glucosides; Glycosuria; GPI-Linked Proteins; Humans; Kidney; Mice, Inbred C57BL; Mice, Mutant Strains; Pulsatile Flow; Renal Circulation; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Vascular Resistance; Vascular Stiffness; Vasodilation | 2018 |
Paeoniflorin Ameliorates Fructose-Induced Insulin Resistance and Hepatic Steatosis by Activating LKB1/AMPK and AKT Pathways.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Biomarkers; Blood Glucose; Disease Models, Animal; Enzyme Activation; Fructose; Glucosides; Glycogen; Insulin; Insulin Resistance; Lipids; Lipogenesis; Liver; Male; Monoterpenes; Non-alcoholic Fatty Liver Disease; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction | 2018 |
SGLT2 inhibitor dapagliflozin limits podocyte damage in proteinuric nondiabetic nephropathy.
Topics: Animals; Benzhydryl Compounds; Cell Line; Disease Models, Animal; Glucosides; Humans; Injections, Intraperitoneal; Male; Mice; Podocytes; Proteinuria; Renal Insufficiency, Chronic; RNA, Small Interfering; Serum Albumin, Bovine; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2018 |
Polydatin attenuates reactive oxygen species-induced airway remodeling by promoting Nrf2-mediated antioxidant signaling in asthma mouse model.
Topics: Airway Remodeling; Animals; Antioxidants; Asthma; Cells, Cultured; Disease Models, Animal; Epithelial Cells; Epithelial-Mesenchymal Transition; Glucosides; Humans; Lung; Male; Mice; Mice, Inbred BALB C; Mice, Nude; NF-E2-Related Factor 2; Ovalbumin; Reactive Oxygen Species; Signal Transduction; Stilbenes; Transforming Growth Factor beta1 | 2019 |
The Favorable Effect of Empagliflozin on Erectile Function in an Experimental Model of Type 2 Diabetes.
Topics: Animals; Benzhydryl Compounds; Diabetes Mellitus, Type 2; Disease Models, Animal; Erectile Dysfunction; Glucosides; Male; Penile Erection; Rats; Rats, Inbred Strains; Rats, Wistar; Sodium-Glucose Transporter 2 Inhibitors | 2018 |
Salidroside and Curcumin Formula Prevents Liver Injury in Nonalcoholic Fatty Liver Disease in Rats.
Topics: AMP-Activated Protein Kinases; Animals; Biomarkers; Blood Glucose; Curcumin; Diet, High-Fat; Disease Models, Animal; Drug Combinations; Glucosides; Insulin; Insulin Resistance; Lipid Metabolism; Lipid Peroxidation; Liver; Male; Non-alcoholic Fatty Liver Disease; Phenols; Rats, Sprague-Dawley; Signal Transduction | 2018 |
Protective effects of 2,3,5,4-tetrahydroxystilbene-2-o-β-D-glucoside against osteoporosis: Current knowledge and proposed mechanisms.
Topics: 3T3 Cells; Animals; Apoptosis; Bone Density Conservation Agents; Bone Remodeling; Chemokines; Disease Models, Animal; Female; Forkhead Box Protein O3; Glucosides; Humans; Mice; Mice, Inbred BALB C; Osteoblasts; Osteoporosis, Postmenopausal; Ovariectomy; Oxidative Stress; Stilbenes; TCF Transcription Factors; Wnt Signaling Pathway | 2018 |
Protective Effects of 2,3,5,4'-Tetrahydroxystilbene-2-
Topics: Animals; Biomarkers; Body Weight; Bone and Bones; Disease Models, Animal; Glucosides; Humans; Mice; Organ Size; Osteoporosis; Ovariectomy; Plant Extracts; Protective Agents; Stilbenes; X-Ray Microtomography | 2018 |
Correlation of drug-induced and drug-related ultra-high performance liquid chromatography-mass spectrometry serum metabolomic profiles yields discovery of effective constituents of Sini decoction against myocardial ischemia in rats.
Topics: Aconitine; Alkaloids; Animals; Aspartate Aminotransferases; Catechols; Chalcone; Chromatography, High Pressure Liquid; Creatine Kinase; Disease Models, Animal; Drugs, Chinese Herbal; Fatty Alcohols; Flavanones; Glucosides; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Malondialdehyde; Mass Spectrometry; Metabolome; Myocardial Ischemia; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2018 |
Parkin-mediated mitophagy as a potential therapeutic target for intervertebral disc degeneration.
Topics: Animals; Apoptosis; Autophagy; Cells, Cultured; Disease Models, Animal; Disease Progression; Gene Knockdown Techniques; Glucosides; Humans; Intervertebral Disc Degeneration; Male; Mitochondria; Mitophagy; Nucleus Pulposus; Phenols; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Transfection; Tumor Necrosis Factor-alpha; Ubiquitin-Protein Ligases; Up-Regulation | 2018 |
Frontline Science: Reprogramming COX-2, 5-LOX, and CYP4A-mediated arachidonic acid metabolism in macrophages by salidroside alleviates gouty arthritis.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arthritis, Gouty; Cell Movement; Cell Polarity; Chondrocytes; Crystallization; Cyclooxygenase 2; Cytochrome P-450 CYP4A; Disease Models, Animal; Down-Regulation; Glucosides; Interleukin-1beta; Macrophages; Male; Mice; Models, Biological; Neutrophils; NF-kappa B; Phenols; Phenotype; Rabbits; Rats, Wistar; RAW 264.7 Cells; Signal Transduction; STAT1 Transcription Factor; Synovial Fluid; Tumor Necrosis Factor-alpha; Uric Acid | 2019 |
Early administration of dapagliflozin preserves pancreatic β-cell mass through a legacy effect in a mouse model of type 2 diabetes.
Topics: Animals; Benzhydryl Compounds; Biomarkers; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucosides; Insulin; Insulin-Secreting Cells; Male; Mice; Sodium-Glucose Transporter 2 Inhibitors | 2019 |
Single dose of empagliflozin increases in vivo cardiac energy status in diabetic db/db mice.
Topics: Adenosine Triphosphate; Animals; Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus; Disease Models, Animal; Energy Metabolism; Glucosides; Ketones; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Phosphocreatine; Sodium-Glucose Transporter 2 Inhibitors; Ventricular Function | 2018 |
Empagliflozin directly improves diastolic function in human heart failure.
Topics: Animals; Benzhydryl Compounds; Biopsy; Diastole; Disease Models, Animal; Echocardiography; Female; Glucosides; Heart Failure; Heart Ventricles; Humans; Male; Mice; Middle Aged; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Rats; Rats, Zucker; Sodium-Glucose Transporter 2 Inhibitors; Ventricular Function, Left | 2018 |
Polydatin suppresses nucleus pulposus cell senescence, promotes matrix homeostasis and attenuates intervertebral disc degeneration in rats.
Topics: ADAMTS4 Protein; Aggrecans; Animals; Cells, Cultured; Cellular Senescence; Collagen; Disease Models, Animal; Extracellular Matrix; Glucosides; Humans; Intervertebral Disc; Intervertebral Disc Degeneration; Low Back Pain; Matrix Metalloproteinase 13; Matrix Metalloproteinase 3; NF-E2-Related Factor 2; Nucleus Pulposus; Rats; Stilbenes; Tumor Necrosis Factor-alpha | 2018 |
Syringaresinol‑di‑O‑β‑D‑glucoside, a phenolic compound from Polygonatum sibiricum, exhibits an antidiabetic and antioxidative effect on a streptozotocin‑induced mouse model of diabetes.
Topics: Animals; Antioxidants; Biomarkers; Body Weight; Diabetes Mellitus, Experimental; Disease Models, Animal; Fasting; Glucosides; Hypoglycemic Agents; Insulin; Kidney; Lignans; Liver; Male; Mice; Plant Extracts; Polygonatum | 2018 |
The flaxseed lignan secoisolariciresinol diglucoside decreases local inflammation, suppresses NFκB signaling, and inhibits mammary tumor growth.
Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents; Biomarkers; Butylene Glycols; Cell Line, Tumor; Cell Survival; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Flax; Gene Expression Profiling; Glucosides; Immunohistochemistry; Lignans; Mammary Neoplasms, Animal; Mice; NF-kappa B; Signal Transduction | 2019 |
Salidroside improves the hypoxic tumor microenvironment and reverses the drug resistance of platinum drugs via HIF-1α signaling pathway.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Survival; Computational Biology; Disease Models, Animal; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Gene Expression Profiling; Glucosides; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Mice; Phenols; Signal Transduction; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2018 |
SGLT1 in pancreatic α cells regulates glucagon secretion in mice, possibly explaining the distinct effects of SGLT2 inhibitors on plasma glucagon levels.
Topics: Animals; Benzhydryl Compounds; Blood Glucose; Canagliflozin; Diabetes Mellitus; Diet, High-Fat; Disease Models, Animal; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Glucose; Glucosides; Glycosuria; Hypoglycemic Agents; Insulin; Male; Mice; Mice, Inbred C57BL; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2019 |
Polydatin effectively attenuates disease activity in lupus-prone mouse models by blocking ROS-mediated NET formation.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Disease Progression; Drugs, Chinese Herbal; Extracellular Traps; Female; Glucosides; Humans; Lupus Erythematosus, Systemic; Mice; Mice, Inbred BALB C; Reactive Oxygen Species; Stilbenes; Treatment Outcome | 2018 |
Pterostilbene 4'-
Topics: Acute Lung Injury; Animals; Antioxidants; Disease Models, Animal; Enzyme Induction; Epithelial Cells; Glucosides; Heme Oxygenase-1; Humans; Inflammation; Lipopolysaccharides; Lung; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pseudomonas aeruginosa; RAW 264.7 Cells; RNA, Messenger; Stilbenes; Up-Regulation | 2018 |
A SGLT2 inhibitor dapagliflozin suppresses prolonged ventricular-repolarization through augmentation of mitochondrial function in insulin-resistant metabolic syndrome rats.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Benzhydryl Compounds; Blood Glucose; Disease Models, Animal; Glucosides; Heart Rate; Heart Ventricles; Insulin; Insulin Resistance; Male; Membrane Potential, Mitochondrial; Metabolic Syndrome; Mitochondria, Heart; Myocytes, Cardiac; Potassium Channels, Voltage-Gated; Rats, Wistar; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Ventricular Function, Left; Voltage-Gated Sodium Channels | 2018 |
Effect of salidroside on bone marrow haematopoiesis in a mouse model of myelosuppressed anaemia.
Topics: Anemia; Animals; Bone Marrow; Bone Marrow Transplantation; Cell Count; Cell Lineage; Cell Proliferation; Disease Models, Animal; Glucosides; Hematopoiesis; Hematopoietic Stem Cells; Immunosuppression Therapy; Male; Mice; Pancytopenia; Phenols; Survival Analysis | 2019 |
Pharmacokinetic studies unveiled the drug-drug interaction between trans-2,3,5,4'-tetrahydroxystilbene-2-O-β-d-glucopyranoside and emodin that may contribute to the idiosyncratic hepatotoxicity of Polygoni Multiflori Radix.
Topics: Administration, Oral; Animals; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Disease Models, Animal; Drug Interactions; Drugs, Chinese Herbal; Emodin; Glucosides; Humans; Male; Plant Roots; Polygonum; Rats; Rats, Sprague-Dawley; Stilbenes; Tandem Mass Spectrometry | 2019 |
Luteoloside attenuates neuroinflammation in focal cerebral ischemia in rats via regulation of the PPARγ/Nrf2/NF-κB signaling pathway.
Topics: Animals; Anti-Inflammatory Agents; Brain Ischemia; Cells, Cultured; Cyclooxygenase 2; Disease Models, Animal; Glucosides; Humans; Infarction, Middle Cerebral Artery; Interleukin-1beta; Luteolin; Male; Neurogenic Inflammation; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide Synthase Type II; PPAR gamma; Rats; Rats, Sprague-Dawley; Signal Transduction; Tumor Necrosis Factor-alpha | 2019 |
Protective effect of forsythoside B against lipopolysaccharide-induced acute lung injury by attenuating the TLR4/NF-κB pathway.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Caffeic Acids; Cytokines; Disease Models, Animal; Female; Glucosides; Inflammation; Lipopolysaccharides; Lung; Macrophages; Male; Mice; Mice, Inbred BALB C; NF-kappa B; RAW 264.7 Cells; Signal Transduction; Toll-Like Receptor 4 | 2019 |
The Protective Effects of 2,3,5,4'-Tetrahydroxystilbene-2-
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell Count; Cytokines; Disease Models, Animal; Female; Glucosides; Immunoglobulin Class Switching; Inflammation; Inflammation Mediators; Lung; Mice, Inbred C57BL; Ovalbumin; Protective Agents; Respiratory Hypersensitivity; Stilbenes; Th1 Cells; Th2 Cells | 2018 |
Chemically synthesized Secoisolariciresinol diglucoside (LGM2605) improves mitochondrial function in cardiac myocytes and alleviates septic cardiomyopathy.
Topics: Animals; Antioxidants; Autophagy; Biomarkers; Butylene Glycols; Calcium; Cardiomyopathies; Cecum; Cell Line; Cytokines; Disease Models, Animal; Gene Expression Regulation; Glucosides; Humans; Inflammation Mediators; Ligation; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Mitochondria, Heart; Myocardium; Myocytes, Cardiac; NF-kappa B; Organelle Biogenesis; Oxidative Stress; Oxygen Consumption; Punctures; Sepsis | 2019 |
[Activity Study of Icarlin and Epimedin C Monomer under the Same Molarity in Osteoporosis Ze- brafish Model].
Topics: Animals; Disease Models, Animal; Flavonoids; Glucosides; Osteoporosis; Zebrafish | 2016 |
Delayed ischaemic contracture onset by empagliflozin associates with NHE1 inhibition and is dependent on insulin in isolated mouse hearts.
Topics: Animals; Benzhydryl Compounds; Disease Models, Animal; Glucosides; Guanidines; Insulin; Isolated Heart Preparation; Male; Mice, Inbred C57BL; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Signal Transduction; Sodium-Glucose Transporter 2 Inhibitors; Sodium-Hydrogen Exchanger 1; Sulfones; Time Factors | 2019 |
Improvement of diabetic wound healing by topical application of Vicenin-2 hydrocolloid film on Sprague Dawley rats.
Topics: Alginates; Animals; Apigenin; Bandages, Hydrocolloid; Diabetic Foot; Disease Models, Animal; Glucosides; Male; Rats; Rats, Sprague-Dawley; Wound Healing | 2019 |
Salidroside promotes rat spinal cord injury recovery by inhibiting inflammatory cytokine expression and NF-κB and MAPK signaling pathways.
Topics: Animals; Astrocytes; Cytokines; Disease Models, Animal; Gene Expression Regulation; Glucosides; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phenols; Rats; Signal Transduction; Spinal Cord Injuries; Tumor Necrosis Factor-alpha | 2019 |
Cyanidin-3-O-β-glucoside attenuates allergic airway inflammation by modulating the IL-4Rα-STAT6 signaling pathway in a murine asthma model.
Topics: Allergens; Animals; Anthocyanins; Anti-Inflammatory Agents; Asthma; Cytokines; Dietary Supplements; Disease Models, Animal; Female; Glucosides; Humans; Lung; Mice; Mice, Inbred BALB C; Ovalbumin; Receptors, Cell Surface; Respiratory Hypersensitivity; STAT6 Transcription Factor; Th2 Cells | 2019 |
Curculigoside exerts significant anti‑arthritic effects in vivo and in vitro via regulation of the JAK/STAT/NF‑κB signaling pathway.
Topics: Animals; Arthritis, Rheumatoid; Benzoates; Cell Proliferation; Collagen Type II; Disease Models, Animal; Gene Expression; Glucosides; Humans; I-kappa B Proteins; Interleukins; Janus Kinase 1; Janus Kinase 3; Rats; Signal Transduction; STAT3 Transcription Factor; Synoviocytes; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2019 |
Salidroside stimulates the Sirt1/PGC-1α axis and ameliorates diabetic nephropathy in mice.
Topics: Animals; Diabetic Nephropathies; Disease Models, Animal; DNA, Mitochondrial; Electron Transport; Glucosides; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Mitochondria; Phenols; Podocytes; Sirtuin 1; Streptozocin; Transcription Factors; Up-Regulation | 2019 |
A study in a rat initiation-promotion bladder tumour model demonstrated no promoter/progressor potential of dapagliflozin.
Topics: Administration, Oral; Animals; Benzhydryl Compounds; Butylhydroxybutylnitrosamine; Disease Models, Animal; Dose-Response Relationship, Drug; Glucosides; Male; Rats; Rats, Sprague-Dawley; Urinary Bladder Neoplasms | 2019 |
Phillyrin is an effective inhibitor of quorum sensing with potential as an anti-Pseudomonas aeruginosa infection therapy.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Caenorhabditis elegans; Disease Models, Animal; Glucosides; Glycolipids; Male; Pancreatic Elastase; Pseudomonas aeruginosa; Pseudomonas Infections; Pyocyanine; Quorum Sensing | 2019 |
Dapagliflozin Attenuates Cardiac Remodeling in Mice Model of Cardiac Pressure Overload.
Topics: Animals; Benzhydryl Compounds; Blotting, Western; Cardiomyopathies; Disease Models, Animal; Echocardiography; Fibrosis; Glucosides; Heart Ventricles; Hypertrophy, Left Ventricular; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Sodium-Glucose Transport Proteins; Sodium-Glucose Transporter 2 Inhibitors; Ventricular Function, Left; Ventricular Pressure; Ventricular Remodeling | 2019 |
Acteoside ameliorates inflammatory responses through NFkB pathway in alcohol induced hepatic damage.
Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Ethanol; Female; Glucosides; Hep G2 Cells; Hepatitis, Alcoholic; Humans; I-kappa B Proteins; Lamiaceae; Liver; NF-kappa B; Phenols; Plant Leaves; Rats; Rats, Wistar; Signal Transduction; Toxicity Tests, Acute; Treatment Outcome | 2019 |
Dehydration and insulinopenia are necessary and sufficient for euglycemic ketoacidosis in SGLT2 inhibitor-treated rats.
Topics: Animals; Benzhydryl Compounds; Dehydration; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucocorticoids; Glucose; Glucosides; Humans; Insulin; Ketosis; Lipolysis; Liver; Male; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Sodium-Glucose Transporter 2 Inhibitors | 2019 |
SGLT2 inhibition with empagliflozin attenuates myocardial oxidative stress and fibrosis in diabetic mice heart.
Topics: Animals; Antioxidant Response Elements; Antioxidants; Benzhydryl Compounds; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Disease Models, Animal; Fibrosis; Glucosides; Mice, Inbred C57BL; Myocardium; NF-E2-Related Factor 2; Oxidative Stress; Phosphorylation; Signal Transduction; Smad Proteins; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Transforming Growth Factor beta1; Ventricular Function, Left; Ventricular Remodeling | 2019 |
Post-stroke gastrodin treatment ameliorates ischemic injury and increases neurogenesis and restores the Wnt/β-Catenin signaling in focal cerebral ischemia in mice.
Topics: Animals; Apoptosis; Benzyl Alcohols; beta Catenin; Brain; Brain Ischemia; Disease Models, Animal; Doublecortin Protein; Glucosides; Infarction, Middle Cerebral Artery; Ischemia; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Neuroprotective Agents; Stroke; Wnt Signaling Pathway | 2019 |
RNA-seq analysis of diet-driven obesity and anti-obesity effects of quercetin glucoside or epigallocatechin gallate in Drosophila adults.
Topics: Animals; Anti-Obesity Agents; Body Weight; Catechin; Diet, High-Fat; Disease Models, Animal; Drosophila; Drug Evaluation, Preclinical; Female; Gene Expression Regulation; Glucosides; Humans; Lipid Metabolism; Male; Metabolomics; Obesity; Oxidative Stress; Quercetin; RNA-Seq; RNA, Messenger; Species Specificity | 2019 |
Antidepressant-like effects of paeoniflorin on post-stroke depression in a rat model.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; CA1 Region, Hippocampal; Cyclic AMP Response Element-Binding Protein; Depressive Disorder; Disease Models, Animal; Fluoxetine; Glucosides; Male; Monoterpenes; Random Allocation; Rats, Sprague-Dawley; Stress, Psychological; Stroke | 2019 |
Gastrodin attenuates neuroinflammation in DOI-induce Tourette syndrome in rats.
Topics: Amphetamines; Animals; Behavior, Animal; Benzyl Alcohols; Cytokines; Disease Models, Animal; Glucosides; Inflammation; Male; MAP Kinase Signaling System; Rats; Rats, Sprague-Dawley; Tourette Syndrome | 2019 |
Dental Pulp Stem Cell Transplantation with 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside Accelerates Alveolar Bone Regeneration in Rats.
Topics: Adolescent; Adult; Alveolar Bone Loss; Alveolar Process; Animals; Bone Regeneration; Cell Differentiation; Dental Pulp; Disease Models, Animal; Female; Glucosides; Humans; Male; Osteogenesis; Rats, Sprague-Dawley; Regenerative Medicine; Stem Cell Transplantation; Stem Cells; Stilbenes; Stimulation, Chemical; Young Adult | 2019 |
The sodium-glucose co-transporter 2 inhibitor empagliflozin attenuates cardiac fibrosis and improves ventricular hemodynamics in hypertensive heart failure rats.
Topics: Animals; Atrial Function, Left; Atrial Natriuretic Factor; Benzhydryl Compounds; Diet, High-Fat; Disease Models, Animal; Fatty Acids; Fibrosis; Gene Expression Regulation; Glucosides; Heart Failure; Hemodynamics; Hypertension; Male; Myocardium; Natriuretic Peptide, Brain; Rats, Inbred SHR; Rats, Inbred WKY; Recovery of Function; Sodium-Glucose Transporter 2 Inhibitors; Tumor Necrosis Factor-alpha; Ventricular Function, Left; Ventricular Remodeling | 2019 |
The phytochemical polydatin ameliorates non-alcoholic steatohepatitis by restoring lysosomal function and autophagic flux.
Topics: Animals; Autophagy; Disease Models, Animal; Glucosides; Humans; Lysosomes; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Protective Agents; Signal Transduction; Stilbenes | 2019 |
Inhibition of apoptosis signal-regulating kinase by paeoniflorin attenuates neuroinflammation and ameliorates neuropathic pain.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Disease Models, Animal; Down-Regulation; Encephalitis; Glucosides; Hydroxyquinolines; Hyperalgesia; Interleukin-1beta; Male; MAP Kinase Kinase Kinase 5; Monoterpenes; Pain Threshold; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Signal Transduction | 2019 |
Dereplication of Components Coupled with HPLC-qTOF-MS in the Active Fraction of
Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Flavones; Gene Expression Regulation; Glucosides; Humans; Humulus; Magnetic Resonance Spectroscopy; Mice; Monoamine Oxidase; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Plant Extracts; Tandem Mass Spectrometry | 2019 |
Inhibition of sodium glucose cotransporter 2 (SGLT2) delays liver fibrosis in a medaka model of nonalcoholic steatohepatitis (NASH).
Topics: Animals; Benzhydryl Compounds; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Fish Proteins; Glucosides; Liver; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease; Oryzias; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2019 |
Empagliflozin Ameliorates Adverse Left Ventricular Remodeling in Nondiabetic Heart Failure by Enhancing Myocardial Energetics.
Topics: Analysis of Variance; Animals; Benzhydryl Compounds; Diabetes Mellitus; Disease Models, Animal; Echocardiography, Three-Dimensional; Glucosides; Heart Failure; Heart Function Tests; Random Allocation; Reference Values; Sodium-Glucose Transporter 2 Inhibitors; Statistics, Nonparametric; Stroke Volume; Swine; Treatment Outcome; Ventricular Function, Left; Ventricular Remodeling | 2019 |
Plantamajoside attenuates isoproterenol-induced cardiac hypertrophy associated with the HDAC2 and AKT/ GSK-3β signaling pathway.
Topics: Animals; Cardiomegaly; Catechols; Cell Line; Cell Survival; Disease Models, Animal; Glucosides; Glycogen Synthase Kinase 3 beta; Heart Ventricles; Histone Deacetylase 2; Isoproterenol; Male; Mice; Mice, Inbred BALB C; Myocardium; Myocytes, Cardiac; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction | 2019 |
Lipid Modulating Anti-oxidant Stress Activity of Gastrodin on Nonalcoholic Fatty Liver Disease Larval Zebrafish Model.
Topics: Animals; Antioxidants; Benzyl Alcohols; Disease Models, Animal; Gastrodia; Gene Expression Regulation; Glucosides; Larva; Lipid Metabolism; Non-alcoholic Fatty Liver Disease; Zebrafish | 2019 |
Curculigoside facilitates fear extinction and prevents depression-like behaviors in a mouse learned helplessness model through increasing hippocampal BDNF.
Topics: Animals; Behavior, Animal; Benzoates; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Glucosides; Helplessness, Learned; Hippocampus; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred C57BL | 2019 |
Effects of Paeoniflorin on the activity of muscle strips, intracellular calcium ion concentration and L‑type voltage‑sensitive calcium ion channels in the sphincter of Oddi of hypercholesterolemic rabbits.
Topics: Action Potentials; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Calcium Channels, L-Type; Cholesterol; Disease Models, Animal; Female; Glucosides; Hypercholesterolemia; Male; Monoterpenes; Muscle Tonus; Muscles; Patch-Clamp Techniques; Rabbits; Sphincter of Oddi | 2019 |
Potential protective effects of Dapagliflozin in gentamicin induced nephrotoxicity rat model via modulation of apoptosis associated miRNAs.
Topics: Acute Kidney Injury; Animals; Apoptosis; Benzhydryl Compounds; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Gentamicins; Glucosides; Kidney Function Tests; Male; MicroRNAs; Oxidative Stress; Rats; Rats, Wistar | 2019 |
Cognitive-enhancing and ameliorative effects of acanthoside B in a scopolamine-induced amnesic mouse model through regulation of oxidative/inflammatory/cholinergic systems and activation of the TrkB/CREB/BDNF pathway.
Topics: Amnesia; Animals; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Furans; Glucosides; Inflammation; Lignans; Membrane Glycoproteins; Mice; Oxidation-Reduction; Protein-Tyrosine Kinases; Receptors, Cholinergic; Scopolamine | 2019 |
Promoting neurogenesis in hippocampal dentate gyrus of chronic unpredictable stress-induced depressive-like rats with paeoniflorin.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Chronic Disease; Dentate Gyrus; Depressive Disorder; Disease Models, Animal; Glucosides; Imipramine; Male; Monoterpenes; Neurogenesis; Random Allocation; Rats, Sprague-Dawley; Receptor, trkB; RNA, Messenger; Stress, Psychological; Uncertainty | 2019 |
A Protective Role of Paeoniflorin in Fluctuant Hyperglycemia-Induced Vascular Endothelial Injuries through Antioxidative and Anti-Inflammatory Effects and Reduction of PKC
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Hyperglycemia; Inflammation; Male; Monoterpenes; Oxidative Stress; Protective Agents; Protein Kinase C beta; Rats, Sprague-Dawley; Vascular System Injuries | 2019 |
Grape Peel Extract and Resveratrol Inhibit Wrinkle Formation in Mice Model Through Activation of Nrf2/HO-1 Signaling Pathway.
Topics: Animals; Antioxidants; Disease Models, Animal; Female; Flavonoids; Fruit; Glucosides; Heme Oxygenase-1; Humans; Mice; Mice, Hairless; NF-E2-Related Factor 2; Plant Extracts; Resveratrol; Signal Transduction; Skin Aging; Stilbenes; Ultraviolet Rays; Vitis | 2019 |
Effects of dapagliflozin in experimental sepsis model in rats.
Topics: Animals; Benzhydryl Compounds; Disease Models, Animal; Glucosides; Oxidative Stress; Rats; Sepsis; Tissue Distribution | 2019 |
Protective Effect of Acteoside on Ovariectomy-Induced Bone Loss in Mice.
Topics: Animals; Biomarkers; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Disease Models, Animal; Female; Glucosides; Mice; Models, Biological; Organ Size; Osteoporosis; Ovariectomy; Phenols; Protective Agents; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; TNF Receptor-Associated Factor 6 | 2019 |
Ipragliflozin-induced adipose expansion inhibits cuff-induced vascular remodeling in mice.
Topics: Adipocytes; Adipogenesis; Adipose Tissue; Adiposity; Animals; Cells, Cultured; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Fibrosis; Glucosides; Inflammation Mediators; Insulin Resistance; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Obesity; Paracrine Communication; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Vascular Remodeling; Vascular System Injuries | 2019 |
Dynamic Alterations in the Gut Microbiota of Collagen-Induced Arthritis Rats Following the Prolonged Administration of Total Glucosides of Paeony.
Topics: Animals; Ankle Joint; Arthritis, Experimental; Arthritis, Rheumatoid; Bacteria; Body Weight; Collagen; Cytokines; Disease Models, Animal; Drugs, Chinese Herbal; Dysbiosis; Feces; Gastrointestinal Microbiome; Glucosides; Immunity; Immunity, Mucosal; Immunoglobulin A, Secretory; Immunomodulation; Inflammation; Interferon-gamma; Male; Paeonia; Rats; Rats, Sprague-Dawley; Symbiosis; T-Lymphocytes, Regulatory; Th1 Cells; Th17 Cells; Th2 Cells; Vascular Endothelial Growth Factor A | 2019 |
Cardiac ischemia-reperfusion injury under insulin-resistant conditions: SGLT1 but not SGLT2 plays a compensatory protective role in diet-induced obesity.
Topics: Animals; Benzhydryl Compounds; Blood Glucose; Canagliflozin; Diet, High-Fat; Disease Models, Animal; Glucose Transporter Type 4; Glucosides; Insulin Resistance; Isolated Heart Preparation; Male; Mice, Inbred C57BL; Myocardial Reperfusion Injury; Myocytes, Cardiac; Obesity; Phlorhizin; Signal Transduction; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2019 |
Therapy of empagliflozin plus metformin on T2DM mice shows no higher amelioration for glucose and lipid metabolism than empagliflozin monotherapy.
Topics: Animals; Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Therapy, Combination; Glucose; Glucosides; Lipid Metabolism; Male; Metformin; Mice; Mice, Inbred C57BL; Sodium-Glucose Transporter 2 Inhibitors; Treatment Outcome | 2019 |
Cucurbitacin E glucoside from
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Citrullus colocynthis; Cyclin D1; Disease Models, Animal; Glucosides; Male; Mice; Prostatic Hyperplasia; Testosterone; Triterpenes | 2021 |
Deciphering the multicomponent synergy mechanisms of SiNiSan prescription on irritable bowel syndrome using a bioinformatics/network topology based strategy.
Topics: Animals; Computational Biology; Data Mining; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Synergism; Drugs, Chinese Herbal; Flavanones; Glucosides; Humans; Irritable Bowel Syndrome; Male; Medicine, Chinese Traditional; Molecular Docking Simulation; Monoterpenes; Protein Interaction Maps; Proteins; Rats, Sprague-Dawley; Signal Transduction | 2019 |
In vitro and in vivo inhibitory effects of TLR4 agonist, glucopyranosyl lipid A (GLA), on allergic rhinitis caused by Japanese cedar pollen.
Topics: Allergens; Animals; Antigens, Plant; Cells, Cultured; Cryptomeria; Disease Models, Animal; Glucosides; Humans; Immunotherapy; Japan; Leukocytes, Mononuclear; Lipid A; Mice; Mice, Inbred BALB C; Plant Proteins; Pollen; Rhinitis, Allergic, Seasonal; Toll-Like Receptor 4; Treatment Outcome | 2020 |
Total glucosides of paeony attenuates animal psoriasis induced inflammatory response through inhibiting STAT1 and STAT3 phosphorylation.
Topics: Animals; Cytokines; Disease Models, Animal; Female; Glucosides; Guinea Pigs; Imiquimod; Male; Mice, Inbred BALB C; Nuclear Receptor Subfamily 1, Group F, Member 3; Paeonia; Phosphorylation; Plant Roots; Psoriasis; STAT1 Transcription Factor; STAT3 Transcription Factor | 2019 |
Role of sodium/glucose cotransporter inhibition on a rat model of angiotensin II-dependent kidney damage.
Topics: Acute Kidney Injury; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzhydryl Compounds; Blood Pressure; Disease Models, Animal; Glomerular Filtration Rate; Glucose; Glucosides; Hypertension; Losartan; Male; Microvilli; Proteinuria; Rats; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2019 |
Protection by salidroside against bone loss via inhibition of oxidative stress and bone-resorbing mediators.
Topics: Adaptor Proteins, Signal Transducing; Alkaline Phosphatase; Animals; Bone and Bones; Bone Density Conservation Agents; Bone Resorption; Cell Survival; Collagen Type I; Collagen Type I, alpha 1 Chain; Disease Models, Animal; Female; Glucosides; Humans; Interleukin-6; Membrane Proteins; Mice; Osteoblasts; Osteocalcin; Osteoclasts; Osteoporosis; Phenols; Plant Extracts; RANK Ligand; Reactive Oxygen Species; Rhodiola; Transcription, Genetic | 2013 |
Hypoglycemic action of borapetoside A from the plant Tinospora crispa in mice.
Topics: Animals; Blood Glucose; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Diterpenes; Gluconeogenesis; Glucose; Glucosides; Glycogen; Hypoglycemic Agents; Insulin; Interleukin-6; Liver; Male; Mice; Mice, Inbred ICR; Muscles; Phosphoenolpyruvate Carboxykinase (GTP); Phytotherapy; Plant Extracts; Plants, Medicinal; Signal Transduction; Tinospora | 2013 |
Emodin-6-O-β-D-glucoside down-regulates endothelial protein C receptor shedding.
Topics: ADAM Proteins; ADAM17 Protein; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Emodin; Endothelial Protein C Receptor; Endothelium, Vascular; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Injections, Intravenous; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Molecular Targeted Therapy; Receptors, Cell Surface; Sepsis; Solubility | 2013 |
Hepatoprotective effects of syringin on fulminant hepatic failure induced by D-galactosamine and lipopolysaccharide in mice.
Topics: Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Eleutherococcus; Galactosamine; Glucosides; Lipopolysaccharides; Liver Failure, Acute; Liver Function Tests; Mice; Mice, Inbred BALB C; Phenylpropionates; Protective Agents; Survival Analysis | 2014 |
Anti-inflammatory and anti-oxidative effects of corilagin in a rat model of acute cholestasis.
Topics: Acute Disease; Alanine Transaminase; Analysis of Variance; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Bilirubin; Cholagogues and Choleretics; Cholestasis; Dexamethasone; Disease Models, Animal; Glucosides; Hydrolyzable Tannins; Liver; Male; Malondialdehyde; NF-kappa B; Nitric Oxide; Oxidative Stress; Peroxidase; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Ursodeoxycholic Acid | 2013 |
[Effects of polydatin on ALT, AST, TNF-alpha, and COX-2 in sepsis model mice].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cyclooxygenase 2; Disease Models, Animal; Glucosides; Liver; Mice; Mice, Inbred Strains; Sepsis; Stilbenes; Tumor Necrosis Factor-alpha | 2013 |
[Effects of four kinds of Chinese medicine monomer on growth of PANC-1 xenograft tumor and studying of molecular mechanism].
Topics: Animals; Benzylisoquinolines; Caspase 3; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drugs, Chinese Herbal; Flavonoids; Gene Expression Regulation, Neoplastic; Glucosides; Humans; Male; Mice; Mice, Nude; Phenols; Random Allocation; RNA, Messenger; RNA, Neoplasm; Saponins; Steroids; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2013 |
Tofogliflozin, a novel sodium-glucose co-transporter 2 inhibitor, improves renal and pancreatic function in db/db mice.
Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Animals; Benzhydryl Compounds; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Female; Glucosides; Glycated Hemoglobin; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Kidney; Losartan; Mice; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Time Factors | 2013 |
Gastrodin ameliorates Parkinson's disease by downregulating connexin 43.
Topics: Animals; Astrocytes; Benzyl Alcohols; Cell Communication; Connexin 43; Disease Models, Animal; Down-Regulation; Gap Junctions; Gene Expression Regulation; Glucosides; Parkinson Disease; Phosphorylation; Rats; Rotenone | 2013 |
Paeoniflorin suppresses vascular damage and the expression of E-selectin and ICAM-1 in a mouse model of cutaneous Arthus reaction.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigen-Antibody Complex; Arthus Reaction; Autoimmunity; Benzoates; Bridged-Ring Compounds; Cell Adhesion; Cells, Cultured; Disease Models, Animal; E-Selectin; Endothelial Cells; Gene Expression Regulation; Glucosides; Humans; Inflammation; Intercellular Adhesion Molecule-1; Leukocytes; Male; MAP Kinase Kinase 4; Mice; Mice, Inbred BALB C; Microcirculation; Monoterpenes; p38 Mitogen-Activated Protein Kinases; Real-Time Polymerase Chain Reaction; Skin; Tumor Necrosis Factor-alpha; Vascular Diseases | 2013 |
The aqueous extract of Lycopus lucidus Turcz ameliorates streptozotocin-induced diabetic renal damage via inhibiting TGF-β1 signaling pathway.
Topics: Animals; Caffeic Acids; Cell Line; Cinnamates; Depsides; Diabetic Nephropathies; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Glucosides; Humans; Luteolin; Lycopus; Male; Mice; Phosphorylation; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Rosmarinic Acid; Signal Transduction; Streptozocin; Transforming Growth Factor beta1 | 2013 |
Orcinol glucoside produces antidepressant effects by blocking the behavioural and neuronal deficits caused by chronic stress.
Topics: Animals; Antidepressive Agents; Chronic Disease; Corticosterone; Corticotropin-Releasing Hormone; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Food Preferences; Glucosides; Hindlimb Suspension; Male; MAP Kinase Signaling System; Rats; Rats, Sprague-Dawley; Resorcinols; Stress, Psychological; Sucrose; Sweetening Agents; Swimming | 2014 |
Polydatin attenuated food allergy via store-operated calcium channels in mast cell.
Topics: Animals; Calcium; Calcium Channels; Disease Models, Animal; Drugs, Chinese Herbal; Female; Food Hypersensitivity; Glucosides; Histamine; Immunoglobulin E; Interleukin-4; Intestine, Small; Mast Cells; Ovalbumin; Rats; Rats, Inbred BN; Stilbenes | 2013 |
Cyanidin-3-glucoside extracted from mulberry fruit can reduce N-methyl-N-nitrosourea-induced retinal degeneration in rats.
Topics: Alkylating Agents; Animals; Anthocyanins; Apoptosis; Disease Models, Animal; Electroretinography; Glucosides; Male; Methylnitrosourea; Morus; Night Vision; Photoreceptor Cells, Vertebrate; Plant Extracts; Rats; Rats, Sprague-Dawley; Retinal Degeneration | 2014 |
Neuroprotection by tetrahydroxystilbene glucoside in the MPTP mouse model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apoptosis Regulatory Proteins; Ataxia; Behavior, Animal; Cell Survival; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Glucosides; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuroprotective Agents; Parkinson Disease; Proto-Oncogene Proteins c-akt; Signal Transduction; Stilbenes; Substantia Nigra; Tyrosine 3-Monooxygenase | 2013 |
Paeoniflorin, the main active constituent of Paeonia lactiflora roots, attenuates bleomycin-induced pulmonary fibrosis in mice by suppressing the synthesis of type I collagen.
Topics: Animals; Benzoates; Bleomycin; Bridged-Ring Compounds; Collagen Type I; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glucosides; Lung; Male; Mice; Mice, Inbred ICR; Molecular Structure; Monoterpenes; Paeonia; Plant Roots; Pulmonary Fibrosis | 2013 |
Gastrodin ameliorates anxiety-like behaviors and inhibits IL-1beta level and p38 MAPK phosphorylation of hippocampus in the rat model of posttraumatic stress disorder.
Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzyl Alcohols; Disease Models, Animal; Drugs, Chinese Herbal; Glucosides; Hippocampus; Interleukin-1beta; Interleukin-6; Male; Motor Activity; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Stress Disorders, Post-Traumatic; Time Factors | 2013 |
Quercetin glucosides promote ischemia-induced angiogenesis, but do not promote tumor growth.
Topics: Angiogenesis Inducing Agents; Animals; Antioxidants; Capillaries; Cytokines; Disease Models, Animal; Glucosides; Hindlimb; Ischemia; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Mutant Strains; Neoplasms; Neovascularization, Pathologic; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Quercetin | 2013 |
Emodin-6-O-β-D--glucoside inhibits high-glucose-induced vascular inflammation.
Topics: Animals; Anti-Inflammatory Agents; Capillary Permeability; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Coculture Techniques; Diabetic Angiopathies; Disease Models, Animal; Dose-Response Relationship, Drug; Emodin; Endothelial Cells; Glucose; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred C57BL; Monocytes; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Vasculitis | 2014 |
Total glucosides of paeony inhibit the proliferation of fibroblast-like synoviocytes through the regulation of G proteins in rats with collagen-induced arthritis.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Cell Proliferation; Cells, Cultured; Chickens; Collagen Type II; Cyclic AMP; Disease Models, Animal; Fibroblasts; Glucosides; GTP-Binding Proteins; Humans; Male; Paeonia; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Signal Transduction; Synovial Membrane | 2014 |
Possible mechanism involved in the antinociceptive activity of dimer of paederosidic acid and paederosidic acid methyl ester in mice.
Topics: Analgesics; Analysis of Variance; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Formaldehyde; Glucosides; Heterocyclic Compounds, 2-Ring; Hyperalgesia; Mice; Mice, Inbred ICR; Morphine; Pain; Pain Measurement; Pain Threshold; Time Factors | 2014 |
[Comparative study on effects of blood enriching on mouse model of blood deficiency syndrome induced by compound method of bleeding, starved feeding and exhausting of Paeoniae Radix Alba and Paeoniae Radix Rubra, paeoniflorin and albiflorin].
Topics: Animals; Benzoates; Bridged-Ring Compounds; Disease Models, Animal; Drugs, Chinese Herbal; Erythrocytes; Glucosides; Hemoglobins; Male; Mice; Monoterpenes; Paeonia | 2013 |
SGLT2 selective inhibitor ipragliflozin reduces body fat mass by increasing fatty acid oxidation in high-fat diet-induced obese rats.
Topics: Adiposity; Animals; Anti-Obesity Agents; Biomarkers; Blood Glucose; Diet, High-Fat; Disease Models, Animal; Energy Metabolism; Fatty Acids; Glucosides; Glycosuria; Hypoglycemic Agents; Lipid Metabolism; Obesity; Oxidation-Reduction; Rats; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Time Factors; Up-Regulation; Weight Loss | 2014 |
Gastrodin ameliorates depression-like behaviors and up-regulates proliferation of hippocampal-derived neural stem cells in rats: involvement of its anti-inflammatory action.
Topics: Animals; Antidepressive Agents; Benzyl Alcohols; Cell Survival; Cells, Cultured; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Embryo, Mammalian; Food Preferences; Glucosides; Hippocampus; Male; Maze Learning; Neural Stem Cells; Rats; Stress, Psychological; Sucrose; Swimming; Up-Regulation | 2014 |
Isolation, characterization and antihyperlipidemic activity of secoisolariciresinol diglucoside in poloxamer-407-induced experimental hyperlipidemia.
Topics: Animals; Butylene Glycols; Chromatography, Thin Layer; Disease Models, Animal; Flax; Glucosides; Hyperlipidemias; Hypolipidemic Agents; Lipids; Mice; Poloxamer; Rats; Spectrum Analysis | 2014 |
Gastrodin alleviates memory deficits and reduces neuropathology in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Benzyl Alcohols; Brain; Cytokines; Disease Models, Animal; Glucosides; Maze Learning; Memory Disorders; Mice; Mice, Transgenic; Microglia; Neuroprotective Agents; RNA, Messenger | 2014 |
Total glucosides of paeony attenuate renal tubulointerstitial injury in STZ-induced diabetic rats: role of Toll-like receptor 2.
Topics: Actins; Administration, Oral; Animals; Anti-Inflammatory Agents; Biomarkers; Cadherins; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucosides; Immunohistochemistry; Kidney; Macrophage Activation; Male; Molecular Conformation; Nephritis, Interstitial; NF-kappa B; Paeonia; Phytotherapy; Rats; Rats, Wistar; Streptozocin; Toll-Like Receptor 2 | 2014 |
Cyanidin-3-O-β-glucoside inhibits lipopolysaccharide-induced inflammatory response in mouse mastitis model.
Topics: Animals; Anthocyanins; Cytokines; Disease Models, Animal; Female; Glucosides; Humans; Lipopolysaccharides; Mammary Glands, Animal; Mastitis; Mice | 2014 |
Zucker Diabetic Fatty rats exhibit hypercoagulability and accelerated thrombus formation in the Arterio-Venous shunt model of thrombosis.
Topics: Animals; Arteriovenous Shunt, Surgical; Benzhydryl Compounds; Blood Coagulation; Diabetes Complications; Diabetes Mellitus, Type 2; Disease Models, Animal; Factor Xa Inhibitors; Female; Glucosides; Hypoglycemic Agents; Platelet Aggregation; Pyrazoles; Pyridones; Rats; Rats, Zucker; Thrombophilia; Thrombosis | 2014 |
Influence of lactuside B on the expression of AQP4 and TRPM7 mRNAs in the cerebral cortex after cerebral ischemia injury.
Topics: Animals; Aquaporin 4; Brain Edema; Cerebral Cortex; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Drug Administration Schedule; Glucosides; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium; Time Factors; TRPM Cation Channels | 2014 |
8-O-acetyl shanzhiside methylester attenuates cerebral ischaemia/reperfusion injury through an anti-inflammatory mechanism in diabetic rats.
Topics: Animals; Anti-Inflammatory Agents; Blood-Brain Barrier; Brain Ischemia; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucosides; HMGB1 Protein; Male; NF-kappa B; Peroxidase; Pyrans; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factor-alpha | 2014 |
Sesquiterpenoids from Pittocaulon filare.
Topics: Animals; Anti-Inflammatory Agents; Asteraceae; Disease Models, Animal; Edema; Glucosides; Indomethacin; Mexico; Neutrophil Infiltration; Neutrophils; Nuclear Magnetic Resonance, Biomolecular; Peroxidase; Sesquiterpenes; Stereoisomerism; Tetradecanoylphorbol Acetate | 2014 |
Calycosin-7-O-β-D-glucoside regulates nitric oxide /caveolin-1/matrix metalloproteinases pathway and protects blood-brain barrier integrity in experimental cerebral ischemia-reperfusion injury.
Topics: Animals; Astragalus Plant; Blood-Brain Barrier; Brain Ischemia; Caveolin 1; Disease Models, Animal; Glucosides; Isoflavones; Male; Matrix Metalloproteinases; Microvessels; Neuroprotective Agents; Nitric Oxide; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tight Junction Proteins; Time Factors | 2014 |
The SGLT2 inhibitor empagliflozin ameliorates early features of diabetic nephropathy in BTBR ob/ob type 2 diabetic mice with and without hypertension.
Topics: Albuminuria; Animals; Benzhydryl Compounds; Blood Glucose; Comorbidity; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Female; Glucosides; Hypertension; Hypertrophy; Hypoglycemic Agents; Kidney; Mice; Mice, Obese; Obesity; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2014 |
Long-term treatment with the sodium glucose cotransporter 2 inhibitor, dapagliflozin, ameliorates glucose homeostasis and diabetic nephropathy in db/db mice.
Topics: Animals; Apoptosis; Benzhydryl Compounds; Blood Glucose; Body Weight; Cells, Cultured; Diabetic Nephropathies; Disease Models, Animal; Gene Expression; Glomerular Mesangium; Glucose; Glucosides; Homeostasis; Inflammation; Insulin-Secreting Cells; Kidney; Kidney Cortex; Kidney Function Tests; Kidney Tubules, Proximal; Macrophages; Male; Mice; Oxidative Stress; Sodium-Glucose Transporter 2 Inhibitors | 2014 |
Metformin supports the antidiabetic effect of a sodium glucose cotransporter 2 inhibitor by suppressing endogenous glucose production in diabetic mice.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Therapy, Combination; Glucose; Glucose Clamp Technique; Glucosides; Glycated Hemoglobin; Hyperglycemia; Hypoglycemic Agents; Metformin; Mice, Knockout; Mice, Obese; Obesity; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2015 |
[Effect of paeoniflorin on level of glucocorticoid receptor of peripheral blood monocytes in rats of collagen-induced arthritis].
Topics: Animals; Arthritis; Cattle; Collagen; Disease Models, Animal; Drugs, Chinese Herbal; Glucosides; Humans; Leukocytes, Mononuclear; Male; Monoterpenes; Rats; Rats, Wistar; Receptors, Glucocorticoid | 2014 |
[Safety assessment of stevia rebaudiana bertoni grown in southeastern Mexico as food sweetener].
Topics: Adolescent; Adult; Animals; Blood Glucose; Cells, Cultured; Disease Models, Animal; Glucose Tolerance Test; Glucosides; Humans; Mexico; Plant Extracts; Rats; Stevia; Sweetening Agents; Vero Cells; Young Adult | 2014 |
Protective effect of polydatin on learning and memory impairments in neonatal rats with hypoxic‑ischemic brain injury by up‑regulating brain‑derived neurotrophic factor.
Topics: Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Glucosides; Hippocampus; Hypoxia-Ischemia, Brain; Learning; Memory; Memory Disorders; Protective Agents; Rats; Rats, Sprague-Dawley; Stilbenes; Up-Regulation | 2014 |
Dual regulating effects of gastrodin on extracellular dopamine concentration in rats models of Tourette's syndrome.
Topics: Animals; Apomorphine; Benzyl Alcohols; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Down-Regulation; Glucosides; Haloperidol; Homovanillic Acid; Male; Nitriles; Rats; Stereotyped Behavior; Tourette Syndrome; Up-Regulation | 2015 |
Verbascoside promotes apoptosis by regulating HIPK2-p53 signaling in human colorectal cancer.
Topics: Adult; Aged; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Disease Models, Animal; Female; Gene Expression; Glucosides; Heterografts; Humans; Male; Mice; Middle Aged; Neoplasm Grading; Neoplasm Metastasis; Neoplasm Staging; Phenols; Protein Serine-Threonine Kinases; Signal Transduction; Tumor Suppressor Protein p53 | 2014 |
Paeoniflorin attenuates Aβ25-35-induced neurotoxicity in PC12 cells by preventing mitochondrial dysfunction.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Cell Survival; Disease Models, Animal; Glucosides; Membrane Potential, Mitochondrial; Mitochondria; Monoterpenes; Neurons; Neuroprotective Agents; PC12 Cells; Peptide Fragments; Rats | 2014 |
Polydatin supplementation ameliorates diet-induced development of insulin resistance and hepatic steatosis in rats.
Topics: Adiponectin; Animals; Body Weight; Diet; Dietary Supplements; Disease Models, Animal; Fatty Liver; Gene Expression; Glucose Tolerance Test; Glucosides; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Leptin; Liver; Male; Rats; Stilbenes | 2015 |
Salidroside attenuates allergic airway inflammation through negative regulation of nuclear factor-kappa B and p38 mitogen-activated protein kinase.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Down-Regulation; Female; Gene Expression; Glucosides; Lung; Mice, Inbred BALB C; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phenols; Phytotherapy | 2014 |
Cyanidin 3-O-β-D-Glucoside Improves Bone Indices.
Topics: Animals; Anthocyanins; Bone and Bones; Bone Density; Bone Density Conservation Agents; Diet; Disease Models, Animal; Female; Femur; Fruit; Glucosides; Humans; Lumbar Vertebrae; Osteoporosis, Postmenopausal; Ovariectomy; Phytotherapy; Plant Extracts; Rats, Sprague-Dawley; Rubus; Tibia | 2015 |
Searching for synergistic bronchodilators and novel therapeutic regimens for chronic lung diseases from a traditional Chinese medicine, Qingfei Xiaoyan Wan.
Topics: Adrenergic beta-2 Receptor Agonists; Animals; Asthma; Bronchodilator Agents; Calcium; Cell Line; Chromatography, High Pressure Liquid; Chronic Disease; Disease Models, Animal; Drug Synergism; Drugs, Chinese Herbal; Ephedrine; Flavonoids; Furans; Glucosides; Guinea Pigs; Humans; Lactones; Lignans; Lung Diseases; Medicine, Chinese Traditional; Myocytes, Smooth Muscle; Trachea | 2014 |
Paeoniflorin attenuates allergic inflammation in asthmatic mice.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chemokine CCL11; Cytokines; Disease Models, Animal; Down-Regulation; Female; Glucosides; Inflammation Mediators; Lung; Mice; Mice, Inbred BALB C; Monoterpenes; Paeonia | 2015 |
Polydatin prevents hypertrophy in phenylephrine induced neonatal mouse cardiomyocytes and pressure-overload mouse models.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cardiomegaly; Cardiotonic Agents; Cell Size; Cells, Cultured; Disease Models, Animal; Drugs, Chinese Herbal; Glucosides; Heart Failure; Heart Ventricles; Male; Mice, Inbred C57BL; Oxidative Stress; Phenylephrine; Rats; rho-Associated Kinases; Stilbenes; Ventricular Remodeling | 2015 |
Osteoprotective effect of geraniin against ovariectomy-induced bone loss in rats.
Topics: Alkaline Phosphatase; Animals; Bone Density; Calcitonin; Calcium; Disease Models, Animal; Estradiol; Female; Femur; Glucosides; Hydrolyzable Tannins; Osteoporosis; Ovariectomy; Rats; Rats, Wistar | 2015 |
Stevia-derived compounds attenuate the toxic effects of ectopic lipid accumulation in the liver of obese mice: a transcriptomic and metabolomic study.
Topics: Amino Acids; Animals; Bile Acids and Salts; Disease Models, Animal; Diterpenes, Kaurane; Fatty Liver; Glucose; Glucosides; Glutathione; Insulin Resistance; Lipid Metabolism; Liver; Male; Metabolomics; Mice; Mice, Obese; Obesity; Oxidative Stress; Peroxisome Proliferator-Activated Receptors; Plant Preparations; Stevia; Transcriptome | 2015 |
Effects of total glucosides of peony on AQP-5 and its mRNA expression in submandibular glands of NOD mice with Sjogren's syndrome.
Topics: Animals; Aquaporin 5; Disease Models, Animal; Female; Glucosides; Mice; Mice, Inbred NOD; Paeonia; Random Allocation; RNA, Messenger; Sjogren's Syndrome; Submandibular Gland | 2015 |
Polydatin attenuates ipopolysaccharide-induced acute lung injury in rats.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Apoptosis; Blotting, Western; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Glucosides; In Situ Nick-End Labeling; Inflammation; Lipopolysaccharides; Male; Rats; Rats, Sprague-Dawley; Stilbenes | 2014 |
Salidroside alleviates paraquat-induced rat acute lung injury by repressing TGF-β1 expression.
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Glucosides; Herbicides; Immunohistochemistry; Lung; Male; Paraquat; Phenols; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Transforming Growth Factor beta1 | 2014 |
Oral administration of paeoniflorin attenuates allergic contact dermatitis by inhibiting dendritic cell migration and Th1 and Th17 differentiation in a mouse model.
Topics: Administration, Oral; Animals; Cell Differentiation; Cell Movement; Cytokines; Dendritic Cells; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Disease Models, Animal; Female; Glucosides; Lymph Nodes; Mice, Inbred BALB C; Monoterpenes; RNA, Messenger; Skin; Th1 Cells; Th17 Cells | 2015 |
Anthocyanin-rich black elderberry extract improves markers of HDL function and reduces aortic cholesterol in hyperlipidemic mice.
Topics: Alanine Transaminase; Animals; Anthocyanins; Apolipoprotein A-I; Apolipoproteins B; Aryldialkylphosphatase; Aspartate Aminotransferases; Biomarkers; Blood Glucose; Body Weight; Chemokine CCL2; Cholesterol, HDL; Chromatography, High Pressure Liquid; Disaccharides; Disease Models, Animal; Glucosides; Hyperlipidemias; Intestinal Mucosa; Intestines; Male; Mice; Mice, Knockout; Plant Extracts; Sambucus nigra; Thiobarbituric Acid Reactive Substances; Triglycerides | 2015 |
Salidroside attenuates chronic hypoxia-induced pulmonary hypertension via adenosine A2a receptor related mitochondria-dependent apoptosis pathway.
Topics: Animals; Apoptosis; Disease Models, Animal; Gene Expression; Glucosides; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Lung; Male; Mice; Mitochondria; Myocytes, Smooth Muscle; Phenols; Pulmonary Artery; Receptor, Adenosine A2A; RNA, Messenger; Signal Transduction; Vascular Remodeling | 2015 |
Orientin improves depression-like behavior and BDNF in chronic stressed mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Flavonoids; Glucosides; Hippocampus; Male; Mice; Neuronal Plasticity; Norepinephrine; Oxidative Stress; Serotonin; Stress, Psychological; Synaptic Transmission | 2015 |
Salidroside prevents cognitive impairment induced by chronic cerebral hypoperfusion in rats.
Topics: Animals; Brain Ischemia; Brain Waves; Carotid Arteries; Carotid Stenosis; Cerebrovascular Circulation; Cognition Disorders; Dementia, Vascular; Disease Models, Animal; Glucosides; Hippocampus; Male; Maze Learning; Phenols; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Rhodiola | 2015 |
Memory Enhancement of Acteoside (Verbascoside) in a Senescent Mice Model Induced by a Combination of D-gal and AlCl3.
Topics: Administration, Oral; Aging; Aluminum Chloride; Aluminum Compounds; Animals; Chlorides; Cognition Disorders; Disease Models, Animal; Galactose; Glucosides; Hippocampus; Memory; Memory Disorders; Mice; Nerve Growth Factors; Phenols; Receptor, trkA | 2015 |
The Mechanism of Memory Enhancement of Acteoside (Verbascoside) in the Senescent Mouse Model Induced by a Combination of D-gal and AlCl3.
Topics: Aging; Aluminum Chloride; Aluminum Compounds; Animals; Antioxidants; Caspase 3; Chlorides; Cistanche; Disease Models, Animal; Galactose; Glucosides; Hippocampus; Memory; Memory Disorders; Mice; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; Phenols; Vitamin E | 2015 |
D(-)-Salicin inhibits the LPS-induced inflammation in RAW264.7 cells and mouse models.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Benzyl Alcohols; Cell Line; Disease Models, Animal; Edema; Extracellular Signal-Regulated MAP Kinases; Glucosides; Inflammation; Lipopolysaccharides; Macrophages; Male; Medicine, Traditional; Mice; Mice, Inbred BALB C; NF-kappa B; Signal Transduction | 2015 |
Salidroside-Mediated Neuroprotection is Associated with Induction of Early Growth Response Genes (Egrs) Across a Wide Therapeutic Window.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Brain; Brain Ischemia; Caspase 3; Disease Models, Animal; Dose-Response Relationship, Drug; Early Growth Response Transcription Factors; Glucosides; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; PC12 Cells; Phenols; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stroke; Time Factors | 2015 |
[Anti-hyperuricemia effect and mechanism of polydatin in mice].
Topics: Animals; Disease Models, Animal; Glucosides; Hyperuricemia; Kidney; Mice; Stilbenes; Uric Acid | 2014 |
Effect of Sodium-Glucose Cotransport Inhibition on Polycystic Kidney Disease Progression in PCK Rats.
Topics: Albuminuria; Animals; Benzhydryl Compounds; Biopsy; Body Weight; Cell Proliferation; Cyclic AMP; Disease Models, Animal; Disease Progression; Diuresis; Electrolytes; Epithelial Cells; Glucosides; Kidney; Kidney Function Tests; Male; Polycystic Kidney Diseases; Rats; Sodium-Glucose Transport Proteins; Ultrasonography | 2015 |
Immunoregulatory Effects of Paeoniflorin Exerts Anti-asthmatic Effects via Modulation of the Th1/Th2 Equilibrium.
Topics: Airway Resistance; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Female; GATA3 Transcription Factor; Glucosides; Immunoglobulin E; Interferon-gamma; Interleukin-4; Lung; Mice, Inbred BALB C; Monoterpenes; Ovalbumin; Phytotherapy; Plants, Medicinal; Pulmonary Eosinophilia; T-Box Domain Proteins; Th1 Cells; Th1-Th2 Balance; Th2 Cells | 2015 |
Pain Modulation by Lignans (Phyllanthin and Hypophyllanthin) and Tannin (Corilagin) Rich Extracts of Phyllanthus amarus in Carrageenan-induced Thermal and Mechanical Chronic Muscle Hyperalgesia.
Topics: Animals; Carrageenan; Dinoprostone; Disease Models, Animal; Glucosides; Hydrolyzable Tannins; Hyperalgesia; Inflammation; Lignans; Male; Muscle, Skeletal; Musculoskeletal Pain; Pain; Phyllanthus; Rats, Wistar | 2015 |
Effects of Flaxseed Lignan Secoisolariciresinol Diglucosideon Preneoplastic Biomarkers of Cancer Progression in a Model of Simultaneous Breast and Ovarian Cancer Development.
Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Butylene Glycols; Cell Adhesion; Disease Models, Animal; Disease Progression; Drug Evaluation, Preclinical; Estrogen Receptor Modulators; Female; Flax; Glucosides; Ki-67 Antigen; Ovarian Neoplasms; Phytoestrogens; Precancerous Conditions; Rats; Rats, Inbred ACI; Seeds | 2015 |
Anti-oxidant polydatin (piceid) protects against substantia nigral motor degeneration in multiple rodent models of Parkinson's disease.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Dopaminergic Neurons; Glucosides; Male; Mice, Inbred C57BL; Motor Neurons; Nerve Degeneration; Neuroprotective Agents; Oxidants; Oxidative Stress; Parkinson Disease; Rats, Sprague-Dawley; Stilbenes; Substantia Nigra | 2015 |
Antidiabetic Effects of Aqueous Infusions of Artemisia herba-alba and Ajuga iva in Alloxan-Induced Diabetic Rats.
Topics: Ajuga; Alloxan; Animals; Apigenin; Artemisia; Blood Glucose; Chlorogenic Acid; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucosides; Glyburide; Hypoglycemic Agents; Medicine, Traditional; Molecular Structure; Plants, Medicinal; Polyphenols; Rats; Rats, Wistar | 2015 |
Total glucosides of peony attenuates experimental autoimmune encephalomyelitis in C57BL/6 mice.
Topics: Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Immunologic; Encephalomyelitis, Autoimmune, Experimental; Enzyme-Linked Immunosorbent Assay; Female; Freund's Adjuvant; Glucosides; Mice; Mice, Inbred C57BL; Myelin-Oligodendrocyte Glycoprotein; Paeonia; Peptide Fragments; Pertussis Toxin; Phytotherapy; RNA, Messenger; Spinal Cord; Transcription Factors | 2015 |
Paeoniflorin ameliorates acute myocardial infarction of rats by inhibiting inflammation and inducible nitric oxide synthase signaling pathways.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Caspase 3; Caspase 9; Creatine Kinase; Creatine Kinase, MB Form; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Glucosides; Inflammation; L-Lactate Dehydrogenase; Medicine, Chinese Traditional; Monoterpenes; Myocardial Infarction; NF-kappa B; Nitric Oxide Synthase Type II; Paeonia; Rats; Rats, Sprague-Dawley; Signal Transduction; Troponin T | 2015 |
Paeoniflorin Atttenuates Amyloidogenesis and the Inflammatory Responses in a Transgenic Mouse Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Glucosides; Inflammation; Inflammation Mediators; Male; Memory Disorders; Mice; Mice, Transgenic; Monoterpenes; Paeonia; Plaque, Amyloid; Presenilin-1 | 2015 |
Cyanidin-3-O-β-glucoside Purified from Black Rice Protects Mice against Hepatic Fibrosis Induced by Carbon Tetrachloride via Inhibiting Hepatic Stellate Cell Activation.
Topics: Animals; Anthocyanins; Carbon Tetrachloride; Cytokines; Disease Models, Animal; Glucosides; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Oryza; Oxidative Stress; Plant Extracts; Protective Agents | 2015 |
Polydatin protects hepatocytes against mitochondrial injury in acute severe hemorrhagic shock via SIRT1-SOD2 pathway.
Topics: Animals; Cyclosporine; Disease Models, Animal; Glucosides; Hepatocytes; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Resveratrol; Shock, Hemorrhagic; Sirtuin 1; Stilbenes; Superoxide Dismutase | 2015 |
Ameliorative Effect of Vicenin-2 and Scolymoside on TGFBIp-Induced Septic Responses.
Topics: Animals; Anti-Inflammatory Agents; Apigenin; Capillary Permeability; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Chemotaxis, Leukocyte; Cyclopia Plant; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Extracellular Matrix Proteins; Extracellular Signal-Regulated MAP Kinases; Glucosides; Human Umbilical Vein Endothelial Cells; Inflammation Mediators; Luteolin; Male; Mice, Inbred C57BL; Neutrophils; Phytotherapy; Plant Extracts; Plants, Medicinal; Pulmonary Edema; Sepsis; Time Factors; Transforming Growth Factor beta | 2015 |
Salidroside Mitigates Sepsis-Induced Myocarditis in Rats by Regulating IGF-1/PI3K/Akt/GSK-3β Signaling.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Glucosides; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Inflammation Mediators; Insulin-Like Growth Factor I; Lipopolysaccharides; Male; Myocarditis; Myocardium; Phenols; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Sepsis; Signal Transduction | 2015 |
Cyanidin-3-O-glucoside attenuates acute lung injury in sepsis rats.
Topics: Acute Lung Injury; Animals; Anthocyanins; Disease Models, Animal; Drug Evaluation, Preclinical; Glucosides; Lung; Male; NF-kappa B; Oxidative Stress; Random Allocation; Rats, Sprague-Dawley; Sepsis | 2015 |
Activating mitochondrial function and haemoglobin expression with EH-201, an inducer of erythropoietin in neuronal cells, reverses memory impairment.
Topics: Animals; Astrocytes; Cells, Cultured; Disease Models, Animal; Erythropoietin; Female; Glucosides; Hemoglobins; Hydrogen Peroxide; Kainic Acid; Male; Memory Disorders; Mice, Inbred C57BL; Mitochondria; Neuroprotective Agents; PC12 Cells; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Reactive Oxygen Species; Stilbenes; Succinate Dehydrogenase; Transcription Factors | 2015 |
Osmanthus fragrans Flower Extract and Acteoside Protect Against d-Galactose-Induced Aging in an ICR Mouse Model.
Topics: Aging; Animals; Disease Models, Animal; Flowers; Galactose; Glucosides; Humans; Magnoliopsida; Male; Memory; Mice; Mice, Inbred ICR; Phenols; Plant Extracts; Protective Agents | 2016 |
Salidroside ameliorates cognitive impairment in a d-galactose-induced rat model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; bcl-2-Associated X Protein; Carrier Proteins; Caspase 9; Cell Cycle Proteins; Cognition Disorders; Cytokines; Disease Models, Animal; Down-Regulation; Escape Reaction; Galactose; Glucosides; Hippocampus; Male; Maze Learning; Phenols; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Time Factors; Up-Regulation | 2015 |
Paeoniflorin exerts a nephroprotective effect on concanavalin A-induced damage through inhibition of macrophage infiltration.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Chemical and Drug Induced Liver Injury; Chemokine CXCL11; Concanavalin A; Disease Models, Animal; Female; Glucosides; Immunohistochemistry; Kidney; Macrophages; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Monoterpenes; Real-Time Polymerase Chain Reaction; Receptors, CXCR3 | 2015 |
Anti-Inflammatory activities of licorice extract and its active compounds, glycyrrhizic acid, liquiritin and liquiritigenin, in BV2 cells and mice liver.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cell Line; Disease Models, Animal; Flavanones; Glucosides; Glycyrrhiza; Glycyrrhizic Acid; Inflammation; Inflammation Mediators; Liver; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Oxidative Stress; Plant Extracts; Tumor Necrosis Factor-alpha | 2015 |
Neuroprotective effects of 3-O-demethylswertipunicoside against MPTP-induced Parkinson's disease in vivo and its antioxidant properties in vitro.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Biphenyl Compounds; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Glucosides; Hippocampus; Hydroxyl Radical; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Motor Activity; MPTP Poisoning; Neuroprotective Agents; Picrates; Spine; Superoxides; Tyrosine 3-Monooxygenase; Xanthones | 2015 |
Tetrahydroxy stilbene glucoside improved the behavioral disorders of APP695V717I transgenic mice by inhibiting the expression of Beclin-1 and LC3-II.
Topics: Alzheimer Disease; Animals; Apoptosis Regulatory Proteins; Beclin-1; Behavior, Animal; Disease Models, Animal; Female; Glucosides; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Stilbenes | 2015 |
Polydatin Alleviates Small Intestine Injury during Hemorrhagic Shock as a SIRT1 Activator.
Topics: Animals; Apoptosis; Disease Models, Animal; Drugs, Chinese Herbal; Female; Glucosides; Humans; Intestine, Small; Oxidative Stress; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Stilbenes | 2015 |
4'-O-β-D-glucosyl-5-O-methylvisamminol, an active ingredient of Saposhnikovia divaricata, attenuates high-mobility group box 1 and subarachnoid hemorrhage-induced vasospasm in a rat model.
Topics: Animals; Apiaceae; Caspase 3; Caspase 9; Cell Movement; Chromones; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Glucosides; HMGB1 Protein; Leukocytes; Male; Neuroprotective Agents; Rats; Subarachnoid Hemorrhage; Vasospasm, Intracranial | 2015 |
Involvement of the GABAergic system in the neuroprotective and sedative effects of acacetin 7-O-glucoside in rodents.
Topics: Animals; Anticonvulsants; CA1 Region, Hippocampal; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Flavonoids; gamma-Aminobutyric Acid; Glucosides; Hemiplegia; Hypnotics and Sedatives; Male; Mice; Motor Activity; Neuroprotective Agents; Rats, Wistar; Recovery of Function; Seizures; Tissue Culture Techniques | 2015 |
Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside in the MPTP-induced mouse model of Parkinson's disease: Involvement of reactive oxygen species-mediated JNK, P38 and mitochondrial pathways.
Topics: Animals; Apoptosis Regulatory Proteins; Behavior, Animal; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Glucosides; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Mice; Mitochondria; Neuroprotective Agents; Parkinsonian Disorders; Phosphorylation; Reactive Oxygen Species; Stilbenes; Tyrosine 3-Monooxygenase | 2015 |
Polydatin Inhibits Mitochondrial Dysfunction in the Renal Tubular Epithelial Cells of a Rat Model of Sepsis-Induced Acute Kidney Injury.
Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Drugs, Chinese Herbal; Epithelial Cells; Glucosides; Kidney Tubules; Membrane Potential, Mitochondrial; Mitochondria; Rats; Rats, Sprague-Dawley; Sepsis; Stilbenes | 2015 |
A novel HSV-2 subunit vaccine induces GLA-dependent CD4 and CD8 T cell responses and protective immunity in mice and guinea pigs.
Topics: Adjuvants, Immunologic; Animals; Antibodies, Neutralizing; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Disease Models, Animal; Female; Glucosides; Guinea Pigs; Herpes Genitalis; Herpesvirus 2, Human; Herpesvirus Vaccines; Immunologic Memory; Lipid A; Mice, Inbred C57BL; Treatment Outcome; Vaccines, Subunit; Vaccines, Synthetic | 2016 |
Nephroprotective Effects of Polydatin against Ischemia/Reperfusion Injury: A Role for the PI3K/Akt Signal Pathway.
Topics: Animals; Antioxidants; Cyclooxygenase 2; Disease Models, Animal; Glucosides; Interleukin-1beta; Kidney; Male; Mice; Mice, Inbred BALB C; Nitric Oxide Synthase Type II; Oxidative Stress; Oxidoreductases; Phosphatidylinositol 3-Kinases; Protective Agents; Proto-Oncogene Proteins c-akt; Reperfusion Injury; Signal Transduction; Stilbenes; Tumor Necrosis Factor-alpha; Up-Regulation | 2015 |
Amelioration of Hyperglycemia with a Sodium-Glucose Cotransporter 2 Inhibitor Prevents Macrophage-Driven Atherosclerosis through Macrophage Foam Cell Formation Suppression in Type 1 and Type 2 Diabetic Mice.
Topics: Animals; Atherosclerosis; Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Foam Cells; Gene Expression; Glucose Tolerance Test; Glucosides; Hyperglycemia; Hypoglycemic Agents; Macrophages, Peritoneal; Male; Mice; Mice, Knockout; Sodium-Glucose Transporter 2 Inhibitors | 2015 |
High glucose induces rat mesangial cells proliferation and MCP-1 expression via ROS-mediated activation of NF-κB pathway, which is inhibited by eleutheroside E.
Topics: Animals; Cell Proliferation; Chemokine CCL2; Diabetic Nephropathies; Disease Models, Animal; Gene Expression Regulation; Glucose; Glucosides; Humans; I-kappa B Proteins; Lignans; Mesangial Cells; NADPH Oxidases; NF-kappa B; NF-KappaB Inhibitor alpha; Rats; Reactive Oxygen Species; Signal Transduction; Transcription Factor RelA | 2016 |
Flaxseed lignans enriched in secoisolariciresinol diglucoside prevent acute asbestos-induced peritoneal inflammation in mice.
Topics: Animals; Antioxidants; Asbestos, Crocidolite; Butylene Glycols; Chromatography, Liquid; Diet; Dietary Supplements; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Flax; Glucosides; Inflammation; Lignans; Mesothelioma; Mice; Mice, Mutant Strains; Oxidative Stress; Peritoneal Lavage; Peritoneum; Precancerous Conditions; Reverse Transcriptase Polymerase Chain Reaction; Seeds; Tandem Mass Spectrometry; Transcriptome | 2016 |
Pretreatment with the compound asperuloside decreases acute lung injury via inhibiting MAPK and NF-κB signaling in a murine model.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Cell Line; Cyclopentane Monoterpenes; Disease Models, Animal; Drugs, Chinese Herbal; Glucosides; Humans; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred BALB C; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Peroxidase; Pyrans; Signal Transduction; Tumor Necrosis Factor-alpha | 2016 |
The Selective SGLT2 Inhibitor Ipragliflozin Has a Therapeutic Effect on Nonalcoholic Steatohepatitis in Mice.
Topics: Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucosides; Hypoglycemic Agents; Insulin Resistance; Mice; Non-alcoholic Fatty Liver Disease; Obesity; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Treatment Outcome | 2016 |
Sodium-Glucose Linked Cotransporter-2 Inhibition Does Not Attenuate Disease Progression in the Rat Remnant Kidney Model of Chronic Kidney Disease.
Topics: Animals; Benzhydryl Compounds; Disease Models, Animal; Disease Progression; Fibrosis; Gene Expression; Glomerular Filtration Rate; Glucosides; Glycosuria; Humans; Hypertension, Renal; Hypoglycemic Agents; Kidney; Male; Nephrectomy; Proteinuria; Rats; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; RNA, Messenger; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Transforming Growth Factor beta1; Treatment Failure | 2016 |
Protective effect of paeoniflorin on inflammation and apoptosis in the cerebral cortex of a transgenic mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cerebral Cortex; Cognition; Disease Models, Animal; Glucosides; Inflammation; Mice, Transgenic; Monoterpenes; Neuroprotective Agents; Phosphorylation; Proto-Oncogene Proteins c-akt | 2016 |
Gastrodin improves cognitive dysfunction and decreases oxidative stress in vascular dementia rats induced by chronic ischemia.
Topics: Alcohol Dehydrogenase; Animals; Antioxidants; Apoptosis; Behavior, Animal; Benzyl Alcohols; Brain; Brain Ischemia; Cell Line, Tumor; Cerebrovascular Circulation; Chronic Disease; Cognition; Dementia, Vascular; Disease Models, Animal; Dose-Response Relationship, Drug; Glucosides; Glutathione Peroxidase; Humans; Male; Malondialdehyde; Maze Learning; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Rats, Wistar; Reactive Oxygen Species; Sulfhydryl Compounds; Time Factors | 2015 |
Polydatin ameliorates lipid and glucose metabolism in type 2 diabetes mellitus by downregulating proprotein convertase subtilisin/kexin type 9 (PCSK9).
Topics: Animals; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Down-Regulation; Drugs, Chinese Herbal; Female; Germinal Center Kinases; Glucosides; Hep G2 Cells; Hepatocytes; Humans; Hydrogen Bonding; Hypoglycemic Agents; Insulin Resistance; Lipid Metabolism; Lipids; Liver; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Palmitic Acid; Proprotein Convertase 9; Proprotein Convertases; Protein Binding; Protein Conformation; Protein Serine-Threonine Kinases; Receptors, LDL; RNA Interference; Serine Endopeptidases; Stilbenes; Time Factors; Transfection | 2016 |
Possible effects of Phillyrea latifolia on weight loss in rats fed a high-energy diet.
Topics: Animals; Anti-Obesity Agents; Biomarkers; Blood Glucose; Chlorogenic Acid; Diet, High-Fat; Disease Models, Animal; Energy Intake; Glucosides; Hypoglycemic Agents; Intestine, Small; Lipids; Liver; Luteolin; Male; Obesity; Oleaceae; Phytotherapy; Plant Extracts; Plant Leaves; Plants, Medicinal; Rats, Wistar; Time Factors; Weight Loss | 2016 |
4'-O-β-D-Glucosyl-5-O-Methylvisamminol, A Natural Histone H3 Phosphorylation Epigenetic Suppressor, Exerts a Neuroprotective Effect Through PI3K/Akt Signaling Pathway on Focal Cerebral Ischemia in Rats.
Topics: Animals; Apoptosis; Brain; Caspase 3; Caspase 9; Chromones; Disease Models, Animal; Epigenesis, Genetic; Glucosides; Histones; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Random Allocation; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction | 2016 |
[Effects of Electroacupuncture Intervention Combined with Gastrodin on Expression of Proteins Related to Proliferation-differentiation of Neural Stem Cells in Hippocampal CA 1 and CA 3 Regions in Focal Cerebral Ischemia Rats].
Topics: Animals; Benzyl Alcohols; Brain Ischemia; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Cell Differentiation; Cell Proliferation; Combined Modality Therapy; Disease Models, Animal; Drugs, Chinese Herbal; Electroacupuncture; Glial Fibrillary Acidic Protein; Glucosides; Humans; Male; Nestin; Neural Stem Cells; Rats; Rats, Sprague-Dawley | 2015 |
Salidroside suppresses inflammation in a D-galactose-induced rat model of Alzheimer's disease via SIRT1/NF-κB pathway.
Topics: Alzheimer Disease; Animals; Avoidance Learning; Brain; Cognition; Disease Models, Animal; Galactose; Glucosides; Inflammation; Male; Memory; NF-kappa B; Phenols; Rats; Rats, Sprague-Dawley; Signal Transduction; Sirtuin 1 | 2016 |
Amplexicaule A exerts anti-tumor effects by inducing apoptosis in human breast cancer.
Topics: Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Female; Flavonoids; Glucosides; Humans; MCF-7 Cells; Mice; Plant Extracts; Polygonum; Random Allocation; Xenograft Model Antitumor Assays | 2016 |
Effect of Corilagin on the miR-21/smad7/ERK signaling pathway in a schistosomiasis-induced hepatic fibrosis mouse model.
Topics: Animals; Connective Tissue Growth Factor; Disease Models, Animal; Female; Glucosides; Humans; Hydrolyzable Tannins; Liver Cirrhosis; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; MicroRNAs; Protein Serine-Threonine Kinases; Quality of Life; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Schistosoma japonicum; Schistosomiasis japonica; Smad7 Protein | 2016 |
[Intervention of Yangfei Ziyin Decoction on Sjogren's Syndrome Model Mice].
Topics: Animals; Aquaporin 5; Disease Models, Animal; Drugs, Chinese Herbal; Glucosides; Interleukin-6; Mice; Paeonia; Salivation; Sjogren's Syndrome; Submandibular Gland; Tumor Necrosis Factor-alpha | 2016 |
Salidroside, a Bioactive Compound of Rhodiola Rosea, Ameliorates Memory and Emotional Behavior in Adult Mice.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Conditioning, Psychological; Depressive Disorder; Disease Models, Animal; Drug Evaluation, Preclinical; Exploratory Behavior; Fear; Female; Freezing Reaction, Cataleptic; Glucosides; Male; Maze Learning; Memory; Mice, Inbred C57BL; Motor Activity; Nootropic Agents; Phenols; Phytotherapy; Plant Extracts; Rhodiola | 2016 |
Gastrodin suppresses BACE1 expression under oxidative stress condition via inhibition of the PKR/eIF2α pathway in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Benzyl Alcohols; Cell Line, Tumor; Disease Models, Animal; eIF-2 Kinase; Glucosides; Hippocampus; Humans; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxidative Stress; Signal Transduction; Spatial Memory | 2016 |
Geraniin ameliorates cisplatin-induced nephrotoxicity in mice.
Topics: Animals; Cisplatin; Disease Models, Animal; Glucosides; Hydrolyzable Tannins; Kidney; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Renal Insufficiency | 2016 |
Effects and mechanisms of Shaofu-Zhuyu decoction and its major bioactive component for Cold - Stagnation and Blood - Stasis primary dysmenorrhea rats.
Topics: Animals; Cells, Cultured; Cytokines; Disease Models, Animal; Drugs, Chinese Herbal; Dysmenorrhea; Female; Glucosides; Humans; Leukocytes, Mononuclear; Metabolomics; Mitogen-Activated Protein Kinases; Monoterpenes; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats, Sprague-Dawley; RNA, Messenger | 2016 |
Polydatin ameliorates injury to the small intestine induced by hemorrhagic shock via SIRT3 activation-mediated mitochondrial protection.
Topics: Animals; Disease Models, Animal; Female; Glucosides; Hydrogen Peroxide; Intestine, Small; Male; Mitochondria; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Shock, Hemorrhagic; Signal Transduction; Sirtuins; Stilbenes; Superoxide Dismutase | 2016 |
Thrombosis recanalization by paeoniflorin through the upregulation of urokinase‑type plasminogen activator via the MAPK signaling pathway.
Topics: Animals; Blood Coagulation; Cell Proliferation; Cell Survival; Disease Models, Animal; Gene Expression Regulation; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Mice; Monoterpenes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Thrombosis; Urokinase-Type Plasminogen Activator | 2016 |
A new co-micronized composite containing palmitoylethanolamide and polydatin shows superior oral efficacy compared to their association in a rat paw model of carrageenan-induced inflammation.
Topics: Active Transport, Cell Nucleus; Administration, Oral; Amides; Animals; Carrageenan; Cell Line, Tumor; Cell Nucleus; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Drug Compounding; Drug Interactions; Edema; Ethanolamines; Gene Expression Regulation, Enzymologic; Glucosides; Hyperalgesia; Inflammation; Male; Neutrophil Infiltration; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase Type II; Palmitic Acids; Proteolysis; Rats; Rats, Sprague-Dawley; Stilbenes; Superoxide Dismutase; Transcription Factor RelA; Tyrosine | 2016 |
Neuroprotective effects of salidroside through PI3K/Akt pathway activation in Alzheimer's disease models.
Topics: Alzheimer Disease; Animals; Disease Models, Animal; Drosophila; Glucosides; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Phenols; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rhodiola; Signal Transduction | 2016 |
Rhodioloside ameliorates depressive behavior via up-regulation of monoaminergic system activity and anti-inflammatory effect in olfactory bulbectomized rats.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Biogenic Monoamines; Depression; Disease Models, Animal; Glucosides; Interleukin-1beta; Interleukin-6; Male; NF-kappa B; Olfactory Bulb; Phenols; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Rhodiola; Signal Transduction | 2016 |
Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice.
Topics: Albuminuria; Animals; Benzhydryl Compounds; Biomarkers; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Drug Administration Schedule; Glucosides; Hepatitis A Virus Cellular Receptor 1; Hypoglycemic Agents; Lipocalin-2; Male; Mice; Treatment Outcome | 2016 |
Cyanidin 3-O-β-glucopyranoside activates peroxisome proliferator-activated receptor-γ and alleviates cognitive impairment in the APP(swe)/PS1(ΔE9) mouse model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Anthocyanins; Apoptosis; Brain; Cell Line; Cognitive Dysfunction; Disease Models, Animal; Female; Glucose; Glucosides; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Transgenic; Microscopy, Electron, Transmission; Neurons; Peptide Fragments; PPAR gamma; Presenilin-1; Protein Aggregation, Pathological; Reactive Oxygen Species; Recombinant Fusion Proteins | 2016 |
Comparative Effect of Quercetin and Quercetin-3-O-β-d-Glucoside on Fibrin Polymers, Blood Clots, and in Rodent Models.
Topics: Acute Disease; Animals; Blood Coagulation; Blood Platelets; Collagen; Disease Models, Animal; Epinephrine; Factor Xa; Fibrin; Fibrinolytic Agents; Flavonoids; Glucosides; Male; Mice; Mice, Inbred ICR; Platelet Activation; Primary Cell Culture; Quercetin; Rats, Sprague-Dawley; Signal Transduction; Thrombin; Thromboembolism | 2016 |
Paeoniflorin ameliorates acute necrotizing pancreatitis and pancreatitis‑induced acute renal injury.
Topics: Acute Kidney Injury; Amylases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Blood Urea Nitrogen; Caspase 3; Creatine; Disease Models, Animal; Glucosides; Lipase; Monoterpenes; NF-kappa B; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Pancreatitis, Acute Necrotizing; Rats; Signal Transduction; Time Factors | 2016 |
Paeoniflorin Promotes Angiogenesis in A Vascular Insufficiency Model of Zebrafish in vivo and in Human Umbilical Vein Endothelial Cells in vitro.
Topics: Angiogenesis Inducing Agents; Animals; Animals, Genetically Modified; Cells, Cultured; Disease Models, Animal; Drugs, Chinese Herbal; Embryo, Nonmammalian; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Monoterpenes; Neovascularization, Physiologic; Phytotherapy; Vascular Diseases; Zebrafish | 2018 |
Pharmacokinetics and pharmacodynamics of glycyrrhetinic acid with Paeoniflorin after transdermal administration in dysmenorrhea model mice.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Drug Synergism; Drugs, Chinese Herbal; Dysmenorrhea; Female; Glucosides; Glycyrrhetinic Acid; Meloxicam; Mice; Monoterpenes; Skin Absorption; Thiazines; Thiazoles; Tissue Distribution; Transdermal Patch | 2016 |
Evaluation of wound healing properties of bioactive aqueous fraction from Moringa oleifera Lam on experimentally induced diabetic animal model.
Topics: Animals; Anti-Bacterial Agents; Apigenin; Diabetes Mellitus, Experimental; Diabetic Foot; Disease Models, Animal; Dose-Response Relationship, Drug; Escherichia coli; Glucosides; Male; Microbial Sensitivity Tests; Moringa oleifera; Niacinamide; Plant Extracts; Pseudomonas aeruginosa; Rats, Wistar; Staphylococcus aureus; Streptozocin; Structure-Activity Relationship; Water; Wound Healing | 2016 |
Salidroside reduces renal cell carcinoma proliferation by inhibiting JAK2/STAT3 signaling.
Topics: Animals; Apoptosis; Carcinoma, Renal Cell; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Glucosides; Humans; Janus Kinase 2; Kidney Neoplasms; Male; Mice; Phenols; Signal Transduction; STAT3 Transcription Factor; Xenograft Model Antitumor Assays | 2016 |
[Effect of polydatin on miR-214 expression and liver function in ApoE-/- mice].
Topics: Animals; Apolipoproteins E; Atherosclerosis; Blood Glucose; Diet, High-Fat; Disease Models, Animal; Drugs, Chinese Herbal; Glucosides; Lipids; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Stilbenes; Superoxide Dismutase | 2016 |
Cardiac stem cell transplantation with 2,3,5,4'-tetrahydroxystilbehe-2-O-β-d-glucoside improves cardiac function in rat myocardial infarction model.
Topics: Animals; Disease Models, Animal; Glucosides; Heart Rate; Male; Myocardial Infarction; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Stem Cell Transplantation; Stilbenes | 2016 |
Paeoniflorin alleviates non-alcoholic steatohepatitis in rats: Involvement with the ROCK/NF-κB pathway.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Cholesterol; Diet; Disease Models, Animal; Glucosides; Humans; Male; Monoterpenes; NF-kappa B; Non-alcoholic Fatty Liver Disease; Paeonia; Rats; Rats, Sprague-Dawley; Rhizome; rho-Associated Kinases; Signal Transduction; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2016 |
Polydatin possesses notable anti‑osteoporotic activity via regulation of OPG, RANKL and β‑catenin.
Topics: Alkaline Phosphatase; Animals; beta Catenin; Biomarkers; Body Weight; Bone and Bones; Calcium; Cell Line; Disease Models, Animal; Female; Gene Expression Regulation; Glucosides; Mice; Osteoporosis; Osteoprotegerin; Ovariectomy; RANK Ligand; Stilbenes | 2016 |
Tofogliflozin, a selective inhibitor of sodium-glucose cotransporter 2, suppresses renal damage in KKAy/Ta mice, obese and type 2 diabetic animals.
Topics: Acetylglucosaminidase; Albuminuria; Animals; Benzhydryl Compounds; Biomarkers; Blood Glucose; Cytoprotection; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Glucosides; Hypoglycemic Agents; Kidney; Male; Mice, Inbred C57BL; Obesity; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2016 |
Gastrodin reversed the traumatic stress-induced depressed-like symptoms in rats.
Topics: Animals; Antidepressive Agents; Benzyl Alcohols; Brain-Derived Neurotrophic Factor; Depression; Depressive Disorder; Disease Models, Animal; Gastrodia; Glucosides; Hippocampus; Locus Coeruleus; Male; Neuropeptide Y; Norepinephrine; Phytotherapy; Plant Extracts; Rats, Sprague-Dawley; Stress Disorders, Post-Traumatic; Swimming; Tyrosine 3-Monooxygenase | 2016 |
Corilagin ameliorates schistosomiasis hepatic fibrosis through regulating IL-13 associated signal pathway in vitro and in vivo.
Topics: Animals; Blotting, Western; Cell Line; Collagen; Disease Models, Animal; Gastrointestinal Agents; Gene Expression Profiling; Glucosides; Histocytochemistry; Hydrolyzable Tannins; Immunohistochemistry; Interleukin-13; Interleukin-13 Receptor alpha1 Subunit; Janus Kinase 1; Liver; Liver Cirrhosis; Mice, Inbred BALB C; Microscopy; Models, Biological; Rats; Real-Time Polymerase Chain Reaction; Schistosomiasis; Signal Transduction; Treatment Outcome | 2016 |
Barley Sprouts Extract Attenuates Alcoholic Fatty Liver Injury in Mice by Reducing Inflammatory Response.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apigenin; Biomarkers; Cell Survival; Dietary Supplements; Disease Models, Animal; Fatty Liver, Alcoholic; Glucosides; Hordeum; Inflammation Mediators; Lipopolysaccharides; Liver; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Plant Extracts; RAW 264.7 Cells; Seedlings | 2016 |
Total Glucosides of Paeony Promote Intestinal Motility in Slow Transit Constipation Rats through Amelioration of Interstitial Cells of Cajal.
Topics: Animals; Constipation; Disease Models, Animal; Female; Gastrointestinal Motility; Glucosides; Interstitial Cells of Cajal; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase; Paeonia; Prospective Studies; Proto-Oncogene Proteins c-kit; Rats; Rats, Wistar; Stem Cell Factor; Substance P; Vasoactive Intestinal Peptide | 2016 |
Luteolin-7-glucoside inhibits IL-22/STAT3 pathway, reducing proliferation, acanthosis, and inflammation in keratinocytes and in mouse psoriatic model.
Topics: Acanthosis Nigricans; Aminoquinolines; Animals; Cell Differentiation; Cell Nucleus; Cell Proliferation; Cells, Cultured; Cellular Senescence; Disease Models, Animal; Glucosides; Humans; Imiquimod; Immunohistochemistry; Inflammation; Interleukin-22; Interleukins; Keratinocytes; Lipids; Luteolin; Mice, Inbred C57BL; Oxidation-Reduction; Phenotype; Protein Transport; Psoriasis; Signal Transduction; STAT3 Transcription Factor | 2016 |
Procyanidin Promotes Translocation of Glucose Transporter 4 in Muscle of Mice through Activation of Insulin and AMPK Signaling Pathways.
Topics: AMP-Activated Protein Kinases; Animals; Anthocyanins; Biflavonoids; Catechin; Disease Models, Animal; Glucose; Glucose Transporter Type 4; Glucosides; Humans; Hyperglycemia; Insulin; Mice; Muscle, Skeletal; Proanthocyanidins; Signal Transduction | 2016 |
Polydatin protects cardiomyocytes against myocardial infarction injury by activating Sirt3.
Topics: Animals; Apoptosis; Disease Models, Animal; Glucosides; Mice; Mice, Knockout; Mitochondria, Heart; Myocardial Infarction; Myocytes, Cardiac; Organelle Biogenesis; Sirtuin 3; Stilbenes | 2017 |
Pharmacokinetic Comparison of Scutellarin and Paeoniflorin in Sham-Operated and Middle Cerebral Artery Occlusion Ischemia and Reperfusion Injury Rats after Intravenous Administration of Xin-Shao Formula.
Topics: Animals; Apigenin; Disease Models, Animal; Glucosides; Glucuronates; Infarction, Middle Cerebral Artery; Male; Medicine, Chinese Traditional; Monoterpenes; Plant Extracts; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stroke | 2016 |
Acteoside Binds to Caspase-3 and Exerts Neuroprotection in the Rotenone Rat Model of Parkinson's Disease.
Topics: alpha-Synuclein; Animals; Caspase 3; Disease Models, Animal; Glucosides; Humans; Microtubule-Associated Proteins; Molecular Dynamics Simulation; Parkinson Disease; Phenols; Protein Binding; Rats; Rats, Sprague-Dawley; Rotenone | 2016 |
Gastrodin Reduces the Severity of Status Epilepticus in the Rat Pilocarpine Model of Temporal Lobe Epilepsy by Inhibiting Nav1.6 Sodium Currents.
Topics: Animals; Benzyl Alcohols; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Temporal Lobe; Glucosides; Male; NAV1.6 Voltage-Gated Sodium Channel; Pilocarpine; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Sodium Channel Blockers; Status Epilepticus | 2017 |
Gastrodin ameliorates subacute phase cerebral ischemia‑reperfusion injury by inhibiting inflammation and apoptosis in rats.
Topics: Animals; Apoptosis; Benzyl Alcohols; Brain Ischemia; Caspase 3; Cyclooxygenase 2; Disease Models, Animal; Drugs, Chinese Herbal; Gene Expression Regulation; Glucosides; Humans; Inflammation; Interleukin-1beta; Nitric Oxide Synthase Type II; Rats; Reperfusion Injury | 2016 |
Effect of Sodium-Glucose Co-Transporter 2 Inhibitor, Dapagliflozin, on Renal Renin-Angiotensin System in an Animal Model of Type 2 Diabetes.
Topics: Aldosterone; Animals; Benzhydryl Compounds; Chymosin; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Glucosides; Hyperglycemia; Kidney; Lipid Peroxidation; Male; Rats, Inbred OLETF; Renin-Angiotensin System; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2016 |
Effect of total peony glucoside pretreatment on NF-κB and ICAM-1 expression in myocardial tissue of rat with myocardial ischemia-reperfusion injury.
Topics: Animals; Disease Models, Animal; Glucosides; Intercellular Adhesion Molecule-1; Interleukin-6; Interleukin-8; Male; Myocardial Reperfusion Injury; Myocardium; NF-kappa B; Paeonia; Rats, Sprague-Dawley; RNA, Messenger | 2016 |
[Effect and mechanism of traditional Chinese herbs against Aβ expression in brain tissues of mice with Alzheimer's disease].
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Benzyl Alcohols; Brain; Disease Models, Animal; Glucosides; Hippocampus; Memory; Mice; Mice, Transgenic; Monoterpenes; Plaque, Amyloid; Random Allocation; Saponins; Triterpenes | 2016 |
Empagliflozin lessened cardiac injury and reduced visceral adipocyte hypertrophy in prediabetic rats with metabolic syndrome.
Topics: Adipocytes, White; Adiposity; Animals; Benzhydryl Compounds; Biomarkers; Cardiomegaly; Disease Models, Animal; Diuresis; Glucosides; Hemodynamics; Hypertrophy; Hypoglycemic Agents; Intra-Abdominal Fat; Male; Metabolic Syndrome; Oxidative Stress; Prediabetic State; Rats, Inbred SHR; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Time Factors; Water-Electrolyte Balance; Weight Gain | 2016 |
Effective treatment of polydatin weakens the symptoms of collagen-induced arthritis in mice through its anti-oxidative and anti-inflammatory effects and the activation of MMP-9.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arthritis, Experimental; Arthritis, Rheumatoid; bcl-2-Associated X Protein; Biomarkers; Caspase 3; Caspase 9; Disease Models, Animal; Glucosides; Glutathione; Male; Malondialdehyde; Matrix Metalloproteinase 9; Mice; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Stilbenes; Superoxide Dismutase | 2016 |
Neuroprotective effects of polydatin against mitochondrial-dependent apoptosis in the rat cerebral cortex following ischemia/reperfusion injury.
Topics: Adenosine Triphosphate; Animals; Apoptosis; bcl-2-Associated X Protein; Biomarkers; Brain Ischemia; Cerebral Cortex; Cytochromes c; Disease Models, Animal; Glucosides; Male; Membrane Potential, Mitochondrial; Mitochondria; Neurons; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; Stilbenes | 2016 |
Mechanism of Corilagin interference with IL-13/STAT6 signaling pathways in hepatic alternative activation macrophages in schistosomiasis-induced liver fibrosis in mouse model.
Topics: Animals; Disease Models, Animal; Gene Expression Regulation; Glucosides; Hydrolyzable Tannins; Interleukin-13; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Liver; Liver Cirrhosis; Macrophage Activation; Macrophages; Male; Mice; Schistosomiasis; Signal Transduction; STAT6 Transcription Factor | 2016 |
Gastrodin Attenuates Pentylenetetrazole-Induced Seizures by Modulating the Mitogen-Activated Protein Kinase-Associated Inflammatory Responses in Mice.
Topics: Animals; Anti-Inflammatory Agents; Benzyl Alcohols; Convulsants; CREB-Binding Protein; Disease Models, Animal; Glucosides; Inflammation; Interleukin-10; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-kappa B; Pentylenetetrazole; Seizures; Tumor Necrosis Factor-alpha | 2017 |
Salidroside accelerates fracture healing through cell-autonomous and non-autonomous effects on osteoblasts.
Topics: Animals; Calcification, Physiologic; Cell Cycle; Cell Differentiation; Cell Line; Cell Proliferation; Cell Survival; Core Binding Factor Alpha 1 Subunit; Disease Models, Animal; Fracture Healing; Glucosides; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Osteoblasts; Osteogenesis; Phenols; Platelet Endothelial Cell Adhesion Molecule-1; Rats, Sprague-Dawley; Signal Transduction; Sp7 Transcription Factor; Transcription Factors; Transcriptional Activation; Vascular Endothelial Growth Factor A | 2017 |
Inhibition of Hypoxia-Induced Retinal Angiogenesis by Specnuezhenide, an Effective Constituent of Ligustrum lucidum Ait., through Suppression of the HIF-1α/VEGF Signaling Pathway.
Topics: Angiogenesis Inhibitors; Animals; Cell Hypoxia; Cell Line; Cobalt; Diabetic Retinopathy; Disease Models, Animal; Epithelial Cells; Gene Expression Regulation; Glucosides; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Inducible Factor-Proline Dioxygenases; Indazoles; Ligustrum; Plant Extracts; Pyrans; Rats; Rats, Sprague-Dawley; Retinal Neovascularization; Retinal Pigment Epithelium; Signal Transduction; Vascular Endothelial Growth Factor A | 2016 |
Paeoniflorin ameliorates interferon-alpha-induced neuroinflammation and depressive-like behaviors in mice.
Topics: Amygdala; Animals; Anti-Inflammatory Agents; Antidepressive Agents; Astrocytes; Behavior, Animal; Brain; Cytokines; Depression; Disease Models, Animal; Encephalitis; Food Preferences; Glucosides; Hippocampus; Inflammation Mediators; Interferon alpha-2; Interferon-alpha; Male; Mice, Inbred C57BL; Microglia; Monoterpenes; Motor Activity; Prefrontal Cortex; Recombinant Proteins; Swimming; Time Factors | 2017 |
The Sodium-Glucose Cotransporter 2 Inhibitor Dapagliflozin Prevents Cardiomyopathy in a Diabetic Lipodystrophic Mouse Model.
Topics: Animals; Benzhydryl Compounds; Blood Glucose; Cardiomyopathy, Hypertrophic; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Disease Models, Animal; Echocardiography; Fluorodeoxyglucose F18; Glucosides; GTP-Binding Protein gamma Subunits; Heart; Heterotrimeric GTP-Binding Proteins; Hyperglycemia; Hypoglycemic Agents; Lipodystrophy; Magnetic Resonance Imaging; Mice; Mice, Knockout; Myocardium; Pioglitazone; Positron-Emission Tomography; Radiopharmaceuticals; Sodium-Glucose Transporter 2 Inhibitors; Thiazolidinediones; Ventricular Dysfunction, Left; Ventricular Function | 2017 |
Maysin and Its Flavonoid Derivative from Centipedegrass Attenuates Amyloid Plaques by Inducting Humoral Immune Response with Th2 Skewed Cytokine Response in the Tg (APPswe, PS1dE9) Alzheimer's Mouse Model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antibodies; Brain; Cytokines; Disease Models, Animal; Flavonoids; Glucosides; Liver; Male; Mice; Mice, Transgenic; Peptide Fragments; Plant Extracts; Plaque, Amyloid; Th2 Cells | 2017 |
Sodium glucose transporter 2 (SGLT2) inhibition with empagliflozin improves cardiac diastolic function in a female rodent model of diabetes.
Topics: Animals; Benzhydryl Compounds; Blood Pressure; Diabetes Mellitus, Type 2; Diastole; Disease Models, Animal; Female; Glucosides; Glycemic Index; Mice; Mice, Inbred C57BL; Mice, Transgenic; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Ventricular Function, Left | 2017 |
Inhibition of PHD3 by salidroside promotes neovascularization through cell-cell communications mediated by muscle-secreted angiogenic factors.
Topics: Angiogenesis Inducing Agents; Animals; Cell Communication; Cell Line; Disease Models, Animal; Endothelial Cells; Glucosides; Hindlimb; Humans; Injections, Intramuscular; Ischemia; Mice, Inbred BALB C; Muscle Cells; Neovascularization, Physiologic; Phenols; Procollagen-Proline Dioxygenase | 2017 |
Beneficial effects of paeoniflorin on non-alcoholic fatty liver disease induced by high-fat diet in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Cytochrome P-450 CYP2E1; Diet, High-Fat; Disease Models, Animal; Glucosides; Insulin Resistance; Lipid Metabolism; Lipids; Liver; Male; Monoterpenes; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Rats; Reactive Oxygen Species; Signal Transduction | 2017 |
Remogliflozin etabonate, in a novel category of selective low-affinity sodium glucose cotransporter (SGLT2) inhibitors, exhibits antidiabetic efficacy in rodent models.
Topics: Animals; Chlorocebus aethiops; COS Cells; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glucose Tolerance Test; Glucosides; Glycosuria; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Pyrazoles; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2008 |
Antinociceptive activity of Buddleja globosa (matico) in several models of pain.
Topics: Administration, Cutaneous; Administration, Oral; Analgesics; Animals; Buddleja; Chile; Disease Models, Animal; Dose-Response Relationship, Drug; Glucosides; Ibuprofen; Luteolin; Male; Medicine, Traditional; Mice; Pain; Pain Measurement; Phenols; Plant Extracts; Plant Leaves; Seasons | 2008 |
Antidepressant-like effect of liquiritin from Glycyrrhiza uralensis in chronic variable stress induced depression model rats.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Exploratory Behavior; Flavanones; Food Preferences; Glucosides; Glycyrrhiza uralensis; Male; Malondialdehyde; Phytotherapy; Plant Extracts; Random Allocation; Rats; Rats, Sprague-Dawley; Stress, Psychological; Superoxide Dismutase; Swimming; Time Factors | 2008 |
Effects of amburoside A and isokaempferide, polyphenols from Amburana cearensis, on rodent inflammatory processes and myeloperoxidase activity in human neutrophils.
Topics: Animals; Anti-Inflammatory Agents; Brazil; Disease Models, Animal; Dose-Response Relationship, Drug; Fabaceae; Flavonoids; Glucosides; Humans; Inflammation; Inflammation Mediators; Male; Medicine, Traditional; Mice; Neutrophils; Peroxidase; Phenols; Plant Bark; Plant Extracts; Polyphenols; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2009 |
Anti-inflammatory phenylpropanoid glycosides from Clerodendron trichotomum leaves.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Biphenyl Compounds; Capillary Permeability; Carrageenan; Catechols; Cell Line; Clerodendrum; Dinoprostone; Disaccharides; Disease Models, Animal; Dose-Response Relationship, Drug; Free Radical Scavengers; Glucosides; Humans; Inflammation; Magnetic Resonance Spectroscopy; Mast Cells; Mice; Molecular Structure; Phenols; Picrates; Plant Leaves; Rats; Thiobarbituric Acid Reactive Substances | 2009 |
Radiolabeled arginine-glycine-aspartic acid peptides to image angiogenesis in swine model of hibernating myocardium.
Topics: Animals; Capillaries; Coronary Angiography; Coronary Circulation; Coronary Stenosis; Disease Models, Animal; Echocardiography; Fibrosis; Gene Transfer Techniques; Genetic Therapy; Glucosides; Humans; Integrin alphaVbeta3; Male; Myocardium; Neovascularization, Physiologic; Oligopeptides; Radiopharmaceuticals; Swine; Time Factors; Tomography, Emission-Computed, Single-Photon; Vascular Endothelial Growth Factor A | 2008 |
Dissection of the role of paeoniflorin in the traditional Chinese medicinal formula Si-Ni-San against contact dermatitis in mice.
Topics: Animals; Benzoates; Blotting, Western; Bridged-Ring Compounds; Cell Line; Cyclooxygenase 2; Dermatitis, Contact; Disease Models, Animal; Drugs, Chinese Herbal; Female; Glucosides; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Monoterpenes; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha | 2009 |
Effects of verbascoside biotechnologically produced by Syringa vulgaris plant cell cultures in a rodent model of colitis.
Topics: Animals; Antioxidants; Body Weight; Cells, Cultured; Colitis; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Precursors; Gelatinases; Glucosides; Male; Matrix Metalloproteinase 9; Peroxidase; Phenols; Rats; Rats, Sprague-Dawley; Syringa; Thiobarbituric Acid Reactive Substances; Transcription Factor RelA | 2009 |
Effect of cornuside on experimental sepsis.
Topics: Animals; Anti-Bacterial Agents; Colony Count, Microbial; Cornus; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Drug Therapy, Combination; Endotoxins; Fruit; Glucosides; Imipenem; Immunologic Factors; Inflammation Mediators; Macrophages; Male; Myeloid Cells; Nitric Oxide; Peroxidase; Phytotherapy; Plant Extracts; Pyrans; Random Allocation; Rats; Rats, Sprague-Dawley; Sepsis; Up-Regulation | 2009 |
Equivocal colonic carcinogenicity of Aloe arborescens Miller var. natalensis berger at high-dose level in a Wistar Hannover rat 2-y study.
Topics: Aloe; Animals; Colonic Neoplasms; Diarrhea; Disease Models, Animal; Emodin; Female; Glucosides; Male; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Survival Rate | 2009 |
Effects of 2,3,4',5-tetrahydroxystilbene 2-O-beta-D-glucoside on vascular endothelial dysfunction in atherogenic-diet rats.
Topics: Animals; Aorta; Atherosclerosis; Disease Models, Animal; Drugs, Chinese Herbal; Endothelium, Vascular; Glucosides; Male; Microscopy, Electron, Transmission; Nitrates; Nitric Oxide Synthase; Nitrites; Polygonum; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stilbenes | 2009 |
Two new flavonol glycosides from Epimedium koreanum Nakai.
Topics: Alkaline Phosphatase; Animals; Disease Models, Animal; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Epimedium; Flavonoids; Glucosides; Mice; Molecular Structure; Plants, Medicinal; Rats | 2009 |
Catalpol ameliorates beta amyloid-induced degeneration of cholinergic neurons by elevating brain-derived neurotrophic factors.
Topics: Amyloid beta-Peptides; Animals; Brain; Brain-Derived Neurotrophic Factor; Cells, Cultured; Choline O-Acetyltransferase; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glucosides; Iridoid Glucosides; Iridoids; Learning; Memory; Mice; Mice, Inbred ICR; Neurites; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic | 2009 |
Antiasthmatic activity of luteolin-7-O-glucoside from Ailanthus altissima through the downregulation of T helper 2 cytokine expression and inhibition of prostaglandin E2 production in an ovalbumin-induced asthma model.
Topics: Ailanthus; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Cytokines; Dinoprostone; Disease Models, Animal; Down-Regulation; Female; Glucosides; Luteolin; Mice; Mice, Inbred BALB C; Ovalbumin; Th2 Cells | 2009 |
TJN-259 improves mesangial lesions in experimental immunoglobulin A nephropathy in ddY mice.
Topics: Animals; Anti-Inflammatory Agents; Cattle; Collagen Type IV; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Glomerular Mesangium; Glomerulonephritis, IGA; Glucosides; Immunoglobulin A; Kidney; Male; Mice; Mice, Inbred Strains; Phenols; Plant Extracts; Pyridines; Sclerosis; Serum Albumin; Stachys; Transforming Growth Factor beta1 | 2009 |
Hepatoprotective effects of salidroside on fulminant hepatic failure induced by D-galactosamine and lipopolysaccharide in mice.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Caspase 3; Disease Models, Animal; Dose-Response Relationship, Drug; Galactosamine; Glucosides; Hypoxia-Inducible Factor 1, alpha Subunit; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Oxidative Stress; Phenols; Tumor Necrosis Factor-alpha | 2009 |
Anti-HIV-1 and anti-inflammatory lupanes from the leaves, twigs, and resin of Garcinia hanburyi.
Topics: Animals; Anti-Inflammatory Agents; Antiviral Agents; Disease Models, Animal; Edema; Garcinia; Giant Cells; Glucosides; HIV-1; Inflammation; Inhibitory Concentration 50; Molecular Structure; Phytotherapy; Plant Extracts; Plant Leaves; Plant Stems; Resins, Plant; RNA-Directed DNA Polymerase; Stigmasterol; Triterpenes; X-Ray Diffraction | 2010 |
Oral supplementation of catalpol ameliorates diabetic encephalopathy in rats.
Topics: Administration, Oral; Animals; Behavior, Animal; Blood Glucose; Body Weight; Catalase; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Glucosides; Glutathione Peroxidase; In Situ Nick-End Labeling; Iridoid Glucosides; Iridoids; Lipid Peroxidation; Male; Malondialdehyde; Maze Learning; Nerve Growth Factor; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Time Factors | 2010 |
Protective effect of tetrahydroxystilbene glucoside on cardiotoxicity induced by doxorubicin in vitro and in vivo.
Topics: Animals; Animals, Newborn; Antibiotics, Antineoplastic; Apoptosis; Calcium; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Glucosides; Heart Diseases; Male; Mice; Myocytes, Cardiac; Rats; Reactive Oxygen Species; Signal Transduction; Stilbenes | 2009 |
Catalpol attenuates MPTP induced neuronal degeneration of nigral-striatal dopaminergic pathway in mice through elevating glial cell derived neurotrophic factor in striatum.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Cells, Cultured; Chronic Disease; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Glial Cell Line-Derived Neurotrophic Factor; Glucosides; Iridoid Glucosides; Iridoids; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Motor Activity; Nerve Degeneration; Neural Pathways; Neurons; Neuroprotective Agents; Probenecid; Substantia Nigra | 2010 |
The anti-inflammatory effect of paeoniflorin on cerebral infarction induced by ischemia-reperfusion injury in Sprague-Dawley rats.
Topics: Animals; Anti-Inflammatory Agents; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Apoptosis; Benzoates; Brain; Bridged-Ring Compounds; Cerebral Infarction; Disease Models, Animal; Glucosides; Intercellular Adhesion Molecule-1; Interleukin-1beta; Monoterpenes; Nervous System Diseases; Paeonia; Peroxidase; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factor-alpha | 2010 |
[Study of geniposide-acid on anti-inflammatory action for adjuvant-induced arthritis rats and mechanism of synoviocyte apoptosis in vitro].
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Arthritis, Experimental; Cytokines; Disease Models, Animal; Freund's Adjuvant; Glucosides; Humans; Iridoid Glucosides; Iridoids; Male; Random Allocation; Rats; Rats, Wistar; Synovial Fluid | 2009 |
Verbascoside isolated from Tectona grandis mediates gastric protection in rats via inhibiting proton pump activity.
Topics: Animals; Anti-Ulcer Agents; Cold Temperature; Dinoprostone; Disease Models, Animal; Female; Gastric Acid; Gastric Mucosa; Gastrins; Glucosides; Male; Mucins; Pepsin A; Phenols; Phytotherapy; Plant Extracts; Plant Leaves; Proton Pump Inhibitors; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Stomach; Stomach Ulcer; Verbenaceae | 2010 |
Prophylactic treatment with Hypoxis hemerocallidea corm (African potato) methanolic extract ameliorates Brachyspira hyodysenteriae-induced murine typhlocolitis.
Topics: Africa, Southern; Alkynes; Animals; Anti-Inflammatory Agents; Brachyspira hyodysenteriae; Cell Proliferation; Disease Models, Animal; Down-Regulation; Glucosides; Gram-Negative Bacterial Infections; Hypoxis; Inflammatory Bowel Diseases; Intestinal Mucosa; Mice; Mice, Inbred C3H; Neutrophils; NF-kappa B; Peroxidase; Phytotherapy; Plant Extracts; Plants, Medicinal; RNA, Messenger; Signal Transduction; Transcription Factor RelA | 2010 |
Neuroprotective efficacy and therapeutic window of Forsythoside B: in a rat model of cerebral ischemia and reperfusion injury.
Topics: Animals; Anti-Inflammatory Agents; Antigens, Nuclear; Brain Infarction; Brain Ischemia; Caffeic Acids; Disease Models, Animal; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Glucosides; Glycosides; Leukocytes; Male; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; NF-kappa B; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2010 |
Anti-inflammation effects of picroside 2 in cerebral ischemic injury rats.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Brain; Brain Ischemia; Caffeic Acids; Cinnamates; Disease Models, Animal; Encephalitis; Female; Glucosides; Infarction, Middle Cerebral Artery; Iridoid Glucosides; Lactates; Neuropsychological Tests; NF-kappa B; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Toll-Like Receptor 4; Treatment Outcome; Tumor Necrosis Factor-alpha | 2010 |
Bioassay-guided isolation of anti-inflammatory, antinociceptive and wound healer glycosides from the flowers of Verbascum mucronatum Lam.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Disease Models, Animal; Edema; Flowers; Glucosides; Iridoid Glycosides; Male; Mice; Molecular Structure; Phenols; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Skin; Triterpenes; Verbascum; Wound Healing | 2011 |
Quercetin-6-C-β-D-glucopyranoside isolated from Ulmus wallichiana planchon is more potent than quercetin in inhibiting osteoclastogenesis and mitigating ovariectomy-induced bone loss in rats.
Topics: Animals; Bone and Bones; Bone Density; Bone Marrow; Cells, Cultured; Collagen Type I; Disease Models, Animal; Female; Glucosides; Humans; Osteocalcin; Osteoclasts; Osteogenesis; Osteoporosis, Postmenopausal; Plant Extracts; Quercetin; Rats; Ulmus; Uterus | 2011 |
Isolation of anxiolytic principle from ethanolic root extract of Cardiospermum halicacabum.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Diazepam; Disease Models, Animal; Glucosides; Light; Male; Maze Learning; Mice; Phytotherapy; Plant Extracts; Plant Roots; Sapindaceae | 2011 |
Protective roles of cornuside in acute myocardial ischemia and reperfusion injury in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cornus; Disease Models, Animal; Drugs, Chinese Herbal; Glucosides; Heart; Hemodynamics; Inflammation; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Phytotherapy; Plants, Medicinal; Pyrans; Rats; Rats, Sprague-Dawley | 2011 |
Efficacy of treatment with verbascoside, biotechnologically produced by Syringa vulgaris plant cell cultures in an experimental mice model of spinal cord trauma.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cell Culture Techniques; Chromatography, High Pressure Liquid; Disease Models, Animal; Glucosides; Immunohistochemistry; In Situ Nick-End Labeling; Injections, Intraperitoneal; Interleukin-1beta; Male; Mice; Mice, Inbred Strains; Motor Activity; Nitric Oxide Synthase Type II; Phenols; Plant Extracts; Poly Adenosine Diphosphate Ribose; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Spinal Cord; Spinal Cord Injuries; Syringa; Tumor Necrosis Factor-alpha; Tyrosine | 2010 |
Effect of salidroside, active principle of Rhodiola rosea extract, on binge eating.
Topics: Analysis of Variance; Animals; Bulimia; Disease Models, Animal; Feeding Behavior; Female; Glucosides; Phenols; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Rhodiola; Stress, Psychological | 2010 |
Pep-1 peptide-conjugated elastic liposomal formulation of taxifolin glycoside for the treatment of atopic dermatitis in NC/Nga mice.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cysteamine; Dermatitis, Atopic; Disease Models, Animal; Drug Carriers; Elasticity; Excipients; Glucosides; Liposomes; Male; Mice; Mice, Inbred ICR; Peptides; Permeability; Quercetin; Skin Absorption | 2010 |
Paeoniflorin: a monomer from traditional Chinese medical herb ameliorates Schistosoma japonicum egg-induced hepatic fibrosis in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Bridged-Ring Compounds; Collagen Type I; Collagen Type III; Disease Models, Animal; Drugs, Chinese Herbal; Female; Glucosides; Hydroxyproline; Interleukin-13; Interleukin-13 Receptor alpha2 Subunit; Liver; Liver Cirrhosis; Mice; Mice, Inbred BALB C; Monoterpenes; Paeonia; Plant Roots; Random Allocation; Schistosomiasis japonica | 2009 |
Polydatin ameliorates DSS-induced colitis in mice through inhibition of nuclear factor-kappaB activation.
Topics: Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Glucosides; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Peroxidase; Pilot Projects; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes; Tumor Necrosis Factor-alpha | 2011 |
Validated LC-MS/MS methods for the determination of dapagliflozin, a sodium-glucose co-transporter 2 inhibitor in normal and ZDF rat plasma.
Topics: Acetonitriles; Animals; Benzhydryl Compounds; Chromatography, High Pressure Liquid; Disease Models, Animal; Enzyme Inhibitors; Glucosides; Mass Spectrometry; Rats; Rats, Zucker; Reproducibility of Results; Sensitivity and Specificity; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Solid Phase Extraction; Water | 2010 |
Neuroprotective effect of liquiritin against focal cerebral ischemia/reperfusion in mice via its antioxidant and antiapoptosis properties.
Topics: Animals; Antioxidants; Apoptosis; Brain Ischemia; Disease Models, Animal; Flavanones; Glucosides; Glycyrrhiza; Male; Mice; Mice, Inbred ICR; Molecular Structure; Neuroprotective Agents; Oxidation-Reduction; Rats; Superoxide Dismutase | 2010 |
[Effects of tetrahydroxystilbene glucoside on nerve growth factor and growth associated protein in rats after cerebral ischemia-reperfusion].
Topics: Animals; Brain Ischemia; Cerebral Cortex; Disease Models, Animal; GAP-43 Protein; Glucosides; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Nerve Growth Factor; Neuroprotective Agents; Polygonaceae; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stilbenes | 2010 |
Salidroside attenuates apoptosis in ischemic cardiomyocytes: a mechanism through a mitochondria-dependent pathway.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cells, Cultured; Disease Models, Animal; Glucosides; Male; Membrane Potentials; Mitochondria, Heart; Myocardial Ischemia; Myocytes, Cardiac; Phenols; Phosphorylation; Phytotherapy; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Rhodiola; Up-Regulation | 2010 |
Dietary aloin, aloesin, or aloe-gel exerts anti-inflammatory activity in a rat colitis model.
Topics: Aloe; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromones; Colitis; Colon; Diet; Dietary Supplements; Disease Models, Animal; Emodin; Gels; Glucosides; Interleukin-1beta; Leukotriene B4; Male; Peroxidase; Plant Preparations; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2011 |
Hypoglycaemic action of stevioside and а barley and brewer's yeast based preparation in the experimental model on mice.
Topics: Alloxan; Animals; Blood Glucose; Chromium; Diabetes Mellitus, Experimental; Disease Models, Animal; Diterpenes, Kaurane; Epinephrine; Fasting; Female; Glucose; Glucosides; Hordeum; Hyperglycemia; Hypoglycemic Agents; Male; Mice; Mice, Inbred Strains; Plant Extracts; Saccharomyces cerevisiae | 2011 |
[Effect of polydatin on dynamic changes of excitatory amino acids in cerebrospinal fluid of cerebral hemorrhage rats].
Topics: Animals; Aspartic Acid; Cerebral Hemorrhage; Disease Models, Animal; Drugs, Chinese Herbal; Excitatory Amino Acids; Glucosides; Glutamic Acid; Humans; Male; Rats; Rats, Sprague-Dawley; Stilbenes | 2010 |
The effect of Eleutheroside E on behavioral alterations in murine sleep deprivation stress model.
Topics: Animals; Antioxidants; Avoidance Learning; Behavior, Animal; Body Weight; Disease Models, Animal; Dopamine; Glucosides; Glutathione; Hippocampus; Lignans; Locomotion; Male; Malondialdehyde; Maze Learning; Mice; Mice, Inbred ICR; Neurotransmitter Agents; Serotonin; Sleep Deprivation; Stress, Psychological; Time Factors | 2011 |
Antihyperalgesic activity of verbascoside in two models of neuropathic pain.
Topics: Administration, Oral; Analgesics; Animals; Disease Models, Animal; Drugs, Chinese Herbal; Glucosides; Hyperalgesia; Injections, Intraperitoneal; Iodoacetates; Lippia; Male; Neuralgia; Phenols; Phytotherapy; Rats; Rats, Sprague-Dawley; Rotarod Performance Test; Sciatic Nerve | 2011 |
Antifibrosis effects of total glucosides of Danggui-Buxue-Tang in a rat model of bleomycin-induced pulmonary fibrosis.
Topics: Animals; Bleomycin; Collagen Type I; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glucosides; Lung; Male; Phytotherapy; Pulmonary Fibrosis; Random Allocation; Rats; Rats, Wistar; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha; Weight Loss | 2011 |
Effects of verbascoside, biotechnologically purified by Syringa vulgaris plant cell cultures, in a rodent model of periodontitis.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Cells, Cultured; Disease Models, Animal; Gingiva; Glucosides; Inflammation Mediators; Ligation; Male; Molar; Mouth Mucosa; Periodontitis; Phenols; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Syringa | 2011 |
Antinociceptive effect of paeoniflorin via spinal α₂-adrenoceptor activation in diabetic mice.
Topics: Analgesics; Animals; Animals, Outbred Strains; Benzoates; Bridged-Ring Compounds; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Glucosides; Male; Mice; Monoterpenes; Nociception; Norepinephrine; Receptors, Adrenergic, alpha-2 | 2011 |
Seco-eremophiladiolides and eremophilane glucosides from Pittocaulon velatum.
Topics: Animals; Anti-Inflammatory Agents; Asteraceae; Disease Models, Animal; Edema; Flavonoids; Glucosides; Mexico; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Sesquiterpenes; Tetradecanoylphorbol Acetate | 2011 |
Cyanidin-3-glucoside ameliorates ethanol neurotoxicity in the developing brain.
Topics: Alcohol-Induced Disorders, Nervous System; Animals; Anthocyanins; Brain; Disease Models, Animal; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Glucosides; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Pregnancy | 2011 |
Flavonoids of Enhydra Fluctuans exhibits analgesic and anti-inflammatory activity in different animal models.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Antioxidants; Asteraceae; Disaccharides; Disease Models, Animal; Drug Evaluation, Preclinical; Flavones; Flavonoids; Glucosides; Inflammation; Male; Mice; Pain Measurement; Pain Threshold; Phytotherapy; Plant Components, Aerial; Plant Extracts; Rats; Rats, Wistar | 2011 |
Cardioprotective effect of polydatin against ischemia/reperfusion injury: roles of protein kinase C and mito K(ATP) activation.
Topics: Animals; Antioxidants; Cardiotonic Agents; Creatine Kinase; Disease Models, Animal; Drugs, Chinese Herbal; Enzyme Inhibitors; Fallopia japonica; Glucosides; Injections, Intravenous; KATP Channels; L-Lactate Dehydrogenase; Male; Malondialdehyde; Mitochondria; Myocardial Reperfusion Injury; Oxidative Stress; Phytotherapy; Protein Kinase C; Random Allocation; Rats; Rats, Sprague-Dawley; Signal Transduction; Stilbenes; Superoxide Dismutase | 2011 |
In vivo anti-inflammatory and antioxidant properties of ellagitannin metabolite urolithin A.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Coumarins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Discovery; Drug Evaluation, Preclinical; Edema; Free Radical Scavengers; Glucosides; Glucuronides; Humans; Hydrolyzable Tannins; Lythraceae; Mice; Mice, Inbred ICR; Rats | 2011 |
Formulation and evaluation of in situ gelling systems for intranasal administration of gastrodin.
Topics: Absorption; Acetic Acid; Adhesiveness; Administration, Intranasal; Animals; Anura; Benzyl Alcohols; Chemistry, Pharmaceutical; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Stability; Drugs, Chinese Herbal; Elasticity; Gels; Glucosides; Male; Nasal Mucosa; Pain; Parabens; Permeability; Polysaccharides, Bacterial; Preservatives, Pharmaceutical; Rats; Rats, Sprague-Dawley; Rheology; Sleep; Technology, Pharmaceutical; Temperature; Time Factors; Viscosity; Water | 2011 |
Acute and chronic effects of SGLT2 blockade on glomerular and tubular function in the early diabetic rat.
Topics: Animals; Benzhydryl Compounds; Diabetes Mellitus, Experimental; Disease Models, Animal; Feedback, Physiological; Glomerular Filtration Rate; Glucosides; Homeostasis; Kidney Glomerulus; Kidney Tubules; Male; Rats; Rats, Wistar; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Streptozocin | 2012 |
Neuroprotective effects of Salidroside and its analogue tyrosol galactoside against focal cerebral ischemia in vivo and H2O2-induced neurotoxicity in vitro.
Topics: Animals; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Brain Ischemia; Cell Survival; Cerebral Cortex; Disease Models, Animal; Drug Administration Schedule; Galactosides; Glucosides; Hydrogen Peroxide; Infarction, Middle Cerebral Artery; Male; Neurons; Neuroprotective Agents; Oxidants; Phenols; Phenylethyl Alcohol; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury | 2012 |
[Effects of Tiangou Jiangya capsule on hypertension and hemodynamics in anaesthetized dogs].
Topics: Animals; Antihypertensive Agents; Benzyl Alcohols; Blood Pressure; Disease Models, Animal; Dogs; Drugs, Chinese Herbal; Female; Flavonoids; Furans; Glucosides; Heart Rate; Hemodynamics; Hypertension; Lignans; Male; Oxygen Consumption; Vascular Resistance | 2011 |
[Effects of Tiangou Jiangya capsule on blood pressure in spontaneous hypertensive rat].
Topics: Animals; Antihypertensive Agents; Benzyl Alcohols; Blood Pressure; Disease Models, Animal; Diuresis; Drugs, Chinese Herbal; Flavonoids; Furans; Glucosides; Heart Rate; Hypertension; Lignans; Male; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Ventricular Function, Left | 2011 |
Polydatin protects learning and memory impairments in a rat model of vascular dementia.
Topics: Animals; Catalase; Cells, Cultured; Dementia, Vascular; Disease Models, Animal; Drugs, Chinese Herbal; Fallopia japonica; Glucosides; Hippocampus; Learning; Male; Malondialdehyde; Maze Learning; Memory Disorders; Neurons; Neuroprotective Agents; Protective Agents; Rats; Rats, Sprague-Dawley; Stilbenes; Superoxide Dismutase | 2012 |
Discovery of Ipragliflozin (ASP1941): a novel C-glucoside with benzothiophene structure as a potent and selective sodium glucose co-transporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes mellitus.
Topics: Animals; Blood Glucose; CHO Cells; Cricetinae; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Glucosides; Humans; Hypoglycemic Agents; Inhibitory Concentration 50; Male; Mice; Molecular Structure; Rats; Rats, Sprague-Dawley; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2012 |
Protective effects of salidroside from Rhodiola rosea on LPS-induced acute lung injury in mice.
Topics: Acute Lung Injury; Animals; Cytokines; Disease Models, Animal; Glucosides; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Phenols; Rhodiola | 2012 |
[Treatment of premenstrual syndrome with Chinese medicine formula, baixiangdan capsule: implications for neuron viability and GABA(A) receptor modulation in rat cortex].
Topics: Acetophenones; Administration, Oral; Animals; Benzoates; Bridged-Ring Compounds; Cell Culture Techniques; Cell Proliferation; Cell Survival; Cerebral Cortex; Disease Models, Animal; Drugs, Chinese Herbal; Female; Glucosides; Liver Diseases; Monoterpenes; Neurons; Patch-Clamp Techniques; Premenstrual Syndrome; Qi; Rats; Rats, Wistar; Receptors, GABA-A | 2011 |
Roles of iron acquisition systems in virulence of extraintestinal pathogenic Escherichia coli: salmochelin and aerobactin contribute more to virulence than heme in a chicken infection model.
Topics: Animal Structures; Animals; Chickens; Disease Models, Animal; Enterobactin; Escherichia coli; Escherichia coli Infections; Gene Deletion; Glucosides; Heme; Histocytochemistry; Hydroxamic Acids; Iron; Microscopy; Virulence Factors | 2012 |
Antiepileptic potential of ursolic acid stearoyl glucoside by GABA receptor stimulation.
Topics: Animals; Anticonvulsants; Convulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Epilepsy; Glucosides; Isoniazid; Lantana; Phytotherapy; Plant Extracts; Plant Leaves; Receptors, GABA; Saponins; Seizures; Triterpenes; Ursolic Acid | 2012 |
Evaluation of the in vivo anti-inflammatory and analgesic activity of a highly water-soluble aspirin conjugate.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Glucosides; Hydrolysis; Mice; Molecular Structure; Pain Threshold; Rats; Solubility; Water | 2013 |
Antihypertensive and cardioprotective effects of the Lagenaria siceraria fruit in NG-nitro-L-arginine methyl ester (L-NAME) induced hypertensive rats.
Topics: Animals; Antihypertensive Agents; Antioxidants; Apigenin; Blood Pressure; Cardiotonic Agents; Cholesterol; Chromatography, High Pressure Liquid; Cucurbitaceae; Disease Models, Animal; Flavonoids; Fruit; Glucosides; Hypertension; Inflammation; Luteolin; Male; NG-Nitroarginine Methyl Ester; Plant Extracts; Rats; Rats, Wistar | 2012 |
Identification of brain-targeted bioactive dietary quercetin-3-O-glucuronide as a novel intervention for Alzheimer's disease.
Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anthocyanins; Biological Availability; Brain; Cells, Cultured; Dietary Supplements; Disease Models, Animal; Glucosides; Humans; Male; Mice; Mice, Transgenic; Neuronal Plasticity; Neurons; Neuroprotective Agents; Polyphenols; Protein Multimerization; Quercetin; Rats; Rats, Sprague-Dawley; Signal Transduction; Wine | 2013 |
Purple rice extract and its constituents suppress endoplasmic reticulum stress-induced retinal damage in vitro and in vivo.
Topics: Animals; Anthocyanins; Caspase 3; Cell Death; Cells, Cultured; Disease Models, Animal; Endoplasmic Reticulum Stress; Glucosides; Hydrogen Peroxide; Male; Mice; Oryza; Plant Extracts; Retinal Ganglion Cells; Tunicamycin | 2013 |
[Study on effect and mechanism of salidroside on cognitive ability of Abeta1-40 -induced Alzheimer's disease model rats].
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognition; Disease Models, Animal; Glucosides; Male; Maze Learning; NF-kappa B; Nitric Oxide; Phenols; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Superoxide Dismutase | 2012 |
Polydatin ameliorates renal injury by attenuating oxidative stress-related inflammatory responses in fructose-induced urate nephropathic mice.
Topics: Animals; Blood Chemical Analysis; Body Weight; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Drugs, Chinese Herbal; Fructose; Glucosides; Inflammation; Interleukin-1beta; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred Strains; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Protective Agents; Stilbenes; Tumor Necrosis Factor-alpha; Uric Acid; Xanthine Oxidase | 2013 |
Emodin-6-O-β-D-glucoside inhibits HMGB1-induced inflammatory responses in vitro and in vivo.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cecum; Cell Adhesion; Cell Movement; Cytoskeleton; Disease Models, Animal; Emodin; Glucosides; HMGB1 Protein; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Ligation; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Monocytes; NF-kappa B; Sepsis; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2013 |
Antispasmodic effect of shakuyakukanzoto extract on experimental muscle cramps in vivo: role of the active constituents of Glycyrrhizae radix.
Topics: Animals; Animals, Outbred Strains; Chalcone; Chalcones; Coumarins; Dantrolene; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drugs, Chinese Herbal; Electric Stimulation; Flavanones; Glucosides; Glycyrrhetinic Acid; Glycyrrhiza; Male; Mice; Muscle Contraction; Muscle Cramp; Muscle, Skeletal; Paeonia; Parasympatholytics; Phytotherapy; Plant Roots; Rats; Rats, Wistar; Rotarod Performance Test; Tibial Nerve | 2013 |
Paeoniflorin protects against ischemia-induced brain damages in rats via inhibiting MAPKs/NF-κB-mediated inflammatory responses.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; bcl-2-Associated X Protein; Benzoates; Brain; Brain Ischemia; Bridged-Ring Compounds; Cerebral Infarction; Cyclooxygenase 2; Cytochromes c; Disease Models, Animal; Gene Expression Regulation; Glucosides; Hippocampus; Inflammation; Interleukin-1beta; Lipoxygenase; Male; Microglia; Mitogen-Activated Protein Kinases; Monoterpenes; Neurons; NF-kappa B; Nitric Oxide Synthase Type II; Proto-Oncogene Proteins c-bcl-2; Rats; Signal Transduction; Tumor Necrosis Factor-alpha | 2012 |
Tetrahydroxystilbene glucoside improves the learning and memory of amyloid-β(₁₋₄₂)-injected rats and may be connected to synaptic changes in the hippocampus.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Glucosides; Hippocampus; Learning Disabilities; Male; Memory Disorders; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Nootropic Agents; Peptide Fragments; Proto-Oncogene Proteins pp60(c-src); Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stilbenes; Synaptic Membranes; Up-Regulation | 2012 |
Paeoniflorin regulates macrophage activation in dimethylnitrosamine-induced liver fibrosis in rats.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Benzoates; Bridged-Ring Compounds; Chemical and Drug Induced Liver Injury; Collagen Type I; Desmin; Dimethylnitrosamine; Disease Models, Animal; Glucosides; Hydroxyproline; Kidney; Liver; Liver Cirrhosis; Lung; Macrophages; Male; Monoterpenes; Paeonia; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Spleen; Tumor Necrosis Factor-alpha | 2012 |
Polydatin--a new mitochondria protector for acute severe hemorrhagic shock treatment.
Topics: Acute Disease; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glucosides; Lipid Peroxidation; Lipid Peroxides; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neurons; Parietal Lobe; Protective Agents; Rats; Rats, Wistar; Severity of Illness Index; Shock, Hemorrhagic; Stilbenes; Survival Analysis | 2013 |
Effects of total glucosides of paeony for delaying onset of Sjogren's syndrome: an animal study.
Topics: Animals; Autoantigens; Disease Models, Animal; Enzyme Inhibitors; Female; Gene Expression Profiling; Glucosides; Hydroxychloroquine; Lymphocytes; Mice; Mice, Inbred NOD; Microarray Analysis; Paeonia; Phytotherapy; Ribonucleoproteins; Saliva; Secretory Rate; Sjogren's Syndrome; SS-B Antigen; Submandibular Gland; T-Lymphocytes, Regulatory | 2013 |
Synergistic interaction between total glucosides and total flavonoids on chronic constriction injury induced neuropathic pain in rats.
Topics: Administration, Oral; Analgesics; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Drugs, Chinese Herbal; Flavonoids; Ganglia, Spinal; Glucosides; Glycyrrhiza; Hyperalgesia; Immunohistochemistry; Ligation; Male; Neuralgia; Paeonia; Pain Perception; Pain Threshold; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sirtuin 1; Time Factors | 2013 |
Effects of salidroside pretreatment on expression of tumor necrosis factor-alpha and permeability of blood brain barrier in rat model of focal cerebralischemia-reperfusion injury.
Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Cerebral Cortex; Disease Models, Animal; Evans Blue; Gene Expression; Glucosides; Male; Phenols; Protective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factor-alpha | 2013 |
Exposure to flaxseed or its purified lignan during suckling inhibits chemically induced rat mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Suckling; Body Weight; Butylene Glycols; Carcinogens; Diet; Disease Models, Animal; Female; Flax; Glucosides; Lactation; Lignans; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Reproduction | 2003 |
Antithrombic and anti-atherogenic effects of partially defatted flaxseed meal using a laser-induced thrombosis test in apolipoprotein E and low-density lipoprotein receptor deficient mice.
Topics: Animals; Arteriosclerosis; Butylene Glycols; Diet; Disease Models, Animal; Flax; Glucosides; Lasers; Male; Mice; Mice, Inbred C57BL; Phytotherapy; Thrombosis | 2003 |
Neuroprotection of catalpol in transient global ischemia in gerbils.
Topics: Animals; Apoptosis; Behavior, Animal; Brain Ischemia; Disease Models, Animal; Female; Gerbillinae; Glucosides; Glutathione Peroxidase; Hippocampus; In Situ Nick-End Labeling; Iridoid Glucosides; Iridoids; Lipid Peroxides; Male; Maze Learning; Neurons; Neuroprotective Agents; Nitric Oxide Synthase | 2004 |
Catalposide, a compound isolated from catalpa ovata, attenuates induction of intestinal epithelial proinflammatory gene expression and reduces the severity of trinitrobenzene sulfonic Acid-induced colitis in mice.
Topics: Animals; Colitis; Cytokines; Disease Models, Animal; Down-Regulation; Gene Expression Regulation; Glucosides; Inflammation; Intestinal Mucosa; Male; Mice; Mice, Inbred BALB C; Severity of Illness Index; Signal Transduction; Trinitrobenzenes | 2004 |
Long-term treatment with the Na+-glucose cotransporter inhibitor T-1095 causes sustained improvement in hyperglycemia and prevents diabetic neuropathy in Goto-Kakizaki Rats.
Topics: Administration, Oral; Animals; Carbonates; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diet; Disease Models, Animal; Enzyme Inhibitors; Female; Glucose; Glucose Tolerance Test; Glucosides; Hyperglycemia; Insulin Resistance; Male; Membrane Glycoproteins; Monosaccharide Transport Proteins; Rats; Rats, Inbred Strains; Rats, Wistar; Sodium; Sodium-Glucose Transporter 1; Time Factors | 2005 |
Anti-lipid peroxidation and protection of liver mitochondria against injuries by picroside II.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cinnamates; Disease Models, Animal; Female; Glucosides; Iridoid Glucosides; Lipid Peroxidation; Male; Mice; Mice, Inbred Strains; Mitochondria, Liver; Mitochondrial Swelling | 2005 |
Neuroprotective effect of paeoniflorin on cerebral ischemic rat by activating adenosine A1 receptor in a manner different from its classical agonists.
Topics: Adenosine-5'-(N-ethylcarboxamide); Animals; Benzoates; Binding, Competitive; Bridged-Ring Compounds; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Glucosides; Infarction, Middle Cerebral Artery; Inhibitory Concentration 50; Ischemic Attack, Transient; Male; Monoterpenes; Neuroprotective Agents; Paeonia; Plant Roots; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Time Factors; Xanthines | 2005 |
Effects of paeoniflorin on the cerebral infarction, behavioral and cognitive impairments at the chronic stage of transient middle cerebral artery occlusion in rats.
Topics: Animals; Arterial Occlusive Diseases; Behavior, Animal; Benzoates; Bridged-Ring Compounds; Cognition; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Glucosides; Infarction, Middle Cerebral Artery; Male; Maze Learning; Monoterpenes; Neuroprotective Agents; Paeonia; Plant Extracts; Rats; Rats, Sprague-Dawley; Recovery of Function; Swimming | 2005 |
Amarogentin can reduce hyperproliferation by downregulation of Cox-II and upregulation of apoptosis in mouse skin carcinogenesis model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Caspase 3; Cell Proliferation; Cyclooxygenase 2; Disease Models, Animal; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Glucosides; In Situ Nick-End Labeling; Iridoids; Male; Medicine, Traditional; Membrane Proteins; Mice; Phytotherapy; Plant Extracts; Skin Neoplasms; Swertia; Up-Regulation | 2006 |
Suppressive effect of verproside isolated from Pseudolysimachion longifolium on airway inflammation in a mouse model of allergic asthma.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Cyclopropanes; Disease Models, Animal; Female; Glucosides; Immunoglobulin E; Interleukin-13; Interleukin-4; Iridoid Glucosides; Iridoids; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Molecular Structure; Mucus; Ovalbumin; Plant Extracts; Pneumonia; Pulmonary Eosinophilia; Quinolines; Sulfides; Veronica | 2006 |
Paeoniflorin attenuates chronic cerebral hypoperfusion-induced learning dysfunction and brain damage in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Biomarkers; Brain Damage, Chronic; Brain Ischemia; Bridged-Ring Compounds; Cerebral Infarction; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalitis; Gliosis; Glucosides; Hippocampus; Infarction, Middle Cerebral Artery; Learning Disabilities; Male; Maze Learning; Memory Disorders; Monoterpenes; Nerve Degeneration; Neuroglia; Neurons; Neuroprotective Agents; NF-kappa B; Rats; Treatment Outcome | 2006 |
Effects of four Si-Wu-Tang's constituents and their combination on irradiated mice.
Topics: Animals; Benzoates; Body Weight; Bone Marrow Cells; Bridged-Ring Compounds; Colony-Forming Units Assay; Coumaric Acids; Disease Models, Animal; Dose-Response Relationship, Radiation; Drugs, Chinese Herbal; Female; Fructose; Gamma Rays; Glucosides; Hematopoietic Stem Cells; Mice; Mice, Inbred C57BL; Monoterpenes; Pyrazines; Radiation-Protective Agents; Stem Cells; Thymus Gland | 2006 |
Involvement of cell adhesion molecules in polydatin protection of brain tissues from ischemia-reperfusion injury.
Topics: Analysis of Variance; Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression; Glucosides; Immunohistochemistry; Intercellular Adhesion Molecule-1; Male; Neural Cell Adhesion Molecules; Neurologic Examination; Neuroprotective Agents; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stilbenes; Vascular Cell Adhesion Molecule-1 | 2006 |
Learning-memory deficit with aging in APP transgenic mice of Alzheimer's disease and intervention by using tetrahydroxystilbene glucoside.
Topics: Age Factors; Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Disease Models, Animal; Glucosides; Learning Disabilities; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pattern Recognition, Visual; Stilbenes | 2006 |
Catalpol modulates the expressions of Bcl-2 and Bax and attenuates apoptosis in gerbils after ischemic injury.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Brain Infarction; Brain Ischemia; Disease Models, Animal; Drug Administration Schedule; Drugs, Chinese Herbal; Female; Gene Expression Regulation, Enzymologic; Gerbillinae; Glucosides; Hippocampus; Immunohistochemistry; In Situ Nick-End Labeling; Iridoid Glucosides; Iridoids; Male; Nerve Degeneration; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Reperfusion Injury; Treatment Outcome | 2006 |
Antispasmodic effects of Rooibos tea (Aspalathus linearis) is mediated predominantly through K+ -channel activation.
Topics: Animals; Apigenin; Aspalathus; Beverages; Diarrhea; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Female; Flavones; Flavonoids; Glucosides; Glyburide; Jejunum; Male; Mice; Mice, Inbred BALB C; Muscle Contraction; Parasympatholytics; Plant Extracts; Potassium Channel Blockers; Potassium Channels; Rabbits; Toxicity Tests, Acute | 2006 |
Protective activity of andrographolide and arabinogalactan proteins from Andrographis paniculata Nees. against ethanol-induced toxicity in mice.
Topics: Acid Phosphatase; Alkaline Phosphatase; Andrographis; Animals; Aspartate Aminotransferases; Central Nervous System Depressants; Chromatography, High Pressure Liquid; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Ethanol; Galactans; Glucosides; India; Kidney Diseases; Lipid Peroxidation; Liver Diseases, Alcoholic; Male; Mice; Phloroglucinol; Protective Agents; Silymarin; Spectroscopy, Fourier Transform Infrared | 2007 |
Protective effects of carotenoids from saffron on neuronal injury in vitro and in vivo.
Topics: Animals; Antioxidants; Brain Infarction; Carotenoids; Caspase 3; Cell Hypoxia; Cell Survival; Crocus; Cyclohexenes; Disease Models, Animal; Glucosides; Glutamate-Cysteine Ligase; Glutathione; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Male; Membrane Lipids; Mice; Molecular Structure; Neurons; Neuroprotective Agents; PC12 Cells; Rats; Structure-Activity Relationship; Terpenes; Time Factors; Vitamin A | 2007 |
Alleviation of osteoarthritis by calycosin-7-O-beta-D-glucopyranoside (CG) isolated from Astragali radix (AR) in rabbit osteoarthritis (OA) model.
Topics: Animals; Anterior Cruciate Ligament; Anti-Inflammatory Agents, Non-Steroidal; Astragalus Plant; Cartilage, Articular; Disease Models, Animal; Glucosides; Glycosaminoglycans; Isoflavones; Menisci, Tibial; Osteoarthritis; Piroxicam; Prostaglandins; Proteins; Rabbits; Random Allocation; Synovial Fluid | 2007 |
Transgenic alfalfa that accumulates piceid (trans-resveratrol-3-O-beta-D-glucopyranoside) requires the presence of beta-glucosidase to inhibit the formation of aberrant crypt foci in the colon of CF-1 mice.
Topics: Acyltransferases; Animals; beta-Glucosidase; Colonic Neoplasms; Disease Models, Animal; Female; Glucosides; Humans; Medicago sativa; Mice; Mice, Inbred Strains; Plants, Genetically Modified; Precancerous Conditions; Random Allocation; Resveratrol; Stilbenes | 2007 |
Effects and mechanisms of Paeoniflorin, a bioactive glucoside from paeony root, on adjuvant arthritis in rats.
Topics: Animals; Arthritis, Experimental; Benzoates; Bridged-Ring Compounds; Cell Proliferation; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Freund's Adjuvant; Gene Expression Regulation; Glucosides; Granulocyte-Macrophage Colony-Stimulating Factor; GTP-Binding Proteins; Interleukin-6; Male; Monoterpenes; Paeonia; Plant Extracts; Rats; Rats, Sprague-Dawley; Synovial Membrane; Vascular Endothelial Growth Factor A | 2007 |
Effects of plant alkylphenols on cytokine production, tyrosine nitration and inflammatory damage in the efferent phase of contact hypersensitivity.
Topics: Animals; Anti-Inflammatory Agents; Asteraceae; Blotting, Western; Chlorogenic Acid; Dermatitis, Contact; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation; Glucosides; Hydroquinones; Interleukin-1beta; Interleukin-4; Mice; Neutrophils; Nitric Oxide Synthase Type II; Random Allocation; Skin; Tumor Necrosis Factor-alpha; Tyrosine | 2007 |
[Protective effects of orientin on myocardial ischemia and hypoxia in animal models].
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Female; Flavonoids; Glucosides; Guinea Pigs; Hypoxia; Male; Mice; Myocardial Ischemia; Platelet Aggregation; Rabbits; Rats; Survival Rate | 2007 |
Antinociceptive effects of systemic paeoniflorin on bee venom-induced various 'phenotypes' of nociception and hypersensitivity.
Topics: Analgesics; Animals; Bee Venoms; Benzoates; Bridged-Ring Compounds; Disease Models, Animal; Glucosides; Hyperalgesia; Male; Monoterpenes; Motor Activity; Naloxone; Pain Threshold; Rats; Rats, Sprague-Dawley | 2007 |
Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-d-glucoside, an active component of Polygonum multiflorum Thunb, on experimental colitis in mice.
Topics: Acetic Acid; Acute Disease; Animals; Anti-Inflammatory Agents; Antioxidants; Chronic Disease; Colitis; Colon; Disease Models, Animal; Dose-Response Relationship, Drug; Gastrointestinal Agents; Glucosides; Malondialdehyde; Mesalamine; Mice; Mitomycin; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Peroxidase; Polygonum; Stilbenes; Superoxide Dismutase; Time Factors | 2008 |
Comparative study of Rhodiola preparations on behavioral despair of rats.
Topics: Administration, Oral; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Depression; Disaccharides; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Glucosides; Male; Molecular Structure; Phenols; Phenylethyl Alcohol; Piper nigrum; Plant Preparations; Plant Roots; Rats; Rats, Wistar; Rhodiola; Stress, Physiological | 2008 |
Anesthetics and natural heme oxygenase-1 inducers: waiting for carbon monoxide?
Topics: Anesthetics; Animals; Anthocyanins; Antioxidants; Carbon Monoxide; Curcumin; Cytoprotection; Disease Models, Animal; Flavonoids; Glucosides; Heme Oxygenase-1; Hepatocytes; Humans; Isoflurane; Liver; Liver Diseases; Liver Transplantation; Phenols; Polyphenols; Propofol; Reperfusion Injury | 2008 |
Antiallergic effect of the root of Paeonia lactiflora and its constituents paeoniflorin and paeonol.
Topics: Acetic Acid; Acetophenones; Analgesics; Animals; Anti-Allergic Agents; Antipruritics; Asthma; Behavior, Animal; Benzoates; Bridged-Ring Compounds; Cell Degranulation; Disease Models, Animal; Dose-Response Relationship, Drug; Glucosides; Male; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Monoterpenes; Ovalbumin; p-Methoxy-N-methylphenethylamine; Paeonia; Pain; Pain Measurement; Passive Cutaneous Anaphylaxis; Plant Roots; Pruritus; Rats; Rats, Sprague-Dawley | 2008 |
Acetoside, a component of Stachys sieboldii MIQ, may be a promising antinephritic agent: effect of acteoside on crescentic-type anti-GBM nephritis in rats.
Topics: Analysis of Variance; Animals; Antibody Formation; Cholesterol; Complement C3; Complement Hemolytic Activity Assay; Creatinine; Disease Models, Animal; Drug Evaluation, Preclinical; gamma-Globulins; Glomerulonephritis; Glucosides; Immunohistochemistry; Immunosuppressive Agents; Kidney Glomerulus; Male; Phenols; Plant Extracts; Proliferating Cell Nuclear Antigen; Proteinuria; Rats; Rats, Sprague-Dawley | 1994 |
[New BRM from kampo-herbal medicine].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigen-Antibody Complex; Autoimmune Diseases; Benzoates; Bridged-Ring Compounds; Disease Models, Animal; Drugs, Chinese Herbal; Female; Glucosides; Macrophage-1 Antigen; Mice; Mice, Inbred MRL lpr; Monoterpenes; Receptors, IgG | 1997 |
New antidiabetic compounds, mangiferin and its glucoside.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucosides; Hyperinsulinism; Hypoglycemic Agents; Male; Mice; Xanthenes; Xanthones | 1998 |
Anticonvulsant activity of paeonimetabolin-I adducts obtained by incubation of paeoniflorin and thiol compounds with Lactobacillus brevis.
Topics: Analysis of Variance; Animals; Anticonvulsants; Benzoates; Bridged-Ring Compounds; Disease Models, Animal; Glucosides; Lactobacillus; Male; Mice; Monoterpenes; Pentylenetetrazole; Seizures; Sulfhydryl Compounds | 1999 |
Dose effects of flaxseed and its lignan on N-methyl-N-nitrosourea-induced mammary tumorigenesis in rats.
Topics: Adenocarcinoma; Animals; Butylene Glycols; Carcinogens; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Flax; Glucosides; Lignans; Mammary Neoplasms, Experimental; Methylnitrosourea; Phytotherapy; Random Allocation; Rats; Rats, Sprague-Dawley | 1999 |
Antidiabetic activity of a xanthone compound, mangiferin.
Topics: Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucosides; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Magnoliopsida; Male; Mice; Phytotherapy; Plant Extracts; Xanthenes; Xanthones | 2001 |
Secoisolariciresinol diglucoside from flaxseed delays the development of type 2 diabetes in Zucker rat.
Topics: Animals; Antioxidants; Blood Glucose; Butylene Glycols; Cholesterol; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Flax; Glucosides; Glycated Hemoglobin; Malondialdehyde; Oxidative Stress; Rats; Rats, Zucker; Triglycerides | 2001 |
Antipruritic and antidermatitic effect of extract and compounds of Impatiens balsamina L. in atopic dermatitis model NC mice.
Topics: Animals; Antipruritics; Behavior, Animal; China; Dermatitis, Atopic; Disease Models, Animal; Drugs, Chinese Herbal; Glucosides; Impatiens; Male; Mice; Mice, Inbred Strains; Naphthoquinones; Phytotherapy; Plant Extracts; Plant Structures; Plants, Medicinal; Pruritus; Quercetin | 2001 |
Stevioside induces antihyperglycaemic, insulinotropic and glucagonostatic effects in vivo: studies in the diabetic Goto-Kakizaki (GK) rats.
Topics: Animals; Area Under Curve; Diabetes Mellitus, Type 2; Disease Models, Animal; Diterpenes; Diterpenes, Kaurane; Glucagon; Glucose; Glucose Tolerance Test; Glucosides; Hyperglycemia; Hypoglycemic Agents; Injections, Intravenous; Insulin; Male; Phytotherapy; Plant Extracts; Rats; Rats, Inbred Strains; Rats, Wistar; Terpenes | 2002 |
Recent observations on Gaucher's disease.
Topics: Aging; Animals; Brain; Ceramides; Disease Models, Animal; Estradiol; Gaucher Disease; Glucosides; Glucosylceramidase; Glycoside Hydrolases; Humans; Infant; Kinetics; Liver; Lysosomes; Mice; Sphingolipids; Sphingosine; Spleen | 1976 |