Compounds > glucose, (beta-d)-isomer
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glucose, (beta-d)-isomer and Cardiac Remodeling, Ventricular

glucose, (beta-d)-isomer has been researched along with Cardiac Remodeling, Ventricular in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (2.22)29.6817
2010's20 (44.44)24.3611
2020's24 (53.33)2.80

Authors

AuthorsStudies
Hao, Z; Liu, Y; Tan, R; Xia, Y; Xiao, W; Xu, G; Yuan, M1
Andres, AM; Germano, JF; Gottlieb, RA; Huang, C; Mentzer, RM; Sin, J; Song, Y; Taylor, DJR; Thakur, R1
Chan, SH; Cheng, HC; Chou, WC; Chu, PM; Hsieh, PL; Huang, YT; Tsai, KL1
Chen, F; Chen, K; Hwa, J; Jiang, K; Qian, J; Wang, D; Wang, H; Wu, Y; Xiang, Y; Xu, Y; Yang, B; Yu, Y; Zhou, C1
Chang, R; Cui, B; Fan, Z; Hiram, R; Huang, C; Huang, H; Liu, T; Shi, S; Su, X; Tang, Y; Wu, G; Wu, J; Xiong, F; Yan, M; Zhang, W1
Ma, H; Ma, Y1
Feng, B; Ma, X; Sun, K; Xu, G; Zhang, N; Zhou, Y1
Hirose, M; Ibi, M; Ishida, N; Matsushita, N; Morino, Y; Saito, M; Sawa, Y; Taira, E1
Chen, P; Han, B; Liu, J; Ruan, H; Wu, P; Yimei, D; Zhang, M1
Auger, C; Benrahla, D; Bruckert, C; Farooq, MA; Gaertner, S; Lee, HH; Lessinger, JM; Mayoux, E; Morel, O; Ohlmann, P; Park, SH; Pollet, B; Qureshi, AW; Schini-Kerth, VB; Stephan, D1
Adam, M; Connelly, K; Meagher, P1
Bami, K; Connelly, KA; Gandhi, S; Garg, V; Gilbert, RE; Ho, E; Jüni, P; Leiter, LA; Leong-Poi, H; Mazer, CD; Ong, G; Quan, A; Teoh, H; Thorpe, KE; Verma, S; Yan, AT; Zahrani, M; Zinman, B; Zuo, F1
Choy, AMJ; Donnan, PT; Fathi, A; Gandy, S; George, J; Houston, JG; Khan, F; Lang, CC; Mohan, M; Mordi, IR; Pearson, ER; Singh, JSS; Struthers, AD; Vickneson, K1
Birnbaum, Y; Chen, H; Nylander, S; Tran, D; Yang, HC; Ye, Y1
Amorosi, A; De Rosa, S; Iaconetti, C; Indolfi, C; Mignogna, C; Polimeni, A; Sabatino, J; Sorrentino, S; Spaccarotella, C; Tammè, L; Yasuda, M1
Asensio Lopez, MDC; Bayes-Genis, A; Fernandez Del Palacio, MJ; Hernandez Vicente, A; Hernandez-Martinez, A; Lax, A; Pascual Figal, DA; Saura Guillen, E1
Boogerd, CJ; de Boer, RA; Dokter, MM; Lam, CSP; Markousis-Mavrogenis, G; Meems, LMG; Schouten, EM; Silljé, HHW; Voors, AA; Westenbrink, BD; Withaar, C1
Katsiki, N; Kotsa, K; Kotsis, V1
Ai, S; Blažek, P; Brittenham, GM; Chen, D; Chen, YP; Cortez, LM; Daude, N; Deisenhofer, I; Dwivedi, G; Eskandari-Sedighi, G; Fegan, PG; Friedrich, L; Fu, B; Gotoh, M; Grebmer, C; Green, G; Habibi, A; Hadadi, M; Hattori, R; Hectors, SJ; Hegde, AR; Iwata, H; Jabłońska, J; Jafari, R; Kantenwein, V; Karami, S; Kato, M; Kawanishi, H; Kluska, M; Koehne de González, AK; Kolb, C; Kulkarni, VI; Lan, NSR; Lan, X; Lennerz, C; Li, C; Li, Q; Li, X; Li, Y; Lim, MA; Lin, CH; Lin, XJ; Liu, R; Manne, ASN; Murase, Y; Mutalik, S; O'Connor, M; Pranata, R; Prince, MR; Rankin, JM; Rao, RR; Raut, SY; Reents, T; Sassa, N; Schaarschmidt, C; Seko, S; Shi, W; Shmeit, K; Sim, V; Spincemaille, P; Sun, G; Sun, J; Tsuzuki, T; Varmira, K; von Olshausen, G; Walker, MJ; Wang, Y; Wang, Z; Waterhouse, GIN; Weigand, S; Westaway, D; Xu, XM; Yang, J; Yeap, BB; Yi, X; Zhang, J; Zhang, M; Zhang, Y; Zheng, J; Zhou, M1
Badimon, JJ; Garcia-Ropero, A; Santos-Gallego, CG1
Guo, R; Li, Y; Ni, J; Xu, Y1
Chen, H; Chen, Q; Jiang, T; Liu, Y; Tang, Y; Yi, T; Yip, KM; Zhang, J; Zhao, Z; Zhu, L1
Advani, A; Advani, SL; Batchu, SN; Connelly, KA; Kabir, G; Liu, Y; Siddiqi, FS; Yerra, VG1
Fu, S; Li, Y; Qian, Z; Wu, Y; Yang, D; Zhu, L1
Chai, D; Chen, X; Chu, Y; Du, H; Lin, J; Lin, X; Liu, J; Ma, K; Ruan, Q; Xie, H; Xu, C; Zeng, J; Zhang, H; Zhang, Y1
Chen, SY; Chen, WT; Lee, CC; Lee, TM1
Brown, AJM; Lang, C; McCrimmon, R; Struthers, A1
Abassi, Z; Hollander, K; Landa, N; Leor, J; Naftali-Shani, N; Rath, L; Rosenthal, T; Younis, F1
Chen, H; Dong, Y; He, X; Li, J; Wang, J1
Connelly, KA; Desjardins, JF; Gilbert, RE; Thai, K; Zhang, Y1
Chen, K; Huang, Y; Liu, X; Lv, L; Sui, Y; Zhang, G; Zhang, Y; Zhuang, Y1
Jiang, A; Li, F; Shi, L; Wang, S; Zhu, D1
Chen, L; Cheng, Y; Han, F; Li, C; Li, T; Li, X; Liu, X; Lu, Y; Sun, B; Xu, L; Xue, M; Yu, X; Zhang, J1
Chang, CY; Chen, WY; Chen, YF; Dai, ZK; Jhuang, WJ; Jhuo, SJ; Lee, AS; Lee, HC; Liu, PL; Shiou, YL1
Badimon, JJ; Flores, E; Fuster, V; Garcia-Ropero, A; Hajjar, RJ; Ishikawa, K; Picatoste, B; Requena-Ibanez, JA; San Antonio, R; Santos-Gallego, CG; Sanz, J; Watanabe, S1
Lehrke, M1
de Boer, RA; Hillebrands, JL; Oberdorf-Maass, SU; Pavez Giani, MG; Schouten, EM; Silljé, HHW; van Goor, H; van Veldhuisen, DJ; Westenbrink, BD; Yurista, SR1
Austria, JA; Garg, B; Netticadan, T; Parikh, M; Pierce, GN; Raj, P; Yu, L1
Bian, ZY; Dai, J; Deng, W; Tang, QZ; Yang, HX; Yuan, Y; Zhang, JY; Zhou, H; Zong, J1
Hu, YE; Wang, F; Xu, XL; Zhang, W; Zhao, C; Zhou, ZY; Zhu, QY1
Deng, J; Ding, W; Dong, M; Liu, J; Liu, Y; Xu, T; Yan, D1
Ding, W; Dong, M; Liao, Y; Liu, J; Liu, S; Liu, Y; Wang, R; Yan, D; Zhang, Y; Zheng, N1
Chen, C; Gao, J; Gao, Y; Guo, J; Wang, H; Wu, R1
Chen, CX; Gao, JP; Gu, WL; Lü, J; Wang, Y; Wu, Q1
Takeo, S; Yagi, A1

Reviews

1 review(s) available for glucose, (beta-d)-isomer and Cardiac Remodeling, Ventricular

ArticleYear
[Anti-inflammatory constituents, aloesin and aloemannan in Aloe species and effects of tanshinon VI in Salvia miltiorrhiza on heart].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2003, Volume: 123, Issue:7

    Topics: Aloe; Animals; Anti-Inflammatory Agents; Chromones; Energy Metabolism; Free Radical Scavengers; Glucosides; Humans; Mannans; Myocardial Ischemia; Myocardial Reperfusion Injury; Phenanthrenes; Salvia miltiorrhiza; Ventricular Remodeling

2003

Trials

4 trial(s) available for glucose, (beta-d)-isomer and Cardiac Remodeling, Ventricular

ArticleYear
Dapagliflozin reduces the vulnerability of rats with pulmonary arterial hypertension-induced right heart failure to ventricular arrhythmia by restoring calcium handling.
    Cardiovascular diabetology, 2022, 09-28, Volume: 21, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Benzhydryl Compounds; Calcium; Connexin 43; Disease Models, Animal; Fura-2; Glucose; Glucosides; Heart Failure; Monocrotaline; Pulmonary Arterial Hypertension; Rats; Sodium; Ventricular Dysfunction, Right; Ventricular Remodeling

2022
Effects of Empagliflozin on Left Ventricular Remodeling in Patients with Type 2 Diabetes and Coronary Artery Disease: Echocardiographic Substudy of the EMPA-HEART CardioLink-6 Randomized Clinical Trial.
    Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2020, Volume: 33, Issue:5

    Topics: Benzhydryl Compounds; Coronary Artery Disease; Diabetes Mellitus, Type 2; Echocardiography; Glucosides; Humans; Ventricular Remodeling

2020
Dapagliflozin Versus Placebo on Left Ventricular Remodeling in Patients With Diabetes and Heart Failure: The REFORM Trial.
    Diabetes care, 2020, Volume: 43, Issue:6

    Topics: Aged; Benzhydryl Compounds; Cohort Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glucosides; Heart Failure; Heart Ventricles; Humans; Male; Middle Aged; Placebos; Stroke Volume; Ventricular Dysfunction, Left; Ventricular Remodeling

2020
Does dapagliflozin regress left ventricular hypertrophy in patients with type 2 diabetes? A prospective, double-blind, randomised, placebo-controlled study.
    BMC cardiovascular disorders, 2017, 08-23, Volume: 17, Issue:1

    Topics: Administration, Oral; Benzhydryl Compounds; Blood Pressure Monitoring, Ambulatory; Clinical Protocols; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Disease Progression; Double-Blind Method; Glucosides; Humans; Hypertrophy, Left Ventricular; Hypoglycemic Agents; Magnetic Resonance Imaging; Proof of Concept Study; Prospective Studies; Research Design; Risk Factors; Scotland; Time Factors; Treatment Outcome; Ventricular Function, Left; Ventricular Remodeling

2017

Other Studies

40 other study(ies) available for glucose, (beta-d)-isomer and Cardiac Remodeling, Ventricular

ArticleYear
Zymosan A Improved Doxorubicin-Induced Ventricular Remodeling by Evoking Heightened Cardiac Inflammatory Responses and Healing in Mice.
    Journal of the American Heart Association, 2023, 09-19, Volume: 12, Issue:18

    Topics: Animals; Doxorubicin; Mice; Myocytes, Cardiac; Ventricular Remodeling; Wound Healing; Zymosan

2023
Attenuation of Adverse Postinfarction Left Ventricular Remodeling with Empagliflozin Enhances Mitochondria-Linked Cellular Energetics and Mitochondrial Biogenesis.
    International journal of molecular sciences, 2021, Dec-31, Volume: 23, Issue:1

    Topics: Animals; Benzhydryl Compounds; Electrocardiography; Energy Metabolism; Glucosides; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Heart; Mitophagy; Myocardial Infarction; Organelle Biogenesis; Ubiquitin-Protein Ligases; Ventricular Remodeling

2021
Dapagliflozin Mitigates Doxorubicin-Caused Myocardium Damage by Regulating AKT-Mediated Oxidative Stress, Cardiac Remodeling, and Inflammation.
    International journal of molecular sciences, 2022, Sep-04, Volume: 23, Issue:17

    Topics: Animals; Apoptosis; Benzhydryl Compounds; Cardiotoxicity; Doxorubicin; Fibrosis; Glucosides; Hypertrophy; Inflammation; Myocardium; Myocytes, Cardiac; NF-E2-Related Factor 2; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Ventricular Remodeling

2022
Bone marrow-derived naïve B lymphocytes improve heart function after myocardial infarction: a novel cardioprotective mechanism for empagliflozin.
    Basic research in cardiology, 2022, 09-28, Volume: 117, Issue:1

    Topics: Animals; B-Lymphocytes; Benzhydryl Compounds; Bone Marrow; Glucosides; Heart Failure; Immunoglobulin D; Immunoglobulin M; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Percutaneous Coronary Intervention; Sodium-Glucose Transporter 2 Inhibitors; Ventricular Remodeling

2022
Dapagliflozin Inhibits Ventricular Remodeling in Heart Failure Rats by Activating Autophagy through AMPK/mTOR Pathway.
    Computational and mathematical methods in medicine, 2022, Volume: 2022

    Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Atrial Natriuretic Factor; Autophagy; Autophagy-Related Proteins; Benzhydryl Compounds; Caspase 3; Glucosides; Heart Failure; Hypoxia; Myocytes, Cardiac; Rats; Signal Transduction; TOR Serine-Threonine Kinases; Ventricular Remodeling

2022
Dapagliflozin improves left ventricular remodeling and aorta sympathetic tone in a pig model of heart failure with preserved ejection fraction.
    Cardiovascular diabetology, 2019, 08-20, Volume: 18, Issue:1

    Topics: Animals; Aorta; Benzhydryl Compounds; Biomarkers; Blood Pressure; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cytokines; Disease Models, Animal; Female; Fibrosis; Glucosides; Heart Failure; Hypertension; Inflammation Mediators; Lipids; Nitric Oxide; Norepinephrine; Sodium-Glucose Transporter 2 Inhibitors; Sus scrofa; Sympathetic Nervous System; Ventricular Function, Left; Ventricular Remodeling

2019
Pretreatment with KGA-2727, a selective SGLT1 inhibitor, is protective against myocardial infarction-induced ventricular remodeling and heart failure in mice.
    Journal of pharmacological sciences, 2020, Volume: 142, Issue:1

    Topics: Animals; Fibrosis; Gene Expression Regulation; Glucosides; Heart Failure; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Pyrazoles; RNA, Messenger; Sodium-Glucose Transporter 1; Ventricular Remodeling

2020
Protective effects of Salidroside on cardiac function in mice with myocardial infarction.
    Scientific reports, 2019, 12-02, Volume: 9, Issue:1

    Topics: Animals; Apoptosis; Cardiotonic Agents; Coronary Vessels; Cytokines; Disease Models, Animal; Fibrosis; Glucosides; Heart; Ligation; Male; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Neovascularization, Physiologic; Phenols; Ventricular Remodeling

2019
Empagliflozin improved systolic blood pressure, endothelial dysfunction and heart remodeling in the metabolic syndrome ZSF1 rat.
    Cardiovascular diabetology, 2020, 02-18, Volume: 19, Issue:1

    Topics: Animals; Benzhydryl Compounds; Biomarkers; Blood Glucose; Blood Pressure; Cellular Senescence; Disease Models, Animal; Endothelium, Vascular; Glucosides; Metabolic Syndrome; Obesity; Rats, Zucker; Sodium-Glucose Transporter 2 Inhibitors; Systole; Ventricular Function, Left; Ventricular Remodeling

2020
It's Not All About the Cardiomyocyte: Fibroblasts, Empagliflozin, and Cardiac Remodelling.
    The Canadian journal of cardiology, 2020, Volume: 36, Issue:4

    Topics: Benzhydryl Compounds; Diabetes Mellitus, Type 2; Extracellular Matrix; Fibroblasts; Glucosides; Humans; Myocytes, Cardiac; Myofibroblasts; Ventricular Remodeling

2020
Dapagliflozin and Ticagrelor Have Additive Effects on the Attenuation of the Activation of the NLRP3 Inflammasome and the Progression of Diabetic Cardiomyopathy: an AMPK-mTOR Interplay.
    Cardiovascular drugs and therapy, 2020, Volume: 34, Issue:4

    Topics: AMP-Activated Protein Kinases; Animals; Benzhydryl Compounds; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Disease Models, Animal; Disease Progression; Enzyme Activation; Fibrosis; Glucosides; Inflammasomes; Male; Mechanistic Target of Rapamycin Complex 2; Mice, Inbred C57BL; Myocytes, Cardiac; NLR Family, Pyrin Domain-Containing 3 Protein; Purinergic P2Y Receptor Antagonists; Signal Transduction; Sodium-Glucose Transporter 2 Inhibitors; Stroke Volume; Ticagrelor; TOR Serine-Threonine Kinases; Ventricular Function, Left; Ventricular Remodeling

2020
Empagliflozin prevents doxorubicin-induced myocardial dysfunction.
    Cardiovascular diabetology, 2020, 05-15, Volume: 19, Issue:1

    Topics: Animals; Benzhydryl Compounds; Cardiomyopathies; Cardiotoxicity; Diastole; Disease Models, Animal; Doxorubicin; Extracellular Signal-Regulated MAP Kinases; Fibrosis; Glucosides; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Sodium-Glucose Transporter 2 Inhibitors; Systole; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling

2020
Empagliflozin improves post-infarction cardiac remodeling through GTP enzyme cyclohydrolase 1 and irrespective of diabetes status.
    Scientific reports, 2020, 08-11, Volume: 10, Issue:1

    Topics: Animals; Benzhydryl Compounds; Diabetes Mellitus, Experimental; Glucosides; GTP Cyclohydrolase; Male; Myocardial Infarction; Rats; Rats, Wistar; Sodium-Glucose Transporter 2 Inhibitors; Ventricular Dysfunction, Left; Ventricular Remodeling

2020
The effects of liraglutide and dapagliflozin on cardiac function and structure in a multi-hit mouse model of heart failure with preserved ejection fraction.
    Cardiovascular research, 2021, 07-27, Volume: 117, Issue:9

    Topics: Angiotensin II; Animals; Benzhydryl Compounds; Blood Glucose; Diet, High-Fat; Disease Models, Animal; Female; Fibrosis; Gene Expression Regulation; Glucagon-Like Peptide-1 Receptor; Glucosides; Heart Failure, Diastolic; Hypertrophy, Left Ventricular; Incretins; Liraglutide; Mice, Inbred C57BL; Myocardium; Signal Transduction; Sodium-Glucose Transporter 2 Inhibitors; Ventricular Function, Left; Ventricular Remodeling

2021
Empagliflozin effects on cardiac remodeling: re-shaping the future of heart failure prevention.
    Expert review of cardiovascular therapy, 2020, Volume: 18, Issue:11

    Topics: Benzhydryl Compounds; Glucosides; Heart Failure; Humans; Ventricular Remodeling

2020
    Journal of clinical orthopaedics and trauma, 2021, Volume: 12, Issue:1

    Topics: Acute Coronary Syndrome; Adolescent; Adsorption; Adult; Aged; Animals; Aspergillus; Aspergillus oryzae; Benzhydryl Compounds; Biocatalysis; Biological Availability; Biomarkers; Biomass; Brain; Brain Injuries, Traumatic; Cadmium; Calorimetry, Differential Scanning; Carbon; Carcinoma, Transitional Cell; Catalysis; Cell Death; Cells, Immobilized; Child; Child, Preschool; China; Chitosan; Creatine Kinase, MB Form; Cyclodextrins; Defibrillators, Implantable; Dendritic Spines; Diabetes Mellitus, Type 2; Diastole; Directed Molecular Evolution; Disease Models, Animal; Disease Progression; Down-Regulation; Electric Countershock; Electrolytes; Electrophoresis, Polyacrylamide Gel; Endopeptidase K; Environmental Monitoring; Esterification; Esters; Feasibility Studies; Female; Fruit; Gene Library; Glial Fibrillary Acidic Protein; Glucosides; Hippocampus; Humans; Hydrogen-Ion Concentration; Hydrolysis; Infant; Infant, Newborn; Inflammation; Ions; Kinetics; Lipase; Liver Cirrhosis; Logistic Models; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malus; Maze Learning; Melatonin; Mercury; Mice; Mice, Inbred C57BL; Middle Aged; Mining; Molecular Docking Simulation; Molecular Weight; Molybdenum; Motor Cortex; Mutagenesis, Site-Directed; Mutation; Neoplasm Recurrence, Local; Nephrectomy; Nephroureterectomy; Neurons; Oxidative Stress; Patient Discharge; Proof of Concept Study; Propionates; Prospective Studies; Protein Engineering; Protein Structure, Quaternary; Protons; PrPC Proteins; PrPSc Proteins; Rats; Rats, Wistar; Recovery of Function; Registries; Retrospective Studies; Rivers; ROC Curve; Scrapie; Sodium-Glucose Transporter 2 Inhibitors; Solubility; Solvents; Spatial Memory; Stereoisomerism; Synapses; Temperature; Time Factors; Treatment Outcome; Troponin T; Urinary Bladder Neoplasms; Urinary Tract; Ventricular Function, Left; Ventricular Remodeling; Water; Water Pollutants, Chemical; Water Purification; X-Ray Diffraction; Young Adult; Zebrafish

2021
Reply: empagliflozin effects on cardiac remodeling: re-shaping the future of heart failure prevention.
    Expert review of cardiovascular therapy, 2021, Volume: 19, Issue:1

    Topics: Benzhydryl Compounds; Glucosides; Heart Failure; Humans; Ventricular Remodeling

2021
Salidroside protects against cardiomyocyte apoptosis and ventricular remodeling by AKT/HO-1 signaling pathways in a diabetic cardiomyopathy mouse model.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2021, Volume: 82

    Topics: Animals; Apoptosis; Diabetic Cardiomyopathies; Disease Models, Animal; Dose-Response Relationship, Drug; Glucosides; Heme Oxygenase-1; Male; Mice; Myocytes, Cardiac; Phenols; Proto-Oncogene Proteins c-akt; Signal Transduction; Ventricular Remodeling

2021
A hybrid platform featuring nanomagnetic ligand fishing for discovering COX-2 selective inhibitors from aerial part of Saussurea laniceps Hand.-Mazz.
    Journal of ethnopharmacology, 2021, May-10, Volume: 271

    Topics: Animals; Arthritis, Experimental; Celecoxib; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Discovery; Drugs, Chinese Herbal; Glucosides; Joints; Ligands; Magnetic Iron Oxide Nanoparticles; Molecular Docking Simulation; Muscle Cells; Nanoconjugates; Osteoarthritis; Phenylpropionates; Plant Components, Aerial; Rats, Sprague-Dawley; Saussurea; Scopoletin; Ventricular Remodeling

2021
Empagliflozin Disrupts a Tnfrsf12a-Mediated Feed Forward Loop That Promotes Left Ventricular Hypertrophy.
    Cardiovascular drugs and therapy, 2022, Volume: 36, Issue:4

    Topics: Animals; Benzhydryl Compounds; Glucosides; Heart Failure; Hypertrophy, Left Ventricular; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Sodium-Glucose Transporter 2; TWEAK Receptor; Ventricular Remodeling

2022
Icarrin prevents cardiomyocyte apoptosis in spontaneously hypertensive rats by inhibiting endoplasmic reticulum stress pathways.
    The Journal of pharmacy and pharmacology, 2021, Jul-07, Volume: 73, Issue:8

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Flavonoids; Glucosides; Heart Ventricles; Hypertension; Myocytes, Cardiac; Protective Agents; Rats; Rats, Inbred SHR; Signal Transduction; Treatment Outcome; Ventricular Dysfunction, Left; Ventricular Remodeling

2021
Dapagliflozin: a sodium-glucose cotransporter 2 inhibitor, attenuates angiotensin II-induced cardiac fibrotic remodeling by regulating TGFβ1/Smad signaling.
    Cardiovascular diabetology, 2021, 06-11, Volume: 20, Issue:1

    Topics: Angiotensin II; Animals; Antifibrotic Agents; Benzhydryl Compounds; Cells, Cultured; Disease Models, Animal; Fibroblasts; Fibrosis; Glucosides; Hypertrophy, Left Ventricular; Male; Myocardium; Rats, Sprague-Dawley; Signal Transduction; Smad Proteins; Sodium-Glucose Transporter 2 Inhibitors; Transforming Growth Factor beta1; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling

2021
Dapagliflozin attenuates arrhythmic vulnerabilities by regulating connexin43 expression via the AMPK pathway in post-infarcted rat hearts.
    Biochemical pharmacology, 2021, Volume: 192

    Topics: AMP-Activated Protein Kinases; Animals; Arrhythmias, Cardiac; Benzhydryl Compounds; Connexin 43; Gene Expression; Glucosides; Male; Myocardial Infarction; Rats; Rats, Wistar; Sodium-Glucose Transporter 2 Inhibitors; Ventricular Remodeling

2021
Beneficial Effect of the SGLT2 Inhibitor Empagliflozin on Glucose Homeostasis and Cardiovascular Parameters in the Cohen Rosenthal Diabetic Hypertensive (CRDH) Rat.
    Journal of cardiovascular pharmacology and therapeutics, 2018, Volume: 23, Issue:4

    Topics: Animals; Benzhydryl Compounds; Biomarkers; Blood Glucose; Blood Pressure; Diabetes Mellitus; Disease Models, Animal; Glucosides; Homeostasis; Hypertension; Hypertrophy, Left Ventricular; Insulin Resistance; Kidney; Male; Pancreas; Proteinuria; Rats, Inbred SHR; Sodium-Glucose Transporter 2 Inhibitors; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling

2018
Paeoniflorin improves cardiac function and decreases adverse postinfarction left ventricular remodeling in a rat model of acute myocardial infarction.
    Drug design, development and therapy, 2018, Volume: 12

    Topics: Acute Disease; Animals; Apoptosis; Disease Models, Animal; Glucosides; Heart Function Tests; Male; Monoterpenes; Myocardial Infarction; Myocardium; Rats; Rats, Wistar; Ventricular Function, Left; Ventricular Remodeling

2018
Dual inhibition of sodium-glucose linked cotransporters 1 and 2 exacerbates cardiac dysfunction following experimental myocardial infarction.
    Cardiovascular diabetology, 2018, 07-07, Volume: 17, Issue:1

    Topics: Animals; Benzhydryl Compounds; Carbonates; Disease Models, Animal; Glucosides; Hypertrophy, Left Ventricular; Male; Myocardial Infarction; Myocardium; Rats, Inbred F344; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling

2018
Paeoniflorin improves pressure overload-induced cardiac remodeling by modulating the MAPK signaling pathway in spontaneously hypertensive rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 111

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Gene Regulatory Networks; Glucosides; Hypertension; Male; MAP Kinase Signaling System; Monoterpenes; Paeonia; Rats; Rats, Inbred SHR; Ventricular Remodeling

2019
Dapagliflozin Attenuates Cardiac Remodeling in Mice Model of Cardiac Pressure Overload.
    American journal of hypertension, 2019, 04-22, Volume: 32, Issue:5

    Topics: Animals; Benzhydryl Compounds; Blotting, Western; Cardiomyopathies; Disease Models, Animal; Echocardiography; Fibrosis; Glucosides; Heart Ventricles; Hypertrophy, Left Ventricular; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Sodium-Glucose Transport Proteins; Sodium-Glucose Transporter 2 Inhibitors; Ventricular Function, Left; Ventricular Pressure; Ventricular Remodeling

2019
SGLT2 inhibition with empagliflozin attenuates myocardial oxidative stress and fibrosis in diabetic mice heart.
    Cardiovascular diabetology, 2019, 02-02, Volume: 18, Issue:1

    Topics: Animals; Antioxidant Response Elements; Antioxidants; Benzhydryl Compounds; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Disease Models, Animal; Fibrosis; Glucosides; Mice, Inbred C57BL; Myocardium; NF-E2-Related Factor 2; Oxidative Stress; Phosphorylation; Signal Transduction; Smad Proteins; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Transforming Growth Factor beta1; Ventricular Function, Left; Ventricular Remodeling

2019
The sodium-glucose co-transporter 2 inhibitor empagliflozin attenuates cardiac fibrosis and improves ventricular hemodynamics in hypertensive heart failure rats.
    Cardiovascular diabetology, 2019, 04-01, Volume: 18, Issue:1

    Topics: Animals; Atrial Function, Left; Atrial Natriuretic Factor; Benzhydryl Compounds; Diet, High-Fat; Disease Models, Animal; Fatty Acids; Fibrosis; Gene Expression Regulation; Glucosides; Heart Failure; Hemodynamics; Hypertension; Male; Myocardium; Natriuretic Peptide, Brain; Rats, Inbred SHR; Rats, Inbred WKY; Recovery of Function; Sodium-Glucose Transporter 2 Inhibitors; Tumor Necrosis Factor-alpha; Ventricular Function, Left; Ventricular Remodeling

2019
Empagliflozin Ameliorates Adverse Left Ventricular Remodeling in Nondiabetic Heart Failure by Enhancing Myocardial Energetics.
    Journal of the American College of Cardiology, 2019, 04-23, Volume: 73, Issue:15

    Topics: Analysis of Variance; Animals; Benzhydryl Compounds; Diabetes Mellitus; Disease Models, Animal; Echocardiography, Three-Dimensional; Glucosides; Heart Failure; Heart Function Tests; Random Allocation; Reference Values; Sodium-Glucose Transporter 2 Inhibitors; Statistics, Nonparametric; Stroke Volume; Swine; Treatment Outcome; Ventricular Function, Left; Ventricular Remodeling

2019
SGLT2 Inhibition: Changing What Fuels the Heart.
    Journal of the American College of Cardiology, 2019, 04-23, Volume: 73, Issue:15

    Topics: Benzhydryl Compounds; Glucosides; Heart Failure; Humans; Sodium-Glucose Transporter 2; Ventricular Remodeling

2019
Sodium-glucose co-transporter 2 inhibition with empagliflozin improves cardiac function in non-diabetic rats with left ventricular dysfunction after myocardial infarction.
    European journal of heart failure, 2019, Volume: 21, Issue:7

    Topics: Animals; Benzhydryl Compounds; Echocardiography; Energy Metabolism; Glucosides; Heart Failure; Myocardial Infarction; Rats; Sodium-Glucose Transporter 2 Inhibitors; Treatment Outcome; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling

2019
Dietary flaxseed protects against ventricular arrhythmias and left ventricular dilation after a myocardial infarction.
    The Journal of nutritional biochemistry, 2019, Volume: 71

    Topics: alpha-Linolenic Acid; Animals; Arrhythmias, Cardiac; Body Weight; Butylene Glycols; Cardiotonic Agents; Dietary Supplements; Electrocardiography; Fatty Acids; Flax; Glucosides; Male; Myocardial Infarction; Myocarditis; Organ Size; Rats, Sprague-Dawley; Ventricular Remodeling

2019
Paeoniflorin attenuates pressure overload-induced cardiac remodeling via inhibition of TGFβ/Smads and NF-κB pathways.
    Journal of molecular histology, 2013, Volume: 44, Issue:3

    Topics: Animals; Apoptosis; Benzoates; Biomarkers; Bridged-Ring Compounds; Cardiomegaly; Fibrosis; Glucosides; Heart; Inflammation; Male; Mice; Mice, Inbred C57BL; Monoterpenes; Myocytes, Cardiac; NF-kappa B; Signal Transduction; Smad Proteins; Transforming Growth Factor beta; Ventricular Function, Left; Ventricular Remodeling

2013
The effect of 2,3,4',5-tetrahydroxystilbene-2-O-β-D-glucoside on pressure overload-induced cardiac remodeling in rats and its possible mechanism.
    Planta medica, 2014, Volume: 80, Issue:2-3

    Topics: Animals; Blood Pressure; Glucosides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phytotherapy; Plant Extracts; Polygonum; Rats; Stilbenes; Transforming Growth Factor beta1; Ventricular Remodeling

2014
Polydatin attenuates cardiac hypertrophy through modulation of cardiac Ca2+ handling and calcineurin-NFAT signaling pathway.
    American journal of physiology. Heart and circulatory physiology, 2014, Sep-01, Volume: 307, Issue:5

    Topics: Active Transport, Cell Nucleus; Animals; Atrial Natriuretic Factor; Calcineurin; Calcium; Calcium Signaling; Cardiomegaly; Cell Nucleus; Cells, Cultured; Glucosides; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocytes, Cardiac; Myosin Heavy Chains; NFATC Transcription Factors; Phenylephrine; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum; Stilbenes; Ventricular Remodeling

2014
Polydatin prevents hypertrophy in phenylephrine induced neonatal mouse cardiomyocytes and pressure-overload mouse models.
    European journal of pharmacology, 2015, Jan-05, Volume: 746

    Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cardiomegaly; Cardiotonic Agents; Cell Size; Cells, Cultured; Disease Models, Animal; Drugs, Chinese Herbal; Glucosides; Heart Failure; Heart Ventricles; Male; Mice, Inbred C57BL; Oxidative Stress; Phenylephrine; Rats; rho-Associated Kinases; Stilbenes; Ventricular Remodeling

2015
Cardioprotective effect of polydatin on ventricular remodeling after myocardial infarction in coronary artery ligation rats.
    Planta medica, 2015, Volume: 81, Issue:7

    Topics: Aldosterone; Animals; Antioxidants; Captopril; Collagen; Coronary Occlusion; Coronary Vessels; Endothelin-1; Glucosides; Heart Ventricles; Hydroxyproline; Hypertrophy; Male; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Nitric Oxide; Phytotherapy; Plant Extracts; Polygonum; Rats, Sprague-Dawley; Renin-Angiotensin System; Stilbenes; Ventricular Remodeling

2015
Effects of polydatin on attenuating ventricular remodeling in isoproterenol-induced mouse and pressure-overload rat models.
    Fitoterapia, 2010, Volume: 81, Issue:7

    Topics: Aldosterone; Angiotensin II; Animals; Aorta, Abdominal; Blood Pressure; Cardiovascular Agents; Collagen; Cyclic AMP; Drugs, Chinese Herbal; Endothelin-1; Fallopia japonica; Glucosides; Heart; Hypertrophy, Left Ventricular; Isoproterenol; Male; Mice; Myocytes, Cardiac; Organ Size; Phytotherapy; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Stilbenes; Tumor Necrosis Factor-alpha; Ventricular Remodeling

2010