glucagon-like-peptide-1 and Sleep-Apnea-Syndromes

Rapid gastric emptying has been proposed to justify the increase in glucagon-like polypeptide-1 (GLP-1) after laparoscopic sleeve gastrectomy (LSG).. To assess gastric emptying changes after LSG and their relationship with GLP-1 secretion.. San Salvatore Hospital general surgery unit, University of L'Aquila, Italy.. 52 patients underwent gastric emptying scintigraphy for liquid and solid foods, before and 3 months after LSG. Twenty-six patients were in the liquid group (L group) and the remaining in the solid group (S group). We evaluated the half time of gastric emptying (T. The rapid gastric emptying 3 months after LSG upregulates the production of GLP-1 in the distal bowel. Further studies are needed to confirm these findings.

Topics: Adult; Analysis of Variance; Bariatric Surgery; Female; Gastrectomy; Gastric Emptying; Glucagon-Like Peptide 1; Humans; Hypertension; Hypothyroidism; Laparoscopy; Male; Obesity, Morbid; Sleep Apnea Syndromes; Up-Regulation