Compounds > glucagon
Page last updated: 2024-09-04

glucagon and Insulin Resistance

glucagon has been researched along with Insulin Resistance in 694 studies

Research

Studies (694)

TimeframeStudies, this research(%)All Research%
pre-1990148 (21.33)18.7374
1990's113 (16.28)18.2507
2000's141 (20.32)29.6817
2010's234 (33.72)24.3611
2020's58 (8.36)2.80

Authors

AuthorsStudies
Asadi, F; Dhanvantari, S1
Chen, X; Tripathy, D1
Kamalanathan, S; Roy, A; Sahoo, J1
Bao, J; Li, L; Liu, D; Lv, Y; Ni, M; Qi, L; Sj, P; Su, J; Wang, L; Wang, Q; Wei, Q; Xia, H1
Borer, KT; Lin, PJ; Wuorinen, E1
Kareenhalli, V; Somvanshi, PR; Tomar, M1
Anno, M; Fujioka, Y; Imamura, T; Ito, Y; Izawa, S; Kato, M; Kitao, S; Matsumoto, K; Matsuzawa, K; Nakamura, R; Okura, H; Okura, T; Shoji, K; Taniguchi, SI; Ueta, E; Yamamoto, K1
Bao, J; Cheng, H; Li, L; Liu, D; Lv, Y; Qi, L; Qiu, Y; Su, J; Su, X; Sun, J; Wei, Q; Ye, Z; Yu, X; Zhang, Y1
Aas Holm, L; Ängquist, L; Christiansen, M; de Retana Alzola, IF; Fonvig, CE; Frithioff-Bøjsøe, C; Hansen, T; Hartmann, B; Holm, JC; Holst, JJ; Jonsson, AE; Lund, MAV; Pedersen, O; Stinson, SE; Sørensen, TIA1
Chepurny, OG; Collier, JJ; Cooney, RN; Holz, GG; Leech, CA; Meng, Q; Molnar, ME; Pruekprasert, N1
Jain, G; Kumar, R; Pahadiya, H; Srivastava, S1
Coskun, T; DeVries, JH; Haupt, A; Heise, T; Li, J; Mari, A; Mather, KJ; Milicevic, Z; Pratt, EJ; Thomas, MK; Urva, S1
Guanfu, L; Jun, S; Qiaoli, G; Xiaoyun, W; Xuanjun, W; Yinghao, W1
Barbot, M; Basso, D; Ceccato, F; Giordano, C; Guarnotta, V; Mondin, A; Regazzo, D; Scaroni, C1
Sahoo, B; Sharma, R; Srivastava, A; Tiwari, S1
Anderlova, K; Bendlova, B; Krejci, H; Pacini, G; Sladek, M; Sumova, A; Tura, A; Vankova, M; Vcelak, J; Vejrazkova, D1
da Silva, AA; Damasceno, DC; Dos Santos, VH; Ferreira, DOL; Fioratti, EG; Gonçalves, RC; Hooper, HB; Polizel, DM; Santarosa, BP; Sinzato, YK1
Ahlström, H; Bergsten, P; Forslund, A; Kullberg, J; Manell, H; Mangge, H; Maruszczak, K; Mörwald, K; Pixner, T; Radzikowski, K; Schütz, S; Weghuber, D1
Hüttl, M; Malinska, H; Markova, I; Miklankova, D; Stankova, B1
Eguchi, H; Fujita, Y; Horii, T; Ishibashi, C; Kawata, S; Kozawa, J; Miyagawa, JI; Nammo, T; Ozawa, H; Shimomura, I; Yoneda, S1
Chen, X; Liu, H; Lu, Y; Lu, Z; Meng, F; Zhao, H1
Han, C; Jiang, Y; Ma, W; Qiao, A; Qin, G; Yan, B; Zhou, J1
Li, R; Zhang, R; Zhao, Q1
Chen, X; DeFronzo, RA; Merovci, A; Tripathy, D1
Behn, CGD; Chan, CL; Finn, E; Garrish, J; Nadeau, KJ; Pyle, L; Sagel, SD; Severn, C; Vigers, T; Zeitler, PS1
Chen, L; Chen, W; Cui, W; Hu, X; Li, X; Shang, H; Sun, X; Wang, J; Wu, J; Xiao, RP; Yuan, Y; Zeng, F; Zhang, J; Zhang, X; Zheng, W1
Asadi, J; Jazi, MS; Kiaei, M; Safarzad, M1
Barhod, E; Brandt, B; Hemi, R; Mazaki-Tovi, S; Mdah, R; Rathaus, M; Ron, I; Tirosh, A; Ulman, RY; Zemet, R1
Chu, H; de Souza, CO; Holland, WL; Huang, L; Kohler, JJ; Mineo, C; Oh, DY; Paschoal, VA; Peng, J; Shaul, PW; Varre, JV; Xiao, X; Xu, L; Yu, L1
Kahn, BB; Nelson, AT; Peroni, OD; Saghatelian, A; Santoro, A; Siegel, D; Zhou, P1
Chen, S; Klein, S; Scherer, PE; Smith, GI; Stern, JH; Unger, RH1
Di Mauro, S; Di Pino, A; Filippello, A; Marchisello, S; Piro, S; Purrello, F; Rabuazzo, AM; Scamporrino, A; Scicali, R; Urbano, F1
Craig, SL; Flatt, PR; Gault, VA; Hasib, A; Irwin, N; Khan, D1
Abarkan, M; Gaitan, J; Jaffredo, M; Lang, J; Lebreton, F; Magnan, C; Mulle, C; Perrier, R; Raoux, M1
Chidlow, SJ; Fitches, MJ; Kelly, RA; Pop, SR; Webb, SD1
Bocchio-Chiavetto, L; Bonetto, C; Bruschi, C; D'Agostino, A; Faravelli, C; Furlato, K; Gennarelli, M; Imbesi, M; Lasalvia, A; Minelli, A; Preti, A; Ruggeri, M; Scocco, P; Tomassi, S; Tosato, S; Zanardini, R1
Dybjer, E; Engström, G; Helmer, C; Nägga, K; Nilsson, PM; Rorsman, P1
Feng, Q; Feng, Y; Hu, J; Qu, H; Song, X; Xu, X; Yin, S; Zhang, L1
Abdel-Wahab, YH; Conlon, JM; Flatt, PR; Graham, GV1
Flatt, PR; Irwin, N; Moffett, RC; Tanday, N1
Giau, VV; Nguyen, TKO; Nguyen, TT; Nguyen, TTD; Ta, QTH1
Kitamura, T; Kobayashi, M; Kusunoki, Y; Matsuo, T; Namba, M; Satoh, H; Tokushima, M; Watada, H1
Bandyopadhyay, GK; Brenner, D; Kisseleva, T; Lam, K; Lee, YS; Liu, X; Moon, JS; Riopel, M; You, S1
Crakes, KR; Gilor, C; Greathouse, RL; Huising, MO; Miller, M; Pires, J; Quach, N1
Cai, HL; Chen, T; Cheng, M; Cheng, XB; Huang, HY; Lu, Y; Su, JB; Wang, X; Wang, XH; Wang, XQ; Xu, F; Zhang, DM; Zhang, XL; Zhao, LH1
Brøsen, K; Bøtker, HE; Dollerup, OL; Frøkiær, J; Hansson, NH; Jespersen, NR; Jessen, N; Larsen, AH; Møller, N; Nørrelund, H; Wiggers, H1
Andersen, DB; Bisgaard, HC; Dall, M; Eriksen, PL; Galsgaard, KD; Gillum, MP; Gluud, LL; Hassing, AS; Holst, JJ; Hunt, JE; Jepsen, SL; Kjeldsen, SAS; Knop, FK; Kuhre, RE; Pedersen, J; Santos, A; Sulek, K; Torekov, SS; Trammell, SAJ; Treebak, JT; Vasilopoulou, CG; Vilstrup, H; Werge, MP; Wewer Albrechtsen, NJ; Windeløv, JA; Winther-Sørensen, M; Ørskov, C1
Di Mauro, S; Di Pino, A; Filippello, A; Malaguarnera, R; Piro, S; Purrello, F; Scamporrino, A; Scicali, R1
Ahrén, B; Pacini, G3
Adamski, J; Gar, C; Haschka, SJ; Holst, JJ; Kern-Matschilles, S; Lechner, A; Prehn, C; Rauch, B; Sacco, V; Seissler, J; Wewer Albrechtsen, NJ1
Flatt, PR; Irwin, N; McCloskey, AG; McKillop, AM; Moffett, RC; Mohan, S1
Chen, X; DeFronzo, RA; Maldonado, E; Tripathy, D1
Box, JR; Karikoski, NP; Raekallio, MR; Tanskanen, HE1
Birkenfeld, AL; Dannecker, C; Fritsche, A; Häring, HU; Heni, M; Hummel, J; Peter, A; Stefan, N; Vosseler, A; Wagner, R1
Abiru, N; Akazawa, S; Haraguchi, A; Hasegawa, Y; Horie, I; Ito, A; Kawakami, A; Miura, K; Miura, S; Miwa, M; Nagata, A; Natsuda, S; Shigeno, R1
Ahrén, B; Burattini, L; Göbl, C; Morettini, M; Pacini, G; Tura, A1
Bagger, JI; Becker, U; Bergmann, SS; Dalsgaard, NB; Demant, M; Foghsgaard, S; Gasbjerg, LS; Gether, L; Gillum, MP; Grønbæk, H; Grøndahl, MFG; Holst, JJ; Knop, FK; Knop, J; Kønig, MJ; Lanng, AR; Strandberg, C; Suppli, MP; Thomasen, M; Vilsbøll, T; Wewer Albrechtsen, NJ1
Han, DJ; Jung, CH; Jung, JH; Kim, DH; Kim, YH; Ko, Y; Kwon, H; Lim, SJ; Mun, S; Shin, S1
Ahrén, B1
Engelhardt, JF; Gibson-Corley, KN; He, N; Liang, B; Norris, AW; Sun, X; Uc, A; Yi, Y1
Boriboun, C; Deng, J; Habegger, KM; Kim, T; Ma, W; Ma, YC; Qiao, A; Qin, G; Qiu, H; Richard, S; Song, Y; Xu, S; Yan, B; Yang, L; Zhang, C; Zhang, E; Zhang, J; Zhou, J1
Baixeras, E; Decara, J; Gutiérrez-Adan, A; Ledesma, JC; Medina-Vera, D; Navarro, JA; Pavón, FJ; Rodríguez de Fonseca, F; Rosell-Valle, C; Sanjuan, C; Tovar, R1
Ameneiro, C; Beiroa, D; Bernardo, G; Bilbao, J; Bravo, SB; Carneiro, C; Cho, JW; Coppari, R; Cuñarro, J; Da Silva Lima, N; Dieguez, C; Dp Chantada-Vazquez, M; Fernandez, U; Fernández-Ramos, D; Ferno, J; Fidalgo, M; Fondevila, MF; Fruhbeck, G; Garcia-Vence, M; Gonzalez-Rellan, MJ; Guallar, D; Herzig, S; Iglesias, C; López, M; Lopitz-Otsoa, F; Martinez-Chantar, ML; Mato, JM; Millet, O; Müller, TD; Nogueiras, R; Novoa, E; Perez-Fernandez, R; Porteiro, B; Rodríguez, A; Sabio, G; Senra, A; Seoane, S; Tovar, S; Varela-Rey, M; Veyrat-Durebex, C; Vidal, A; Woodhoo, A; Yang, WH1
Benatti, FB; Bonfá, E; Borba, E; Dantas, WS; Gualano, B; Miyake, CNH; Neves, W; Pereira, RM; Pereira, RT; Roschel, H; Sá-Pinto, AL; Shinjo, SK; Silva, ER; Zambelli, VO1
Guo, J; Li, B; Wang, C; Xi, Z; Xu, J; Zuo, Z1
Li, YC; Li, YJ; Qiao, JY; Shen, JD; Wei, Y1
Deem, JD; Morton, GJ; Muta, K; Scarlett, JM; Schwartz, MW1
Greer, J; Kaur, K; Porter, RR; Wang, X; Youngstedt, SD1
Ahn, CW; Kang, S; Kim, KR; Kim, M; Lee, M; Lee, S; Park, JS; You, J1
Christensen, M; Galsgaard, KD; Holst, JJ; Hædersdal, S; Junker, AE; Knop, FK; Lund, AM; Vilsbøll, T; Wewer Albrechtsen, NJ; Wibrand, F1
Burrin, D; Chacko, S; Chan, L; Guan, X; Li, D; Li, F; Shi, X1
Bódis, K; Bönhof, G; Burkart, V; Markgraf, DF; Müssig, K; Püttgen, S; Roden, M; Strom, A; Szendroedi, J; Ziegler, D1
Bailey, KR; Cobelli, C; Man, CD; Rizza, RA; Shah, M; Sharma, A; Varghese, RT; Vella, A1
Goode, JP; McMahon, C; Poppitt, SD; Silvestre, MP; Tay, A; Vlaskovsky, P1
Jiang, ZH; Li, CG; Li, CJ; Li, Z; Ni, CL; Sun, B; Tang, YZ; Yang, M; Zhu, YJ1
Aithal, GP; Douglas, JA; King, JA; Misu, H; Nimmo, MA; Sargeant, JA; Stensel, DJ; Takamura, T; Takayama, H; Turner, MC; Webb, DR; Yates, T1
Færch, K; Galsgaard, KD; Hansen, T; Holst, JJ; Jensen, TM; Jonsson, AE; Jørgensen, ME; Knop, FK; Lauritzen, T; Mahendran, Y; Pedersen, J; Pedersen, O; Torekov, SS; Vistisen, D; Wewer Albrechtsen, NJ; Winther-Sørensen, M; Witte, DR1
Haluzík, M; Holubová, M; Hrubá, L; Kuneš, J; Maletínská, L; Mikulášková, B; Pražienková, V; Železná, B; Zemenová, J1
Boston, RC; Ehrensing, G; Frank, N; Newkirk, KM; Odoi, A1
Kelly, VP; Naito, A; Nakajima, M; Nakajima, O; Nakano, H; Nohara, H; Okano, S; Saitoh, S; Shirasawa, N; Takahashi, K; Tanaka, T; Yamamoto, M1
Adams-Huet, B; Burgess, S; Li, X; Lingvay, I; Mari, A; Mitchell, L; Pop, LM; Zhao, TJ1
Jun, HS; Lee, YS1
Benatti, FB; Bonfá, E; Borba, E; Dantas, WS; Gualano, B; Miyake, CNH; Pereira, RMR; Sá-Pinto, AL; Shinjo, SK; Silva, MER; Zambelli, VO1
Han, J; Zhao, M1
Li, WH; Nan, M1
Blüher, M; Heindl, M; Hoffmeister, A; Hollenbach, M; Kern, M; Klöting, N; Lorenz, J; Mössner, J; Sommerer, I1
Emfinger, CH; Hruz, PW; Hung, P; McAllister, W; Nichols, CG; Remedi, MS; Welscher, A; Yan, Z1
Araujo, TR; Bonfleur, ML; Boschero, AC; Carneiro, EM; da Silva, JA; Freitas, IN; Lubaczeuski, C; Magalhães, EA; Ribeiro, ES; Ribeiro, RA; Silva, JN; Vettorazzi, JF1
Alcala-Diaz, JF; Arenas-Larriva, AP; Camargo, A; Delgado-Lista, J; Jimenez-Lucena, R; Leon-Acuña, A; Lopez-Miranda, J; Malagon, MM; Ordovas, JM; Perez-Martinez, P; Rangel-Zuñiga, OA; Roncero-Ramos, I; Vals-Delgado, C1
Choi, D; Jung, CH; Kang, SK; Kim, BY; Kim, CH; Lee, B; Moh Moh, MA; Mok, JO1
Di Mauro, S; Di Pino, A; Filippello, A; Piro, S; Purrello, F; Rabuazzo, AM; Scamporrino, A; Scicali, R; Urbano, F1
Besse-Patin, A; Estall, JL; Jeromson, S; Laplante, M; Levesque-Damphousse, P; Secco, B1
Abdul-Ghani, M; Basu, R; DeFronzo, RA; Merovci, A; Tripathy, D1
Chamorro, R; Forck, N; Hallschmid, M; Lehnert, H; Mölle, M; Sayk, F; Schmid, SM; Schultes, B; Trost, D; Wilms, B1
Basu, A; Basu, R; Keenan, DM; Veldhuis, JD1
Galsgaard, KD; Gromada, J; Holst, JJ; Janah, L; Knop, FK; Pedersen, J; Suppli, MP; Vilstrup, H; Wewer Albrechtsen, NJ; Winther-Sørensen, M1
Bhansali, A; Bhansali, S; Bhat, K; Dutta, P; Kochhar, R; Kurpad, AV; Mudaliar, S; Mukherjee, KK; Sachdeva, N; Shekhawat, VS; Sinha, SK; Vaiphei, K1
Chen, Y; Guo, S; Guo, X; He, L; Li, L; Li, X; Pan, Q; Qi, Y; Shen, JZ; Sun, Y; Threadgill, D; Villarreal, D; White, MF; Wu, Y; Xie, W; Xu, Z; Yan, H; Zhang, K; Zhang, W; Zheng, H1
Alcala, M; Calay, ES; Claiborn, KC; Eguchi, K; Garg, R; Heianza, Y; Hollander, KS; Hotamisligil, GS; Inouye, KE; Livne, R; Qi, L; Rathaus, M; Ron, I; Shai, I; Tirosh, A; Tuncman, G1
Fujimoto, K; Ichikawa, R; Kitamura, T; Kobayashi, M; Motomiya, T; Shichiri, M; Takano, K1
Ahlers, M; Laferrère, B; Levesque, K; Mark, V; Patel, K; Pierini, E; Rojas, B; Shah, A1
da Silva, MER; Dagogo-Jack, S; de Sousa, MV; Fukui, R; Krustrup, P; Zouhal, H1
Fujimoto, K; Honzawa, N; Kitamura, T1
Calanna, S; Di Pino, A; Maria Rabuazzo, A; Maria Zagami, R; Piro, S; Purrello, F; Urbano, F1
Bagger, JI; Bonde, L; Holst, JJ; Knop, FK; Larsen, S; Nielsen, T; Svare, JA; Vilsbøll, T1
Abdul-Ghani, MA1
Akiyama, M; Hambro, B; Hu, J; Kennedy, RT; Kulkarni, RN; Liew, CW; Lu, S; Martinez, R1
Bano, G1
Arany, E; Bettler, B; Bonaventura, MM; Chamson-Reig, A; Crivello, M; Libertun, C; Lux-Lantos, V1
Ağbaht, K; Baskal, N; Emral, R; Erdogan, MF; Güllü, S1
Casamitjana, R; Delgado, S; Flores, L; Jiménez, A; Lacy, A; Vidal, J1
Bojsen-Møller, KN; Dirksen, C; Hansen, DL; Holst, JJ; Jacobsen, SH; Jørgensen, NB; Kristiansen, VB; Madsbad, S; Naver, L; Worm, D1
Khan, SA; Nanduri, J; Prabhakar, NR; Wang, N1
Chen, Y; Cheng, J; He, S; Jin, X; Li, H; Lu, Y; Ren, Y; Wang, C; Wang, D; Wang, L; Zhao, J1
Basu, A; Basu, R; Carter, R; Cobelli, C; Dalla Man, C; Hinshaw, L; Johnson, M; Kudva, Y; Mallad, A; Schiavon, M; Sparacino, G1
Anselmino, M; Astiarraga, B; Baldi, S; Camastra, S; Ciociaro, D; Ferrannini, E; Gastaldelli, A; Holst, JJ; Mari, A; Muscelli, E; Nannipieri, M1
Ito, R; Matsuda-Nagasumi, K; Mori, I; Negoro, N; Takeuchi, K; Tsujihata, Y1
Itoh, N; Konishi, M; Mochiyama, T; Murata, Y; Nishio, K; Ohta, H; Shimada, M1
Carlson, OD; de Cabo, R; Doyle, ME; Egan, JM; Farhang, K; Fiori, JL; Gadkaree, SK; González-Mariscal, I; Kim, W; Krzysik-Walker, SM; Mattison, JA; Moaddel, R; Pearson, KJ; Sanghvi, M; Shin, YK1
Bojsen-Møller, KN; Dirksen, C; Hansen, DL; Holst, JJ; Jacobsen, SH; Jørgensen, NB; Kristiansen, VB; Madsbad, S; Naver, LS; Worm, D1
Dent, SY; Hogan, MF; Lackey, D; Montminy, M; Olefsky, J; Ravnskjaer, K; Tora, L1
Anselmino, M; Baldi, S; Barsotti, E; Bellini, R; Berta, R; Camastra, S; Colligiani, D; Ferrannini, E; Guarino, D; Mari, A; Moriconi, D; Nannipieri, M1
Bhat, VK; Flatt, PR; Gault, VA; Irwin, N1
Berglund, ED; Elmquist, JK; Kim, MH; Lee, CE; Liu, C; Liu, T; Sohn, JW; Vianna, CR; Williams, KW; Xu, Y1
Bagnoli, F; Conte, ML; Pasqui, L; Sestini, F; Tomasini, B; Vodo, F; Vodo, S; Vodo, Z1
Bahekar, R; Dhanesha, N; Jain, M; Joharapurkar, A; Kshirsagar, S; Patel, K; Patel, V; Shah, G1
Brüssow, KP; Görs, S; Hammon, HM; Lang, IS; Metges, CC; Nürnberg, G; Otten, W; Rehfeldt, C; Weitzel, JM1
Bae, JC; Choi, DW; Choi, SH; Heo, JS; Jin, SM; Kim, JH; Kim, KW; Lee, MK; Lee, MS; Suh, S1
Björnholm, M; Chibalin, AV; Deshmukh, AS; Garcia-Roves, PM; Holmström, MH; Jiang, LQ; Sjögren, RJ; Vieira, E; Zachariah Tom, R; Zierath, JR1
Beglinger, C; Bernsmeier, C; Blaser, LS; Heim, MH; Jeker, L; Meyer-Gerspach, AC; Steinert, RE1
Bagger, JI; Hansen, T; Holst, JJ; Knop, FK; Pedersen, O; Vilsbøll, T; Østoft, SH1
Aw, DK; Sinha, RA; Xie, SY; Yen, PM1
Briscoe, CP; Chon, S; Leonard, J; Ma, JY; Polidori, D; Suckow, AT; Yan, W1
Bianchi, L; Bonaventura, A; D'Angelo, A; Derosa, G; Fogari, E; Maffioli, P; Romano, D1
de Oliveira, Mda S; Geloneze, B; Novaes, FS; Pareja, JC; Tambascia, MA; Vasques, AC1
Han, W; Lach, S; Mulvey, T; Petersen, N; Phillips, A; Shepherd, PR; Smith, GC; Wang, MW; Xiu, P; Zhang, ZY1
Beglinger, C; Beglinger, S; Drewe, J; Graf, S; Gutzwiller, JP; Meyer-Gerspach, AC; Zumsteg, U1
Gu, JJ; Hou, LQ; Liu, YH; Zhao, TY1
Hirshberg, B; Iqbal, N; Lu, J; Sjöstrand, M1
Flatt, PR; Moffett, RC; Thorens, B; Vasu, S1
Bowe, JE; Franklin, ZJ; Hauge-Evans, AC; Jones, PM; King, AJ; Persaud, SJ1
Basu, A; Basu, R; Bharucha, AE; Carter, RE; Cobelli, C; Hinshaw, L; Kudva, YC; Mallad, A; Man, CD; Schiavon, M1
Allister, EM; Cai, EP; Gaisano, HY; Luk, CT; Schroer, SA; Shi, SY; Wang, L; Wheeler, MB; Woo, M1
Bokhari, S; Emmerson, P; Gupta, A; Meyer, C; Plummer, E1
Pellitero, S; Puig-Domingo, M1
Baur, JA; Becker, LB; Guan, Y; Reilly, PM; Sims, CA; Wang, H; Widlund, AL1
De Jesus, DF; Dirice, E; Hu, J; Kahraman, S; Kulkarni, RN1
Nakamura, S; Nakazato, M; Sakoda, H; Tsubouchi, C; Tsuchimochi, W; Ueno, H; Yamashita, E1
Abdulla, H; Atherton, PJ; Idris, I; Phillips, B; Smith, K; Wilkinson, D1
Bahekar, R; Jain, MR; Joharapurkar, AA; Kshirsagar, SG; Patel, KN; Patel, V; Srivastava, BK1
Baretić, M; Troskot, R1
Brandt, C; Galle, P; Gehl, J; Hansen, JB; Hansen, RH; Hojman, P; Mandrup-Poulsen, T; Olsen, CH; Pedersen, BK1
Anzueto, DG; Blanco, CL; DeFronzo, RA; Gastaldelli, A; Johnson, MC; Leland, MM; Liang, H; McCurnin, DC; McGill-Vargas, LL; Musi, N; Seidner, SR1
Gyldenløve, M; Holst, JJ; Knop, FK; Skov, L; Storgaard, H; Vilsbøll, T1
Flatt, PR; Moffett, RC; Vasu, S1
Bolze, S; Fouqueray, P; Mari, A; Pacini, G; Roden, M1
Eguchi, H; Fujita, Y; Imagawa, A; Iwahashi, H; Kozawa, J; Nagano, H; Okita, K; Shimomura, I; Uno, S; Yoneda, S; Yoshikawa, A1
Bhonde, RR; Chalasani, M; Ganneru, S; Malakapalli, V; Nappanveettil, G; Singh, H; Venkatesan, V1
Bojsen-Møller, KN1
Abderrahmani, A; Beaucamps, C; Bonner, C; Delalleau, N; Deprez, B; Gmyr, V; Kerr-Conte, J; Malaisse, WJ; Moerman, E; Pattou, F; Popescu, I; Queniat, G; Sener, A; Staels, B; Thévenet, J1
Ahmed, L; Bantle, JP; Bessler, M; Billington, CJ; Connett, JE; Ikramuddin, S; Inabnet, WB; Korner, J; Nguyen, KT; Thomas, A; Vella, A; Wang, Q1
Cho, WK; Jung, MH; Park, MS; Park, SH; Suh, BK1
Chang, BC; Chen, LM; Ren, HZ; Shan, CY; Wang, Y; Xu, YG; Yang, JH; Yang, YH; Zheng, MY1
Lautt, WW; Macedo, MP; Patarrão, RS1
Chan, CB; Han, W; Hashemi, Z; Jin, A; Li, L; Ozga, J; Yang, H; Yang, K1
Andreassen, KV; Gydesen, S; Henriksen, K; Hjuler, ST; Karsdal, MA1
Chang, B; Chen, L; Ren, H; Shan, C; Wang, Y; Xu, Y; Yang, J; Yang, Y; Zheng, M1
Bindels, LB; Burkart, V; Hartmann, B; Henrich, B; Holst, JJ; Hwang, JH; Kolb, H; MacKenzie, C; Martinez, I; Nowotny, B; Nowotny, P; Pacini, G; Roden, M; Schloot, NC; Simon, MC; Stehle, P; Strassburger, K; Walter, J; Zivehe, F1
Flatt, PR; Gault, VA; Irwin, N; Pathak, NM; Pathak, V1
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Kahn, CR; Neville, DM; Roth, J1
Bates, RW; Garrison, MM; Goldfine, ID; Kahn, CR; Neville, DM; Roth, J1
Dash, RJ; Gupta, PR; Rastogi, GK; Sinha, MK; Wahi, PL1
Yen, SS1
Danforth, E; Sims, EA1
Mosin, VI1
Späth, G1
Milner, RD1
Andreani, D; Fallucca, F; Iavicoli, M; Menzinger, G; Tamburrano, G1
Forsham, PH; Grodsky, GM; Karam, JH1
Brill, SJ; Chabner, BA; Felig, P1
Jungers, P; Kleinknecht, D; Laudat, MH; Laudat, P; Strauch, G1
Glasgow, AM1
Jordan, PH; Kahil, ME; McIlhaney, GR1
Kuroda, K; Matsuyama, T; Shima, K1
Bubnova, MM; Kniazev, IuA1

Reviews

99 review(s) available for glucagon and Insulin Resistance

ArticleYear
Pathways of Glucagon Secretion and Trafficking in the Pancreatic Alpha Cell: Novel Pathways, Proteins, and Targets for Hyperglucagonemia.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Biomarkers; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Secreting Cells; Humans; Hyperglycemia; Insulin Resistance; Signal Transduction

2021
Physiological significance of bistable circuit design in metabolic homeostasis: role of integrated insulin-glucagon signalling network.
    Molecular biology reports, 2022, Volume: 49, Issue:6

    Topics: Blood Glucose; Diabetes Mellitus, Type 2; Glucagon; Homeostasis; Humans; Insulin; Insulin Resistance; Signal Transduction

2022
Type 3 Diabetes and Its Role Implications in Alzheimer's Disease.
    International journal of molecular sciences, 2020, Apr-30, Volume: 21, Issue:9

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Blood Glucose; Brain; Diabetes Complications; Diabetes Mellitus; Disease Susceptibility; Glucagon; Glucose; Humans; Insulin; Insulin Resistance; Signal Transduction

2020
Glucose effectiveness: Lessons from studies on insulin-independent glucose clearance in mice.
    Journal of diabetes investigation, 2021, Volume: 12, Issue:5

    Topics: Administration, Intravenous; Adult; Aged; Animals; Biological Transport; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose; Homeostasis; Humans; Incretins; Insulin; Insulin Resistance; Insulin Secretion; Male; Mice; Middle Aged

2021
Glucose-lowering action through targeting islet dysfunction in type 2 diabetes: Focus on dipeptidyl peptidase-4 inhibition.
    Journal of diabetes investigation, 2021, Volume: 12, Issue:7

    Topics: Asia, Eastern; Asian People; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Glucagon; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Metformin

2021
The role of glucagon in weight loss-mediated metabolic improvement: a systematic review and meta-analysis.
    Obesity reviews : an official journal of the International Association for the Study of Obesity, 2018, Volume: 19, Issue:2

    Topics: Bariatric Surgery; Blood Glucose; Diet, Reducing; Fasting; Glucagon; Humans; Insulin Resistance; Obesity; Observational Studies as Topic; Weight Loss

2018
[Role of Paradoxical Hypersecretion of Glucagon in the Pathogenesis of Type 2 Diabetes Mellitus].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2018, Jun-28, Volume: 40, Issue:3

    Topics: Diabetes Mellitus, Type 2; Glucagon; Humans; Insulin; Insulin Resistance

2018
The Liver-α-Cell Axis and Type 2 Diabetes.
    Endocrine reviews, 2019, 10-01, Volume: 40, Issue:5

    Topics: Amino Acids; Animals; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Secreting Cells; Glucose; Humans; Insulin; Insulin Resistance; Liver

2019
Cell Autonomous Dysfunction and Insulin Resistance in Pancreatic α Cells.
    International journal of molecular sciences, 2019, Jul-28, Volume: 20, Issue:15

    Topics: Diabetes Mellitus, Type 2; Glucagon; Glucagon-Secreting Cells; Glucose; Humans; Insulin; Insulin Resistance; Liver

2019
Type 2 diabetes and the evolving paradigm in glucose regulation.
    The American journal of managed care, 2013, Volume: 19, Issue:3 Suppl

    Topics: Adipocytes; Appetite; Brain; Diabetes Mellitus, Type 2; Fasting; Fatty Acids, Nonesterified; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Glucose; Humans; Insulin Resistance; Insulin-Secreting Cells; Kidney; Liver; Muscle, Skeletal; Obesity; Sodium-Glucose Transport Proteins

2013
Metabolic phenotyping guidelines: assessing glucose homeostasis in rodent models.
    The Journal of endocrinology, 2014, Volume: 222, Issue:3

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Fasting; Female; Glucagon; Glucose; Glucose Tolerance Test; Guidelines as Topic; Homeostasis; Humans; Insulin; Insulin Resistance; Male; Mice; Phenotype; Pregnancy; Pregnancy in Diabetics; Rats; Somatostatin

2014
[New therapies for type 2 diabetes mellitus].
    Medicina clinica, 2015, Jun-22, Volume: 144, Issue:12

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Anti-Obesity Agents; Diabetes Mellitus, Type 2; Diacylglycerol O-Acyltransferase; Dipeptidyl Peptidase 4; Drug Therapy, Combination; Drugs, Investigational; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucokinase; Gluconeogenesis; Glucose; Humans; Hypoglycemic Agents; Incretins; Insulin Resistance; Insulin, Long-Acting; Molecular Targeted Therapy; Obesity; Phosphofructokinase-2; Sodium-Glucose Transport Proteins; Weight Loss

2015
Physiological mechanisms of action of incretin and insulin in regulating skeletal muscle metabolism.
    Current diabetes reviews, 2014, Volume: 10, Issue:5

    Topics: Blood Flow Velocity; Blood Glucose; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose; Homeostasis; Humans; Hyperglycemia; Hypoglycemic Agents; Incretins; Insulin; Insulin Resistance; Microcirculation; Muscle, Skeletal

2014
How to fight obesity with antidiabetic drugs: targeting gut or kidney?
    Minerva endocrinologica, 2015, Volume: 40, Issue:1

    Topics: Anti-Obesity Agents; Bariatric Surgery; Biological Transport; Clinical Trials as Topic; Comorbidity; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Exenatide; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glucose; Glycosuria; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Kidney Tubules, Proximal; Microvilli; Multicenter Studies as Topic; Obesity; Peptides; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Venoms; Weight Loss

2015
Mechanisms of improved glycaemic control after Roux-en-Y gastric bypass.
    Danish medical journal, 2015, Volume: 62, Issue:4

    Topics: Anastomosis, Roux-en-Y; Blood Glucose; Body Mass Index; Denmark; Female; Follow-Up Studies; Gastric Bypass; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin Resistance; Insulin-Secreting Cells; Male; Obesity, Morbid; Quality of Life; Treatment Outcome; Weight Loss

2015
Contribution of the distal small intestine to metabolic improvement after bariatric/metabolic surgery: Lessons from ileal transposition surgery.
    Journal of diabetes investigation, 2016, Volume: 7 Suppl 1

    Topics: Animals; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Eating; Endotoxemia; Enteroendocrine Cells; Gastric Bypass; Gastrointestinal Microbiome; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Ileum; Insulin; Insulin Resistance; Insulin Secretion; Rats

2016
An overview of incretin hormones.
    The Journal of family practice, 2008, Volume: 57, Issue:9 Suppl

    Topics: Blood Glucose; Diabetes Mellitus, Type 2; Glucagon; Humans; Incretins; Insulin Resistance; Insulin-Secreting Cells

2008
Growth factor control of pancreatic islet regeneration and function.
    Pediatric diabetes, 2009, Volume: 10, Issue:1

    Topics: Cell Division; Cellular Senescence; Glucagon; Growth Substances; Humans; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Regeneration

2009
Current and emerging therapies: an overview of incretin-based therapy in the management of type 2 diabetes.
    Journal of the American Academy of Nurse Practitioners, 2008, Volume: 20 Suppl 1

    Topics: Administration, Oral; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Disease Progression; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Incretins; Insulin Resistance; Middle Aged; Nurse Practitioners; Patient Selection; Primary Health Care

2008
Clinical review: Is lack of recombinant growth hormone (GH)-releasing hormone in the United States a setback or time to consider glucagon testing for adult GH deficiency?
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:8

    Topics: Arginine; Glucagon; Growth Hormone-Releasing Hormone; Guidelines as Topic; Human Growth Hormone; Humans; Insulin Resistance; Recombinant Proteins

2009
Pathophysiology of type 2 diabetes: targeting islet cell dysfunction.
    The Journal of the American Osteopathic Association, 2010, Volume: 110, Issue:3 Suppl 2

    Topics: Blood Glucose; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Disease Progression; Endocrine Cells; Genetic Predisposition to Disease; Global Health; Glucagon; Glucose; Humans; Incidence; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Risk Assessment

2010
Pro-insulin, C peptide, glucagon, adiponectin, TNF alpha, AMPK: neglected players in type 2 diabetes mellitus.
    The Journal of the Association of Physicians of India, 2010, Volume: 58

    Topics: Adipocytes; Adiponectin; AMP-Activated Protein Kinases; Biomarkers; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Glucagon; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Tumor Necrosis Factor-alpha

2010
Pathophysiology of prediabetes.
    The Medical clinics of North America, 2011, Volume: 95, Issue:2

    Topics: Blood Glucose; Diabetes Mellitus, Type 2; Glucagon; Glucose; Humans; Insulin Resistance; Insulin-Secreting Cells; Lipids; Liver; Prediabetic State; Risk Factors

2011
Type 2 diabetes across generations: from pathophysiology to prevention and management.
    Lancet (London, England), 2011, Jul-09, Volume: 378, Issue:9786

    Topics: Adipose Tissue; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Diabetes, Gestational; Diabetic Retinopathy; Epigenesis, Genetic; Female; Fetal Development; Genetic Predisposition to Disease; Glucagon; Glucagon-Like Peptide 1; Homeostasis; Humans; Incretins; Insulin Resistance; Insulin-Secreting Cells; Life Style; Liver; Muscle, Skeletal; Myocardium; Obesity; Prediabetic State; Pregnancy

2011
[Central insulin action and resistance in regulating diverse functions].
    Nihon rinsho. Japanese journal of clinical medicine, 2011, Volume: 69 Suppl 1

    Topics: Appetite Regulation; Brain; Glucagon; Gluconeogenesis; Humans; Insulin; Insulin Resistance; Learning; Liver

2011
[Glucagon and glucagon-like peptides the role in control glucose homeostasis. Part I].
    Pediatric endocrinology, diabetes, and metabolism, 2011, Volume: 17, Issue:4

    Topics: Blood Glucose; Energy Metabolism; Glucagon; Glucagon-Like Peptide 1; Glucose; Homeostasis; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans

2011
Minireview: The role of the autonomic nervous system in mediating the glucagon response to hypoglycemia.
    Endocrinology, 2012, Volume: 153, Issue:3

    Topics: Animals; Autoimmunity; Autonomic Nervous System; Central Nervous System; Diabetes Mellitus; Diabetes Mellitus, Type 1; Gene Expression Regulation; Glucagon; Glucose; Humans; Hypoglycemia; Insulin Resistance; Islets of Langerhans; Models, Biological; Peripheral Nervous System

2012
Glucagon and cyclic AMP: time to turn the page?
    Current diabetes reviews, 2012, Volume: 8, Issue:5

    Topics: Adipose Tissue; Biological Transport; Cyclic AMP; Female; Glucagon; Humans; Insulin; Insulin Resistance; Liver; Male; Myocardium; Phosphoenolpyruvate Carboxykinase (ATP); Pyruvate Kinase; Signal Transduction

2012
Insulin sensitivity and secretion modifications after bariatric surgery.
    Journal of endocrinological investigation, 2012, Volume: 35, Issue:7

    Topics: Animals; Bariatric Surgery; Body Mass Index; Diabetes Mellitus, Type 2; Gastric Mucosa; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Humans; Incretins; Insulin Resistance; Insulin-Secreting Cells; Intestinal Mucosa; Obesity, Morbid

2012
Insulin resistance in type 2 diabetic youth.
    Current opinion in endocrinology, diabetes, and obesity, 2012, Volume: 19, Issue:4

    Topics: Adolescent; Body Mass Index; C-Peptide; Child; Diabetes Mellitus, Type 2; Exercise Tolerance; Female; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Metformin; Obesity; Phenotype; Young Adult

2012
The combination of insulin and GLP-1 analogues in the treatment of type 2 diabetes.
    The Netherlands journal of medicine, 2012, Volume: 70, Issue:10

    Topics: Blood Glucose; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin; Insulin Resistance; Treatment Outcome

2012
Dysglycaemia in the critically ill - significance and management.
    Diabetes, obesity & metabolism, 2013, Volume: 15, Issue:9

    Topics: Analysis of Variance; Biomarkers; Blood Glucose; Critical Illness; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Female; Glucagon; Glucagon-Like Peptide 1; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Risk Factors

2013
Preclinical developments in type 2 diabetes.
    Advanced drug delivery reviews, 2002, Nov-05, Volume: 54, Issue:9

    Topics: Acetyl-CoA Carboxylase; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Fatty Acids, Nonesterified; Glucagon; Glucagon-Like Peptide 1; I-kappa B Kinase; Insulin Resistance; Peptide Fragments; Protein Precursors; Protein Serine-Threonine Kinases

2002
Aging and insulin secretion.
    American journal of physiology. Endocrinology and metabolism, 2003, Volume: 284, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Intolerance; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Middle Aged; Nutrition Surveys; Peptide Fragments

2003
Insulin sensitisation in the treatment of Type 2 diabetes.
    Expert opinion on investigational drugs, 2003, Volume: 12, Issue:3

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adrenergic beta-3 Receptor Agonists; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Humans; Hydroxysteroid Dehydrogenases; Hypoglycemic Agents; Insulin; Insulin Resistance; Islets of Langerhans; Metformin; Peptide Fragments; Protein Precursors; Randomized Controlled Trials as Topic; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Thiazoles; Transcription Factors

2003
[Analogs of glucagon-like peptide-1 (GLP-1): an old concept as a new treatment of patients with diabetes mellitus type 2].
    Nederlands tijdschrift voor geneeskunde, 2004, Sep-25, Volume: 148, Issue:39

    Topics: Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Enzyme Inhibitors; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin Resistance; Peptide Fragments; Protein Precursors

2004
Islet adaptation to insulin resistance: mechanisms and implications for intervention.
    Diabetes, obesity & metabolism, 2005, Volume: 7, Issue:1

    Topics: Adaptation, Physiological; Animals; Blood Glucose; Cholinergic Agonists; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Metformin; Peptide Fragments; Protein Precursors; Sulfonylurea Compounds

2005
[Impaired hepatic glucose metabolism].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 2

    Topics: Glucagon; Glucose; Glucose Intolerance; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Insulin Resistance; Lipid Metabolism; Liver; Obesity; Postprandial Period

2005
The incretins: a link between nutrients and well-being.
    The British journal of nutrition, 2005, Volume: 93 Suppl 1

    Topics: Animals; Autonomic Nervous System; Blood Glucose; Dietary Fiber; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Homeostasis; Humans; Insulin; Insulin Resistance; Insulin Secretion; Intestinal Mucosa; Inulin; Mice; Peptide Fragments; Protein Precursors; Receptors, Gastrointestinal Hormone; Receptors, Glucagon

2005
Changes in insulin resistance following bariatric surgery: role of caloric restriction and weight loss.
    Obesity surgery, 2005, Volume: 15, Issue:4

    Topics: Biomarkers; Blood Glucose; Body Mass Index; Caloric Restriction; Diabetes Mellitus, Type 2; Energy Metabolism; Female; Gastric Bypass; Gastric Inhibitory Polypeptide; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin Resistance; Male; Obesity, Morbid; Peptide Fragments; Peptide Hormones; Prognosis; Protein Precursors; Treatment Outcome; Weight Loss

2005
Dipeptidyl peptidase IV inhibitors and diabetes therapy.
    Frontiers in bioscience : a journal and virtual library, 2008, Jan-01, Volume: 13

    Topics: Animals; Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Enzyme Inhibitors; Glucagon; Glucose; Homeostasis; Humans; Incretins; Insulin; Insulin Resistance; Models, Biological

2008
Abnormalities in glucose metabolism in patients with schizophrenia treated with atypical antipsychotic medications.
    The American journal of medicine, 2008, Volume: 121, Issue:2

    Topics: Animals; Antipsychotic Agents; Cannabinoid Receptor Modulators; Diabetes Mellitus; Ghrelin; Glucagon; Glucose Metabolism Disorders; Humans; Insulin; Insulin Resistance; Leptin; Schizophrenia

2008
Metabolic effects of sulfonylurea drugs. A review.
    Annals of clinical research, 1983, Volume: 15 Suppl 37

    Topics: Animals; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucose; Humans; Insulin; Insulin Resistance; Insulin Secretion; Liver; Somatostatin; Sulfonylurea Compounds

1983
New pharmacologic approaches to the treatment of diabetes.
    Special topics in endocrinology and metabolism, 1984, Volume: 6

    Topics: Carbohydrate Metabolism; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glucagon; Gluconeogenesis; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Pyrrolidines; Somatostatin; Sulfonylurea Compounds

1984
Advances in endocrine pharmacotherapeutics. Part--III.
    The Journal of the Association of Physicians of India, 1984, Volume: 32, Issue:11

    Topics: Adult; Child; Chronic Kidney Disease-Mineral and Bone Disorder; Female; Glucagon; Humans; Hyperparathyroidism; Hyperthyroidism; Hypoparathyroidism; Hypothyroidism; Insulin; Insulin Resistance; Osteomalacia; Pregnancy; Rickets; Somatostatin; Vitamin D

1984
Alterations of maternal metabolism in normal and diabetic pregnancies: differences in insulin-dependent, non-insulin-dependent, and gestational diabetes.
    American journal of obstetrics and gynecology, 1983, Jun-15, Volume: 146, Issue:4

    Topics: Blood Glucose; C-Peptide; Child; Circadian Rhythm; Female; Glucagon; Humans; Hydrocortisone; Insulin; Insulin Resistance; Lipoproteins, HDL; Maternal-Fetal Exchange; Placenta; Postpartum Period; Pregnancy; Pregnancy in Diabetics; Prolactin; Time Factors; Triglycerides; Uterus

1983
[Anomalies of glycoregulation in alcoholic cirrhosis of the liver].
    Journees annuelles de diabetologie de l'Hotel-Dieu, 1984

    Topics: Adipose Tissue; Blood Glucose; Carbohydrate Metabolism; Glucagon; Gluconeogenesis; Glucose Tolerance Test; Homeostasis; Humans; Insulin; Insulin Resistance; Insulin Secretion; Liver; Liver Cirrhosis, Alcoholic; Monocytes; Receptor, Insulin

1984
The relationship between the hyperplastic pancreatic islet and insulin insensitivity in obesity.
    Acta diabetologica latina, 1981, Volume: 18, Issue:1

    Topics: Adipose Tissue; Alloxan; Animals; Glucagon; Glucose; Humans; Hyperplasia; Insulin; Insulin Resistance; Islets of Langerhans; Liver; Mice; Mice, Obese; Microscopy, Electron; Muscles; Obesity; Receptor, Insulin; Streptozocin

1981
[Endocrine changes in hepatic cirrhosis].
    Recenti progressi in medicina, 1981, Volume: 71, Issue:3

    Topics: Adrenal Cortex Hormones; Carbohydrate Metabolism; Endocrine Glands; Gastrins; Glucagon; Glucose Tolerance Test; Gonadal Steroid Hormones; Growth Hormone; Hormones; Humans; Insulin; Insulin Resistance; Liver Cirrhosis; Prolactin; Thyroid Hormones

1981
Uremia and the liver. III. Uremia and hepatic metabolism of carbohydrates, lipids, and proteins.
    Nephron, 1981, Volume: 29, Issue:1-2

    Topics: Amino Acids; Animals; Carbohydrate Metabolism; Cholesterol; Glucagon; Gluconeogenesis; Glucose Tolerance Test; Humans; Insulin Resistance; Lipid Metabolism; Lipoproteins, VLDL; Liver; Liver Glycogen; Protein Biosynthesis; Proteins; Triglycerides; Urea; Uremia

1981
[Maternal glucose tolerance along pregnancy (author's transl)].
    Pathologie-biologie, 1982, Volume: 30, Issue:1

    Topics: Amino Acids; Energy Metabolism; Estrogens; Female; Glucagon; Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Liver; Maternal-Fetal Exchange; Placental Lactogen; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Progesterone; Receptor, Insulin

1982
[Active chronic hepatitis and insulin resistance: possible role of glucagon, GH and free fatty acids].
    Giornale di clinica medica, 1981, Volume: 62, Issue:12

    Topics: Adult; Arginine; Carbohydrate Metabolism; Fatty Acids, Nonesterified; Glucagon; Glucose; Glucose Tolerance Test; Growth Hormone; Hepatitis; Humans; Insulin; Insulin Resistance; Male; Middle Aged

1981
Metabolic effects of insulin-like growth factor-I: a focus on insulin sensitivity.
    Metabolism: clinical and experimental, 1995, Volume: 44, Issue:10 Suppl 4

    Topics: Animals; Diabetes Mellitus; Glucagon; Growth Hormone; Humans; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Like Growth Factor I; Metabolism

1995
[Factors with insulin-like effects: IGF-I and GLP-1].
    Vnitrni lekarstvi, 1995, Volume: 41, Issue:9

    Topics: Blood Glucose; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin Resistance; Insulin-Like Growth Factor I; Pancreatic Hormones; Peptide Fragments; Peptides; Protein Precursors

1995
Glucose metabolism and liver cirrhosis.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 1995, Volume: 103, Issue:2

    Topics: Catecholamines; Chronic Disease; Diabetes Mellitus, Type 2; Fatty Acids; Glucagon; Glucose; Humans; Hyperglycemia; Hyperinsulinism; Insulin Resistance; Insulin-Like Growth Factor I; Liver Cirrhosis; Nutrition Disorders

1995
The genetics of non-insulin-dependent diabetes mellitus.
    Advances in genetics, 1995, Volume: 32

    Topics: Amyloid; Animals; Base Sequence; Carrier Proteins; Chromosome Mapping; Cloning, Molecular; Diabetes Mellitus, Type 2; DNA, Mitochondrial; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Glucagon; Glucagon-Like Peptide 1; Glucokinase; Glucose Transporter Type 4; Glycogen Synthase; Humans; Insulin; Insulin Resistance; Islet Amyloid Polypeptide; Molecular Sequence Data; Monosaccharide Transport Proteins; Muscle Proteins; Neoplasm Proteins; Peptide Fragments; Protein Precursors; Receptor, Insulin; Selection, Genetic; Tumor Suppressor Proteins

1995
[Insulin resistance: role in type 2 diabetes].
    Diabete & metabolisme, 1994, Volume: 20, Issue:3 Pt 2

    Topics: Diabetes Mellitus, Type 2; Fatty Acids; Glucagon; Glucose; Humans; Insulin Resistance; Liver; Muscle, Skeletal; Oxidation-Reduction

1994
Hormonal responses and future treatment of non-insulin-dependent diabetes mellitus (NIDDM).
    Journal of internal medicine, 1993, Volume: 234, Issue:2

    Topics: Animals; Diabetes Mellitus, Type 2; Glucagon; Humans; Insulin; Insulin Resistance; Insulin Secretion; Pancreatic Hormones; Prediabetic State; Somatostatin

1993
New treatments for patients with type 2 diabetes mellitus.
    Postgraduate medical journal, 1996, Volume: 72, Issue:853

    Topics: Amyloid; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Islet Amyloid Polypeptide; Peptide Fragments; Protein Precursors; Sulfonylurea Compounds

1996
New concepts in extracellular signaling for insulin action: the single gateway hypothesis.
    Recent progress in hormone research, 1997, Volume: 52

    Topics: Biological Transport; Endothelium, Vascular; Glucagon; Glucose; Humans; Insulin; Insulin Resistance; Signal Transduction

1997
Glucagon-like peptide-1 structure, function and potential use for NIDDM.
    Israel journal of medical sciences, 1997, Volume: 33, Issue:10

    Topics: Diabetes Mellitus, Type 2; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Peptide Fragments; Protein Precursors; Receptors, Glucagon

1997
Metabolic abnormalities in impaired glucose tolerance.
    Metabolism: clinical and experimental, 1997, Volume: 46, Issue:12 Suppl 1

    Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus; Glucagon; Glucose; Glucose Intolerance; Humans; Hyperglycemia; Insulin; Insulin Resistance; Middle Aged; Prevalence; Risk Factors; United States

1997
[Physiopathological fundamentals of type 2 diabetes].
    La Revue du praticien, 1999, Jan-01, Volume: 49, Issue:1

    Topics: Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Glucagon; Gluconeogenesis; Humans; Insulin; Insulin Resistance; Obesity

1999
Aspects of secretion and actions of amylin: interplay between amylin and other hormones.
    Journal of endocrinological investigation, 1999, Volume: 22, Issue:5 Suppl

    Topics: Amyloid; Gastric Emptying; Glucagon; Hormones; Human Growth Hormone; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islet Amyloid Polypeptide; Satiety Response

1999
Present and potential future use of gene therapy for the treatment of non-insulin dependent diabetes mellitus (Review).
    International journal of molecular medicine, 1999, Volume: 4, Issue:6

    Topics: Adult; Animals; Antigens, Neoplasm; Biomarkers, Tumor; Blood Glucose; Cell Transplantation; Diabetes Mellitus, Type 2; Gene Expression Regulation; Genes, Synthetic; Genetic Therapy; Genetic Vectors; Glucagon; Glucagon-Like Peptide 1; Glucokinase; Glucose Transporter Type 2; Homeodomain Proteins; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Lectins, C-Type; Mice; Middle Aged; Monosaccharide Transport Proteins; Muscle Contraction; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pancreatitis-Associated Proteins; Peptide Fragments; Promoter Regions, Genetic; Protein Precursors; Proteins; Rats; Trans-Activators

1999
[Hepatogenic diabetes--the current concepts of its pathophysiology and therapy].
    Deutsche medizinische Wochenschrift (1946), 1999, Dec-17, Volume: 124, Issue:50

    Topics: Diabetes Mellitus; Diabetes Mellitus, Type 2; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Hypoglycemic Agents; Insulin Resistance; Liver; Liver Diseases; Peptide Fragments; Receptor, Insulin

1999
[Insulin resistance and liver].
    Nihon rinsho. Japanese journal of clinical medicine, 2000, Volume: 58, Issue:2

    Topics: Animals; Diabetes Mellitus; Glucagon; Glucose; Glycogen; Humans; Insulin; Insulin Resistance; Liver

2000
Impaired glucose tolerance: the irrepressible alpha-cell?
    Diabetes care, 2000, Volume: 23, Issue:5

    Topics: Female; Glucagon; Glucose Intolerance; Humans; Insulin Resistance; Islets of Langerhans

2000
The multifaceted potential of glucagon-like peptide-1 as a therapeutic agent.
    Minerva endocrinologica, 2002, Volume: 27, Issue:2

    Topics: Animals; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Administration Routes; Gastric Emptying; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Intestine, Small; Islets of Langerhans; Peptide Fragments; Protein Precursors; Rats; Receptors, Glucagon; Satiety Response; Signal Transduction

2002
[Isoglycemic blood interval and mechanism of its regulation: facts and hypotheses (a literature review)].
    Klinicheskaia laboratornaia diagnostika, 2001, Issue:3

    Topics: Adipocytes; Animals; Blood Glucose; Fatty Acids, Unsaturated; Glucagon; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Humans; Insulin; Insulin Resistance; Monocytes; Monosaccharide Transport Proteins; Muscle Proteins; Receptor, Insulin

2001
Impaired beta-cell and alpha-cell function in African-American children with type 2 diabetes mellitus--"Flatbush diabetes".
    Journal of pediatric endocrinology & metabolism : JPEM, 2002, Volume: 15 Suppl 1

    Topics: Adolescent; Adult; Black People; Body Mass Index; C-Peptide; Child; Diabetes Mellitus, Type 2; Food; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Puberty

2002
The role of insulin in hypertriglyceridemia.
    Nutrition reviews, 1975, Volume: 33, Issue:7

    Topics: Dietary Carbohydrates; Dietary Fats; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hyperinsulinism; Hyperlipidemias; Insulin; Insulin Resistance; Lipoproteins, VLDL; Liver; Triglycerides

1975
Isolation and characterization of membrane drug receptors.
    Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques, 1976, Volume: 20

    Topics: Animals; Drug Tolerance; gamma-Aminobutyric Acid; Glucagon; Glycine; Humans; Insulin; Insulin Resistance; Membranes; Morphine; Receptor, Insulin; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Cholinergic; Receptors, Drug; Receptors, Opioid; Sodium; Substance-Related Disorders; Toxins, Biological

1976
Metabolic changes in pregnancy relevant to diabetes mellitus.
    Postgraduate medical journal, 1979, Volume: 55, Issue:643

    Topics: Adult; Blood Glucose; Carbohydrate Metabolism; Female; Glucagon; Glucose Tolerance Test; Hemoglobin A; Humans; Insulin; Insulin Resistance; Pregnancy; Pregnancy in Diabetics; Proinsulin

1979
Insulin resistance in obesity: a critical analysis at enzyme level. A review.
    International journal of obesity, 1979, Volume: 3, Issue:4

    Topics: Adipose Tissue; Animals; Diabetes Mellitus; Glucagon; Gluconeogenesis; Humans; Hyperglycemia; Hyperinsulinism; Insulin Resistance; Lipolysis; Liver; Mice; Muscles; Obesity; Proteins; Rats

1979
[Methods for the characterization of glucose turnover and the peripheral insulin resistance in human prediabetic conditions].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1979, Oct-01, Volume: 34, Issue:19

    Topics: C-Peptide; Fatty Acids, Nonesterified; Glucagon; Glucose; Glycerol; Growth Hormone; Humans; Insulin Resistance; Liver; Prediabetic State; Tritium

1979
[Diabetes mellitus secondary to liver diseases. A review (author's transl)].
    Diabete & metabolisme, 1975, Volume: 1, Issue:3

    Topics: Diabetes Mellitus; Fatty Acids, Nonesterified; Glucagon; Growth Hormone; Humans; Hypertension, Portal; Hypokalemia; Insulin; Insulin Resistance; Liver Cirrhosis; Pancreatic Diseases

1975
[Insulin resistance and diabetic ketoacidosis].
    Journees annuelles de diabetologie de l'Hotel-Dieu, 1976

    Topics: Blood Glucose; Diabetic Ketoacidosis; Fatty Acids, Nonesterified; Glucagon; Humans; Hydrocortisone; Hypothermia; Insulin; Insulin Antibodies; Insulin Resistance; Ketone Bodies

1976
Evolving role of glucagon in human diabetes mellitus.
    Diabetes, 1975, Volume: 24, Issue:5

    Topics: Diabetes Mellitus; Glucagon; Glucose; Humans; Hyperglycemia; Insulin Antagonists; Insulin Resistance; Ketone Bodies; Liver

1975
Octreotide and diabetes: theoretical and experimental aspects.
    Metabolism: clinical and experimental, 1992, Volume: 41, Issue:9 Suppl 2

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Growth Hormone; Humans; Insulin Resistance; Insulin-Like Growth Factor I; Octreotide; Vascular Diseases

1992
[Hyperthyroidism and glucose metabolism].
    Journees annuelles de diabetologie de l'Hotel-Dieu, 1991

    Topics: Blood Glucose; Clinical Trials as Topic; Glucagon; Gluconeogenesis; Hyperthyroidism; Insulin; Insulin Resistance

1991
Aetiology of gestational diabetes.
    Bailliere's clinical obstetrics and gynaecology, 1991, Volume: 5, Issue:2

    Topics: Diabetes, Gestational; Female; Glucagon; Humans; Insulin; Insulin Resistance; Islets of Langerhans; Pregnancy

1991
The insulin-antagonistic effect of the counterregulatory hormones.
    Journal of internal medicine. Supplement, 1991, Volume: 735

    Topics: Animals; Catecholamines; Diabetes Mellitus, Type 1; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin Resistance; Reference Values; Stress, Physiological

1991
Experimental reduction of B-cell mass: implications for the pathogenesis of diabetes.
    Diabetes/metabolism reviews, 1986, Volume: 2, Issue:1-2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Arginine; Blood Glucose; Cyclic AMP; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Drug Synergism; Glucagon; Glucose; Glucose Tolerance Test; Histocytochemistry; Humans; Immunologic Techniques; In Vitro Techniques; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Pancreatectomy; Rats; Rats, Inbred Strains

1986
Insulin-antagonistic effects of counterregulatory hormones: clinical and mechanistic aspects.
    Diabetes/metabolism reviews, 1989, Volume: 5, Issue:6

    Topics: Animals; Catecholamines; Diabetes Mellitus; Glucagon; Homeostasis; Hormones; Humans; Insulin Antagonists; Insulin Resistance

1989
Glucose regulation in non-insulin-dependent diabetes mellitus. Interaction between pancreatic islets and the liver.
    The American journal of medicine, 1985, Aug-23, Volume: 79, Issue:2B

    Topics: Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Fatty Acids, Nonesterified; Feedback; Glucagon; Gluconeogenesis; Glucose; Glycogen; Homeostasis; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Liver; Somatostatin; Sulfonylurea Compounds

1985
Insulin-dependent diabetes mellitus: pathophysiology.
    Mayo Clinic proceedings, 1986, Volume: 61, Issue:10

    Topics: Autoimmune Diseases; Blood Glucose; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Diagnosis, Differential; Glucagon; Humans; Insulin; Insulin Resistance

1986
[Disturbances of glucose metabolism and its regulation in hepatopathies].
    Gastroenterologie clinique et biologique, 1985, Volume: 9, Issue:1

    Topics: Glucagon; Glucose; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Resistance; Insulin Secretion; Liver; Liver Diseases

1985
Is there an animal model for gestational diabetes?
    Diabetes, 1985, Volume: 34 Suppl 2

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Gestational Age; Glucagon; Glucose; Hydrocortisone; Insulin; Insulin Resistance; Islets of Langerhans; Mice; Pregnancy; Pregnancy in Diabetics; Progesterone; Rats

1985
Etiology and pathophysiology of gestational diabetes mellitus.
    Diabetes, 1985, Volume: 34 Suppl 2

    Topics: Alanine; Amino Acids; Blood Glucose; Dietary Proteins; Female; Glucagon; Glucose Tolerance Test; Humans; Hydrocortisone; Insulin; Insulin Resistance; Insulin Secretion; Monocytes; Pregnancy; Pregnancy in Diabetics; Proinsulin; Receptor, Insulin; Triglycerides

1985
On the decrease of glucose tolerance in pregnancy: studies of gastro-entero-pancreatic hormones and cortisol.
    Danish medical bulletin, 1985, Volume: 32, Issue:2

    Topics: Blood Glucose; Female; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Hormones; Glucagon; Humans; Hydrocortisone; Insulin; Insulin Resistance; Insulin Secretion; Pancreatic Polypeptide; Pregnancy; Pregnancy in Diabetics

1985
Islet-cell abnormalities in non-insulin-dependent diabetes mellitus.
    The American journal of medicine, 1985, Aug-23, Volume: 79, Issue:2B

    Topics: Alanine; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Dietary Proteins; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans

1985
Is glucose intolerance harmful for the uremic patient?
    Kidney international. Supplement, 1985, Volume: 17

    Topics: Amino Acids, Branched-Chain; Arteriosclerosis; Diabetes Mellitus; Diabetic Angiopathies; Glomerular Filtration Rate; Glucagon; Glucose; Glycated Hemoglobin; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Lipoproteins, VLDL; Renal Dialysis; Uremia

1985
Endocrine regulation of metabolic homeostasis during pregnancy.
    Clinical obstetrics and gynecology, 1973, Volume: 16, Issue:3

    Topics: Adipose Tissue; Amino Acids; Animals; Catecholamines; Endocrine Glands; Fatty Acids, Nonesterified; Female; Gastrointestinal Hormones; Glucagon; Glucocorticoids; Gluconeogenesis; Glucose; Growth Hormone; Homeostasis; Humans; Insulin; Insulin Resistance; Insulin Secretion; Lipid Metabolism; Maternal-Fetal Exchange; Metabolism; Muscles; Pancreas; Placental Hormones; Pregnancy

1973
Role of insulin in obesity.
    Israel journal of medical sciences, 1974, Volume: 10, Issue:10

    Topics: Adipose Tissue; Animals; Dietary Carbohydrates; Dietary Fats; Eating; Fatty Acids; Female; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypothalamus; Insulin; Insulin Resistance; Insulin Secretion; Obesity

1974
[Carbohydrate metabolism in liver diseases].
    Klinicheskaia meditsina, 1974, Volume: 52, Issue:2

    Topics: Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus; Fatty Acids, Nonesterified; Glucagon; Glucose; Glucose Tolerance Test; Growth Hormone; Hepatitis; Humans; Hyperglycemia; Hypoglycemia; Insulin; Insulin Resistance; Insulin Secretion; Liver; Liver Cirrhosis; Liver Diseases; Pancreatitis; Tolbutamide

1974
[Intensive medicine. Acute threatening metabolic disorders in diabetes mellitus].
    Munchener medizinische Wochenschrift (1950), 1972, Oct-27, Volume: 114, Issue:43

    Topics: Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus; Diabetic Coma; Diabetic Ketoacidosis; Diagnosis, Differential; Electrolytes; Emergencies; Glucagon; Glucose; Glycosuria; Humans; Hyperglycemia; Hypoglycemia; Infusions, Parenteral; Insulin; Insulin Resistance; Lactates; Mental Disorders; Neurologic Manifestations; Osmosis; Prognosis; Shock

1972
Insulin secretion in human protein-calorie deficiency.
    The Proceedings of the Nutrition Society, 1972, Volume: 31, Issue:2

    Topics: Blood Glucose; Chromium; Fatty Acids, Nonesterified; Glucagon; Glucose Tolerance Test; Growth Hormone; Humans; Infant; Infant Nutrition Disorders; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Kwashiorkor; Nutrition Disorders; Potassium Deficiency; Protein-Energy Malnutrition; Secretory Rate

1972
Insulin secretion in obesity: pseudodiabetes?
    The American journal of clinical nutrition, 1968, Volume: 21, Issue:12

    Topics: Age Factors; Animals; Diabetes Mellitus; Glucagon; Glucose; Humans; Hyperplasia; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans

1968

Trials

83 trial(s) available for glucagon and Insulin Resistance

ArticleYear
The sodium-glucose cotransporter 2 inhibitor ipragliflozin improves liver function and insulin resistance in Japanese patients with type 2 diabetes.
    Scientific reports, 2022, 02-03, Volume: 12, Issue:1

    Topics: Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucosides; Humans; Insulin; Insulin Resistance; Japan; Liver; Male; Middle Aged; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Time Factors; Treatment Outcome

2022
Effects of subcutaneous tirzepatide versus placebo or semaglutide on pancreatic islet function and insulin sensitivity in adults with type 2 diabetes: a multicentre, randomised, double-blind, parallel-arm, phase 1 clinical trial.
    The lancet. Diabetes & endocrinology, 2022, Volume: 10, Issue:6

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Insulins; Islets of Langerhans; Treatment Outcome

2022
Metformin Lowers Body Weight But Fails to Increase Insulin Sensitivity in Chronic Heart Failure Patients without Diabetes: a Randomized, Double-Blind, Placebo-Controlled Study.
    Cardiovascular drugs and therapy, 2021, Volume: 35, Issue:3

    Topics: Aged; Body Composition; Body Weight; Calorimetry, Indirect; Double-Blind Method; Female; Glucagon; Glycated Hemoglobin; Heart Failure; Humans; Insulin Resistance; Male; Metformin; Middle Aged; Mitochondria; Muscle, Skeletal; Oxygen Consumption; Stroke Volume

2021
Exercise Increases Insulin Sensitivity and Skeletal Muscle AMPK Expression in Systemic Lupus Erythematosus: A Randomized Controlled Trial.
    Frontiers in immunology, 2018, Volume: 9

    Topics: Adult; AMP-Activated Protein Kinases; Biopsy; Blood Glucose; Exercise; Female; Glucagon; Glucose Transporter Type 4; Humans; Insulin; Insulin Resistance; Lupus Erythematosus, Systemic; Male; Muscle, Skeletal; Phosphorylation; Signal Transduction

2018
Alpha cell function interacts with diet to modulate prediabetes and Type 2 diabetes.
    The Journal of nutritional biochemistry, 2018, Volume: 62

    Topics: Blood Glucose; Diabetes Mellitus, Type 2; Diet, Mediterranean; Disease-Free Survival; Female; Glucagon; Glucagon-Secreting Cells; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Middle Aged; Prediabetic State

2018
Basal glucagon hypersecretion and response to oral glucose load in prediabetes and mild type 2 diabetes.
    Endocrine journal, 2019, Aug-29, Volume: 66, Issue:8

    Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin Resistance; Male; Middle Aged; Prediabetic State; Severity of Illness Index; Young Adult

2019
Exaggerated release and preserved insulinotropic action of glucagon-like peptide-1 underlie insulin hypersecretion in glucose-tolerant individuals after Roux-en-Y gastric bypass.
    Diabetologia, 2013, Volume: 56, Issue:12

    Topics: Adult; Blood Glucose; Female; Gastric Bypass; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Male; Obesity, Morbid; Pancreas; Peptide Fragments; Postprandial Period; Treatment Outcome

2013
Comparison of vildagliptin and glimepiride: effects on glycaemic control, fat tolerance and inflammatory markers in people with type 2 diabetes.
    Diabetic medicine : a journal of the British Diabetic Association, 2014, Volume: 31, Issue:12

    Topics: Adamantane; Adiponectin; Aged; Biomarkers; Blood Glucose; C-Reactive Protein; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Dietary Fats; Double-Blind Method; Drug Therapy, Combination; Female; Glucagon; Glucose Clamp Technique; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipid Metabolism; Male; Metformin; Middle Aged; Nitriles; Proinsulin; Pyrrolidines; Sulfonylurea Compounds; Treatment Outcome; Triglycerides; Tumor Necrosis Factor-alpha; Vildagliptin

2014
Impaired incretin secretion and pancreatic dysfunction with older age and diabetes.
    Metabolism: clinical and experimental, 2014, Volume: 63, Issue:7

    Topics: Adiponectin; Adipose Tissue; Adult; Aged; Aging; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Down-Regulation; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Incretins; Insulin; Insulin Resistance; Insulin Secretion; Male; Middle Aged; Pancreas; Postprandial Period; Up-Regulation

2014
Effect of a test meal on meal responses of satiation hormones and their association to insulin resistance in obese adolescents.
    Obesity (Silver Spring, Md.), 2014, Volume: 22, Issue:9

    Topics: Adolescent; Body Mass Index; Child; Female; Gastrointestinal Hormones; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin; Insulin Resistance; Islet Amyloid Polypeptide; Male; Meals; Metabolic Syndrome; Pediatric Obesity; Postprandial Period; Satiation

2014
Saxagliptin improves glycemic control by modulating postprandial glucagon and C-peptide levels in Chinese patients with type 2 diabetes.
    Diabetes research and clinical practice, 2014, Volume: 105, Issue:2

    Topics: Adamantane; Asian People; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Drug Therapy, Combination; Fasting; Female; Glucagon; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Metformin; Middle Aged; Postprandial Period

2014
Glucose counterregulation in advanced type 2 diabetes: effect of β-adrenergic blockade.
    Diabetes care, 2014, Volume: 37, Issue:11

    Topics: Adrenergic beta-Antagonists; C-Peptide; Case-Control Studies; Cross-Over Studies; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Middle Aged; Single-Blind Method

2014
Imeglimin increases glucose-dependent insulin secretion and improves β-cell function in patients with type 2 diabetes.
    Diabetes, obesity & metabolism, 2015, Volume: 17, Issue:6

    Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucagon; Glucose Clamp Technique; Hepatobiliary Elimination; Humans; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Middle Aged; Triazines

2015
Preserved Insulin Secretory Capacity and Weight Loss Are the Predominant Predictors of Glycemic Control in Patients With Type 2 Diabetes Randomized to Roux-en-Y Gastric Bypass.
    Diabetes, 2015, Volume: 64, Issue:9

    Topics: Adiponectin; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Gastric Bypass; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Middle Aged; Obesity; Treatment Outcome; Weight Loss

2015
Intake of Lactobacillus reuteri improves incretin and insulin secretion in glucose-tolerant humans: a proof of concept.
    Diabetes care, 2015, Volume: 38, Issue:10

    Topics: Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Incretins; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Limosilactobacillus reuteri; Male; Middle Aged; Obesity; Oxidative Stress; Pilot Projects; Probiotics; Prospective Studies; Protein Precursors

2015
The structure of wheat bread influences the postprandial metabolic response in healthy men.
    Food & function, 2015, Volume: 6, Issue:10

    Topics: Bile Acids and Salts; Blood Glucose; Body Mass Index; Bread; Breath Tests; Carbon Dioxide; Cross-Over Studies; Gastric Inhibitory Polypeptide; Glucagon; Humans; Incretins; Insulin; Insulin Resistance; Male; Portion Size; Postprandial Period; Triticum; Young Adult

2015
Effect of meal composition on postprandial glucagon-like peptide-1, insulin, glucagon, C-peptide, and glucose responses in overweight/obese subjects.
    European journal of nutrition, 2017, Volume: 56, Issue:3

    Topics: Adolescent; Adult; Aged; Appetite; Blood Glucose; Body Mass Index; C-Peptide; Cross-Over Studies; Exercise; Female; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin; Insulin Resistance; Male; Meals; Mental Recall; Middle Aged; Obesity; Overweight; Postprandial Period; Young Adult

2017
Mechanisms of Action of Liraglutide in Patients With Type 2 Diabetes Treated With High-Dose Insulin.
    The Journal of clinical endocrinology and metabolism, 2016, Volume: 101, Issue:4

    Topics: Adipose Tissue; Adult; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucagon; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Liraglutide; Magnetic Resonance Imaging; Male; Middle Aged

2016
Mechanisms Regulating Insulin Response to Intragastric Glucose in Lean and Non-Diabetic Obese Subjects: A Randomized, Double-Blind, Parallel-Group Trial.
    PloS one, 2016, Volume: 11, Issue:3

    Topics: Adult; Blood Glucose; Body Mass Index; Body Weight; C-Peptide; Case-Control Studies; Diabetes Mellitus; Double-Blind Method; Female; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose; Humans; Incretins; Insulin; Insulin Resistance; Male; Middle Aged; Obesity; Young Adult

2016
Ghrelin Impairs Prandial Glucose Tolerance and Insulin Secretion in Healthy Humans Despite Increasing GLP-1.
    The Journal of clinical endocrinology and metabolism, 2016, Volume: 101, Issue:6

    Topics: Adult; Blood Glucose; Female; Gastric Inhibitory Polypeptide; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin; Insulin Resistance; Male; Peptide YY; Postprandial Period; Young Adult

2016
Exercise-Induced Secretion of FGF21 and Follistatin Are Blocked by Pancreatic Clamp and Impaired in Type 2 Diabetes.
    The Journal of clinical endocrinology and metabolism, 2016, Volume: 101, Issue:7

    Topics: Adult; Cross-Over Studies; Diabetes Mellitus, Type 2; Exercise; Fibroblast Growth Factors; Follistatin; Glucagon; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Male; Pancreas; Young Adult

2016
Dapagliflozin Enhances Fat Oxidation and Ketone Production in Patients With Type 2 Diabetes.
    Diabetes care, 2016, Volume: 39, Issue:11

    Topics: Adolescent; Adult; Aged; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Creatinine; Diabetes Mellitus, Type 2; Double-Blind Method; Enzyme Inhibitors; Glucagon; Glucosides; Humans; Insulin; Insulin Resistance; Ketones; Lipid Metabolism; Middle Aged; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Young Adult

2016
Ghrelin, leptin, and glycemic control after sleeve gastrectomy versus Roux-en-Y gastric bypass-results of a randomized clinical trial.
    Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2017, Volume: 13, Issue:2

    Topics: Adolescent; Adult; Blood Glucose; C-Peptide; Female; Gastrectomy; Gastric Bypass; Ghrelin; Glucagon; Glycated Hemoglobin; Homeostasis; Humans; Insulin Resistance; Laparoscopy; Leptin; Male; Middle Aged; Obesity, Morbid; Operative Time; Prospective Studies; Weight Loss; Young Adult

2017
Third Exposure to a Reduced Carbohydrate Meal Lowers Evening Postprandial Insulin and GIP Responses and HOMA-IR Estimate of Insulin Resistance.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: 3-Hydroxybutyric Acid; Aged; Blood Glucose; Dietary Carbohydrates; Energy Intake; Energy Metabolism; Fatty Acids, Nonesterified; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Homeostasis; Humans; Insulin; Insulin Resistance; Middle Aged; Postprandial Period; Sedentary Behavior

2016
Effects of gemigliptin, a dipeptidyl peptidase-4 inhibitor, on lipid metabolism and endotoxemia after a high-fat meal in patients with type 2 diabetes.
    Diabetes, obesity & metabolism, 2017, Volume: 19, Issue:3

    Topics: Adiponectin; Adult; Aged; Apolipoprotein B-100; Apolipoprotein B-48; Blood Glucose; C-Reactive Protein; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cross-Over Studies; Cytokines; Diabetes Mellitus, Type 2; Diet, High-Fat; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Endotoxemia; Endotoxins; Female; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin; Insulin Resistance; Interleukin-6; Lipid Metabolism; Male; Middle Aged; Piperidones; Postprandial Period; Pyrimidines; RNA, Messenger; Subcutaneous Fat, Abdominal; Transcriptome; Triglycerides; Tumor Necrosis Factor-alpha

2017
Effect of exenatide on postprandial glucose fluxes, lipolysis, and ß-cell function in non-diabetic, morbidly obese patients.
    Diabetes, obesity & metabolism, 2017, Volume: 19, Issue:3

    Topics: Adipose Tissue; Adult; Blood Glucose; Exenatide; Fasting; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Lipolysis; Liver; Male; Middle Aged; Obesity, Morbid; Peptides; Postprandial Period; Venoms

2017
KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:2

    Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Infusion Pumps; Insulin; Insulin Resistance; Ion Channel Gating; KATP Channels; Male; Middle Aged; Sulfonylurea Compounds

2009
Addition of n-3 fatty acids to a 4-hour lipid infusion does not affect insulin sensitivity, insulin secretion, or markers of oxidative stress in subjects with type 2 diabetes mellitus.
    Metabolism: clinical and experimental, 2009, Volume: 58, Issue:12

    Topics: Adult; Aged; Biomarkers; Body Composition; C-Peptide; Calorimetry, Indirect; Cross-Over Studies; Diabetes Mellitus, Type 2; Diet; Dinoprost; Double-Blind Method; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Fatty Acids, Omega-3; Female; Glucagon; Glucose Clamp Technique; Humans; Infusions, Intravenous; Insulin; Insulin Resistance; Isoprostanes; Male; Middle Aged; Oxidative Stress

2009
The impact of exercise training compared to caloric restriction on hepatic and peripheral insulin resistance in obesity.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:11

    Topics: Aged; Aged, 80 and over; Body Weight; Caloric Restriction; Exercise; Gas Chromatography-Mass Spectrometry; Glucagon; Humans; Insulin; Insulin Resistance; Liver; Middle Aged; Obesity; Overweight; Patient Selection; Weight Loss

2009
Early improvement in glycemic control after bariatric surgery and its relationships with insulin, GLP-1, and glucagon secretion in type 2 diabetic patients.
    Obesity surgery, 2011, Volume: 21, Issue:7

    Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Female; Gastric Bypass; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Obesity; Prospective Studies; Treatment Outcome; Weight Loss

2011
Acute peripheral metabolic effects of intraarterial leg infusion of somatostatin in healthy young men.
    The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:8

    Topics: Adult; Biopsy; Blood Glucose; C-Peptide; Gene Expression; Glucagon; Glucose Clamp Technique; GTPase-Activating Proteins; Human Growth Hormone; Humans; Hyperinsulinism; Infusions, Intra-Arterial; Insulin Resistance; Insulin-Like Growth Factor I; Leg; Lipids; Male; Muscle, Skeletal; Somatostatin; STAT5 Transcription Factor; Suppressor of Cytokine Signaling Proteins; Young Adult

2011
Effects of dietary protein on lipid metabolism in high fructose fed humans.
    Clinical nutrition (Edinburgh, Scotland), 2012, Volume: 31, Issue:2

    Topics: Blood Glucose; Calorimetry, Indirect; Cross-Over Studies; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Energy Metabolism; Fatty Acids, Nonesterified; Fructose; Glucagon; Humans; Insulin; Insulin Resistance; Lipid Metabolism; Male; Postprandial Period; Triglycerides; Young Adult

2012
Impaired incretin-induced amplification of insulin secretion after glucose homeostatic dysregulation in healthy subjects.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:4

    Topics: Adult; Blood Glucose; C-Peptide; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Clamp Technique; Glucose Intolerance; Glucose Tolerance Test; Humans; Incretins; Infusions, Intravenous; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Kinetics; Male; Severity of Illness Index; Young Adult

2012
Metabolic effects of short-term GLP-1 treatment in insulin resistant heart failure patients.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2012, Volume: 120, Issue:5

    Topics: Blood Glucose; Calorimetry, Indirect; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Fatty Acids, Nonesterified; Glucagon; Glucagon-Like Peptide 1; Glucose Clamp Technique; Glucose Tolerance Test; Heart Failure; Humans; Insulin; Insulin Resistance; Male; Middle Aged

2012
Acute and long-term effects of Roux-en-Y gastric bypass on glucose metabolism in subjects with Type 2 diabetes and normal glucose tolerance.
    American journal of physiology. Endocrinology and metabolism, 2012, Jul-01, Volume: 303, Issue:1

    Topics: Adult; Body Mass Index; C-Peptide; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Gastric Bypass; Glucagon; Glucagon-Like Peptide 1; Glucose; Humans; Hyperglycemia; Insulin Resistance; Insulin-Secreting Cells; Male; Middle Aged; Obesity; Obesity, Morbid; Postprandial Period; Time Factors

2012
Effects of a combination of sitagliptin plus metformin vs metformin monotherapy on glycemic control, β-cell function and insulin resistance in type 2 diabetic patients.
    Diabetes research and clinical practice, 2012, Volume: 98, Issue:1

    Topics: Blood Glucose; C-Peptide; C-Reactive Protein; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Exercise; Fasting; Female; Glucagon; Glucose Clamp Technique; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Insulin-Secreting Cells; Italy; Male; Metformin; Middle Aged; Pyrazines; Sitagliptin Phosphate; Treatment Outcome; Triazoles

2012
The effect of a bile acid sequestrant on glucose metabolism in subjects with type 2 diabetes.
    Diabetes, 2013, Volume: 62, Issue:4

    Topics: Allylamine; Anticholesteremic Agents; Blood Glucose; C-Peptide; Colesevelam Hydrochloride; Diabetes Mellitus, Type 2; Double-Blind Method; Fasting; Female; Glucagon; Glucagon-Like Peptide 1; Glucose; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Postprandial Period

2013
Fibroblast growth factor 21 mediates specific glucagon actions.
    Diabetes, 2013, Volume: 62, Issue:5

    Topics: Adult; Animals; Anti-Obesity Agents; Cells, Cultured; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Fibroblast Growth Factors; Glucagon; HEK293 Cells; Hepatocytes; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Mice; Mice, Knockout; Mice, Mutant Strains; Molecular Targeted Therapy; Obesity; Peptides; Rats; Receptors, Glucagon; Recombinant Proteins

2013
Glucagon-like peptide-1 augments insulin-mediated glucose uptake in the obese state.
    The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:8

    Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Fatty Acids, Nonesterified; Female; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Obesity; Peptide Fragments; Protein Precursors

2002
Preferential stimulation of abdominal subcutaneous lipolysis after prednisolone exposure in humans.
    Obesity research, 2002, Volume: 10, Issue:8

    Topics: Abdomen; Adipose Tissue; Adult; Blood Glucose; C-Peptide; Calorimetry, Indirect; Cross-Over Studies; Double-Blind Method; Energy Metabolism; Fasting; Fatty Acids, Nonesterified; Femur; Glucagon; Glycerol; Human Growth Hormone; Humans; Insulin; Insulin Resistance; Lipolysis; Male; Microdialysis; Placebos; Prednisolone

2002
Effects of 1-mo bolus subcutaneous administration of exendin-4 in type 2 diabetes.
    American journal of physiology. Endocrinology and metabolism, 2003, Volume: 284, Issue:6

    Topics: Aged; Blood Glucose; Body Composition; C-Peptide; Diabetes Mellitus, Type 2; Exenatide; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glucose Clamp Technique; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Insulin Resistance; Islets of Langerhans; Male; Middle Aged; Peptides; Venoms

2003
Insulin secretion and cellular glucose metabolism after prolonged low-grade intralipid infusion in young men.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:6

    Topics: Adult; Area Under Curve; Blood Glucose; C-Peptide; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Glucagon; Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Male; Oxidation-Reduction

2003
Metabolic and endocrine effects of treatment with peroral or transdermal oestrogens in conjunction with peroral cyproterone acetate in women with polycystic ovary syndrome.
    European journal of endocrinology, 2004, Volume: 150, Issue:2

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Analysis of Variance; Blood Glucose; Contraceptive Agents; Cyproterone Acetate; Drug Combinations; Estradiol; Female; Glucagon; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Polycystic Ovary Syndrome

2004
One week's treatment with the long-acting glucagon-like peptide 1 derivative liraglutide (NN2211) markedly improves 24-h glycemia and alpha- and beta-cell function and reduces endogenous glucose release in patients with type 2 diabetes.
    Diabetes, 2004, Volume: 53, Issue:5

    Topics: Circadian Rhythm; Cross-Over Studies; Delayed-Action Preparations; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Administration Schedule; Female; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glucose; Hormones; Humans; Hypoglycemic Agents; Insulin Resistance; Islets of Langerhans; Liraglutide; Male; Middle Aged

2004
Insulin secretion in lipodystrophic HIV-infected patients is associated with high levels of nonglucose secretagogues and insulin resistance of beta-cells.
    American journal of physiology. Endocrinology and metabolism, 2004, Volume: 287, Issue:4

    Topics: Adipose Tissue; Adult; Alanine; Anthropometry; Blood Glucose; Body Composition; Body Mass Index; C-Peptide; Feedback; Glucagon; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Triglycerides

2004
Glucagon-like peptide 1 induces natriuresis in healthy subjects and in insulin-resistant obese men.
    The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:6

    Topics: Adult; Blood Glucose; Cross-Over Studies; Double-Blind Method; Drinking; Glomerular Filtration Rate; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin; Insulin Resistance; Kidney Tubules, Proximal; Male; Natriuresis; Obesity; Peptide Fragments; Protein Precursors; Protons; Renin; Renin-Angiotensin System; Sodium; Thirst; Urine

2004
Evaluation of the virological and metabolic effects of switching protease inhibitor combination antiretroviral therapy to nevirapine-based therapy for the treatment of HIV infection.
    AIDS research and human retroviruses, 2004, Volume: 20, Issue:6

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Blood Glucose; Body Composition; Bone Density; C-Peptide; Cyclopropanes; Drug Therapy, Combination; Female; Glucagon; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Insulin; Insulin Resistance; Lipids; Lipoproteins; Male; Nevirapine; Oxazines; Pilot Projects; RNA, Viral; Viral Load

2004
Effect of intravenous infusion of exenatide (synthetic exendin-4) on glucose-dependent insulin secretion and counterregulation during hypoglycemia.
    Diabetes, 2004, Volume: 53, Issue:9

    Topics: Adult; Blood Glucose; C-Peptide; Cross-Over Studies; Exenatide; Fatty Acids, Nonesterified; Glucagon; Humans; Hydrocortisone; Hypoglycemia; Infusions, Intravenous; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Peptides; Venoms

2004
Effect of growth hormone and 17beta-oestradiol treatment on metabolism and body composition in girls with Turner syndrome.
    Clinical endocrinology, 2005, Volume: 62, Issue:5

    Topics: Adolescent; Blood Glucose; Body Composition; Bone Density; Case-Control Studies; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Estradiol; Female; Glucagon; Glucose Tolerance Test; Growth Hormone; Humans; Insulin; Insulin Resistance; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Lipids; Turner Syndrome

2005
Contrasting insulin sensitivity of endogenous glucose production rate in subjects with hepatocyte nuclear factor-1beta and -1alpha mutations.
    Diabetes, 2006, Volume: 55, Issue:2

    Topics: Adult; Dose-Response Relationship, Drug; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glucose Clamp Technique; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Insulin; Insulin Resistance; Male; Mutation

2006
Metabolic effects of parenteral nutrition enriched with n-3 polyunsaturated fatty acids in critically ill patients.
    Clinical nutrition (Edinburgh, Scotland), 2006, Volume: 25, Issue:4

    Topics: Adult; Aged; Blood Glucose; Critical Care; Critical Illness; Energy Metabolism; Fat Emulsions, Intravenous; Fatty Acids, Omega-3; Female; Food, Fortified; Glucagon; Gluconeogenesis; Humans; Hydrocortisone; Insulin Resistance; Intensive Care Units; Lipid Metabolism; Liver; Male; Middle Aged; Parenteral Nutrition, Total

2006
Effect of pioglitazone on the metabolic and hormonal response to a mixed meal in type II diabetes.
    Clinical pharmacology and therapeutics, 2007, Volume: 81, Issue:2

    Topics: Adiponectin; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Administration Schedule; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Gluconeogenesis; Glucose Tolerance Test; Glycated Hemoglobin; Glycolysis; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Lactates; Male; Middle Aged; Pioglitazone; Thiazolidinediones

2007
Insulin counter-regulatory factors, fibrinogen and C-reactive protein during olanzapine administration: effects of the antidiabetic metformin.
    International clinical psychopharmacology, 2007, Volume: 22, Issue:2

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Blood Glucose; C-Reactive Protein; Double-Blind Method; Female; Fibrinogen; Glucagon; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Male; Metabolic Syndrome; Metformin; Middle Aged; Olanzapine; Schizophrenia; Sex Factors; Treatment Outcome; Tumor Necrosis Factor-alpha

2007
Effects of a 3-day fast on regional lipid and glucose metabolism in human skeletal muscle and adipose tissue.
    Acta physiologica (Oxford, England), 2007, Volume: 191, Issue:3

    Topics: Adipose Tissue; Adult; Arm; Calorimetry, Indirect; Fasting; Fatty Acids, Nonesterified; Glucagon; Glucose; Glycerol; Growth Hormone; Humans; Hydrocortisone; Hypoglycemic Agents; Insulin; Insulin Resistance; Isotope Labeling; Leg; Lipid Metabolism; Lipolysis; Male; Microdialysis; Muscle, Skeletal; Palmitates; Subcutaneous Fat; Subcutaneous Fat, Abdominal; Weight Loss

2007
Weight loss therapy improves pancreatic endocrine function in obese older adults.
    Obesity (Silver Spring, Md.), 2008, Volume: 16, Issue:6

    Topics: Aged; Aging; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Diet, Reducing; Exercise; Female; Glucagon; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Islets of Langerhans; Male; Obesity; Risk Factors; Weight Loss

2008
[The somatostatin infusion test for the evaluation of glucose utilization in bezafibrate medication].
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:9

    Topics: Adult; Bezafibrate; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Glucagon; Humans; Insulin; Insulin Resistance; Somatostatin; Time Factors

1984
Alcohol-potentiated reactive hypoglycaemia depends on the nature of the carbohydrate ingested at the same time.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1984, Volume: 19, Issue:1

    Topics: Adult; Alcohol Drinking; Alcoholic Beverages; Blood Glucose; Dietary Carbohydrates; Drug Synergism; Ethanol; Glucagon; Humans; Hypoglycemia; Insulin; Insulin Resistance; Male; Middle Aged; Obesity; Social Behavior; Starch; Sucrose

1984
Effects of potassium supplementation on insulin binding and insulin action in human obesity: protein-modified fast and refeeding.
    European journal of clinical investigation, 1984, Volume: 14, Issue:6

    Topics: Adult; Blood Glucose; Combined Modality Therapy; Dietary Proteins; Fasting; Female; Glucagon; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Monocytes; Obesity; Potassium; Potassium Chloride; Receptor, Insulin

1984
Glycemic response to stress is altered in euglycemic Pima Indians.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1994, Volume: 18, Issue:11

    Topics: Adolescent; Adult; Blood Glucose; Catecholamines; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Tolerance Test; Humans; Hydrocortisone; Indians, North American; Insulin; Insulin Resistance; Male; Mathematics; Obesity; Prevalence; Radioimmunoassay; Risk Factors; Software; Stress, Psychological; White People

1994
Regulation of glucose homeostasis in humans with denervated livers.
    The Journal of clinical investigation, 1997, Aug-15, Volume: 100, Issue:4

    Topics: Adult; Biomarkers; Blood Glucose; C-Peptide; Central Nervous System; Denervation; Glucagon; Glucose Clamp Technique; Growth Hormone; Homeostasis; Humans; Hydrocortisone; Hyperglycemia; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Resistance; Liver; Liver Transplantation; Middle Aged; Models, Biological; Somatostatin; Time Factors

1997
The effect of norepinephrine on insulin secretion and glucose effectiveness in non-insulin-dependent diabetes.
    Metabolism: clinical and experimental, 1997, Volume: 46, Issue:12

    Topics: Adult; Aged; Blood Glucose; C-Peptide; Catecholamines; Computer Simulation; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Male; Middle Aged; Models, Biological; Neurotransmitter Agents; Norepinephrine; Time Factors

1997
The effect of oral terbutaline on maternal glucose metabolism and energy expenditure in pregnancy.
    American journal of obstetrics and gynecology, 1998, Volume: 178, Issue:5

    Topics: Adrenergic beta-Agonists; Adult; Blood Glucose; Calorimetry, Indirect; Energy Metabolism; Female; Gestational Age; Glucagon; Glucose; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Lactic Acid; Liver; Pregnancy; Terbutaline; Tocolytic Agents

1998
Preoperative oral carbohydrate administration reduces postoperative insulin resistance.
    Clinical nutrition (Edinburgh, Scotland), 1998, Volume: 17, Issue:2

    Topics: Adolescent; Adult; Aged; Beverages; Blood Glucose; Carbohydrates; Fasting; Female; Glucagon; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Kinetics; Male; Middle Aged; Postoperative Complications; Preoperative Care

1998
Effect of hemipancreatectomy and of pancreatic diversion on the tolerance to a glucose load in humans.
    European journal of clinical investigation, 2000, Volume: 30, Issue:5

    Topics: Adult; Blood Glucose; C-Peptide; Fatty Acids, Nonesterified; Feedback; Female; Glucagon; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hydrocortisone; Hyperglycemia; Immunosuppression Therapy; Insulin; Insulin Resistance; Insulin Secretion; Male; Middle Aged; Pancreas Transplantation; Pancreatectomy

2000
A novel hyperglycaemic clamp for characterization of islet function in humans: assessment of three different secretagogues, maximal insulin response and reproducibility.
    European journal of clinical investigation, 2000, Volume: 30, Issue:5

    Topics: Adult; Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Clamp Technique; Humans; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Peptide Fragments; Protein Precursors; Reproducibility of Results

2000
Gluconeogenesis in moderately and severely hyperglycemic patients with type 2 diabetes mellitus.
    American journal of physiology. Endocrinology and metabolism, 2001, Volume: 280, Issue:1

    Topics: Aged; Blood Glucose; Deuterium; Diabetes Mellitus, Type 2; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Gluconeogenesis; Glucose; Glycolysis; Human Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Ketone Bodies; Male; Middle Aged; Tritium

2001
Physiologic modeling of the intravenous glucose tolerance test in type 2 diabetes: a new approach to the insulin compartment.
    Metabolism: clinical and experimental, 2001, Volume: 50, Issue:5

    Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Infusions, Intravenous; Insulin; Insulin Resistance; Kinetics; Male; Middle Aged; Models, Biological

2001
Systemic and regional free fatty acid metabolism in type 2 diabetes.
    American journal of physiology. Endocrinology and metabolism, 2001, Volume: 280, Issue:6

    Topics: Abdomen; Adipose Tissue; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glucagon; Hormones; Human Growth Hormone; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipolysis; Male; Middle Aged; Obesity; Palmitates; Protein Synthesis Inhibitors; Somatostatin; Tritium

2001
Impaired incretin response after a mixed meal is associated with insulin resistance in nondiabetic men.
    Diabetes care, 2001, Volume: 24, Issue:9

    Topics: Adult; Biomarkers; Blood Glucose; Blood Pressure; Body Weight; Eating; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Peptide Fragments; Postprandial Period; Protein Precursors; Regression Analysis

2001
Mechanism of amino acid-induced skeletal muscle insulin resistance in humans.
    Diabetes, 2002, Volume: 51, Issue:3

    Topics: Adenosine Diphosphate; Adult; Amino Acids; Blood Glucose; Deuterium; Epinephrine; Fasting; Glucagon; Glucose Clamp Technique; Glucose-6-Phosphate; Glycogen; Human Growth Hormone; Humans; Hydrocortisone; Hydrogen-Ion Concentration; Insulin; Insulin Resistance; Kinetics; Magnetic Resonance Spectroscopy; Male; Muscle, Skeletal; Phosphates; Phosphocreatine; Phosphorylation; Somatostatin

2002
Short-term treatment with metformin decreases serum leptin concentration without affecting body weight and body fat content in normal-weight healthy men.
    Metabolism: clinical and experimental, 2002, Volume: 51, Issue:4

    Topics: Adipose Tissue; Adult; Blood Pressure; Body Weight; C-Peptide; Diabetes Mellitus; Glucagon; Humans; Hydrocortisone; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Leptin; Male; Metformin; Obesity; Reference Values

2002
FFA cause hepatic insulin resistance by inhibiting insulin suppression of glycogenolysis.
    American journal of physiology. Endocrinology and metabolism, 2002, Volume: 283, Issue:1

    Topics: Adult; Blood Glucose; Fatty Acids, Nonesterified; Female; Glucagon; Gluconeogenesis; Glucose; Glucose Clamp Technique; Glycogen; Humans; Hydrocortisone; Infusions, Intravenous; Insulin; Insulin Resistance; Liver; Male; Reference Values; Somatostatin

2002
Danazol induces resistance to both insulin and glucagon in young women.
    Clinical science (London, England : 1979), 1992, Volume: 82, Issue:2

    Topics: Adult; Blood Glucose; C-Peptide; Cholesterol; Danazol; Endometriosis; Female; Glucagon; Humans; Insulin; Insulin Resistance; Models, Biological

1992
Daily magnesium supplements improve glucose handling in elderly subjects.
    The American journal of clinical nutrition, 1992, Volume: 55, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Blood Viscosity; Body Mass Index; C-Peptide; Double-Blind Method; Erythrocytes; Female; Glucagon; Homeostasis; Humans; Insulin; Insulin Resistance; Lactates; Magnesium; Male; Pyruvates

1992
Effect of recombinant human growth hormone on catabolic hormones and free fatty acids following thermal injury.
    The Journal of trauma, 1992, Volume: 32, Issue:6

    Topics: Burns; Catecholamines; Child; Double-Blind Method; Energy Metabolism; Fatty Acids, Nonesterified; Glucagon; Growth Hormone; Heart Rate; Humans; Hydrocortisone; Injections, Intramuscular; Injury Severity Score; Insulin; Insulin Resistance; Insulin-Like Growth Factor I; Respiration; Skin Transplantation; Wound Healing

1992
Dose-response relationships for the effects of insulin on glucose and fat metabolism in injured patients and control subjects.
    Clinical science (London, England : 1979), 1991, Volume: 80, Issue:1

    Topics: Adolescent; Adult; Basal Metabolism; Blood Flow Velocity; Blood Glucose; Dose-Response Relationship, Drug; Epinephrine; Female; Forearm; Fractures, Bone; Glucagon; Glucose Clamp Technique; Humans; Hydrocortisone; Insulin; Insulin Resistance; Lipid Metabolism; Male; Oxidation-Reduction

1991
Reduction of insulin resistance by combined kidney-pancreas transplantation in type 1 (insulin-dependent) diabetic patients.
    Diabetologia, 1990, Volume: 33, Issue:9

    Topics: Adult; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glycated Hemoglobin; Humans; Insulin; Insulin Infusion Systems; Insulin Resistance; Kidney Failure, Chronic; Kidney Transplantation; Male; Pancreas Transplantation; Reference Values

1990
Impairment of noninsulin-mediated glucose disposal in the elderly.
    The Journal of clinical endocrinology and metabolism, 1989, Volume: 68, Issue:3

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Animals; Blood Glucose; Fasting; Glucagon; Glucose; Humans; Hyperglycemia; Infusions, Intravenous; Insulin; Insulin Resistance; Middle Aged; Somatostatin

1989
[Comparison of biosynthetic human insulin and purified pork insulin. Studies in insulin-resistant obese patients using the insulin suppression test].
    Diabete & metabolisme, 1986, Volume: 12, Issue:1

    Topics: Adult; Aged; Animals; Blood Glucose; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose; Humans; Insulin; Insulin Resistance; Insulin, Regular, Pork; Male; Middle Aged; Obesity; Recombinant Proteins; Somatostatin; Swine

1986
Insulin resistance following nocturnal hypoglycaemia in insulin-dependent diabetes mellitus.
    Acta endocrinologica, 1987, Volume: 116, Issue:3

    Topics: Adult; Circadian Rhythm; Diabetes Mellitus, Type 1; Glucagon; Glucose Tolerance Test; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Insulin Resistance; Male; Somatostatin

1987
Insulin resistance in Graves' disease: a quantitative in-vivo evaluation.
    European journal of clinical investigation, 1988, Volume: 18, Issue:6

    Topics: Adult; Blood Glucose; C-Peptide; Female; Glucagon; Glucose; Graves Disease; Humans; Insulin; Insulin Resistance; Insulin Secretion; Liver; Male; Middle Aged

1988
Pharmacokinetics and metabolic effects of glibenclamide and glipizide in type 2 diabetics.
    European journal of clinical pharmacology, 1985, Volume: 28, Issue:6

    Topics: Aged; Blood Glucose; Body Weight; C-Peptide; Diabetes Mellitus, Type 2; Double-Blind Method; Erythrocytes; Female; Gastric Inhibitory Polypeptide; Glipizide; Glucagon; Glyburide; Glycosuria; Humans; Insulin; Insulin Resistance; Kinetics; Male; Middle Aged; Random Allocation; Sulfonylurea Compounds

1985
Insulin, free fatty acids, and glucose response to intravenous glucagon following myocardial infarction.
    Circulation, 1974, Volume: 49, Issue:2

    Topics: Acute Disease; Adult; Blood Glucose; Clinical Trials as Topic; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Tolerance Test; Humans; Injections, Intravenous; Insulin; Insulin Resistance; Insulin Secretion; Male; Middle Aged; Myocardial Infarction; Secretory Rate

1974

Other Studies

512 other study(ies) available for glucagon and Insulin Resistance

ArticleYear
Response to Letter to the Editor from Roy et al: "Impaired Suppression of Glucagon in Obese Subjects Parallels Decline in Insulin Sensitivity and Beta-Cell Function".
    The Journal of clinical endocrinology and metabolism, 2022, 02-17, Volume: 107, Issue:3

    Topics: Glucagon; Glucose Tolerance Test; Humans; Insulin Resistance; Obesity

2022
Letter to the Editor From Roy et al: "Impaired Suppression of Glucagon in Obese Subjects Parallels Decline in Insulin Sensitivity and Beta-cell Function".
    The Journal of clinical endocrinology and metabolism, 2022, 02-17, Volume: 107, Issue:3

    Topics: Glucagon; Glucose Tolerance Test; Humans; Insulin Resistance; Obesity

2022
Pancreatic and gut hormone responses to mixed meal test in post-chronic pancreatitis diabetes mellitus.
    Diabetes & metabolism, 2022, Volume: 48, Issue:3

    Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin; Insulin Resistance; Pancreatitis, Chronic; Peptide YY

2022
Timing of Meals and Exercise Affects Hormonal Control of Glucoregulation, Insulin Resistance, Substrate Metabolism, and Gastrointestinal Hormones, but Has Little Effect on Appetite in Postmenopausal Women.
    Nutrients, 2021, Dec-01, Volume: 13, Issue:12

    Topics: Aged; Aged, 80 and over; Appetite; Cholecystokinin; Eating; Exercise; Feeding Behavior; Female; Gastrointestinal Hormones; Ghrelin; Glucagon; Humans; Hunger; Insulin Resistance; Intestines; Middle Aged; Postmenopause; Satiation

2021
Pancreatic cancer-associated diabetes mellitus is characterized by reduced β-cell secretory capacity, rather than insulin resistance.
    Diabetes research and clinical practice, 2022, Volume: 185

    Topics: Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin; Insulin Resistance; Pancreatic Neoplasms

2022
Hyperglucagonemia in Pediatric Adiposity Associates With Cardiometabolic Risk Factors but Not Hyperglycemia.
    The Journal of clinical endocrinology and metabolism, 2022, 05-17, Volume: 107, Issue:6

    Topics: Adiposity; Adolescent; Blood Glucose; Body Mass Index; Cardiometabolic Risk Factors; Cardiovascular Diseases; Child; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Insulin Resistance; Overweight; Pediatric Obesity; Risk Factors; Young Adult

2022
The alpha-7 nicotinic acetylcholine receptor agonist GTS-21 engages the glucagon-like peptide-1 incretin hormone axis to lower levels of blood glucose in db/db mice.
    Diabetes, obesity & metabolism, 2022, Volume: 24, Issue:7

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzylidene Compounds; Blood Glucose; Diabetes Mellitus, Type 2; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose Tolerance Test; Humans; Incretins; Insulin; Insulin Resistance; Male; Mice; Mice, Knockout; Nicotinic Agonists; Pyridines; Sitagliptin Phosphate; Tyrosine

2022
A Study of Correlation of Glucagon-Insulin Ratio with Hba1c in Diabetic Patients in a Tertiary Care Hospital.
    The Journal of the Association of Physicians of India, 2022, Volume: 70, Issue:4

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucagon; Glycated Hemoglobin; Humans; Insulin; Insulin Resistance; Middle Aged; Prospective Studies; Tertiary Care Centers

2022
2'-O-Methylperlatolic Acid Enhances Insulin-Regulated Blood Glucose-Lowering Effect through Insulin Receptor Signaling Pathway.
    Journal of diabetes research, 2022, Volume: 2022

    Topics: Animals; Benzoates; Blood Glucose; Depsides; Diabetes Mellitus, Experimental; Glucagon; Glucose; Insulin; Insulin Resistance; Mice; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Salicylates; Signal Transduction; Streptozocin

2022
Incretin Response to Mixed Meal Challenge in Active Cushing's Disease and after Pasireotide Therapy.
    International journal of molecular sciences, 2022, May-06, Volume: 23, Issue:9

    Topics: Blood Glucose; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glycated Hemoglobin; Humans; Incretins; Insulin; Insulin Resistance; Meals; Pituitary ACTH Hypersecretion; Somatostatin

2022
Reduced insulin signaling and high glucagon in early insulin resistance impaired fast-fed regulation of renal gluconeogenesis via insulin receptor substrate.
    Journal of cellular biochemistry, 2022, Volume: 123, Issue:8

    Topics: Glucagon; Gluconeogenesis; Humans; Insulin; Insulin Resistance; Kidney; Liver; Phosphoenolpyruvate Carboxykinase (ATP); Receptor, Insulin; RNA, Messenger

2022
The rs10830963 Polymorphism of the MTNR1B Gene: Association With Abnormal Glucose, Insulin and C-peptide Kinetics.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose; Glucose Intolerance; Humans; Insulin; Insulin Resistance; Kinetics; Male; Prediabetic State; Receptor, Melatonin, MT2

2022
Endocrine-metabolic adaptations in Dorper ewes: comparison between single and twin pregnancies during gestation, parturition, and postpartum.
    Tropical animal health and production, 2022, Sep-16, Volume: 54, Issue:5

    Topics: Animals; Blood Glucose; Female; Glucagon; Hydrocortisone; Insulin; Insulin Resistance; Parturition; Postpartum Period; Pregnancy; Sheep; Sheep Diseases; Thyroid Hormones

2022
Determinants of hyperglucagonemia in pediatric non-alcoholic fatty liver disease.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adolescent; Child; Glucagon; Glucose; Glycated Hemoglobin; Humans; Insulin; Insulin Resistance; Non-alcoholic Fatty Liver Disease; Obesity; Triglycerides; Uric Acid

2022
The Different Insulin-Sensitising and Anti-Inflammatory Effects of Palmitoleic Acid and Oleic Acid in a Prediabetes Model.
    Journal of diabetes research, 2022, Volume: 2022

    Topics: Adiponectin; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Cytokines; Diabetes Mellitus, Type 2; Fatty Acids; Fatty Acids, Monounsaturated; Fatty Acids, Nonesterified; Glucagon; Glucose; Inflammation; Insulin; Insulin Resistance; Lipoprotein Lipase; Oleic Acid; Prediabetic State; Rats

2022
Lipid droplet accumulation in β cells in patients with type 2 diabetes is associated with insulin resistance, hyperglycemia and β cell dysfunction involving decreased insulin granules.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Blood Glucose; Boron Compounds; C-Peptide; Diabetes Mellitus, Type 2; Glucagon; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Hyperglycemia; Insulin; Insulin Resistance; Lipid Droplets

2022
Surfactin Mitigates a High-Fat Diet and Streptozotocin-Induced Type 2 Diabetes through Improving Pancreatic Dysfunction and Inhibiting Inflammatory Response.
    International journal of molecular sciences, 2022, Sep-21, Volume: 23, Issue:19

    Topics: Animals; Blood Glucose; Claudin-1; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Glucagon; Glucose; Inflammation; Insulin Resistance; Mice; Occludin; Pancreas; Pancreatic Hormones; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Proto-Oncogene Proteins c-akt; Streptozocin

2022
Hepatic Sam68 Regulates Systemic Glucose Homeostasis and Insulin Sensitivity.
    International journal of molecular sciences, 2022, Sep-29, Volume: 23, Issue:19

    Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Cycle Proteins; Cyclic AMP Response Element-Binding Protein; Diabetes Mellitus, Type 2; Gene Expression; Glucagon; Gluconeogenesis; Glucose; Hepatocytes; Homeostasis; Hyperglycemia; Insulin; Insulin Resistance; Liver; Mice; RNA-Binding Proteins; src-Family Kinases; Transcription Factors

2022
Predictors of acarbose therapeutic efficacy in newly diagnosed type 2 diabetes mellitus patients in China.
    BMC pharmacology & toxicology, 2022, 10-18, Volume: 23, Issue:1

    Topics: Acarbose; Blood Glucose; China; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glycated Hemoglobin; Humans; Insulin; Insulin Resistance; Insulins

2022
Chronic physiologic hyperglycemia impairs insulin-mediated suppression of plasma glucagon concentration in healthy humans.
    Metabolism: clinical and experimental, 2023, Volume: 142

    Topics: Blood Glucose; Diabetes Mellitus, Type 2; Glucagon; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Insulin Resistance

2023
Hypoglycemia in children and young adults with cystic fibrosis during oral glucose tolerance testing vs. continuous glucose monitoring.
    Pediatric pulmonology, 2023, Volume: 58, Issue:9

    Topics: Adolescent; Blood Glucose; Blood Glucose Self-Monitoring; Child; Cystic Fibrosis; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Insulin Resistance; Young Adult

2023
Blocking IL-6 signaling improves glucose tolerance via SLC39A5-mediated suppression of glucagon secretion.
    Metabolism: clinical and experimental, 2023, Volume: 146

    Topics: Animals; Blood Glucose; Cation Transport Proteins; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Secreting Cells; Glucose; Humans; Inflammation; Insulin; Insulin Resistance; Interleukin-6; Macaca mulatta; Mice; Obesity

2023
Lower serum zinc level is associated with higher fasting insulin in type 2 diabetes mellitus (T2DM) and relates with disturbed glucagon suppression response in male patients.
    Primary care diabetes, 2023, Volume: 17, Issue:5

    Topics: Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Glycated Hemoglobin; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Male

2023
Adipose tissue-derived FABP4 mediates glucagon-stimulated hepatic glucose production in gestational diabetes.
    Diabetes, obesity & metabolism, 2023, Volume: 25, Issue:11

    Topics: Adipokines; Adipose Tissue; Animals; Diabetes, Gestational; Fatty Acid-Binding Proteins; Female; Glucagon; Glucose; Humans; Infant, Newborn; Insulin Resistance; Liver; Mice; Pregnancy

2023
Hepatic sialic acid synthesis modulates glucose homeostasis in both liver and skeletal muscle.
    Molecular metabolism, 2023, Volume: 78

    Topics: Animals; Glucagon; Glucose; Homeostasis; Insulin; Insulin Resistance; Liver; Mice; Muscle, Skeletal; N-Acetylneuraminic Acid; Polysaccharides

2023
PAHSAs enhance hepatic and systemic insulin sensitivity through direct and indirect mechanisms.
    The Journal of clinical investigation, 2019, 10-01, Volume: 129, Issue:10

    Topics: Adipose Tissue, White; Animals; Cyclic AMP; Diet, High-Fat; Glucagon; In Vitro Techniques; Insulin Resistance; Lipolysis; Liver; Male; Mice; Mice, Inbred C57BL; Models, Biological; Receptors, G-Protein-Coupled; Signal Transduction; Stearates

2019
Obesity dysregulates fasting-induced changes in glucagon secretion.
    The Journal of endocrinology, 2019, Volume: 243, Issue:2

    Topics: Adult; Animals; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Humans; Hyperglycemia; Insulin; Insulin Resistance; Male; Mice, Inbred C57BL; Middle Aged; Obesity; Pancreas

2019
Impaired glucagon suppression and reduced insulin sensitivity in subjects with prediabetes undergoing atorvastatin therapy.
    European journal of endocrinology, 2019, Volume: 181, Issue:6

    Topics: Adult; Aged; Atorvastatin; Blood Glucose; Blotting, Western; Cell Line; Female; Glucagon; Glucose Tolerance Test; Humans; Immunoprecipitation; Insulin Resistance; Male; Middle Aged; Multivariate Analysis; Prediabetic State

2019
Antidiabetic effects and sustained metabolic benefits of sub-chronic co-administration of exendin-4/gastrin and xenin-8-Gln in high fat fed mice.
    European journal of pharmacology, 2019, Dec-15, Volume: 865

    Topics: Animals; Body Weight; Diet, High-Fat; Drug Interactions; Energy Metabolism; Exenatide; Gastrins; Glucagon; Glycated Hemoglobin; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Metabolism; Mice; Pancreas; Peptide Fragments; Time Factors

2019
The glutamate receptor GluK2 contributes to the regulation of glucose homeostasis and its deterioration during aging.
    Molecular metabolism, 2019, Volume: 30

    Topics: Animals; Blood Glucose; Female; Glucagon; Glucagon-Secreting Cells; Glucose; GluK2 Kainate Receptor; Homeostasis; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Glucagon; Receptors, Kainic Acid

2019
Modelling the effects of glucagon during glucose tolerance testing.
    Theoretical biology & medical modelling, 2019, 12-12, Volume: 16, Issue:1

    Topics: Blood Glucose; Computer Simulation; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin Resistance; Linear Models; Models, Biological; Reproducibility of Results

2019
Childhood trauma and glucose metabolism in patients with first-episode psychosis.
    Psychoneuroendocrinology, 2020, Volume: 113

    Topics: Adult; Adverse Childhood Experiences; Antipsychotic Agents; Biomarkers; C-Peptide; Female; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Glucose; Humans; Insulin; Insulin Resistance; Leptin; Male; Middle Aged; Nicotinamide Phosphoribosyltransferase; Plasminogen Activator Inhibitor 1; Psychotic Disorders; Resistin

2020
Incretin hormones, insulin, glucagon and advanced glycation end products in relation to cognitive function in older people with and without diabetes, a population-based study.
    Diabetic medicine : a journal of the British Diabetic Association, 2020, Volume: 37, Issue:7

    Topics: Aged; Blood Glucose; Case-Control Studies; Cognition; Cross-Sectional Studies; Diabetes Mellitus; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Glycation End Products, Advanced; Humans; Insulin; Insulin Resistance; Male; Mental Status and Dementia Tests; Optical Imaging; Sweden

2020
Stress adaptation is associated with insulin resistance in women with gestational diabetes mellitus.
    Nutrition & diabetes, 2020, 01-22, Volume: 10, Issue:1

    Topics: Adult; Blood Glucose; Diabetes, Gestational; Epinephrine; Female; Glucagon; Glutathione; Hormones; Humans; Hydrocortisone; Insulin Resistance; Malondialdehyde; Norepinephrine; Oxidative Stress; Pregnancy; Stress, Physiological; Stress, Psychological; Superoxide Dismutase

2020
Glucagon from the phylogenetically ancient paddlefish provides a template for the design of a long-acting peptide with effective anti-diabetic and anti-obesity activities.
    European journal of pharmacology, 2020, Jul-05, Volume: 878

    Topics: Amino Acid Sequence; Animals; Anti-Obesity Agents; Apoptosis; Blood Glucose; Body Weight; Cell Proliferation; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose Transporter Type 2; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Secreting Cells; Islets of Langerhans; Male; Mice; Neoplasm Proteins; Obesity; Receptors, Glucagon; Structure-Activity Relationship

2020
Dapagliflozin exerts positive effects on beta cells, decreases glucagon and does not alter beta- to alpha-cell transdifferentiation in mouse models of diabetes and insulin resistance.
    Biochemical pharmacology, 2020, Volume: 177

    Topics: Animals; Benzhydryl Compounds; Blood Glucose; Body Weight; Cell Transdifferentiation; Diabetes Mellitus, Experimental; Diet, High-Fat; Energy Intake; Glucagon; Glucagon-Secreting Cells; Glucosides; Homeodomain Proteins; Hydrocortisone; Insulin; Insulin Resistance; Insulin-Secreting Cells; Islets of Langerhans; Male; Mice, Transgenic; Sodium-Glucose Transporter 2 Inhibitors; Streptozocin; Trans-Activators

2020
Plasma glucagon levels measured by sandwich ELISA are correlated with impaired glucose tolerance in type 2 diabetes.
    Endocrine journal, 2020, Sep-28, Volume: 67, Issue:9

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Female; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Male; Middle Aged

2020
Inhibition of prolyl hydroxylases increases hepatic insulin and decreases glucagon sensitivity by an HIF-2α-dependent mechanism.
    Molecular metabolism, 2020, Volume: 41

    Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Glucagon; Glucose; Hepatocytes; Humans; Insulin; Insulin Resistance; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Prolyl Hydroxylases; Prolyl-Hydroxylase Inhibitors; Signal Transduction

2020
The effect of the ghrelin-receptor agonist capromorelin on glucose metabolism in healthy cats.
    Domestic animal endocrinology, 2021, Volume: 74

    Topics: Animals; Blood Glucose; Cats; Glucagon; Glucose; Glucose Tolerance Test; Insulin; Insulin Resistance; Male; Piperidines; Pyrazoles; Receptors, Ghrelin

2021
Fasting serum total bile acid levels are associated with insulin sensitivity, islet β-cell function and glucagon levels in response to glucose challenge in patients with type 2 diabetes.
    Endocrine journal, 2020, Nov-28, Volume: 67, Issue:11

    Topics: Adult; Bile Acids and Salts; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Middle Aged

2020
Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis.
    Molecular metabolism, 2020, Volume: 42

    Topics: Adult; Amino Acids; Animals; Blood Glucose; Fatty Liver; Female; Glucagon; Glucagon-Secreting Cells; Glucose; Hepatocytes; Humans; Insulin; Insulin Resistance; Liver; Male; Mice; Mice, Inbred C57BL; Middle Aged; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; Receptors, Glucagon; Urea

2020
Direct Effects of D-Chiro-Inositol on Insulin Signaling and Glucagon Secretion of Pancreatic Alpha Cells.
    Biomolecules, 2020, 10-04, Volume: 10, Issue:10

    Topics: Animals; Cell Line, Tumor; Glucagon; Glucagon-Secreting Cells; Inositol; Insulin; Insulin Resistance; Mice; Palmitic Acid; Signal Transduction

2020
The liver-alpha cell axis associates with liver fat and insulin resistance: a validation study in women with non-steatotic liver fat levels.
    Diabetologia, 2021, Volume: 64, Issue:3

    Topics: Adiposity; Adult; Alanine; Biomarkers; Blood Chemical Analysis; Cross-Sectional Studies; Female; Glucagon; Glucagon-Secreting Cells; Humans; Insulin Resistance; Liver; Magnetic Resonance Imaging; Non-alcoholic Fatty Liver Disease; Predictive Value of Tests; Prognosis; Prospective Studies

2021
Development and characterisation of novel, enzymatically stable oxytocin analogues with beneficial antidiabetic effects in high fat fed mice.
    Biochimica et biophysica acta. General subjects, 2021, Volume: 1865, Issue:3

    Topics: Animals; Blood Glucose; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Energy Intake; Female; Glucagon; Half-Life; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Mice; Obesity; Oligopeptides; Oxytocin; Protein Stability; Triglycerides

2021
Impaired Suppression of Glucagon in Obese Subjects Parallels Decline in Insulin Sensitivity and Beta-Cell Function.
    The Journal of clinical endocrinology and metabolism, 2021, 04-23, Volume: 106, Issue:5

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Glucose Clamp Technique; Glucose Intolerance; Glucose Tolerance Test; Hispanic or Latino; Humans; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Middle Aged; Obesity; Prediabetic State; United States; Veterans

2021
The effects of an alpha-2-adrenoceptor agonist, antagonist, and their combination on the blood insulin, glucose, and glucagon concentrations in insulin sensitive and dysregulated horses.
    Veterinary journal (London, England : 1997), 2021, Volume: 269

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Blood Glucose; Drug Interactions; Female; Glucagon; Horses; Hypnotics and Sedatives; Imidazoles; Insulin; Insulin Resistance; Male; Quinolizines

2021
Low-Density Lipoprotein Cholesterol Is Associated With Insulin Secretion.
    The Journal of clinical endocrinology and metabolism, 2021, 05-13, Volume: 106, Issue:6

    Topics: Adult; Blood Glucose; Cholesterol, LDL; Cohort Studies; Diabetes Mellitus, Type 2; Fasting; Female; Germany; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Pancreas

2021
Bihormonal dysregulation of insulin and glucagon contributes to glucose intolerance development at one year post-delivery in women with gestational diabetes: a prospective cohort study using an early postpartum 75-g glucose tolerance test.
    Endocrine journal, 2021, Aug-28, Volume: 68, Issue:8

    Topics: Adult; Blood Glucose; Body Mass Index; Diabetes, Gestational; Fasting; Female; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Pregnancy; Prospective Studies

2021
Mathematical Model of Glucagon Kinetics for the Assessment of Insulin-Mediated Glucagon Inhibition During an Oral Glucose Tolerance Test.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Blood Glucose; Glucagon; Glucagon-Secreting Cells; Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Kinetics; Models, Theoretical

2021
Metabolic effects of 1-week binge drinking and fast food intake during Roskilde Festival in young healthy male adults.
    European journal of endocrinology, 2021, May-21, Volume: 185, Issue:1

    Topics: Adult; Aspartate Aminotransferases; Binge Drinking; Blood Glucose; C-Peptide; C-Reactive Protein; Denmark; Diet; Elasticity Imaging Techniques; Fast Foods; Fatty Liver; Fibroblast Growth Factors; Glucagon; Glucose Tolerance Test; Growth Differentiation Factor 15; Holidays; Humans; Insulin Resistance; Liver; Male; Young Adult

2021
Lack of Improvement in Insulin Sensitivity After Pancreas Transplantation in Recipients With a High Level of Calcineurin Inhibitors.
    Pancreas, 2021, 04-01, Volume: 50, Issue:4

    Topics: Adult; Blood Glucose; Calcineurin Inhibitors; Cyclosporine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Kaplan-Meier Estimate; Male; Middle Aged; Pancreas Transplantation; Tacrolimus

2021
Acute pancreatitis-induced islet dysfunction in ferrets.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2021, Volume: 21, Issue:5

    Topics: Acute Disease; Amylases; Animals; Blood Glucose; Ceruletide; Ferrets; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Insulin; Insulin Resistance; Interleukin-6; Lipase; Pancreatitis; Tumor Necrosis Factor-alpha

2021
Sam68 promotes hepatic gluconeogenesis via CRTC2.
    Nature communications, 2021, 06-07, Volume: 12, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Animals; Blood Glucose; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Gene Expression Regulation; Glucagon; Gluconeogenesis; Glucose; Hepatocytes; Homeostasis; Humans; Hyperglycemia; Insulin Resistance; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; RNA-Binding Proteins; Transcription Factors; Up-Regulation

2021
Activation of PI3K/Akt Signaling Pathway in Rat Hypothalamus Induced by an Acute Oral Administration of D-Pinitol.
    Nutrients, 2021, Jun-30, Volume: 13, Issue:7

    Topics: Administration, Oral; Animals; Blood Glucose; Enzyme Activation; Glucagon; Homeostasis; Hypothalamus; Inositol; Insulin; Insulin Resistance; Insulin-Like Growth Factor I; Male; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats, Wistar; Signal Transduction

2021
O-GlcNAcylated p53 in the liver modulates hepatic glucose production.
    Nature communications, 2021, 08-20, Volume: 12, Issue:1

    Topics: Acetylglucosamine; Animals; Base Sequence; Caloric Restriction; Cell Line; Colforsin; Diabetes Mellitus, Type 2; Epinephrine; Glucagon; Glucocorticoids; Gluconeogenesis; Glucose; Glycosylation; Hepatocytes; Humans; Hydrocortisone; Hyperglycemia; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Liver; Mice, Inbred C57BL; Mice, Knockout; Obesity; Phosphoenolpyruvate Carboxykinase (GTP); Promoter Regions, Genetic; Protein Binding; Protein Stability; Pyruvic Acid; RNA, Messenger; Transcription, Genetic; Tumor Suppressor Protein p53

2021
Increased Insulin Resistance and Glucagon Levels in Mild/Inactive Systemic Lupus Erythematosus Patients Despite Normal Glucose Tolerance.
    Arthritis care & research, 2018, Volume: 70, Issue:1

    Topics: Adult; Biomarkers; Blood Glucose; Case-Control Studies; Cross-Sectional Studies; Fasting; Female; Glucagon; Glucose Tolerance Test; Glucose Transporter Type 4; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Lupus Erythematosus, Systemic; Muscle, Skeletal; Postprandial Period; Severity of Illness Index

2018
Tributyltin in male mice disrupts glucose homeostasis as well as recovery after exposure: mechanism analysis.
    Archives of toxicology, 2017, Volume: 91, Issue:10

    Topics: Administration, Oral; Animals; Blood Glucose; Body Weight; Glucagon; Glucose; Homeostasis; Hormones; Insulin; Insulin Resistance; Liver; Male; Mice; Muscle, Skeletal; Signal Transduction; Trialkyltin Compounds

2017
Curcumin reverses the depressive-like behavior and insulin resistance induced by chronic mild stress.
    Metabolic brain disease, 2017, Volume: 32, Issue:4

    Topics: Animals; Behavior, Animal; Blood Glucose; Corticosterone; Curcumin; Depression; Disease Models, Animal; Glucagon; Glucose Tolerance Test; Insulin; Insulin Resistance; Leptin; Male; Pioglitazone; Rats; Rats, Sprague-Dawley; Stress, Psychological; Thiazolidinediones

2017
How Should We Think About the Role of the Brain in Glucose Homeostasis and Diabetes?
    Diabetes, 2017, Volume: 66, Issue:7

    Topics: Blood Glucose; Brain; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glucagon; Glucose; Homeostasis; Humans; Insulin Resistance; Insulin-Secreting Cells; Islets of Langerhans

2017
Short-Term Moderate Sleep Restriction Decreases Insulin Sensitivity in Young Healthy Adults.
    Sleep health, 2016, Volume: 2, Issue:1

    Topics: Adolescent; Adult; Blood Glucose; Fasting; Female; Glucagon; Glucose Tolerance Test; Humans; Hydrocortisone; Insulin; Insulin Resistance; Male; Sleep Deprivation; Young Adult

2016
Higher glucagon-to-insulin ratio is associated with elevated glycated hemoglobin levels in type 2 diabetes patients.
    The Korean journal of internal medicine, 2019, Volume: 34, Issue:5

    Topics: Adult; Aged; Biomarkers; Body Mass Index; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Glycated Hemoglobin; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Postprandial Period

2019
Hyperglucagonemia correlates with plasma levels of non-branched-chain amino acids in patients with liver disease independent of type 2 diabetes.
    American journal of physiology. Gastrointestinal and liver physiology, 2018, 01-01, Volume: 314, Issue:1

    Topics: Adult; Aged; Amino Acids; Biomarkers; Body Mass Index; Case-Control Studies; Cholesterol; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Glucagon-Secreting Cells; Glycated Hemoglobin; Humans; Insulin Resistance; Liver; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Up-Regulation

2018
Acute activation of GLP-1-expressing neurons promotes glucose homeostasis and insulin sensitivity.
    Molecular metabolism, 2017, Volume: 6, Issue:11

    Topics: Animals; Blood Glucose; Energy Metabolism; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose; Glucose Tolerance Test; Homeostasis; Insulin; Insulin Resistance; Mice; Mice, Transgenic; Neurons; Proglucagon; Receptors, Glucagon

2017
Differential associations of lower cardiac vagal tone with insulin resistance and insulin secretion in recently diagnosed type 1 and type 2 diabetes.
    Metabolism: clinical and experimental, 2018, Volume: 79

    Topics: Adolescent; Adult; Aged; C-Peptide; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Clamp Technique; Heart; Heart Rate; Humans; Insulin; Insulin Resistance; Lipids; Male; Middle Aged; Vagus Nerve; Young Adult

2018
Impaired Insulin Action Is Associated With Increased Glucagon Concentrations in Nondiabetic Humans.
    The Journal of clinical endocrinology and metabolism, 2018, 01-01, Volume: 103, Issue:1

    Topics: Biomarkers; Blood Glucose; C-Peptide; Cross-Sectional Studies; Female; Follow-Up Studies; Glucagon; Glucagon-Secreting Cells; Glucose Tolerance Test; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Middle Aged; Prediabetic State; Prognosis

2018
Honokiol protects pancreatic β cell against high glucose and intermittent hypoxia-induced injury by activating Nrf2/ARE pathway in vitro and in vivo.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 97

    Topics: Animals; Apoptosis; Biphenyl Compounds; Blood Glucose; Cell Proliferation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Free Radical Scavengers; Glucagon; Hypoxia; Insulin; Insulin Resistance; Insulin-Secreting Cells; Lignans; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sleep Apnea, Obstructive

2018
The influence of adiposity and acute exercise on circulating hepatokines in normal-weight and overweight/obese men.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2018, Volume: 43, Issue:5

    Topics: Adiposity; Adult; alpha-2-HS-Glycoprotein; Biomarkers; Blood Glucose; Body Composition; Body Mass Index; Body Weight; Case-Control Studies; Exercise; Exercise Test; Fibroblast Growth Factors; Follistatin; Glucagon; Humans; Insulin; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Life Style; Male; Middle Aged; Obesity; Overweight; Selenoprotein P; Young Adult

2018
Evidence of a liver-alpha cell axis in humans: hepatic insulin resistance attenuates relationship between fasting plasma glucagon and glucagonotropic amino acids.
    Diabetologia, 2018, Volume: 61, Issue:3

    Topics: Aged; Alanine; Amino Acids; Cross-Sectional Studies; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin Resistance; Liver; Magnetic Resonance Spectroscopy; Male; Middle Aged

2018
Lipidized prolactin-releasing peptide improved glucose tolerance in metabolic syndrome: Koletsky and spontaneously hypertensive rat study.
    Nutrition & diabetes, 2018, 01-16, Volume: 8, Issue:1

    Topics: Adipose Tissue; Animals; Blood Glucose; Blood Pressure; Body Weight; Brain; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Hypertension; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Lipids; Male; Metabolic Syndrome; Obesity; Prolactin-Releasing Hormone; Rats, Inbred SHR

2018
Immunohistochemical expression of insulin, glucagon, and somatostatin in pancreatic islets of horses with and without insulin resistance.
    American journal of veterinary research, 2018, Volume: 79, Issue:2

    Topics: Animals; Female; Glucagon; Horse Diseases; Horses; Immunohistochemistry; Insulin; Insulin Resistance; Islets of Langerhans; Male; Somatostatin

2018
5-aminolevulinic acid (ALA) deficiency causes impaired glucose tolerance and insulin resistance coincident with an attenuation of mitochondrial function in aged mice.
    PloS one, 2018, Volume: 13, Issue:1

    Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Blood Glucose; Glucagon; Gluconeogenesis; Glucose Intolerance; Insulin; Insulin Resistance; Levulinic Acids; Mice; Mice, Transgenic; Mitochondria; Signal Transduction

2018
Roux-en-Y gastric bypass compared with equivalent diet restriction: Mechanistic insights into diabetes remission.
    Diabetes, obesity & metabolism, 2018, Volume: 20, Issue:7

    Topics: Blood Glucose; Caloric Restriction; Diabetes Mellitus, Type 2; Fasting; Female; Gastric Bypass; Gastric Inhibitory Polypeptide; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Liver; Male; Middle Aged; Obesity; Peptide YY; Postprandial Period; Remission Induction

2018
Glucagon-Like Peptide-1 Receptor Agonist and Glucagon Increase Glucose-Stimulated Insulin Secretion in Beta Cells via Distinct Adenylyl Cyclases.
    International journal of medical sciences, 2018, Volume: 15, Issue:6

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cell Line; Cyclic AMP; Diabetes Mellitus; Dideoxyadenosine; Diet, High-Fat; Exenatide; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucose; Humans; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Mice; Mice, Obese; Peptides; Venoms

2018
Dendrobium Officinale Kimura et Migo Ameliorates Insulin Resistance in Rats with Diabetic Nephropathy.
    Medical science monitor basic research, 2018, May-31, Volume: 24

    Topics: Animals; C-Reactive Protein; Cytokines; Dendrobium; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Glucagon; Insulin; Insulin Resistance; Interleukin-6; Rats; Rats, Sprague-Dawley; Toll-Like Receptors; Tumor Necrosis Factor-alpha

2018
p8 deficiency leads to elevated pancreatic beta cell mass but does not contribute to insulin resistance in mice fed with high-fat diet.
    PloS one, 2018, Volume: 13, Issue:7

    Topics: Animals; Diet, High-Fat; Dietary Fats; DNA-Binding Proteins; Energy Metabolism; Female; Glucagon; Glucose; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Mice, Inbred C57BL; Mice, Knockout; Neoplasm Proteins

2018
Contribution of systemic inflammation to permanence of K
    American journal of physiology. Endocrinology and metabolism, 2018, 12-01, Volume: 315, Issue:6

    Topics: Animals; Blood Glucose; Cytokines; Diabetes Mellitus; Glucagon; Glucagon-Like Peptide 1; Glyburide; Inflammation; Insulin; Insulin Resistance; Leptin; Mice; Mice, Transgenic; Mutation; Potassium Channels, Inwardly Rectifying

2018
Glucose intolerance in monosodium glutamate obesity is linked to hyperglucagonemia and insulin resistance in α cells.
    Journal of cellular physiology, 2019, Volume: 234, Issue:5

    Topics: Adipose Tissue, White; Animals; Biomarkers; Blood Glucose; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Glucagon; Glucagon-Secreting Cells; Glucose Intolerance; Insulin; Insulin Resistance; Liver; Male; Mice; Obesity; Phosphoenolpyruvate Carboxykinase (ATP); Phosphorylation; Sodium Glutamate; TOR Serine-Threonine Kinases

2019
Association of glucagon-to-insulin ratio and nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus.
    Diabetes & vascular disease research, 2019, Volume: 16, Issue:2

    Topics: Adiposity; Adult; Aged; Biomarkers; Body Mass Index; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Prevalence; Prognosis; Republic of Korea; Risk Assessment; Risk Factors; Time Factors; Ultrasonography

2019
Chronic Exposure to Palmitate Impairs Insulin Signaling in an Intestinal L-cell Line: A Possible Shift from GLP-1 to Glucagon Production.
    International journal of molecular sciences, 2018, Nov-28, Volume: 19, Issue:12

    Topics: Cell Line; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin Resistance; Palmitates; Proprotein Convertase 2; Signal Transduction

2018
PGC1A regulates the IRS1:IRS2 ratio during fasting to influence hepatic metabolism downstream of insulin.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 03-05, Volume: 116, Issue:10

    Topics: Animals; Cyclic AMP Response Element-Binding Protein; Diabetes Mellitus, Type 2; Fasting; Female; Gene Expression Regulation; Glucagon; Gluconeogenesis; Glucose; Hepatocytes; Homeostasis; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Liver; Liver Diseases; Male; Mice; Models, Animal; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Proto-Oncogene Proteins c-akt; Signal Transduction

2019
Mild Physiologic Hyperglycemia Induces Hepatic Insulin Resistance in Healthy Normal Glucose-Tolerant Participants.
    The Journal of clinical endocrinology and metabolism, 2019, 07-01, Volume: 104, Issue:7

    Topics: Adult; Blood Glucose; C-Peptide; Female; Glucagon; Gluconeogenesis; Glucose; Glucose Clamp Technique; Glycogenolysis; Healthy Volunteers; Humans; Hyperglycemia; Insulin; Insulin Resistance; Liver; Male; Middle Aged; Tritium

2019
Timing Modulates the Effect of Sleep Loss on Glucose Homeostasis.
    The Journal of clinical endocrinology and metabolism, 2019, 07-01, Volume: 104, Issue:7

    Topics: Adult; Blood Glucose; Cross-Over Studies; Glucagon; Glucagon-Secreting Cells; Glucose Clamp Technique; Healthy Volunteers; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Pituitary-Adrenal System; Random Allocation; Sleep Deprivation; Time Factors; Young Adult

2019
A novel measure of glucose homeostasis (or loss thereof) comprising the joint dynamics of glucose, insulin, glucagon, and cortisol.
    American journal of physiology. Endocrinology and metabolism, 2019, 06-01, Volume: 316, Issue:6

    Topics: Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 2; Glucagon; Homeostasis; Humans; Hydrocortisone; Insulin; Insulin Resistance; Insulin Secretion; Prediabetic State

2019
Glucose-dependent Insulinotropic Polypeptide (GIP) Resistance and β-cell Dysfunction Contribute to Hyperglycaemia in Acromegaly.
    Scientific reports, 2019, 04-04, Volume: 9, Issue:1

    Topics: Acromegaly; Adult; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Clamp Technique; Humans; Hyperglycemia; Incretins; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Prospective Studies; Receptors, Gastrointestinal Hormone

2019
Phosphorylation of Forkhead Protein FoxO1 at S253 Regulates Glucose Homeostasis in Mice.
    Endocrinology, 2019, 05-01, Volume: 160, Issue:5

    Topics: Alanine; Animals; Blood Glucose; Forkhead Box Protein O1; Glucagon; Glucose; Homeostasis; Insulin; Insulin Resistance; Islets of Langerhans; Liver; Mice, Inbred C57BL; Mice, Transgenic; Phosphorylation; Serine

2019
The short-chain fatty acid propionate increases glucagon and FABP4 production, impairing insulin action in mice and humans.
    Science translational medicine, 2019, 04-24, Volume: 11, Issue:489

    Topics: Animals; Fatty Acid-Binding Proteins; Female; Glucagon; Glycogen; Humans; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Propionates; Weight Gain

2019
Proinsulin associates with poor β-cell function, glucose-dependent insulinotropic peptide, and insulin resistance in persistent type 2 diabetes after Roux-en-Y gastric bypass in humans.
    Journal of diabetes, 2020, Volume: 12, Issue:1

    Topics: Adult; Blood Glucose; Body Weight; C-Peptide; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Gastric Bypass; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Middle Aged; Recurrence

2020
Biomarkers of insulin action during single soccer sessions before and after a 12-week training period in type 2 diabetes patients on a caloric-restricted diet.
    Physiology & behavior, 2019, 10-01, Volume: 209

    Topics: Aged; Biomarkers; Blood Glucose; Body Composition; Diabetes Mellitus, Type 2; Diet, Reducing; Exercise Therapy; Female; Glucagon; Humans; Insulin; Insulin Resistance; Lactic Acid; Leptin; Male; Middle Aged; Physical Conditioning, Human; Soccer; Treatment Outcome

2019
Beta and alpha cell function in metabolically healthy but obese subjects: relationship with entero-insular axis.
    Obesity (Silver Spring, Md.), 2013, Volume: 21, Issue:2

    Topics: Adult; Area Under Curve; Blood Glucose; C-Peptide; Fasting; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Obesity

2013
Reduced postprandial GLP-1 responses in women with gestational diabetes mellitus.
    Diabetes, obesity & metabolism, 2013, Volume: 15, Issue:8

    Topics: Adult; Area Under Curve; Biomarkers; Blood Glucose; Body Mass Index; C-Peptide; Diabetes, Gestational; Female; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Glycated Hemoglobin; Homeostasis; Humans; Insulin; Insulin Resistance; Insulin Secretion; Postpartum Period; Postprandial Period; Pregnancy

2013
X-box binding protein 1 is essential for insulin regulation of pancreatic α-cell function.
    Diabetes, 2013, Volume: 62, Issue:7

    Topics: Animals; DNA-Binding Proteins; Glucagon; Glucagon-Secreting Cells; Glucose Intolerance; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Knockout; Phosphorylation; Proto-Oncogene Proteins c-akt; Regulatory Factor X Transcription Factors; Signal Transduction; Transcription Factors; X-Box Binding Protein 1

2013
Glucose homeostasis, obesity and diabetes.
    Best practice & research. Clinical obstetrics & gynaecology, 2013, Volume: 27, Issue:5

    Topics: Aging; Body Mass Index; Diabetes Mellitus, Type 2; Glucagon; Glucose; Glucose Intolerance; Glucose Transport Proteins, Facilitative; Glycogen; Homeostasis; Humans; Inflammation Mediators; Insulin; Insulin Resistance; Metabolic Syndrome; Obesity; Obesity, Abdominal; Sodium-Glucose Transport Proteins

2013
Postnatal development of the endocrine pancreas in mice lacking functional GABAB receptors.
    American journal of physiology. Endocrinology and metabolism, 2013, May-15, Volume: 304, Issue:10

    Topics: Animals; Animals, Newborn; Body Weight; Female; Gene Expression Regulation; Glucagon; Glutamate Decarboxylase; Insulin; Insulin Resistance; Islets of Langerhans; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Organ Size; Proliferating Cell Nuclear Antigen; Real-Time Polymerase Chain Reaction; Receptors, GABA-B; RNA

2013
Circulating glucagon to ghrelin ratio as a determinant of insulin resistance in hyperthyroidism.
    Endocrine, 2014, Volume: 45, Issue:1

    Topics: Adipose Tissue; Adult; Aged; Body Composition; Fasting; Female; Ghrelin; Glucagon; Graves Disease; Humans; Hyperthyroidism; Insulin Resistance; Male; Middle Aged

2014
GLP-1 and the long-term outcome of type 2 diabetes mellitus after Roux-en-Y gastric bypass surgery in morbidly obese subjects.
    Annals of surgery, 2013, Volume: 257, Issue:5

    Topics: Absorptiometry, Photon; Aged; Biomarkers; Blood Glucose; Body Composition; C-Peptide; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Gastric Bypass; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Obesity, Morbid; Treatment Outcome

2013
Exaggerated glucagon-like peptide 1 response is important for improved β-cell function and glucose tolerance after Roux-en-Y gastric bypass in patients with type 2 diabetes.
    Diabetes, 2013, Volume: 62, Issue:9

    Topics: Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Female; Gastric Bypass; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Humans; Insulin Resistance; Insulin-Secreting Cells; Male; Middle Aged; Peptide Fragments; Receptors, Glucagon

2013
Impairment of pancreatic β-cell function by chronic intermittent hypoxia.
    Experimental physiology, 2013, Volume: 98, Issue:9

    Topics: Animals; Blood Glucose; Cell Proliferation; Diabetes Mellitus, Type 2; Glucagon; Homeostasis; Humans; Hypoxia; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Mice; Mice, Inbred C57BL; Mitochondria; Models, Biological; Proinsulin; Reactive Oxygen Species; Sleep Apnea Syndromes

2013
Increasing glucagon secretion could antagonize the action of exogenous insulin for glycemic control in streptozocin-induced diabetic rhesus monkeys.
    Experimental biology and medicine (Maywood, N.J.), 2013, Volume: 238, Issue:4

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Glucagon; Glucagon-Secreting Cells; Hypoglycemic Agents; Insulin; Insulin Resistance; Longitudinal Studies; Macaca mulatta; Streptozocin; Time Factors; Treatment Outcome; Triglycerides

2013
Postprandial glucose fluxes and insulin sensitivity during exercise: a study in healthy individuals.
    American journal of physiology. Endocrinology and metabolism, 2013, Aug-15, Volume: 305, Issue:4

    Topics: Activities of Daily Living; Adult; Algorithms; Blood Glucose; C-Peptide; Carbon Radioisotopes; Deuterium; Feasibility Studies; Female; Glucagon; Gluconeogenesis; Glucose; Humans; Infusions, Intravenous; Insulin; Insulin Resistance; Male; Middle Aged; Models, Biological; Motor Activity; Postprandial Period; Tritium; Young Adult

2013
Long-term effects of bariatric surgery on meal disposal and β-cell function in diabetic and nondiabetic patients.
    Diabetes, 2013, Volume: 62, Issue:11

    Topics: Blood Glucose; Diabetes Mellitus, Type 2; Gastric Bypass; Glucagon; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Obesity; Obesity, Morbid; Weight Loss

2013
TAK-875, a GPR40/FFAR1 agonist, in combination with metformin prevents progression of diabetes and β-cell dysfunction in Zucker diabetic fatty rats.
    British journal of pharmacology, 2013, Volume: 170, Issue:3

    Topics: Animals; Benzofurans; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Glucagon; Glycated Hemoglobin; Homeodomain Proteins; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Metformin; Proliferating Cell Nuclear Antigen; Rats; Rats, Zucker; Receptors, G-Protein-Coupled; Sulfones; Time Factors; Trans-Activators

2013
Fgf21 impairs adipocyte insulin sensitivity in mice fed a low-carbohydrate, high-fat ketogenic diet.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: 3-Hydroxybutyric Acid; Adipocytes; Animals; Blood Glucose; Body Weight; Diet, Carbohydrate-Restricted; Diet, High-Fat; Fibroblast Growth Factors; Glucagon; Gluconeogenesis; Glucose Intolerance; Insulin; Insulin Resistance; Ketone Bodies; Liver; Male; Mice; Mice, Knockout; Phenotype; Phosphorylation; Proto-Oncogene Proteins c-akt

2013
Resveratrol prevents β-cell dedifferentiation in nonhuman primates given a high-fat/high-sugar diet.
    Diabetes, 2013, Volume: 62, Issue:10

    Topics: Animals; Blood Glucose; Body Weight; Cell Dedifferentiation; Densitometry; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Dietary Sucrose; Disease Models, Animal; Fluorescent Antibody Technique; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Glucose Tolerance Test; Glycated Hemoglobin; Homeobox Protein Nkx-2.2; Homeodomain Proteins; Insulin; Insulin Resistance; Insulin-Secreting Cells; Islets of Langerhans; Macaca mulatta; Nuclear Proteins; Protective Agents; Resveratrol; Sirtuin 1; Stilbenes; Transcription Factors

2013
Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects.
    The Journal of clinical investigation, 2013, Volume: 123, Issue:10

    Topics: Acetylation; Amino Acid Sequence; Anacardic Acids; Animals; Cells, Cultured; Conserved Sequence; Epigenesis, Genetic; Glucagon; Gluconeogenesis; Glucose; HEK293 Cells; Hepatocytes; Histones; Humans; Hypoglycemic Agents; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Liver; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Molecular Sequence Data; p300-CBP Transcription Factors; Protein Processing, Post-Translational; Proteins

2013
Roux-en-Y gastric bypass and sleeve gastrectomy: mechanisms of diabetes remission and role of gut hormones.
    The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:11

    Topics: Adult; Diabetes Mellitus, Type 2; Female; Gastrectomy; Gastric Bypass; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glycemic Index; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Islet Amyloid Polypeptide; Male; Middle Aged; Obesity, Morbid; Pancreatic Polypeptide; Peptide YY; Remission Induction

2013
A novel glucagon-like peptide-1 (GLP-1)/glucagon hybrid peptide with triple-acting agonist activity at glucose-dependent insulinotropic polypeptide, GLP-1, and glucagon receptors and therapeutic potential in high fat-fed mice.
    The Journal of biological chemistry, 2013, Dec-06, Volume: 288, Issue:49

    Topics: Amino Acid Sequence; Animals; Blood Glucose; Cyclic AMP; Diet, High-Fat; Dipeptidyl Peptidase 4; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Insulin; Insulin Resistance; Insulin Secretion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Molecular Sequence Data; Obesity; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Recombinant Fusion Proteins

2013
Serotonin 2C receptors in pro-opiomelanocortin neurons regulate energy and glucose homeostasis.
    The Journal of clinical investigation, 2013, Volume: 123, Issue:12

    Topics: Animals; Appetite Depressants; Body Weight; Dietary Fats; Dietary Sucrose; Drug Resistance; Energy Metabolism; Feeding Behavior; Female; Glucagon; Glucose; Homeostasis; Hyperglycemia; Hyperinsulinism; Hyperphagia; Insulin; Insulin Resistance; Insulin Secretion; Male; Mice; Mice, Knockout; Neurons; Obesity; Pro-Opiomelanocortin; Receptor, Serotonin, 5-HT2C; Recombinant Fusion Proteins; Serotonin; Serotonin Receptor Agonists

2013
Glucagon and insulin cord blood levels in very preterm, late preterm and full-term infants.
    Journal of pediatric endocrinology & metabolism : JPEM, 2014, Volume: 27, Issue:5-6

    Topics: Apgar Score; Cesarean Section; Female; Fetal Blood; Glucagon; Humans; Infant, Extremely Premature; Infant, Newborn; Infant, Premature; Insulin; Insulin Resistance; Male

2014
Co-agonist of glucagon and GLP-1 reduces cholesterol and improves insulin sensitivity independent of its effect on appetite and body weight in diet-induced obese C57 mice.
    Canadian journal of physiology and pharmacology, 2013, Volume: 91, Issue:12

    Topics: Animals; Appetite; Body Weight; Cholesterol; Cholesterol, LDL; Diet; Eating; Fibroblast Growth Factors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Gluconeogenesis; Insulin Resistance; Leptin; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Receptors, Glucagon; Triglycerides

2013
Low and high dietary protein:carbohydrate ratios during pregnancy affect materno-fetal glucose metabolism in pigs.
    The Journal of nutrition, 2014, Volume: 144, Issue:2

    Topics: Adaptation, Physiological; Animals; Area Under Curve; Blood Glucose; Brain; Diet; Diet, Carbohydrate-Restricted; Diet, Protein-Restricted; Dietary Carbohydrates; Dietary Proteins; Female; Fetal Development; Fetal Growth Retardation; Fetus; Glucagon; Gluconeogenesis; Glucose; Glucose Tolerance Test; Inositol; Insulin; Insulin Resistance; Lactic Acid; Liver; Placenta; Pregnancy; Pregnancy Complications; Prenatal Nutritional Physiological Phenomena; Protein Deficiency; Swine; Umbilicus

2014
Glucagon/insulin ratio in preoperative screening before pancreatic surgery: correlation with hemoglobin A1C in subjects with and without pancreatic cancer.
    Endocrine, 2014, Volume: 47, Issue:2

    Topics: Aged; Blood Glucose; C-Peptide; Female; Glucagon; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Pancreas; Pancreatic Neoplasms; Preoperative Period

2014
Effects of AMPK activation on insulin sensitivity and metabolism in leptin-deficient ob/ob mice.
    Diabetes, 2014, Volume: 63, Issue:5

    Topics: Acetyl-CoA Carboxylase; Adenylate Kinase; Animals; Female; Glucagon; Insulin; Insulin Resistance; Leptin; Lipid Metabolism; Male; Mice; Mice, Obese; Muscle, Skeletal; Obesity; Phosphorylation

2014
Glucose-induced glucagon-like Peptide 1 secretion is deficient in patients with non-alcoholic fatty liver disease.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Case-Control Studies; Fatty Liver; Female; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Non-alcoholic Fatty Liver Disease

2014
Incretin effect and glucagon responses to oral and intravenous glucose in patients with maturity-onset diabetes of the young--type 2 and type 3.
    Diabetes, 2014, Volume: 63, Issue:8

    Topics: Administration, Intravenous; Administration, Oral; Adult; Diabetes Mellitus, Type 2; Female; Gastric Emptying; Gastric Inhibitory Polypeptide; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 1; Glucokinase; Glucose; Hepatocyte Nuclear Factor 1-alpha; Humans; Incretins; Insulin Resistance; Male; Middle Aged

2014
Differential AMPK phosphorylation by glucagon and metformin regulates insulin signaling in human hepatic cells.
    Biochemical and biophysical research communications, 2014, May-16, Volume: 447, Issue:4

    Topics: AMP-Activated Protein Kinases; Cell Line; Cyclic AMP-Dependent Protein Kinases; Gene Knockdown Techniques; Glucagon; Hepatocytes; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Metformin; Phosphorylation; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Signal Transduction

2014
Alteration of the glucagon axis in GPR120 (FFAR4) knockout mice: a role for GPR120 in glucagon secretion.
    The Journal of biological chemistry, 2014, May-30, Volume: 289, Issue:22

    Topics: Animals; Calcium; Cells, Cultured; Fatty Acids; Fatty Acids, Unsaturated; Female; Glucagon; Glucagon-Secreting Cells; Humans; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, G-Protein-Coupled

2014
Clozapine directly increases insulin and glucagon secretion from islets: implications for impairment of glucose tolerance.
    Schizophrenia research, 2014, Volume: 157, Issue:1-3

    Topics: Animals; Antipsychotic Agents; Clozapine; Cyclobutanes; Epinephrine; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucose; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Liver; Male; Pancreas; Rats, Sprague-Dawley; Receptors, Glucagon; Sympathomimetics; Tissue Culture Techniques

2014
[Changes of plasma glucagon level in individuals with different glucose metabolism].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2014, Volume: 45, Issue:3

    Topics: Diabetes Mellitus, Type 2; Glucagon; Glucose; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance

2014
Role of endogenous GLP-1 and GIP in beta cell compensatory responses to insulin resistance and cellular stress.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Animals; Apoptosis; Cell Proliferation; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Hormones; Hydrocortisone; Insulin Resistance; Insulin-Secreting Cells; Islets of Langerhans; Lymphocytes; Male; Mice; Mice, Knockout; Pancreas; Protein Transport; Streptozocin

2014
Effects of delayed gastric emptying on postprandial glucose kinetics, insulin sensitivity, and β-cell function.
    American journal of physiology. Endocrinology and metabolism, 2014, Sep-15, Volume: 307, Issue:6

    Topics: Adolescent; Adult; Algorithms; Blood Glucose; C-Peptide; Female; Food; Gastric Emptying; Glucagon; Glucose; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Secreting Cells; Islet Amyloid Polypeptide; Kinetics; Male; Middle Aged; Young Adult

2014
PTEN deletion in pancreatic α-cells protects against high-fat diet-induced hyperglucagonemia and insulin resistance.
    Diabetes, 2015, Volume: 64, Issue:1

    Topics: Animals; Arginine; Diabetes Mellitus, Type 2; Diet, High-Fat; Female; Glucagon; Glucagon-Secreting Cells; Hyperglycemia; Insulin Resistance; Insulin-Secreting Cells; Male; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; Phosphatidylinositol 3-Kinases; PTEN Phosphohydrolase; RNA, Small Interfering; Signal Transduction

2015
Resveratrol ameliorates mitochondrial dysfunction but increases the risk of hypoglycemia following hemorrhagic shock.
    The journal of trauma and acute care surgery, 2014, Volume: 77, Issue:6

    Topics: Animals; Blood Glucose; Corticosterone; Glucagon; Glucagon-Like Peptide 1; Hypoglycemia; Insulin; Insulin Resistance; Kidney; Male; Mitochondria; Mitochondria, Liver; Rats, Long-Evans; Reactive Oxygen Species; Resuscitation; Resveratrol; Shock, Hemorrhagic; Stilbenes

2014
Maternal insulin resistance and transient hyperglycemia impact the metabolic and endocrine phenotypes of offspring.
    American journal of physiology. Endocrinology and metabolism, 2014, Nov-15, Volume: 307, Issue:10

    Topics: Animals; Animals, Newborn; Blood Glucose; Cell Proliferation; Diabetes, Gestational; Disease Models, Animal; Female; Glucagon; Glucagon-Like Peptide 1; Hyperglycemia; Hyperinsulinism; Insulin; Insulin Resistance; Insulin-Secreting Cells; Islets of Langerhans; Leptin; Mice; Organ Size; Phenotype; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Weight Gain

2014
Teneligliptin improves glycemic control with the reduction of postprandial insulin requirement in Japanese diabetic patients.
    Endocrine journal, 2015, Volume: 62, Issue:1

    Topics: Aged; Blood Glucose; Combined Modality Therapy; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Japan; Middle Aged; Monitoring, Ambulatory; Postprandial Period; Pyrazoles; Thiazolidines

2015
Cannabinoid receptor 1 antagonist treatment induces glucagon release and shows an additive therapeutic effect with GLP-1 agonist in diet-induced obese mice.
    Canadian journal of physiology and pharmacology, 2014, Volume: 92, Issue:12

    Topics: Animals; Anti-Obesity Agents; Blood Glucose; Body Weight; Diet, High-Fat; Drug Synergism; Eating; Exenatide; Glucagon; Glucagon-Like Peptide 1; Insulin Resistance; Male; Mice, Inbred C57BL; Mice, Obese; Obesity; Peptides; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Venoms

2014
Over-expression of Follistatin-like 3 attenuates fat accumulation and improves insulin sensitivity in mice.
    Metabolism: clinical and experimental, 2015, Volume: 64, Issue:2

    Topics: Activins; Adiposity; Animals; Diet, High-Fat; Female; Follistatin-Related Proteins; Glucagon; Glucose Intolerance; Insulin; Insulin Resistance; Islets of Langerhans; Liver; Mice, Inbred C57BL; Muscle Development; Muscle, Skeletal; Myostatin; Proteins; Random Allocation; Recombinant Proteins; Signal Transduction; Subcutaneous Fat; Up-Regulation

2015
Peripheral insulin resistance and impaired insulin signaling contribute to abnormal glucose metabolism in preterm baboons.
    Endocrinology, 2015, Volume: 156, Issue:3

    Topics: Animals; Blood Glucose; Female; Gene Expression Regulation; Glucagon; Glucose; Glucose Clamp Technique; Insulin Resistance; Muscle, Skeletal; Papio; Pregnancy; Premature Birth; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Signal Transduction; Vertebrobasilar Insufficiency

2015
Patients with psoriasis are insulin resistant.
    Journal of the American Academy of Dermatology, 2015, Volume: 72, Issue:4

    Topics: Adult; Anthropometry; Blood Glucose; C-Peptide; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Glucagon; Gluconeogenesis; Glucose Clamp Technique; Glucose Intolerance; Humans; Hyperinsulinism; Inflammation; Insulin; Insulin Resistance; Male; Middle Aged; Prediabetic State; Psoriasis; Risk

2015
Functional GIP receptors play a major role in islet compensatory response to high fat feeding in mice.
    Biochimica et biophysica acta, 2015, Volume: 1850, Issue:6

    Topics: Adaptation, Physiological; Adiposity; Animals; Apoptosis; Blood Glucose; Cell Proliferation; Diet, High-Fat; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Insulin; Insulin Resistance; Intestinal Mucosa; Islets of Langerhans; Male; Mice, Inbred C57BL; Mice, Knockout; Receptors, Gastrointestinal Hormone; Time Factors

2015
Increment of serum C-peptide measured by glucagon test closely correlates with human relative beta-cell area.
    Endocrine journal, 2015, Volume: 62, Issue:4

    Topics: Aged; Blood Glucose; C-Peptide; Cell Count; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin Resistance; Insulin-Secreting Cells; Male; Middle Aged

2015
Islet adaptation to obesity and insulin resistance in WNIN/GR-Ob rats.
    Islets, 2014, Volume: 6, Issue:5-6

    Topics: Adaptation, Physiological; Age Factors; Animals; Body Weight; Female; Gene Expression; Glucagon; Insulin; Insulin Resistance; Insulin-Secreting Cells; Islets of Langerhans; Microscopy, Electron, Scanning; Obesity; Organ Size; Oxidative Stress; Rats; Rats, Mutant Strains; Somatostatin

2014
Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion.
    Nature medicine, 2015, Volume: 21, Issue:5

    Topics: Administration, Oral; Adult; Animals; Benzhydryl Compounds; Blood Glucose; Cell Separation; Female; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation; Gene Silencing; Glucagon; Glucagon-Secreting Cells; Gluconeogenesis; Glucosides; Hepatocyte Nuclear Factor 4; Humans; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; RNA, Small Interfering; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2

2015
Incretin secretion in obese Korean children and adolescents with newly diagnosed type 2 diabetes.
    Clinical endocrinology, 2016, Volume: 84, Issue:1

    Topics: Adolescent; Analysis of Variance; Asian People; Blood Glucose; Body Mass Index; C-Peptide; Case-Control Studies; Child; Diabetes Mellitus, Type 2; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Humans; Incretins; Insulin; Insulin Resistance; Male; Obesity; Republic of Korea

2016
Relationship between circadian blood pressure variability and function of islet α and β cell in type 2 diabetes with dyssomnia.
    Journal of diabetes and its complications, 2015, Volume: 29, Issue:5

    Topics: Administration, Oral; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Diabetes Mellitus, Type 2; Dyssomnias; Female; Glucagon; Glucagon-Secreting Cells; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Middle Aged; Prehypertension; Retrospective Studies

2015
Acute glucagon induces postprandial peripheral insulin resistance.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Adenylyl Cyclases; Animals; Blood Glucose; Bucladesine; Cyclic AMP; Dose-Response Relationship, Drug; Glucagon; Glucose Clamp Technique; Glutathione; Injections, Intravenous; Insulin; Insulin Resistance; Liver; Male; Nitric Oxide; omega-N-Methylarginine; Portal Vein; Postprandial Period; Rats; Rats, Sprague-Dawley

2015
Hydrolysis enhances bioavailability of proanthocyanidin-derived metabolites and improves β-cell function in glucose intolerant rats.
    The Journal of nutritional biochemistry, 2015, Volume: 26, Issue:8

    Topics: Animals; Biological Availability; Blood Glucose; Body Composition; Diet, Fat-Restricted; Diet, High-Fat; Dietary Supplements; Glucagon; Glucose Tolerance Test; Hydrolysis; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Proanthocyanidins; Rats; Rats, Sprague-Dawley

2015
KBP-042 improves bodyweight and glucose homeostasis with indices of increased insulin sensitivity irrespective of route of administration.
    European journal of pharmacology, 2015, Sep-05, Volume: 762

    Topics: Adiposity; Animals; Blood Glucose; Body Weight; Calcitonin; Diet, High-Fat; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Homeostasis; Insulin Resistance; Intra-Abdominal Fat; Islet Amyloid Polypeptide; Leptin; Male; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Calcitonin

2015
[Association between sleep disorders and dawn phenomenon in patients with type 2 diabetes mellitus].
    Zhonghua yi xue za zhi, 2015, Apr-28, Volume: 95, Issue:16

    Topics: Diabetes Mellitus, Type 2; Glucagon; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Sleep Wake Disorders

2015
Sustained treatment with a stable long-acting oxyntomodulin analogue improves metabolic control and islet morphology in an experimental model of type 1 diabetes.
    Diabetes, obesity & metabolism, 2015, Volume: 17, Issue:9

    Topics: Animals; Apoptosis; Blood Glucose; Cell Proliferation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Eating; Gastrointestinal Hormones; Glucagon; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Mice; Oxyntomodulin; Pancreas

2015
The frog skin host-defense peptide CPF-SE1 improves glucose tolerance, insulin sensitivity and islet function and decreases plasma lipids in high-fat fed mice.
    European journal of pharmacology, 2015, Oct-05, Volume: 764

    Topics: Amino Acid Sequence; Animals; Anura; Blood Glucose; Body Composition; Body Weight; Diet, High-Fat; Energy Intake; Glucagon; Glucose Tolerance Test; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Lipids; Male; Mice; Molecular Sequence Data; Peptides; Skin

2015
[I10W]tigerinin-1R enhances both insulin sensitivity and pancreatic beta cell function and decreases adiposity and plasma triglycerides in high-fat mice.
    Acta diabetologica, 2016, Volume: 53, Issue:2

    Topics: Adiposity; Animals; Antimicrobial Cationic Peptides; Blood Glucose; Body Composition; Diet, High-Fat; Glucagon; Glucose Tolerance Test; Hypoglycemic Agents; Insulin Resistance; Insulin-Secreting Cells; Lipids; Male; Mice; Obesity; Peptides; Triglycerides

2016
The Zinc Transporter Slc30a8/ZnT8 Is Required in a Subpopulation of Pancreatic α-Cells for Hypoglycemia-induced Glucagon Secretion.
    The Journal of biological chemistry, 2015, Aug-28, Volume: 290, Issue:35

    Topics: Animals; Cation Transport Proteins; Cells, Cultured; Female; Gene Deletion; Glucagon; Glucagon-Secreting Cells; Glucose; Hypoglycemia; Insulin Resistance; Mice, Inbred C57BL; Zinc; Zinc Transporter 8

2015
Hepatic insulin resistance and increased hepatic glucose production in mice lacking Fgf21.
    The Journal of endocrinology, 2015, Volume: 226, Issue:3

    Topics: Animals; Blood Glucose; Energy Metabolism; Fibroblast Growth Factors; Glucagon; Gluconeogenesis; Glucose; Glycogen; Insulin Resistance; Lipids; Liver; Male; Mice; Mice, Knockout

2015
Cross-sectional and Longitudinal Analyses of Factors Contributing to the Progressive Loss of the β-cell Function in Type 2 Diabetes.
    Internal medicine (Tokyo, Japan), 2015, Volume: 54, Issue:16

    Topics: Adult; Aged; Body Mass Index; C-Peptide; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Disease Progression; Female; Glucagon; Glycated Hemoglobin; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Longitudinal Studies; Male; Middle Aged; Overweight; Regression Analysis; Thinness; Triglycerides

2015
Ileal Transposition Decreases Plasma Lipopolysaccharide Levels in Association with Increased L Cell Secretion in Non-obese Non-diabetic Rats.
    Obesity surgery, 2016, Volume: 26, Issue:6

    Topics: Animals; Blood Glucose; Body Weight; Drinking; Eating; Enteroendocrine Cells; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucose Tolerance Test; Ileum; Insulin Resistance; Lipopolysaccharides; Male; Obesity, Morbid; Peptide YY; Rats, Sprague-Dawley

2016
Postprandial glucose, insulin, and glucagon-like peptide-1 responses of different equine breeds adapted to meals containing micronized maize.
    Journal of animal science, 2015, Volume: 93, Issue:7

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Blood Glucose; Breeding; Diet; Food Handling; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Horses; Insulin; Insulin Resistance; Postprandial Period; Zea mays

2015
Prediabetes linked to excess glucagon in transgenic mice with pancreatic active AKT1.
    The Journal of endocrinology, 2016, Volume: 228, Issue:1

    Topics: Animals; Blood Glucose; Diabetes Mellitus; Enzyme Activation; Fasting; Genotype; Glucagon; Glucose; Glucose Intolerance; Homeostasis; Hyperglycemia; Insulin; Insulin Resistance; Mice; Mice, Transgenic; Myristic Acids; Pancreas; Prediabetic State; Proto-Oncogene Proteins c-akt

2016
TCF7L2 Genotype and α-Cell Function in Humans Without Diabetes.
    Diabetes, 2016, Volume: 65, Issue:2

    Topics: Adult; Aged; Alleles; Cohort Studies; Diabetes Mellitus; Emulsions; Fatty Acids, Nonesterified; Female; Genetic Variation; Genotype; Glucagon; Glucagon-Secreting Cells; Glucose Tolerance Test; Glycerol; Humans; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Middle Aged; Phospholipids; Soybean Oil; Transcription Factor 7-Like 2 Protein

2016
Enhanced insulin sensitivity mediated by adipose tissue browning perturbs islet morphology and hormone secretion in response to autonomic nervous activation in female mice.
    American journal of physiology. Endocrinology and metabolism, 2016, Jan-01, Volume: 310, Issue:1

    Topics: Adipose Tissue, Brown; Animals; Autonomic Nervous System; Cell Shape; Cell Transdifferentiation; Female; Forkhead Transcription Factors; Glucagon; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic

2016
Comparison of gut hormones and adipokines stimulated by glucagon test among patients with type II diabetes mellitus after metabolic surgery.
    Neuropeptides, 2016, Volume: 55

    Topics: Adipokines; Adult; Aged; Bariatric Surgery; Blood Glucose; Diabetes Mellitus, Type 2; Female; Gastric Bypass; Gastrointestinal Hormones; Glucagon; Humans; Insulin Resistance; Male; Middle Aged; Obesity, Morbid

2016
The effect of 8 days of strict bed rest on the incretin effect in healthy volunteers.
    Journal of applied physiology (Bethesda, Md. : 1985), 2016, Mar-15, Volume: 120, Issue:6

    Topics: Adolescent; Adult; Bed Rest; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucose; Glucose Tolerance Test; Healthy Volunteers; Humans; Incretins; Insulin; Insulin Resistance; Male; Young Adult

2016
[Association between retinopathy and sleep disorder in patients with type 2 diabetes mellitus].
    Zhonghua yi xue za zhi, 2015, Aug-25, Volume: 95, Issue:32

    Topics: Blood Glucose; Diabetes Mellitus, Type 2; Glucagon; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Postprandial Period; Sleep Wake Disorders

2015
A Transient Metabolic Recovery from Early Life Glucose Intolerance in Cystic Fibrosis Ferrets Occurs During Pancreatic Remodeling.
    Endocrinology, 2016, Volume: 157, Issue:5

    Topics: Animals; Blood Glucose; Cystic Fibrosis; Cytokines; Female; Ferrets; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Hyperglycemia; Insulin; Insulin Resistance; Male; Pancreas

2016
Differential effects of once-weekly glucagon-like peptide-1 receptor agonist dulaglutide and metformin on pancreatic β-cell and insulin sensitivity during a standardized test meal in patients with type 2 diabetes.
    Diabetes, obesity & metabolism, 2016, Volume: 18, Issue:8

    Topics: Adult; Aged; Area Under Curve; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Immunoglobulin Fc Fragments; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Metformin; Middle Aged; Postprandial Period; Recombinant Fusion Proteins; Treatment Outcome

2016
Glucagon receptor antagonist and GIP agonist combination for diet-induced obese mice.
    The Journal of endocrinology, 2016, Volume: 229, Issue:3

    Topics: Animals; Cell Line; Cyclic AMP; Diabetes Mellitus, Type 2; Diet, High-Fat; Energy Metabolism; Gastric Inhibitory Polypeptide; Glucagon; Insulin; Insulin Resistance; Insulin Secretion; Male; Mice; Mice, Obese; Motor Activity; Obesity; Rats; Receptors, Glucagon

2016
Relationship between pancreatic hormones and glucose metabolism: A cross-sectional study in patients after acute pancreatitis.
    American journal of physiology. Gastrointestinal and liver physiology, 2016, 07-01, Volume: 311, Issue:1

    Topics: Acute Disease; Adult; Aged; Biomarkers; Blood Glucose; Chi-Square Distribution; Cross-Sectional Studies; Fasting; Female; Glucagon; Glycated Hemoglobin; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Islet Amyloid Polypeptide; Linear Models; Male; Middle Aged; Multivariate Analysis; Pancreatic Hormones; Pancreatic Polypeptide; Pancreatitis; Somatostatin

2016
Utility of C-peptide for a reliable estimate of insulin secretion in children with growth hormone deficiency.
    Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 2016, Volume: 29

    Topics: Area Under Curve; C-Peptide; Case-Control Studies; Child; Child, Preschool; Fasting; Female; Glucagon; Glucose Tolerance Test; Hormones; Human Growth Hormone; Humans; Hypopituitarism; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Like Growth Factor I; Insulin-Secreting Cells; Male; Prospective Studies

2016
Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production.
    Cell metabolism, 2016, Jun-14, Volume: 23, Issue:6

    Topics: Adipose Tissue; Animals; Diet; Efferent Pathways; Fatty Acids, Nonesterified; Forkhead Box Protein O1; Gene Deletion; Gene Expression Regulation; Glucagon; Glucokinase; Gluconeogenesis; Glucose; Glucose Tolerance Test; Heparin; Hepatocytes; Insulin; Insulin Resistance; Lipogenesis; Liver; Male; Mechanistic Target of Rapamycin Complex 1; Mice, Knockout; Multiprotein Complexes; Postprandial Period; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases; Vagus Nerve

2016
Effects of flavonoid-rich Chinese bayberry (Morella rubra Sieb. et Zucc.) fruit extract on regulating glucose and lipid metabolism in diabetic KK-A(y) mice.
    Food & function, 2016, Jul-13, Volume: 7, Issue:7

    Topics: Animals; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Flavonoids; Fruit; Glucagon; Glucose-6-Phosphatase; Glutathione Peroxidase; Hep G2 Cells; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Lipid Metabolism; Lipids; Liver; Mice; Myrica; Organ Size; Plant Extracts; Transcription Factors

2016
Dogfish glucagon analogues counter hyperglycaemia and enhance both insulin secretion and action in diet-induced obese diabetic mice.
    Diabetes, obesity & metabolism, 2016, Volume: 18, Issue:10

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diet, High-Fat; Dogfish; Glucagon; Glucose Tolerance Test; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Mice; Mice, Obese; Obesity

2016
Exenatide Treatment Alone Improves β-Cell Function in a Canine Model of Pre-Diabetes.
    PloS one, 2016, Volume: 11, Issue:7

    Topics: Animals; Blood Glucose; Body Composition; Disease Models, Animal; Dogs; Eating; Energy Metabolism; Exenatide; Fasting; Glucagon; Glucose Tolerance Test; Glycated Hemoglobin; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Secreting Cells; Liver; Male; Peptides; Prediabetic State; Venoms

2016
Male Men1 heterozygous mice exhibit fasting hyperglycemia in the early stage of MEN1.
    The Journal of endocrinology, 2016, Volume: 230, Issue:3

    Topics: Animals; Fasting; Glucagon; Gluconeogenesis; Heterozygote; Hyperglycemia; Insulin Resistance; Islets of Langerhans; Liver; Male; Mice; Mice, Mutant Strains; Multiple Endocrine Neoplasia Type 1

2016
Influence of a HTR2B Stop Codon on Glucagon Homeostasis and Glucose Excursion in Non-Diabetic Men.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2016, Volume: 124, Issue:9

    Topics: Adult; Blood Glucose; Cohort Studies; Finland; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Male; Receptor, Serotonin, 5-HT2B

2016
Insulin Resistance Is Accompanied by Increased Fasting Glucagon and Delayed Glucagon Suppression in Individuals With Normal and Impaired Glucose Regulation.
    Diabetes, 2016, Volume: 65, Issue:11

    Topics: Aged; Blood Glucose; Cohort Studies; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Prediabetic State

2016
Insulin resistance, glucagon-like peptide-1 and factors influencing glucose homeostasis in neonates.
    Archives of disease in childhood. Fetal and neonatal edition, 2017, Volume: 102, Issue:2

    Topics: Blood Glucose; C-Peptide; Female; Glucagon; Glucagon-Like Peptide 1; Homeostasis; Humans; Infant, Newborn; Infant, Premature; Insulin; Insulin Resistance; Intensive Care Units, Neonatal; Male; New Zealand

2017
TSC1-mTOR signaling determines the differentiation of islet cells.
    The Journal of endocrinology, 2017, Volume: 232, Issue:1

    Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Blood Glucose; Cell Differentiation; Diet, High-Fat; Glucagon; Glucose Clamp Technique; Glucose Intolerance; Insulin; Insulin Resistance; Islets of Langerhans; Mice; Mice, Knockout; Nerve Tissue Proteins; Signal Transduction; Somatostatin; Telomerase; TOR Serine-Threonine Kinases

2017
Brain GLUT4 Knockout Mice Have Impaired Glucose Tolerance, Decreased Insulin Sensitivity, and Impaired Hypoglycemic Counterregulation.
    Diabetes, 2017, Volume: 66, Issue:3

    Topics: Animals; Blood Glucose; Blotting, Western; Brain; Diet, High-Fat; Epinephrine; Glucagon; Glucose; Glucose Clamp Technique; Glucose Intolerance; Glucose Tolerance Test; Glucose Transporter Type 4; Homeostasis; Hypoglycemia; Hypothalamus; In Vitro Techniques; Indinavir; Insulin Resistance; Male; Mice; Mice, Knockout; Neurons; Paraventricular Hypothalamic Nucleus; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley

2017
Improvement in insulin sensitivity following intensive insulin therapy and association of glucagon with long-term diabetes remission.
    The Journal of international medical research, 2016, Volume: 44, Issue:6

    Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Middle Aged; Remission Induction

2016
Nonsuppressed Glucagon After Glucose Challenge as a Potential Predictor for Glucose Tolerance.
    Diabetes, 2017, Volume: 66, Issue:5

    Topics: Adult; Aged; Cohort Studies; Diabetes Mellitus, Type 2; Diet Therapy; Exercise; Female; Finland; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin Resistance; Life Style; Longitudinal Studies; Male; Middle Aged

2017
The impact of kidney transplantation on insulin sensitivity.
    Transplant international : official journal of the European Society for Organ Transplantation, 2017, Volume: 30, Issue:3

    Topics: Adult; Blood Glucose; Body Composition; Case-Control Studies; Female; Glucagon; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Kidney Transplantation; Lipolysis; Living Donors; Male; Middle Aged; Time Factors; Young Adult

2017
Glucagon receptor inhibition normalizes blood glucose in severe insulin-resistant mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2017, 03-07, Volume: 114, Issue:10

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Glucagon-Secreting Cells; Humans; Hyperglycemia; Insulin; Insulin Resistance; Insulin-Secreting Cells; Ketosis; Mice; Mutation; Peptides; Receptor, Insulin; Receptors, Glucagon

2017
Effects of a Novel Glucokinase Activator, HMS5552, on Glucose Metabolism in a Rat Model of Type 2 Diabetes Mellitus.
    Journal of diabetes research, 2017, Volume: 2017

    Topics: Animals; Blood Glucose; Carbohydrate Metabolism; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucagon; Glucokinase; Glucose Tolerance Test; Insulin; Insulin Resistance; Male; Rats; Rats, Sprague-Dawley; Triglycerides

2017
Gastric bypass in the pig increases GIP levels and decreases active GLP-1 levels.
    Peptides, 2017, Volume: 90

    Topics: Animals; Diabetes Mellitus, Type 2; Female; Gastric Bypass; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Obesity; Sus scrofa

2017
β-Cell Inactivation of
    Diabetes, 2017, Volume: 66, Issue:6

    Topics: Adipokines; Animals; Apoptosis; Blood Glucose; Diabetes Mellitus, Experimental; Diet, High-Fat; Gene Expression Profiling; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Tolerance Test; Incretins; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Mice, Knockout; Oxadiazoles; Pyrimidines; Receptors, G-Protein-Coupled

2017
The Characteristics of Hepatic Gsα-cAMP Axis in HSHF Diet-Fed Obese Insulin Resistance Rats and Genetic Diabetic Mice.
    Biological & pharmaceutical bulletin, 2017, Jun-01, Volume: 40, Issue:6

    Topics: Animals; Blood Glucose; Cyclic AMP; Diabetes Mellitus; Diet, High-Fat; Dietary Sugars; Disease Models, Animal; Glucagon; GTP-Binding Protein alpha Subunits; Insulin; Insulin Resistance; Liver; Male; Mice, Inbred C57BL; Obesity; Rats, Wistar

2017
Spontaneous diabetes in hemizygous human amylin transgenic mice that developed neither islet amyloid nor peripheral insulin resistance.
    Diabetes, 2008, Volume: 57, Issue:10

    Topics: Amyloid; Animals; Apoptosis; Blood Glucose; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Glucagon; Glucose; Glucose Tolerance Test; Humans; Immunohistochemistry; Insulin Resistance; Islet Amyloid Polypeptide; Islets of Langerhans; Mice; Mice, Inbred Strains; Mice, Transgenic; Microscopy, Electron, Transmission; Somatostatin

2008
Effects of pioglitazone and metformin on NEFA-induced insulin resistance in type 2 diabetes.
    Diabetologia, 2008, Volume: 51, Issue:11

    Topics: Blood Glucose; Body Mass Index; C-Peptide; Diabetes Mellitus, Type 2; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Female; Glucagon; Gluconeogenesis; Glucose; Glucose Clamp Technique; Glycerol; Heparin; Humans; Insulin; Insulin Resistance; Male; Metformin; Middle Aged; Pioglitazone; Thiazolidinediones

2008
Development and characterization of a novel rat model of type 2 diabetes mellitus: the UC Davis type 2 diabetes mellitus UCD-T2DM rat.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 295, Issue:6

    Topics: Adipokines; Adiposity; Age Factors; Aging; Animals; Blood Glucose; Crosses, Genetic; Diabetes Mellitus, Type 2; Disease Models, Animal; Disease Progression; Female; Fertility; Ghrelin; Glucagon; Glucose Intolerance; Insulin; Insulin Resistance; Insulin-Secreting Cells; Intra-Abdominal Fat; Lipids; Male; Obesity; Rats; Rats, Sprague-Dawley; Rats, Zucker; Triglycerides

2008
A lipid-parameter-based index for estimating insulin sensitivity and identifying insulin resistance in a healthy population.
    Diabetes & metabolism, 2008, Volume: 34, Issue:5

    Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Blood Glucose; Body Mass Index; Fasting; Fatty Acids, Nonesterified; Glucagon; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Lipids; Middle Aged; Proinsulin; Reference Values; Waist-Hip Ratio

2008
Hepatic glucose production and insulin resistance.
    Wiener medizinische Wochenschrift (1946), 2008, Volume: 158, Issue:19-20

    Topics: Adipokines; Animals; Blood Glucose; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Gluconeogenesis; Glycogenolysis; Insulin; Insulin Resistance; Insulin-Like Growth Factor I; Leptin; Liver; Male; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Signal Transduction; Triglycerides

2008
Visceral fat and adiponectin: associations with insulin resistance are tissue-specific in women.
    Metabolic syndrome and related disorders, 2009, Volume: 7, Issue:1

    Topics: Absorptiometry, Photon; Adiponectin; Adiposity; Blood Glucose; Body Mass Index; Enzyme-Linked Immunosorbent Assay; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Intra-Abdominal Fat; Liver; Middle Aged; Muscle, Skeletal; Obesity; Octreotide; Postmenopause; Time Factors; Tomography, X-Ray Computed

2009
Transgenic expression of insulin-response element binding protein-1 in beta-cells reproduces type 2 diabetes.
    Endocrinology, 2009, Volume: 150, Issue:6

    Topics: Animals; Cells, Cultured; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Glucagon-Secreting Cells; Glucose; Hyperinsulinism; Insulin; Insulin Resistance; Insulin-Secreting Cells; Iron Regulatory Protein 1; Mice; Mice, Transgenic; Obesity; Phenotype; Rats; Rats, Zucker; Somatostatin-Secreting Cells

2009
Effects of insulin on ketogenesis following fasting in lean and obese men.
    Obesity (Silver Spring, Md.), 2009, Volume: 17, Issue:7

    Topics: Adolescent; Adult; Blood Glucose; Body Mass Index; Body Weight; Energy Metabolism; Epinephrine; Fasting; Fatty Acids, Nonesterified; Glucagon; Humans; Hydrocortisone; Insulin; Insulin Resistance; Ketone Bodies; Male; Middle Aged; Obesity; Thinness; Young Adult

2009
Fibroblast growth factor 21 controls glycemia via regulation of hepatic glucose flux and insulin sensitivity.
    Endocrinology, 2009, Volume: 150, Issue:9

    Topics: Animals; Blood Glucose; Fasting; Fibroblast Growth Factors; Glucagon; Insulin Resistance; Liver; Liver Glycogen; Male; Mice; Mice, Obese

2009
Mechanisms to conserve glucose in lactating women during a 42-h fast.
    American journal of physiology. Endocrinology and metabolism, 2009, Volume: 297, Issue:4

    Topics: Adult; Algorithms; Blood Glucose; C-Peptide; Calorimetry, Indirect; Diet; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Gluconeogenesis; Glucose; Hexoses; Humans; Insulin; Insulin Resistance; Isotope Labeling; Ketone Bodies; Kinetics; Lactates; Lactation; Milk, Human; Oxidation-Reduction

2009
Clozapine and quetiapine acutely reduce glucagon-like peptide-1 production and increase glucagon release in obese rats: implications for glucose metabolism and food choice behaviour.
    Schizophrenia research, 2009, Volume: 115, Issue:1

    Topics: Analysis of Variance; Animals; Antipsychotic Agents; Body Composition; Body Weight; Clozapine; Dibenzothiazepines; Dietary Fats; Disease Models, Animal; Eating; Exenatide; Food Preferences; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Tolerance Test; Hypoglycemic Agents; Insulin Resistance; Male; Obesity; Peptides; Pyrazines; Quetiapine Fumarate; Rats; Rats, Sprague-Dawley; Sitagliptin Phosphate; Triazoles; Venoms

2009
On the diagnosis and investigation of adrenal insufficiency in adults.
    Annals of clinical biochemistry, 2010, Volume: 47, Issue:Pt 1

    Topics: Adrenal Insufficiency; Adult; Diagnostic Techniques, Endocrine; Glucagon; Humans; Hypothalamic Diseases; Insulin Resistance; Metyrapone; Pituitary Diseases; Prognosis; Reference Values

2010
Chronic hepatitis C is associated with peripheral rather than hepatic insulin resistance.
    Gastroenterology, 2010, Volume: 138, Issue:3

    Topics: Acute-Phase Proteins; Adiposity; Adult; Australia; Biomarkers; Blood Glucose; Case-Control Studies; China; Cross-Sectional Studies; England; Genotype; Glucagon; Glucose Clamp Technique; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin; Insulin Resistance; Intra-Abdominal Fat; Lipocalin-2; Lipocalins; Liver; Magnetic Resonance Spectroscopy; Male; Middle Aged; Muscle, Skeletal; Proto-Oncogene Proteins; Receptors, Tumor Necrosis Factor, Type II; RNA, Viral; Subcutaneous Fat; Time Factors; Viral Load

2010
Metabolic effects of free fatty acids during endotoxaemia in a porcine model--free fatty acid inhibition of growth hormone secretion as a potential catabolic feedback mechanism.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2010, Volume: 42, Issue:5

    Topics: Animals; Endotoxemia; Endotoxins; Epinephrine; Fatty Acids, Nonesterified; Feedback, Physiological; Female; Glucagon; Glucose; Growth Hormone; Hydrocortisone; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipopolysaccharides; Norepinephrine; Swine

2010
[Expression of glucagon in gestational and diet-induced hyperlipidemic gestational rats].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2010, Volume: 26, Issue:4

    Topics: Animals; Blood Glucose; Diet; Female; Gene Expression Regulation; Glucagon; Glucose Tolerance Test; Hyperlipidemias; Insulin; Insulin Resistance; Pancreas; Polymerase Chain Reaction; Pregnancy; Pregnancy Complications; Rats; RNA, Messenger

2010
Hyperinsulinemic euglycemic step clamping with tracer glucose infusion and labeled glucose infusate for assessment of acute insulin resistance in pigs.
    American journal of physiology. Endocrinology and metabolism, 2010, Volume: 298, Issue:6

    Topics: Animals; C-Peptide; Chromatography, Liquid; Dose-Response Relationship, Drug; Glucagon; Glucose; Glucose Clamp Technique; Hydrocortisone; Insulin; Insulin Resistance; Kinetics; Liver; Male; Swine; Tandem Mass Spectrometry

2010
Reduced glucose tolerance and insulin resistance induced by steroid treatment, relative physical inactivity, and high-calorie diet impairs the incretin effect in healthy subjects.
    The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:7

    Topics: Adult; Area Under Curve; Blood Glucose; Body Weight; C-Peptide; Diet; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Humans; Incretins; Insulin; Insulin Resistance; Male; Motor Activity; Prednisolone

2010
Insulin sensitivity and body composition in cirrhosis: changes after TIPS.
    American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 299, Issue:2

    Topics: Body Composition; C-Peptide; Diabetes Mellitus; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glucose Clamp Technique; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin Resistance; Liver; Liver Cirrhosis; Male; Middle Aged; Portasystemic Shunt, Transjugular Intrahepatic; Predictive Value of Tests; Rest

2010
Increased beta-cell mass by islet transplantation and PLAG1 overexpression causes hyperinsulinemic normoglycemia and hepatic insulin resistance in mice.
    Diabetes, 2010, Volume: 59, Issue:8

    Topics: Animals; Blood Glucose; Cell Division; DNA-Binding Proteins; Gene Expression Regulation; Glucagon; Glucose Clamp Technique; Glucose Tolerance Test; Homeostasis; Hyperinsulinism; Insulin; Insulin Resistance; Insulin-Secreting Cells; Islets of Langerhans Transplantation; Mice; Mice, Inbred C57BL; Mice, Transgenic

2010
Combination peroxisome proliferator-activated receptor gamma and alpha agonist treatment in Type 2 diabetes prevents the beneficial pioglitazone effect on liver fat content.
    Diabetic medicine : a journal of the British Diabetic Association, 2010, Volume: 27, Issue:2

    Topics: Abdominal Muscles; Adult; Aged; Bezafibrate; Blood Glucose; Body Weight; C-Peptide; Diabetes Mellitus, Type 2; Glucagon; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Insulin Resistance; Liver; Middle Aged; Pioglitazone; PPAR alpha; PPAR gamma; Thiazolidinediones; Triglycerides

2010
Glucose homeostasis in pre-diabetic NOD and lymphocyte-deficient NOD/SCID mice during gestation.
    The review of diabetic studies : RDS, 2010,Spring, Volume: 7, Issue:1

    Topics: Animals; Blood Glucose; Corticosterone; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Homeostasis; Insulin; Insulin Resistance; Islets of Langerhans; Lymphocytes; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, SCID; Pancreas; Prediabetic State; Pregnancy; Pregnancy in Diabetics

2010
Pathogenesis of fasting and postprandial hyperglycemia in type 2 diabetes: implications for therapy.
    Diabetes, 2010, Volume: 59, Issue:11

    Topics: Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Glucagon; Gluconeogenesis; Glucose; Glycosuria; Humans; Hyperglycemia; Insulin Resistance; Intestinal Absorption; Liver; Postprandial Period; Reference Values; Uridine Diphosphate Glucose

2010
Systemic energy homeostasis in Huntington's disease patients.
    Journal of neurology, neurosurgery, and psychiatry, 2010, Volume: 81, Issue:11

    Topics: Adult; Blood Glucose; Calorimetry, Indirect; Energy Metabolism; Female; Glucagon; Glucose Clamp Technique; Homeostasis; Humans; Huntingtin Protein; Huntington Disease; Insulin; Insulin Resistance; Lipid Metabolism; Male; Middle Aged; Nerve Tissue Proteins; Nuclear Proteins; Signal Transduction; Trinucleotide Repeats

2010
Distinguishing among incretin-based therapies. Glucose-lowering effects of incretin-based therapies.
    The Journal of family practice, 2010, Volume: 59, Issue:9 Suppl 1

    Topics: Adamantane; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Exenatide; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Incretins; Insulin; Insulin Resistance; Liraglutide; Male; Metformin; Middle Aged; Peptides; Pyrazines; Receptors, Glucagon; Sitagliptin Phosphate; Triazoles; Venoms

2010
Distinguishing among incretin-based therapies. Patient education and self-management.
    The Journal of family practice, 2010, Volume: 59, Issue:9 Suppl 1

    Topics: Adamantane; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Exenatide; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Incretins; Insulin; Insulin Resistance; Liraglutide; Male; Metformin; Middle Aged; Patient Education as Topic; Peptides; Pyrazines; Receptors, Glucagon; Self Care; Sitagliptin Phosphate; Triazoles; Venoms

2010
Basal alpha-cell up-regulation in obese insulin-resistant adolescents.
    The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:1

    Topics: Adolescent; Analysis of Variance; Area Under Curve; Blood Glucose; C-Peptide; Glucagon; Glucagon-Secreting Cells; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Obesity; Regression Analysis; Up-Regulation; Young Adult

2011
Increased postprandial GIP and glucagon responses, but unaltered GLP-1 response after intervention with steroid hormone, relative physical inactivity, and high-calorie diet in healthy subjects.
    The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:2

    Topics: Adult; Area Under Curve; Blood Glucose; C-Peptide; Diet; Energy Intake; Fasting; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Motor Activity; Postprandial Period; Prednisolone; Young Adult

2011
Pre-treatment with a DPP-4 inhibitor is infarct sparing in hearts from obese, pre-diabetic rats.
    Cardiovascular drugs and therapy, 2011, Volume: 25, Issue:1

    Topics: Animals; Blood Glucose; Body Weight; Cardiotonic Agents; Dipeptidyl-Peptidase IV Inhibitors; Glucagon; Glucagon-Like Peptide 1; Insulin; Insulin Resistance; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; Obesity; Pancreas; Phosphotransferases; Prediabetic State; Rats; Rats, Wistar

2011
Proinsulin/C-peptide ratio, glucagon and remission in new-onset Type 1 diabetes mellitus in young adults.
    Diabetic medicine : a journal of the British Diabetic Association, 2011, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Biomarkers; C-Peptide; Diabetes Mellitus, Type 1; Disease Progression; Fasting; Female; Glucagon; Glycated Hemoglobin; Humans; Insulin Resistance; Male; Proinsulin; Prospective Studies; Reference Values; Remission Induction; Young Adult

2011
Evaluation of beta-cell sensitivity to glucose and first-phase insulin secretion in obese dogs.
    American journal of veterinary research, 2011, Volume: 72, Issue:3

    Topics: Animals; Blood Glucose; Dog Diseases; Dogs; Glucagon; Glucose Tolerance Test; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Obesity

2011
Dual modulation of GIP and glucagon action by the low molecular weight compound 4-hydroxybenzoic acid 2-bromobenzylidene hydrazide.
    Diabetes, obesity & metabolism, 2011, Volume: 13, Issue:8

    Topics: Adipokines; Animals; Benzene Derivatives; Gastric Inhibitory Polypeptide; Glucagon; Hydrocarbons, Brominated; Insulin Resistance; Male; Mice; Obesity; Parabens; Receptors, Gastrointestinal Hormone

2011
Divergent effects of GLP-1 analogs exendin-4 and exendin-9 on the expression of myosin heavy chain isoforms in C2C12 myotubes.
    Peptides, 2011, Volume: 32, Issue:6

    Topics: Animals; Blotting, Western; Calcineurin; Calcium; Cell Differentiation; Cell Line; Cytosol; Exenatide; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose; Hypoglycemic Agents; Insulin; Insulin Resistance; Mice; Muscle Fibers, Skeletal; Myoblasts; Myosin Heavy Chains; Peptide Fragments; Peptides; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein Isoforms; Receptors, Glucagon; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trans-Activators; Transcription Factors; Venoms

2011
Liver enzymes are associated with hepatic insulin resistance, insulin secretion, and glucagon concentration in healthy men and women.
    Diabetes, 2011, Volume: 60, Issue:6

    Topics: Alanine Transaminase; Diabetes Mellitus, Type 2; Female; gamma-Glutamyltransferase; Glucagon; Humans; Insulin; Insulin Resistance; Insulin Secretion; Liver; Male

2011
Serum prolactin concentrations determine whether they improve or impair β-cell function and insulin sensitivity in diabetic rats.
    Diabetes/metabolism research and reviews, 2011, Volume: 27, Issue:6

    Topics: Adiponectin; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Glucose Clamp Technique; Glucose Tolerance Test; Hydrocortisone; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Pancreatectomy; Prolactin; Rats; Rats, Sprague-Dawley; Testosterone

2011
Effects of biotin deficiency on pancreatic islet morphology, insulin sensitivity and glucose homeostasis.
    The Journal of nutritional biochemistry, 2012, Volume: 23, Issue:4

    Topics: Animals; Biotin; Blood Glucose; Body Weight; Glucagon; Glucose Tolerance Test; Homeostasis; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred BALB C

2012
Olanzapine effects on body composition, food preference, glucose metabolism and insulin sensitivity in the rat.
    Archives of physiology and biochemistry, 2011, Volume: 117, Issue:4

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Body Composition; Body Weight; Diet, High-Fat; Food Preferences; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Liver; Male; Obesity; Olanzapine; Rats; Schizophrenia; Weight Gain

2011
Circulating glucagon is associated with inflammatory mediators in metabolically compromised subjects.
    European journal of endocrinology, 2011, Volume: 165, Issue:4

    Topics: Adult; Aged; Anthropometry; Body Mass Index; Cohort Studies; Complement Factor B; Cross-Sectional Studies; Enzyme-Linked Immunosorbent Assay; Female; Glucagon; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Inflammation Mediators; Insulin Resistance; Interleukin-6; Lipid Metabolism; Male; Metabolic Diseases; Middle Aged; Obesity; Triglycerides; Weight Loss

2011
Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1.
    Diabetologia, 2011, Volume: 54, Issue:11

    Topics: Adolescent; Adult; Age of Onset; Aged; Case-Control Studies; Child; Child, Preschool; Czechoslovakia; Denmark; Diabetes Mellitus, Type 2; Europe; Female; Genetic Association Studies; Glucagon; Glucagon-Like Peptide 1; Homozygote; Humans; Infant; Insulin; Insulin Resistance; Insulin Secretion; Male; Middle Aged; Obesity; Polymorphism, Single Nucleotide

2011
Glucotoxicity and α cell dysfunction: involvement of the PI3K/Akt pathway in glucose-induced insulin resistance in rat islets and clonal αTC1-6 cells.
    Endocrine research, 2012, Volume: 37, Issue:1

    Topics: Animals; Cells, Cultured; Glucagon; Glucagon-Secreting Cells; Glucose; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction

2012
Glucagon and a glucagon-GLP-1 dual-agonist increases cardiac performance with different metabolic effects in insulin-resistant hearts.
    British journal of pharmacology, 2012, Volume: 165, Issue:8

    Topics: Adenosine Triphosphate; Animals; Blood Pressure; Cardiotonic Agents; Glucagon; Glucagon-Like Peptide 1; Glucose; Glycolysis; Heart; Heart Rate; HEK293 Cells; Humans; Insulin Resistance; Male; Oxidation-Reduction; Palmitates; Peptides; Rats

2012
Normalizing action of exendin-4 and GLP-1 in the glucose metabolism of extrapancreatic tissues in insulin-resistant and type 2 diabetic states.
    Journal of molecular endocrinology, 2012, Volume: 48, Issue:1

    Topics: Adipose Tissue; Animals; Biological Transport; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Transporter Type 2; Glucose Transporter Type 4; Glycogen Synthase; Insulin Resistance; Liver; Male; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Peptides; Phosphatidylinositol 3-Kinases; Rats; Rats, Wistar; Venoms

2012
Effect of transjugular intrahepatic portosystemic shunt on glycometabolism in cirrhosis patients.
    Clinics and research in hepatology and gastroenterology, 2012, Volume: 36, Issue:1

    Topics: Adult; Aged; Algorithms; Cardiac Output; Case-Control Studies; Diabetes Mellitus; Female; Glucagon; Glucose Tolerance Test; Hormones; Humans; Hyperinsulinism; Hypertension, Portal; Insulin Resistance; Liver Cirrhosis; Male; Middle Aged; Portasystemic Shunt, Transjugular Intrahepatic; Postoperative Care; Prediabetic State; Predictive Value of Tests; Preoperative Care; Sensitivity and Specificity; Treatment Outcome

2012
Hepatic TRAF2 regulates glucose metabolism through enhancing glucagon responses.
    Diabetes, 2012, Volume: 61, Issue:3

    Topics: Animals; Glucagon; Gluconeogenesis; Glucose; Hepatocytes; Insulin Resistance; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; TNF Receptor-Associated Factor 2

2012
Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice.
    The Journal of clinical investigation, 2012, Volume: 122, Issue:3

    Topics: Animals; Arcuate Nucleus of Hypothalamus; Body Weight; Energy Metabolism; Female; Glucagon; Glucose; Homeostasis; Homozygote; Hypothalamus; Insulin; Insulin Resistance; Leptin; Male; Mice; Mice, Inbred C57BL; Neurons; Pro-Opiomelanocortin; Receptors, Leptin

2012
Changes in gastrointestinal hormone responses, insulin sensitivity, and beta-cell function within 2 weeks after gastric bypass in non-diabetic subjects.
    Obesity surgery, 2012, Volume: 22, Issue:7

    Topics: Adult; Appetite; C-Peptide; Cholecystokinin; Confounding Factors, Epidemiologic; Female; Gastric Bypass; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Hormones; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Islet Amyloid Polypeptide; Leptin; Male; Middle Aged; Obesity, Morbid; Pancreatic Polypeptide; Peptide YY; Postprandial Period; Somatostatin; Time Factors; Weight Loss

2012
Melatonin can improve insulin resistance and aging-induced pancreas alterations in senescence-accelerated prone male mice (SAMP8).
    Age (Dordrecht, Netherlands), 2013, Volume: 35, Issue:3

    Topics: Aging; Animals; Antioxidants; Follow-Up Studies; Gene Expression Regulation, Developmental; Glucagon; Glucose Transporter Type 2; Insulin; Insulin Resistance; Male; Melatonin; Mice; Oxidative Stress; Pancreas; Real-Time Polymerase Chain Reaction; RNA, Messenger

2013
[Important therapy goal in diabetics. Intercept hypoglycemias!].
    MMW Fortschritte der Medizin, 2012, Feb-23, Volume: 154, Issue:3

    Topics: Aged; Autonomic Nervous System; Awareness; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Epinephrine; Glucagon; Glycated Hemoglobin; Humans; Hydrocortisone; Hypoglycemia; Hypoglycemic Agents; Insulin Resistance; Risk Factors

2012
Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes.
    Nature, 2012, Apr-08, Volume: 485, Issue:7396

    Topics: Animals; Blood Glucose; Calcineurin; Calcium; Calcium Signaling; Cells, Cultured; Cyclic AMP; Diabetes Mellitus; Fasting; Gene Expression Regulation; Glucagon; Gluconeogenesis; HEK293 Cells; Hepatocytes; Humans; Inositol 1,4,5-Trisphosphate Receptors; Insulin Resistance; Liver; Mice; Phosphorylation; Trans-Activators; Transcription Factors

2012
Improved blood glucose disposal and altered insulin secretion patterns in adenosine A(1) receptor knockout mice.
    American journal of physiology. Endocrinology and metabolism, 2012, Jul-15, Volume: 303, Issue:2

    Topics: Animals; Blood Glucose; Diet, High-Fat; Eating; Glucagon; Glucose; Glucose Tolerance Test; Insulin; Insulin Resistance; Insulin Secretion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Adenosine A1; Weight Gain

2012
Serum bile acids and leptin interact with glucose metabolism in patients with liver cirrhosis.
    Clinical nutrition (Edinburgh, Scotland), 2013, Volume: 32, Issue:1

    Topics: Adipose Tissue, White; Adult; Bile Acids and Salts; Female; Glucagon; Glucose; Humans; Hyperglycemia; Insulin Resistance; Intestinal Mucosa; Leptin; Liver; Liver Cirrhosis; Male; Middle Aged; Parenteral Nutrition; Postprandial Period

2013
Major liver resection results in early exacerbation of insulin resistance, and may be a risk factor of developing overt diabetes in the future.
    Surgery today, 2013, Volume: 43, Issue:5

    Topics: Adiponectin; Aged; Blood Glucose; Cohort Studies; Diabetes Mellitus; Disease Progression; Female; Glucagon; Glucose Tolerance Test; Hepatectomy; Homeostasis; Humans; Insulin; Insulin Resistance; Interleukin-6; Liver Neoplasms; Male; Middle Aged; Prospective Studies; Risk; Time Factors; Tumor Necrosis Factor-alpha

2013
Omeprazole improves the anti-obesity and antidiabetic effects of exendin-4 in db/db mice (-4 db/db)*.
    Journal of diabetes, 2013, Volume: 5, Issue:2

    Topics: Animals; Anti-Obesity Agents; Body Weight; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Exenatide; Gastrins; Glucagon; Hypoglycemic Agents; Insulin Resistance; Leptin; Male; Mice; Mice, Inbred Strains; Mice, Obese; Obesity; Omeprazole; Peptides; Venoms

2013
Measurement of glucose homeostasis in vivo: combination of tracers and clamp techniques.
    Methods in molecular biology (Clifton, N.J.), 2012, Volume: 933

    Topics: Animals; Blood Glucose; Catheterization; Catheters, Indwelling; Equipment Design; Glucagon; Glucose; Glucose Clamp Technique; Glycogen; Homeostasis; Insulin; Insulin Resistance; Mice; Pancreas; Rats; Vascular Surgical Procedures

2012
In vivo hyperpolarized carbon-13 magnetic resonance spectroscopy reveals increased pyruvate carboxylase flux in an insulin-resistant mouse model.
    Hepatology (Baltimore, Md.), 2013, Volume: 57, Issue:2

    Topics: Animals; Aspartic Acid; Carbon Isotopes; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Glucagon; Gluconeogenesis; Insulin Resistance; Liver; Magnetic Resonance Spectroscopy; Malates; Male; Mice; Mice, Inbred C57BL; Pyruvate Carboxylase; Pyruvic Acid

2013
Direct control of brown adipose tissue thermogenesis by central nervous system glucagon-like peptide-1 receptor signaling.
    Diabetes, 2012, Volume: 61, Issue:11

    Topics: Adipose Tissue, Brown; Animals; Central Nervous System; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Insulin Resistance; Ion Channels; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Proteins; Nerve Tissue Proteins; Neurons; Oxyntomodulin; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Receptors, Glucagon; Scapula; Signal Transduction; Sympathetic Nervous System; Thermogenesis; Trans-Activators; Transcription Factors; Uncoupling Protein 1; Up-Regulation

2012
Moderate alcohol consumption is associated with improved insulin sensitivity, reduced basal insulin secretion rate and lower fasting glucagon concentration in healthy women.
    Diabetologia, 2012, Volume: 55, Issue:12

    Topics: Adult; Alcohol Drinking; Blood Pressure; Fasting; Female; Glucagon; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Middle Aged; Surveys and Questionnaires; Women's Health

2012
Kinetic modeling of human hepatic glucose metabolism in type 2 diabetes mellitus predicts higher risk of hypoglycemic events in rigorous insulin therapy.
    The Journal of biological chemistry, 2012, Oct-26, Volume: 287, Issue:44

    Topics: Algorithms; Blood Glucose; Carbohydrate Metabolism; Computer Simulation; Diabetes Mellitus, Type 2; Epinephrine; Glucagon; Glucose; Glycogen; Hepatocytes; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Kinetics; Liver; Models, Biological; Phosphorylation; Postprandial Period; Protein Processing, Post-Translational

2012
Chronic activation of cannabinoid receptors in vitro does not compromise mouse islet function.
    Clinical science (London, England : 1979), 2013, Volume: 124, Issue:7

    Topics: Animals; Cannabinoid Receptor Agonists; Glucagon; Indoles; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Mice; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2

2013
Chemical cholecystokinin receptor activation protects against obesity-diabetes in high fat fed mice and has sustainable beneficial effects in genetic ob/ob mice.
    Biochemical pharmacology, 2013, Jan-01, Volume: 85, Issue:1

    Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dietary Fats; Eating; Glucagon; Glucose Tolerance Test; Insulin; Insulin Resistance; Lipids; Mice; Mice, Obese; Obesity; Pancreas; Receptors, Cholecystokinin; Sincalide

2013
Homeostasis model assessment of insulin resistance for evaluating insulin sensitivity in patients with type 2 diabetes on insulin therapy.
    Endocrine journal, 2013, Volume: 60, Issue:3

    Topics: Adiponectin; Age Factors; Aged; Blood Pressure; Body Mass Index; C-Reactive Protein; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Clamp Technique; Homeostasis; Humans; Insulin; Insulin Resistance; Intra-Abdominal Fat; Male; Middle Aged; Models, Biological; Reproducibility of Results; Triglycerides; Waist Circumference

2013
Liver-specific disruption of the murine glucagon receptor produces α-cell hyperplasia: evidence for a circulating α-cell growth factor.
    Diabetes, 2013, Volume: 62, Issue:4

    Topics: Animals; Blood Glucose; Female; Glucagon; Glucagon-Secreting Cells; Glucose; Hepatocytes; Hyperplasia; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Islets of Langerhans; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Glucagon; Signal Transduction

2013
Sex differences in insulin resistance in GABAB1 knockout mice.
    Life sciences, 2013, Feb-27, Volume: 92, Issue:3

    Topics: Animals; Eating; Female; Gene Expression Regulation; Glucagon; Hypothalamus; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Insulin Secretion; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Muscle, Skeletal; Neuropeptide Y; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Receptors, GABA-B; Sex Characteristics

2013
Choline supplementation promotes hepatic insulin resistance in phosphatidylethanolamine N-methyltransferase-deficient mice via increased glucagon action.
    The Journal of biological chemistry, 2013, Jan-11, Volume: 288, Issue:2

    Topics: Animals; Base Sequence; Choline; DNA Primers; Glucagon; Gluconeogenesis; Glucose Tolerance Test; Insulin Resistance; Liver; Mice; Mice, Inbred C57BL; Phosphatidylethanolamine N-Methyltransferase

2013
A preliminary investigation of the mechanisms underlying the effect of berberine in preventing high-fat diet-induced insulin resistance in rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2012, Volume: 63, Issue:5

    Topics: Animals; Berberine; Cells, Cultured; Diet, High-Fat; Fatty Acids, Nonesterified; Glucagon; Glucagon-Secreting Cells; Glucose Tolerance Test; Hepatocytes; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Insulin-Secreting Cells; Male; Rats; Rats, Wistar; Receptor, Insulin; Triglycerides

2012
Increased amino acid supply potentiates glucose-stimulated insulin secretion but does not increase β-cell mass in fetal sheep.
    American journal of physiology. Endocrinology and metabolism, 2013, Feb-15, Volume: 304, Issue:4

    Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Animals, Inbred Strains; Arginine; Electrolytes; Female; Fetal Weight; Glucagon; Glucagon-Secreting Cells; Glucose; Infusions, Intravenous; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Organ Size; Pancreas; Pregnancy; Random Allocation; Sheep, Domestic; Solutions

2013
Insulin sensitively controls the glucagon response to mild hypoglycemia in the dog.
    Diabetes, 2002, Volume: 51, Issue:10

    Topics: Alanine; Animals; Blood Glucose; Consciousness; Dihydropyridines; Dogs; Fasting; Fatty Acids, Nonesterified; Female; Furans; Glucagon; Gluconeogenesis; Glycerol; Glycogen; Hypoglycemia; Insulin; Insulin Resistance; Islets of Langerhans; Ketones; Lactic Acid; Liver; Liver Circulation; Male

2002
Reduction of hepatic glycogen synthesis and breakdown in patients with agenesis of the dorsal pancreas.
    The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:10

    Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Gluconeogenesis; Glucose Tolerance Test; Glycogen; Human Growth Hormone; Humans; Hydrocortisone; Insulin; Insulin Resistance; Insulin Secretion; Kinetics; Leptin; Liver; Magnetic Resonance Spectroscopy; Male; Middle Aged; Norepinephrine; Pancreas

2002
Elevated glucagon-like peptide-1-(7-36)-amide, but not glucose, associated with hyperinsulinemic compensation for fat feeding.
    The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:11

    Topics: Animals; Blood Glucose; Blotting, Northern; Dietary Fats; Dogs; Fasting; Fatty Acids, Nonesterified; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Hyperinsulinism; Insulin; Insulin Resistance; Islets of Langerhans; Kinetics; Magnetic Resonance Imaging; Male; Obesity; Peptide Fragments; Receptors, Glucagon; Reverse Transcriptase Polymerase Chain Reaction

2002
An inadequate glycaemic response to glucagon is linked to insulin resistance in preterm infants?
    Archives of disease in childhood. Fetal and neonatal edition, 2003, Volume: 88, Issue:1

    Topics: Blood Glucose; Fasting; Glucagon; Humans; Infant, Newborn; Infant, Premature; Injections, Intravenous; Insulin; Insulin Resistance; Predictive Value of Tests

2003
Combined pancreas and kidney transplantation in a lean type 2 diabetic patient. Effects on insulin secretion and sensitivity.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2002, Volume: 110, Issue:8

    Topics: Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Glucagon; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Kidney Function Tests; Kidney Transplantation; Middle Aged; Pancreas Transplantation

2002
Residual C-peptide secretion and endothelial function in patients with Type II diabetes.
    Clinical science (London, England : 1979), 2003, Volume: 105, Issue:1

    Topics: Aged; Analysis of Variance; Area Under Curve; Brachial Artery; C-Peptide; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Glucagon; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Nitroglycerin; Oxidative Stress; Regional Blood Flow; Thiobarbituric Acid Reactive Substances; Ultrasonography; Vasodilator Agents

2003
Mechanisms for the deterioration in glucose tolerance associated with HIV protease inhibitor regimens.
    Diabetes, 2003, Volume: 52, Issue:4

    Topics: Adipose Tissue; Adult; Blood Glucose; Body Composition; Body Constitution; C-Peptide; CD4 Lymphocyte Count; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Clamp Technique; Glucose Intolerance; Glycated Hemoglobin; Glycerol; HIV Infections; HIV Protease Inhibitors; Homeostasis; Humans; Insulin; Insulin Resistance; Islets of Langerhans; Lipids; Liver; Male; Middle Aged; Muscle, Skeletal; Proinsulin; Viral Load

2003
PTG gene deletion causes impaired glycogen synthesis and developmental insulin resistance.
    The Journal of clinical investigation, 2003, Volume: 111, Issue:9

    Topics: Aging; Animals; Carrier Proteins; Female; Gene Deletion; Glucagon; Glucose; Glycogen; Glycogen Synthase; Homeostasis; Humans; Insulin; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Liver; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Phosphoprotein Phosphatases; Signal Transduction; Triglycerides

2003
Metabolic adaptations to dexamethasone-induced insulin resistance in healthy volunteers.
    Obesity research, 2003, Volume: 11, Issue:5

    Topics: Adult; Blood Glucose; Dexamethasone; Fatty Acids, Nonesterified; Female; Glucagon; Glucocorticoids; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Triglycerides

2003
Interferon-alpha reduces insulin resistance and beta-cell secretion in responders among patients with chronic hepatitis B and C.
    The Journal of endocrinology, 2003, Volume: 178, Issue:3

    Topics: Adult; Alanine Transaminase; Analysis of Variance; Autoantibodies; Blood Glucose; C-Peptide; Chi-Square Distribution; Diabetes Mellitus, Type 1; DNA, Viral; Female; Glucagon; Glucose Tolerance Test; Hepatitis B e Antigens; Hepatitis B, Chronic; Hepatitis C, Chronic; Homeostasis; Humans; Insulin; Insulin Resistance; Insulin Secretion; Interferon-alpha; Islets of Langerhans; Male; Middle Aged

2003
Studies with glucagon in patients with insulin sensitivity.
    Journal of the American Medical Association, 1955, Nov-12, Volume: 159, Issue:11

    Topics: Blood Glucose; Diabetes Mellitus; Glucagon; Hormones; Humans; Insulin; Insulin Resistance; Pancreas; Pancreatic Hormones

1955
Influence of adrenal extirpation, adrenal cortex hormones and glucagon on the insulin-sensitivity of eviscerated rats
    Acta endocrinologica, 1962, Volume: 39

    Topics: Adrenal Cortex Hormones; Adrenalectomy; Animals; Glucagon; Insulin; Insulin Resistance; Rats

1962
[CLINICAL SIGNIFICANCE OF INSULIN RESISTANCE].
    Polskie Archiwum Medycyny Wewnetrznej, 1964, Volume: 34

    Topics: Acidosis; Acromegaly; Adrenal Gland Diseases; Drug Hypersensitivity; Endopeptidases; Glucagon; Humans; Hyperthyroidism; Insulin; Insulin Antibodies; Insulin Resistance; Peptide Hydrolases; Surgical Procedures, Operative; Toxicology; Trypsin

1964
LIPOATROPHIC DIABETES. I. STUDIES CONCERNING ENDOCRINE FUNCTION AND CARBOHYDRATE METABOLISM.
    American journal of diseases of children (1960), 1965, Volume: 109

    Topics: Adolescent; Carbohydrate Metabolism; Diabetes Mellitus, Lipoatrophic; Diabetes Mellitus, Type 1; Drug Tolerance; Epinephrine; Fatty Acids; Glucagon; Glucose Tolerance Test; Hepatomegaly; Humans; Infant; Insulin; Insulin Resistance; L-Lactate Dehydrogenase; Leucine; Lipids; Lipodystrophy; Liver; Liver Cirrhosis; Liver Function Tests; Metyrapone; Pharmacology; Pituitary-Adrenal Function Tests; Radiography; Tolbutamide; Transaminases; Urine

1965
[THE EFFECT OF GLUCAGON IN PATIENTS WITH INSULIN RESISTANCE OR INSULIN ALLERGY].
    Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1965, Volume: 46

    Topics: Diabetes Mellitus; Drug Hypersensitivity; Geriatrics; Glucagon; Humans; Insulin; Insulin Resistance; Pharmacology; Skin Tests; Toxicology

1965
Impaired glucose homeostasis in mice lacking the alpha1b-adrenergic receptor subtype.
    The Journal of biological chemistry, 2004, Jan-09, Volume: 279, Issue:2

    Topics: Animals; Blood Glucose; Body Weight; Glucagon; Glucose; Glycogen; Homeostasis; Hyperinsulinism; Insulin Resistance; Leptin; Liver; Male; Mice; Mice, Mutant Strains; Mice, Obese; Receptors, Adrenergic; Receptors, Adrenergic, alpha-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors

2004
Insulin-independent effects of GLP-1 on canine liver glucose metabolism: duration of infusion and involvement of hepatoportal region.
    American journal of physiology. Endocrinology and metabolism, 2004, Volume: 287, Issue:1

    Topics: Animals; Blood Glucose; Dogs; Dose-Response Relationship, Drug; Female; Glucagon; Glucagon-Like Peptide 1; Glucose; Infusions, Intravenous; Insulin; Insulin Resistance; Liver; Male; Metabolic Clearance Rate; Peptide Fragments; Portal System; Protein Precursors

2004
Loss-of-function mutation of the galanin gene is associated with perturbed islet function in mice.
    Endocrinology, 2004, Volume: 145, Issue:7

    Topics: Animals; Antimetabolites; Body Weight; Deoxyglucose; Galanin; Glucagon; Glucose; Glucose Clamp Technique; Hyperinsulinism; Hypoglycemic Agents; Immunohistochemistry; Insulin; Insulin Resistance; Islets of Langerhans; Mice; Mice, Inbred Strains; Mice, Knockout; Sympathetic Nervous System

2004
Elevated fasting plasma ghrelin in prader-willi syndrome adults is not solely explained by their reduced visceral adiposity and insulin resistance.
    The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:4

    Topics: Adipose Tissue; Adult; Case-Control Studies; Fasting; Female; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin Resistance; Male; Middle Aged; Peptide Fragments; Peptide Hormones; Prader-Willi Syndrome; Protein Precursors; Regression Analysis; Viscera

2004
Insulin secretion and incretin hormones after oral glucose in non-obese subjects with impaired glucose tolerance.
    Metabolism: clinical and experimental, 2004, Volume: 53, Issue:5

    Topics: Administration, Oral; Area Under Curve; Blood Glucose; Body Weight; C-Peptide; Case-Control Studies; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Liver; Middle Aged; Peptide Fragments; Protein Precursors; Regression Analysis; Time Factors

2004
Modulation of basal glucose metabolism and insulin sensitivity by growth hormone and free fatty acids during short-term fasting.
    European journal of endocrinology, 2004, Volume: 150, Issue:6

    Topics: Adult; Amino Acids; Blood Flow Velocity; Blood Glucose; Calorimetry, Indirect; Fasting; Fatty Acids, Nonesterified; Forearm; Glucagon; Glucose Clamp Technique; Glycerol; Human Growth Hormone; Humans; Insulin; Insulin Resistance; Lactic Acid; Lipolysis; Male; Microdialysis; Plethysmography; Pyrazines; Somatostatin

2004
Recombinant glucagon-like peptide-1 increases myocardial glucose uptake and improves left ventricular performance in conscious dogs with pacing-induced dilated cardiomyopathy.
    Circulation, 2004, Aug-24, Volume: 110, Issue:8

    Topics: Animals; Blood Glucose; Cardiac Pacing, Artificial; Cardiomyopathy, Dilated; Consciousness; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Energy Metabolism; Fatty Acids; Female; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Clamp Technique; Heart Failure; Hemodynamics; Hyperinsulinism; Infusions, Intravenous; Insulin Resistance; Male; Myocardium; Oxygen Consumption; Peptide Fragments; Protein Precursors; Recombinant Proteins; Ventricular Dysfunction, Left

2004
Cardiac metabolism as a target for the treatment of heart failure.
    Circulation, 2004, Aug-24, Volume: 110, Issue:8

    Topics: Acetanilides; Animals; Dogs; Energy Metabolism; Epoxy Compounds; Fatty Acids; Forecasting; Glucagon; Glucagon-Like Peptide 1; Glucose; Heart Failure; Humans; Insulin Resistance; Myocardium; Peptide Fragments; Piperazines; Protein Precursors; Ranolazine; Recombinant Proteins

2004
Beta-cell dysfunction in classic transient neonatal diabetes is characterized by impaired insulin response to glucose but normal response to glucagon.
    Diabetes care, 2004, Volume: 27, Issue:10

    Topics: Chromosome Aberrations; Chromosomes, Human, Pair 6; Diabetes Mellitus; Female; Glucagon; Glucose Tolerance Test; Humans; Infant, Newborn; Insulin; Insulin Resistance; Islets of Langerhans; Male; Pedigree; Rare Diseases; Remission, Spontaneous; Risk Assessment; Sampling Studies; Siblings

2004
Characterization of beta-cell function impairment in first-degree relatives of type 2 diabetic subjects: modeling analysis of 24-h triple-meal tests.
    American journal of physiology. Endocrinology and metabolism, 2005, Volume: 288, Issue:3

    Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Diet; Energy Intake; Family; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Clamp Technique; Glucose Intolerance; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Linear Models; Male; Models, Biological; Multivariate Analysis; Peptide Fragments; Protein Precursors

2005
Insulin resistance and abomasal motility disorders in cows detected by use of abomasoduodenal electromyography after surgical correction of left displaced abomasum.
    American journal of veterinary research, 2004, Volume: 65, Issue:10

    Topics: 3-Hydroxybutyric Acid; Abomasum; Animals; Blood Glucose; Cattle; Cattle Diseases; Electromyography; Fatty Acids, Nonesterified; Female; Gastrointestinal Motility; Glucagon; Hydrocortisone; Insulin; Insulin Resistance; Stomach Diseases

2004
[The role of incretins. Type 2 diabetes with new beginnings].
    MMW Fortschritte der Medizin, 2005, Mar-10, Volume: 147, Issue:10

    Topics: Diabetes Mellitus, Type 2; Disease Progression; Exenatide; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Peptide Fragments; Peptides; Protein Precursors; Venoms

2005
Increased glucose tolerance in N-type Ca2+ channel alpha(1B)-subunit gene-deficient mice.
    International journal of molecular medicine, 2005, Volume: 15, Issue:6

    Topics: Animals; Blood Glucose; Body Weight; Calcium Channels, N-Type; Crosses, Genetic; Dietary Fats; Eating; Fasting; Glucagon; Glucose; Glucose Tolerance Test; Heterozygote; Homeostasis; Homozygote; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Obesity; Polymerase Chain Reaction; Protein Subunits

2005
Diabetogenic effects and pancreatic oxidative damage in rats subchronically exposed to arsenite.
    Toxicology letters, 2006, Jan-05, Volume: 160, Issue:2

    Topics: Animals; Arsenites; Blood Glucose; Enzyme Inhibitors; Glucagon; Glutathione; Immunohistochemistry; Insulin Resistance; Lipid Peroxidation; Male; Models, Animal; Oxidative Stress; Pancreas; Rats; Rats, Wistar; Sodium Compounds; Thioredoxin-Disulfide Reductase

2006
Hepatic insulin gene therapy prevents deterioration of vascular function and improves adipocytokine profile in STZ-diabetic rats.
    American journal of physiology. Endocrinology and metabolism, 2006, Volume: 290, Issue:1

    Topics: Acetylcholine; Adenoviridae; Adiponectin; Animals; Aorta; Blood Glucose; Body Weight; Cardiovascular Physiological Phenomena; Diabetes Mellitus, Experimental; Erythrocytes; Genetic Therapy; Glucagon; Hemoglobins; Humans; In Vitro Techniques; Injections, Intravenous; Insulin; Insulin Resistance; Leptin; Lipids; Liver; Male; Nitric Oxide Synthase; Nitroprusside; Peptide Hormones; Rats; Rats, Sprague-Dawley; Vasodilation

2006
FK-614, a selective peroxisome proliferator-activated receptor gamma agonist, improves peripheral glucose utilization while decreasing hepatic insulin extraction in alloxan-induced diabetic dogs.
    Metabolism: clinical and experimental, 2005, Volume: 54, Issue:9

    Topics: Animals; Benzimidazoles; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Dogs; Fatty Acids, Nonesterified; Glucagon; Glucose; Glucose Clamp Technique; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin, Isophane; Liver; Male; PPAR gamma; Tritium

2005
[Novel therapy in type 2 diabetes: to regulate glucose metabolism naturally].
    MMW Fortschritte der Medizin, 2005, Aug-04, Volume: 147, Issue:31-32

    Topics: Animals; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucose; Humans; Hypoglycemic Agents; Infant, Newborn; Insulin Resistance; Lizards; Peptide Fragments; Peptides; Protein Precursors; Time Factors; Venoms

2005
VGF ablation blocks the development of hyperinsulinemia and hyperglycemia in several mouse models of obesity.
    Endocrinology, 2005, Volume: 146, Issue:12

    Topics: Adipose Tissue; Animals; Diet; Disease Models, Animal; Disease Susceptibility; Energy Intake; Glucagon; Glucose; Homeostasis; Hyperglycemia; Hyperinsulinism; Hypoglycemia; Injections, Intraperitoneal; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Growth Factors; Neuropeptides; Obesity; Proteins; Receptor, Melanocortin, Type 4

2005
Insulin sensitivity and counter-regulatory hormones in hypothyroidism and during thyroid hormone replacement therapy.
    Clinical chemistry and laboratory medicine, 2005, Volume: 43, Issue:7

    Topics: Adult; Blood Glucose; C-Peptide; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Hormones; Human Growth Hormone; Humans; Hydrocortisone; Hypothyroidism; Insulin; Insulin Resistance; Insulin Secretion; Thyroid Hormones

2005
Human duodenal enteroendocrine cells: source of both incretin peptides, GLP-1 and GIP.
    American journal of physiology. Endocrinology and metabolism, 2006, Volume: 290, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Area Under Curve; Biopsy; Diabetes Mellitus, Type 2; Duodenum; Enteroendocrine Cells; Enzyme-Linked Immunosorbent Assay; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Humans; Immunohistochemistry; Insulin; Insulin Resistance; Male; Middle Aged; Peptide Fragments; Reverse Transcriptase Polymerase Chain Reaction

2006
Increased glucose tolerance and reduced adiposity in the absence of fasting hypoglycemia in mice with liver-specific Gs alpha deficiency.
    The Journal of clinical investigation, 2005, Volume: 115, Issue:11

    Topics: Adiposity; Animals; Eating; Fasting; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Tolerance Test; GTP-Binding Protein alpha Subunits, Gs; Hypoglycemia; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Lipid Metabolism; Liver; Male; Mice; Mice, Knockout; Mice, Transgenic; Oxygen Consumption; Signal Transduction

2005
[A study on the mechanism of islet cell insulin resistance in high-fat-diet obese rats].
    Zhonghua yi xue za zhi, 2005, Jul-20, Volume: 85, Issue:27

    Topics: Animals; Diet, High-Fat; Glucagon; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Obesity; Rats; Rats, Wistar; Receptor, Insulin; Signal Transduction

2005
Reduced intrahepatic fat content is associated with increased whole-body lipid oxidation in patients with type 1 diabetes.
    Diabetologia, 2005, Volume: 48, Issue:12

    Topics: Adiponectin; Adult; Anthropometry; Blood Glucose; Calorimetry, Indirect; Case-Control Studies; Diabetes Mellitus, Type 1; Energy Metabolism; Female; Glucagon; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Lipid Metabolism; Lipids; Liver; Magnetic Resonance Spectroscopy; Male; Oxidation-Reduction

2005
Insulin resistance causes increased beta-cell mass but defective glucose-stimulated insulin secretion in a murine model of type 2 diabetes.
    Diabetologia, 2006, Volume: 49, Issue:1

    Topics: Animals; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Type 2; Dietary Sucrose; Disease Models, Animal; Glucagon; Glucose; Homeostasis; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Mice; Mice, Inbred Strains; Receptor, Insulin

2006
Intra-islet insulin suppresses glucagon release via GABA-GABAA receptor system.
    Cell metabolism, 2006, Volume: 3, Issue:1

    Topics: Animals; Female; GABA-A Receptor Antagonists; Glucagon; Glucagon-Secreting Cells; Guinea Pigs; Humans; Insulin; Insulin Resistance; Islets of Langerhans; Male; Models, Biological; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

2006
Taiwanese vegetarians have higher insulin sensitivity than omnivores.
    The British journal of nutrition, 2006, Volume: 95, Issue:1

    Topics: Adult; Blood Glucose; Body Mass Index; Body Size; Diet, Vegetarian; Energy Intake; Feeding Behavior; Female; Glucagon; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Middle Aged; Taiwan

2006
Glucose-stimulated prehepatic insulin secretion is associated with circulating alanine, triglyceride, glucagon, lactate and TNF-alpha in patients with HIV-lipodystrophy.
    HIV medicine, 2006, Volume: 7, Issue:3

    Topics: Adult; Alanine; C-Peptide; Case-Control Studies; Glucagon; Glucose; Glucose Clamp Technique; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Infusions, Intravenous; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Lactates; Male; Middle Aged; Stimulation, Chemical; Triglycerides; Tumor Necrosis Factor-alpha

2006
Sexual dimorphism in insulin sensitivity and susceptibility to develop diabetes in rats.
    The Journal of endocrinology, 2006, Volume: 190, Issue:2

    Topics: Animals; Biomarkers; Blood Glucose; Body Composition; Diabetes Mellitus, Experimental; Disease Susceptibility; Female; Glucagon; Glucose Tolerance Test; Immunohistochemistry; Insulin; Insulin Resistance; Islets of Langerhans; Male; Microscopy, Confocal; Niacinamide; Rats; Rats, Wistar; Sex Characteristics

2006
Distinct endocrine effects of chronic haloperidol or risperidone administration in male rats.
    Neuropharmacology, 2006, Volume: 51, Issue:7-8

    Topics: Adipose Tissue; Animals; Antipsychotic Agents; Appetite; Body Weight; Corticosterone; Diabetes Mellitus, Type 2; Endocrine System; Energy Intake; Glucagon; Haloperidol; Hyperinsulinism; Insulin; Insulin Resistance; Insulin Secretion; Lipid Metabolism; Male; Obesity; Rats; Rats, Sprague-Dawley; Risperidone; Species Specificity; Testosterone; Weight Gain

2006
[Study of relationship between stress hyperglycemia and insulin-resistance related factors].
    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2006, Volume: 18, Issue:12

    Topics: Adult; Aged; C-Peptide; Critical Illness; Female; Glucagon; Humans; Hydrocortisone; Hyperglycemia; Insulin; Insulin Resistance; Intensive Care Units; Male; Middle Aged; Stress, Physiological; Tumor Necrosis Factor-alpha; Young Adult

2006
Restructuring of pancreatic islets and insulin secretion in a postnatal critical window.
    PloS one, 2006, Dec-20, Volume: 1

    Topics: Age Factors; Animals; Blood Glucose; Cell Aggregation; Cell Count; Cells, Cultured; Diet; Glucagon; Glucagon-Secreting Cells; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Male; Rats; Rats, Wistar; Weaning

2006
[The expression of insulin signal transduction molecules and islet alpha cell insulin resistance].
    Zhonghua yi xue za zhi, 2006, Sep-26, Volume: 86, Issue:36

    Topics: Adaptor Proteins, Signal Transducing; Animals; Blood Glucose; Fatty Acids, Nonesterified; Gene Expression; Glucagon; Glucose Clamp Technique; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Islets of Langerhans; Male; Phosphatidylinositol 3-Kinases; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Triglycerides

2006
Awareness of pathophysiological concepts of type 2 diabetes: a survey in 847 physicians.
    Diabetes research and clinical practice, 2007, Volume: 76, Issue:3

    Topics: Clinical Competence; Diabetes Mellitus, Type 2; Family Practice; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Glucose; Humans; Insulin Resistance; Insulin-Secreting Cells; Liver; Online Systems; Primary Health Care; Surveys and Questionnaires

2007
Contribution of hepatic and extrahepatic insulin resistance to the pathogenesis of impaired fasting glucose: role of increased rates of gluconeogenesis.
    Diabetes, 2007, Volume: 56, Issue:6

    Topics: Adipose Tissue; Blood Glucose; Body Mass Index; C-Peptide; Fasting; Female; Glucagon; Gluconeogenesis; Glucose Intolerance; Humans; Hyperglycemia; Insulin Resistance; Liver; Male; Middle Aged; Reference Values

2007
Glucagon as a determinant of fibrinolytic activity in men with different stages of glucose tolerance: impact of glucagon on fibrinolysis.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2007, Volume: 18, Issue:4

    Topics: Aged; Area Under Curve; Diabetes Mellitus, Type 2; Fibrinolysis; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin Resistance; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Tissue Plasminogen Activator

2007
Glucagon receptor antagonism improves islet function in mice with insulin resistance induced by a high-fat diet.
    Diabetologia, 2007, Volume: 50, Issue:7

    Topics: Animal Feed; Animals; Blood Glucose; Diet; Female; Glucagon; Glucose Tolerance Test; Insulin; Insulin Resistance; Islets of Langerhans; Mice; Mice, Inbred C57BL; Oxygen; Receptors, Glucagon; Time Factors

2007
Pancreatic insulin secretion in rats fed a soy protein high fat diet depends on the interaction between the amino acid pattern and isoflavones.
    The Journal of biological chemistry, 2007, Jul-13, Volume: 282, Issue:28

    Topics: Amino Acids; Animals; Blood Glucose; Caseins; Cells, Cultured; Dietary Fats; Dietary Proteins; Gene Expression Regulation; Glucagon; Glucose Clamp Technique; Glucose Transporter Type 2; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Isoflavones; Leptin; Obesity; PPAR gamma; Rats; Rats, Sprague-Dawley; Soybean Proteins; Sterol Regulatory Element Binding Protein 1

2007
The common C49620T polymorphism in the sulfonylurea receptor gene (ABCC8), pancreatic beta cell function and long-term diabetic complications in obese patients with long-lasting type 2 diabetes mellitus.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2007, Volume: 115, Issue:5

    Topics: Aged; ATP-Binding Cassette Transporters; Chronic Disease; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Injections, Intravenous; Insulin Resistance; Insulin-Secreting Cells; Male; Middle Aged; Obesity; Polymorphism, Single Nucleotide; Potassium Channels; Potassium Channels, Inwardly Rectifying; Prevalence; Receptors, Drug; Stroke; Sulfonylurea Receptors; Time Factors

2007
Contributions of glucokinase and phosphofructokinase-2/fructose bisphosphatase-2 to the elevated glycolysis in hepatocytes from Zucker fa/fa rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2007, Volume: 293, Issue:2

    Topics: Animals; Cells, Cultured; Gene Expression Regulation, Enzymologic; Glucagon; Glucokinase; Glucose; Glycolysis; Hepatocytes; Insulin Resistance; Male; Phosphofructokinase-2; Rats; Rats, Zucker; Recombinant Proteins

2007
Chemical gastric inhibitory polypeptide receptor antagonism protects against obesity, insulin resistance, glucose intolerance and associated disturbances in mice fed high-fat and cafeteria diets.
    Diabetologia, 2007, Volume: 50, Issue:8

    Topics: Adiponectin; Animals; Blood Glucose; Body Weight; Corticosterone; Dietary Fats; Eating; Gastric Inhibitory Polypeptide; Glucagon; Glucose Intolerance; Glycated Hemoglobin; Insulin; Insulin Resistance; Lipids; Locomotion; Male; Mice; Mice, Obese; Obesity; Receptors, Gastrointestinal Hormone

2007
Possible role of alpha-cell insulin resistance in exaggerated glucagon responses to arginine in type 2 diabetes.
    Diabetes care, 2007, Volume: 30, Issue:10

    Topics: Adult; Aged; Area Under Curve; Arginine; Body Mass Index; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Insulin Resistance; Insulin-Secreting Cells; Japan; Male; Middle Aged; Reference Values

2007
Susceptibility to oxidative stress, insulin resistance, and insulin secretory response in the development of diabetes from obesity.
    Vojnosanitetski pregled, 2007, Volume: 64, Issue:6

    Topics: Adult; Antioxidants; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Insulin; Insulin Resistance; Insulin Secretion; Lipid Peroxidation; Male; Malondialdehyde; Middle Aged; Obesity; Oxidative Stress

2007
Association of fasting glucagon and proinsulin concentrations with insulin resistance.
    Diabetologia, 2007, Volume: 50, Issue:11

    Topics: Adolescent; Adult; Analysis of Variance; Body Mass Index; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin Resistance; Male; Multivariate Analysis; Proinsulin

2007
GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet.
    American journal of physiology. Endocrinology and metabolism, 2007, Volume: 293, Issue:6

    Topics: Adipokines; Adipose Tissue; Animals; Anti-Obesity Agents; Blood Glucose; Body Weight; Corticosterone; Dietary Fats; Eating; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Incretins; Insulin; Insulin Resistance; Lipids; Liver; Male; Mice; Motor Activity; Muscle, Skeletal; Obesity; Pancreas; Receptors, Gastrointestinal Hormone

2007
Patients with neuroglycopenia after gastric bypass surgery have exaggerated incretin and insulin secretory responses to a mixed meal.
    The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:12

    Topics: Adult; Aged; Blood Glucose; Body Mass Index; C-Peptide; Eating; Female; Food; Gastric Bypass; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Hypoglycemia; Incretins; Insulin; Insulin Resistance; Male; Middle Aged; Obesity; Obesity, Morbid; Postoperative Complications

2007
[The relationship between islet alpha cell insulin resistance and inflammatory pathway activation and its mechanism].
    Zhonghua nei ke za zhi, 2007, Volume: 46, Issue:8

    Topics: Animals; Fatty Acids, Nonesterified; Glucagon; Hypoglycemic Agents; Inflammation; Insulin; Insulin Resistance; Islets of Langerhans; Male; Pioglitazone; Random Allocation; Rats; Rats, Sprague-Dawley; Signal Transduction; Thiazolidinediones

2007
Hepatic insulin resistance in antipsychotic naive schizophrenic patients: stable isotope studies of glucose metabolism.
    The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:2

    Topics: Absorptiometry, Photon; Adult; Blood Glucose; Body Composition; Calorimetry, Indirect; Case-Control Studies; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Glucose Clamp Technique; Humans; Hydrocortisone; Insulin; Insulin Resistance; Liver; Male; Norepinephrine; Oxygen Consumption; Schizophrenia; Statistics, Nonparametric

2008
Independent measures of insulin secretion and insulin sensitivity during the same test: the glucagon-insulin tolerance test.
    Journal of internal medicine, 2008, Volume: 264, Issue:1

    Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Clamp Technique; Glucose Tolerance Test; Hormones; Humans; Insulin; Insulin Resistance; Insulin Secretion; Male; Middle Aged; Reproducibility of Results

2008
Increased pancreatic islet mass is accompanied by activation of the insulin receptor substrate-2/serine-threonine kinase pathway and augmented cyclin D2 protein levels in insulin-resistant rats.
    International journal of experimental pathology, 2008, Volume: 89, Issue:4

    Topics: Animals; Cell Cycle Proteins; Cell Proliferation; Cyclin D2; Cyclins; Dexamethasone; Glucagon; Immunoenzyme Techniques; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Islets of Langerhans; Male; Microscopy, Electron, Transmission; Models, Animal; Phosphoproteins; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Signal Transduction

2008
Diabetes mellitus: customizing management.
    Hospital practice (Office ed.), 1984, Volume: 19, Issue:10

    Topics: Adult; Aging; Biguanides; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Dietary Fats; Dietary Fiber; Female; Glucagon; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Insulin; Insulin Resistance; Male; Monitoring, Physiologic; Pregnancy; Pregnancy in Diabetics; Sulfonylurea Compounds

1984
Evaluation of insulin resistance during inhibition of endogenous insulin and glucagon secretion by somatostatin in non-obese subjects with impaired glucose tolerance.
    Diabetologia, 1981, Volume: 21, Issue:3

    Topics: Adult; Blood Glucose; C-Peptide; Fatty Acids, Nonesterified; Glucagon; Glucose Tolerance Test; Glycerol; Humans; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Male; Reference Values; Somatostatin

1981
[Measurement of insulin sensitivity using the somatostatin-insulin-glucose test. Importance of the determination of plasma free fatty acids and insulin clearance].
    Presse medicale (Paris, France : 1983), 1983, Nov-12, Volume: 12, Issue:40

    Topics: Adult; Aged; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Humans; Insulin; Insulin Resistance; Male; Perfusion; Somatostatin

1983
Insulin and glucagon binding to isolated hepatocytes of Egyptian sand rats (Psammomys obesus): evidence for an insulin receptor defect.
    Comparative biochemistry and physiology. A, Comparative physiology, 1984, Volume: 78, Issue:3

    Topics: Animals; Arvicolinae; Binding Sites; Female; Glucagon; Insulin; Insulin Resistance; Liver; Male; Rats; Rats, Inbred Strains; Receptor, Insulin

1984
The binding of pancreatic hormones to isolated chicken hepatocytes.
    General and comparative endocrinology, 1982, Volume: 46, Issue:3

    Topics: Animals; Cell Separation; Chickens; Glucagon; Insulin; Insulin Resistance; Kinetics; Liver; Male; Pancreatic Hormones; Pancreatic Polypeptide; Receptors, Cell Surface

1982
[Insulin and glucagon receptors in the liver. Their regulation].
    Medecine & chirurgie digestives, 1981, Volume: 10, Issue:8

    Topics: Animals; Binding, Competitive; Cyclic AMP; Glucagon; Humans; Insulin Resistance; Liver; Rats; Rats, Zucker; Receptor, Insulin; Receptors, Cell Surface; Receptors, Glucagon

1981
Glucose intolerance in spinal cord injury.
    Archives of physical medicine and rehabilitation, 1983, Volume: 64, Issue:3

    Topics: Adult; Blood Glucose; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Middle Aged; Spinal Cord Injuries

1983
[The role of insulin-dependent cytoplasmic regulator in carbohydrate metabolism during immobilization].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1983, Volume: 69, Issue:5

    Topics: Animals; Cytoplasm; Diaphragm; Glucagon; Gluconeogenesis; Immobilization; Insulin; Insulin Resistance; Liver; Liver Glycogen; Male; Mitochondria, Liver; Myocardium; Rats; Stress, Physiological

1983
Eucaloric substitution of medium chain triglycerides for dietary long chain fatty acids in acquired total lipodystrophy: effects on hyperlipoproteinemia and endogenous insulin resistance.
    The Journal of clinical endocrinology and metabolism, 1983, Volume: 57, Issue:3

    Topics: Adolescent; Chylomicrons; Dietary Fats; Fatty Acids; Glucagon; Glucose; Humans; Insulin; Insulin Resistance; Lipids; Lipodystrophy; Lipoproteins; Male; Triglycerides; Xanthomatosis

1983
Epinephrine acutely mediates skeletal muscle insulin resistance.
    Surgery, 1983, Volume: 94, Issue:2

    Topics: Adult; Epinephrine; Fatty Acids, Nonesterified; Female; Forearm; Glucagon; Glucose; Humans; Insulin; Insulin Resistance; Lactates; Male; Muscles; Pyruvates

1983
Effect of oral contraceptives on plasma glucose, insulin, and glucagon levels.
    American journal of obstetrics and gynecology, 1983, Nov-15, Volume: 147, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Arginine; Blood Glucose; Contraceptives, Oral, Combined; Drug Combinations; Female; Glucagon; Glucose Tolerance Test; Humans; Infusions, Parenteral; Insulin; Insulin Resistance; Mestranol; Norethindrone

1983
Normal insulin sensitivity of the islets of Langerhans in obese subjects with resistance to its glucoregulatory actions.
    Diabetes, 1984, Volume: 33, Issue:4

    Topics: Adult; Blood Glucose; C-Peptide; Glucagon; Humans; Insulin; Insulin Infusion Systems; Insulin Resistance; Islets of Langerhans; Male; Obesity

1984
Induction of insulin resistance in normal adipose tissue by uremic human serum.
    Kidney international, 1984, Volume: 25, Issue:2

    Topics: Adipose Tissue; Adult; Aged; Animals; Blood Urea Nitrogen; Creatinine; Culture Techniques; Female; Glucagon; Glucose; Growth Hormone; Humans; Hydrocortisone; Insulin; Insulin Resistance; Lipolysis; Male; Middle Aged; Parathyroid Hormone; Rats; Rats, Inbred Strains; Uremia

1984
Insulin resistance in a young man with cystic fibrosis.
    American journal of diseases of children (1960), 1984, Volume: 138, Issue:7

    Topics: Adolescent; Cystic Fibrosis; Gastric Inhibitory Polypeptide; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Male; Obesity; Receptor, Insulin

1984
Hyperinsulinaemia in non-cirrhotic haemochromatosis: impaired hepatic insulin degradation?
    Diabetologia, 1984, Volume: 26, Issue:6

    Topics: Adult; Blood Glucose; C-Peptide; Gastric Inhibitory Polypeptide; Glucagon; Hemochromatosis; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Liver; Male; Middle Aged

1984
Glucose counterregulation and waning of insulin in the Somogyi phenomenon (posthypoglycemic hyperglycemia).
    The New England journal of medicine, 1984, Nov-08, Volume: 311, Issue:19

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Insulin; Insulin Resistance; Male; Norepinephrine

1984
Impaired plasma amino-acid clearance in patients with cirrhosis of the liver and portocaval shunt--its relation to insulin resistance.
    European journal of clinical investigation, 1984, Volume: 14, Issue:4

    Topics: 3-Hydroxybutyric Acid; Adult; Amino Acids; Blood Glucose; C-Peptide; Catecholamines; Fatty Acids, Nonesterified; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hydroxybutyrates; Insulin; Insulin Resistance; Liver Cirrhosis; Male; Middle Aged; Portacaval Shunt, Surgical; Reference Values

1984
Glucoregulation in obese man: effects of fasting, glucagon infusion, exercise and diabetes.
    International journal of obesity, 1982, Volume: 6 Suppl 1

    Topics: Diabetes Mellitus; Fasting; Glucagon; Glucose; Humans; Insulin; Insulin Resistance; Obesity; Physical Exertion

1982
Insulin resistance and decreased insulin response to glucose in lean type 2 diabetics.
    Proceedings of the National Academy of Sciences of the United States of America, 1982, Volume: 79, Issue:14

    Topics: Adult; Blood Glucose; Body Weight; C-Peptide; Diabetes Mellitus; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Male; Middle Aged

1982
Mechanisms of insulin resistance following injury.
    Annals of surgery, 1982, Volume: 196, Issue:4

    Topics: Adult; Blood Glucose; Female; Glucagon; Humans; Hyperglycemia; Insulin; Insulin Resistance; Male; Middle Aged; Wounds and Injuries

1982
Evaluation of insulin resistance in non-obese subjects with impaired glucose tolerance.
    Diabete & metabolisme, 1982, Volume: 8, Issue:3

    Topics: Blood Glucose; C-Peptide; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Glucose Tolerance Test; Glycerol; Humans; Insulin; Insulin Resistance; Kinetics; Male; Propranolol; Reference Values

1982
[Changes in carbohydrate metabolism in hepatic cirrhosis].
    Revista clinica espanola, 1983, Mar-31, Volume: 168, Issue:6

    Topics: Carbohydrate Metabolism; Diabetes Mellitus; Glucagon; Glucose Tolerance Test; Humans; Insulin Resistance; Liver Cirrhosis; Male; Middle Aged

1983
Therapy of insulin-independent diabetes mellitus: general considerations.
    Metabolism: clinical and experimental, 1980, Volume: 29, Issue:5

    Topics: Blood Glucose; Diabetes Mellitus; Glucagon; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Obesity; Reference Values; Tolbutamide

1980
Resistance to insulin but not to glucagon in lean human hypertriglyceridemics.
    Diabetes, 1980, Volume: 29, Issue:11

    Topics: Adult; Blood Glucose; Cholesterol; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperlipoproteinemia Type IV; Insulin; Insulin Resistance; Kinetics; Male; Middle Aged; Reference Values; Triglycerides

1980
[Investigation of insulin resistance in fourteen children starting a diabetes mellitus (author's transl)].
    Annales de pediatrie, 1981, Volume: 28, Issue:7

    Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Fatty Acids; Female; Glucagon; Humans; Hydrocortisone; Insulin; Insulin Resistance; Male; Triglycerides

1981
[Hyperinsulinism and peripheral resistance to insulin in a case of leprechaunism].
    Anales espanoles de pediatria, 1981, Volume: 15, Issue:5

    Topics: Blood Glucose; Dietary Carbohydrates; Dwarfism; Female; Glucagon; Humans; Hyperinsulinism; Infant; Insulin; Insulin Resistance

1981
[Carbohydrate metabolic disorders in pancreonecrosis in the acute phase and in chronic conditions].
    Klinicheskaia meditsina, 1982, Volume: 60, Issue:4

    Topics: Adult; Blood Glucose; Carbohydrates; Female; Glucagon; Growth Hormone; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Necrosis; Pancreatic Diseases

1982
Insulin resistance and hyperinsulinaemia in mild to moderate progressive chronic renal failure and its association with aerobic work capacity.
    Diabetologia, 1995, Volume: 38, Issue:5

    Topics: Adult; Aerobiosis; Aged; Blood Glucose; Cardiac Output; Case-Control Studies; Fatty Acids, Nonesterified; Female; Glomerular Filtration Rate; Glucagon; Glucose Clamp Technique; Glucose Tolerance Test; Growth Hormone; Hemodynamics; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Kidney Failure, Chronic; Male; Middle Aged; Oxygen Consumption; Physical Exertion; Reference Values; Stroke Volume; Work Capacity Evaluation

1995
Insulin sensitivity, hormonal levels and skeletal muscle protein metabolism in tumour-bearing exercising rats.
    European journal of cancer (Oxford, England : 1990), 1995, Volume: 31A, Issue:1

    Topics: Animals; Female; Glucagon; Hydrocortisone; In Vitro Techniques; Insulin; Insulin Resistance; Muscle Proteins; Muscle, Skeletal; Neoplasms, Experimental; Physical Conditioning, Animal; Rats; Rats, Inbred WF; RNA

1995
Splanchnic infusions of short chain fatty acids do not change insulin sensitivity of pigs.
    The Journal of nutrition, 1995, Volume: 125, Issue:10

    Topics: Acetates; Acetic Acid; Animals; Blood Glucose; Butyrates; Fatty Acids, Nonesterified; Fatty Acids, Volatile; Female; Glucagon; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Insulin Resistance; Propionates; Random Allocation; Somatostatin; Swine; Tolbutamide

1995
Hyperinsulinemia in children and adolescents after bone marrow transplantation.
    Bone marrow transplantation, 1995, Volume: 15, Issue:6

    Topics: Adolescent; Anemia, Aplastic; Antineoplastic Combined Chemotherapy Protocols; Autoantibodies; Blood Glucose; Bone Marrow Transplantation; C-Peptide; Child; Child, Preschool; Female; Glucagon; Glycated Hemoglobin; Growth Hormone; Humans; Hypogonadism; Hypothyroidism; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Leukemia; Lymphoma, Non-Hodgkin; Male; Prospective Studies; Radiation Injuries; Radioisotope Teletherapy; Whole-Body Irradiation

1995
Excessive glucose production, rather than insulin resistance, accounts for hyperglycaemia in recent-onset streptozotocin-diabetic rats.
    Diabetologia, 1995, Volume: 38, Issue:3

    Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Glucagon; Glucose; Glucose Clamp Technique; Glycogen; Glycolysis; Hyperglycemia; Insulin; Insulin Resistance; Liver; Liver Glycogen; Male; Muscle, Skeletal; Myocardium; Organ Specificity; Rats; Rats, Wistar; Reference Values

1995
Adaptations in glucose homeostasis during chronic nutritional deprivation in rats: hepatic resistance to both insulin and glucagon.
    Metabolism: clinical and experimental, 1995, Volume: 44, Issue:6

    Topics: Adaptation, Physiological; Animals; Blood Glucose; Drug Resistance; Food Deprivation; Glucagon; Glucose Clamp Technique; Glycogen; Homeostasis; Insulin; Insulin Resistance; Liver; Male; Rats; Rats, Sprague-Dawley; Receptors, Glucagon; Time Factors; Weight Gain

1995
Modified glucagon test allowing simultaneous estimation of insulin secretion and insulin sensitivity: application to obesity, insulin-dependent diabetes mellitus, and noninsulin-dependent diabetes mellitus.
    The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:2

    Topics: Adult; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Insulin; Insulin Resistance; Insulin Secretion; Male; Obesity

1995
Insulin resistance in microvascular angina (syndrome X)
    Lancet (London, England), 1993, Jul-17, Volume: 342, Issue:8864

    Topics: Alanine; Angina Pectoris; Basal Metabolism; Blood Glucose; C-Peptide; Chest Pain; Coronary Circulation; Energy Metabolism; Fatty Acids, Nonesterified; Female; Forearm; Glucagon; Gluconeogenesis; Glucose Clamp Technique; Growth Hormone; Humans; Insulin; Insulin Resistance; Lactates; Male; Microcirculation; Middle Aged; Regional Blood Flow; Syndrome

1993
Glucoregulation and hormonal changes during prolonged exercise in boys and girls.
    European journal of applied physiology and occupational physiology, 1994, Volume: 68, Issue:1

    Topics: Blood Glucose; Child; Epinephrine; Exercise; Fatty Acids, Nonesterified; Female; Glucagon; Glycerol; Hormones; Humans; Insulin; Insulin Resistance; Male; Norepinephrine; Sex Characteristics

1994
[A study on the mechanism of hyperinsulinemia in essential hypertension].
    Zhonghua xin xue guan bing za zhi, 1993, Volume: 21, Issue:5

    Topics: Adult; Aged; Blood Glucose; C-Peptide; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypertension; Insulin; Insulin Resistance; Male; Middle Aged

1993
Octreotide: a long-acting inhibitor of endogenous hormone secretion for human metabolic investigations.
    Metabolism: clinical and experimental, 1994, Volume: 43, Issue:1

    Topics: Adult; Analysis of Variance; Blood Glucose; C-Peptide; Dose-Response Relationship, Drug; Female; Glucagon; Growth Hormone; Humans; Hyperglycemia; Hypoglycemia; Infusions, Intravenous; Insulin; Insulin Resistance; Male; Octreotide; Radioimmunoassay; Time Factors

1994
Effect of porcine somatotropin on the response of growing pigs to acute challenges of glucose, insulin and epinephrine and during a hyperinsulinemic-euglycemic clamp.
    Domestic animal endocrinology, 1993, Volume: 10, Issue:2

    Topics: Animals; Blood Glucose; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Glucose; Glucose Clamp Technique; Growth Hormone; Homeostasis; Infusions, Intravenous; Injections, Subcutaneous; Insulin; Insulin Resistance; Male; Random Allocation; Swine; Time Factors

1993
Insulin resistance, hypertension and microalbuminuria in patients with type 2 (non-insulin-dependent) diabetes mellitus.
    Diabetologia, 1993, Volume: 36, Issue:7

    Topics: Albuminuria; Blood Glucose; Blood Pressure; Body Mass Index; C-Peptide; Cholesterol; Cholesterol, HDL; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Fasting; Fatty Acids, Nonesterified; Glucagon; Glucose; Glycated Hemoglobin; Humans; Hypertension; Insulin; Insulin Resistance; Lipids; Liver; Middle Aged; Reference Values; Triglycerides

1993
Inhibitory effect of pregnancy on counterregulatory hormone responses to hypoglycemia in awake rat.
    Diabetes, 1993, Volume: 42, Issue:10

    Topics: 3-Hydroxybutyric Acid; Analysis of Variance; Animals; Blood Glucose; Epinephrine; Fasting; Female; Glucagon; Hydroxybutyrates; Hypoglycemia; Insulin; Insulin Resistance; Pregnancy; Pregnancy in Diabetics; Rats; Rats, Sprague-Dawley

1993
Study of the rate of early glucose disappearance following insulin injection: insulin sensitivity index.
    Diabetes research and clinical practice, 1993, Volume: 20, Issue:3

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Glucose Tolerance Test; Growth Hormone; Humans; Hydrocortisone; Hypertension; Insulin; Insulin Resistance; Male; Norepinephrine; Obesity; Polycystic Ovary Syndrome; Reference Values; Sex Factors

1993
Diabetes in chronic alcoholic pancreatitis. Role of residual beta cell function and insulin resistance.
    Digestive diseases and sciences, 1993, Volume: 38, Issue:3

    Topics: Alcoholism; Blood Glucose; Chronic Disease; Diabetes Complications; Diabetes Mellitus; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Islets of Langerhans; Male; Middle Aged; Pancreatitis

1993
The relation between clinical manifestations of polycystic ovary syndrome and beta-cell function.
    Clinical endocrinology, 1993, Volume: 38, Issue:3

    Topics: Adult; Blood Glucose; C-Peptide; Fatty Acids, Nonesterified; Female; Glucagon; Humans; Insulin; Insulin Resistance; Insulin-Like Growth Factor I; Islets of Langerhans; Obesity; Polycystic Ovary Syndrome; Sex Hormone-Binding Globulin; Testosterone

1993
Impaired glucose tolerance after endurance exercise is associated with reduced insulin secretion rather than altered insulin sensitivity.
    Metabolism: clinical and experimental, 1993, Volume: 42, Issue:3

    Topics: Adult; Blood Glucose; C-Peptide; Carbohydrate Metabolism; Electronic Data Processing; Exercise; Fatty Acids, Nonesterified; Glucagon; Glucose; Glucose Tolerance Test; Humans; Injections, Intravenous; Insulin; Insulin Resistance; Middle Aged; Norepinephrine; Physical Endurance; Radioimmunoassay; Rest; Running; Time Factors

1993
Rats with portal-caval vein transposition show hyperinsulinemia and insulin resistance.
    Metabolism: clinical and experimental, 1996, Volume: 45, Issue:1

    Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Glucagon; Glucose Tolerance Test; Hyperinsulinism; Insulin; Insulin Resistance; Liver; Male; Pancreas; Portal Vein; Portasystemic Shunt, Surgical; Rats; Rats, Sprague-Dawley; Time Factors; Vena Cava, Inferior

1996
Androgens and insulin resistance in type 1 diabetic men.
    Clinical endocrinology, 1995, Volume: 43, Issue:5

    Topics: Adult; Calorimetry, Indirect; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glucagon; Glycogen Synthase; Growth Hormone; Humans; Hydrocortisone; Insulin; Insulin Resistance; Insulin-Like Growth Factor Binding Protein 1; Lipid Peroxidation; Male; Muscle, Skeletal; Sex Hormone-Binding Globulin; Testosterone

1995
Effects of a change in the pattern of insulin delivery on carbohydrate tolerance in diabetic and nondiabetic humans in the presence of differing degrees of insulin resistance.
    The Journal of clinical investigation, 1996, May-15, Volume: 97, Issue:10

    Topics: Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Obesity

1996
NMR studies of muscle glycogen synthesis in insulin-resistant offspring of parents with non-insulin-dependent diabetes mellitus immediately after glycogen-depleting exercise.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, May-28, Volume: 93, Issue:11

    Topics: Adult; Analysis of Variance; Blood Glucose; Diabetes Mellitus, Type 2; Epinephrine; Female; Glucagon; Glucose; Glucose-6-Phosphate; Glucosephosphates; Glycogen; Humans; Hydrogen-Ion Concentration; Infusions, Intravenous; Insulin; Insulin Resistance; Lactates; Magnetic Resonance Spectroscopy; Male; Muscle Contraction; Muscle, Skeletal; Nuclear Family; Phosphates; Phosphocreatine; Physical Exertion; Reference Values

1996
Chromium and other insulin sensitizers may enhance glucagon secretion: implications for hypoglycemia and weight control.
    Medical hypotheses, 1996, Volume: 46, Issue:2

    Topics: Chromium; Down-Regulation; gamma-Aminobutyric Acid; Glucagon; Humans; Hypoglycemia; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Models, Biological; Weight Loss

1996
Causal linkage between insulin suppression of lipolysis and suppression of liver glucose output in dogs.
    The Journal of clinical investigation, 1996, Aug-01, Volume: 98, Issue:3

    Topics: Animals; Dogs; Fatty Acids, Nonesterified; Glucagon; Glucose; Glycerol; Insulin; Insulin Resistance; Lipolysis; Liver; Male

1996
Dietary rat models in which the development of hypertriglyceridemia and that of insulin resistance are dissociated.
    Metabolism: clinical and experimental, 1995, Volume: 44, Issue:12

    Topics: Animals; Blood Glucose; Corticosterone; Dietary Carbohydrates; Dietary Fats; Eating; Fasting; Fatty Acids, Nonesterified; Glucagon; Glucose Tolerance Test; Hypertriglyceridemia; Insulin; Insulin Resistance; Male; Polyethylene Glycols; Rats; Rats, Wistar; Triglycerides

1995
Impact of nicotinic acid treatment on insulin secretion and insulin sensitivity in low and high insulin responders.
    Scandinavian journal of clinical and laboratory investigation, 1996, Volume: 56, Issue:6

    Topics: Adult; Blood Glucose; Fatty Acids, Nonesterified; Female; Glucagon; Humans; Insulin; Insulin Antagonists; Insulin Resistance; Insulin Secretion; Male; Middle Aged; Niacin

1996
[How I explore... insulin secretion in clinical practice].
    Revue medicale de Liege, 1996, Volume: 51, Issue:10

    Topics: Basal Metabolism; Diabetes Mellitus; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Insulin Resistance; Insulin Secretion; Peptides

1996
The effect of pioglitazone on hepatic glucose uptake measured with indirect and direct methods in alloxan-induced diabetic dogs.
    Diabetes, 1997, Volume: 46, Issue:2

    Topics: Animals; Biological Transport; Blood Pressure; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dogs; Glucagon; Glucose; Hypoglycemic Agents; Insulin; Insulin Resistance; Liver; Pioglitazone; Thiazoles; Thiazolidinediones

1997
Dissociated insulinotropic sensitivity to glucose and carbachol in high-fat diet-induced insulin resistance in C57BL/6J mice.
    Metabolism: clinical and experimental, 1997, Volume: 46, Issue:1

    Topics: Animals; Blood Glucose; Body Weight; Carbachol; Cholesterol; Dietary Fats; Eating; Fatty Acids, Nonesterified; Female; Fluorescent Antibody Technique, Indirect; Galanin; Gene Expression; Genotype; Glucagon; Glucose; Immunohistochemistry; In Situ Hybridization; Insulin; Insulin Resistance; Islets of Langerhans; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Neuropeptide Y; Substance P; Triglycerides; Vasoactive Intestinal Peptide

1997
Effects of glucagon-like peptide-1 on islet function and insulin sensitivity in noninsulin-dependent diabetes mellitus.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:2

    Topics: Aged; Diabetes Mellitus, Type 2; Female; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Peptides

1997
Insulin resistance prevented by portal delivery of insulin in rats with renal subcapsular islet grafts.
    Diabetes, 1997, Volume: 46, Issue:3

    Topics: Anastomosis, Surgical; Animals; Blood Glucose; C-Peptide; Diabetes Mellitus, Experimental; Glucagon; Glucose Clamp Technique; Hyperinsulinism; Infusions, Intravenous; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans Transplantation; Liver; Male; Mesenteric Veins; Organ Size; Rats; Rats, Inbred Lew; Renal Veins

1997
Post-marathon paradox in IDDM: unchanged insulin sensitivity in spite of glycogen depletion.
    Diabetic medicine : a journal of the British Diabetic Association, 1997, Volume: 14, Issue:4

    Topics: Adult; Arteries; Blood Glucose; Creatine Kinase; Diabetes Mellitus, Type 1; Energy Metabolism; Fatty Acids, Nonesterified; Female; Forearm; Glucagon; Glucose Clamp Technique; Glycogen; Glycogen Synthase; Growth Hormone; Humans; Hydrocortisone; Insulin; Insulin Resistance; Lipid Metabolism; Male; Muscles; Myoglobin; Oxidation-Reduction; Running

1997
Theoretical analysis of the mechanisms of chronic hyperinsulinemia.
    Computers in biology and medicine, 1997, Volume: 27, Issue:3

    Topics: Adult; Blood Glucose; Computer Simulation; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glucagon; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Liver; Obesity; Software

1997
Site of insulin resistance after surgery: the contribution of hypocaloric nutrition and bed rest.
    Clinical science (London, England : 1979), 1997, Volume: 93, Issue:2

    Topics: Adult; Alanine; Bed Rest; Blood Glucose; Energy Intake; Female; Glucagon; Glucose Clamp Technique; Glutamine; Glycerol; Humans; Insulin Resistance; Male; Middle Aged; Postoperative Period; Surgical Procedures, Operative

1997
Seven days of euglycemic hyperinsulinemia induces insulin resistance for glucose metabolism but not hypertension, elevated catecholamine levels, or increased sodium retention in conscious normal rats.
    Diabetes, 1997, Volume: 46, Issue:10

    Topics: Animals; Blood Glucose; Blood Pressure; C-Peptide; Catecholamines; Glucagon; Glucose; Glucose Clamp Technique; Glycolysis; Heart Rate; Hyperinsulinism; Hypertension; Insulin Resistance; Liver; Male; Rats; Rats, Sprague-Dawley; Sodium

1997
Effect of moderate exercise on insulin sensitivity and substrate metabolism during post-exercise recovery in cirrhosis.
    Hepatology (Baltimore, Md.), 1997, Volume: 26, Issue:4

    Topics: Adult; Exercise; Female; Glucagon; Glucose; Humans; Insulin; Insulin Resistance; Lactic Acid; Liver Cirrhosis; Male; Middle Aged

1997
Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat.
    Diabetes, 1998, Volume: 47, Issue:3

    Topics: Animals; Apoptosis; Cohort Studies; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Glucagon; Glucose; Glucose Intolerance; Glucose Tolerance Test; Immunohistochemistry; In Vitro Techniques; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Pancreatic Polypeptide; Perfusion; Rats; Rats, Zucker; Somatostatin; Time Factors

1998
Impact of family history of diabetes on the assessment of beta-cell function.
    Metabolism: clinical and experimental, 1998, Volume: 47, Issue:5

    Topics: Adolescent; Adult; Age Factors; Aged; Biomarkers; Blood Glucose; Body Constitution; Body Mass Index; C-Peptide; Data Interpretation, Statistical; Diabetes Mellitus, Type 2; Family Health; Fasting; Female; Glucagon; Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Linear Models; Male; Middle Aged

1998
PACAP stimulates insulin secretion but inhibits insulin sensitivity in mice.
    The American journal of physiology, 1998, Volume: 274, Issue:5

    Topics: Animals; Drug Combinations; Epinephrine; Glucagon; Glucose; Injections, Intravenous; Insulin; Insulin Resistance; Insulin Secretion; Mice; Mice, Inbred Strains; Neuropeptides; Neurotransmitter Agents; Pituitary Adenylate Cyclase-Activating Polypeptide; Sodium Chloride

1998
Glucose turnover and insulin sensitivity in rats with pancreatic islet transplants.
    Diabetes, 1998, Volume: 47, Issue:7

    Topics: Anastomosis, Surgical; Animals; Blood Glucose; C-Peptide; Diabetes Mellitus, Experimental; Food; Glucagon; Glucose; Glucose Tolerance Test; Insulin; Insulin Resistance; Islets of Langerhans Transplantation; Kidney; Liver; Male; Mesenteric Veins; Rats; Rats, Inbred Lew; Renal Veins

1998
Tissue availability of insulin-like growth factor I is inversely related to insulin resistance in essential hypertension: effects of angiotensin converting enzyme inhibition.
    Journal of hypertension, 1998, Volume: 16, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Female; Follow-Up Studies; Glucagon; Growth Hormone; Humans; Hypertension; Insulin; Insulin Resistance; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Lisinopril; Male; Middle Aged; Radioimmunoassay

1998
Elevated serum tumour necrosis factor-alpha levels can contribute to the insulin resistance in Type II (non-insulin-dependent) diabetes and in obesity.
    Diabetologia, 1998, Volume: 41, Issue:7

    Topics: Age Factors; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Insulin Resistance; Male; Middle Aged; Obesity; Reference Values; Sex Characteristics; Tumor Necrosis Factor-alpha

1998
Potentiated beta-cell response to non-glucose stimuli in insulin-resistant C57BL/6J mice.
    European journal of pharmacology, 1998, Jun-05, Volume: 350, Issue:2-3

    Topics: Animals; Antimetabolites; Blood Glucose; Body Weight; Carbachol; Deoxyglucose; Diet; Female; Glucagon; Glucagon-Like Peptide 1; Glucose; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Peptide Fragments; Protein Precursors; Sincalide; Stimulation, Chemical

1998
Lack of defect in insulin action on hepatic glycogen synthase and phosphorylase in insulin-resistant monkeys.
    The American journal of physiology, 1998, Volume: 274, Issue:6

    Topics: Adipose Tissue; Animals; Glucagon; Glucose Clamp Technique; Glycogen Synthase; Insulin; Insulin Resistance; Liver; Macaca mulatta; Male; Muscle, Skeletal; Obesity; Omentum; Phosphorylases

1998
An insulin-dependent hypoglycaemia induced by electroacupuncture at the Zhongwan (CV12) acupoint in diabetic rats.
    Diabetologia, 1999, Volume: 42, Issue:2

    Topics: Acupuncture Points; Animals; beta-Endorphin; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Electroacupuncture; Glucagon; Hypoglycemia; Insulin; Insulin Resistance; Male; Naloxone; Narcotic Antagonists; Rats; Rats, Wistar; Tolbutamide

1999
Surgery-induced insulin resistance in human patients: relation to glucose transport and utilization.
    The American journal of physiology, 1999, Volume: 276, Issue:4

    Topics: Arthroplasty, Replacement, Hip; Blood Glucose; Cell Membrane; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glucose Transporter Type 4; Humans; Hydrocortisone; Hyperinsulinism; Insulin; Insulin Resistance; Lactates; Male; Middle Aged; Monitoring, Intraoperative; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Postoperative Period

1999
Effect of large bowel fermentation on insulin, glucose, free fatty acids, and glucagon-like peptide 1 (7-36) amide in patients with coronary heart disease.
    Nutrition (Burbank, Los Angeles County, Calif.), 1999, Volume: 15, Issue:3

    Topics: Aged; Blood Glucose; Coronary Disease; Fatty Acids, Nonesterified; Fermentation; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Intestinal Absorption; Intestine, Large; Lactulose; Male; Middle Aged; Peptide Fragments; Risk Factors

1999
Apoptosis and remodelling of beta cells by paracrine interferon-gamma without insulitis in transgenic mice.
    Diabetologia, 1999, Volume: 42, Issue:5

    Topics: Animals; Apoptosis; Female; Gene Expression; Glucagon; Glucose; Glucose Tolerance Test; In Situ Nick-End Labeling; Insulin; Insulin Resistance; Insulin Secretion; Interferon-gamma; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Promoter Regions, Genetic; Rats; Tumor Necrosis Factor-alpha

1999
The European Association for the Study of Diabetes Annual Meeting, 1998. Treatment of type 2 diabetes and the pathogenesis of complications.
    Diabetes care, 1999, Volume: 22, Issue:7

    Topics: Diabetes Mellitus; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Insulin Resistance; Obesity; Peptide Fragments; Protein Precursors

1999
Insulin resistance in HIV protease inhibitor-associated diabetes.
    Journal of acquired immune deficiency syndromes (1999), 1999, Jul-01, Volume: 21, Issue:3

    Topics: Adult; Animals; Anti-HIV Agents; C-Peptide; Cells, Cultured; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Glucagon; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Insulin; Insulin Resistance; Islets of Langerhans; Male; Phospholipases A; Proinsulin; Rats; Rats, Sprague-Dawley

1999
The incretins--outdated terminology in man?
    Diabetologia, 1999, Volume: 42, Issue:9

    Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin; Insulin Resistance; Insulin Secretion; Papio; Peptide Fragments; Protein Precursors

1999
Serum glucagon concentration and hyperinsulinaemia influence renal haemodynamics and urinary protein loss in normotensive patients with central obesity.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1999, Volume: 23, Issue:9

    Topics: Adult; Analysis of Variance; Cardiovascular Diseases; Case-Control Studies; Fatty Acids, Nonesterified; Female; Glomerular Filtration Rate; Glucagon; Glucose Tolerance Test; Glycoproteins; Hemodynamics; Humans; Hyperinsulinism; Immunoglobulin G; Insulin; Insulin Resistance; Kidney; Male; Membrane Glycoproteins; Middle Aged; Obesity; Proteinuria; Risk Factors; Trypsin Inhibitor, Kunitz Soybean

1999
Insulin resistant subjects lack islet adaptation to short-term dexamethasone-induced reduction in insulin sensitivity.
    Diabetologia, 1999, Volume: 42, Issue:8

    Topics: Arginine; Blood Glucose; Dexamethasone; Fasting; Female; Glucagon; Glucocorticoids; Glucose Clamp Technique; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Infusions, Intravenous; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Middle Aged; Postmenopause

1999
Insulin action during variable hyperglycemic-hyperinsulinemic infusions in hyperandrogenic anovulatory patients and healthy women.
    Fertility and sterility, 1999, Volume: 72, Issue:3

    Topics: Adolescent; Adrenal Glands; Adult; Anovulation; Blood Glucose; Body Composition; C-Peptide; Female; Glucagon; Human Growth Hormone; Humans; Hyperandrogenism; Insulin; Insulin Resistance; Leuprolide; Middle Aged; Ovary; Prospective Studies; Steroids

1999
All patients with Werner's syndrome are insulin resistant, but only those who also have impaired insulin secretion develop overt diabetes.
    Diabetes care, 1999, Volume: 22, Issue:12

    Topics: Consanguinity; Female; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin Resistance; Male; Pedigree; Werner Syndrome

1999
Dose-related effects of GLP-1 on insulin secretion, insulin sensitivity, and glucose effectiveness in mice.
    The American journal of physiology, 1999, Volume: 277, Issue:6

    Topics: Animals; Blood Glucose; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Tolerance Test; Insulin; Insulin Resistance; Insulin Secretion; Mice; Mice, Inbred Strains; Peptide Fragments; Peptides; Protein Precursors

1999
Glucose intolerance caused by a defect in the entero-insular axis: a study in gastric inhibitory polypeptide receptor knockout mice.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Dec-21, Volume: 96, Issue:26

    Topics: Administration, Oral; Animals; Diabetes Mellitus, Type 2; Dietary Fats; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Intolerance; Glucose Tolerance Test; Homeostasis; Injections, Intraperitoneal; Insulin; Insulin Resistance; Insulin Secretion; Intestines; Islets of Langerhans; Mice; Mice, Knockout; Models, Biological; Peptide Fragments; Protein Precursors; Receptors, Gastrointestinal Hormone

1999
Vegan proteins may reduce risk of cancer, obesity, and cardiovascular disease by promoting increased glucagon activity.
    Medical hypotheses, 1999, Volume: 53, Issue:6

    Topics: Animals; Cardiovascular Diseases; China; Diet, Vegetarian; Female; Glucagon; Humans; Insulin; Insulin Resistance; Insulin-Like Growth Factor I; Lipids; Liver; Male; Neoplasms; Obesity; Plant Proteins, Dietary; Puberty; Risk Factors; Weight Loss

1999
Effects of glucocorticoids on hepatic sensitivity to insulin and glucagon in man.
    Clinical nutrition (Edinburgh, Scotland), 2000, Volume: 19, Issue:1

    Topics: Adult; Dexamethasone; Female; Glucagon; Glucocorticoids; Glucose; Humans; Hyperinsulinism; Infusions, Intravenous; Insulin; Insulin Resistance; Liver; Male; Reference Values; Somatostatin; Time Factors

2000
Transgenic mice overexpressing insulin-like growth factor-II in beta cells develop type 2 diabetes.
    The Journal of clinical investigation, 2000, Volume: 105, Issue:6

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Fats; Fatty Liver; Gene Expression; Glucagon; Glucose; Glucose Tolerance Test; Hyperinsulinism; Hyperplasia; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Islets of Langerhans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Obesity; Promoter Regions, Genetic; Rats; Recombinant Fusion Proteins; RNA, Messenger

2000
Peripheral insulin sensitivity is decreased by elevated non-esterified fatty acid level in dexamethasone-treated rats.
    Diabetes, nutrition & metabolism, 1999, Volume: 12, Issue:4

    Topics: Animals; Dexamethasone; Fatty Acids, Nonesterified; Glucagon; Glucocorticoids; Insulin; Insulin Resistance; Male; Palmitic Acid; Rats; Rats, Wistar

1999
Beta-cell function of the pancreas after necrotizing pancreatitis.
    Digestive surgery, 1999, Volume: 16, Issue:6

    Topics: C-Peptide; Diabetes Mellitus; Female; Follow-Up Studies; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Islets of Langerhans; Male; Middle Aged; Pancreatitis, Acute Necrotizing; Postoperative Complications

1999
Islet dysfunction in insulin resistance involves impaired insulin secretion and increased glucagon secretion in postmenopausal women with impaired glucose tolerance.
    Diabetes care, 2000, Volume: 23, Issue:5

    Topics: Blood Pressure; Body Composition; Body Constitution; Body Mass Index; Female; Glucagon; Glucose Clamp Technique; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Middle Aged; Postmenopause

2000
Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice.
    Molecular cell, 2000, Volume: 6, Issue:1

    Topics: Animals; Base Sequence; CCAAT-Enhancer-Binding Proteins; DNA Primers; DNA-Binding Proteins; Gene Expression; Glucagon; Humans; In Vitro Techniques; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Lipodystrophy; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Mice, Transgenic; Models, Biological; Nuclear Proteins; Obesity; Phosphoproteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Transcription Factors

2000
Intractable hypoglycemia in a patient with diabetes mellitus, bilateral nephrectomy, and chronic active hepatitis.
    Clinical pediatrics, 2000, Volume: 39, Issue:9

    Topics: Adolescent; Diabetes Mellitus, Type 1; Diagnosis, Differential; Female; Glucagon; Hepatitis B, Chronic; Humans; Hyperinsulinism; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Kidney Failure, Chronic; Nephrectomy; Protein Synthesis Inhibitors; Substance Abuse, Intravenous; Treatment Outcome; Uremia

2000
Nonhepatic response to portal glucose delivery in conscious dogs.
    American journal of physiology. Endocrinology and metabolism, 2000, Volume: 279, Issue:6

    Topics: Animals; Consciousness; Dogs; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glycerol; Hepatic Veins; Insulin; Insulin Resistance; Lactic Acid; Liver; Liver Circulation; Male; Portal Vein; Signal Transduction

2000
Impaired neural regulation of insulin secretion related to the leptin receptor gene mutation in Wistar fatty rats.
    Physiology & behavior, 2000, Sep-15, Volume: 70, Issue:5

    Topics: Animals; Atropine Derivatives; Blood Glucose; Carrier Proteins; Crosses, Genetic; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Injections, Intraventricular; Insulin; Insulin Resistance; Insulin Secretion; Mutation; Obesity; Peptide Fragments; Protein Precursors; Rats; Rats, Inbred WKY; Rats, Zucker; Receptors, Cell Surface; Receptors, Leptin; Vagotomy; Vagus Nerve

2000
Early changes in islet hormone secretion in the hamster pancreatic cancer model.
    Teratogenesis, carcinogenesis, and mutagenesis, 2001, Volume: 21, Issue:1

    Topics: Adenocarcinoma; Amyloid; Animals; Carcinogens; Cricetinae; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Glucose Tolerance Test; Insulin; Insulin Resistance; Insulin Secretion; Islet Amyloid Polypeptide; Islets of Langerhans; Male; Mesocricetus; Nitrosamines; Pancreatic Juice; Pancreatic Neoplasms; Somatostatin

2001
Peripheral blood mitochondrial DNA content is inversely correlated with insulin secretion during hyperglycemic clamp studies in healthy young men.
    Diabetes research and clinical practice, 2001, Volume: 52, Issue:2

    Topics: Adult; Anthropometry; C-Peptide; DNA, Mitochondrial; Glucagon; Glucose Clamp Technique; Homeostasis; Humans; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Leukocytes; Male; Reference Values

2001
Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Jun-19, Volume: 98, Issue:13

    Topics: Animals; Blood Glucose; Fatty Acids, Nonesterified; Glucagon; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Heterozygote; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Leptin; Lipoprotein Lipase; Liver; Mice; Mice, Knockout; Mice, Transgenic; Muscle, Skeletal; Organ Specificity; Phosphatidylinositol 3-Kinases; Phosphoproteins; Signal Transduction; Triglycerides

2001
Effect of selective denervation of the rat pancreas on pancreatic endocrine function.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2001, Volume: 33, Issue:2

    Topics: Animals; Blood Glucose; Denervation; Glucagon; Glucose; Insulin; Insulin Resistance; Islets of Langerhans; Male; Pancreas; Rats; Rats, Sprague-Dawley; Reference Values

2001
Temporal changes in insulin sensitivity following the development of acute liver failure secondary to acetaminophen.
    Hepatology (Baltimore, Md.), 2001, Volume: 34, Issue:1

    Topics: Acetaminophen; Adult; Blood Glucose; C-Peptide; Fatal Outcome; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Insulin-Like Growth Factor I; Kinetics; Liver Failure, Acute; Male; Metabolic Clearance Rate; Middle Aged; Multiple Organ Failure

2001
Insulin resistance and type 2 diabetes: time for a new hypothesis.
    The New Zealand medical journal, 2001, May-25, Volume: 114, Issue:1132

    Topics: Amyloid; Animals; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin Resistance; Islet Amyloid Polypeptide; Leptin; Mice; Peptide Fragments; Protein Precursors; Tumor Necrosis Factor-alpha

2001
The role of postprandial releases of insulin and incretin hormones in meal-induced satiety--effect of obesity and weight reduction.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 2001, Volume: 25, Issue:8

    Topics: Absorptiometry, Photon; Adult; Appetite; Area Under Curve; Energy Intake; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Resistance; Insulin Secretion; Male; Middle Aged; Obesity; Peptide Fragments; Postprandial Period; Satiation; Weight Loss

2001
Insulin resistance induced in dairy steers by tumor necrosis factor alpha is partially reversed by 2,4-thiazolidinedione.
    Domestic animal endocrinology, 2001, Volume: 21, Issue:1

    Topics: Animals; Blood Glucose; Cattle; Fatty Acids, Nonesterified; Glucagon; Glucose; Growth Hormone; Growth Hormone-Releasing Hormone; Insulin; Insulin Resistance; Male; Random Allocation; Recombinant Proteins; Thiazoles; Thiazolidinediones; Tumor Necrosis Factor-alpha

2001
Hyperglycemia compensates for diet-induced insulin resistance in liver and skeletal muscle of rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 281, Issue:5

    Topics: Analysis of Variance; Animals; Body Weight; Diet; Dietary Fats; Dietary Sucrose; Glucagon; Glucose; Glucose Clamp Technique; Glycogen; Hyperglycemia; Insulin; Insulin Resistance; Liver; Male; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Starch

2001
Glucose kinetics and splanchnic uptake following mixed meal ingestion in cirrhotic-diabetic subjects.
    Diabetes, nutrition & metabolism, 2001, Volume: 14, Issue:6

    Topics: Adult; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Dietary Carbohydrates; Fatty Acids, Nonesterified; Female; Food; Glucagon; Humans; Hyperglycemia; Insulin; Insulin Resistance; Kinetics; Lactic Acid; Liver Cirrhosis; Male; Metabolic Clearance Rate; Middle Aged; Splanchnic Circulation

2001
Heterogeneous metabolic adaptation of C57BL/6J mice to high-fat diet.
    American journal of physiology. Endocrinology and metabolism, 2002, Volume: 282, Issue:4

    Topics: Adaptation, Physiological; Adipose Tissue, Brown; Animals; Blood Glucose; Diabetes Mellitus; Dietary Fats; Fatty Acids, Nonesterified; Glucagon; Glucose; Glucose Tolerance Test; Glucose Transporter Type 4; Insulin; Insulin Resistance; Leptin; Male; Mice; Mice, Inbred C57BL; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Myocardium; Obesity; RNA, Messenger; Weight Gain

2002
Hepatic insulin resistance in obese non-diabetic subjects and in type 2 diabetic patients.
    Obesity research, 2002, Volume: 10, Issue:3

    Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glucagon; Humans; Insulin; Insulin Resistance; Liver; Male; Middle Aged; Obesity; Somatostatin

2002
Abnormal release of incretins and cortisol after oral glucose in subjects with insulin-resistant myotonic dystrophy.
    European journal of endocrinology, 2002, Volume: 146, Issue:3

    Topics: Adult; Body Composition; DNA; Dose-Response Relationship, Drug; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Hydrocortisone; Insulin Resistance; Male; Middle Aged; Myotonic Dystrophy; Peptide Fragments; Regression Analysis; Repetitive Sequences, Nucleic Acid

2002
Glutamic acid decarboxylase antibody positivity is associated with an impaired insulin response to glucose and arginine in nondiabetic patients with autoimmune thyroiditis.
    The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:3

    Topics: Adult; Aged; Antibodies; Arginine; C-Peptide; Chronic Disease; Female; Follow-Up Studies; Glucagon; Glucose; Glutamate Decarboxylase; Humans; Injections, Intravenous; Insulin; Insulin Resistance; Islets of Langerhans; Male; Middle Aged; Thyroiditis, Autoimmune

2002
Exendin-4 increases insulin sensitivity via a PI-3-kinase-dependent mechanism: contrasting effects of GLP-1.
    Biochemical pharmacology, 2002, Mar-01, Volume: 63, Issue:5

    Topics: Animals; Drug Interactions; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucose; Insulin Resistance; Muscle, Skeletal; Peptide Fragments; Peptides; Phosphatidylinositol 3-Kinases; Protein Precursors; Rats; Tumor Cells, Cultured; Venoms

2002
Long-term inhibition of dipeptidyl peptidase IV improves glucose tolerance and preserves islet function in mice.
    European journal of endocrinology, 2002, Volume: 146, Issue:5

    Topics: Animals; Blood Glucose; Body Weight; Dietary Fats; Dipeptidyl Peptidase 4; Drinking; Eating; Female; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Intolerance; Insulin; Insulin Resistance; Intubation, Gastrointestinal; Islets of Langerhans; Mice; Mice, Inbred C57BL; Nitriles; Organ Size; Peptide Fragments; Protease Inhibitors; Protein Precursors; Pyrrolidines; Time Factors

2002
[Glucide intolerance and its pathogenic mechanisms during parenteral feeding].
    Annales de l'anesthesiologie francaise, 1977, Volume: 18, Issue:11

    Topics: Blood Glucose; Diuresis; Glucagon; Gluconeogenesis; Glycosuria; Humans; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Liver; Osmolar Concentration; Parenteral Nutrition; Risk

1977
Role of glucagon and other hormones in development of diabetic ketoacidosis.
    Lancet (London, England), 1975, Jun-14, Volume: 1, Issue:7920

    Topics: Adult; Blood Glucose; Catecholamines; Diabetes Mellitus; Diabetic Ketoacidosis; Fatty Acids, Nonesterified; Glucagon; Growth Hormone; Humans; Hydrocortisone; Insulin; Insulin Antagonists; Insulin Resistance; Keto Acids; Ketone Bodies; Lactates; Male

1975
Severe diabetic ketoacidosis.
    The Medical clinics of North America, 1978, Volume: 62, Issue:4

    Topics: Bicarbonates; Diabetic Ketoacidosis; Glucagon; Humans; Infusions, Parenteral; Injections, Intramuscular; Insulin; Insulin Resistance; Potassium

1978
Low-dose versus high-dose insulin therapy for diabetic ketoacidosis.
    Southern medical journal, 1979, Volume: 72, Issue:2

    Topics: Adult; Diabetic Ketoacidosis; Glucagon; Half-Life; Humans; Infusions, Parenteral; Injections, Subcutaneous; Insulin; Insulin Resistance; Middle Aged

1979
Insulin resistance caused by massive degradation of subcutaneous insulin.
    Diabetes, 1979, Volume: 28, Issue:7

    Topics: Adipose Tissue; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Ethylmaleimide; Female; Glucagon; Humans; Infusions, Parenteral; Injections, Intravenous; Injections, Subcutaneous; Insulin; Insulin Resistance

1979
Normalization of insulin and glucagon secretion in ketosis-resistant diabetes mellitus with prolonged diet therapy.
    The Journal of clinical endocrinology and metabolism, 1979, Volume: 49, Issue:6

    Topics: Adult; Diabetes Mellitus; Diabetic Ketoacidosis; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Male

1979
Congenital generalized lipodystrophy with insulin-resistant diabetes.
    European journal of pediatrics, 1978, Jan-17, Volume: 127, Issue:2

    Topics: Acanthosis Nigricans; Arginine; Child; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glucagon; Humans; Insulin Resistance; Leukocytes; Lipodystrophy; Lipoproteins, LDL; Male; Receptor, Insulin; Sulfonylurea Compounds; Triglycerides

1978
Congenital lipodystrophy: An endocrine study in three siblings. I. Disorders of carbohydrate metabolism.
    The Journal of pediatrics, 1978, Volume: 93, Issue:2

    Topics: Adolescent; Adrenocorticotropic Hormone; Antigens; Arginine; Blood Glucose; Child; Child, Preschool; Female; Glucagon; Glucose Tolerance Test; Growth Hormone; Hormones; Humans; Infant; Insulin; Insulin Resistance; Insulin Secretion; Lipid Metabolism; Lipodystrophy; Male; Tolbutamide

1978
Hormonal relationships of the endocrine pancreas in diabetes mellitus.
    Journal of the American Medical Women's Association (1972), 1979, Volume: 34, Issue:1

    Topics: Diabetes Mellitus; Glucagon; Humans; Insulin; Insulin Resistance; Pancreas; Pancreatic Hormones; Receptor, Insulin; Somatostatin

1979
Carbohydrate metabolism and insulin resistance in myotonia dystrophica.
    The Journal of clinical endocrinology and metabolism, 1977, Volume: 44, Issue:3

    Topics: Adult; Aged; Arginine; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus; Female; Fructose; Galactose; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Leucine; Male; Middle Aged; Myotonic Dystrophy; Sorbitol; Tolbutamide; Xylose

1977
Glucagon and insulin binding to liver membranes in a partially nephrectomized uremic rat model.
    The Journal of clinical investigation, 1977, Volume: 60, Issue:1

    Topics: Adenylyl Cyclases; Animals; Blood Urea Nitrogen; Cell Membrane; Creatinine; Disease Models, Animal; Glucagon; Glucose; Hyperglycemia; Hyperinsulinism; Hypersensitivity; Insulin; Insulin Resistance; Kidney; Liver; Nephrectomy; Protein Binding; Rats; Uremia

1977
Investigation of insulin resistance during diabetic ketoacidosis: role of counterregulatory substances and effect of insulin therapy.
    Metabolism: clinical and experimental, 1977, Volume: 26, Issue:10

    Topics: Adult; Blood Glucose; Child; Diabetic Ketoacidosis; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Growth Hormone; Humans; Hydrocortisone; Insulin; Insulin Resistance; Male

1977
Glucose tolerance, plasma insulin levels and insulin sensitivity in elderly patients.
    Age and ageing, 1979, Volume: 8, Issue:2

    Topics: Adult; Age Factors; Aged; Alanine; Blood Glucose; Fatty Acids; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Male

1979
Glucose, insulin and somatostatin infusion for the determination of insulin resistance in liver cirrhosis.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1979, Volume: 11, Issue:10

    Topics: Adult; Blood Glucose; Glucagon; Glucose; Humans; Insulin; Insulin Resistance; Liver Cirrhosis; Male; Middle Aged; Somatostatin

1979
[Diet and insulin resistance].
    Nederlands tijdschrift voor geneeskunde, 1978, Aug-05, Volume: 122, Issue:31

    Topics: Adult; Cell Membrane; Diabetes Mellitus; Diet, Reducing; Fatty Acids, Unsaturated; Glucagon; Humans; Insulin; Insulin Resistance; Middle Aged; Obesity; Receptor, Insulin

1978
Pathophysiology of diabetes mellitus.
    The Medical clinics of North America, 1978, Volume: 62, Issue:4

    Topics: Amino Acids; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Dietary Carbohydrates; Glucagon; Homeostasis; Humans; Insulin; Insulin Resistance; Insulin Secretion; Lipid Metabolism; Somatostatin

1978
Glucose kinetics and responsiveness to insulin in the rat injured by burn.
    Surgery, gynecology & obstetrics, 1978, Volume: 147, Issue:4

    Topics: Animals; Blood Glucose; Body Weight; Burns; Glucagon; Glucose; Hematocrit; Insulin; Insulin Resistance; Kinetics; Male; Rats

1978
[Insulin resistance not due to antibodies].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1978, Issue:84

    Topics: Blood Glucose; Glucagon; Humans; Hyperlipidemias; Insulin; Insulin Resistance; Obesity; Triglycerides

1978
Successful immunosuppressive therapy in insulin resistant diabetes caused by anti-insulin receptor autoantibodies.
    The Journal of clinical endocrinology and metabolism, 1977, Volume: 44, Issue:1

    Topics: Autoantibodies; C-Peptide; Cyclophosphamide; Diabetes Complications; Diabetes Mellitus; Female; Glucagon; Humans; Immunosuppressive Agents; Insulin; Insulin Antibodies; Insulin Resistance; Middle Aged; Prednisolone; Receptor, Insulin; Sjogren's Syndrome

1977
Does glucagon play a role in the insulin resistance of patients with adult non-ketotic diabetes?
    Diabetologia, 1977, Volume: 13, Issue:4

    Topics: Adult; Blood Glucose; Diabetes Mellitus; Fasting; Glucagon; Humans; Hyperglycemia; Insulin; Insulin Resistance; Middle Aged

1977
Plasma glucagon levels in normal women during pregnancy.
    Diabetologia, 1975, Volume: 11, Issue:6

    Topics: Adult; Blood Glucose; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Tolerance Test; Heparin; Humans; Insulin; Insulin Resistance; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Triglycerides

1975
Effects of islet amyloid polypeptide on hepatic insulin resistance and glucose production in the isolated perfused rat liver.
    Diabetologia, 1992, Volume: 35, Issue:2

    Topics: Amyloid; Animals; Cyclic AMP; Glucagon; Gluconeogenesis; In Vitro Techniques; Insulin; Insulin Resistance; Islet Amyloid Polypeptide; Kinetics; Lactates; Liver; Liver Glycogen; Male; Perfusion; Rats; Rats, Inbred Strains; Time Factors

1992
The dawn phenomenon: comparison between normal and insulin-dependent diabetic adolescents.
    Pediatric research, 1992, Volume: 31, Issue:3

    Topics: Adolescent; Adrenocorticotropic Hormone; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Insulin; Insulin Resistance; Male

1992
Characterization of the insulin resistance in liver cirrhosis: a comparison with non-insulin dependent diabetes mellitus.
    Endocrinologia japonica, 1992, Volume: 39, Issue:5

    Topics: C-Peptide; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Erythrocytes; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Clamp Technique; Glucose Tolerance Test; Growth Hormone; Humans; Hydrocortisone; Insulin; Insulin Resistance; Liver Cirrhosis; Male; Metabolic Clearance Rate; Middle Aged; Receptor, Insulin

1992
The effect of tolbutamide on burn hypermetabolism.
    Burns : journal of the International Society for Burn Injuries, 1992, Volume: 18, Issue:6

    Topics: Adult; Animals; Blood Glucose; Burns; Energy Metabolism; Female; Glucagon; Humans; Insulin; Insulin Resistance; Male; Oxygen Consumption; Prospective Studies; Rabbits; Tolbutamide

1992
Markedly reduced beta-cell function does not result in insulin resistance in islet autografted dogs.
    Diabetes, 1992, Volume: 41, Issue:9

    Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Dogs; Female; Glucagon; Insulin; Insulin Resistance; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Pancreatectomy; Transplantation, Autologous

1992
Idiopathic reactive hypoglycemia: a role for glucagon?
    Journal of endocrinological investigation, 1992, Volume: 15, Issue:4

    Topics: Adult; Blood Glucose; Female; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Insulin Resistance; Male

1992
Recovery and hypersecretion of insulin and reversal of insulin resistance after withdrawal of short-term cyclosporine treatment.
    Transplantation, 1992, Volume: 53, Issue:6

    Topics: Animals; Body Weight; Cyclosporine; Dogs; Dose-Response Relationship, Drug; Glucagon; Glucose Clamp Technique; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male

1992
[Glucose tolerance in the elderly--changes in insulin, C-peptide and glucagon secretion].
    Wiener medizinische Wochenschrift (1946), 1992, Volume: 142, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aging; C-Peptide; Female; Glucagon; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Insulin; Insulin Resistance; Male; Reference Values

1992
Encainide-induced diabetes: analysis of islet cell function.
    Research communications in chemical pathology and pharmacology, 1992, Volume: 76, Issue:3

    Topics: Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Diet; Encainide; Glucagon; Humans; Hyperglycemia; Insulin Resistance; Islets of Langerhans; Male

1992
Insulin resistance and action in hypertriglyceridemia.
    Diabetes research and clinical practice, 1991, Volume: 14, Issue:1

    Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Fatty Acids, Nonesterified; Glucagon; Glucose Clamp Technique; Glycerol; Humans; Hydroxybutyrates; Hypertriglyceridemia; Infusions, Intravenous; Insulin; Insulin Resistance; Kinetics; Lactates; Male; Middle Aged; Pyruvates; Reference Values; Triglycerides

1991
Abnormal glucagon response to arginine and its normalization in obese hyperinsulinaemic patients with glucose intolerance: importance of insulin action on pancreatic alpha cells.
    Diabetologia, 1991, Volume: 34, Issue:11

    Topics: Adult; Arginine; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Obesity; Reference Values

1991
Effect of physiologic hyperinsulinemia on glucose and lipid metabolism in cirrhosis.
    The Journal of clinical investigation, 1991, Volume: 88, Issue:2

    Topics: Adult; Aged; Blood Glucose; Body Constitution; Catecholamines; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Tolerance Test; Growth Hormone; Humans; Insulin; Insulin Resistance; Lipids; Liver; Liver Cirrhosis; Male; Middle Aged; Oxidation-Reduction

1991
Insulin sensitivity and insulin clearance in human immunodeficiency virus-infected men.
    Metabolism: clinical and experimental, 1991, Volume: 40, Issue:6

    Topics: Adult; Blood Glucose; C-Peptide; Epinephrine; Glucagon; Glucose; Growth Hormone; HIV Infections; Humans; Hydrocortisone; Insulin; Insulin Infusion Systems; Insulin Resistance; Male; Metabolic Clearance Rate; Middle Aged; Norepinephrine; Reference Values

1991
[Apollinaire Bouchardat 1991 Award. Insulin resistance in an animal model of hypoinsulinism].
    Journees annuelles de diabetologie de l'Hotel-Dieu, 1991

    Topics: Animals; Blood Glucose; Disease Models, Animal; Female; Glucagon; Gluconeogenesis; Insulin; Insulin Resistance; Lactation; Metabolic Diseases; Rats

1991
Influence of glucagon on protein and leucine metabolism: a study in fasting man with induced insulin resistance.
    The British journal of surgery, 1990, Volume: 77, Issue:7

    Topics: Adult; Fasting; Female; Forearm; Glucagon; Humans; Insulin Resistance; Leucine; Male; Muscles; Proteins; Somatostatin

1990
[Glucose intolerance in pituitary disease].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49 Suppl

    Topics: Acromegaly; Bromocriptine; Cushing Syndrome; Glucagon; Gluconeogenesis; Glucose; Glucose Tolerance Test; Humans; Hypopituitarism; Insulin Resistance; Liver

1991
Evidence for an insulin resistance in the adult offspring of pregnant streptozotocin-diabetic rats.
    Diabetologia, 1991, Volume: 34, Issue:2

    Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Clamp Technique; Insulin; Insulin Infusion Systems; Insulin Resistance; Pregnancy; Pregnancy in Diabetics; Rats; Rats, Inbred Strains; Reference Values

1991
Amylin-induced in vivo insulin resistance in conscious rats: the liver is more sensitive to amylin than peripheral tissues.
    Diabetologia, 1991, Volume: 34, Issue:4

    Topics: Amyloid; Animals; Cell Line; Corticosterone; Epinephrine; Glucagon; Glucose; Glucose Clamp Technique; Insulin; Insulin Resistance; Islet Amyloid Polypeptide; Liver; Male; Norepinephrine; Organ Specificity; Rats; Rats, Inbred Strains; Receptor, Insulin

1991
Insulin resistance in type 1 (insulin-dependent) diabetes: dissimilarities for glucose and intermediary metabolites.
    Diabetes research (Edinburgh, Scotland), 1990, Volume: 15, Issue:1

    Topics: Adult; Blood Glucose; Body Mass Index; C-Peptide; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Clamp Technique; Glycated Hemoglobin; Glycerol; Humans; Insulin; Insulin Antibodies; Insulin Resistance; Ketone Bodies; Male; Reference Values

1990
Inhibition of insulin release by cyclosporine and production of peripheral insulin resistance in the dog.
    Transplantation, 1990, Volume: 49, Issue:3

    Topics: Animals; Blood Glucose; Cyclosporins; Dogs; Glucagon; Insulin; Insulin Resistance; Insulin Secretion; Liver; Secretory Rate

1990
Glucoregulation and hormonal responses to maximal exercise in non-insulin-dependent diabetes.
    Journal of applied physiology (Bethesda, Md. : 1985), 1990, Volume: 68, Issue:5

    Topics: Blood Glucose; Diabetes Mellitus, Type 2; Epinephrine; Exercise; Glucagon; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Norepinephrine

1990
Characterization of the late posthypoglycemic insulin resistance in insulin-dependent diabetes mellitus.
    Metabolism: clinical and experimental, 1990, Volume: 39, Issue:8

    Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose; Glucose Clamp Technique; Glycated Hemoglobin; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Insulin Resistance; Male; Random Allocation

1990
Reduced insulin secretion by subtotal pancreatectomy: preservation of insulin sensitivity and glucose tolerance in postoperative patients.
    Scandinavian journal of gastroenterology, 1990, Volume: 25, Issue:7

    Topics: Aged; Blood Glucose; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Male; Pancreas; Pancreatectomy

1990
Treatment with a somatostatin analog decreases pancreatic B-cell and whole body sensitivity to glucose.
    The Journal of clinical endocrinology and metabolism, 1990, Volume: 71, Issue:4

    Topics: Adult; Catecholamines; Fasting; Glucagon; Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Octreotide; Secretory Rate

1990
Intraportal hyperinsulinemia decreases insulin-stimulated glucose uptake in the dog.
    Metabolism: clinical and experimental, 1990, Volume: 39, Issue:2

    Topics: Animals; Blood Glucose; Dogs; Epinephrine; Glucagon; Glucose; Hydrocortisone; Hyperinsulinism; Infusions, Intravenous; Insulin; Insulin Resistance; Portal Vein; Time Factors

1990
The second-messenger system for peptide hormones.
    Hospital practice (Office ed.), 1989, Aug-15, Volume: 24, Issue:8

    Topics: Adult; Animals; Cell Communication; Cyclic AMP; Dogs; Female; Glucagon; Glycogen; Homeostasis; Hormones; Humans; Infant, Newborn; Insulin; Insulin Resistance; Male; Peptides; Protein Kinases; Second Messenger Systems; Signal Transduction

1989
Multiple defects occur in the guanine nucleotide regulatory protein system in liver plasma membranes of obese (fa/fa) but not lean (Fa/Fa) Zucker rats: loss of functional Gi and abnormal Gs function.
    Cellular signalling, 1989, Volume: 1, Issue:1

    Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Blotting, Western; Cell Membrane; Cholera Toxin; Colforsin; Diabetes Mellitus, Experimental; Glucagon; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Insulin Resistance; Liver; Male; NAD; Obesity; Pertussis Toxin; Phosphorus Radioisotopes; Rats; Rats, Inbred Strains; Rats, Zucker; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Virulence Factors, Bordetella

1989
Glucose intolerance in uremic patients: the relative contributions of impaired beta-cell function and insulin resistance.
    Clinical nephrology, 1989, Volume: 31, Issue:4

    Topics: Adult; Aged; Blood Glucose; Female; Glucagon; Glucose; Glucose Tolerance Test; Growth Hormone; Humans; Insulin; Insulin Resistance; Islets of Langerhans; Male; Middle Aged; Somatostatin; Uremia

1989
Indirect effect of catecholamines on development of insulin resistance in skeletal muscle from diabetic rats.
    Diabetes, 1989, Volume: 38, Issue:7

    Topics: Adrenergic beta-Antagonists; Animals; Biological Transport; Blood Glucose; Catecholamines; Diabetes Mellitus, Experimental; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Glucose; Glycogen; Insulin; Insulin Resistance; Male; Muscles; Propranolol; Rats; Rats, Inbred Strains; Streptozocin

1989
Contribution of insulin resistance to catabolic effect of prednisone on leucine metabolism in humans.
    Diabetes, 1989, Volume: 38, Issue:10

    Topics: Adult; Basal Metabolism; Glucagon; Glucose; Growth Hormone; Humans; Insulin; Insulin Infusion Systems; Insulin Resistance; Kinetics; Leucine; Models, Theoretical; Oxidation-Reduction; Prednisone; Reference Values; Somatostatin

1989
Reversal of in vitro hepatic insulin resistance in chronic pancreatitis by pancreatic polypeptide in the rat.
    Surgery, 1989, Volume: 106, Issue:6

    Topics: Animals; Blood Glucose; Chronic Disease; Glucagon; Glucose; Insulin Resistance; Liver; Male; Oleic Acid; Oleic Acids; Pancreatic Polypeptide; Pancreatitis; Rats; Rats, Inbred Strains; Reference Values

1989
Estimates of in vivo insulin action in man: comparison of insulin tolerance tests with euglycemic and hyperglycemic glucose clamp studies.
    The Journal of clinical endocrinology and metabolism, 1989, Volume: 68, Issue:2

    Topics: Adult; Blood Glucose; C-Peptide; Epinephrine; Female; Glucagon; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Insulin Infusion Systems; Insulin Resistance; Male; Norepinephrine; Obesity

1989
Increased beta-cell secretory capacity as mechanism for islet adaptation to nicotinic acid-induced insulin resistance.
    Diabetes, 1989, Volume: 38, Issue:5

    Topics: Adult; Blood Glucose; Epinephrine; Glucagon; Humans; Hydrocortisone; Injections, Intravenous; Insulin Resistance; Islets of Langerhans; Male; Nicotinic Acids; Norepinephrine

1989
Effect of interferon on glucose tolerance and insulin sensitivity.
    Diabetes, 1989, Volume: 38, Issue:5

    Topics: Adult; Blood Glucose; C-Peptide; Circadian Rhythm; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Tolerance Test; Humans; Hydrocortisone; Insulin; Insulin Resistance; Interferon Type I; Male

1989
In vitro hepatic insulin resistance in chronic pancreatitis in the rat.
    The Journal of surgical research, 1989, Volume: 46, Issue:5

    Topics: Animals; Blood Glucose; Chronic Disease; Glucagon; Glucose; Glycogen; Insulin; Insulin Resistance; Liver; Male; Pancreatitis; Perfusion; Rats; Rats, Inbred Strains

1989
Insulin-sensitive and insulin-resistant variants in NIDDM.
    Diabetes, 1989, Volume: 38, Issue:6

    Topics: Adult; Autoantibodies; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Liver; Male; Middle Aged

1989
In vivo insulin resistance during nonlethal hypermetabolic sepsis.
    Circulatory shock, 1989, Volume: 28, Issue:2

    Topics: Animals; Blood Glucose; Escherichia coli Infections; Fasting; Glucagon; Glucose; Insulin; Insulin Resistance; Lactates; Lactic Acid; Liver; Male; Rats; Rats, Inbred Strains; Sepsis

1989
Insulin and glucagon degradation in liver are not affected by hepatic cirrhosis.
    Clinica chimica acta; international journal of clinical chemistry, 1989, Aug-31, Volume: 183, Issue:3

    Topics: Adult; Aged; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Liver; Liver Cirrhosis; Male; Middle Aged

1989
Insulin resistance in septic rats--a study by the euglycemic clamp technique.
    Life sciences, 1989, Volume: 45, Issue:17

    Topics: Animals; Blood Glucose; Epinephrine; Glucagon; Glucose Clamp Technique; Hydrocortisone; Insulin; Insulin Resistance; Liver; Male; Norepinephrine; Rats; Rats, Inbred Strains; Sepsis

1989
Normal insulin sensitivity during the phase of glucose intolerance but insulin resistance at the onset of diabetes in the spontaneously diabetic BB rat.
    Diabetologia, 1989, Volume: 32, Issue:12

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Crosses, Genetic; Diabetes Mellitus, Experimental; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glucose Clamp Technique; Hydroxybutyrates; Insulin; Insulin Resistance; Male; Norepinephrine; Prediabetic State; Rats; Rats, Inbred BB; Reference Values

1989
Hypoglycemia in IDDM.
    Diabetes, 1989, Volume: 38, Issue:9

    Topics: Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Insulin Resistance; Risk Factors

1989
Insulin resistance after oral glucose tolerance testing in patients with major depression.
    The American journal of psychiatry, 1988, Volume: 145, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Blood Glucose; Depressive Disorder; Female; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hydrocortisone; Insulin; Insulin Resistance; Male; Middle Aged; Personality Inventory; Psychiatric Status Rating Scales; Somatostatin

1988
Peripheral and hepatic resistance to insulin and hepatic resistance to glucagon in uraemic subjects. Studies at physiologic and supraphysiologic hormone levels.
    Acta endocrinologica, 1988, Volume: 118, Issue:1

    Topics: Adult; Aged; C-Peptide; Female; Glucagon; Glucose; Humans; Insulin; Insulin Resistance; Kinetics; Liver; Male; Middle Aged; Somatostatin; Uremia

1988
Somatostatin reduces posthypoglycemic insulin resistance in insulin-dependent diabetes mellitus.
    Acta endocrinologica, 1988, Volume: 118, Issue:2

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Insulin Resistance; Male; Somatostatin

1988
Sulfonylurea therapy fails to diminish insulin resistance in type I-diabetic subjects.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1986, Volume: 18, Issue:9

    Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Humans; Insulin; Insulin Resistance; Lipolysis; Liver; Male; Metabolic Clearance Rate; Middle Aged; Sulfonylurea Compounds

1986
Acromegaly and insulin resistance: a case study.
    Acta endocrinologica, 1986, Volume: 111, Issue:4

    Topics: Acromegaly; Adenoma, Acidophil; Bromocriptine; C-Peptide; Female; Glucagon; Glucose; Glucose Tolerance Test; Growth Hormone; Humans; Insulin; Insulin Resistance; Middle Aged; Pituitary Neoplasms; Tomography, X-Ray Computed

1986
Bed-rest-induced insulin resistance occurs primarily in muscle.
    Metabolism: clinical and experimental, 1988, Volume: 37, Issue:8

    Topics: Adult; Bed Rest; Glucagon; Gluconeogenesis; Growth Hormone; Humans; Hydrocortisone; Insulin; Insulin Resistance; Insulin-Like Growth Factor I; Liver; Male; Muscles

1988
Glucoregulation in acute liver failure.
    European journal of clinical investigation, 1986, Volume: 16, Issue:3

    Topics: Acute Disease; Adult; Blood Glucose; C-Peptide; Female; Glucagon; Glucose; Humans; Insulin; Insulin Resistance; Liver; Liver Diseases; Male; Middle Aged

1986
Protein-energy malnutrition in pregnant rats improves the adaptation of the endocrine pancreas in malnourished offspring and induces insulin resistance after rehabilitation.
    The British journal of nutrition, 1987, Volume: 58, Issue:3

    Topics: Adaptation, Physiological; Animals; Blood Glucose; Female; Glucagon; Homeostasis; Insulin; Insulin Resistance; Islets of Langerhans; Male; Pregnancy; Pregnancy Complications; Protein-Energy Malnutrition; Rats; Rats, Inbred Strains; Weaning

1987
Artificial induction of intravascular lipolysis by lipid-heparin infusion leads to insulin resistance in man.
    Diabetologia, 1988, Volume: 31, Issue:5

    Topics: Adult; Blood Glucose; C-Peptide; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Glucagon; Glycerol; Heparin; Humans; Insulin; Insulin Resistance; Kinetics; Lipolysis; Male; Triglycerides

1988
Insulin resistance and delayed clearance of peptide hormones in cirrhotic rat liver.
    The American journal of physiology, 1987, Volume: 252, Issue:6 Pt 1

    Topics: Animals; Blood Glucose; Glucagon; Growth Hormone; Half-Life; Insulin; Insulin Resistance; Liver; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Rats; Thioacetamide

1987
Reduction of glycogen stores in a rat model of chronic hyperinsulinism.
    Journal of endocrinological investigation, 1987, Volume: 10, Issue:3

    Topics: Adrenal Glands; Animals; Blood Glucose; Chronic Disease; Disease Models, Animal; Glucagon; Glycogen; Hyperinsulinism; Insulin; Insulin Resistance; Liver; Male; Muscles; Organ Size; Rats; Rats, Inbred Strains

1987
Antecedent chronic hyperglycaemia blocks phlorizin-induced insulin resistance in the dog.
    Diabetologia, 1988, Volume: 31, Issue:4

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dogs; Glucagon; Glycosuria; Hyperglycemia; Insulin Resistance; Kidney; Male; Phlorhizin

1988
Basal glucagon replacement in chronic glucagon deficiency increases insulin resistance.
    Diabetes, 1986, Volume: 35, Issue:5

    Topics: Adult; Aged; Blood Glucose; Female; Glucagon; Glucose; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Monocytes; Pancreatectomy

1986
Elevated growth hormone levels and insulin resistance in patients with cirrhosis of the liver.
    The American journal of the medical sciences, 1986, Volume: 291, Issue:4

    Topics: Adult; Blood Glucose; Glucagon; Glucose; Glucose Tolerance Test; Growth Hormone; Humans; Hydrocortisone; Insulin; Insulin Resistance; Liver Cirrhosis; Male; Metabolic Clearance Rate; Middle Aged; Time Factors

1986
Experimental hyperthyroidism does not induce hepatic insulin resistance in the miniature pig.
    The Biochemical journal, 1986, Mar-15, Volume: 234, Issue:3

    Topics: Animals; Blood Glucose; Glucagon; Gluconeogenesis; Hyperthyroidism; Hypothyroidism; Insulin; Insulin Resistance; Kinetics; Liver; Male; Swine

1986
[Insulin resistance in liver diseases].
    Zeitschrift fur Gastroenterologie, 1986, Volume: 24, Issue:8

    Topics: Blood Glucose; Fatty Acids, Nonesterified; Glucagon; Growth Hormone; Humans; Insulin; Insulin Resistance; Islets of Langerhans; Liver; Liver Diseases; Metabolic Clearance Rate; Proinsulin; Receptor, Insulin

1986
Insulin action in aging man: evidence for tissue-specific differences at low physiologic insulin levels.
    Journal of gerontology, 1987, Volume: 42, Issue:2

    Topics: Adult; Aged; Aging; Blood Glucose; C-Peptide; Female; Glucagon; Glucose; Humans; Insulin; Insulin Resistance; Lipolysis; Liver; Male

1987
Use of a variable insulin infusion to assess insulin action in obesity: defects in both the kinetics and amplitude of response.
    The Journal of clinical endocrinology and metabolism, 1987, Volume: 64, Issue:5

    Topics: Adult; Blood Glucose; Body Weight; C-Peptide; Glucagon; Glucose; Humans; Insulin; Insulin Resistance; Kinetics; Middle Aged; Obesity

1987
Increased glucose turnover and glucose cycling in acromegalic patients with normal glucose tolerance.
    Diabetologia, 1986, Volume: 29, Issue:11

    Topics: Acromegaly; Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus; Female; Glucagon; Glucose Tolerance Test; Glucose-6-Phosphate; Glucosephosphates; Humans; Insulin Resistance; Liver; Male; Middle Aged

1986
Insulin resistance and impaired insulin secretion in subjects with histories of gestational diabetes mellitus.
    Diabetes, 1985, Volume: 34, Issue:9

    Topics: Adult; Arginine; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Epinephrine; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Norepinephrine; Obesity; Pregnancy; Pregnancy in Diabetics

1985
Insulin receptors and insulin sensitivity in normo and hyperinsulinemic obese patients.
    Journal of endocrinological investigation, 1985, Volume: 8, Issue:3

    Topics: Adult; Blood Glucose; C-Peptide; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Middle Aged; Obesity; Receptor, Insulin

1985
Diazoxide prevents the development of hormonal and metabolic abnormalities present in rats fed a sucrose rich diet.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1985, Volume: 17, Issue:10

    Topics: Animals; Diazoxide; Dietary Carbohydrates; DNA; Glucagon; Heart; Hyperinsulinism; Insulin; Insulin Resistance; Liver; Male; Organ Size; Proteins; Rats; Rats, Inbred Strains; Sucrose; Triglycerides

1985
On the decrease of glucose tolerance in pregnancy. A review.
    Diabete & metabolisme, 1985, Volume: 11, Issue:5

    Topics: Blood Glucose; Fasting; Female; Glucagon; Humans; Hydrocortisone; Insulin; Insulin Resistance; Insulin Secretion; Pregnancy; Reference Values

1985
Carbohydrate intolerance in gonadal dysgenesis: evidence for insulin resistance and hyperglucagonemia.
    Hormone research, 1985, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Aging; Arginine; Blood Glucose; Body Weight; Child; Glucagon; Glucose Tolerance Test; Gonadal Dysgenesis; Growth Hormone; Humans; Insulin; Insulin Resistance; Malabsorption Syndromes; Male; Obesity; Tolbutamide

1985
[Insulin resistance in chronic liver disease: the possible role of anti-insulin factors].
    Bollettino della Societa italiana di biologia sperimentale, 1985, Oct-30, Volume: 61, Issue:10

    Topics: Adult; C-Peptide; Chronic Disease; Fatty Acids, Nonesterified; Female; Glucagon; Growth Hormone; Humans; Insulin; Insulin Antagonists; Insulin Resistance; Liver Diseases; Male; Middle Aged

1985
[Causes of insulin resistance in type 1 diabetes].
    Wiener klinische Wochenschrift, 1985, Apr-12, Volume: 97, Issue:8

    Topics: Animals; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Growth Hormone; Humans; Hydrocortisone; Insulin Antibodies; Insulin Resistance; Osmolar Concentration; Rats

1985
Assessment of tissue sensitivity to insulin in uraemic patients on long-term haemodialysis therapy.
    Diabetes research (Edinburgh, Scotland), 1985, Volume: 2, Issue:2

    Topics: Adult; Blood Glucose; C-Peptide; Constriction; Female; Glucagon; Growth Hormone; Humans; Insulin Resistance; Male; Middle Aged; Renal Dialysis; Uremia

1985
Insulin-receptor interaction in the obese-hyperglycemic mouse. A model of insulin resistance.
    The Journal of biological chemistry, 1973, Jan-10, Volume: 248, Issue:1

    Topics: Animals; Cell Fractionation; Cell Membrane; Electrophoresis, Disc; Genetics; Glucagon; Growth Hormone; Hypoglycemia; Insulin; Insulin Antibodies; Insulin Resistance; Iodine Isotopes; Isoproterenol; Liver; Mice; Mice, Inbred C57BL; Microscopy, Phase-Contrast; Obesity; Protein Binding; Proteins; Receptors, Cell Surface

1973
Decreased binding of insulin to its receptors in rats with hormone induced insulin resistance.
    Biochemical and biophysical research communications, 1973, Aug-06, Volume: 53, Issue:3

    Topics: Animals; Blood Glucose; Cell Membrane; Corticosterone; Dose-Response Relationship, Drug; Female; Glucagon; Growth Hormone; Insulin; Insulin Resistance; Iodine Isotopes; Liver; Neoplasms, Experimental; Pituitary Neoplasms; Protein Binding; Rats; Receptors, Cell Surface; Time Factors

1973
Insulin, glucagon and growth hormone in primary adult myxoedema.
    Diabetologia, 1974, Volume: 10, Issue:1

    Topics: Arginine; Blood Glucose; Female; Glucagon; Glucose Tolerance Test; Growth Hormone; Humans; Hypoglycemia; Insulin; Insulin Resistance; Male; Myxedema

1974
[Hyperglycemia and insulin resistance during glucagon infusion].
    Connecticut medicine, 1972, Volume: 36, Issue:4

    Topics: Aged; Female; Glucagon; Humans; Hyperglycemia; Injections, Intravenous; Insulin Resistance

1972
Lipoprotein and carbohydrate disorders in nephrotic syndrome and uremia.
    Revue europeenne d'etudes cliniques et biologiques. European journal of clinical and biological research, 1972, Volume: 17, Issue:1

    Topics: Adipose Tissue; Blood Glucose; Carbohydrate Metabolism; Cholesterol; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Tolerance Test; Humans; Injections, Intravenous; Insulin; Insulin Antagonists; Insulin Resistance; Kidney Failure, Chronic; Lipid Metabolism; Lipoproteins; Liver; Male; Muscles; Nephrotic Syndrome; Protein Biosynthesis; Tolbutamide; Uremia

1972
Hyperglycemic response to massive doses of commercial insulin.
    Diabetes, 1970, Volume: 19, Issue:1

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Hyperglycemia; Insulin; Insulin Resistance; Male; Rabbits

1970
Effect of enteric hormones on insulin secretion.
    Metabolism: clinical and experimental, 1970, Volume: 19, Issue:1

    Topics: Adult; Blood Glucose; Cholecystokinin; Diabetes Mellitus; Female; Glucagon; Hormones; Humans; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Male; Middle Aged; Prediabetic State; Secretin; Tolbutamide

1970
[Symposium: interrelations among hormones. 3. Spleen: effects of the digestive tract to insulin secretion (interrelation to glucagon)].
    Nihon Naibunpi Gakkai zasshi, 1970, Feb-10, Volume: 45

    Topics: Animals; Blood Glucose; Diabetes Mellitus; Digestive System Physiological Phenomena; Glucagon; Glucose Tolerance Test; Humans; In Vitro Techniques; Injections, Intravenous; Insulin; Insulin Resistance; Insulin Secretion; Rabbits

1970
[Problems of the pathogenesis and prospects of the study of diabetes mellitus in children].
    Pediatriia, 1967, Volume: 46, Issue:9

    Topics: Antibody Formation; Carbohydrate Metabolism; Child; Diabetes Mellitus, Type 1; Glucagon; Glucocorticoids; Humans; Insulin Antibodies; Insulin Resistance

1967