Page last updated: 2024-09-04

glucagon and Hyperplasia

glucagon has been researched along with Hyperplasia in 80 studies

Research

Studies (80)

Timeframe	Studies, this research(%)	All Research%
pre-1990	37 (46.25)	18.7374
1990's	6 (7.50)	18.2507
2000's	16 (20.00)	29.6817
2010's	14 (17.50)	24.3611
2020's	7 (8.75)	2.80

Authors

Authors	Studies
Casanueva-Álvarez, E; Cózar-Castellano, I; Fernández-Díaz, CM; González-Casimiro, CM; Kaestner, KH; Leissring, MA; Merino, B; Perdomo, G; Postigo-Casado, T; Quesada, I	1
Cui, X; Gu, L; Hong, T; Lin, X; Wei, R; Yang, J; Yang, K	1
Bai, X; Chen, X; Jia, J; Kang, Q; Li, M; Wong, FS; Xu, Y; Zhang, C; Zhang, XK; Zheng, J	1
Bai, X; Han, D; Jia, J; Kang, Q; Li, M; Li, Z; Wu, X; Yuan, H	1
Coulter-Parkhill, A; Dubey, V; Flatt, PR; Irwin, N; Lafferty, R; Moffett, C; O'Harte, F; Tanday, N; Vishal, K	1
Klöppel, G; Sipos, B	1
de Herder, WW; Klöppel, G	1
Anguiano, G; Cavino, K; Chen, S; Gromada, J; Hamid, R; Huang, Z; Kim, J; Lee, J; Li, WH; Liu, Q; Murphy, AJ; Na, E; Okamoto, H; Unger, R; Xin, Y; Xu, Y; Yancopoulos, GD; Zambrowicz, B	1
Clifton-Bligh, RJ; Gild, ML; Gill, AJ; Samra, J; Tacon, L; Tsang, V	1
Gilbert, RE; Jin, T; Thai, K; Woo, M; Zhang, Y	1
Cavino, K; Dominguez Gutierrez, G; Gromada, J; Kim, J; Kloeppel, G; Okamoto, H; Sipos, B; Sung, B; Xin, Y	1
Hayashi, Y; Itoh, M; Murata, Y; Takagishi, Y; Xu, S	1
Betts, CJ; Bickerton, S; Bigley, AL; Brocklehurst, SR; Jenkins, RP; Jones, HB; Morgan, D; Reens, J; Smith, DM; Whalley, NM	1
Bang, S; Choi, H; Kang, CM; Kang, H; Kim, HG; Kim, S; Lee, HW; Lim, TS	1
Barrande, G; Bertherat, J; Desailloud, R; Duparc, C; Gobet, F; Groussin, L; Lefebvre, H; Louiset, E; Prévost, G; Reznik, Y	1
Anlauf, M; Boehm, BO; Buch, S; Couvelard, A; Hammel, P; Hampe, J; Henopp, T; Höbling, W; Hoffmeister, M; Klöppel, G; Lieb, W; Sipos, B; Sperveslage, J; Weber, A	1
Cavino, K; Gromada, J; Harp, J; Kim, S; Krumm, E; Murphy, AJ; Na, E; Okamoto, H; Stevis, PE; Yancopoulos, GD	1
Chen, CR; Dhall, D; Nissen, NN; Yu, R; Zhou, C	1
Atangan, L; Bi, V; Boone, T; Gu, W; Hill, D; Hu, S; Komorowski, R; Lindberg, RA; Shen, Y; Sivits, G; Véniant, MM; Vonderfecht, S; Winters, KA; Yan, H; Yang, J	1
Hayashi, Y; Ito, R; Mizoguchi, H; Murata, Y; Sun, XY; Watanabe, C; Yamamoto, M; Yamamoto, S	1
Chintinne, M; Declercq, J; Di Pietro, C; Ectors, N; Gysemans, C; Heimberg, H; Kumar, A; Lemaire, K; Mathieu, C; Pipeleers, D; Schraenen, A; Schuit, FC; Van De Casteele, M; Van de Ven, WJ; Van Lommel, L; Verfaillie, CM	1
Alison, MR; El-Bahrawy, ME; Fritsch, K; Guppy, NJ; Jeffery, RE; Kocher, HM; Otto, WR; Poulsom, R; Qureshi, YA; Wright, NA	1
Ali, S; Charron, MJ; Dai, C; de Chavez, V; Dean, ED; Drucker, DJ; Longuet, C; McGuinness, I; Powers, AC; Robledo, AM; Vuguin, PM	1
Habener, JF; Stanojevic, V	1
Schiel, KA	1
Charron, MJ; Cui, L; Dichmann, DS; Du, XQ; Fledelius, C; Gelling, RW; Holst, JJ; Huang, H; Jelicks, LA; Johansen, PB; Nishimura, E; Obici, S; Romer, J; Rossetti, L; Serup, P; Tang, B	1
Büchler, MW; Friess, H; Kated, H; Martignoni, ME; Nitzsche, EU; Schirp, U; Stiegler, M; Zimmermann, A	1
Cummings, DE	1
Charron, MJ; Cui, L; Gelling, RW; Guz, Y; Kedees, MH; Nejathaim, M; Teitelman, G; Vuguin, PM	1
Alison, MR; Sarraf, CE; Shen, CN; Slack, JM; Tosh, D	1
Függer, R; Funovics, J; Schulz, F; Ulrich, W; Zöch, G	1
Doull, V; Friesen, S; Tomita, T; Visser, P	1
Allo, MD; Eckhauser, FE; Lloyd, RV; Mervak, T; Nishiyama, RH; Strodel, WE; Talpos, G; Thompson, NW; Vinik, AI	1
Fujita, T; Hirata, Y; Kakita, T; Matsukura, S; Sueoka, S; Yokota, M; Yoshimi, H	1
Mahler, RJ	2
von Dorsche, HH; Ziegler, M	1
Brennan, MD; Carpenter, AM; Edis, AJ; Rubenstein, AH; Service, FJ	1
Atkins, TW; Bailey, CJ; Flatt, PR	1
Bloom, SR; Fuller, CR; Ghatei, MA; Hoyt, EC; Lund, PK; Ulshen, MH	1
Contis, J; Kaminski, DL; Li, AP; Solomon, H	1
Bellini, F; Ianni, L; Lanzillotti, R; Mannelli, M; Natali, A; Pupilli, C	1
Bosch, F; Casellas, A; Devedjian, JC; George, M; Gros, L; Pelegrín, M; Pujol, A; Visa, J	1
Ashok, S; Deepa, R; Govindarajan, M; Mohan, V; Pitchumoni, CS	1
Bucchini, D; Cordonnier, N; Desbois, P; Duvillié, B; Jackerott, M; Jami, J; Joshi, RL; Lamotte, L; Leroux, L	1
Cincotta, AH; Jetton, TL; Liang, Y	1
Allen, MR; Andrews, KM; McNeish, JD; Parker, JC; Stock, JL	1
Akbar, MS; Steiner, DF; Swift, HH; Webb, GC; Zhao, C	1
Bucchini, D; Chrones, T; Currie, C; Duvillié, B; Hill, DJ; Jami, J; Joshi, RL	1
Ammann, R; Hedinger, C; Säuberli, H; Woodtli, W; Zimmermann, K	1
Welbourn, RB	1
Amherdt, M; Baetens, D; Malaisse-Lagae, F; Orci, L; Ravazzola, M; Rufener, C; Studer, P; Unger, RH	1
Larsson, LI	1
Bommer, G; Commandeur, G; Heitz, P; Klöppel, G	1
Thomas, M; Vigouroux, N	1
Benichou, J; Francavilla, A; Jones, AF; Porter, KA; Starzl, TE	1
Andreani, D; Natoli, C; Tamburrano, G; Tamburrano, S	1
Schwartz, TW	1
Accary, JP; Mignon, M; Soulé, JC	1
Chertow, BS; Fariss, BL; Schikman, CH	1
Aurbach, GD; Brown, EM; Marx, SJ; Spiegel, AM	1
Farouk, M; McVey, DC; Meyers, WC; Vigna, SR	1
Arai, T; Oki, Y; Sasaki, M; Usui, T	1
Hisaoka, M; Horie, A	1
Goudswaard, WB; Houthoff, HJ; Koudstaal, J; Zwierstra, RP	1
Andreu, M; Greaves, P; Spencer, AJ	1
Grizzle, WE; Herrera, GA; Kheir, SM; Lee, I; Omura, EF	1
Ambrosius, H; Fuchs, U; von Dorsche, HH; Ziegler, M	1
Domingo, J; Estadella, MD; Pujol, MJ	1
Fujinaka, S; Hamajo, T; Kobashi, K; Onoe, K; Yamamoto, T	1
Chayoth, R; Epstein, SM; Field, JB	1
Croisier, JC; Lehy, T; Zeitoun, P	1
Hunter, DJ; Isles, TE	1
Forsham, PH; Grodsky, GM; Karam, JH	1
Barnes, GL	1
Misugi, K; Misugi, N; Smith, B; Sotos, J	1
Max, MH; Price, JB; Takeshige, K; Voorhees, AB	1
Cummings, D; Harper, PV; Lawrence, AM; Paloyan, D; Paloyan, E; Straus, FH	1
Chivu, V; Lupulescu, A; Petrovici, A	1
Horita, M; Ishimatsu, T; Iwashita, K; Kodama, M; Ono, J; Oribe, Y; Sato, Y; Shigematsu, S; Shimoyama, N; Takaki, R	1

Reviews

10 review(s) available for glucagon and Hyperplasia

Article	Year
Glucagon cell hyperplasia and neoplasia: a recently recognized endocrine receptor disease. Endocrine-related cancer, 2023, 08-01, Volume: 30, Issue:8 Topics: Animals; Glucagon; Glucagon-Secreting Cells; Humans; Hyperplasia; Mice; Neoplasms; Receptors, Glucagon	2023
One hundred years after the discovery of insulin and glucagon: the history of tumors and hyperplasias that hypersecrete these hormones. Endocrine-related cancer, 2023, 09-01, Volume: 30, Issue:9 Topics: Animals; Dogs; Glucagon; Hyperplasia; Insulin; Insulinoma; Pancreatic Neoplasms	2023
Alpha cells come of age. Trends in endocrinology and metabolism: TEM, 2013, Volume: 24, Issue:3 Topics: Animals; Cell Dedifferentiation; Cell Lineage; Cell Transdifferentiation; Diabetes Mellitus, Experimental; Enteroendocrine Cells; Epithelial-Mesenchymal Transition; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Homeodomain Proteins; Humans; Hyperplasia; Insulin-Secreting Cells; Islets of Langerhans; Mice; Paired Box Transcription Factors; Proprotein Convertase 1; Signal Transduction; Transcription Factors	2013
The relationship between the hyperplastic pancreatic islet and insulin insensitivity in obesity. Acta diabetologica latina, 1981, Volume: 18, Issue:1 Topics: Adipose Tissue; Alloxan; Animals; Glucagon; Glucose; Humans; Hyperplasia; Insulin; Insulin Resistance; Islets of Langerhans; Liver; Mice; Mice, Obese; Microscopy, Electron; Muscles; Obesity; Receptor, Insulin; Streptozocin	1981
Apudomas of the gut. American journal of surgery, 1977, Volume: 133, Issue:1 Topics: Acute Kidney Injury; Adenoma, Islet Cell; Adult; Amines; Carboxy-Lyases; Dehydration; Endocrine Glands; Fluorescent Antibody Technique; Gastrins; Glucagon; Humans; Hyperplasia; Intestinal Neoplasms; Intestinal Secretions; Intestines; Male; Multiple Endocrine Neoplasia; Neurosecretory Systems; Pancreas; Paraneoplastic Endocrine Syndromes; Peptides; Zollinger-Ellison Syndrome	1977
[Hormones of the digestive system. II. Pathology]. Medecine & chirurgie digestives, 1978, Volume: 7, Issue:4 Topics: Acute Kidney Injury; Adenoma, Islet Cell; Adolescent; Adult; Aged; Carcinoid Tumor; Child; Dehydration; Female; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Hormones; Gastrointestinal Neoplasms; Glucagon; Humans; Hyperplasia; Hypokalemia; Insulin; Insulin Secretion; Male; Middle Aged; Pancreatic Neoplasms; Paraneoplastic Endocrine Syndromes; Precancerous Conditions; Serotonin; Somatostatin; Syndrome; Vasoactive Intestinal Peptide; Zollinger-Ellison Syndrome	1978
[Pathophysiological significance of hypergastrinaemia in man (author's transl)]. Gastroenterologie clinique et biologique, 1977, Volume: 1, Issue:2 Topics: Anemia, Pernicious; Calcium; Dietary Proteins; Duodenal Ulcer; Gastric Juice; Gastrins; Gastritis; Glucagon; Humans; Hyperplasia; Intestine, Small; Kidney Failure, Chronic; Pyloric Antrum; Pyloric Stenosis; Secretin; Stomach Neoplasms; Stomach Ulcer; Vagotomy; Zollinger-Ellison Syndrome	1977
[Hypoglycemia and its countermeasures]. Nihon rinsho. Japanese journal of clinical medicine, 1969, Volume: 27, Issue:8 Topics: Acute Disease; Adenoma, Islet Cell; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Animals; Blood Glucose; Cortisone; Diazoxide; Ethanol; Female; Gastrectomy; Glucagon; Growth Hormone; Humans; Hyperplasia; Hypoglycemia; Hypoglycemic Agents; Hypophysectomy; Hypothyroidism; Insulin; Insulin Secretion; Liver Diseases; Male; Middle Aged; Osteosarcoma; Rats; Xylitol	1969
The pathogenesis of pancreatic islet cell hyperplasia and insulin insensitivity in obesity. Advances in metabolic disorders, 1974, Volume: 7, Issue:0 Topics: Adrenal Cortex; Amino Acids; Biological Transport, Active; Epinephrine; Fatty Acids, Nonesterified; Genes; Glucagon; Glucose; Growth Hormone; Humans; Hydrocortisone; Hyperplasia; Hypothalamus; Insulin; Islets of Langerhans; Obesity	1974
Insulin secretion in obesity: pseudodiabetes? The American journal of clinical nutrition, 1968, Volume: 21, Issue:12 Topics: Age Factors; Animals; Diabetes Mellitus; Glucagon; Glucose; Humans; Hyperplasia; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans	1968

Other Studies

70 other study(ies) available for glucagon and Hyperplasia

Article	Year
Insulin-degrading enzyme ablation in mouse pancreatic alpha cells triggers cell proliferation, hyperplasia and glucagon secretion dysregulation. Diabetologia, 2022, Volume: 65, Issue:8 Topics: alpha-Synuclein; Animals; Cell Proliferation; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Secreting Cells; Hyperplasia; Insulin; Insulin-Secreting Cells; Insulysin; Mice	2022
γ-aminobutyric acid modulates α-cell hyperplasia but not β-cell regeneration induced by glucagon receptor antagonism in type 1 diabetic mice. Acta diabetologica, 2023, Volume: 60, Issue:1 Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; gamma-Aminobutyric Acid; Glucagon; Hyperplasia; Insulin; Insulin-Secreting Cells; Mice; Receptors, Glucagon; Regeneration	2023
Disruption of the glucagon receptor increases glucagon expression beyond α-cell hyperplasia in zebrafish. The Journal of biological chemistry, 2022, Volume: 298, Issue:12 Topics: Animals; Glucagon; Hyperplasia; Receptors, Glucagon; RNA, Messenger; Zebrafish	2022
Crispr-Cas9 mediated complete deletion of glucagon receptor in mice display hyperglucagonemia and α-cell hyperplasia. Biochemical and biophysical research communications, 2023, 02-05, Volume: 643 Topics: Animals; CRISPR-Cas Systems; Glucagon; Hyperplasia; Mice; Mice, Knockout; Receptors, Glucagon	2023
The glucagon receptor antagonist desHis Molecular and cellular endocrinology, 2023, 06-15, Volume: 570 Topics: Animals; Blood Glucose; Glucagon; Humans; Hyperplasia; Insulin; Mice; Receptors, Glucagon	2023
Amino Acid Transporter Slc38a5 Controls Glucagon Receptor Inhibition-Induced Pancreatic α Cell Hyperplasia in Mice. Cell metabolism, 2017, Jun-06, Volume: 25, Issue:6 Topics: Amino Acid Transport Systems, Neutral; Animals; Glucagon; Glucagon-Secreting Cells; Hyperplasia; Male; Mice; Mice, Inbred ICR; Mice, Knockout; Receptors, Glucagon; Signal Transduction	2017
Hypercalcemia in Glucagon Cell Hyperplasia and Neoplasia (Mahvash Syndrome): A New Association. The Journal of clinical endocrinology and metabolism, 2018, 09-01, Volume: 103, Issue:9 Topics: Carcinoma, Neuroendocrine; Glucagon; Glucagon-Secreting Cells; Humans; Hypercalcemia; Hyperplasia; Lymphatic Metastasis; Male; Middle Aged; Mutation, Missense; Pancreatic Neoplasms; Paraneoplastic Syndromes; Receptors, Glucagon; Syndrome	2018
SIRT1 activation attenuates α cell hyperplasia, hyperglucagonaemia and hyperglycaemia in STZ-diabetic mice. Scientific reports, 2018, 09-18, Volume: 8, Issue:1 Topics: Anilides; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Hyperglycemia; Hyperplasia; Insulin; Male; Mice; Sirtuin 1; Thiazoles	2018
Increased SLC38A4 Amino Acid Transporter Expression in Human Pancreatic α-Cells After Glucagon Receptor Inhibition. Endocrinology, 2019, 05-01, Volume: 160, Issue:5 Topics: Adult; Amino Acid Transport System A; Animals; Cell Proliferation; Female; Glucagon; Glucagon-Secreting Cells; Humans; Hyperplasia; Islets of Langerhans Transplantation; Male; Mice; Middle Aged; Receptors, Glucagon; Signal Transduction; Transplantation, Heterologous	2019
Aristaless-related homeobox plays a key role in hyperplasia of the pancreas islet α-like cells in mice deficient in proglucagon-derived peptides. PloS one, 2013, Volume: 8, Issue:5 Topics: Animals; Blood Glucose; Body Weight; Female; Gene Expression; Glucagon; Green Fluorescent Proteins; Homeodomain Proteins; Hyperplasia; Immunohistochemistry; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microscopy, Fluorescence; Mutation; Peptides; Proglucagon; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors	2013
Islets of Langerhans from prohormone convertase-2 knockout mice show α-cell hyperplasia and tumorigenesis with elevated α-cell neogenesis. International journal of experimental pathology, 2014, Volume: 95, Issue:1 Topics: Adenoma; Animals; Carcinogenesis; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Epithelial-Mesenchymal Transition; Female; Glucagon; Glucagon-Secreting Cells; Hyperplasia; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pancreatic Neoplasms; Proprotein Convertase 2	2014
[A case of alpha-cell nesidioblastosis and hyperplasia with multiple glucagon-producing endocrine cell tumor of the pancreas]. The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2014, Volume: 63, Issue:4 Topics: Adult; Chromogranin A; Female; Glucagon; Glucagon-Secreting Cells; Humans; Hyperplasia; Islets of Langerhans; Nesidioblastosis; Neuroendocrine Tumors; Pancreas; Tomography, X-Ray Computed; Ultrasonography	2014
Abnormal Sensitivity to Glucagon and Related Peptides in Primary Adrenal Cushing's Syndrome. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2014, Volume: 46, Issue:12 Topics: Adrenal Glands; Adrenocortical Adenoma; Adult; Aged; Cushing Syndrome; Female; Glucagon; Humans; Hydrocortisone; Hyperplasia; Immunohistochemistry; Kinetics; Male; Middle Aged; Peptides; Receptors, Glucagon; Young Adult	2014
Glucagon cell hyperplasia and neoplasia with and without glucagon receptor mutations. The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:5 Topics: Adult; Aged; Female; Glucagon; Glucagon-Secreting Cells; Humans; Hyperplasia; Male; Middle Aged; Mutation; Pancreas; Pancreatic Neoplasms; Receptors, Glucagon	2015
Angptl4 does not control hyperglucagonemia or α-cell hyperplasia following glucagon receptor inhibition. Proceedings of the National Academy of Sciences of the United States of America, 2017, 03-07, Volume: 114, Issue:10 Topics: Angiopoietin-Like Protein 4; Animals; Blood Glucose; Cell Proliferation; Glucagon; Glucagon-Secreting Cells; Humans; Hyperplasia; Lipid Metabolism; Lipoproteins; Liver; Mice; Mice, Knockout; Receptors, Glucagon; Signal Transduction; Triglycerides	2017
Homozygous P86S mutation of the human glucagon receptor is associated with hyperglucagonemia, alpha cell hyperplasia, and islet cell tumor. Pancreas, 2009, Volume: 38, Issue:8 Topics: Aged; Amino Acid Sequence; Base Sequence; Carcinoma, Islet Cell; Cell Line; Cell Membrane; DNA Mutational Analysis; Female; Fluorescent Antibody Technique; Glucagon; Glucagon-Secreting Cells; Green Fluorescent Proteins; Homozygote; Humans; Hyperplasia; Immunoblotting; Male; Molecular Sequence Data; Mutation, Missense; Pancreatic Neoplasms; Pedigree; Receptors, Glucagon; Transfection	2009
Long-term inhibition of the glucagon receptor with a monoclonal antibody in mice causes sustained improvement in glycemic control, with reversible alpha-cell hyperplasia and hyperglucagonemia. The Journal of pharmacology and experimental therapeutics, 2009, Volume: 331, Issue:3 Topics: Animals; Antibodies, Monoclonal; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Glucagon-Secreting Cells; Glucose; Hyperglycemia; Hyperplasia; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Mice; Mice, Inbred C57BL; Obesity; Receptors, Glucagon; Tachyphylaxis	2009
Mice deficient for glucagon gene-derived peptides display normoglycemia and hyperplasia of islet {alpha}-cells but not of intestinal L-cells. Molecular endocrinology (Baltimore, Md.), 2009, Volume: 23, Issue:12 Topics: Animals; Enteroendocrine Cells; Flow Cytometry; Gene Knock-In Techniques; Genotype; Glucagon; Glucagon-Secreting Cells; Hyperplasia; Immunoenzyme Techniques; Immunohistochemistry; Islets of Langerhans; Mice	2009
Pdx1- and Ngn3-Cre-mediated PLAG1 expression in the pancreas leads to endocrine hormone imbalances that affect glucose metabolism. Cell transplantation, 2011, Volume: 20, Issue:8 Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Proliferation; DNA-Binding Proteins; Glucagon; Glucose; Glucose Tolerance Test; Homeodomain Proteins; Homeostasis; Hyperplasia; Hypoglycemia; Insulin; Integrases; Islets of Langerhans; Islets of Langerhans Transplantation; Mice; Mice, Transgenic; Nerve Tissue Proteins; Organ Size; Pancreatic Hormones; Somatostatin; Time Factors; Trans-Activators	2011
Trefoil factor family peptides in normal and diseased human pancreas. Pancreas, 2012, Volume: 41, Issue:6 Topics: Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation; Glucagon; Humans; Hyperplasia; Immunohistochemistry; In Situ Hybridization; Insulin; Ki-67 Antigen; Mucin 5AC; Pancreas; Pancreatic Diseases; Pancreatic Neoplasms; Pancreatitis; Peptides; RNA, Messenger; Trefoil Factor-2; Trefoil Factor-3	2012
Liver-specific disruption of the murine glucagon receptor produces α-cell hyperplasia: evidence for a circulating α-cell growth factor. Diabetes, 2013, Volume: 62, Issue:4 Topics: Animals; Blood Glucose; Female; Glucagon; Glucagon-Secreting Cells; Glucose; Hepatocytes; Hyperplasia; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Islets of Langerhans; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Glucagon; Signal Transduction	2013
An etiologic model proposing that non-insulin-dependent diabetes mellitus is chronic hypoxic stress hyperglycemia. Medical hypotheses, 2002, Volume: 59, Issue:5 Topics: Anemia; Arteriosclerosis; Arthritis, Rheumatoid; Blood Glucose; Brain; Catecholamines; Diabetes Mellitus, Type 2; Edema; Endothelins; Endothelium, Vascular; Ephedrine; Glucagon; Hemorheology; Hydrocortisone; Hyperglycemia; Hyperplasia; Hypothalamo-Hypophyseal System; Hypoxia; Mitosis; Models, Biological; Muscle, Smooth, Vascular; Pituitary-Adrenal System; Sympathetic Nervous System; Vasodilation	2002
Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice. Proceedings of the National Academy of Sciences of the United States of America, 2003, Feb-04, Volume: 100, Issue:3 Topics: Animals; Blood Glucose; Body Weight; Calorimetry; Cell Division; Cyclic AMP; Epididymis; Epinephrine; Glucagon; Glucose; Hormones; Hyperplasia; Immunohistochemistry; Insulin; Islets of Langerhans; Liver; Male; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Phenotype; Receptors, Glucagon; Time Factors	2003
Nesidioblastosis with glucagon-reactive islet cell hyperplasia: a case report. Pancreas, 2003, Volume: 26, Issue:4 Topics: Glucagon; Humans; Hyperplasia; Immunohistochemistry; Insulin; Islets of Langerhans; Male; Middle Aged; Pancreatic Diseases	2003
Gastric bypass and nesidioblastosis--too much of a good thing for islets? The New England journal of medicine, 2005, Jul-21, Volume: 353, Issue:3 Topics: Adenosine Deaminase Inhibitors; Dipeptidyl Peptidase 4; Gastric Bypass; Glucagon; Glucagon-Like Peptide 1; Glycoproteins; Humans; Hyperinsulinism; Hyperplasia; Hypoglycemia; Islets of Langerhans; Nesidioblastosis; Obesity; Peptide Fragments; Postoperative Complications; Protein Precursors; Signal Transduction	2005
Ablation of the glucagon receptor gene increases fetal lethality and produces alterations in islet development and maturation. Endocrinology, 2006, Volume: 147, Issue:9 Topics: Animals; Blood Glucose; Cell Differentiation; Cell Division; Feedback, Physiological; Female; Fetal Death; Fetal Development; Gene Deletion; Genotype; Glucagon; Hyperplasia; Insulin; Islets of Langerhans; Male; Mice; Mice, Knockout; Microscopy, Confocal; Pregnancy; Receptors, Glucagon; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction	2006
Copper deprivation in rats induces islet hyperplasia and hepatic metaplasia in the pancreas. Biology of the cell, 2007, Volume: 99, Issue:1 Topics: Animals; Copper; Glucagon; Glycogen; Hepatocytes; Hyperplasia; Insulin; Islets of Langerhans; Liver; Male; Metaplasia; Rats; Rats, Wistar	2007
[Tumors of the endocrine pancreas]. Zentralblatt fur Chirurgie, 1984, Volume: 109, Issue:23 Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Child; Female; Follow-Up Studies; Gastrectomy; Gastrins; Glucagon; Humans; Hyperplasia; Insulin; Insulinoma; Islets of Langerhans; Male; Middle Aged; Pancreatectomy; Pancreatic Neoplasms; Postoperative Complications; Stomach Neoplasms; Zollinger-Ellison Syndrome	1984
Cortisone-induced islet cell hyperplasia in hamsters. Virchows Archiv. B, Cell pathology including molecular pathology, 1984, Volume: 45, Issue:1 Topics: Animals; Blood Glucose; Cortisone; Cricetinae; Female; Glucagon; Hyperplasia; Insulin; Islets of Langerhans; Mesocricetus; Pancreas; Pancreatic Polypeptide; Somatostatin; Time Factors	1984
MEN I pancreas: a histological and immunohistochemical study. World journal of surgery, 1984, Volume: 8, Issue:4 Topics: Adenoma, Islet Cell; Adult; Female; Gastrins; Glucagon; Humans; Hyperplasia; Islets of Langerhans; Male; Middle Aged; Multiple Endocrine Neoplasia; Pancreatic Neoplasms; Pancreatic Polypeptide; Phosphopyruvate Hydratase; Serotonin; Somatostatin; Staining and Labeling; Vasoactive Intestinal Peptide; Zollinger-Ellison Syndrome	1984
Multiple hormone receptors in the adenylate cyclase of human adrenocortical tumors. Cancer research, 1980, Volume: 40, Issue:10 Topics: Adenoma; Adenylyl Cyclases; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Cushing Syndrome; Cyclic AMP; Glucagon; Humans; Hyperplasia; Prostaglandins E; Receptors, Cell Surface	1980
[A-cell-hyperplasia of islets of Langerhans on rabbits after immunisation with glucagon (author's transl)]. Acta histochemica, 1981, Volume: 68, Issue:2 Topics: Animals; Antibody Formation; Fluorescent Antibody Technique; Glucagon; Hyperplasia; Islets of Langerhans; Rabbits	1981
Diagnosis of pancreatic islet hyperplasia causing hypoglycemia in a patient with portacaval anastomosis. The American journal of medicine, 1980, Volume: 68, Issue:6 Topics: Blood Chemical Analysis; Blood Glucose; C-Peptide; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperplasia; Hypoglycemia; Insulin; Islets of Langerhans; Middle Aged; Portacaval Shunt, Surgical; Tolbutamide	1980
Influence of genetic background and age on the expression of the obese hyperglycaemic syndrome in Aston ob/ob mice. International journal of obesity, 1982, Volume: 6, Issue:1 Topics: Aging; Animals; Female; Glucagon; Hyperglycemia; Hyperplasia; Insulin; Islets of Langerhans; Male; Mice; Mice, Obese	1982
Increased ileal proglucagon expression after jejunectomy is not suppressed by inhibition of bowel growth. Digestive diseases and sciences, 1996, Volume: 41, Issue:4 Topics: Adaptation, Physiological; Animals; Blotting, Northern; Eflornithine; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hyperplasia; Ileum; Intestinal Mucosa; Jejunum; Male; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Peptide Fragments; Proglucagon; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger	1996
The effect of prostanoids on hepatic bile flow in dogs with normal liver and bile duct cell hyperplasia. Prostaglandins, leukotrienes, and essential fatty acids, 1996, Volume: 54, Issue:4 Topics: 1-Naphthylisothiocyanate; Animals; Bile; Bile Acids and Salts; Bile Duct Diseases; Cholestasis; Common Bile Duct; Dinoprostone; Dogs; Epoprostenol; Glucagon; Hyperplasia; Secretin	1996
Glucocorticoid-phenylethanolamine-N-methyltransferase interactions in humans. Advances in pharmacology (San Diego, Calif.), 1998, Volume: 42 Topics: Adenoma; Adrenal Cortex Diseases; Adrenal Gland Neoplasms; Adrenal Medulla; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Epinephrine; Female; Glucagon; Humans; Hydrocortisone; Hyperplasia; Male; Norepinephrine; Phenylethanolamine N-Methyltransferase	1998
Transgenic mice overexpressing insulin-like growth factor-II in beta cells develop type 2 diabetes. The Journal of clinical investigation, 2000, Volume: 105, Issue:6 Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Fats; Fatty Liver; Gene Expression; Glucagon; Glucose; Glucose Tolerance Test; Hyperinsulinism; Hyperplasia; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Islets of Langerhans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Obesity; Promoter Regions, Genetic; Rats; Recombinant Fusion Proteins; RNA, Messenger	2000
Histopathology and immunohistochemistry of pancreatic islets in fibrocalculous pancreatic diabetes. Diabetes research and clinical practice, 2001, Volume: 51, Issue:1 Topics: Adolescent; Adult; Atrophy; Biopsy; Blood Glucose; Chronic Disease; Diabetes Mellitus; Female; Gastrins; Glucagon; Humans; Hyperplasia; Immunohistochemistry; Insulin; Islets of Langerhans; Male; Middle Aged; Pancreas; Pancreatic Ducts; Pancreatic Polypeptide; Pancreatitis; Vasoactive Intestinal Peptide	2001
Compensatory responses in mice carrying a null mutation for Ins1 or Ins2. Diabetes, 2001, Volume: 50 Suppl 1 Topics: Animals; Blotting, Western; Cell Count; Female; Gene Expression; Glucagon; Hyperplasia; Immunohistochemistry; Insulin; Islets of Langerhans; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Mutation; Pancreatic Polypeptide; Proinsulin; Reverse Transcriptase Polymerase Chain Reaction; RNA; Somatostatin	2001
Systemic treatment with sympatholytic dopamine agonists improves aberrant beta-cell hyperplasia and GLUT2, glucokinase, and insulin immunoreactive levels in ob/ob mice. Metabolism: clinical and experimental, 2001, Volume: 50, Issue:11 Topics: Animals; Apoptosis; Cell Division; DNA; Dopamine Agonists; Female; Glucagon; Glucokinase; Glucose Transporter Type 2; Hyperplasia; Immunohistochemistry; In Situ Nick-End Labeling; Insulin; Islets of Langerhans; Mice; Mice, Inbred C57BL; Mice, Obese; Monosaccharide Transport Proteins; Somatostatin; Sympatholytics	2001
Glycemic control in mice with targeted disruption of the glucagon receptor gene. Biochemical and biophysical research communications, 2002, Jan-18, Volume: 290, Issue:2 Topics: Animals; Blood Glucose; Cholesterol; Gene Targeting; Glucagon; Glucose; Glucose Tolerance Test; Hyperplasia; Insulin; Metabolism, Inborn Errors; Mice; Mice, Knockout; Organ Size; Pancreas; Phenotype; Receptors, Glucagon; Triglycerides	2002
Glucagon replacement via micro-osmotic pump corrects hypoglycemia and alpha-cell hyperplasia in prohormone convertase 2 knockout mice. Diabetes, 2002, Volume: 51, Issue:2 Topics: Animals; Apoptosis; Blood Glucose; Gene Expression; Glucagon; Hyperplasia; Hypoglycemia; Islets of Langerhans; Liver; Mice; Mice, Knockout; Proprotein Convertase 2; Subtilisins	2002
Increased islet cell proliferation, decreased apoptosis, and greater vascularization leading to beta-cell hyperplasia in mutant mice lacking insulin. Endocrinology, 2002, Volume: 143, Issue:4 Topics: Animals; Apoptosis; Body Weight; Cell Division; Embryonic and Fetal Development; Endothelial Growth Factors; Glucagon; Hyperplasia; Immunohistochemistry; Insulin; Insulin-Like Growth Factor II; Islets of Langerhans; Lymphokines; Mice; Mice, Knockout; Neovascularization, Physiologic; Proliferating Cell Nuclear Antigen; Regional Blood Flow; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2002
[Glucagon producing adenomatosis of Islands of Langerhans with polyendocrine symptoms]. Schweizerische medizinische Wochenschrift, 1976, May-29, Volume: 106, Issue:22 Topics: Adipose Tissue; Adrenal Cortex; Adrenal Glands; Adult; Calcinosis; Cholecystectomy; Cushing Syndrome; Diabetes Complications; Gastrins; Glucagon; Humans; Hyperplasia; Islets of Langerhans; Male; Multiple Endocrine Neoplasia; Necrosis; Obesity; Pancreas; Zollinger-Ellison Syndrome	1976
Hypertrophy and hyperplasia of somatostatin-containing D-cells in diabetes. Proceedings of the National Academy of Sciences of the United States of America, 1976, Volume: 73, Issue:4 Topics: Adult; Animals; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hyperplasia; Hypertrophy; Insulin; Islets of Langerhans; Male; Rats; Somatostatin; Streptozocin	1976
Two distinct types of islet abnormalities associated with endocrine pancreatic tumours. Virchows Archiv. A, Pathological anatomy and histology, 1977, Nov-25, Volume: 376, Issue:3 Topics: Gastrins; Glucagon; Growth Hormone-Releasing Hormone; Humans; Hyperplasia; Insulin; Islets of Langerhans; Pancreatic Neoplasms; Peptides	1977
The endocrine pancreas in chronic pancreatitis. Immunocytochemical and ultrastructural studies. Virchows Archiv. A, Pathological anatomy and histology, 1978, Feb-10, Volume: 377, Issue:2 Topics: Adult; Aged; Chronic Disease; Female; Glucagon; Humans; Hyperplasia; Insulin; Islets of Langerhans; Male; Microscopy, Electron; Middle Aged; Pancreas; Pancreatitis; Somatostatin	1978
Liver regeneration in dogs: morphologic and chemical changes. The Journal of surgical research, 1978, Volume: 25, Issue:5 Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Dogs; Glucagon; Hepatectomy; Hyperplasia; Hypertrophy; Insulin; Liver; Liver Regeneration	1978
[The insulinomas]. Minerva medica, 1979, Jun-16, Volume: 70, Issue:28 Topics: Adenoma, Islet Cell; Diazoxide; Glucagon; Humans; Hyperplasia; Insulin; Insulin Secretion; Pancreatic Diseases; Pancreatic Neoplasms; Tolbutamide	1979
Pancreatic-polypeptide (PP) and endocrine tumours of the pancreas. Scandinavian journal of gastroenterology. Supplement, 1979, Volume: 53 Topics: Acute Kidney Injury; Adenoma, Islet Cell; Dehydration; Gastrins; Glucagon; Humans; Hyperplasia; Molecular Weight; Pancreas; Pancreatic Neoplasms; Pancreatic Polypeptide; Syndrome; Zollinger-Ellison Syndrome	1979
Paradoxical enhancement of tolbutamide-induced insulin release by diazoxide in a patient with islet cell hyperplasia. Acta paediatrica Scandinavica, 1978, Volume: 67, Issue:5 Topics: Blood Glucose; Child; Diazoxide; Glucagon; Glucose Tolerance Test; Humans; Hyperplasia; Hypoglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Male; Pancreatic Diseases; Propranolol; Tolbutamide	1978
Family studies in patients with primary parathyroid hyperplasia. The American journal of medicine, 1977, Volume: 62, Issue:5 Topics: Adolescent; Adult; Aged; Calcium; Child; Female; Gastrins; Glucagon; Humans; Hypercalcemia; Hyperplasia; Male; Middle Aged; Neoplasms, Multiple Primary; Parathyroid Glands; Parathyroid Hormone; Parathyroid Neoplasms; Pedigree; Prolactin	1977
Localization and characterization of secretin binding sites expressed by rat bile duct epithelium. Gastroenterology, 1992, Volume: 102, Issue:3 Topics: Animals; Autoradiography; Bile Ducts; Binding Sites; Binding, Competitive; Cholecystokinin; Dose-Response Relationship, Drug; Epithelium; Gastric Inhibitory Polypeptide; Glucagon; Growth Hormone-Releasing Hormone; Hyperplasia; Liver; Male; Rats; Rats, Inbred Strains; Receptors, G-Protein-Coupled; Receptors, Gastrointestinal Hormone; Secretin; Vasoactive Intestinal Peptide	1992
Immunohistochemical, ultrastructural, and hormonal studies on the endocrine pancreas of voles (Microtus arvalis) with monosodium aspartate-induced diabetes. Veterinary pathology, 1991, Volume: 28, Issue:6 Topics: Animals; Arvicolinae; Aspartic Acid; Blood Glucose; Cytoplasmic Granules; Diabetes Mellitus, Experimental; Female; Glucagon; Hyperplasia; Hypertrophy; Immunohistochemistry; Insulin; Islets of Langerhans; Male; Microscopy, Electron; Rodent Diseases; Somatostatin	1991
Unusual proliferation of the pancreatic endocrine cells in adults, suggestive of islet cell metaplasia. Journal of UOEH, 1990, Dec-01, Volume: 12, Issue:4 Topics: Carcinoma, Squamous Cell; Cell Division; Glucagon; Humans; Hyperplasia; Immunohistochemistry; Insulin; Islets of Langerhans; Lung Neoplasms; Male; Metaplasia; Middle Aged; Multiple Myeloma; Pancreatic Polypeptide; Somatostatin	1990
Nesidioblastosis and endocrine hyperplasia of the pancreas: a secondary phenomenon. Human pathology, 1986, Volume: 17, Issue:1 Topics: Adult; Aged; Child, Preschool; Glucagon; Humans; Hyperinsulinism; Hyperplasia; Infant; Infant, Newborn; Insulin; Insulinoma; Islets of Langerhans; Middle Aged; Pancreas; Pancreatic Diseases; Pancreatic Neoplasms; Pancreatic Polypeptide; Somatostatin	1986
Neoplasia and hyperplasia of pancreatic endocrine tissue in the rat: an immunocytochemical study. Veterinary pathology, 1986, Volume: 23, Issue:1 Topics: Adenoma, Islet Cell; Animals; Female; Glucagon; Hyperplasia; Immunoassay; Insulin; Insulinoma; Islets of Langerhans; Male; Pancreatic Neoplasms; Rats; Rats, Inbred Strains; Species Specificity	1986
Histologic variation in the skin lesions of the glucagonoma syndrome. The American journal of surgical pathology, 1986, Volume: 10, Issue:7 Topics: Adenoma, Islet Cell; Female; Glucagon; Glucagonoma; Humans; Hyperplasia; Male; Middle Aged; Necrosis; Pancreas; Pancreatic Neoplasms; Skin; Skin Diseases; Syndrome	1986
Anti-glucagon insulitis and A-cell hyperplasia of pancreatic islets. Zeitschrift fur mikroskopisch-anatomische Forschung, 1988, Volume: 102, Issue:5 Topics: Animals; Glucagon; Hyperplasia; Immunization, Passive; Inflammation; Insulin; Insulin Secretion; Islets of Langerhans; Mice	1988
Proliferative response of putative preneoplastic hepatocytes to triiodothyronine, aminoacids, glucagon and heparine. Cell biology international reports, 1988, Volume: 12, Issue:3 Topics: Amino Acids; Animals; Cell Division; Diethylnitrosamine; Glucagon; Heparin; Hyperplasia; Liver Neoplasms; Male; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred Strains; Triiodothyronine	1988
Glucagon and prostaglandin E1 stimulation of cyclic adenosine 3', 5'-monophosphate levels and adenylate cyclase activity in benign hyperplastic nodules and malignant hepatomas of ethionine-treated rats. Cancer research, 1973, Volume: 33, Issue:8 Topics: Adenylyl Cyclases; Animals; Carcinoma, Hepatocellular; Cyclic AMP; Ethionine; Glucagon; Hyperplasia; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Phosphoric Diester Hydrolases; Prostaglandins; Rats; Stimulation, Chemical	1973
A2 cell pancreatic microadenomas in a case of multiple endocrine adenomatosis. Cancer, 1971, Volume: 28, Issue:3 Topics: Adrenal Gland Diseases; Adult; Duodenal Ulcer; Female; Glucagon; Histocytochemistry; Humans; Hyperparathyroidism; Hyperplasia; Hypoglycemia; Microscopy, Electron; Multiple Endocrine Neoplasia; Parathyroid Neoplasms; Peptic Ulcer Perforation; Zollinger-Ellison Syndrome	1971
The insulinogenic effect of glucagon in the newborn. Biology of the neonate, 1972, Volume: 20, Issue:1 Topics: Blood Glucose; Female; Glucagon; Humans; Hyperplasia; Infant, Newborn; Insulin; Insulin Secretion; Islets of Langerhans; Pregnancy; Stimulation, Chemical	1972
Persistent neonatal hypoglycaemia: a case report. The New Zealand medical journal, 1969, Volume: 69, Issue:443 Topics: Female; Glucagon; Glucose; Humans; Hyperplasia; Hypoglycemia; Infant, Newborn; Infant, Newborn, Diseases; Islets of Langerhans; Pancreatectomy; Prognosis	1969
The pancreatic islet of infants with severe hypoglycemia. Archives of pathology, 1970, Volume: 89, Issue:3 Topics: Blood Glucose; Epinephrine; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glucose Tolerance Test; Growth Hormone; Humans; Hyperplasia; Hypertrophy; Hypoglycemia; Infant; Infant, Newborn; Insulin; Islets of Langerhans; Leucine; Microscopy, Electron; Radioimmunoassay; Time Factors; Tolbutamide	1970
Glucagon as the portal factor modifying hepatic regeneration. Surgery, 1972, Volume: 72, Issue:1 Topics: Animals; Aspartate Aminotransferases; Autoradiography; DNA; Dogs; Female; Glucagon; Hepatectomy; Hyperplasia; Hypertrophy; Jugular Veins; Liver Circulation; Liver Glycogen; Liver Regeneration; Male; Organ Size; Pancreatectomy; Portacaval Shunt, Surgical; RNA; Thymidine	1972
Alpha cell hyperplasia in calcific pancreatitis associated with hyperparathyroidism. JAMA, 1967, May-29, Volume: 200, Issue:9 Topics: Adenoma; Aged; Calcium; Chronic Disease; Glucagon; Humans; Hyperparathyroidism; Hyperplasia; Islets of Langerhans; Male; Pancreatitis; Parathyroid Neoplasms	1967
Effect of aldosterone, glucagon and growth hormone on the catechol amine content and the evolution of chromaffin hyperplasia in guinea pigs. Experientia, 1966, Apr-15, Volume: 22, Issue:4 Topics: Adrenal Medulla; Aldosterone; Animals; Chromaffin System; Epinephrine; Estradiol; Glucagon; Growth Hormone; Guinea Pigs; Hyperplasia; Norepinephrine	1966
[A case of multiple endocrine neoplasia, type 1, with parathyroid adenoma, multinodular adrenal cortical hyperplasia, islet cell tumor and hyperplasia of thyroid with concomitant hypersecretion of gastrin and total glucagon-like immunoreactivity]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1989, Volume: 78, Issue:3 Topics: Adenoma; Adenoma, Islet Cell; Adrenal Cortex; Female; Gastrins; Glucagon-Like Peptides; Humans; Hydrocortisone; Hyperplasia; Middle Aged; Multiple Endocrine Neoplasia; Pancreatic Neoplasms; Parathyroid Neoplasms; Peptides; Thyroid Gland; Thyroid Hormones	1989