glucagon has been researched along with Glucose Intolerance in 159 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 23 (14.47) | 18.2507 |
| 2000's | 54 (33.96) | 29.6817 |
| 2010's | 63 (39.62) | 24.3611 |
| 2020's | 19 (11.95) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, L; Han, C; Liu, Y; Mehta, S; Peng, X; Yang, G; Zhang, J; Zhang, Y; Zhu, W | 1 |
| Holst, JJ; Laferrère, B; Mark, V; Prasad, M; Shah, A | 1 |
| Anderlova, K; Bendlova, B; Krejci, H; Pacini, G; Sladek, M; Sumova, A; Tura, A; Vankova, M; Vcelak, J; Vejrazkova, D | 1 |
| Hayashi, Y; Ida, T; Kashiwagi, A; Kitada, M; Kitamura, T; Kobayashi, M; Maruyama, N; Miyazato, M; Togawa, T; Yamamoto, Y; Yoshida, M | 1 |
| Bernal-Mizrachi, E; Bozadjieva-Kramer, N; Gittes, GK; Leibowitz, G; Louzada, RA; Lubaczeuski, C | 1 |
| De Leon, DD; Hadjiliadis, D; Kelly, A; Kilberg, MJ; Kubrak, C; Rickels, MR; Rubenstein, RC; Sheikh, S; Stefanovski, D | 1 |
| Chen, Y; Hu, C; Hu, M; Hu, Y; Li, D; Li, X; Liao, S; Liu, B; Liu, J; Lu, Y; Lv, X; Qian, Q; Tan, M; Wang, Y; Wu, D; Xiong, X; Zhang, D; Zhang, Z | 1 |
| Annicotte, JS; Barrachina, C; Cavelier, P; Chavey, C; de Toledo, M; Gromada, X; Lopez-Mejia, IC; Pratlong, M; Tazi, J | 1 |
| Kitamura, T; Kobayashi, M; Kusunoki, Y; Matsuo, T; Namba, M; Satoh, H; Tokushima, M; Watada, H | 1 |
| Baldi, S; Frascerra, S; Mengozzi, A; Natali, A; Nesti, L; Tricò, D | 1 |
| Armaghanian, N; Brand-Miller, J; Chua, EL; Hetherington, J; Markovic, TP; Parameswaran, V; Steinbeck, K | 1 |
| Kadowaki, S; Kaga, H; Kawamori, R; Nakagata, T; Sato, M; Satoh, H; Someya, Y; Sugimoto, D; Tamura, Y; Watada, H; Yamasaki, N | 1 |
| Bennett, J; Hill, DJ; Strutt, BJ; Szlapinski, SK | 1 |
| Barker, G; Bernal-Mizrachi, E; Blandino-Rosano, M; Bozadjieva Kramer, N; Caicedo, A; Gittes, GK; Lubaczeuski, C | 1 |
| Chen, X; DeFronzo, RA; Maldonado, E; Tripathy, D | 1 |
| Bahl, V; Glaser, B; Kaestner, KH; Lee May, C; Perez, A | 1 |
| Abiru, N; Akazawa, S; Haraguchi, A; Hasegawa, Y; Horie, I; Ito, A; Kawakami, A; Miura, K; Miura, S; Miwa, M; Nagata, A; Natsuda, S; Shigeno, R | 1 |
| Brown, GS; Diaz, M; Lackey, AI; Sato, PY; Snyder, J; Yuzhen, T | 1 |
| De Leon, DD; Eiel, JN; Gallop, R; Hadjiliadis, D; Kelly, A; Localio, R; Nyirjesy, SC; Peleckis, AJ; Rickels, MR; Rubenstein, RC; Sheikh, S; Sidhaye, A; Stefanovski, D | 1 |
| Böni-Schnetzler, M; Dalmas, E; Donath, MY; Dror, E; Goetz, N; Herrera, PL; Koch, N; Makshana, V; Meier, DT; Nordmann, TM; Schulze, F; Stawiski, M; Thorel, F; Traub, S | 1 |
| Junker, AE | 1 |
| Chan, HC; Chung, YW; Guo, JH; Huang, WQ; Ruan, YC; Yu, MK; Zhang, XH | 1 |
| Haluzík, M; Holubová, M; Hrubá, L; Kuneš, J; Maletínská, L; Mikulášková, B; Pražienková, V; Železná, B; Zemenová, J | 1 |
| Kelly, VP; Naito, A; Nakajima, M; Nakajima, O; Nakano, H; Nohara, H; Okano, S; Saitoh, S; Shirasawa, N; Takahashi, K; Tanaka, T; Yamamoto, M | 1 |
| Basco, D; Berney, X; Dolci, W; Herrera, P; Rorsman, P; Salehi, A; Spiliotis, I; Tarasov, A; Tarussio, D; Thorens, B; Zhang, Q | 1 |
| Dunai, J; Kilpatrick, CR; Oestricker, LZ; Patterson, BW; Reeds, DN; Sterl, K; Wallendorf, MJ; Wang, S; Wice, BM | 1 |
| Heinla, I; Jagomäe, T; Koppel, T; Pallase, M; Plaas, M; Seppa, K; Terasmaa, A; Toots, M; Vasar, E | 1 |
| Araujo, TR; Bonfleur, ML; Boschero, AC; Carneiro, EM; da Silva, JA; Freitas, IN; Lubaczeuski, C; Magalhães, EA; Ribeiro, ES; Ribeiro, RA; Silva, JN; Vettorazzi, JF | 1 |
| Broberg, B; Christensen, KB; Feldt-Rasmussen, B; Fuglsang, S; Holst, JJ; Hornum, M; Idorn, T; Madsen, JL; Rydahl, C | 1 |
| Fujimoto, K; Ichikawa, R; Kitamura, T; Kobayashi, M; Motomiya, T; Shichiri, M; Takano, K | 1 |
| Abiru, N; Akazawa, S; Ando, T; Haraguchi, A; Hasegawa, Y; Higashijima, A; Horie, I; Ito, A; Kawakami, A; Masuzaki, H; Miura, K; Mori, Y; Natsuda, S; Nozaki, A; Yoshida, A | 1 |
| Ahlström, H; Bergquist, J; Bergsten, P; Cadamuro, J; Forslund, A; Göpel, S; Kristinsson, H; Kullberg, J; Manell, H; Mörwald, K; Sargsyan, E; Staaf, J; Ubhayasekera, SJK; Weghuber, D; Zsoldos, F | 1 |
| Chen, C; Guo, J; Li, B; Ou, K; Wang, C; Xu, J; Zuo, Z | 1 |
| Akiyama, M; Hambro, B; Hu, J; Kennedy, RT; Kulkarni, RN; Liew, CW; Lu, S; Martinez, R | 1 |
| Bano, G | 1 |
| Bazotte, RB; Curi, R; de Castro R Marques, A; Minguetti-Câmara, VC; Obici, S; Tavoni, TM | 1 |
| Flatt, PR; Hamid, MH; Irwin, N; McCluskey, JT; Moffett, RC; Vasu, S | 1 |
| Itoh, N; Konishi, M; Mochiyama, T; Murata, Y; Nishio, K; Ohta, H; Shimada, M | 1 |
| Abdul-Ghani, M; Arya, R; DeFronzo, RA; Fourcaudot, M; Hansis-Diarte, A; Jenkinson, CP; Kanat, M; Norton, L; Tripathy, D; Winner, D | 1 |
| Gu, JJ; Hou, LQ; Liu, YH; Zhao, TY | 1 |
| Chan, O; D'Agostino, G; Diano, S; DiLeone, RJ; Elsworth, JD; Harvey, BK; Jeong, JK; Kibbey, RG; Kim, JD; Myöhänen, T; Richie, CT; Savolainen, M; Toda, C; Zeiss, CJ | 1 |
| Aulinger, BA; D'Alessio, DA; Drazen, DL; Seeley, RJ; Smith, EP; Ulrich-Lai, Y; Vahl, TP; Woods, SC | 1 |
| Brandt, C; Galle, P; Gehl, J; Hansen, JB; Hansen, RH; Hojman, P; Mandrup-Poulsen, T; Olsen, CH; Pedersen, BK | 1 |
| Gyldenløve, M; Holst, JJ; Knop, FK; Skov, L; Storgaard, H; Vilsbøll, T | 1 |
| Eguchi, H; Fujita, Y; Imagawa, A; Iwahashi, H; Kozawa, J; Nagano, H; Okita, K; Shimomura, I; Uno, S; Yoneda, S; Yoshikawa, A | 1 |
| Cannone, M; D'Ascia, SL; Guise, TA; Lacampagne, A; Marks, AR; Marziliano, N; Pagano, G; Reiken, S; Santulli, G; Sardu, C; Trimarco, B; Xie, W | 1 |
| Chen, H; Chen, Y; Liu, M; Luo, J; Wang, T; Wang, X; Yang, Y; You, P; Zhao, Y; Zheng, C; Zhou, W | 1 |
| Albury-Warren, TM; Altomare, DA; Masternak, MM; Pandey, V; Spinel, LP | 1 |
| Holst, B; Holst, JJ; Jensen, SM; Madsen, AN; Pedersen, J; Poulsen, SS; Quistorff, B; Steenberg, VR; Windeløv, JA | 1 |
| Ahlkvist, L; Ahrén, B; Fosgerau, K; Omar, B; Valeur, A | 1 |
| Gluud, L; Holst, JJ; Junker, AE; Knop, FK; Vilsbøll, T | 1 |
| Chae, KS; Choi, OK; Chung, SS; Ham, DS; Jung, HS; Kim, JW; Kim, MJ; Lee, H; Park, KS; Yoon, KH | 1 |
| Bergsten, P; Cen, J; Ciba, I; Forslund, A; Kristinsson, H; Manell, H; Manukyan, L; Staaf, J; Stenlid, R | 1 |
| Astiarraga, B; Baldi, S; Bizzotto, R; Ferrannini, E; Frascerra, S; Heise, T; Mari, A; Muscelli, E; Pieber, TR | 1 |
| Engelhardt, JF; Gibson-Corley, K; Hara, M; He, N; Liang, B; Norris, AW; Ode, KL; Philipson, LH; Sun, X; Tyler, SR; Uc, A; Wang, K; Xie, W; Yi, Y | 1 |
| Brozinick, JT; Chen, S; Geldenhuys, WJ; Kusminski, CM; Li, WH; Sanders, PE; Scherer, PE; Spurgin, SB; Sun, K; Unger, RH; Wang, QA; Ye, R | 1 |
| Chowdhury, S; Dunai, J; Kilpatrick, R; Oestricker, LZ; Patterson, BW; Reeds, DN; Wallendorf, MJ; Wang, S; Wice, BM | 1 |
| Jiang, G; Liang, G; Song, X; Wang, F; Xu, H; Zhang, L; Zhou, L | 1 |
| Ding, L; Han, L; Li, Y; Yin, Y; Zhang, W; Zhao, J | 1 |
| Bree, AJ; Daphna-Iken, D; Fisher, SJ; Kahn, BB; Puente, EC; Reno, CM; Routh, VH; Sheng, Z | 1 |
| Ahlqvist, E; Fritsche, A; Gallwitz, B; Groop, L; Hakaste, LH; Häring, HU; Heni, M; Machann, J; Schick, F; Stefan, N; Tuomi, T; Van Obberghen, E; Wagner, R | 1 |
| Abdul-Ghani, M; Adams, J; Al Jobori, H; Cersosimo, E; Daniele, G; DeFronzo, RA; Triplitt, C | 1 |
| Baskin, DG; Cummings, BP; Digitale, EK; Graham, JL; Griffen, SC; Havel, PJ; Reed, BJ; Stanhope, KL; Sweet, IR | 1 |
| Ahrén, B | 1 |
| Bokhari, S; Emerson, P; Gupta, A; Israelian, Z; Meyer, C | 1 |
| Bengtsson, M; Eliasson, L; Galvanovskis, J; Håkansson, J; Lundquist, I; Olofsson, CS; Partridge, C; Rorsman, P; Salehi, A; Semb, H; SörhedeWinzell, M; Xian, X | 1 |
| Ford, EL; Herrera, PL; Hu, J; Kawamori, D; Kulkarni, RN; Kurpad, AJ; Liew, CW; McGuinness, OP; Polonsky, KS; Shih, JL | 1 |
| Bellmann, K; Blanchard, PG; Brûlé, S; Deshaies, Y; Festuccia, WT; Houde, VP; Marette, A | 1 |
| Grønbaek, H; Holland-Fischer, P; Mengel, A; Nielsen, MF; Schmitz, O; Tønner-Nielsen, D; Vilstrup, H | 1 |
| Baggio, LL; Bahrami, J; Drucker, DJ; Li, K; Longuet, C | 1 |
| Holst, JJ; Knop, FK; Krarup, T; Larsen, S; Madsbad, S; Vilsbøll, T | 1 |
| Cherrington, AD; Coate, KC; Farmer, B; Moore, MC; Neal, DW; Roop, J; Scott, M; Smith, M; Williams, P | 1 |
| Arbeláez, AM; Cryer, PE; Ramanathan, RP | 1 |
| Beaudeux, JL; Cottart, CH; Cynober, L; Fabre, EE; Golmard, JL; Hebert-Schuster, M; Laguillier-Morizot, C; Nivet-Antoine, V; Raynaud-Simon, A | 1 |
| Allister, EM; Bhattacharjee, A; Koshkin, V; Prentice, KJ; Robson-Doucette, CA; Sereda, SB; Shirihai, OS; Sultan, S; Wheeler, MB; Wikstrom, JD | 1 |
| DeFronzo, RA; Doiron, B; Hu, W; Norton, L | 1 |
| Bagger, JI; Hansen, KB; Holst, JJ; Knop, FK; Vilsbøll, T | 1 |
| Crimmins, DL; Dunai, J; Ladenson, JH; Patterson, BW; Polonsky, KS; Reeds, DN; Tran, HD; Villareal, DT; Wallendorf, MJ; Wice, BM | 1 |
| Allister, EM; Bhattacharjee, A; Wheeler, MB | 1 |
| Chen, Z; Cho, KW; Jiang, L; Ren, D; Rui, L; Sasaki, Y; Shen, H; Sheng, L; Zhou, Y | 1 |
| Cree-Green, M; Mizokami-Stout, K; Nadeau, KJ | 1 |
| Inaba, W; Kamata, K; Mizukami, H; Takahashi, K; Tsuboi, K; Yagihashi, S | 1 |
| Engelhardt, JF; Evans, TI; Fisher, JT; Hu, S; Keiser, NW; Lei, D; Li, G; Liang, B; Meyerholz, DK; Norris, AW; Olivier, AK; Stewart, ZA; Sui, H; Sun, X; Wang, K; Xie, W; Yan, Z; Yi, Y; Zhou, W | 1 |
| Feng, ZP; Gaisano, HY; Gilon, P; Herrera, PL; Huang, YC; Karimian, N; Rupnik, MS | 1 |
| Aoki, K; Kamiyama, H; Masuda, K; Terauchi, Y; Togashi, Y | 1 |
| Chen, C; Chen, Z; Han, Y; Shen, J; Zhu, X | 1 |
| Barosa, C; Basu, A; Basu, R; Carter, R; Dube, S; Jones, J; Rizza, RA | 1 |
| Gustafson, LA; Kuipers, F; Meijer, AJ; Romijn, JA; Sauerwein, HP; Wiegman, C | 1 |
| Carr, RD; Deacon, CF; Knudsen, LB; Larsen, MO; Ribel, U; Rolin, B; Sturis, J; Westergaard, L; Wilken, M | 1 |
| Chang, AM; Halter, JB | 1 |
| Hanafusa, T; Imagawa, A; Iwahashi, H; Li, M; Matsuzawa, Y; Miyagawa, J; Moriwaki, M; Tochino, Y; Yamagata, K; Yamamoto, K | 1 |
| Andrikopoulos, S; Cnop, M; Hull, RL; Kahn, SE; Prigeon, RL; Verchere, CB; Vidal, J; Wang, F | 1 |
| Adamson, U; Ahrén, B; Guldstrand, M | 1 |
| Mkrtumian, AM | 1 |
| Andreassen, OA; Beal, MF; Browne, SE; Dedeoglu, A; Ferrante, RJ; Habener, JF; Hughes, DB; Leech, CA; Stanojevic, V; Thomas, MK | 1 |
| Dostou, JM; Gerich, JE; Mariuz, PR; Meyer, C; Popa, EM; Reichman, RC; Welle, SL; Woerle, HJ | 1 |
| Fritsche, A; Häring, H; Machicao, F; Shirkavand, F; Stumvoll, M; Tschritter, O | 1 |
| Edenborough, FP; Mackie, AD; Thornton, SJ | 1 |
| Canettieri, G; Jhala, US; Krajewski, S; Kulkarni, RN; Lin, X; Montminy, M; Reed, J; Screaton, RA; Walker, J; White, M | 1 |
| Li, JS; Li, N; Li, WQ; Yu, WK | 1 |
| Ahrén, B; Holst Jj, Jj; Olsson, T; Pacini, G; Rask, E; Söderberg, S; Tura, A | 1 |
| Ferrannini, E; Gastaldelli, A; Mari, A; Natali, A; Ostergard, T; Schmitz, O | 1 |
| Guo, Y; Houle, D; Kopchick, JJ; Liu, JL; Liu, YL; Lu, Y; Robertson, K; Tang, Z | 1 |
| Sato, F; Tamura, Y | 1 |
| Andersen, O; Andersen, UB; Deacon, CF; Haugaard, SB; Holst, JJ; Iversen, J; Madsbad, S; Nielsen, JO | 1 |
| Ciemerych, MA; Kushner, JA; Long, SY; Sicinska, E; Sicinski, P; Teta, M; Wartschow, LM; White, MF | 1 |
| Brunicardi, FC; DeMayo, FJ; Liu, SH; Magnusson, J; Norman, M; Wang, XP; Yang, J | 1 |
| Hanefeld, M; Henkel, E; Koehler, C; Leonhardt, W; Menschikowski, M | 1 |
| Anini, Y; Chrétien, M; Fleck, E; Gyamera-Acheampong, C; Kauri, LM; Mbikay, M; Schmidt, G; Scott, FW; Sirois, F | 1 |
| Cassidy, RS; Flatt, PR; Gault, VA; Green, BD; Irwin, N | 1 |
| Basu, R; Bock, G; Campioni, M; Chittilapilly, E; Cobelli, C; Dalla Man, C; Rizza, R; Toffolo, G | 1 |
| Arita, Y; Funakoshi, A; Hisano, T; Igarashi, H; Ito, T; Kawabe, K; Sumii, T; Takayanagi, R; Yamanaka, T | 1 |
| Basu, R; Bock, G; Chandramouli, V; Chittilapilly, E; Cobelli, C; Landau, BR; Rizza, RA; Toffolo, G | 1 |
| Gallo, S; Hanefeld, M; Henkel, E; Koehler, C; Siegert, G | 1 |
| Cassidy, RS; Flatt, PR; Gault, VA; Irwin, N; McClean, PL | 1 |
| Cassidy, RS; Flatt, PR; Gault, VA; Holst, JJ; Irwin, N; McClean, PL | 1 |
| Baron, MA; Deacon, CF; Foley, JE; Holst, JJ; Landin-Olsson, M; Rendell, M; Rochotte, E; Rosenstock, J | 1 |
| Fagerholm, V; Rahkonen, O; Savontaus, E; Scheinin, M | 1 |
| Baller, B; Ellrichmann, M; Holst, JJ; Meier, JJ; Nauck, MA; Schmidt, WE; Vollmer, K | 1 |
| Björck, IM; Holst, JJ; Nilsson, AC; Ostman, EM | 1 |
| Ahrén, B; Dunning, BE; Foley, JE; Pratley, RE; Soubt, M | 1 |
| Prasanna, BM; Shah, P; Sidhu, SS; Srikanta, SS; Tandon, RK | 1 |
| Alberti, KG; Berrish, TS; Hetherington, CS; Walker, M | 1 |
| Göke, B; Göke, R; McGregor, GP | 1 |
| Bruno, A; Cassader, M; Cavallo-Perin, P; Gruden, G; Pagano, G; Scaglione, L | 1 |
| Kajikawa, S | 1 |
| Waeber, G | 1 |
| Bech, K; Beck-Nielsen, H; Damsbo, P; Eldrup, E; Hartling, SG; Madsbad, S; Røder, ME; Vølund, A | 1 |
| Engelman, K; Teff, KL | 1 |
| Becker, HD; Benz, S; Büsing, M; Gwodzinski, A; Hopt, UT; Nauck, MA; Pfeffer, F; Zink, R | 1 |
| Ahrén, B; Larsson, H | 4 |
| Auerbach, AB; Brown, TJ; Brubaker, PL; Drucker, DJ; Joyner, AL; MaClusky, N; Scrocchi, LA | 1 |
| Kuikka, JT; Turpeinen, AK; Uusitupa, MI; Vanninen, E | 1 |
| Ito, C | 1 |
| Gerich, JE | 1 |
| Bonner-Weir, S; Clark, J; Kubstrup, C; Levisetti, M; Pick, A; Polonsky, KS; Pugh, W | 1 |
| Akai, H; Chiba, M; Hinokio, Y; Hirai, A; Hirai, M; Kasuga, S; Ohtomo, M; Satoh, Y; Suzuki, S; Toyota, T | 1 |
| Ahlgren, U; Edlund, H; Jonsson, J; Jonsson, L; Simu, K | 1 |
| Arnold, R; Byrne, MM; Gliem, K; Göke, B; Katschinski, M; Polonsky, KS; Wank, U | 1 |
| Barreca, T; Bruno, E; Cataldi, A; Corsini, G; Franceschini, R; Robaudo, C; Rolandi, E; Russo, R | 1 |
| Marks, V; Morgan, L; Ranganath, L; Sedgwick, I; Wright, J | 1 |
| Basu, A; Basu, R; Rizza, R; Shah, P | 1 |
| Ikegami, H; Miki, T; Ogihara, T; Yamada, K; Yoneda, H | 1 |
| Ban, N; Fujimoto, S; Hashimoto, H; Ihara, Y; Jomori, T; Kajikawa, M; Kubota, A; Kuroe, A; Miyawaki, K; Miyazaki, J; Niwa, H; Seino, Y; Tashiro, F; Tsuda, K; Yamada, Y; Yamashita, T; Yano, H | 1 |
| Ahrén, B; Bertrand, G; Bockaert, J; Brabet, P; Jamen, F; Persson, K; Puech, R; Rodriguez-Henche, N | 1 |
| Ipp, E | 1 |
| Fritsche, A; Hardt, E; Häring, H; Stefan, N; Stumvoll, M | 2 |
| Ahrén, B; Gingerich, RL; Nayak, S; Persson, K; Wada, E; Wada, K | 1 |
| Doyle, ME; Egan, JM; Perfetti, R; Zhou, J | 1 |
| Brubaker, PL; Kalitsky, J; LaGreca, J; Rocca, AS | 1 |
| Holst, JJ; Juhl, C; März, W; Nauck, MA; Nauck, MS; Pørksen, N; Ritzel, R; Schmiegel, WH; Schmitz, O; Schulte, M | 1 |
| Damholt, MB; Hilsted, LM; Holst, JJ; Hughes, TE; Madsbad, S; Michelsen, BK; Toft-Nielsen, MB | 1 |
| Gjinovci, A; Hagenfeldt-Johansson, KA; Herrera, PL; Ishihara, H; Wang, H; Wollheim, CB | 1 |
| Ahrén, B; Holst, JJ; Reimer, MK | 1 |
| Banerji, MA | 1 |
11 review(s) available for glucagon and Glucose Intolerance
| Article | Year |
|---|---|
The role of incretin hormones and glucagon in patients with liver disease.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose Intolerance; Humans; Incretins; Insulin; Liver; Mice; Non-alcoholic Fatty Liver Disease | 2017 |
Insulin resistance in type 2 diabetic youth.
Topics: Adolescent; Body Mass Index; C-Peptide; Child; Diabetes Mellitus, Type 2; Exercise Tolerance; Female; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Metformin; Obesity; Phenotype; Young Adult | 2012 |
Aging and insulin secretion.
Topics: Adult; Aged; Aged, 80 and over; Aging; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Intolerance; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Middle Aged; Nutrition Surveys; Peptide Fragments | 2003 |
Cystic fibrosis-related diabetes.
Topics: Administration, Oral; Breast Feeding; Cystic Fibrosis; Diabetes Mellitus; Diabetic Angiopathies; Dietary Supplements; Female; Glucagon; Glucose; Glucose Intolerance; Humans; Insulin; Islets of Langerhans; Lipid Metabolism; Lung Transplantation; Nutritional Physiological Phenomena; Pregnancy; Pregnancy in Diabetics; Prognosis; Proteins | 2003 |
[Impaired hepatic glucose metabolism].
Topics: Glucagon; Glucose; Glucose Intolerance; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Insulin Resistance; Lipid Metabolism; Liver; Obesity; Postprandial Period | 2005 |
Clinical measures of islet function: usefulness to characterize defects in diabetes.
Topics: Arginine; Blood Glucose; Diabetes Mellitus; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Reference Values | 2008 |
[Dysfunction of the pancreatic beta cells observed in non-insulin-dependent diabetes].
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Insulin; Insulin Secretion; Islets of Langerhans; Monosaccharide Transport Proteins; Peptide Fragments; Protein Precursors | 1993 |
[Leanness and diabetes mellitus].
Topics: Biomarkers; Blood Pressure; Body Mass Index; Diabetes Mellitus, Type 2; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Nutritional Status; Protein Precursors; Thinness | 1997 |
Metabolic abnormalities in impaired glucose tolerance.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus; Glucagon; Glucose; Glucose Intolerance; Humans; Hyperglycemia; Insulin; Insulin Resistance; Middle Aged; Prevalence; Risk Factors; United States | 1997 |
Impaired glucose tolerance: the irrepressible alpha-cell?
Topics: Female; Glucagon; Glucose Intolerance; Humans; Insulin Resistance; Islets of Langerhans | 2000 |
Impaired beta-cell and alpha-cell function in African-American children with type 2 diabetes mellitus--"Flatbush diabetes".
Topics: Adolescent; Adult; Black People; Body Mass Index; C-Peptide; Child; Diabetes Mellitus, Type 2; Food; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Puberty | 2002 |
17 trial(s) available for glucagon and Glucose Intolerance
| Article | Year |
|---|---|
Ingestion of an exogenous ketone monoester improves the glycemic response during oral glucose tolerance test in individuals with impaired glucose tolerance: A cross-over randomized trial.
Topics: 3-Hydroxybutyric Acid; Area Under Curve; Blood Glucose; C-Peptide; Cross-Over Studies; Eating; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glucose Intolerance; Glucose Tolerance Test; Glycemic Control; Humans; Insulin; Ketones; Male; Middle Aged | 2021 |
Effect of Sitagliptin on Islet Function in Pancreatic Insufficient Cystic Fibrosis With Abnormal Glucose Tolerance.
Topics: Adolescent; Adult; Cystic Fibrosis; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Exocrine Pancreatic Insufficiency; Female; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin Secretion; Islets of Langerhans; Male; Sitagliptin Phosphate; Young Adult | 2021 |
Basal glucagon hypersecretion and response to oral glucose load in prediabetes and mild type 2 diabetes.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin Resistance; Male; Middle Aged; Prediabetic State; Severity of Illness Index; Young Adult | 2019 |
Impaired early-phase suppression of glucagon secretion after glucose load is associated with insulin requirement during pregnancy in gestational diabetes.
Topics: Adult; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Follow-Up Studies; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Pregnancy; Prognosis; Prospective Studies | 2020 |
Strong association between insulin-mediated glucose uptake and the 2-hour, not the fasting plasma glucose concentration, in the normal glucose tolerance range.
Topics: Adult; Blood Glucose; Fasting; Female; Glucagon; Glucose Clamp Technique; Glucose Intolerance; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin; Linear Models; Male; Mexican Americans; Middle Aged; Muscle, Skeletal; Prediabetic State; Reference Values | 2014 |
Diabetic and nondiabetic patients with nonalcoholic fatty liver disease have an impaired incretin effect and fasting hyperglucagonaemia.
Topics: Adult; Blood Glucose; C-Reactive Protein; Diabetes Mellitus, Type 2; Fasting; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Humans; Incretins; Insulin; Male; Middle Aged; Non-alcoholic Fatty Liver Disease | 2016 |
Shift to Fatty Substrate Utilization in Response to Sodium-Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes.
Topics: 3-Hydroxybutyric Acid; Algorithms; Benzhydryl Compounds; C-Reactive Protein; Carbohydrate Metabolism; Diabetes Mellitus, Type 2; Energy Metabolism; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Glucosides; Glycosuria; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Lipid Metabolism; Lipolysis; Membrane Transport Modulators; Renal Elimination; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Time Factors | 2016 |
Hormonal Responses to Cholinergic Input Are Different in Humans with and without Type 2 Diabetes Mellitus.
Topics: Administration, Oral; Adult; Bethanechol; Blood Glucose; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Hormones; Humans; Insulin; Islets of Langerhans; Male; Middle Aged; Muscarinic Agonists; Neurotensin; Non-Randomized Controlled Trials as Topic; Pancreatic Polypeptide; Postprandial Period | 2016 |
Glucagon suppression during OGTT worsens while suppression during IVGTT sustains alongside development of glucose intolerance in patients with chronic pancreatitis.
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Male; Middle Aged; Pancreatitis, Chronic | 2010 |
Partial inhibition of insulin secretion results in glucose intolerance but not hyperglucagonemia.
Topics: Adult; Blood Glucose; C-Peptide; Diazoxide; Female; Glucagon; Glucose Intolerance; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; KATP Channels; Male; Sulfonylurea Compounds; Young Adult | 2011 |
Impaired incretin-induced amplification of insulin secretion after glucose homeostatic dysregulation in healthy subjects.
Topics: Adult; Blood Glucose; C-Peptide; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Clamp Technique; Glucose Intolerance; Glucose Tolerance Test; Humans; Incretins; Infusions, Intravenous; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Kinetics; Male; Severity of Illness Index; Young Adult | 2012 |
Xenin-25 amplifies GIP-mediated insulin secretion in humans with normal and impaired glucose tolerance but not type 2 diabetes.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucose; Glucose Intolerance; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Neurotensin | 2012 |
Mosapride citrate, a 5-HT₄ receptor agonist, increased the plasma active and total glucagon-like peptide-1 levels in non-diabetic men.
Topics: Adult; Benzamides; Blood Glucose; Gastric Inhibitory Polypeptide; Gastrointestinal Agents; Gastrointestinal Tract; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Humans; Hypoglycemia; Hypoglycemic Agents; Incretins; Insulin; Male; Morpholines; Postprandial Period; Serotonin 5-HT4 Receptor Agonists; Up-Regulation | 2013 |
Effects of the dipeptidyl peptidase-IV inhibitor vildagliptin on incretin hormones, islet function, and postprandial glycemia in subjects with impaired glucose tolerance.
Topics: Adamantane; Blood Glucose; C-Peptide; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Humans; Inulin; Kinetics; Male; Nitriles; Placebos; Postprandial Period; Pyrrolidines; Vildagliptin | 2008 |
Including indigestible carbohydrates in the evening meal of healthy subjects improves glucose tolerance, lowers inflammatory markers, and increases satiety after a subsequent standardized breakfast.
Topics: Adiponectin; Adult; Biomarkers; Blood Glucose; Carbohydrates; Digestion; Fatty Acids, Nonesterified; Female; Food Analysis; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Inflammation; Insulin; Interleukin-6; Interleukin-8; Male; Satiety Response; Triglycerides | 2008 |
The effects of coenzyme Q10 treatment on maternally inherited diabetes mellitus and deafness, and mitochondrial DNA 3243 (A to G) mutation.
Topics: Adult; C-Peptide; Coenzymes; Deafness; Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; DNA, Mitochondrial; Family Health; Female; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Hearing; Humans; Lactic Acid; Male; Middle Aged; Mothers; Point Mutation; Time Factors; Treatment Outcome; Ubiquinone | 1998 |
Glucagon-like peptide 1 increases secretory burst mass of pulsatile insulin secretion in patients with type 2 diabetes and impaired glucose tolerance.
Topics: Aged; Aged, 80 and over; Blood Glucose; Diabetes Mellitus, Type 2; Entropy; Female; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Hormones; Humans; Injections, Intravenous; Insulin; Insulin Secretion; Male; Middle Aged; Osmolar Concentration; Peptide Fragments; Protein Precursors; Pulsatile Flow; Reference Values | 2001 |
131 other study(ies) available for glucagon and Glucose Intolerance
| Article | Year |
|---|---|
Glucagon Potentiates Insulin Secretion Via β-Cell GCGR at Physiological Concentrations of Glucose.
Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose; Glucose Intolerance; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Glucagon; Signal Transduction | 2021 |
Glucagon-like peptide-1 effect on β-cell function varies according to diabetes remission status after Roux-en-Y gastric bypass.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Gastric Bypass; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose; Glucose Intolerance; Humans; Insulin; Retrospective Studies | 2022 |
The rs10830963 Polymorphism of the MTNR1B Gene: Association With Abnormal Glucose, Insulin and C-peptide Kinetics.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose; Glucose Intolerance; Humans; Insulin; Insulin Resistance; Kinetics; Male; Prediabetic State; Receptor, Melatonin, MT2 | 2022 |
A newly developed glucagon sandwich ELISA is useful for more accurate glucagon evaluation than the currently used sandwich ELISA in subjects with elevated plasma proglucagon-derived peptide levels.
Topics: Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Glicentin; Glucagon; Glucose; Glucose Intolerance; Humans; Peptide Hormones; Proglucagon | 2023 |
Time-dependent effects of endogenous hyperglucagonemia on glucose homeostasis and hepatic glucagon action.
Topics: Animals; Glucagon; Glucose; Glucose Intolerance; Homeostasis; Hypoglycemia; Liver; Mice | 2023 |
Dysregulated insulin in pancreatic insufficient cystic fibrosis with post-prandial hypoglycemia.
Topics: Adolescent; Area Under Curve; Blood Glucose; C-Peptide; Cystic Fibrosis; Exocrine Pancreatic Insufficiency; Female; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Hypoglycemia; Incretins; Insulin; Insulin Secretion; Male; Young Adult | 2020 |
Sustained ER stress promotes hyperglycemia by increasing glucagon action through the deubiquitinating enzyme USP14.
Topics: Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Gene Knockdown Techniques; Glucagon; Gluconeogenesis; Glucose; Glucose Intolerance; Hyperglycemia; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Ubiquitin Thiolesterase | 2019 |
Lamin C Counteracts Glucose Intolerance in Aging, Obesity, and Diabetes Through β-Cell Adaptation.
Topics: Aging; Animals; Blood Glucose; Diabetes Mellitus; Energy Metabolism; Glucagon; Glucose Intolerance; Insulin; Insulin-Secreting Cells; Lamin Type A; Mice; Mice, Transgenic; Obesity; Pancreas | 2020 |
Plasma glucagon levels measured by sandwich ELISA are correlated with impaired glucose tolerance in type 2 diabetes.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Female; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Male; Middle Aged | 2020 |
A Protein/Lipid Preload Attenuates Glucose-Induced Endothelial Dysfunction in Individuals with Abnormal Glucose Tolerance.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Fats; Dietary Proteins; Endothelium, Vascular; Fasting; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Postprandial Period; Young Adult | 2020 |
Hypoglycemia in cystic fibrosis during an extended oral glucose tolerance test.
Topics: Adolescent; Adult; Blood Glucose; Cystic Fibrosis; Fasting; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Male; Young Adult | 2020 |
Increased alpha and beta cell mass during mouse pregnancy is not dependent on transdifferentiation.
Topics: Animals; Cell Proliferation; Cell Transdifferentiation; Female; Glucagon; Glucagon-Secreting Cells; Glucose Intolerance; Insulin; Insulin-Secreting Cells; Male; Mice, Inbred C57BL; Pregnancy | 2021 |
Glucagon Resistance and Decreased Susceptibility to Diabetes in a Model of Chronic Hyperglucagonemia.
Topics: Animals; Blood Glucose; Body Weight; Disease Models, Animal; Disease Susceptibility; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Glucose Intolerance; Insulin; Insulin Secretion; Mechanistic Target of Rapamycin Complex 1; Mice; Receptors, Glucagon; Signal Transduction; Tuberous Sclerosis Complex 2 Protein | 2021 |
Impaired Suppression of Glucagon in Obese Subjects Parallels Decline in Insulin Sensitivity and Beta-Cell Function.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Glucose Clamp Technique; Glucose Intolerance; Glucose Tolerance Test; Hispanic or Latino; Humans; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Middle Aged; Obesity; Prediabetic State; United States; Veterans | 2021 |
Genetic activation of α-cell glucokinase in mice causes enhanced glucose-suppression of glucagon secretion during normal and diabetic states.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Diet, High-Fat; Fasting; Female; Glucagon; Glucagon-Secreting Cells; Glucokinase; Glucose; Glucose Intolerance; Hyperinsulinism; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Mice | 2021 |
Bihormonal dysregulation of insulin and glucagon contributes to glucose intolerance development at one year post-delivery in women with gestational diabetes: a prospective cohort study using an early postpartum 75-g glucose tolerance test.
Topics: Adult; Blood Glucose; Body Mass Index; Diabetes, Gestational; Fasting; Female; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Pregnancy; Prospective Studies | 2021 |
GRK2 contributes to glucose mediated calcium responses and insulin secretion in pancreatic islet cells.
Topics: Animals; Calcium; Cell Line; Cyclic AMP; Diabetes Mellitus, Type 2; Diet, High-Fat; Down-Regulation; G-Protein-Coupled Receptor Kinase 2; Glucagon; Glucose; Glucose Intolerance; Glucose Tolerance Test; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Lipid Peroxidation; Mice; Mice, Knockout; Obesity | 2021 |
Pancreatic α Cell-Derived Glucagon-Related Peptides Are Required for β Cell Adaptation and Glucose Homeostasis.
Topics: Adaptation, Physiological; Aging; Animals; Diet, High-Fat; Diphtheria Toxin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Glucose; Glucose Intolerance; Glucose Tolerance Test; Homeostasis; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mice, Inbred C57BL; Mice, Knockout; Obesity; Proprotein Convertases; Rats; Stress, Physiological | 2017 |
Glucose-Sensitive CFTR Suppresses Glucagon Secretion by Potentiating KATP Channels in Pancreatic Islet α Cells.
Topics: Animals; Calcium; Cell Line; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Gene Expression; Gene Knockdown Techniques; Glucagon; Glucagon-Secreting Cells; Glucose; Glucose Intolerance; KATP Channels; Mice; Mice, Mutant Strains; Mutation | 2017 |
Lipidized prolactin-releasing peptide improved glucose tolerance in metabolic syndrome: Koletsky and spontaneously hypertensive rat study.
Topics: Adipose Tissue; Animals; Blood Glucose; Blood Pressure; Body Weight; Brain; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Hypertension; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Lipids; Male; Metabolic Syndrome; Obesity; Prolactin-Releasing Hormone; Rats, Inbred SHR | 2018 |
5-aminolevulinic acid (ALA) deficiency causes impaired glucose tolerance and insulin resistance coincident with an attenuation of mitochondrial function in aged mice.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Blood Glucose; Glucagon; Gluconeogenesis; Glucose Intolerance; Insulin; Insulin Resistance; Levulinic Acids; Mice; Mice, Transgenic; Mitochondria; Signal Transduction | 2018 |
α-cell glucokinase suppresses glucose-regulated glucagon secretion.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Transport; Female; Gene Expression; Glucagon; Glucagon-Secreting Cells; Glucokinase; Glucose; Glucose Intolerance; Hypoglycemia; Insulin; KATP Channels; Liver; Male; Mice; Mice, Knockout | 2018 |
Cholinergic signaling mediates the effects of xenin-25 on secretion of pancreatic polypeptide but not insulin or glucagon in humans with impaired glucose tolerance.
Topics: Adult; Atropine; Blood Glucose; Cross-Over Studies; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucose Intolerance; Heart Rate; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Neurotensin; Pancreatic Polypeptide; Receptors, Cholinergic; Signal Transduction | 2018 |
Preventive treatment with liraglutide protects against development of glucose intolerance in a rat model of Wolfram syndrome.
Topics: Animals; Blood Glucose; Calmodulin-Binding Proteins; Disease Models, Animal; Endoplasmic Reticulum Stress; Gene Knockout Techniques; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucose Intolerance; Glucose Tolerance Test; Humans; Incretins; Injections, Subcutaneous; Insulin; Islets of Langerhans; Liraglutide; Male; Membrane Proteins; Rats; Rats, Transgenic; Treatment Outcome; Wolfram Syndrome | 2018 |
Glucose intolerance in monosodium glutamate obesity is linked to hyperglucagonemia and insulin resistance in α cells.
Topics: Adipose Tissue, White; Animals; Biomarkers; Blood Glucose; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Glucagon; Glucagon-Secreting Cells; Glucose Intolerance; Insulin; Insulin Resistance; Liver; Male; Mice; Obesity; Phosphoenolpyruvate Carboxykinase (ATP); Phosphorylation; Sodium Glutamate; TOR Serine-Threonine Kinases | 2019 |
Gastrointestinal motility in patients with end-stage renal disease on chronic hemodialysis.
Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Female; Gastric Emptying; Gastric Inhibitory Polypeptide; Gastrointestinal Motility; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Humans; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis | 2019 |
Hyperglucagonemia in youth is associated with high plasma free fatty acids, visceral adiposity, and impaired glucose tolerance.
Topics: Adiposity; Adolescent; Case-Control Studies; Cells, Cultured; Child; Cohort Studies; Cross-Sectional Studies; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Intolerance; Humans; Intra-Abdominal Fat; Islets of Langerhans; Male; Obesity, Abdominal; Pediatric Obesity; Up-Regulation | 2019 |
Tributyltin exposure disturbs hepatic glucose metabolism in male mice.
Topics: Animals; Blotting, Western; Fluorescent Antibody Technique; Glucagon; Glucagon-Secreting Cells; Gluconeogenesis; Glucose; Glucose Intolerance; Glucose Tolerance Test; Hyperinsulinism; Insulin-Secreting Cells; Liver; Male; Mice; Real-Time Polymerase Chain Reaction; Receptors, Glucagon; Trialkyltin Compounds | 2019 |
X-box binding protein 1 is essential for insulin regulation of pancreatic α-cell function.
Topics: Animals; DNA-Binding Proteins; Glucagon; Glucagon-Secreting Cells; Glucose Intolerance; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Knockout; Phosphorylation; Proto-Oncogene Proteins c-akt; Regulatory Factor X Transcription Factors; Signal Transduction; Transcription Factors; X-Box Binding Protein 1 | 2013 |
Glucose homeostasis, obesity and diabetes.
Topics: Aging; Body Mass Index; Diabetes Mellitus, Type 2; Glucagon; Glucose; Glucose Intolerance; Glucose Transport Proteins, Facilitative; Glycogen; Homeostasis; Humans; Inflammation Mediators; Insulin; Insulin Resistance; Metabolic Syndrome; Obesity; Obesity, Abdominal; Sodium-Glucose Transport Proteins | 2013 |
Evaluation of liver glycogen catabolism during hypercortisolism induced by the administration of dexamethasone in rats.
Topics: Animals; Body Weight; Cushing Syndrome; Cyclic AMP; Dexamethasone; Epinephrine; Fasting; Glucagon; Glucose Intolerance; Glycogen; Hyperglycemia; Liver; Male; Rats; Rats, Wistar | 2013 |
Beneficial effects of parenteral GLP-1 delivery by cell therapy in insulin-deficient streptozotocin diabetic mice.
Topics: Animals; Blood Glucose; Body Weight; Cell Line; Cell Transplantation; Diabetes Mellitus, Experimental; Eating; Female; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Insulin; Insulin-Secreting Cells; Male; Mice; Mice, SCID; Streptozocin | 2013 |
Fgf21 impairs adipocyte insulin sensitivity in mice fed a low-carbohydrate, high-fat ketogenic diet.
Topics: 3-Hydroxybutyric Acid; Adipocytes; Animals; Blood Glucose; Body Weight; Diet, Carbohydrate-Restricted; Diet, High-Fat; Fibroblast Growth Factors; Glucagon; Gluconeogenesis; Glucose Intolerance; Insulin; Insulin Resistance; Ketone Bodies; Liver; Male; Mice; Mice, Knockout; Phenotype; Phosphorylation; Proto-Oncogene Proteins c-akt | 2013 |
[Changes of plasma glucagon level in individuals with different glucose metabolism].
Topics: Diabetes Mellitus, Type 2; Glucagon; Glucose; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance | 2014 |
Hypothalamic prolyl endopeptidase (PREP) regulates pancreatic insulin and glucagon secretion in mice.
Topics: Animals; Blood Glucose; Gene Expression; Gene Knockdown Techniques; Glucagon; Glucose Clamp Technique; Glucose Intolerance; Hypothalamus; Indoles; Insulin; Insulin Secretion; Ion Channels; Male; Mice; Mice, Transgenic; Mitochondrial Proteins; Pancreas; Phosphorylation; Prolyl Oligopeptidases; Receptor, Insulin; Recombinant Proteins; Serine Endopeptidases; Serine Proteinase Inhibitors; Thiazolidines; Uncoupling Protein 1; Ventromedial Hypothalamic Nucleus | 2014 |
Meal feeding improves oral glucose tolerance in male rats and causes adaptations in postprandial islet hormone secretion that are independent of plasma incretins or glycemia.
Topics: Allostasis; Animals; Behavior, Animal; Feeding Behavior; Gastric Inhibitory Polypeptide; Glucagon; Glucose Intolerance; Hyperglycemia; Ileum; Incretins; Insulin; Insulin Secretion; Intestinal Mucosa; Islets of Langerhans; Jejunum; Male; Meals; Neurosecretory Systems; Organ Specificity; Postprandial Period; Proglucagon; Rats, Long-Evans | 2014 |
Over-expression of Follistatin-like 3 attenuates fat accumulation and improves insulin sensitivity in mice.
Topics: Activins; Adiposity; Animals; Diet, High-Fat; Female; Follistatin-Related Proteins; Glucagon; Glucose Intolerance; Insulin; Insulin Resistance; Islets of Langerhans; Liver; Mice, Inbred C57BL; Muscle Development; Muscle, Skeletal; Myostatin; Proteins; Random Allocation; Recombinant Proteins; Signal Transduction; Subcutaneous Fat; Up-Regulation | 2015 |
Patients with psoriasis are insulin resistant.
Topics: Adult; Anthropometry; Blood Glucose; C-Peptide; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Glucagon; Gluconeogenesis; Glucose Clamp Technique; Glucose Intolerance; Humans; Hyperinsulinism; Inflammation; Insulin; Insulin Resistance; Male; Middle Aged; Prediabetic State; Psoriasis; Risk | 2015 |
Increment of serum C-peptide measured by glucagon test closely correlates with human relative beta-cell area.
Topics: Aged; Blood Glucose; C-Peptide; Cell Count; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin Resistance; Insulin-Secreting Cells; Male; Middle Aged | 2015 |
Calcium release channel RyR2 regulates insulin release and glucose homeostasis.
Topics: Adult; Amino Acid Substitution; Animals; Calcium; Diabetes Mellitus, Type 2; Endoplasmic Reticulum Stress; Female; Glucagon; Glucose; Glucose Intolerance; Homeostasis; Humans; Insulin; Insulin Secretion; Ion Transport; Islets of Langerhans; Male; Mice, Obese; Mice, Transgenic; Mitochondria; Mutation, Missense; Nitrosation; Oxidation-Reduction; Point Mutation; Ryanodine Receptor Calcium Release Channel; Tachycardia, Ventricular; Young Adult | 2015 |
A Novel TGR5 Activator WB403 Promotes GLP-1 Secretion and Preserves Pancreatic β-Cells in Type 2 Diabetic Mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Glucose Tolerance Test; Insulin-Secreting Cells; Mice; Postprandial Period; Receptors, G-Protein-Coupled | 2015 |
Prediabetes linked to excess glucagon in transgenic mice with pancreatic active AKT1.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Enzyme Activation; Fasting; Genotype; Glucagon; Glucose; Glucose Intolerance; Homeostasis; Hyperglycemia; Insulin; Insulin Resistance; Mice; Mice, Transgenic; Myristic Acids; Pancreas; Prediabetic State; Proto-Oncogene Proteins c-akt | 2016 |
Acute disruption of glucagon secretion or action does not improve glucose tolerance in an insulin-deficient mouse model of diabetes.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diphtheria Toxin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Glucose Intolerance; Glucose Tolerance Test; Insulin; Insulin-Secreting Cells; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Glucagon; Streptozocin | 2016 |
Defective insulin secretion by chronic glucagon receptor activation in glucose intolerant mice.
Topics: Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Female; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Intolerance; Glucose Tolerance Test; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mice; Mice, Inbred C57BL; Receptors, Glucagon | 2016 |
Autophagy deficiency in β cells blunts incretin-induced suppression of glucagon release from α cells.
Topics: Animals; Autophagy; Diabetes Mellitus, Experimental; Glucagon; Glucagon-Secreting Cells; Glucose Intolerance; Incretins; Insulin-Secreting Cells; Islets of Langerhans; Male; Mice | 2015 |
Altered Plasma Levels of Glucagon, GLP-1 and Glicentin During OGTT in Adolescents With Obesity and Type 2 Diabetes.
Topics: Adolescent; Blood Glucose; Case-Control Studies; Child; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Glucose Tolerance Test; Humans; Male; Pediatric Obesity; Sweden | 2016 |
A Transient Metabolic Recovery from Early Life Glucose Intolerance in Cystic Fibrosis Ferrets Occurs During Pancreatic Remodeling.
Topics: Animals; Blood Glucose; Cystic Fibrosis; Cytokines; Female; Ferrets; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Hyperglycemia; Insulin; Insulin Resistance; Male; Pancreas | 2016 |
MitoNEET-Parkin Effects in Pancreatic α- and β-Cells, Cellular Survival, and Intrainsular Cross Talk.
Topics: Animals; Apoptosis; Cell Survival; Glucagon; Glucagon-Secreting Cells; Glucose; Glucose Intolerance; Hyperglycemia; Insulin; Insulin Secretion; Insulin-Secreting Cells; Iron-Binding Proteins; Membrane Proteins; Mice; Mitochondria; Receptor Cross-Talk; Ubiquitin-Protein Ligases | 2016 |
Acute Reduction of Incretin Effect and Glucose Intolerance in Rats by Single Intragastric Administration of 3-deoxyglucosone.
Topics: Animals; Cyclic AMP; Deoxyglucose; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Incretins; Insulin; Male; Mice; Prediabetic State; Rats | 2017 |
TSC1-mTOR signaling determines the differentiation of islet cells.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Blood Glucose; Cell Differentiation; Diet, High-Fat; Glucagon; Glucose Clamp Technique; Glucose Intolerance; Insulin; Insulin Resistance; Islets of Langerhans; Mice; Mice, Knockout; Nerve Tissue Proteins; Signal Transduction; Somatostatin; Telomerase; TOR Serine-Threonine Kinases | 2017 |
Brain GLUT4 Knockout Mice Have Impaired Glucose Tolerance, Decreased Insulin Sensitivity, and Impaired Hypoglycemic Counterregulation.
Topics: Animals; Blood Glucose; Blotting, Western; Brain; Diet, High-Fat; Epinephrine; Glucagon; Glucose; Glucose Clamp Technique; Glucose Intolerance; Glucose Tolerance Test; Glucose Transporter Type 4; Homeostasis; Hypoglycemia; Hypothalamus; In Vitro Techniques; Indinavir; Insulin Resistance; Male; Mice; Mice, Knockout; Neurons; Paraventricular Hypothalamic Nucleus; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley | 2017 |
Nonsuppressed Glucagon After Glucose Challenge as a Potential Predictor for Glucose Tolerance.
Topics: Adult; Aged; Cohort Studies; Diabetes Mellitus, Type 2; Diet Therapy; Exercise; Female; Finland; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin Resistance; Life Style; Longitudinal Studies; Male; Middle Aged | 2017 |
Determinants of the increase in ketone concentration during SGLT2 inhibition in NGT, IFG and T2DM patients.
Topics: Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Glucosides; Humans; Hypoglycemic Agents; Ketones; Male; Middle Aged; Sodium-Glucose Transporter 2 Inhibitors | 2017 |
Development and characterization of a novel rat model of type 2 diabetes mellitus: the UC Davis type 2 diabetes mellitus UCD-T2DM rat.
Topics: Adipokines; Adiposity; Age Factors; Aging; Animals; Blood Glucose; Crosses, Genetic; Diabetes Mellitus, Type 2; Disease Models, Animal; Disease Progression; Female; Fertility; Ghrelin; Glucagon; Glucose Intolerance; Insulin; Insulin Resistance; Insulin-Secreting Cells; Intra-Abdominal Fat; Lipids; Male; Obesity; Rats; Rats, Sprague-Dawley; Rats, Zucker; Triglycerides | 2008 |
Beta- and alpha-cell dysfunction in subjects developing impaired glucose tolerance: outcome of a 12-year prospective study in postmenopausal Caucasian women.
Topics: Aged; Arginine; Glucagon; Glucagon-Secreting Cells; Glucose Clamp Technique; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Middle Aged; Postmenopause; Prospective Studies; White People | 2009 |
Metabolic fate of plasma glucose during hyperglycemia in impaired glucose tolerance: evidence for further early defects in the pathogenesis of type 2 diabetes.
Topics: Alanine; Blood Glucose; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Clamp Technique; Glucose Intolerance; Glycogen; Glycolysis; Humans; Hyperglycemia; Lactic Acid; Male; Middle Aged; Oxidation-Reduction | 2009 |
Impaired insulin exocytosis in neural cell adhesion molecule-/- mice due to defective reorganization of the submembrane F-actin network.
Topics: Actins; Adenosine Triphosphate; Animals; Exocytosis; Female; Glucagon; Glucose; Glucose Intolerance; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Knockout; Neural Cell Adhesion Molecules; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying | 2009 |
Insulin signaling in alpha cells modulates glucagon secretion in vivo.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Fasting; Feeding Behavior; Gene Expression Regulation; Glucagon; Glucagon-Secreting Cells; Glucose Intolerance; Hyperinsulinism; Hypoglycemia; Insulin; Insulin-Secreting Cells; Mice; Mice, Knockout; Organ Size; Organ Specificity; Receptor, Insulin; Signal Transduction; Streptozocin | 2009 |
Chronic rapamycin treatment causes glucose intolerance and hyperlipidemia by upregulating hepatic gluconeogenesis and impairing lipid deposition in adipose tissue.
Topics: Adipocytes; Adipose Tissue; Animals; Blood Glucose; C-Peptide; Down-Regulation; Fatty Acids, Nonesterified; Glucagon; Glucose Intolerance; Hyperlipidemias; Immunosuppressive Agents; Insulin; Liver; Male; Mice; Muscle, Skeletal; Polymerase Chain Reaction; Pyruvates; Rats; Rats, Sprague-Dawley; RNA; Sirolimus; Triglycerides | 2010 |
Insulin sensitivity and body composition in cirrhosis: changes after TIPS.
Topics: Body Composition; C-Peptide; Diabetes Mellitus; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glucose Clamp Technique; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin Resistance; Liver; Liver Cirrhosis; Male; Middle Aged; Portasystemic Shunt, Transjugular Intrahepatic; Predictive Value of Tests; Rest | 2010 |
Glucagon-like peptide-2 receptor modulates islet adaptation to metabolic stress in the ob/ob mouse.
Topics: Adaptation, Physiological; Animals; Blood Glucose; Body Weight; Cell Proliferation; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptide-2 Receptor; Glucose Intolerance; Glucose Tolerance Test; Hypoglycemia; Insulin; Islets of Langerhans; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Receptors, Glucagon; Signal Transduction; Stress, Physiological; Time Factors | 2010 |
Chronic consumption of a high-fat/high-fructose diet renders the liver incapable of net hepatic glucose uptake.
Topics: Analysis of Variance; Animals; Area Under Curve; Biological Transport; Dietary Carbohydrates; Dietary Fats; Dogs; Fructose; Glucagon; Glucose; Glucose Clamp Technique; Glucose Intolerance; Glucose Tolerance Test; Liver; Male | 2010 |
Catalase rs769214 SNP in elderly malnutrition and during renutrition: is glucagon to blame?
Topics: Aged; Alleles; Binding Sites; Biomarkers, Pharmacological; Catalase; Computational Biology; DNA Mutational Analysis; Eye Proteins; Genetic Predisposition to Disease; Glucagon; Glucose Intolerance; Homeodomain Proteins; Humans; Malnutrition; Paired Box Transcription Factors; PAX6 Transcription Factor; Plasminogen Activator Inhibitor 1; Polymorphism, Single Nucleotide; Repressor Proteins; Transcriptional Activation; Tumor Necrosis Factor-alpha | 2011 |
Beta-cell uncoupling protein 2 regulates reactive oxygen species production, which influences both insulin and glucagon secretion.
Topics: Animals; Genes, Reporter; Glucagon; Glucagon-Secreting Cells; Glucose Intolerance; Humans; Hyperglycemia; Insulin; Insulin Secretion; Insulin-Secreting Cells; Ion Channels; Islets of Langerhans; Male; Membrane Potential, Mitochondrial; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Proteins; Organ Specificity; Promoter Regions, Genetic; Rats; Reactive Oxygen Species; Tissue Culture Techniques; Uncoupling Protein 2 | 2011 |
Lentivirus shRNA Grb10 targeting the pancreas induces apoptosis and improved glucose tolerance due to decreased plasma glucagon levels.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Caspase 3; Gene Expression Regulation; Gene Silencing; Glucagon; Glucagon-Secreting Cells; Glucose Intolerance; GRB10 Adaptor Protein; Injections; Insulin-Secreting Cells; Lentivirus; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Pancreas; Pancreatic Ducts; Proto-Oncogene Proteins; RNA, Messenger; RNA, Small Interfering; Signal Transduction | 2012 |
MK-626, a dipeptidyl peptidase-4 inhibitor, does not improve the hyperglycemia or hyperinsulinemia of nonobese diabetic MKR mice.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dipeptidyl-Peptidase IV Inhibitors; Glucagon; Glucose; Glucose Intolerance; Homeostasis; Hyperglycemia; Hyperinsulinism; Incretins; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Obese; Phenylalanine; Triazoles | 2012 |
NF-κB–inducing kinase (NIK) promotes hyperglycemia and glucose intolerance in obesity by augmenting glucagon action.
Topics: Animals; Cyclic AMP Response Element-Binding Protein; Glucagon; Glucose; Glucose Intolerance; Hyperglycemia; Liver; Male; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; NF-kappaB-Inducing Kinase; Obesity; Phosphorylation; Protein Serine-Threonine Kinases | 2012 |
Effects of long-term treatment with the dipeptidyl peptidase-4 inhibitor vildagliptin on islet endocrine cells in non-obese type 2 diabetic Goto-Kakizaki rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adamantane; Animals; Apoptosis; Cell Proliferation; Deoxyguanosine; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Eating; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Nitriles; Pyrrolidines; Rats; Time Factors; Vildagliptin | 2012 |
Abnormal endocrine pancreas function at birth in cystic fibrosis ferrets.
Topics: Animals; Animals, Newborn; Apoptosis; Cells, Cultured; Cystic Fibrosis; Diabetes Mellitus; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Female; Ferrets; Fibrosis; Gene Knockout Techniques; Glucagon; Glucose; Glucose Intolerance; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Male; Pancreas, Exocrine; Pancreatic Ducts; Pancreatitis; Species Specificity | 2012 |
In situ electrophysiological examination of pancreatic α cells in the streptozotocin-induced diabetes model, revealing the cellular basis of glucagon hypersecretion.
Topics: Action Potentials; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Electrophysiological Phenomena; Exocytosis; Glucagon; Glucagon-Secreting Cells; Glucose Intolerance; Hyperglycemia; Mice; Potassium Channels, Voltage-Gated; Secretory Vesicles; Voltage-Gated Sodium Channels | 2013 |
Impact of incretin on early-phase insulin secretion and glucose excursion.
Topics: Adult; Blood Glucose; Cohort Studies; Diabetes Mellitus, Type 2; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Glucose Tolerance Test; Humans; Incretins; Insulin; Insulin Secretion; Male; Middle Aged | 2013 |
Pathogenesis of prediabetes: role of the liver in isolated fasting hyperglycemia and combined fasting and postprandial hyperglycemia.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Carbon Isotopes; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Gluconeogenesis; Glucose Clamp Technique; Glucose Intolerance; Glycogenolysis; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Liver; Male; Middle Aged; Prediabetic State | 2013 |
Clofibrate improves glucose tolerance in fat-fed rats but decreases hepatic glucose consumption capacity.
Topics: Animal Feed; Animals; Blood Glucose; Body Temperature; Clofibrate; Dietary Fats; Eating; Fatty Acids, Nonesterified; Glucagon; Glucokinase; Glucose Intolerance; Glucose-6-Phosphatase; Glycogen; Hypolipidemic Agents; Insulin; Liver; Male; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Weight Gain | 2002 |
NN2211: a long-acting glucagon-like peptide-1 derivative with anti-diabetic effects in glucose-intolerant pigs.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Hypoglycemic Agents; Insulin; Liraglutide; Male; Peptide Fragments; Protein Precursors; Swine, Miniature | 2002 |
Beta cell neogenesis from ducts and phenotypic conversion of residual islet cells in the adult pancreas of glucose intolerant mice induced by selective alloxan perfusion.
Topics: Alloxan; Animals; Cell Differentiation; Cell Division; Glucagon; Glucose Intolerance; Homeobox Protein Nkx-2.2; Homeodomain Proteins; Immunohistochemistry; Insulin; Islets of Langerhans; Male; Mice; Mice, Inbred ICR; Microscopy, Electron; Pancreatic Ducts; Phenotype; Somatostatin; Trans-Activators | 2002 |
Increased dietary fat promotes islet amyloid formation and beta-cell secretory dysfunction in a transgenic mouse model of islet amyloid.
Topics: Amyloid; Animals; Blood Glucose; Body Weight; Dietary Fats; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Islet Amyloid Polypeptide; Islets of Langerhans; Male; Mice; Mice, Transgenic; Pancreatic Polypeptide; Somatostatin | 2003 |
Improved beta-cell function after standardized weight reduction in severely obese subjects.
Topics: Adult; Body Composition; Female; Glucagon; Glucose Intolerance; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Obesity, Morbid; Proinsulin; Weight Loss | 2003 |
[Optimal drug therapy of glucose intolerance is a guarantee of successful prevention of type 2 diabetes mellitus].
Topics: Acarbose; Adult; Age Factors; Aged; Blood Glucose; Body Mass Index; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Glucagon; Glucose; Glucose Intolerance; Humans; Hypoglycemic Agents; Insulin; Life Style; Middle Aged; Multicenter Studies as Topic; Placebos; Risk Factors; Smoking Prevention | 2002 |
Huntington's disease of the endocrine pancreas: insulin deficiency and diabetes mellitus due to impaired insulin gene expression.
Topics: Aging; Animals; Blood Glucose; Blotting, Northern; Blotting, Western; Calcium; Diabetes Mellitus; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Glucagon; Glucose Intolerance; Huntingtin Protein; Huntington Disease; Immunohistochemistry; Insulin; Islets of Langerhans; Mice; Mice, Transgenic; Nerve Tissue Proteins; Nuclear Proteins; RNA, Messenger; Somatostatin; Transcription Factors | 2002 |
Mechanisms for the deterioration in glucose tolerance associated with HIV protease inhibitor regimens.
Topics: Adipose Tissue; Adult; Blood Glucose; Body Composition; Body Constitution; C-Peptide; CD4 Lymphocyte Count; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Clamp Technique; Glucose Intolerance; Glycated Hemoglobin; Glycerol; HIV Infections; HIV Protease Inhibitors; Homeostasis; Humans; Insulin; Insulin Resistance; Islets of Langerhans; Lipids; Liver; Male; Middle Aged; Muscle, Skeletal; Proinsulin; Viral Load | 2003 |
Assessing the shape of the glucose curve during an oral glucose tolerance test.
Topics: Administration, Oral; Adult; Area Under Curve; Blood Glucose; Diabetes Mellitus; Fasting; Female; Germany; Glucagon; Glucose; Glucose Clamp Technique; Glucose Intolerance; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin; Kinetics; Male; Reference Values; Reproducibility of Results; White People | 2003 |
cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2.
Topics: Animals; Apoptosis; Cell Line; Cell Survival; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Diabetes Mellitus; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Intolerance; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin-Like Growth Factor I; Intracellular Signaling Peptides and Proteins; Islets of Langerhans; Mice; Mice, Transgenic; Peptide Fragments; Phosphoproteins; Phosphorylation; Promoter Regions, Genetic; Protein Precursors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Transfection; Transgenes; Tumor Cells, Cultured | 2003 |
Influence of acute hyperglycemia in human sepsis on inflammatory cytokine and counterregulatory hormone concentrations.
Topics: Acute Disease; Adult; Female; Glucagon; Glucose Intolerance; Hormones; Humans; Hydrocortisone; Hyperglycemia; Infections; Insulin; Interleukin-6; Male; Osmolar Concentration; Tumor Necrosis Factor-alpha | 2003 |
Insulin secretion and incretin hormones after oral glucose in non-obese subjects with impaired glucose tolerance.
Topics: Administration, Oral; Area Under Curve; Blood Glucose; Body Weight; C-Peptide; Case-Control Studies; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Liver; Middle Aged; Peptide Fragments; Protein Precursors; Regression Analysis; Time Factors | 2004 |
Characterization of beta-cell function impairment in first-degree relatives of type 2 diabetic subjects: modeling analysis of 24-h triple-meal tests.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Diet; Energy Intake; Family; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Clamp Technique; Glucose Intolerance; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Linear Models; Male; Models, Biological; Multivariate Analysis; Peptide Fragments; Protein Precursors | 2005 |
Pancreatic islet-specific expression of an insulin-like growth factor-I transgene compensates islet cell growth in growth hormone receptor gene-deficient mice.
Topics: Animals; Blood Glucose; Cell Division; Gene Expression; Glucagon; Glucose Intolerance; Homeodomain Proteins; Insulin; Insulin Secretion; Insulin-Like Growth Factor I; Islets of Langerhans; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Receptors, Somatotropin; Trans-Activators; Transgenes | 2005 |
Enhanced glucagon-like peptide-1 (GLP-1) response to oral glucose in glucose-intolerant HIV-infected patients on antiretroviral therapy.
Topics: Adult; Analysis of Variance; Antiretroviral Therapy, Highly Active; Antiviral Agents; Area Under Curve; Blood Glucose; Body Composition; C-Peptide; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Intolerance; Glucose Tolerance Test; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Male; Peptide Fragments; Protein Precursors | 2005 |
Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth.
Topics: Animals; Blood Glucose; Cell Proliferation; Cyclin D1; Cyclin D2; Cyclins; Diabetes Mellitus; Gene Expression; Glucagon; Glucose Intolerance; Insulin; Islets of Langerhans; Male; Mice; Mice, Knockout | 2005 |
The effect of global SSTR5 gene ablation on the endocrine pancreas and glucose regulation in aging mice.
Topics: Aging; Animals; Blood Glucose; Body Weight; Female; Glucagon; Glucose; Glucose Intolerance; Glucose Tolerance Test; Growth Disorders; Immunohistochemistry; Insulin; Insulin Secretion; Islets of Langerhans; Male; Metabolic Clearance Rate; Mice; Mice, Knockout; Receptors, Somatostatin | 2005 |
Impact of glucagon response on postprandial hyperglycemia in men with impaired glucose tolerance and type 2 diabetes mellitus.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Fats; Dietary Proteins; Fasting; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Multivariate Analysis; Postprandial Period | 2005 |
Differences of pancreatic expression of 7B2 between C57BL/6J and C3H/HeJ mice and genetic polymorphisms at its locus (Sgne1).
Topics: Aging; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Gene Expression Regulation; Glucagon; Glucose Intolerance; Humans; Islets of Langerhans; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Molecular Sequence Data; Neuroendocrine Secretory Protein 7B2; Pancreas; Polymorphism, Genetic; Promoter Regions, Genetic; Proprotein Convertase 2; Protein Folding; Sequence Alignment | 2006 |
Long-term administration of PACAP receptor antagonist, PACAP(6-27), impairs glucose tolerance and insulin sensitivity in obese diabetic ob/ob mice.
Topics: Animals; Body Weight; Diabetes Mellitus; Eating; Feeding Behavior; Glucagon; Glucose Intolerance; Insulin; Lipids; Mice; Mice, Obese; Obesity; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Time Factors | 2006 |
Pathogenesis of pre-diabetes: mechanisms of fasting and postprandial hyperglycemia in people with impaired fasting glucose and/or impaired glucose tolerance.
Topics: Blood Glucose; C-Peptide; Fasting; Female; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Insulin Secretion; Kinetics; Male; Middle Aged; Postprandial Period; Prediabetic State; Reference Values | 2006 |
Evaluation of pancreatic endocrine and exocrine function in patients with autoimmune pancreatitis.
Topics: Adult; Aged; Autoimmune Diseases; Bicarbonates; Constriction, Pathologic; Diabetes Mellitus; Female; Fibrosis; Glucagon; Glucose Intolerance; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Pancreas, Exocrine; Pancreatic Ducts; Pancreatitis, Chronic; Secretin | 2007 |
Contribution of hepatic and extrahepatic insulin resistance to the pathogenesis of impaired fasting glucose: role of increased rates of gluconeogenesis.
Topics: Adipose Tissue; Blood Glucose; Body Mass Index; C-Peptide; Fasting; Female; Glucagon; Gluconeogenesis; Glucose Intolerance; Humans; Hyperglycemia; Insulin Resistance; Liver; Male; Middle Aged; Reference Values | 2007 |
Glucagon as a determinant of fibrinolytic activity in men with different stages of glucose tolerance: impact of glucagon on fibrinolysis.
Topics: Aged; Area Under Curve; Diabetes Mellitus, Type 2; Fibrinolysis; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin Resistance; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Tissue Plasminogen Activator | 2007 |
Chemical gastric inhibitory polypeptide receptor antagonism protects against obesity, insulin resistance, glucose intolerance and associated disturbances in mice fed high-fat and cafeteria diets.
Topics: Adiponectin; Animals; Blood Glucose; Body Weight; Corticosterone; Dietary Fats; Eating; Gastric Inhibitory Polypeptide; Glucagon; Glucose Intolerance; Glycated Hemoglobin; Insulin; Insulin Resistance; Lipids; Locomotion; Male; Mice; Mice, Obese; Obesity; Receptors, Gastrointestinal Hormone | 2007 |
GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet.
Topics: Adipokines; Adipose Tissue; Animals; Anti-Obesity Agents; Blood Glucose; Body Weight; Corticosterone; Dietary Fats; Eating; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Incretins; Insulin; Insulin Resistance; Lipids; Liver; Male; Mice; Motor Activity; Muscle, Skeletal; Obesity; Pancreas; Receptors, Gastrointestinal Hormone | 2007 |
Reduced blood glucose levels, increased insulin levels and improved glucose tolerance in alpha2A-adrenoceptor knockout mice.
Topics: Adrenergic beta-Antagonists; Animals; Atropine; Blood Glucose; Corticosterone; Fasting; Female; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Insulin; Insulin-Secreting Cells; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscarinic Antagonists; Propranolol; Receptors, Adrenergic, alpha-2; Time Factors | 2008 |
Predictors of incretin concentrations in subjects with normal, impaired, and diabetic glucose tolerance.
Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Intolerance; Glucose Tolerance Test; Humans; Incretins; Male; Middle Aged; Triglycerides | 2008 |
Chronic calcific pancreatitis of the tropics (CCPT): spectrum and correlates of exocrine and endocrine pancreatic dysfunction.
Topics: Adolescent; Adult; Age of Onset; Analysis of Variance; Blood Glucose; C-Peptide; Calcinosis; Chronic Disease; Chymotrypsin; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Islets of Langerhans; Male; Pancreas; Pancreatitis; Reference Values; Tropical Climate; Ultrasonography | 1995 |
Peripheral and hepatic insulin sensitivity in subjects with impaired glucose tolerance.
Topics: Blood Glucose; C-Peptide; Deuterium; Glucagon; Glucose; Glucose Clamp Technique; Glucose Intolerance; Glucose Tolerance Test; Humans; Infusions, Intravenous; Insulin; Insulin Secretion; Liver; Male; Middle Aged; Radioisotope Dilution Technique; Reference Values; Somatostatin | 1995 |
Amylin alters the biological action of the incretin hormone GLP-1(7-36)amide.
Topics: Adenylyl Cyclases; Amyloid; Animals; Cell Line; Colforsin; Cyclic AMP; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Intolerance; Insulinoma; Islet Amyloid Polypeptide; Islets of Langerhans; Models, Biological; Peptide Fragments; Peptides; Rats; Substance P | 1993 |
Feedback inhibition of insulin and glucagon secretion by insulin is altered in abdominal obesity with normal or impaired glucose tolerance.
Topics: Adult; Blood Glucose; C-Peptide; Feedback; Female; Glucagon; Glucose Clamp Technique; Glucose Intolerance; Humans; Insulin; Insulin Secretion; Male; Obesity; Reference Values | 1993 |
[Experimental study on the metabolism of pancreatic hormone in obstructive jaundice].
Topics: Animals; Cholestasis; Dogs; Glucagon; Glucose Intolerance; Insulin; Pancreas; Sincalide | 1994 |
beta-cell function and glucose and lipid oxidation in Graves' disease.
Topics: Adult; Aged; Blood Glucose; Calorimetry, Indirect; Female; Glucagon; Glucose Intolerance; Graves Disease; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Lipid Peroxidation; Male; Middle Aged; Norepinephrine; Proinsulin; Thyroid Hormones | 1996 |
Oral sensory stimulation improves glucose tolerance in humans: effects on insulin, C-peptide, and glucagon.
Topics: Adult; Blood Glucose; C-Peptide; Glucagon; Glucose; Glucose Intolerance; Humans; Insulin; Intubation, Gastrointestinal; Male; Mouth; Sensation; Stimulation, Chemical | 1996 |
Determinants of a normal (versus impaired) oral glucose tolerance after combined pancreas-kidney transplantation in IDDM patients.
Topics: Adult; alpha-Amylases; Analysis of Variance; Biomarkers; Blood Glucose; Blood Group Incompatibility; C-Peptide; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Follow-Up Studies; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Graft Rejection; Graft Survival; Histocompatibility Testing; Humans; Immunosuppressive Agents; Insulin; Insulin Secretion; Kidney Transplantation; Male; Pancreas Transplantation; Reference Values; Regression Analysis; Time Factors | 1996 |
Failure to adequately adapt reduced insulin sensitivity with increased insulin secretion in women with impaired glucose tolerance.
Topics: Arginine; Blood Glucose; Body Mass Index; Female; Glucagon; Glucose Clamp Technique; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Middle Aged; Normal Distribution; Random Allocation | 1996 |
Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene.
Topics: Animals; Blood Glucose; Female; Gene Deletion; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose; Glucose Intolerance; Insulin; Male; Mice; Peptide Fragments; Protein Precursors; Rats; Receptors, Glucagon | 1996 |
Abnormal myocardial kinetics of 123I-heptadecanoic acid in subjects with impaired glucose tolerance.
Topics: Adult; Analysis of Variance; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Echocardiography; Fatty Acids; Fatty Acids, Nonesterified; Glucagon; Glucose Intolerance; Heart; Humans; Iodine Radioisotopes; Male; Middle Aged; Models, Cardiovascular; Myocardium; Reference Values; Tissue Distribution; Tomography, Emission-Computed; Ventricular Function, Left | 1997 |
Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat.
Topics: Animals; Apoptosis; Cohort Studies; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Glucagon; Glucose; Glucose Intolerance; Glucose Tolerance Test; Immunohistochemistry; In Vitro Techniques; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Pancreatic Polypeptide; Perfusion; Rats; Rats, Zucker; Somatostatin; Time Factors | 1998 |
beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes.
Topics: Amyloid; Animals; Blood Glucose; Cell Line; Diabetes Mellitus, Type 2; Gene Expression Regulation; Genes; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Glucose Transporter Type 2; Heterozygote; Homeodomain Proteins; Immunohistochemistry; Insulin; Islet Amyloid Polypeptide; Islets of Langerhans; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Mutant Strains; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Phenotype; Trans-Activators; Transcriptional Activation | 1998 |
Glucagon-like peptide 1 improves the ability of the beta-cell to sense and respond to glucose in subjects with impaired glucose tolerance.
Topics: Administration, Oral; Adult; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Intolerance; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Peptide Fragments; Protein Precursors | 1998 |
Somatostatin release in response to glucose is impaired in chronic renal failure.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Female; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Kidney Failure, Chronic; Male; Middle Aged; Somatostatin; Uremia | 1998 |
The ageing entero-insular axis.
Topics: Acetaminophen; Adult; Aged; Aging; Blood Glucose; Body Mass Index; Body Weight; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Intolerance; Humans; Insulin; Insulin Secretion; Peptide Fragments; Postmenopause; Premenopause; Risk Factors | 1998 |
Impact of lack of suppression of glucagon on glucose tolerance in humans.
Topics: Adult; Blood Glucose; C-Peptide; Carbon Dioxide; Female; Glucagon; Glucose; Glucose Intolerance; Human Growth Hormone; Humans; Insulin; Male | 1999 |
All patients with Werner's syndrome are insulin resistant, but only those who also have impaired insulin secretion develop overt diabetes.
Topics: Consanguinity; Female; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin Resistance; Male; Pedigree; Werner Syndrome | 1999 |
Glucose intolerance caused by a defect in the entero-insular axis: a study in gastric inhibitory polypeptide receptor knockout mice.
Topics: Administration, Oral; Animals; Diabetes Mellitus, Type 2; Dietary Fats; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Intolerance; Glucose Tolerance Test; Homeostasis; Injections, Intraperitoneal; Insulin; Insulin Resistance; Insulin Secretion; Intestines; Islets of Langerhans; Mice; Mice, Knockout; Models, Biological; Peptide Fragments; Protein Precursors; Receptors, Gastrointestinal Hormone | 1999 |
Glucose intolerance is predicted by low insulin secretion and high glucagon secretion: outcome of a prospective study in postmenopausal Caucasian women.
Topics: Analysis of Variance; Arginine; Body Constitution; Cohort Studies; Female; Follow-Up Studies; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Middle Aged; Postmenopause; Predictive Value of Tests; Prospective Studies; Regression Analysis; Sweden; Time Factors; White People | 2000 |
PAC1 receptor-deficient mice display impaired insulinotropic response to glucose and reduced glucose tolerance.
Topics: Animals; Blood Glucose; Brain; Cyclic AMP; Female; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Insulin; Mice; Mice, Mutant Strains; Neuropeptides; Pancreas; Perfusion; Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I; Receptors, Pituitary Hormone; Receptors, Vasoactive Intestinal Peptide, Type II; Vasoactive Intestinal Peptide | 2000 |
Islet dysfunction in insulin resistance involves impaired insulin secretion and increased glucagon secretion in postmenopausal women with impaired glucose tolerance.
Topics: Blood Pressure; Body Composition; Body Constitution; Body Mass Index; Female; Glucagon; Glucose Clamp Technique; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Middle Aged; Postmenopause | 2000 |
Characterisation of beta-cell dysfunction of impaired glucose tolerance: evidence for impairment of incretin-induced insulin secretion.
Topics: Adult; Arginine; Blood Glucose; C-Peptide; Fasting; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Glucose Intolerance; Glycated Hemoglobin; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Peptide Fragments; Reference Values | 2000 |
Reduced GLP-1 and insulin responses and glucose intolerance after gastric glucose in GRP receptor-deleted mice.
Topics: Animals; Blood Glucose; Enzyme-Linked Immunosorbent Assay; Female; Gastric Lavage; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Intolerance; Insulin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Protein Precursors; Receptors, Bombesin | 2000 |
Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats.
Topics: Aging; Animals; Blood Glucose; Cell Division; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Homeodomain Proteins; Insulin; Islets of Langerhans; Pancreas; Peptide Fragments; Protein Precursors; Rats; Rats, Wistar; Trans-Activators | 2000 |
Monounsaturated fatty acid diets improve glycemic tolerance through increased secretion of glucagon-like peptide-1.
Topics: Administration, Oral; Animals; Body Weight; Cell Line; Dietary Fats; Duodenum; Eating; Fatty Acids; Fatty Acids, Monounsaturated; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Glucose Tolerance Test; Male; Oleic Acid; Palmitic Acid; Peptide Fragments; Protein Precursors; Rats; Rats, Zucker | 2001 |
Evidence against a rate-limiting role of proinsulin processing for maximal insulin secretion in subjects with impaired glucose tolerance and beta-cell dysfunction.
Topics: Adult; Arginine; Blood Glucose; Female; Glucagon; Glucagon-Like Peptide 1; Glucose Clamp Technique; Glucose Intolerance; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Middle Aged; Peptide Fragments; Proinsulin; Protein Precursors | 2001 |
Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients.
Topics: Analysis of Variance; Autoantibodies; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Fasting; Fatty Acids, Nonesterified; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Glutamate Decarboxylase; Glycated Hemoglobin; Humans; Insulin; Male; Middle Aged; Pancreatic Polypeptide; Peptide Fragments; Peptides; Protein Precursors; Reference Values | 2001 |
Beta-cell-targeted expression of a dominant-negative hepatocyte nuclear factor-1 alpha induces a maturity-onset diabetes of the young (MODY)3-like phenotype in transgenic mice.
Topics: Animals; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Female; Gene Expression; Gene Targeting; Genes, Dominant; Glucagon; Glucose Intolerance; Glucose Transporter Type 2; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Insulin; Insulin Antagonists; Islets of Langerhans; Male; Mice; Mice, Transgenic; Monosaccharide Transport Proteins; Mutation; Nuclear Proteins; Pancreas; Phenotype; Sex Characteristics; Transcription Factors | 2001 |
Impaired glucose tolerance (IGT) is associated with reduced insulin-induced suppression of glucagon concentrations.
Topics: Area Under Curve; Body Mass Index; Cholesterol; Female; Glucagon; Glucose Clamp Technique; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Middle Aged; Postmenopause; Reference Values; Sweden; Triglycerides; White People | 2001 |
Long-term inhibition of dipeptidyl peptidase IV improves glucose tolerance and preserves islet function in mice.
Topics: Animals; Blood Glucose; Body Weight; Dietary Fats; Dipeptidyl Peptidase 4; Drinking; Eating; Female; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Intolerance; Insulin; Insulin Resistance; Intubation, Gastrointestinal; Islets of Langerhans; Mice; Mice, Inbred C57BL; Nitriles; Organ Size; Peptide Fragments; Protease Inhibitors; Protein Precursors; Pyrrolidines; Time Factors | 2002 |