Page last updated: 2024-09-04

glucagon and Genetic Predisposition

glucagon has been researched along with Genetic Predisposition in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.88)18.2507
2000's5 (29.41)29.6817
2010's11 (64.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Auwerx, J; Dongiovanni, P; Kim, K; Nayak, S; Ozcan, L; Pajvani, UB; Ryu, D; Ueberheide, B; Valenti, L1
Hamada, S; Masamune, A; Nabeshima, T; Shimosegawa, T; Taguchi, K; Yamamoto, M1
Feng, T; Gao, K; Hu, D; Li, C; Li, L; Ren, Y; Wang, B; Wang, C; Wang, J; Wang, Q; Wang, Y; Yin, L; You, H; Zhai, Y; Zhao, J1
Charron, MJ; Du, XQ; Foda, ZH; Kleiner, RE; Leissring, MA; Liu, DR; Maianti, JP; McFedries, A; Saghatelian, A; Seeliger, MA; Tang, WJ1
Gao, K; Hu, D; Li, L; Ren, Y; Wang, B; Wang, J; Wang, Q; Wang, Y; Yan, G; You, H; Zhai, Y; Zhang, J; Zhang, M1
Gao, K; Hu, D; Li, L; Luo, X; Wang, C; Wang, J; Zhang, J; Zhang, M; Zhao, J1
Fritsche, A; Häring, HU; Machicao, F; Staiger, H1
Spellman, CW1
Damm, P; Nolan, CJ; Prentki, M1
Beaudeux, JL; Cottart, CH; Cynober, L; Fabre, EE; Golmard, JL; Hebert-Schuster, M; Laguillier-Morizot, C; Nivet-Antoine, V; Raynaud-Simon, A1
Hitman, GA1
Cobelli, C; Dalla Man, C; Micheletto, F; Sathananthan, A; Sathananthan, M; Smushkin, G; Vella, A; Zinsmeister, AR1
Hjorth, SA; Jensen, AD; Vilsbøll, T; Ørskov, C1
Herzig, S1
Chen, S; Grayburn, P; Orci, L; Ravazzola, M; Unger, RH; Wang, MY1
Jacob, HJ; Koike, G; Maget, B; Rivière, M; Shiozawa, M; Simon, JS; Svoboda, M; Szpirer, C; Szpirer, J; Vanvooren, P1
Cherrington, AD; Dixon, K; Fujimoto, Y; Grimsby, J; Grippo, JF; Jetton, TL; Magnuson, MA; Pan, D; Postic, C; Shiota, M1

Reviews

4 review(s) available for glucagon and Genetic Predisposition

ArticleYear
Pathomechanisms of type 2 diabetes genes.
    Endocrine reviews, 2009, Volume: 30, Issue:6

    Topics: Adiposity; Animals; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Glucagon; Humans; Insulin; Insulin Secretion; Polymorphism, Single Nucleotide

2009
Pathophysiology of type 2 diabetes: targeting islet cell dysfunction.
    The Journal of the American Osteopathic Association, 2010, Volume: 110, Issue:3 Suppl 2

    Topics: Blood Glucose; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Disease Progression; Endocrine Cells; Genetic Predisposition to Disease; Global Health; Glucagon; Glucose; Humans; Incidence; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Risk Assessment

2010
Type 2 diabetes across generations: from pathophysiology to prevention and management.
    Lancet (London, England), 2011, Jul-09, Volume: 378, Issue:9786

    Topics: Adipose Tissue; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Diabetes, Gestational; Diabetic Retinopathy; Epigenesis, Genetic; Female; Fetal Development; Genetic Predisposition to Disease; Glucagon; Glucagon-Like Peptide 1; Homeostasis; Humans; Incretins; Insulin Resistance; Insulin-Secreting Cells; Life Style; Liver; Muscle, Skeletal; Myocardium; Obesity; Prediabetic State; Pregnancy

2011
[Transcription factors and metabolic diseases].
    Deutsche medizinische Wochenschrift (1946), 2007, May-18, Volume: 132, Issue:20

    Topics: Cholesterol; Genetic Predisposition to Disease; Glucagon; Gluconeogenesis; Humans; Liver; Metabolic Syndrome; Transcription Factors

2007

Other Studies

13 other study(ies) available for glucagon and Genetic Predisposition

ArticleYear
Degradation of PHLPP2 by KCTD17, via a Glucagon-Dependent Pathway, Promotes Hepatic Steatosis.
    Gastroenterology, 2017, Volume: 153, Issue:6

    Topics: Adaptor Proteins, Signal Transducing; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Genetic Predisposition to Disease; Glucagon; Hep G2 Cells; Humans; Lipogenesis; Liver; Liver Neoplasms; Male; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Obesity; Phenotype; Phosphoprotein Phosphatases; Phosphorylation; Proteolysis; Signal Transduction

2017
Simultaneous K-ras activation and Keap1 deletion cause atrophy of pancreatic parenchyma.
    American journal of physiology. Gastrointestinal and liver physiology, 2018, 01-01, Volume: 314, Issue:1

    Topics: Animals; Atrophy; Blood Glucose; Disease Models, Animal; Female; Gene Deletion; Genes, p53; Genes, ras; Genetic Predisposition to Disease; Glucagon; Homeodomain Proteins; Insulin; Integrases; Kelch-Like ECH-Associated Protein 1; Male; Mice, Knockout; Mutation; NF-E2-Related Factor 2; Pancreas; Pancreatitis, Chronic; Parenchymal Tissue; Phenotype; Trans-Activators

2018
Glucagon gene polymorphism modifies the effects of smoking and physical activity on risk of type 2 diabetes mellitus in Han Chinese.
    Gene, 2014, Jan-25, Volume: 534, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Alleles; Asian People; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Glucagon; Humans; Male; Middle Aged; Motor Activity; Polymorphism, Single Nucleotide; Risk; Smoking; Young Adult

2014
Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones.
    Nature, 2014, Jul-03, Volume: 511, Issue:7507

    Topics: Animals; Binding Sites; Blood Glucose; Catalytic Domain; Diabetes Mellitus, Type 2; Disease Models, Animal; Gastric Emptying; Genetic Predisposition to Disease; Glucagon; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Insulysin; Islet Amyloid Polypeptide; Macrocyclic Compounds; Male; Mice; Mice, Inbred C57BL; Models, Molecular; Obesity; Signal Transduction; Thinness

2014
Association of LRP5, TCF7L2, and GCG variants and type 2 diabetes mellitus as well as fasting plasma glucose and lipid metabolism indexes.
    Human immunology, 2015, Volume: 76, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Case-Control Studies; China; Diabetes Mellitus, Type 2; DNA Mutational Analysis; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Glucagon; Humans; Lipid Metabolism; Low Density Lipoprotein Receptor-Related Protein-5; Male; Middle Aged; Polymorphism, Single Nucleotide; Risk; Severity of Illness Index; Transcription Factor 7-Like 2 Protein; Triglycerides; Wnt Signaling Pathway; Young Adult

2015
Association of Canonical Wnt/β-Catenin Pathway and Type 2 Diabetes: Genetic Epidemiological Study in Han Chinese.
    Nutrients, 2015, Jun-15, Volume: 7, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alleles; Asian People; beta Catenin; Body Mass Index; Case-Control Studies; China; Diabetes Mellitus, Type 2; Female; Genetic Predisposition to Disease; Genotyping Techniques; Glucagon; Haplotypes; Humans; Linkage Disequilibrium; Logistic Models; Low Density Lipoprotein Receptor-Related Protein-5; Male; Middle Aged; Polymorphism, Single Nucleotide; Transcription Factor 7-Like 2 Protein; Wnt Signaling Pathway; Young Adult

2015
Catalase rs769214 SNP in elderly malnutrition and during renutrition: is glucagon to blame?
    Free radical biology & medicine, 2011, Oct-15, Volume: 51, Issue:8

    Topics: Aged; Alleles; Binding Sites; Biomarkers, Pharmacological; Catalase; Computational Biology; DNA Mutational Analysis; Eye Proteins; Genetic Predisposition to Disease; Glucagon; Glucose Intolerance; Homeodomain Proteins; Humans; Malnutrition; Paired Box Transcription Factors; PAX6 Transcription Factor; Plasminogen Activator Inhibitor 1; Polymorphism, Single Nucleotide; Repressor Proteins; Transcriptional Activation; Tumor Necrosis Factor-alpha

2011
The message for MODY.
    Diabetic medicine : a journal of the British Diabetic Association, 2011, Volume: 28, Issue:9

    Topics: Autoantibodies; C-Peptide; Creatinine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Genetic Predisposition to Disease; Glucagon; Glutamate Decarboxylase; Glycated Hemoglobin; Humans; Immunologic Factors; Male; Mutation; RNA, Messenger; Transcription, Genetic

2011
Diabetes-associated common genetic variation and its association with GLP-1 concentrations and response to exogenous GLP-1.
    Diabetes, 2012, Volume: 61, Issue:5

    Topics: C-Peptide; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Genetic Variation; Genotype; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Clamp Technique; Humans; Hyperglycemia; Insulin; Insulin-Secreting Cells; KCNQ1 Potassium Channel; Membrane Proteins; Transcription Factor 7-Like 2 Protein

2012
Typical Danish Caucasian type 2 diabetic patients do not commonly carry genetic variants in GIP and GLP-1 encoding regions of the proGIP and proglucagon genes.
    Regulatory peptides, 2004, Jul-15, Volume: 119, Issue:3

    Topics: Aged; Base Sequence; Denmark; Diabetes Mellitus, Type 2; DNA; Female; Gastric Inhibitory Polypeptide; Genetic Predisposition to Disease; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Humans; Male; Middle Aged; Molecular Sequence Data; Peptide Fragments; Phenotype; Polymerase Chain Reaction; Predictive Value of Tests; Protein Precursors; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Sequence Analysis, DNA; White People

2004
Adipogenic capacity and the susceptibility to type 2 diabetes and metabolic syndrome.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Apr-22, Volume: 105, Issue:16

    Topics: Adipocytes; Adipogenesis; Adipose Tissue; Animals; Calcium-Binding Proteins; Cardiomyopathies; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Glucagon; Insulin; Intercellular Signaling Peptides and Proteins; Metabolic Syndrome; Mice; Mice, Transgenic; Obesity; Pancreas; Promoter Regions, Genetic; Receptors, Leptin; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Transgenes

2008
Localization of the rat genes encoding glucagon, glucagon receptor, and insulin receptor, candidates for diabetes mellitus susceptibility loci.
    Mammalian genome : official journal of the International Mammalian Genome Society, 1997, Volume: 8, Issue:8

    Topics: Animals; Chromosome Mapping; Diabetes Mellitus; Diabetes Mellitus, Type 2; DNA Probes; Genetic Markers; Genetic Predisposition to Disease; Glucagon; In Situ Hybridization, Fluorescence; Rats; Receptor, Insulin; Receptors, Glucagon

1997
Glucokinase gene locus transgenic mice are resistant to the development of obesity-induced type 2 diabetes.
    Diabetes, 2001, Volume: 50, Issue:3

    Topics: Animals; Blood Glucose; Chromosome Mapping; Diabetes Mellitus, Type 2; Dietary Fats; Genetic Predisposition to Disease; Glucagon; Glucokinase; Insulin; Liver; Mice; Mice, Transgenic; Obesity; Reference Values; RNA, Messenger; Transgenes

2001