Page last updated: 2024-09-04

glucagon and Fatty Liver, Nonalcoholic

glucagon has been researched along with Fatty Liver, Nonalcoholic in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's18 (52.94)24.3611
2020's16 (47.06)2.80

Authors

AuthorsStudies
Feigh, M; Harris, MS; Nestor, JJ; Parkes, D; Suschak, JJ1
Elmelund, E; Galsgaard, KD; Holst, JJ; Kjeldsen, SAS; Knop, FK; Richter, MM; Suppli, MP; Wewer Albrechtsen, NJ; Winther-Sørensen, M1
Perry, RJ1
Ahlström, H; Bergsten, P; Forslund, A; Kullberg, J; Manell, H; Mangge, H; Maruszczak, K; Mörwald, K; Pixner, T; Radzikowski, K; Schütz, S; Weghuber, D1
Holst, JJ; Wewer Albrechtsen, NJ; Winther-Sørensen, M1
Andreassen, KV; Henriksen, K; Karsdal, MA; Kayed, A; Khan, S; Melander, SA1
Kardassis, D; Thymiakou, E; Tzardi, M1
Biondi, G; Caruso, I; Cignarelli, A; D'Oria, R; Genchi, VA; Giorgino, F; Laviola, L; Marrano, N; Natalicchio, A; Perrini, S; Sorice, GP1
Bartlett, PJ; Brumer, RP; Corrêa-Velloso, JC; Sandiford, OA; Thomas, AP; Thomas, SJ1
Bloom, SR; Campbell, JE; Cherrington, AD; Dean, ED; Finan, B; Gluud, LL; Holst, JJ; Knop, FK; Müller, TD; Tan, TM; Wewer Albrechtsen, NJ1
Brill, AL; Butrico, GM; Cline, GW; Dufour, S; Ehrlich, BE; Goedeke, L; Guerra, MT; Nasiri, AR; Nathanson, MH; Nozaki, Y; Peng, L; Perry, RJ; Petersen, KF; Rabin-Court, A; Shulman, GI; Toussaint, K; Wang, Y; Zhang, D; Zhang, XM; Zhang, Y1
Matsuda, K; Moritoh, Y; Ookawara, M; Watanabe, M1
Fappi, A; Mittendorfer, B1
Andersen, DB; Bisgaard, HC; Dall, M; Eriksen, PL; Galsgaard, KD; Gillum, MP; Gluud, LL; Hassing, AS; Holst, JJ; Hunt, JE; Jepsen, SL; Kjeldsen, SAS; Knop, FK; Kuhre, RE; Pedersen, J; Santos, A; Sulek, K; Torekov, SS; Trammell, SAJ; Treebak, JT; Vasilopoulou, CG; Vilstrup, H; Werge, MP; Wewer Albrechtsen, NJ; Windeløv, JA; Winther-Sørensen, M; Ørskov, C1
Adamski, J; Gar, C; Haschka, SJ; Holst, JJ; Kern-Matschilles, S; Lechner, A; Prehn, C; Rauch, B; Sacco, V; Seissler, J; Wewer Albrechtsen, NJ1
Chen, C; Chen, X; Chen, Y; Lin, Z; Lu, Y; Wan, H; Wang, C; Wang, N; Wang, Y; Xia, F; Zhang, W1
Geisler, CE; Renquist, BJ1
Junker, AE1
Auwerx, J; Dongiovanni, P; Kim, K; Nayak, S; Ozcan, L; Pajvani, UB; Ryu, D; Ueberheide, B; Valenti, L1
Christensen, M; Galsgaard, KD; Holst, JJ; Hædersdal, S; Junker, AE; Knop, FK; Lund, AM; Vilsbøll, T; Wewer Albrechtsen, NJ; Wibrand, F1
Bahekar, R; Jain, M; Joharapurkar, A; Kadam, S; Kshirsagar, S; Pandey, D; Patel, D; Patel, H; Patel, M; Patel, V; Ranvir, R; Sutariya, B1
Eckel, RH; Koh, KK; Lim, S1
Bao, L; Gao, W; Gao, X; Wang, Q; Yao, W; Yin, J1
Choi, D; Jung, CH; Kang, SK; Kim, BY; Kim, CH; Lee, B; Moh Moh, MA; Mok, JO1
Huang, F; Wang, T; Xia, J; Yao, W; Zhang, L1
Anděl, M; Červinková, Z; Fontana, J1
Beglinger, C; Bernsmeier, C; Blaser, LS; Heim, MH; Jeker, L; Meyer-Gerspach, AC; Steinert, RE1
Rui, L1
Hao, L; Huang, KH; Ito, K; Lambert, JD; Ross, AC; Sae-tan, S1
Gluud, LL; Holst, JJ; Junker, AE; Knop, FK; van Hall, G; Vilsbøll, T1
Gluud, L; Holst, JJ; Junker, AE; Knop, FK; Vilsbøll, T1
Agius, L1
Holst, JJ; Knop, FK; Kuhre, RE; Pedersen, J; Wewer Albrechtsen, NJ1
Biebermann, H; Brandt, S; Clemmensen, C; De Angelis, M; DiMarchi, R; Döring, Y; Finan, B; Fischer, K; Flamant, F; Fuchs, H; Gailus-Durner, V; Gauthier, K; Gelfanov, V; Habegger, KM; Healy, ME; Heikenwalder, M; Hofmann, SM; Hrabě de Angelis, M; Jall, S; Jastroch, M; Keuper, M; Kleinert, M; Köhrle, J; Liu, F; Liu, P; Lutter, D; Malehmir, M; Moreth, K; Müller, L; Müller, TD; Neff, F; Perez-Tilve, D; Rozman, J; Sánchez-Garrido, MA; Schramm, KW; Stemmer, K; Tschöp, MH; Tuckermann, J; Weber, A; Weber, C; Yang, B; Zhu, Z1

Reviews

14 review(s) available for glucagon and Fatty Liver, Nonalcoholic

ArticleYear
The Liver-α-Cell Axis in Health and in Disease.
    Diabetes, 2022, 09-01, Volume: 71, Issue:9

    Topics: Amino Acids; Blood Glucose; Diabetes Mellitus, Type 2; Glucagon; Glucose; Hepatocytes; Humans; Insulin; Non-alcoholic Fatty Liver Disease

2022
Regulation of Hepatic Lipid and Glucose Metabolism by INSP3R1.
    Diabetes, 2022, 09-01, Volume: 71, Issue:9

    Topics: Calcium; Diabetes Mellitus, Type 2; Glucagon; Glucose; Humans; Inositol 1,4,5-Trisphosphate Receptors; Lipid Metabolism; Lipids; Liver; Non-alcoholic Fatty Liver Disease

2022
The feedback cycles between glucose, amino acids and lipids and alpha cell secretion and their role in metabolic fatty liver disease.
    Current opinion in lipidology, 2023, 02-01, Volume: 34, Issue:1

    Topics: Amino Acids; Animals; Diabetes Mellitus, Type 2; Feedback; Glucagon; Glucose; Humans; Hyperglycemia; Lipids; Non-alcoholic Fatty Liver Disease

2023
Glucagon in type 2 diabetes: Friend or foe?
    Diabetes/metabolism research and reviews, 2023, Volume: 39, Issue:3

    Topics: Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucose; Humans; Hypoglycemic Agents; Non-alcoholic Fatty Liver Disease

2023
100 years of glucagon and 100 more.
    Diabetologia, 2023, Volume: 66, Issue:8

    Topics: Amino Acids; Diabetes Mellitus, Type 2; Glucagon; Glucose; Humans; Hyperglycemia; Non-alcoholic Fatty Liver Disease

2023
Dietary protein intake and obesity-associated cardiometabolic function.
    Current opinion in clinical nutrition and metabolic care, 2020, Volume: 23, Issue:6

    Topics: Animals; Blood Glucose; Cardiometabolic Risk Factors; Cardiovascular Diseases; Cholesterol; Diabetes Mellitus, Type 2; Diet, High-Protein; Diet, High-Protein Low-Carbohydrate; Dietary Proteins; Glucagon; Humans; Insulin; Non-alcoholic Fatty Liver Disease; Obesity; Triglycerides

2020
Hepatic lipid accumulation: cause and consequence of dysregulated glucoregulatory hormones.
    The Journal of endocrinology, 2017, Volume: 234, Issue:1

    Topics: Adipose Tissue; Animals; Diet; Endocrine System Diseases; Fatty Liver; Glucagon; Gluconeogenesis; Glucose; Homeostasis; Hormones; Humans; Hydrocortisone; Hyperinsulinism; Lipid Metabolism; Lipids; Lipogenesis; Lipolysis; Liver; Non-alcoholic Fatty Liver Disease; Obesity; Overnutrition; Oxidation-Reduction; Signal Transduction; Virus Diseases

2017
The role of incretin hormones and glucagon in patients with liver disease.
    Danish medical journal, 2017, Volume: 64, Issue:5

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose Intolerance; Humans; Incretins; Insulin; Liver; Mice; Non-alcoholic Fatty Liver Disease

2017
Clinical implications of current cardiovascular outcome trials with sodium glucose cotransporter-2 (SGLT2) inhibitors.
    Atherosclerosis, 2018, Volume: 272

    Topics: Albuminuria; Atherosclerosis; Benzhydryl Compounds; Body Weight; Canagliflozin; Cardiovascular Diseases; Cardiovascular System; Glucagon; Glucagon-Like Peptides; Glucosides; Heart Failure; Hemodynamics; Humans; Hypoglycemic Agents; Ketones; Lipids; Liraglutide; Metabolic Syndrome; Metformin; Non-alcoholic Fatty Liver Disease; Osmosis; Risk Factors; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Treatment Outcome

2018
Glucagon-Induced Acetylation of Energy-Sensing Factors in Control of Hepatic Metabolism.
    International journal of molecular sciences, 2019, Apr-16, Volume: 20, Issue:8

    Topics: Acetylation; Animals; Energy Metabolism; Fasting; Glucagon; Glucose; Homeostasis; Humans; Lipid Metabolism; Liver; Liver Neoplasms; Non-alcoholic Fatty Liver Disease

2019
[Effects of GLP-1 (glucagon-like peptide 1) on liver].
    Vnitrni lekarstvi, 2013, Volume: 59, Issue:7

    Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Hepatocytes; Humans; Hypoglycemic Agents; Incretins; Insulin; Lipid Metabolism; Liver Diseases; Non-alcoholic Fatty Liver Disease; Oxidative Stress

2013
Energy metabolism in the liver.
    Comprehensive Physiology, 2014, Volume: 4, Issue:1

    Topics: Circadian Rhythm; Cytokines; Diabetes Mellitus, Type 2; Endoplasmic Reticulum; Energy Metabolism; Fatty Acids; Glucagon; Gluconeogenesis; Glucose; Human Growth Hormone; Humans; Insulin; Lipogenesis; Liver; Non-alcoholic Fatty Liver Disease; Obesity

2014
Hormonal and Metabolite Regulation of Hepatic Glucokinase.
    Annual review of nutrition, 2016, 07-17, Volume: 36

    Topics: Adaptor Proteins, Signal Transducing; Animals; Diabetes Mellitus, Type 2; Gene Expression Regulation, Enzymologic; Glucagon; Glucokinase; Homeostasis; Humans; Liver; Models, Biological; Non-alcoholic Fatty Liver Disease; Phosphofructokinase-2; Postprandial Period; Protein Transport

2016
The biology of glucagon and the consequences of hyperglucagonemia.
    Biomarkers in medicine, 2016, Volume: 10, Issue:11

    Topics: Diabetes Mellitus; Glucagon; Glucagon-Like Peptide 1; Glucagonoma; Humans; Liver; Neoplasms; Non-alcoholic Fatty Liver Disease; Oxyntomodulin; Pancreas; Receptors, Glucagon

2016

Trials

1 trial(s) available for glucagon and Fatty Liver, Nonalcoholic

ArticleYear
Diabetic and nondiabetic patients with nonalcoholic fatty liver disease have an impaired incretin effect and fasting hyperglucagonaemia.
    Journal of internal medicine, 2016, Volume: 279, Issue:5

    Topics: Adult; Blood Glucose; C-Reactive Protein; Diabetes Mellitus, Type 2; Fasting; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Humans; Incretins; Insulin; Male; Middle Aged; Non-alcoholic Fatty Liver Disease

2016

Other Studies

19 other study(ies) available for glucagon and Fatty Liver, Nonalcoholic

ArticleYear
Effects of ALT-801, a GLP-1 and glucagon receptor dual agonist, in a translational mouse model of non-alcoholic steatohepatitis.
    Scientific reports, 2022, 04-23, Volume: 12, Issue:1

    Topics: Animals; Cholesterol; Collagen; Disease Models, Animal; Galectin 3; Glucagon; Glucagon-Like Peptide 1; Inflammation; Interleukin-2; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Non-alcoholic Fatty Liver Disease; Obesity; Receptors, Antigen, T-Cell; Receptors, Glucagon; Recombinant Fusion Proteins; Transaminases; Triglycerides

2022
Determinants of hyperglucagonemia in pediatric non-alcoholic fatty liver disease.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adolescent; Child; Glucagon; Glucose; Glycated Hemoglobin; Humans; Insulin; Insulin Resistance; Non-alcoholic Fatty Liver Disease; Obesity; Triglycerides; Uric Acid

2022
The Effects of Dual GLP-1/Glucagon Receptor Agonists with Different Receptor Selectivity in Mouse Models of Obesity and Nonalcoholic Steatohepatitis.
    The Journal of pharmacology and experimental therapeutics, 2023, Volume: 384, Issue:3

    Topics: Animals; Body Weight; Complement C4; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Lipids; Mice; Non-alcoholic Fatty Liver Disease; Obesity; Receptors, Glucagon

2023
Impaired hepatic glucose metabolism and liver-α-cell axis in mice with liver-specific ablation of the Hepatocyte Nuclear Factor 4α (Hnf4a) gene.
    Metabolism: clinical and experimental, 2023, Volume: 139

    Topics: Animals; Glucagon; Glucose; Hepatocyte Nuclear Factor 4; Hepatocyte Nuclear Factors; Insulin; Liver; Mice; Mice, Knockout; Non-alcoholic Fatty Liver Disease

2023
Short-term high-fat diet feeding of mice suppresses catecholamine-stimulated Ca
    The Journal of physiology, 2023, Volume: 601, Issue:8

    Topics: Animals; Catecholamines; Diabetes Mellitus, Type 2; Diet, High-Fat; Glucagon; Hepatocytes; Inositol 1,4,5-Trisphosphate; Liver; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Norepinephrine

2023
Glucagon stimulates gluconeogenesis by INSP3R1-mediated hepatic lipolysis.
    Nature, 2020, Volume: 579, Issue:7798

    Topics: Acetyl Coenzyme A; Adipose Tissue; Animals; Diabetes Mellitus, Type 2; Enzyme Activation; Glucagon; Gluconeogenesis; Inositol 1,4,5-Trisphosphate Receptors; Lipase; Lipolysis; Liver; Mice, Knockout; Mitochondria; Non-alcoholic Fatty Liver Disease; Oxidation-Reduction

2020
The GPR40 Full Agonist SCO-267 Improves Liver Parameters in a Mouse Model of Nonalcoholic Fatty Liver Disease without Affecting Glucose or Body Weight.
    The Journal of pharmacology and experimental therapeutics, 2020, Volume: 375, Issue:1

    Topics: Administration, Oral; Animals; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucose; Liver; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Receptors, G-Protein-Coupled; Triglycerides

2020
Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis.
    Molecular metabolism, 2020, Volume: 42

    Topics: Adult; Amino Acids; Animals; Blood Glucose; Fatty Liver; Female; Glucagon; Glucagon-Secreting Cells; Glucose; Hepatocytes; Humans; Insulin; Insulin Resistance; Liver; Male; Mice; Mice, Inbred C57BL; Middle Aged; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; Receptors, Glucagon; Urea

2020
The liver-alpha cell axis associates with liver fat and insulin resistance: a validation study in women with non-steatotic liver fat levels.
    Diabetologia, 2021, Volume: 64, Issue:3

    Topics: Adiposity; Adult; Alanine; Biomarkers; Blood Chemical Analysis; Cross-Sectional Studies; Female; Glucagon; Glucagon-Secreting Cells; Humans; Insulin Resistance; Liver; Magnetic Resonance Imaging; Non-alcoholic Fatty Liver Disease; Predictive Value of Tests; Prognosis; Prospective Studies

2021
Glucagon is associated with NAFLD inflammatory progression in type 2 diabetes, not with NAFLD fibrotic progression.
    European journal of gastroenterology & hepatology, 2021, 12-01, Volume: 33, Issue:1S Suppl 1

    Topics: Adult; China; Diabetes Mellitus, Type 2; Glucagon; Humans; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease

2021
Degradation of PHLPP2 by KCTD17, via a Glucagon-Dependent Pathway, Promotes Hepatic Steatosis.
    Gastroenterology, 2017, Volume: 153, Issue:6

    Topics: Adaptor Proteins, Signal Transducing; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Genetic Predisposition to Disease; Glucagon; Hep G2 Cells; Humans; Lipogenesis; Liver; Liver Neoplasms; Male; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Obesity; Phenotype; Phosphoprotein Phosphatases; Phosphorylation; Proteolysis; Signal Transduction

2017
Hyperglucagonemia correlates with plasma levels of non-branched-chain amino acids in patients with liver disease independent of type 2 diabetes.
    American journal of physiology. Gastrointestinal and liver physiology, 2018, 01-01, Volume: 314, Issue:1

    Topics: Adult; Aged; Amino Acids; Biomarkers; Body Mass Index; Case-Control Studies; Cholesterol; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Glucagon-Secreting Cells; Glycated Hemoglobin; Humans; Insulin Resistance; Liver; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Up-Regulation

2018
Coagonist of glucagon-like peptide-1 and glucagon receptors ameliorates nonalcoholic fatty liver disease.
    Canadian journal of physiology and pharmacology, 2018, Volume: 96, Issue:6

    Topics: Animals; Exenatide; Glucagon; Glucagon-Like Peptide 1; Liver; Male; Mice; Non-alcoholic Fatty Liver Disease; Peptides; Receptors, Glucagon; Venoms

2018
A long-acting FGF21 alleviates hepatic steatosis and inflammation in a mouse model of non-alcoholic steatohepatitis partly through an FGF21-adiponectin-IL17A pathway.
    British journal of pharmacology, 2018, Volume: 175, Issue:16

    Topics: Adiponectin; Animals; Anti-Inflammatory Agents; Blood Glucose; Body Weight; Delayed-Action Preparations; Disease Models, Animal; Fibroblast Growth Factors; Glucagon; Insulin; Interleukin-17; Lipids; Liver; Male; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Signal Transduction

2018
Association of glucagon-to-insulin ratio and nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus.
    Diabetes & vascular disease research, 2019, Volume: 16, Issue:2

    Topics: Adiposity; Adult; Aged; Biomarkers; Body Mass Index; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Prevalence; Prognosis; Republic of Korea; Risk Assessment; Risk Factors; Time Factors; Ultrasonography

2019
Glucose-induced glucagon-like Peptide 1 secretion is deficient in patients with non-alcoholic fatty liver disease.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Case-Control Studies; Fatty Liver; Female; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Non-alcoholic Fatty Liver Disease

2014
Shifts in dietary carbohydrate-lipid exposure regulate expression of the non-alcoholic fatty liver disease-associated gene PNPLA3/adiponutrin in mouse liver and HepG2 human liver cells.
    Metabolism: clinical and experimental, 2014, Volume: 63, Issue:10

    Topics: Animals; Cell Line, Tumor; Diet, High-Fat; Dietary Carbohydrates; Fatty Liver; Gene Expression; Glucagon; Glucose; Hep G2 Cells; Hepatocytes; Humans; Insulin; Lipid Metabolism; Lipids; Lipogenesis; Liver; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease

2014
Effects of glucagon-like peptide-1 on glucagon secretion in patients with non-alcoholic fatty liver disease.
    Journal of hepatology, 2016, Volume: 64, Issue:4

    Topics: Adult; Aged; Energy Metabolism; Female; Glucagon; Glucagon-Like Peptide 1; Glucose; Humans; Insulin; Insulin Secretion; Lipolysis; Liver; Male; Middle Aged; Non-alcoholic Fatty Liver Disease

2016
Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease.
    Cell, 2016, Oct-20, Volume: 167, Issue:3

    Topics: Animals; Atherosclerosis; Body Weight; Bone and Bones; Chemical Engineering; Cholesterol; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Combinations; Drug Delivery Systems; Drug Synergism; Glucagon; Hyperglycemia; Liver; Metabolic Diseases; Mice; Molecular Targeted Therapy; Non-alcoholic Fatty Liver Disease; Obesity; Triiodothyronine

2016