glucagon has been researched along with Disease Models, Animal in 326 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 91 (27.91) | 18.7374 |
1990's | 41 (12.58) | 18.2507 |
2000's | 69 (21.17) | 29.6817 |
2010's | 99 (30.37) | 24.3611 |
2020's | 26 (7.98) | 2.80 |
Authors | Studies |
---|---|
Cheng, M; Fu, CL; Li, XL; Xu, M; Yu, F; Yu, X | 1 |
Fougner, AL; Lopez-Zazueta, C; Stavdahl, O | 1 |
Feigh, M; Harris, MS; Nestor, JJ; Parkes, D; Suschak, JJ | 1 |
Chen, A; DePaoli, A; Fanget, M; Fox, M; Guo, W; Haldankar, R; Humphrey, M; Kaplan, DD; Kekatpure, A; Kutach, A; Li, D; Lindhout, DA; Liu, W; Liu, Z; Matern, H; Mondal, K; Ngan, I; Pedersen, O; Shen, D; Solloway, MJ; Song, B; Tang, J; Tian, H; Wang, Y; Winans, B; Wu, H; Xi, Y; Yang, H; Younis, H; Zha, J; Zhou, M | 1 |
Biancolin, AD; Brubaker, PL; Jeong, H; Mak, KWY; Yuan, Z | 1 |
Åkertröm, T; Bouman, SD; Bowler, A; Brand, CL; Cappelen, KA; Demozay, D; Egebjerg, T; Eliasen, IP; Hansen, BF; Hennen, S; Hoeg-Jensen, T; Hummelshøj, T; Hvid, H; Ingvorsen, C; Jensen, S; McGuire, J; Olsen, GS; Pedersen, TÅ; Poulsen, BR; Roed, NK; Stidsen, CE; Tiainen, P | 1 |
Andreassen, KV; Henriksen, K; Karsdal, MA; Kayed, A; Khan, S; Melander, SA | 1 |
Caicedo, A; Panzer, JK | 1 |
Andrés, A; de Solís, AJ; Fernández, A; Gallardo, N; López, V; Mazuecos, L; Pintado, C; Rodríguez, M; Rubio, B | 1 |
Li, P; Liu, BL; Liu, Q; Ma, G; Pan, A; Qi, LW; Ying, A; Zhang, WS; Zhang, X | 1 |
Cardone, RL; Cravatt, BF; Gillum, MP; Grevengoed, TJ; Kibbey, RG; Knop, FK; McKinney, MK; Nexøe-Larsen, CC; Ogasawara, D; Petersen, N; Schwartz, TW; Svenningsen, JS; Trammell, SAJ | 1 |
Andersen, B; Bokhari, MH; Busby, O; Cannon, B; Conde-Frieboes, KW; Fels, JJ; Nedergaard, J; Paulsson, JF; Rakipovski, G; Raun, K; Zouhar, P | 1 |
Cao, T; Carmichael, GG; Diano, S; Huang, X; Huang, Y; Jin, S; Sun, X; Taylor, HS; Yang, X | 1 |
Azhar, S; Bittner, A; Bittner, S; Chan, J; Cortez, Y; Dong, D; Han, L; Kraemer, FB; Peterson, RG; Shen, WJ; Umar, M | 1 |
Coulter, CE; DuVall, MA; Gosey, JL; Herrera, MJ; Hill, CM; Maisano, LE; McDougal, DH; Morrison, CD; Sikaffy, HX | 1 |
Abbasnezhad, A; Abd El-Ghafar, OA; Abhilash, L; Abouzid, KAM; Achberger, AM; Ackerman, S; Akhatayeva, Z; Akin, D; Al-Kaysi, RO; Alakhdar, AA; Alame, M; Aleksic Sabo, V; Alinezhadbalalami, N; Allen, JD; Alonso, JM; Alqatani, S; Alsayed, B; Álvarez Larraondo, M; Alvarez, M; Amini, SB; An, Z; Anasir, MI; Anderson, GH; Andremont, A; Andrés, S; Angel, S; Anigboro, AA; Anini, Y; Antonides, CFJ; Arafa, K; Arafa, RK; Aryal, UK; Asbaghi, O; Assefa, MK; Atyah, M; Avwioroko, OJ; Ayora-Talavera, G; Azpilikueta, A; Azyazov, VN; Ba, YF; Bachmann, KF; Badoual, J; Bae, SJ; Baek, SH; Bahrami, B; Bai, J; Baid-Agrawal, S; Bailey, MR; Baillie, JK; Balani, N; Balcar, VJ; Banica, T; Banks, L; Barb, J; Bardeen, CJ; Barrett, HE; Bartnikowski, N; Bashir, R; Battaglia, M; Bautista-Hernández, V; Becker, B; Beekman, FJ; Benidir, M; Benjelloun, M; Bentley, RF; Bergé, J; Berger, D; Bernsen, MR; Berraondo, P; Bhattacharya, R; Bhayani, SB; Bi, W; Bi, X; Bi, YL; Bi, Z; Bian, K; Biesecker, LG; Billadeau, DD; Blaszczyk, R; Blum, JL; Boachie, R; Boelte, K; Bogers, AJJC; Boileau, I; Bonduelle, C; Bonny, O; Bonsu, JM; Boos, LA; Borges-Argáez, R; Bouchard, PA; Boudot, C; Bourgeade-Delmas, S; Boutet-Robinet, E; Boyle, AJ; Branigan, D; Briones, S; Broniowska, KA; Brossas, JY; Brown, WA; Brzezinska, J; Buitron, G; Burnier, M; Bursulaya, B; Burton, PR; Bush, AA; Busuttil, RW; Cabello-Aguilar, S; Cáceres-Farfán, M; Cacheux, V; Caffrey, PJ; Cai, B; Cai, Q; Cai, S; Cai, Y; Calders, P; Cammarota, G; Campbell, DA; Cancelli, C; Cao, Q; Cao, WH; Cao, X; Capet, M; Capoluongo, E; Carey, ME; Carnero, M; Carrasco, LI; Carreno, J; Carrillo-Reyes, J; Casini, I; Cassar, M; Catalan, G; Cattamanchi, A; Cazares-Granillo, M; Celie, B; Cen, YK; Cena, H; Cerbo, RM; Ceron, E; Cetina-Montejo, L; Chaâbane-Banaoues, R; Chabanet, C; Chace-Donahue, F; Chalfun-Júnior, A; Chan-Balan, R; Chang, CS; Chen, CS; Chen, D; Chen, J; Chen, L; Chen, PN; Chen, Q; Chen, S; Chen, W; Chen, WP; Chen, X; Chen, Z; Cheng, H; Cheng, J; Cheng, Q; Cheng, T; Chi, T; Chianelli, D; Chieppa, M; Child, CJ; Cho, JH; Cho, JY; Chogtu, B; Choi, GH; Choi, J; Choi, M; Choi, NG; Cholu, CO; Chow, ES; Chowdhury, AH; Chu, PC; Chu, Q; Chu, S; Chua, H; Chung, T; Chunyan, L; Church, JS; Civardi, E; Cobiella, J; Colinge, J; Collado, CJ; Collins, TJ; Cong, LM; Conkrite, KL; Cope, SJ; Corbett, JA; Cornet, M; Cornillot, E; Corvaisier, S; Costes-Martineau, V; Courtioux, B; Coussens, M; Covino, M; Criado, A; Cui, J; Cui, Y; Cunitz, BW; Curry, AE; Cussó, L; D'Urzo, AD; D'Urzo, KA; Dabbous, S; Dahlgren, RA; Dai, H; Dai, T; Dai, W; Dalinghaus, M; Dang, S; Davalos, RV; Davidson, H; de Andrea, CE; De Angelis, M; de Blois, E; de Carvalho, PA; De Clercq, E; De Giuseppe, R; de Jong, M; De Langhe, S; De Oliveira, L; de Souza Pinto Lemgruber, R; de Souza, LB; de Swart, J; De Wandele, I; de Woestijne, PCV; Delaney, S; Delorme, M; Delvenne, P; Deng, L; Deng, Z; Denkinger, CM; der Meulen, MHV; Deraeve, C; Desco, M; DeSilva, S; Destere, A; Dhali, A; Di Ciano, P; Dias-Santagata, D; Diskin, SJ; Djè, MK; Doddipatla, S; Doerr, AJ; Dokla, EME; Domiciano, D; Domingo, N; Dong, C; Dong, J; Dong, Q; Dong, S; Dong, X; Dong, Z; Douair, I; Douglas, TA; Doyle, SM; Drain, PK; Du, K; Du, L; Du, Q; Du, S; Duan, C; Duan, H; Duan, J; Duan, S; Duan, W; Dueluzeau, R; Dukic, L; Dunmire, BL; Duvauchelle, T; Dymek, B; Dzwonek, K; Earnest, A; Eckardt, KU; El Ghadraoui, L; El Massoudi, S; Elloumi, F; Elnour, IE; Embarak, S; Ende, M; England, K; Enikeev, D; Enyedy, I; Epple, R; Erickson, GE; Eriksson, J; Erndt-Marino, J; Errachidi, F; Etxeberria, I; Evan, AP; Fairlamb, AH; Falahi, E; Fan, CC; Fan, H; Fan, M; Fan, MZ; Fan, S; Fan, Y; Fang, CS; Fang, J; Fang, X; Fang, Z; Farmany, A; Farooqi, A; Farouk, HO; Fazelipour, S; Feng, D; Feng, J; Feng, JX; Feng, YL; Ferraz, SL; Ferreira, CR; Figenshau, RS; Finn, AV; Fiseha, T; Fleischer, AS; Fogleman, AD; Fontaine, O; Ford, CR; Fouladvand, F; Four, M; Fousteri, G; Francis, JR; Fraser, JF; Frazier, RP; Fu, H; Fu, P; Fu, YJ; Fujishima, A; Fuster, V; Gabilan, JC; Gagliani, N; Gai, QY; Galán-Arriola, C; Gale, P; Galimova, GR; Galkin, A; Gallo, A; Gallo, AA; Gang, DD; Ganschow, S; Gao, C; Gao, F; Gao, GP; Gao, H; Gao, K; Gao, M; Gao, MY; Gao, P; Gao, R; Gao, S; Gao, WJ; Gao, Y; Garbacz, P; García Ruiz, L; Garcia, EM; Garofoli, F; Gasbarrini, A; Gattinoni, L; Gaudig, M; Gbureck, U; Ge, X; Genko, N; Gentile, GL; George, MW; Gerety, GF; Gestwicki, JE; Geusens, PP; Ghassemi, M; Giardina, JD; Giebultowicz, JM; Gifford, CA; Gijsen, FJH; Gilfillan, R; Gilson, E; Gingl, K; Giuliano, C; Glybochko, P; Goessler, W; Gofflot, S; Golab, J; Goldstein, A; Golebiowski, A; Gómez, L; Gómez-Carballo, J; Gonçalves, PEO; Gonzales, R; Gonzalez-Cotto, M; González-Fernández, D; Gonzalez-Lopez de Turiso, F; Goodman, JM; Govinda Raju, S; Grimm, J; Gross, AJ; Gruenheid, S; Gu, C; Gu, FF; Gu, S; Gu, Z; Guest, RL; Gui, C; Gui, J; Guillem, A; Guo, G; Guo, L; Guo, Q; Guo, S; Guo, SW; Guo, W; Guo, Y; Guo, YG; Guo, Z; Guretzky, JA; Haenggi, M; Hahn, MS; Hakkola, J; Halim, AA; Hampel, D; Han, B; Han, BH; Han, D; Han, G; Han, J; Han, LZ; Han, R; Han, S; Han, X; Han, Z; Handley, MA; Hanke, I; Hannongbua, S; Hao, P; Happ, JT; Hara, M; Haraux, F; Hare, JL; Harper, JD; Hartley, AM; Harvey, E; Hashimoto, K; Hassan, HM; Hautajärvi, H; Hayton, TW; He, C; He, H; He, HJ; He, WP; He, Y; He, Z; Hedrick, V; Heffernan, JK; Hegrová, J; Heidarimoghadam, R; Helms, K; Hengphasatporn, K; Henry, D; Herrmann, TRW; Hesson, T; Himmelbauer, MK; Hindle, A; Hoffmann, R; Hogg, N; Hong, KB; Hong, SK; Honjol, Y; Hood, C; Hsi, RS; Hsu, JL; Hu, B; Hu, BC; Hu, D; Hu, H; Hu, J; Hu, K; Hu, M; Hu, MK; Hu, T; Hu, W; Hu, Y; Hu, Z; Hua, S; Huang, H; Huang, J; Huang, L; Huang, M; Huang, P; Huang, X; Huang, Y; Huang, Z; Hukkanen, J; Hung, MC; Huo, X; Hyötyläinen, T; Ianiro, G; Ibanez, B; Imran, M; Ireland, S; Irwin, MS; Ishiguro, H; Jackowski, K; Jackson, C; Jacob, SI; Jahromy, MH; Jakob, SM; Jang, J; Javvaji, PK; Jefferson, KK; Jena, P; Ji, H; Jiang, F; Jiang, GH; Jiang, H; Jiang, J; Jiang, X; Jiang, Z; Jiao, J; Jiménez, A; Jin, X; Jincai, W; Jintao, X; Jo, K; Jofra, T; Johari, Y; Johnson, ACM; Jones, JH; Josephine Fauci, A; Juhl, AK; Jun, S; Kaiser, RI; Kajioka, J; Kajiyama, H; Kalliyil, A; Kalthur, SG; Kamalanathan, M; Kamaldinov, T; Kanaani, L; Kang, D; Kang, J; Kang, S; Känsäkoski, P; Kaplan, DL; Karwan, M; Kasibhatla, S; Kaur, A; Kawazoe, Y; Ke, C; Keyser, J; Khalique, A; Khan, IT; Kharshoum, RM; Kher, R; Kherani, J; Ki, KK; Kikkawa, F; Kikkawa, R; Kim, BT; Kim, EH; Kim, GA; Kim, GD; Kim, HB; Kim, HG; Kim, JS; Kim, MJ; Kim, SI; Kim, SJ; Kim, Y; King, K; Kinyamu-Akunda, J; Kirkkala, T; Kjaer-Sorensen, K; Kleppinger, EL; Kloner, RA; Klopfenstein, TJ; Knappe, D; Knezevic, P; Kobos, LM; Kohli, M; Kolano, L; Kolodgie, FD; Kolte, AP; Koneru, B; Kong, D; Kong, F; Kong, X; Konggidinata, MI; Köpke, M; Koski, KG; Kotsis, F; Köttgen, A; Kouakou-Kouamé, CA; Kraemer, US; Krane, V; Krehbiel, CR; Krenning, BJ; Kretzschmar, D; Ku, KB; Kubota, Y; Kulich, P; Kumar, NG; Kupiec-Weglinski, JW; Lalani, SS; Lan, X; Landfeldt, E; Langenberg, E; Lapauw, B; Larkin, J; Lassoued, MA; Laukhtina, E; Laura Martinez, J; Laveillé, A; Lavela, P; Law, AD; Lazraq, A; Le Foll, B; Lee, BK; Lee, C; Lee, CS; Lee, EJ; Lee, EY; Lee, G; Lee, HY; Lee, JH; Lee, JJ; Lee, JO; Lee, JS; Lee, R; Lei, H; Lei, P; Lellouche, F; Lennerz, JK; Leong, W; Leslie, I; Lessem, E; Levin, M; Levinger, I; Li, C; Li, CW; Li, CX; Li, CY; Li, D; Li, H; Li, HM; Li, J; Li, L; Li, LM; Li, N; Li, S; Li, W; Li, X; Li, XX; Li, Y; Li, Z; Li, ZL; Li, ZX; Lian, Q; Liang, C; Liang, GH; Liang, H; Liang, J; Liang, X; Liao, CX; Liao, R; Ličbinský, R; Lim, YS; Lima, HK; Lin, JG; Lin, L; Lin, S; Lin, WP; Lin, Z; Liso, M; Liu, BX; Liu, C; Liu, H; Liu, J; Liu, M; Liu, Q; Liu, S; Liu, SF; Liu, SL; Liu, T; Liu, W; Liu, X; Liu, XB; Liu, Y; Liu, YY; Liu, Z; Liu, ZQ; Lobo, M; Loitzenbauer, M; López, F; Lopez, G; López, GJ; Lou, Z; Lu, IC; Lu, J; Lu, M; Lu, W; Lu, X; Lu, Y; Luhovyy, BL; Luna-Abanto, J; Luo, J; Luo, K; Luo, L; Luo, M; Luo, W; Luo, X; Luo, XM; Lv, Y; Lv, YQ; Lyu, HD; Lyu, J; Ma, C; Ma, G; Ma, L; Ma, Q; Ma, X; Ma, Y; Macha, SJ; MacLean, E; Mahalapbutr, P; Maina, T; Malfait, F; Malfertheiner, MV; Malzert-Fréon, A; Mansouri, E; Mao, C; Marcellin, E; Marchiori, PER; Marcotte, DJ; Maréchal, A; Maric, N; Maris, JM; Maron, L; Marti, CN; Martínez-Milla, J; Mateo, J; Mather, K; Mathison, CJN; Matthay, MA; Maxwell, CL; Mazier, D; Mazumder, D; Mazurkiewicz, M; Mazzucchelli, TG; McAuley, DF; Mccoy, K; McVicar, DW; Mebel, AM; Mech, A; Meester, EJ; Meiselbach, H; Melero, I; Ménard, G; Meng, X; Mengya, Y; Merle, G; Meunier, B; Mfarrej, B; Mi, K; Migueliz, I; Mikuška, P; Miladi, K; Miletich, R; Millar, JE; Mills, MR; Milne, R; Minute, L; Misiak, M; Mo, F; Modi, A; Mok, F; Molina, C; Mollen, CJ; Molteni, V; Montalto, M; Montet, D; Monti, MC; Moor, MB; Moravec, P; Morsiani, C; Murillo, E; Murugan, P; Muslem, R; Myers, RK; N'guessan, FK; Nabil, H; Nadal, J; Nadeem, M; Nafady, MM; Nafie, MS; Nair, HP; Nakano, R; Nance, J; Naren, N; Neil, CJ; Nelson, J; Nery, FC; Netsch, C; Nguyen, TH; Ni, L; Ni, YX; Nie, W; Nielsen, LK; Nigam, K; Nikolayev, AA; Nishiyama, M; Niu, LL; Niu, PP; Nock, BA; Noer, PR; Noll, G; Noll, S; Norenberg, JP; Nowicka, J; Nutho, B; O'Connor, M; Obonyo, NG; Ochiai, T; Ochoa, MC; Oh, BL; Oh, S; Olczak, J; Olivares, X; Ommurugan, B; Oosthuizen, MC; Operario, D; Orešič, M; Oshima, K; Otano, I; Ou, Y; Owen, TW; Oxvig, C; Pacey, V; Pai, M; Paik, H; Paiva, R; Palmieri, EM; Palpant, N; Pan, L; Pan, Q; Panahi, S; Pang, B; Pang, ZC; Pannecouque, C; Paris, L; Park, D; Park, DJ; Park, E; Park, EC; Park, IH; Park, JH; Park, JI; Park, S; Passmore, MR; Pattaranggoon, NC; Paun, M; Pedersen, S; Pedron, J; Peng, M; Peng, X; Penzhorn, BL; Pérez-Camargo, D; Perez-Maldonado, R; Pérez-Vicente, C; Pham, TD; Pickering, L; Pickersgill, NA; Pinault, E; Pinotsis, N; Plan, M; Pocino, K; Poh, CL; Pons, EDC; Popoff, MR; Porri, D; Pourmand, A; Pratviel, G; Prudente, DO; Qi, H; Qi, N; Qian, LY; Qiao, L; Qiao, Q; Qin, QP; Qiu, N; Qiu, SW; Qu, F; Quan, M; Quigg, A; Raee, E; Raibaud, P; Ramanitrahasimbola, D; Rapoport, L; Rasby, RJ; Rasoanirina, BNV; Raspini, B; Ratner, JR; Razafindrakoto, Z; Redd, MA; Ren, H; Ren, N; Rey, J; Reynolds, CP; Rich, PR; Richards, CJ; Rigol, M; Rimoldi, S; Robert, P; Rodrigues, AE; Roe, JH; Rohde, S; Rokita, JL; Roland, J; Rombaut, L; Ronkainen, J; Rothenberg, SM; Roy, SC; Ruan, Z; Rucker, PV; Rueda, D; Ruhwald, M; Rungrotmongkol, T; Rupert, AS; Rusjan, P; Ryabov, AD; Rysä, J; Saad, NES; Sabioni, P; Sadow, PM; Sahai, N; Salem, HF; Salinas, B; Salonurmi, T; Samé Guerra, D; Sánchez, J; Sanchez-González, J; Sanmamed, MF; Sansores-Peraza, P; Santoro, JC; Santschi, PH; Saritas, T; Sarkisova, Y; Savolainen, MJ; Scherberich, JE; Schlom, DG; Schmelz, EM; Schmid, MC; Schneider, MP; Schumacher, S; Schwartz, JC; Schwartzer, JJ; Schwehr, K; Schweitzer, DH; Scott, ME; Sedky, NK; See Hoe, L; Sejian, V; Selvaraju, S; Sen, SK; Seo, G; Šerý, O; Settles, JA; Sfar, S; Shaffer, J; Shan, GL; Shang, Q; Shannahan, JH; Shao, B; Shao, H; Shao, J; Shao, ZH; Shasha, Y; Shaw, K; Sheeba, V; Shekar, K; Shen, G; Shen, H; Shen, XD; Shen, Y; Sherrell, PC; Shete, PB; Shi, AX; Shi, J; Shi, JH; Shi, S; Shi, X; Shigeta, Y; Shimbo, A; Shin, E; Sikka, N; Silhavy, TJ; Simanon, N; Simard, S; Simon, J; Simon, M; Simpson, SD; Simundic, AM; Since, M; Singh, B; Singhroy, DN; Sinisterra, OT; Smith, EH; Sobreira, TJP; Solanes, N; Somasundar, Y; Sommerer, C; Sonei, A; Song, B; Song, E; Song, J; Song, M; Song, Y; Soo Lee, M; Sorensen, MD; Sournia-Saquet, A; Spaepen, E; Spirk, D; Srivastava, S; Stancill, JS; Stanczak, PS; Starenki, D; Starr, F; Step, DL; Steubl, D; Stigliani, JL; Stráská, J; Sträter, N; Su, ZZ; Sudano, I; Suen, JY; Suh, HJ; Sui, ZY; Suico, JG; Suleiman, K; Sumon, K; Sun, HB; Sun, J; Sun, L; Sun, LL; Sun, M; Sun, Q; Sun, W; Sun, X; Sun, XF; Sun, Y; Sun, YB; Sun, YH; Sun, YN; Sun, Z; Sunada, K; Suzuki, S; Sylvan, JB; Takala, J; Talla, D; Tamir, Z; Tan, SJ; Tanda, S; Tang, H; Tang, J; Tang, LF; Tang, SJ; Tang, Y; Tao, FB; Tappel, R; Taratkin, M; Teijeira, Á; Tellew, JE; Thomas, AM; Thomas, SG; Thomson, SR; Tian, J; Tie, Y; Tirado, JL; Tolonen, A; Tosato, G; Tronnet, A; Tsai, S; Turtoi, A; Turtoi, E; Tvrdoňová, M; Tyagi, A; Tzou, DT; Uddin Ahmad, Z; Urias, E; Usawachintachit, M; Ustriyana, P; Utsumi, F; Vacca, M; Vaculovič, T; Vaidya, SS; Valentin, A; Valgepea, K; van den Berg, P; van den Bergh, JP; van der Heiden, K; van Gaalen, K; Van Gemert, W; van Haard, PMM; van Hest, JCM; Vecchiarelli, E; Večeřa, Z; Venkatesh, R; Verhaeghe, P; Verhagen, HJ; Vetter, JM; Vieira, D; Vilchez-Tschischke, JP; Villena-Gutierrez, R; Villoslada Terrones, V; Vital-Jacome, M; Voelkl, J; Vogel, K; Vogrin, S; Volke, D; von Bahr, V; Vysloužil, J; Wade, TL; Wagner-Gillespie, M; Walsh, SW; Wan, LJ; Wan, SP; Wang, AL; Wang, B; Wang, BY; Wang, C; Wang, D; Wang, F; Wang, H; Wang, HR; Wang, HY; Wang, J; Wang, JY; Wang, K; Wang, L; Wang, LF; Wang, P; Wang, Q; Wang, R; Wang, SF; Wang, SP; Wang, SR; Wang, T; Wang, W; Wang, WP; Wang, X; Wang, XJ; Wang, Y; 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22 review(s) available for glucagon and Disease Models, Animal
Article | Year |
---|---|
A bright future for glucagon and alpha cell biology.
Topics: Animals; Disease Models, Animal; Glucagon; Glucagon-Secreting Cells; Glucose; Humans; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Mice | 2024 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus | 2016 |
Glucose effectiveness: Lessons from studies on insulin-independent glucose clearance in mice.
Topics: Administration, Intravenous; Adult; Aged; Animals; Biological Transport; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose; Homeostasis; Humans; Incretins; Insulin; Insulin Resistance; Insulin Secretion; Male; Mice; Middle Aged | 2021 |
Insights into the Hexose Liver Metabolism-Glucose versus Fructose.
Topics: Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Disease Models, Animal; Fructose; Glucagon; Gluconeogenesis; Glucose; Humans; Insulin; Lipogenesis; Liver; Meta-Analysis as Topic; Sterol Regulatory Element Binding Protein 1; Triglycerides; X-Box Binding Protein 1 | 2017 |
Metabolic phenotyping guidelines: assessing glucose homeostasis in rodent models.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Fasting; Female; Glucagon; Glucose; Glucose Tolerance Test; Guidelines as Topic; Homeostasis; Humans; Insulin; Insulin Resistance; Male; Mice; Phenotype; Pregnancy; Pregnancy in Diabetics; Rats; Somatostatin | 2014 |
Contribution of the distal small intestine to metabolic improvement after bariatric/metabolic surgery: Lessons from ileal transposition surgery.
Topics: Animals; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Eating; Endotoxemia; Enteroendocrine Cells; Gastric Bypass; Gastrointestinal Microbiome; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Ileum; Insulin; Insulin Resistance; Insulin Secretion; Rats | 2016 |
Are vasopressors useful in toxin-induced cardiogenic shock?
Topics: Animals; Antidepressive Agents, Tricyclic; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Drug Overdose; Glucagon; Heart Rate; Hemodynamics; Humans; Observational Studies as Topic; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Shock, Cardiogenic; Vasoconstrictor Agents | 2017 |
The evolving place of incretin-based therapies in type 2 diabetes.
Topics: Adolescent; Adult; Animals; Child; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion | 2010 |
Glucagon in beta-blocker and calcium channel blocker overdoses: a systematic review.
Topics: Adrenergic beta-Antagonists; Animals; Calcium Channel Blockers; Cardiotonic Agents; Disease Models, Animal; Dogs; Drug Overdose; Glucagon; Humans; Rats | 2003 |
The incretin approach for diabetes treatment: modulation of islet hormone release by GLP-1 agonism.
Topics: Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Humans; Islets of Langerhans; Peptide Fragments; Protein Precursors | 2004 |
Biochemical abnormalities in the Chinese hamster (Cricetulus griseus) with spontaneous diabetes.
Topics: Animals; Calcium; Cricetinae; Cricetulus; Cyclic AMP; Diabetes Mellitus; Disease Models, Animal; Glucagon; Gluconeogenesis; Glucose; Insulin; Islets of Langerhans; Kidney; Liver; Pancreas | 1981 |
Adipose tissue metabolism and its control in birds.
Topics: Adipose Tissue; Animal Feed; Animals; Birds; Chickens; Disease Models, Animal; Female; Glucagon; Gonadal Steroid Hormones; Insulin; Lipids; Lipolysis; Liver; Male; Obesity; Poultry; Poultry Diseases; Sex Factors; Triglycerides | 1984 |
Role of amylin in nutrient intake - animal studies.
Topics: Amyloid; Animal Nutritional Physiological Phenomena; Animals; Diabetes Mellitus; Disease Models, Animal; Eating; Gastric Emptying; Glucagon; Humans; Hypoglycemic Agents; Islet Amyloid Polypeptide; Receptors, Islet Amyloid Polypeptide; Receptors, Peptide | 1997 |
[ob/ob mouse].
Topics: Animals; Body Temperature Regulation; Disease Models, Animal; Glucagon; Insulin; Leptin; Mice; Mice, Obese; Obesity; Proteins | 1998 |
Glucagon and diabetes.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Glucagon; Humans; Molecular Weight; Streptozocin | 1977 |
The effects of hypoxaemia in fetal sheep.
Topics: Adrenocorticotropic Hormone; Animals; Blood Pressure; Chronic Disease; Disease Models, Animal; Epinephrine; Fatty Acids, Nonesterified; Female; Fetal Heart; Fetal Hypoxia; Glucagon; Glycogen; Heart Rate; Lactates; Norepinephrine; Pregnancy; Propranolol; Regional Blood Flow; Sheep; Vasopressins | 1977 |
The artificial pancreas.
Topics: Animals; Artificial Organs; Autoanalysis; Blood Glucose; Computers; Diabetes Mellitus; Disease Models, Animal; Dogs; Glucagon; Glucose; Glucose Tolerance Test; Homeostasis; Humans; Islets of Langerhans; Methods; Pancreas; Physical Exertion; Time Factors | 1977 |
Peptidergic regulation of feeding.
Topics: Afferent Pathways; Animals; Bombesin; Brain Mapping; Calcitonin; Calcitonin Gene-Related Peptide; Cholecystokinin; Corticotropin-Releasing Hormone; Disease Models, Animal; Endorphins; Feeding Behavior; Glucagon; Humans; Insulin; Motilin; Nerve Tissue Proteins; Neuropeptide Y; Neurotensin; Obesity; Pancreatic Polypeptide; Satiety Response; Somatostatin; Species Specificity; Stress, Psychological; Taste; Thyrotropin-Releasing Hormone | 1985 |
Neonatal sepsis: metabolic and hormonal considerations.
Topics: Animals; Animals, Newborn; Blood Glucose; Disease Models, Animal; Glucagon; Gluconeogenesis; Glycogen; Homeostasis; Humans; Infant, Newborn; Insulin; Liver; Sepsis | 1988 |
Is there an animal model for gestational diabetes?
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Gestational Age; Glucagon; Glucose; Hydrocortisone; Insulin; Insulin Resistance; Islets of Langerhans; Mice; Pregnancy; Pregnancy in Diabetics; Progesterone; Rats | 1985 |
Pathophysiology and therapy of the shock of myocardial infarction.
Topics: Acute Disease; Animals; Coronary Vessels; Digitalis Glycosides; Dilatation; Disease Models, Animal; Dopamine; Glucagon; Hemodynamics; Humans; Isoproterenol; Myocardial Infarction; Myocardium; Oxygen Consumption; Regional Blood Flow; Shock, Cardiogenic; Sympathomimetics; Vasodilator Agents | 1970 |
Adaptation following intestinal resection: mechanisms and signals.
Topics: Animals; Biomarkers; Disease Models, Animal; Epidermal Growth Factor; Glucagon-Like Peptides; Glucocorticoids; Glutamine; Growth Hormone; Humans; Insulin-Like Growth Factor I; Intestinal Absorption; Intestinal Mucosa; Intestines; Peptides; Short Bowel Syndrome | 2003 |
2 trial(s) available for glucagon and Disease Models, Animal
Article | Year |
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Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus | 2016 |
Effects of dexmedetomidine and MK-467 on plasma glucose, insulin and glucagon in a glibenclamide-induced canine hypoglycaemia model.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia, Intravenous; Animals; Blood Glucose; Cross-Over Studies; Dexmedetomidine; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glucagon; Glyburide; Hypnotics and Sedatives; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Quinolizines; Random Allocation; Treatment Outcome | 2018 |
303 other study(ies) available for glucagon and Disease Models, Animal
Article | Year |
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Phosphoproteomics analysis of diabetic cardiomyopathy in aging-accelerated mice and effects of D-pinitol.
Topics: Aging; Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Disease Models, Animal; Glucagon; Heart; Inositol; Insulin; Mice; Myocardium; Phosphopeptides; Phosphorylation; Protein Interaction Maps; Proteomics; Signal Transduction | 2022 |
Low-Order Nonlinear Animal Model of Glucose Dynamics for a Bihormonal Intraperitoneal Artificial Pancreas.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 1; Disease Models, Animal; Glucagon; Glucose; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Pancreas, Artificial; Swine | 2022 |
Effects of ALT-801, a GLP-1 and glucagon receptor dual agonist, in a translational mouse model of non-alcoholic steatohepatitis.
Topics: Animals; Cholesterol; Collagen; Disease Models, Animal; Galectin 3; Glucagon; Glucagon-Like Peptide 1; Inflammation; Interleukin-2; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Non-alcoholic Fatty Liver Disease; Obesity; Receptors, Antigen, T-Cell; Receptors, Glucagon; Recombinant Fusion Proteins; Transaminases; Triglycerides | 2022 |
Glucagon-receptor-antagonism-mediated β-cell regeneration as an effective anti-diabetic therapy.
Topics: Animals; Diabetes Mellitus, Type 1; Disease Models, Animal; Glucagon; Glucagon-Secreting Cells; Hyperglycemia; Insulin-Secreting Cells; Mice; Receptors, Glucagon | 2022 |
Disrupted and Elevated Circadian Secretion of Glucagon-Like Peptide-1 in a Murine Model of Type 2 Diabetes.
Topics: Animals; Circadian Rhythm; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Humans; Insulin; Mice | 2022 |
Preclinical exploration of combined glucagon inhibition and liver-preferential insulin for treatment of diabetes using in vitro assays and rat and mouse models.
Topics: Alanine Transaminase; Animals; Blood Glucose; Diabetes Mellitus; Disease Models, Animal; Glucagon; Hyperglycemia; Hypoglycemia; Insulin; Liver; Mice; Rats; Receptors, Glucagon; Streptozocin | 2023 |
The Effects of Dual GLP-1/Glucagon Receptor Agonists with Different Receptor Selectivity in Mouse Models of Obesity and Nonalcoholic Steatohepatitis.
Topics: Animals; Body Weight; Complement C4; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Lipids; Mice; Non-alcoholic Fatty Liver Disease; Obesity; Receptors, Glucagon | 2023 |
Effects of Moderate Chronic Food Restriction on the Development of Postprandial Dyslipidemia with Ageing.
Topics: Adiposity; Aging; Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Blood Glucose; Diet, Fat-Restricted; Dietary Fats; Disease Models, Animal; Dyslipidemias; Glucagon; Insulin; Lipids; Liver; Metabolic Syndrome; Postprandial Period; Rats; Rats, Wistar; Triglycerides | 2019 |
Inactivation of NF-κB2 (p52) restrains hepatic glucagon response via preserving PDE4B induction.
Topics: Animals; Blood Glucose; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Diet, High-Fat; Disease Models, Animal; Fasting; Gene Expression Regulation; Gene Knockdown Techniques; Ginsenosides; Glucagon; Gluconeogenesis; Glucose; Hep G2 Cells; Humans; Liver; Male; Metabolic Diseases; Metformin; Mice; Mice, Inbred C57BL; NF-kappa B p52 Subunit; Promoter Regions, Genetic; Signal Transduction | 2019 |
Topics: Amidohydrolases; Amino Acid Substitution; Animals; Blood Glucose; Disease Models, Animal; Eating; Ethanolamines; Female; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Humans; Injections, Intravenous; Insulin; Islets of Langerhans; Male; Metabolic Syndrome; Mice; Mice, Transgenic; Middle Aged; Oleic Acids; Postprandial Period; Receptors, G-Protein-Coupled; Taurine | 2019 |
UCP1-independent glucose-lowering effect of leptin in type 1 diabetes: only in conditions of hypoleptinemia.
Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Blood Glucose; Corticosterone; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Eating; Glucagon; Gluconeogenesis; Humans; Insulin; Insulin-Like Growth Factor I; Leptin; Mice; Mice, Knockout; Oxygen Consumption; Peptides; Pyruvic Acid; Receptor, Insulin; Transcriptome; Uncoupling Protein 1 | 2020 |
Hepatic TET3 contributes to type-2 diabetes by inducing the HNF4α fetal isoform.
Topics: Animals; Diabetes Mellitus, Type 2; Dioxygenases; Disease Models, Animal; DNA Demethylation; DNA Methylation; DNA-Binding Proteins; Fasting; Gene Expression Regulation; Glucagon; Glucose; Hepatocyte Nuclear Factor 3-beta; Hepatocyte Nuclear Factor 4; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Promoter Regions, Genetic; Protein Isoforms; Transcriptional Activation; Transcriptome; Up-Regulation | 2020 |
Molecular changes in hepatic metabolism in ZDSD rats-A new polygenic rodent model of obesity, metabolic syndrome, and diabetes.
Topics: Amino Acids; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Humans; Hypertension; Insulin; Lipid Metabolism; Liver; Male; Metabolic Syndrome; Multifactorial Inheritance; Obesity; Pancreas; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Rats, Zucker | 2020 |
Consuming a ketogenic diet leads to altered hypoglycemic counter-regulation in mice.
Topics: Animals; Blood Glucose; Cerebrum; Corticosterone; Diet, Ketogenic; Disease Models, Animal; Feedback, Physiological; Glucagon; Glucose; Hypoglycemia; Male; Mice; Mice, Inbred C57BL; Risk Factors | 2020 |
Modulatory role of imatinib mesylate on pancreatic β-cells' secretory functions in an STZ rat model of diabetes mellitus.
Topics: Administration, Oral; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antioxidants; Biomarkers; Blood Glucose; Body Weight; Caspase 3; Catalase; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Glutathione; Imatinib Mesylate; Insulin; Insulin-Secreting Cells; Male; Malondialdehyde; Organ Size; Oxidation-Reduction; Oxidative Stress; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase | 2020 |
Dapagliflozin promotes beta cell regeneration by inducing pancreatic endocrine cell phenotype conversion in type 2 diabetic mice.
Topics: Animals; Benzhydryl Compounds; Blood Glucose; C-Peptide; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Endocrine Cells; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Secreting Cells; Glucose; Glucosides; Insulin; Insulin-Secreting Cells; Male; Mice; Proprotein Convertase 1; Regeneration; Sodium-Glucose Transporter 2 Inhibitors | 2020 |
The GPR40 Full Agonist SCO-267 Improves Liver Parameters in a Mouse Model of Nonalcoholic Fatty Liver Disease without Affecting Glucose or Body Weight.
Topics: Administration, Oral; Animals; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucose; Liver; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Receptors, G-Protein-Coupled; Triglycerides | 2020 |
An Inducible Diabetes Mellitus Murine Model Based on MafB Conditional Knockout under MafA-Deficient Condition.
Topics: Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Disease Models, Animal; Gene Expression Regulation; Glucagon; Glucose Tolerance Test; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Maf Transcription Factors, Large; MafB Transcription Factor; Mice, Knockout | 2020 |
Deficiency of glucagon gene-derived peptides induces peripheral polyneuropathy in mice.
Topics: Animals; Diabetic Neuropathies; Disease Models, Animal; Ganglia, Spinal; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Fibers, Myelinated; Neural Conduction; Neuronal Outgrowth; Receptors, Glucagon; RNA, Messenger | 2020 |
The mediation by GLP-1 receptors of glucagon-induced insulin secretion revisited in GLP-1 receptor knockout mice.
Topics: Animals; Blood Glucose; Disease Models, Animal; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucose; Histone-Lysine N-Methyltransferase; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mice; Mice, Knockout; Pancreas; Peptide Fragments | 2021 |
Glucagon Resistance and Decreased Susceptibility to Diabetes in a Model of Chronic Hyperglucagonemia.
Topics: Animals; Blood Glucose; Body Weight; Disease Models, Animal; Disease Susceptibility; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Glucose Intolerance; Insulin; Insulin Secretion; Mechanistic Target of Rapamycin Complex 1; Mice; Receptors, Glucagon; Signal Transduction; Tuberous Sclerosis Complex 2 Protein | 2021 |
Optogenetic stimulation of the liver-projecting melanocortinergic pathway promotes hepatic glucose production.
Topics: Acetylcholine; Action Potentials; Animals; Arcuate Nucleus of Hypothalamus; Blood Glucose; Cholinergic Neurons; Corticosterone; Disease Models, Animal; Efferent Pathways; Female; Gene Knockdown Techniques; Glucagon; Gluconeogenesis; Humans; Hypoglycemia; Insulin; Liver; Male; Mice; Optogenetics; Pro-Opiomelanocortin; Receptor, Melanocortin, Type 4; RNA, Messenger; Up-Regulation; Vagus Nerve | 2020 |
S3-2, a novel long-lasting oxyntomodulin derivative, exerts improvement on diabesity and renal injury through activating GLP-1 and glucagon receptors.
Topics: Albumins; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose; Hypoglycemic Agents; Insulin; Kidney; Male; Mice; Mice, Inbred C57BL; Obesity; Oxyntomodulin; Peptides; Receptors, Glucagon | 2021 |
Optogenetic stimulation of cholinergic fibers for the modulation of insulin and glycemia.
Topics: Animals; Axons; Blood Glucose; Channelrhodopsins; Choline O-Acetyltransferase; Cholinergic Fibers; Cholinergic Neurons; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Optogenetics; Pancreas; Vagus Nerve; Vagus Nerve Stimulation | 2021 |
Role of insulin/glucagon ratio and cell redox state in the hyperglycaemia induced by exposure to a 60-Hz magnetic field in rats.
Topics: Animals; Biomarkers; Disease Models, Animal; Disease Susceptibility; Electromagnetic Fields; Energy Metabolism; Fasting; Glucagon; Hyperglycemia; Insulin; Lactic Acid; Lipids; Metabolomics; Oxidation-Reduction; Pyruvic Acid; Rats | 2021 |
Grape-Seed Proanthocyanidin Extract Reverts Obesity-Related Metabolic Derangements in Aged Female Rats.
Topics: Adiposity; Animals; Blood Glucose; Disease Models, Animal; Fatty Liver; Female; Glucagon; Grape Seed Extract; Insulin; Obesity; Proanthocyanidins; Rats; Rats, Wistar; Weight Loss | 2021 |
Slow but Steady-The Responsiveness of Sympathoadrenal System to a Hypoglycemic Challenge in Ketogenic Diet-Fed Rats.
Topics: 3-Hydroxybutyric Acid; Adrenal Glands; Animals; Blood Glucose; Diet, Ketogenic; Disease Models, Animal; Epinephrine; Glucagon; Glucose; Hypoglycemia; Hypoglycemic Agents; Insulin; Ketosis; Male; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Sympathoadrenal System | 2021 |
Curcumin reverses the depressive-like behavior and insulin resistance induced by chronic mild stress.
Topics: Animals; Behavior, Animal; Blood Glucose; Corticosterone; Curcumin; Depression; Disease Models, Animal; Glucagon; Glucose Tolerance Test; Insulin; Insulin Resistance; Leptin; Male; Pioglitazone; Rats; Rats, Sprague-Dawley; Stress, Psychological; Thiazolidinediones | 2017 |
Central and Peripheral Glucagon Reduces Hyperlipidemia in Rats and Hamsters.
Topics: Acyl Coenzyme A; Animals; Cholesterol; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Glucagon; Hyperlipidemias; Injections, Intraventricular; Injections, Subcutaneous; Lipid Metabolism; Lipids; Liver; Male; Mesocricetus; Rats; Rats, Sprague-Dawley; Triglycerides | 2017 |
Role of Glucagon in Catabolism and Muscle Wasting of Critical Illness and Modulation by Nutrition.
Topics: Aged; Amino Acids; Animals; Blood Glucose; Critical Illness; Disease Models, Animal; Female; Glucagon; Glucose; Humans; Insulin; Male; Mice; Middle Aged; Muscular Atrophy; Parenteral Nutrition; Treatment Outcome | 2017 |
Beneficial effect of combined treatment with octreotide and pasireotide in PCK rats, an orthologous model of human autosomal recessive polycystic kidney disease.
Topics: Animals; Blood Glucose; Body Weight; Cyclic AMP; Disease Models, Animal; Drug Interactions; Extracellular Signal-Regulated MAP Kinases; Glucagon; Heart; Humans; Hydrocortisone; Hyperglycemia; Insulin; Insulin-Like Growth Factor I; Ki-67 Antigen; Kidney; Liver; Male; Octreotide; Phosphoproteins; Polycystic Kidney, Autosomal Recessive; Rats; Receptor, IGF Type 1; Ribosomal Protein S6 Kinases; Somatostatin | 2017 |
Acute bout of exercise induced prolonged muscle glucose transporter-4 translocation and delayed counter-regulatory hormone response in type 1 diabetes.
Topics: Animals; Blood Glucose; Catecholamines; Diabetes Mellitus, Type 1; Disease Models, Animal; Glucagon; Glucose Transporter Type 4; Glucose-6-Phosphate; Insulin; Male; Physical Conditioning, Animal; Protein Transport; Rats; Rats, Wistar; Signal Transduction | 2017 |
Recycling of glucagon receptor to plasma membrane increases in adipocytes of obese rats by soy protein; implications for glucagon resistance.
Topics: Adipocytes; Adipose Tissue, White; Animals; Cell Membrane; Diabetes Mellitus, Type 2; Diet; Disease Models, Animal; Gene Expression Regulation; Glucagon; Hyperglycemia; Male; Obesity; rab GTP-Binding Proteins; Rats; Rats, Zucker; Receptors, Glucagon; Soybean Proteins; Triglycerides | 2017 |
Degradation of PHLPP2 by KCTD17, via a Glucagon-Dependent Pathway, Promotes Hepatic Steatosis.
Topics: Adaptor Proteins, Signal Transducing; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Genetic Predisposition to Disease; Glucagon; Hep G2 Cells; Humans; Lipogenesis; Liver; Liver Neoplasms; Male; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Obesity; Phenotype; Phosphoprotein Phosphatases; Phosphorylation; Proteolysis; Signal Transduction | 2017 |
Balanced Coagonist of GLP-1 and Glucagon Receptors Corrects Dyslipidemia by Improving FGF21 Sensitivity in Hamster Model.
Topics: Adipose Tissue; Aminoisobutyric Acids; Animals; Bile; Cholesterol; Cricetinae; Diet, High-Fat; Dipeptides; Disease Models, Animal; Fibroblast Growth Factors; Glucagon; Glucagon-Like Peptide 1; Homeostasis; Hyperlipidemias; Lipolysis; Liver; Male; Peptide Fragments; Polyethylene Glycols; Receptors, Fibroblast Growth Factor; Receptors, Glucagon; Triglycerides | 2017 |
Simultaneous K-ras activation and Keap1 deletion cause atrophy of pancreatic parenchyma.
Topics: Animals; Atrophy; Blood Glucose; Disease Models, Animal; Female; Gene Deletion; Genes, p53; Genes, ras; Genetic Predisposition to Disease; Glucagon; Homeodomain Proteins; Insulin; Integrases; Kelch-Like ECH-Associated Protein 1; Male; Mice, Knockout; Mutation; NF-E2-Related Factor 2; Pancreas; Pancreatitis, Chronic; Parenchymal Tissue; Phenotype; Trans-Activators | 2018 |
Neuroprotective effects of a triple GLP-1/GIP/glucagon receptor agonist in the APP/PS1 transgenic mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Hippocampus; Memory Disorders; Mice; Mice, Transgenic; Neuroprotective Agents; Plaque, Amyloid; Presenilin-1; Receptors, Gastrointestinal Hormone; Receptors, Glucagon | 2018 |
Characterization of somatostatin receptors and associated signaling pathways in pancreas of R6/2 transgenic mice.
Topics: Animals; Diabetes Mellitus; Disease Models, Animal; Gene Expression Regulation; Glucagon; Glutamate Decarboxylase; Huntington Disease; Insulin; Islets of Langerhans; Male; Mice; Mice, Transgenic; Microscopy, Confocal; Pancreas; Receptors, Somatostatin; RNA, Messenger; Signal Transduction; Somatostatin; Synaptophysin; Tyrosine 3-Monooxygenase | 2018 |
Evaluation of the insulinotropic and glucose-lowering actions of zebrafish GIP in mammalian systems: Evidence for involvement of the GLP-1 receptor.
Topics: Animals; Blood Glucose; Disease Models, Animal; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucose; Glucose Tolerance Test; HEK293 Cells; Humans; Insulin; Insulin-Secreting Cells; Mice; Rats; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Zebrafish | 2018 |
Additional dexamethasone in chemotherapies with carboplatin and paclitaxel could reduce the impaired glycometabolism in rat models.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Glucose; Carboplatin; Dexamethasone; Disease Models, Animal; Female; Glucagon; Humans; Hyperglycemia; Insulin; Ovarian Neoplasms; Paclitaxel; Rats | 2018 |
Long-lasting Glucagon-like Peptide 1 Analogue Exendin-4 Ameliorates the Secretory and Synthetic Function of Islets Isolated From Severely Scalded Rats.
Topics: Animals; Blood Glucose; Burns; Disease Models, Animal; Exenatide; Glucagon; Insulin; Islets of Langerhans; Male; Rats; Rats, Wistar; RNA, Messenger | 2018 |
A long-acting FGF21 alleviates hepatic steatosis and inflammation in a mouse model of non-alcoholic steatohepatitis partly through an FGF21-adiponectin-IL17A pathway.
Topics: Adiponectin; Animals; Anti-Inflammatory Agents; Blood Glucose; Body Weight; Delayed-Action Preparations; Disease Models, Animal; Fibroblast Growth Factors; Glucagon; Insulin; Interleukin-17; Lipids; Liver; Male; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Signal Transduction | 2018 |
Nutritional recovery with a soybean diet impaired the glucagon response but did not alter liver gluconeogenesis in the adult offspring of rats deprived of protein during pregnancy and lactation.
Topics: Age Factors; Animal Feed; Animals; Diet, Protein-Restricted; Disease Models, Animal; Female; Gene Expression Regulation, Enzymologic; Glucagon; Gluconeogenesis; Glycine max; Lactation; Liver; Male; Nutritional Status; Pregnancy; Prenatal Exposure Delayed Effects; Prenatal Nutritional Physiological Phenomena; Protein-Energy Malnutrition; Rats, Wistar | 2019 |
Gastric Plication and Sleeve Gastrectomy in an Experimental Model of Obesity: New Insights into Weight Loss, Intake and Metabolic Results.
Topics: Animals; Blood Glucose; Diet, High-Fat; Disease Models, Animal; Energy Intake; Gastrectomy; Ghrelin; Glucagon; Laparoscopy; Male; Obesity; Random Allocation; Rats; Rats, Sprague-Dawley; Stomach; Weight Loss | 2018 |
Preventive treatment with liraglutide protects against development of glucose intolerance in a rat model of Wolfram syndrome.
Topics: Animals; Blood Glucose; Calmodulin-Binding Proteins; Disease Models, Animal; Endoplasmic Reticulum Stress; Gene Knockout Techniques; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucose Intolerance; Glucose Tolerance Test; Humans; Incretins; Injections, Subcutaneous; Insulin; Islets of Langerhans; Liraglutide; Male; Membrane Proteins; Rats; Rats, Transgenic; Treatment Outcome; Wolfram Syndrome | 2018 |
Molecular reductions in glucokinase activity increase counter-regulatory responses to hypoglycemia in mice and humans with diabetes.
Topics: Adult; Animals; Blood Glucose; Diabetes Mellitus; Disease Models, Animal; Epinephrine; Female; Glucagon; Glucokinase; Glucose; Glucose Clamp Technique; Humans; Hyperinsulinism; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Male; Mice; Mice, Inbred BALB C; Middle Aged | 2018 |
Deletion of the glucagon receptor gene before and after experimental diabetes reveals differential protection from hyperglycemia.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide-1 Receptor; Hyperglycemia; Insulin; Insulin-Secreting Cells; Male; Mice; Mice, Knockout; Receptors, Glucagon; Streptozocin; Transcriptome | 2018 |
Glucose intolerance in monosodium glutamate obesity is linked to hyperglucagonemia and insulin resistance in α cells.
Topics: Adipose Tissue, White; Animals; Biomarkers; Blood Glucose; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Glucagon; Glucagon-Secreting Cells; Glucose Intolerance; Insulin; Insulin Resistance; Liver; Male; Mice; Obesity; Phosphoenolpyruvate Carboxykinase (ATP); Phosphorylation; Sodium Glutamate; TOR Serine-Threonine Kinases | 2019 |
SGLT1 in pancreatic α cells regulates glucagon secretion in mice, possibly explaining the distinct effects of SGLT2 inhibitors on plasma glucagon levels.
Topics: Animals; Benzhydryl Compounds; Blood Glucose; Canagliflozin; Diabetes Mellitus; Diet, High-Fat; Disease Models, Animal; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Glucose; Glucosides; Glycosuria; Hypoglycemic Agents; Insulin; Male; Mice; Mice, Inbred C57BL; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2019 |
Acute pancreatic beta cell apoptosis by IL-1β is responsible for postburn hyperglycemia: Evidence from humans and mice.
Topics: Acute Disease; Adult; Animals; Apoptosis; Blood Glucose; Burns; Disease Models, Animal; Female; Glucagon; Glucocorticoids; Humans; Hyperglycemia; Insulin; Insulin Secretion; Insulin-Secreting Cells; Interleukin-1beta; Male; Mice, Inbred C57BL; Models, Biological; Neutralization Tests; Survival Analysis | 2019 |
Topics: Animals; Atherosclerosis; Cells, Cultured; Cytoprotection; Diet, High-Fat; Disease Models, Animal; Glucagon; Humans; Kupffer Cells; Lipid Metabolism; Liver; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Microarray Analysis; Phenotype; Schistosoma mansoni; Schistosomiasis mansoni; Signal Transduction; Transcriptional Activation | 2018 |
Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells.
Topics: Animals; Biomarkers; Cell Lineage; Cellular Reprogramming; Diabetes Mellitus; Disease Models, Animal; Female; Glucagon; Glucagon-Secreting Cells; Glucose; Homeodomain Proteins; Humans; Insulin; Islets of Langerhans; Maf Transcription Factors, Large; Male; Mice; Organ Specificity; Pancreatic Polypeptide; Pancreatic Polypeptide-Secreting Cells; Proteomics; Sequence Analysis, RNA; Trans-Activators; Transcriptome; Transduction, Genetic | 2019 |
26S Proteasomes are rapidly activated by diverse hormones and physiological states that raise cAMP and cause Rpn6 phosphorylation.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Epinephrine; Glucagon; Hepatocytes; Humans; Kidney; Male; Mice; Muscle, Skeletal; Phosphorylation; Proteasome Endopeptidase Complex; Proteolysis; Proteostasis Deficiencies; Rats; Rats, Sprague-Dawley; Rats, Wistar; Ubiquitinated Proteins | 2019 |
Intra-islet glucagon signaling is critical for maintaining glucose homeostasis.
Topics: Animals; Blood Glucose; Disease Models, Animal; Female; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucagon-Secreting Cells; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Male; Mice; Mice, Transgenic; Paracrine Communication; Receptors, G-Protein-Coupled; Signal Transduction | 2019 |
Pancreatic alpha-cell mass in the early-onset and advanced stage of a mouse model of experimental autoimmune diabetes.
Topics: Animals; B7-1 Antigen; Cell Proliferation; Cell Transdifferentiation; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Glucagon-Secreting Cells; Homeodomain Proteins; Hyperglycemia; Insulin; Mice; Mice, Inbred C57BL; Mice, Transgenic; Trans-Activators | 2019 |
Glucagon lowers glycemia when β-cells are active.
Topics: Animals; Blood Glucose; Disease Models, Animal; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucose; Homeostasis; Hypoglycemia; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Postprandial Period | 2019 |
Nilotinib enhances β-islets integrity and secretory functions in a rat model of STZ-induced diabetes mellitus.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Apoptosis; Blood Glucose; Body Weight; Caspase 3; Catalase; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glucagon; Glutathione; Insulin; Insulin-Secreting Cells; Male; Malondialdehyde; Organ Size; Oxidative Stress; Pyrimidines; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2019 |
Rosiglitazone treatment of type 2 diabetic db/db mice attenuates urinary albumin and angiotensin converting enzyme 2 excretion.
Topics: ADAM Proteins; ADAM17 Protein; Albuminuria; Angiotensin-Converting Enzyme 2; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Glucose Tolerance Test; Glycosuria; Hyperglycemia; Hypoglycemic Agents; Kidney Diseases; Male; Membrane Proteins; Mice; Peptidyl-Dipeptidase A; Rosiglitazone; Thiazolidinediones; Tissue Inhibitor of Metalloproteinase-3; Triglycerides | 2013 |
Effect of combined therapy of human Wharton's jelly-derived mesenchymal stem cells from umbilical cord with sitagliptin in type 2 diabetic rats.
Topics: Animals; C-Peptide; Cell Proliferation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Glycated Hemoglobin; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Pyrazines; Rats; Rats, Wistar; Sitagliptin Phosphate; Streptozocin; Treatment Outcome; Triazoles; Umbilical Cord | 2014 |
A mixed mirror-image DNA/RNA aptamer inhibits glucagon and acutely improves glucose tolerance in models of type 1 and type 2 diabetes.
Topics: Animals; Aptamers, Nucleotide; Blood Glucose; Body Weight; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Fasting; Glucagon; Glucose Tolerance Test; Humans; Kinetics; Male; Mice; Mice, Inbred BALB C; RNA | 2013 |
Increasing glucagon secretion could antagonize the action of exogenous insulin for glycemic control in streptozocin-induced diabetic rhesus monkeys.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Glucagon; Glucagon-Secreting Cells; Hypoglycemic Agents; Insulin; Insulin Resistance; Longitudinal Studies; Macaca mulatta; Streptozocin; Time Factors; Treatment Outcome; Triglycerides | 2013 |
TAK-875, a GPR40/FFAR1 agonist, in combination with metformin prevents progression of diabetes and β-cell dysfunction in Zucker diabetic fatty rats.
Topics: Animals; Benzofurans; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Glucagon; Glycated Hemoglobin; Homeodomain Proteins; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Metformin; Proliferating Cell Nuclear Antigen; Rats; Rats, Zucker; Receptors, G-Protein-Coupled; Sulfones; Time Factors; Trans-Activators | 2013 |
Metabolic disturbances and defects in insulin secretion in rats with streptozotocin-nicotinamide-induced diabetes.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Glucose; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Niacinamide; Rats; Rats, Wistar; Severity of Illness Index; Streptozocin | 2013 |
Resveratrol prevents β-cell dedifferentiation in nonhuman primates given a high-fat/high-sugar diet.
Topics: Animals; Blood Glucose; Body Weight; Cell Dedifferentiation; Densitometry; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Dietary Sucrose; Disease Models, Animal; Fluorescent Antibody Technique; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Glucose Tolerance Test; Glycated Hemoglobin; Homeobox Protein Nkx-2.2; Homeodomain Proteins; Insulin; Insulin Resistance; Insulin-Secreting Cells; Islets of Langerhans; Macaca mulatta; Nuclear Proteins; Protective Agents; Resveratrol; Sirtuin 1; Stilbenes; Transcription Factors | 2013 |
The inactivation of Arx in pancreatic α-cells triggers their neogenesis and conversion into functional β-like cells.
Topics: Animals; Cell Differentiation; Diabetes Mellitus, Type 1; Disease Models, Animal; Gene Expression Regulation; Glucagon; Glucagon-Secreting Cells; Homeodomain Proteins; Humans; Insulin-Secreting Cells; Islets of Langerhans; Mice, Transgenic; Paired Box Transcription Factors; Transcription Factors | 2013 |
IL-2 immunotherapy reveals potential for innate beta cell regeneration in the non-obese diabetic mouse model of autoimmune diabetes.
Topics: Animals; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Glucagon; Immunotherapy; Insulin; Insulin-Secreting Cells; Interleukin-2; Mice; Mice, Inbred NOD; Regeneration; T-Lymphocytes, Regulatory | 2013 |
Addition of glucagon to adrenaline improves hemodynamics in a porcine model of prolonged ventricular fibrillation.
Topics: Animals; Blood Pressure; Cardiopulmonary Resuscitation; Disease Models, Animal; Drug Therapy, Combination; Epinephrine; Glucagon; Heart Arrest; Heart Rate; Hemodynamics; Male; Swine; Ventricular Fibrillation | 2014 |
Effect of sitagliptin treatment on metabolism and cardiac function in genetic diabetic mice.
Topics: Adiponectin; Animals; Blood Glucose; Body Weight; Diabetes Mellitus; Diet, High-Fat; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 1; Glycated Hemoglobin; Heart; Heart Function Tests; Hypoglycemic Agents; Insulin; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Myocardium; Pyrazines; Sitagliptin Phosphate; Triazoles | 2014 |
Islets of Langerhans from prohormone convertase-2 knockout mice show α-cell hyperplasia and tumorigenesis with elevated α-cell neogenesis.
Topics: Adenoma; Animals; Carcinogenesis; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Epithelial-Mesenchymal Transition; Female; Glucagon; Glucagon-Secreting Cells; Hyperplasia; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pancreatic Neoplasms; Proprotein Convertase 2 | 2014 |
Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones.
Topics: Animals; Binding Sites; Blood Glucose; Catalytic Domain; Diabetes Mellitus, Type 2; Disease Models, Animal; Gastric Emptying; Genetic Predisposition to Disease; Glucagon; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Insulysin; Islet Amyloid Polypeptide; Macrocyclic Compounds; Male; Mice; Mice, Inbred C57BL; Models, Molecular; Obesity; Signal Transduction; Thinness | 2014 |
Novel antidiabetic nutrients identified by in vivo screening for gastric secretion and emptying regulation in rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Food; Gastric Emptying; Glucagon; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Postprandial Period; Rats, Wistar | 2014 |
Hyperglycemia in rodent models of type 2 diabetes requires insulin-resistant alpha cells.
Topics: Animals; Blood Glucose; Body Temperature; Body Weight; Cell Line; Ceramides; Cricetinae; Diabetes Mellitus, Type 2; Diet; Disease Models, Animal; Feeding Behavior; Glucagon; Glucagon-Secreting Cells; Hyperglycemia; Hyperinsulinism; Insulin; Insulin-Secreting Cells; Lipogenesis; Male; Mice, Inbred C57BL; Rats; Receptors, Glucagon; RNA, Messenger | 2014 |
Glucagon-induced angiogenesis and tumor growth through the HIF-1-VEGF-dependent pathway in hyperglycemic nude mice.
Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Glucagon; Heterografts; Humans; Hyperglycemia; Hypoxia-Inducible Factor 1; Mice; Mice, Nude; Mice, Obese; Neoplasms; Neovascularization, Pathologic; Signal Transduction; Tumor Burden; Tumor Microenvironment; Vascular Endothelial Growth Factor A | 2014 |
Evaluation of CART-, glucagon-, and insulin-immunoreactive cells in the pancreas of an experimental rat model of unilateral renal artery stenosis.
Topics: Animals; Disease Models, Animal; Glucagon; Hypertension, Renovascular; Immunohistochemistry; Insulin; Male; Nerve Tissue Proteins; Pancreas; Rats; Rats, Wistar; Renal Artery Obstruction | 2015 |
Maternal insulin resistance and transient hyperglycemia impact the metabolic and endocrine phenotypes of offspring.
Topics: Animals; Animals, Newborn; Blood Glucose; Cell Proliferation; Diabetes, Gestational; Disease Models, Animal; Female; Glucagon; Glucagon-Like Peptide 1; Hyperglycemia; Hyperinsulinism; Insulin; Insulin Resistance; Insulin-Secreting Cells; Islets of Langerhans; Leptin; Mice; Organ Size; Phenotype; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Weight Gain | 2014 |
Selective disruption of Tcf7l2 in the pancreatic β cell impairs secretory function and lowers β cell mass.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Gene Deletion; Genetic Loci; Genome-Wide Association Study; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Insulin; Insulin Secretion; Insulin-Secreting Cells; Integrases; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Weight; Pancreas; Polymorphism, Single Nucleotide; Receptors, Glucagon; Transcription Factor 7-Like 2 Protein; Wnt Signaling Pathway | 2015 |
Vitamin A deficiency causes hyperglycemia and loss of pancreatic β-cell mass.
Topics: Animals; Apoptosis; Cell Proliferation; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Hyperglycemia; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Retinoic Acid 4-Hydroxylase; Retinoids; Retinol-Binding Proteins, Cellular; Signal Transduction; Vitamin A Deficiency | 2015 |
Protective effects of pioglitazone and/or liraglutide on pancreatic β-cells in db/db mice: Comparison of their effects between in an early and advanced stage of diabetes.
Topics: Animals; Apoptosis; Blood Glucose; Caspases; Cell Proliferation; Diabetes Mellitus, Type 2; Disease Models, Animal; Disease Progression; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Ki-67 Antigen; Liraglutide; Male; Mice; Mice, Transgenic; Organ Size; Pioglitazone; Proto-Oncogene Proteins c-bcl-2; RNA, Ribosomal, 18S; Thiazolidinediones; Time Factors; Triglycerides | 2015 |
Analysis of RNAseq datasets from a comparative infectious disease zebrafish model using GeneTiles bioinformatics.
Topics: Alternative Splicing; Animals; Disease Models, Animal; Fish Diseases; Fish Proteins; Gene Expression Profiling; Glucagon; High-Throughput Nucleotide Sequencing; Host-Pathogen Interactions; Larva; Metabolic Networks and Pathways; Molecular Sequence Annotation; Mycobacterium Infections, Nontuberculous; Mycobacterium marinum; Software; Staphylococcal Infections; Staphylococcus epidermidis; Transcriptome; Zebrafish | 2015 |
Coordinated changes in hepatic amino acid metabolism and endocrine signals support hepatic glucose production during fetal hypoglycemia.
Topics: Algorithms; Amino Acids; Animals; Biological Transport; Blood Glucose; Carbon Radioisotopes; Disease Models, Animal; Endocrine System Diseases; Female; Fetal Blood; Glucagon; Gluconeogenesis; Glutamic Acid; Glycine; Hydrocortisone; Hypoglycemia; Insulin; Liver; Sheep, Domestic; Up-Regulation | 2015 |
A Northern contaminant mixture impairs pancreas function in obese and lean JCR rats and inhibits insulin secretion in MIN6 cells.
Topics: Alcohol Drinking; Animals; Cell Death; Cell Line, Tumor; Complex Mixtures; Diabetes Mellitus; Disease Models, Animal; Dose-Response Relationship, Drug; Environmental Pollutants; Glucagon; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Male; Mice; Mitochondria; Obesity; Oxidative Stress; Pancreatic Neoplasms; Rats; Risk Assessment; Thinness | 2015 |
Pancreatic Neuroendocrine Tumors in Mice Deficient in Proglucagon-Derived Peptides.
Topics: Animals; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Glucagon; Glucagon-Like Peptide 1; Green Fluorescent Proteins; Humans; Immunohistochemistry; Islets of Langerhans; Liver Neoplasms; Mice; Mice, Knockout; Mice, Transgenic; Microscopy, Confocal; Neuroendocrine Tumors; Pancreatic Neoplasms; Proglucagon; Reverse Transcriptase Polymerase Chain Reaction | 2015 |
Glucose metabolism during fasting is altered in experimental porphobilinogen deaminase deficiency.
Topics: Animals; Cerebral Cortex; Disease Models, Animal; Fasting; Gene Expression; Gene Transfer Techniques; Genetic Therapy; Glucagon; Glucose; Homeostasis; Hydroxymethylbilane Synthase; Insulin; Liver; Male; Mice; Mice, Knockout; Porphyria, Acute Intermittent | 2016 |
Glucagon responses to exercise-induced hypoglycaemia are improved by somatostatin receptor type 2 antagonism in a rat model of diabetes.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Glucose; Hypoglycemia; Insulin; Liver; Male; Peptides, Cyclic; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Receptors, Somatostatin | 2016 |
Can somatostatin antagonism prevent hypoglycaemia during exercise in type 1 diabetes?
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Glucose; Hypoglycemia; Insulin; Liver; Male; Peptides, Cyclic; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Receptors, Somatostatin | 2016 |
Exenatide Treatment Alone Improves β-Cell Function in a Canine Model of Pre-Diabetes.
Topics: Animals; Blood Glucose; Body Composition; Disease Models, Animal; Dogs; Eating; Energy Metabolism; Exenatide; Fasting; Glucagon; Glucose Tolerance Test; Glycated Hemoglobin; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Secreting Cells; Liver; Male; Peptides; Prediabetic State; Venoms | 2016 |
Formononetin exhibits anti-hyperglycemic activity in alloxan-induced type 1 diabetic mice.
Topics: Alloxan; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Glucagon; Hypoglycemic Agents; Insulin; Islets of Langerhans; Isoflavones; Liver; Liver Glycogen; Male; Mice | 2017 |
The combined action of omega-3 polyunsaturated fatty acids and grape proanthocyanidins on a rat model of diet-induced metabolic alterations.
Topics: Adiponectin; Adiposity; Animals; Blood Glucose; Body Weight; Cholesterol; Diet; Dietary Supplements; Disease Models, Animal; Docosahexaenoic Acids; Eicosapentaenoic Acid; Female; Ghrelin; Glucagon; Insulin; Leptin; Metabolic Syndrome; Proanthocyanidins; Rats; Rats, Inbred WKY; Triglycerides; Vitis | 2016 |
Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease.
Topics: Animals; Atherosclerosis; Body Weight; Bone and Bones; Chemical Engineering; Cholesterol; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Combinations; Drug Delivery Systems; Drug Synergism; Glucagon; Hyperglycemia; Liver; Metabolic Diseases; Mice; Molecular Targeted Therapy; Non-alcoholic Fatty Liver Disease; Obesity; Triiodothyronine | 2016 |
Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAP-positive cells.
Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Gene Expression; Gene Expression Profiling; Glial Fibrillary Acidic Protein; Glucagon; Glucagonoma; Humans; Immunohistochemistry; Mice; Mice, Transgenic; N-Myc Proto-Oncogene Protein; Neuroendocrine Tumors; Pancreatic Neoplasms; Pituitary Neoplasms; Transcriptome | 2016 |
Antidepressant-like effects exerted by the intranasal administration of a glucagon-like peptide-2 derivative containing cell-penetrating peptides and a penetration-accelerating sequence in mice.
Topics: Administration, Intranasal; Animals; Antidepressive Agents; Brain; Cell-Penetrating Peptides; Depressive Disorder, Major; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 2; Mice | 2017 |
Aspartate inhibits LPS-induced MAFbx and MuRF1 expression in skeletal muscle in weaned pigs by regulating Akt, AMPKα and FOXO1.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Anti-Inflammatory Agents; Aspartic Acid; Cells, Cultured; Disease Models, Animal; F-Box Proteins; Forkhead Box Protein O1; Gene Expression Regulation; Glucagon; Humans; Hydrocortisone; Lipopolysaccharides; Muscle, Skeletal; Muscular Atrophy; Oncogene Protein v-akt; Paraspinal Muscles; Protein Kinases; Signal Transduction; SKP Cullin F-Box Protein Ligases; Swine; Tripartite Motif Proteins | 2017 |
Midgut-Derived Activin Regulates Glucagon-like Action in the Fat Body and Glycemic Control.
Topics: Activin Receptors; Activins; Animals; Carbohydrate Metabolism; Carrier Proteins; Dietary Carbohydrates; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Enteroendocrine Cells; Fat Body; Gastrointestinal Tract; Glucagon; Hepatocytes; Hyperglycemia; Insect Hormones; Larva; Mice; Oligopeptides; Pyrrolidonecarboxylic Acid; Receptors, Glucagon; RNA Interference; RNA, Messenger; Signal Transduction | 2017 |
The Characteristics of Hepatic Gsα-cAMP Axis in HSHF Diet-Fed Obese Insulin Resistance Rats and Genetic Diabetic Mice.
Topics: Animals; Blood Glucose; Cyclic AMP; Diabetes Mellitus; Diet, High-Fat; Dietary Sugars; Disease Models, Animal; Glucagon; GTP-Binding Protein alpha Subunits; Insulin; Insulin Resistance; Liver; Male; Mice, Inbred C57BL; Obesity; Rats, Wistar | 2017 |
Insulin acts as a powerful stimulator of axial myopia in chicks.
Topics: Actins; Amacrine Cells; Animals; Chickens; Cornea; Disease Models, Animal; Dose-Response Relationship, Drug; Early Growth Response Protein 1; Eye; Fluorescent Antibody Technique, Indirect; Glucagon; Glucose; Hyperopia; Hypoglycemic Agents; Injections; Insulin; Male; Myopia; Refraction, Ocular; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensory Deprivation; Vitreous Body | 2009 |
Effect of glucagon on amitriptyline-induced cardiovascular toxicity in rats.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Blood Pressure; Cardiovascular Diseases; Cardiovascular System; Disease Models, Animal; Electrocardiography; Gastrointestinal Agents; Glucagon; Heart Conduction System; Heart Rate; Infusions, Intravenous; Injections, Intravenous; Male; Rats; Rats, Wistar | 2008 |
Glucose replacement to euglycemia causes hypoxia, acidosis, and decreased insulin secretion in fetal sheep with intrauterine growth restriction.
Topics: Acidosis; Amino Acids; Animals; Blood Glucose; Carbon Dioxide; Disease Models, Animal; Down-Regulation; Female; Fetal Blood; Fetal Growth Retardation; Gestational Age; Glucagon; Glucose; Hydrogen-Ion Concentration; Hypoglycemia; Hypoxia; Infusions, Parenteral; Insulin; Insulin-Secreting Cells; Lactic Acid; Male; Oxygen; Pancreas; Placental Insufficiency; Pregnancy; Sheep; Time Factors | 2009 |
Opposite effects of glucagon and insulin on compensation for spectacle lenses in chicks.
Topics: Animals; Anterior Chamber; Chickens; Choroid; Contact Lenses; Disease Models, Animal; Drug Combinations; Eye; Glucagon; Glycosaminoglycans; Hormone Antagonists; Hormones; Hyperopia; Hypoglycemic Agents; Injections; Insulin; Insulin-Like Growth Factor I; Lens, Crystalline; Myopia; Sclera; Sensory Deprivation | 2009 |
Glucagon receptor signaling is essential for control of murine hepatocyte survival.
Topics: Animals; Apoptosis; Blotting, Western; Cell Survival; Cells, Cultured; Cricetinae; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Gastrointestinal Agents; Gene Expression; Glucagon; Hepatocytes; Liver Failure; Male; Mice; Mice, Inbred C57BL; Receptors, Glucagon; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction | 2008 |
Development and characterization of a novel rat model of type 2 diabetes mellitus: the UC Davis type 2 diabetes mellitus UCD-T2DM rat.
Topics: Adipokines; Adiposity; Age Factors; Aging; Animals; Blood Glucose; Crosses, Genetic; Diabetes Mellitus, Type 2; Disease Models, Animal; Disease Progression; Female; Fertility; Ghrelin; Glucagon; Glucose Intolerance; Insulin; Insulin Resistance; Insulin-Secreting Cells; Intra-Abdominal Fat; Lipids; Male; Obesity; Rats; Rats, Sprague-Dawley; Rats, Zucker; Triglycerides | 2008 |
The dipeptidyl peptidase IV inhibitor NVP-DPP728 reduces plasma glucagon concentration in cats.
Topics: Animals; Cats; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin; Insulin Secretion; Male; Nitriles; Pyrrolidines | 2010 |
Transgenic expression of insulin-response element binding protein-1 in beta-cells reproduces type 2 diabetes.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Glucagon-Secreting Cells; Glucose; Hyperinsulinism; Insulin; Insulin Resistance; Insulin-Secreting Cells; Iron Regulatory Protein 1; Mice; Mice, Transgenic; Obesity; Phenotype; Rats; Rats, Zucker; Somatostatin-Secreting Cells | 2009 |
Hypothalamic AMP-activated protein kinase activation with AICAR amplifies counterregulatory responses to hypoglycemia in a rodent model of type 1 diabetes.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Disease Models, Animal; Enzyme Activation; Enzyme Activators; Epinephrine; Glucagon; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Microinjections; Rats; Rats, Inbred BB; Rats, Sprague-Dawley; Ribonucleotides; RNA Interference; RNA, Small Interfering; Time Factors; Ventromedial Hypothalamic Nucleus | 2009 |
Pancreatic function of spontaneously diabetic torii rats in pre-diabetic stage.
Topics: Animals; Arginine; Benzoates; Body Weight; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Male; Obesity; Organ Culture Techniques; Pancreas; Peptide Fragments; Rats; Rats, Sprague-Dawley; Tolbutamide | 2009 |
Clozapine and quetiapine acutely reduce glucagon-like peptide-1 production and increase glucagon release in obese rats: implications for glucose metabolism and food choice behaviour.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Body Composition; Body Weight; Clozapine; Dibenzothiazepines; Dietary Fats; Disease Models, Animal; Eating; Exenatide; Food Preferences; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Tolerance Test; Hypoglycemic Agents; Insulin Resistance; Male; Obesity; Peptides; Pyrazines; Quetiapine Fumarate; Rats; Rats, Sprague-Dawley; Sitagliptin Phosphate; Triazoles; Venoms | 2009 |
Histological, immunocytochemical, and morphometrical analyses of pancreatic islets in the BSB mouse model of obesity.
Topics: Animals; Blood Glucose; Disease Models, Animal; Female; Glucagon; Immunohistochemistry; Insulin; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity | 2010 |
Age dependence of glucose tolerance in adult KK-Ay mice, a model of non-insulin dependent diabetes mellitus.
Topics: Age Factors; Amyloid; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 1; Glucose; Insulin; Islet Amyloid Polypeptide; Leptin; Male; Mice; Mice, Inbred ICR | 2009 |
Glucagon-like peptide-2 receptor modulates islet adaptation to metabolic stress in the ob/ob mouse.
Topics: Adaptation, Physiological; Animals; Blood Glucose; Body Weight; Cell Proliferation; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptide-2 Receptor; Glucose Intolerance; Glucose Tolerance Test; Hypoglycemia; Insulin; Islets of Langerhans; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Receptors, Glucagon; Signal Transduction; Stress, Physiological; Time Factors | 2010 |
Glucagon receptor antagonist-mediated improvements in glycemic control are dependent on functional pancreatic GLP-1 receptor.
Topics: Animals; Antibodies, Monoclonal; Disease Models, Animal; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose Tolerance Test; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Peptide Fragments; Receptors, Glucagon; Signal Transduction | 2010 |
Recurrent hypoglycemia increases hypothalamic glucose phosphorylation activity in rats.
Topics: Animals; Blood Glucose; Brain Chemistry; Disease Models, Animal; Epinephrine; Glucagon; Glucose; Hypoglycemia; Hypothalamus; Male; Phosphorylation; Rats; Rats, Sprague-Dawley; Recurrence | 2011 |
Neuro-endocrine basis for altered plasma glucose homeostasis in the Fragile X mouse.
Topics: Animals; Blood Glucose; Calcium Channels; Dietary Supplements; Disease Models, Animal; Fragile X Mental Retardation Protein; Fragile X Syndrome; Glucagon; Homeostasis; Humans; Hyperinsulinism; Insulin; Islets of Langerhans; Male; Mice; Mice, Knockout; Somatostatin; Taurine | 2010 |
Insulin-induced hypoglycemia increases hepatic sensitivity to glucagon in dogs.
Topics: 3-Hydroxybutyric Acid; AMP-Activated Protein Kinases; Animals; Diabetes Mellitus, Type 1; Disease Models, Animal; Dogs; Enzyme Activation; Fatty Acids, Nonesterified; Female; Glucagon; Gluconeogenesis; Glycogenolysis; Humans; Hypoglycemia; Insulin; Liver; Liver Glycogen; Male; Signal Transduction | 2010 |
Subcapsular fetal pig pancreas fragment transplantation provides normal blood glucose control in a preclinical model of diabetes.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Disease Models, Animal; Glucagon; Homeostasis; Humans; Pancreas; Pancreas Transplantation; Pancreatectomy; Swine; Transplantation, Heterologous | 2011 |
The reversal of diabetes in rat model using mouse insulin producing cells - a combination approach of tissue engineering and macroencapsulation.
Topics: Animals; Blood Glucose; Cell Differentiation; Diabetes Mellitus, Experimental; Disease Models, Animal; Fasting; Gelatin; Gene Expression Regulation; Glucagon; Glucose Tolerance Test; Insulin; Insulin-Secreting Cells; Islets of Langerhans Transplantation; Mice; Microscopy, Electron, Scanning; Polyurethanes; Povidone; Rats; Stem Cells; Tissue Engineering; Tissue Scaffolds; Tissue Survival | 2011 |
Sitagliptin lowers glucagon and improves glucose tolerance in prediabetic obese SHROB rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Feeding Behavior; Glucagon; Glucagon-Like Peptide 1; Glyburide; Hypoglycemic Agents; Insulin; Insulin Secretion; Pyrazines; Rats; Sitagliptin Phosphate; Triazoles | 2011 |
A diabetes drug, sitagliptin, also has a potential to prevent diabetes.
Topics: Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 1; Hypoglycemic Agents; Insulin; Insulin Secretion; Pyrazines; Rats; Sitagliptin Phosphate; Triazoles | 2011 |
Chronic treatment with a glucagon receptor antagonist lowers glucose and moderately raises circulating glucagon and glucagon-like peptide 1 without severe alpha cell hypertrophy in diet-induced obese mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dietary Fats; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Hypertrophy; In Vitro Techniques; Male; Mice; Mice, Knockout; Obesity; Receptors, Glucagon; Streptozocin | 2011 |
Functional and structural adaptations in the pancreatic α-cell and changes in glucagon signaling during protein malnutrition.
Topics: Animals; Calcium Signaling; Cells, Cultured; Diet, Protein-Restricted; Dietary Proteins; Disease Models, Animal; Female; Glucagon; Glucagon-Secreting Cells; Glucose; Glucose-6-Phosphatase; Insulin; Islets of Langerhans; Liver; Mice; Phosphoenolpyruvate; PPAR gamma; Protein-Energy Malnutrition; Signal Transduction | 2012 |
Regeneration of pancreatic non-β endocrine cells in adult mice following a single diabetes-inducing dose of streptozotocin.
Topics: Animals; Cell Count; Cell Proliferation; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Glucagon; Glucagon-Secreting Cells; Homeodomain Proteins; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Mice; Mice, Inbred C57BL; Regeneration; Somatostatin; Somatostatin-Secreting Cells; Streptozocin; Trans-Activators | 2012 |
Evidence of the receptor-mediated influence of melatonin on pancreatic glucagon secretion via the Gαq protein-coupled and PI3K signaling pathways.
Topics: Animals; Cell Line; Cyclic AMP; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Glucagon; Glucagon-Secreting Cells; GTP-Binding Protein alpha Subunits, Gq-G11; Liver; Male; Melanins; Mice; Mice, Knockout; Pertussis Toxin; Phosphatidylinositol 3-Kinase; Rats; Rats, Wistar; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Receptors, Glucagon; RNA, Messenger; Signal Transduction; Tetrahydronaphthalenes; Tissue Culture Techniques; Tryptamines; Type C Phospholipases | 2012 |
Discovery of a novel glucagon receptor antagonist N-[(4-{(1S)-1-[3-(3, 5-dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)-1H-pyrazol-1-yl]ethyl}phenyl)carbonyl]-β-alanine (MK-0893) for the treatment of type II diabetes.
Topics: Animals; Area Under Curve; beta-Alanine; Blood Glucose; CHO Cells; Cricetinae; Cricetulus; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Dogs; Glucagon; Glucagon-Like Peptide-1 Receptor; Humans; Inhibitory Concentration 50; Macaca mulatta; Mice; Mice, Obese; Microsomes, Liver; Pyrazoles; Rats; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I; Receptors, Vasoactive Intestinal Peptide, Type II; Receptors, Vasoactive Intestinal Polypeptide, Type I | 2012 |
Vision-guided ocular growth in a mutant chicken model with diminished visual acuity.
Topics: Amacrine Cells; Animals; Axial Length, Eye; Chickens; Disease Models, Animal; Early Growth Response Protein 1; Eye; Fluorescent Antibody Technique, Indirect; Glucagon; Heterotrimeric GTP-Binding Proteins; Microscopy, Confocal; Myopia; Refraction, Ocular; Retinoscopy; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensory Deprivation; Ultrasonography; Vision Disorders; Vision, Ocular; Visual Acuity | 2012 |
Glucose metabolism and pancreatic defects in spinal muscular atrophy.
Topics: Age Factors; Animals; Animals, Newborn; Apoptosis; Blood Glucose; Cell Proliferation; Disease Models, Animal; Glucagon; Glucose Metabolism Disorders; Humans; In Situ Nick-End Labeling; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Pancreatic Diseases; Spinal Muscular Atrophies of Childhood; Survival of Motor Neuron 1 Protein | 2012 |
Glucagon receptor is required for long-term survival: a natural history study of the Mahvash disease in a murine model.
Topics: Animals; Blood Glucose; Cachexia; Disease Models, Animal; Disease Progression; Female; Glucagon; Humans; Hypoglycemia; Lethargy; Liver Neoplasms; Longevity; Male; Mice; Mice, Inbred DBA; Mice, Knockout; Neoplastic Syndromes, Hereditary; Neuroectodermal Tumors, Primitive, Peripheral; Pancreatic Neoplasms; Receptors, Glucagon; Skin Neoplasms | 2012 |
Abnormal endocrine pancreas function at birth in cystic fibrosis ferrets.
Topics: Animals; Animals, Newborn; Apoptosis; Cells, Cultured; Cystic Fibrosis; Diabetes Mellitus; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Female; Ferrets; Fibrosis; Gene Knockout Techniques; Glucagon; Glucose; Glucose Intolerance; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Male; Pancreas, Exocrine; Pancreatic Ducts; Pancreatitis; Species Specificity | 2012 |
The effect of glucagon and cyclic adenosine monophosphate on acute liver damage induced by acetaminophen.
Topics: Acetaminophen; Acute Disease; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cyclic AMP; Disease Models, Animal; Dose-Response Relationship, Drug; Glucagon; Glutathione; Injections, Intraperitoneal; Liver; Male; Mice; Mice, Inbred CBA; NF-kappa B; Nitric Oxide Synthase Type II | 2013 |
Alterations in glucose homeostasis in a murine model of Chagas disease.
Topics: Adipose Tissue, White; Animals; Blood Glucose; Chagas Disease; Disease Models, Animal; Fluorescent Antibody Technique; Glucagon; Gluconeogenesis; Glucose; Homeostasis; Insulin; Liver; Male; Mice; Pancreas; Trypanosoma cruzi | 2013 |
Somatostatin inhibits glucagon-like peptide-1-induced insulin secretion and proliferation of RINm5F insulinoma cells.
Topics: Animals; Cell Division; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Drug Interactions; Glucagon; Glucagon-Like Peptide 1; Insulin; Insulin Secretion; Insulinoma; Pancreatic Neoplasms; Peptide Fragments; Protein Precursors; Rats; Somatostatin; Transcription Factors; Tumor Cells, Cultured | 2002 |
Insulin and glucagon impairments in relation with islet cells morphological modifications following long term pancreatic duct ligation in the rabbit--a model of non-insulin-dependent diabetes.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Insulin; Islets of Langerhans; Male; Pancreatic Ducts; Rabbits; Time Factors | 2001 |
The role of autoimmunity in islet allograft destruction: major histocompatibility complex class II matching is necessary for autoimmune destruction of allogeneic islet transplants after T-cell costimulatory blockade.
Topics: Animals; Autoimmune Diseases; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Glucagon; Graft Survival; Histocompatibility Antigens Class II; Histocompatibility Testing; Insulin; Islets of Langerhans Transplantation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Inbred Strains; Species Specificity; T-Lymphocytes; Time Factors; Transplantation, Homologous | 2002 |
Uncoupling protein 2 knockout mice have enhanced insulin secretory capacity after a high-fat diet.
Topics: Animals; Base Sequence; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Fats; Disease Models, Animal; DNA Primers; Fatty Acids, Nonesterified; Glucagon; Insulin; Insulin Secretion; Ion Channels; Membrane Transport Proteins; Mice; Mice, Knockout; Mitochondrial Proteins; Proteins; Triglycerides; Uncoupling Protein 2; Weight Gain | 2002 |
Huntington's disease of the endocrine pancreas: insulin deficiency and diabetes mellitus due to impaired insulin gene expression.
Topics: Aging; Animals; Blood Glucose; Blotting, Northern; Blotting, Western; Calcium; Diabetes Mellitus; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Glucagon; Glucose Intolerance; Huntingtin Protein; Huntington Disease; Immunohistochemistry; Insulin; Islets of Langerhans; Mice; Mice, Transgenic; Nerve Tissue Proteins; Nuclear Proteins; RNA, Messenger; Somatostatin; Transcription Factors | 2002 |
Chronic cadmium treatment induces islet B cell injury in ovariectomized cynomolgus monkeys.
Topics: Animals; Blood Glucose; Cadmium; Cadmium Poisoning; Disease Models, Animal; Female; Glucagon; Insulin; Islets of Langerhans; Macaca fascicularis; Metallothionein; Monkey Diseases; Ovariectomy; Random Allocation | 2003 |
PACAP is expressed in secretory granules of insulin and glucagon cells in human and rodent pancreas. Evidence for generation of cAMP compartments uncoupled from hormone release in diabetic islets.
Topics: Animals; Colforsin; Cyclic AMP; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Glucagon; Glucose; Humans; Immunohistochemistry; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Microscopy, Immunoelectron; Neuropeptides; Pancreas; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Wistar | 2003 |
Glucagon-like peptide 1 receptor agonist ZP10A increases insulin mRNA expression and prevents diabetic progression in db/db mice.
Topics: Animals; Blood Glucose; Carrier Proteins; Diabetes Mellitus; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Mice; Mice, Inbred C57BL; Peptide Fragments; Peptides; Protein Precursors; Receptors, Glucagon; RNA, Messenger | 2003 |
The role of I(1)-imidazoline receptors and alpha(2)-adrenergic receptors in the modulation of glucose and lipid metabolism in the SHROB model of metabolic syndrome X.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Benzofurans; Blood Pressure; Disease Models, Animal; Female; Glucagon; Glucose; Glucose Tolerance Test; Humans; Imidazoles; Imidazoline Receptors; Lipid Metabolism; Male; Metabolic Syndrome; Obesity; Oxazoles; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha-2; Receptors, Drug; Rilmenidine; Yohimbine | 2003 |
Effects of centrally injected GLP-1 in various experimental models of gastric mucosal damage.
Topics: Animals; Disease Models, Animal; Female; Gastric Acidity Determination; Gastric Mucosa; Glucagon; Glucagon-Like Peptide 1; Hydrogen-Ion Concentration; Injections; Peptide Fragments; Protein Precursors; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 2004 |
Effect of duodenal-jejunal exclusion in a non-obese animal model of type 2 diabetes: a new perspective for an old disease.
Topics: Anastomosis, Surgical; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Duodenum; Female; Follow-Up Studies; Gastric Bypass; Glucagon; Glucagon-Like Peptide 1; Jejunum; Male; Peptide Fragments; Protein Precursors; Rats; Rats, Inbred Strains | 2004 |
Recombinant glucagon-like peptide-1 increases myocardial glucose uptake and improves left ventricular performance in conscious dogs with pacing-induced dilated cardiomyopathy.
Topics: Animals; Blood Glucose; Cardiac Pacing, Artificial; Cardiomyopathy, Dilated; Consciousness; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Energy Metabolism; Fatty Acids; Female; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Clamp Technique; Heart Failure; Hemodynamics; Hyperinsulinism; Infusions, Intravenous; Insulin Resistance; Male; Myocardium; Oxygen Consumption; Peptide Fragments; Protein Precursors; Recombinant Proteins; Ventricular Dysfunction, Left | 2004 |
Glucagon-like peptide-1 limits myocardial stunning following brief coronary occlusion and reperfusion in conscious canines.
Topics: Animals; Coronary Circulation; Disease Models, Animal; Dogs; Glucagon; Glucagon-Like Peptide 1; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardial Stunning; Peptide Fragments; Protein Precursors | 2005 |
Reduction of beta cell mass: partial insulin secretory compensation from the residual beta cell population in the nicotinamide-streptozotocin Göttingen minipig after oral glucose in vivo and in the perfused pancreas.
Topics: Animals; Area Under Curve; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Fasting; Glucagon; Glucagon-Like Peptide 1; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Niacinamide; Pancreas; Peptide Fragments; Perfusion; Protein Precursors; Reference Values; Swine; Swine, Miniature | 2004 |
Effects of surface gastric pacing on gastric myoelectrical activity and plasma motilin in a canine model of gastric motility disorders.
Topics: Animals; Disease Models, Animal; Dogs; Electric Stimulation; Fasting; Female; Gastrointestinal Motility; Glucagon; Male; Motilin; Stomach | 2004 |
Glucagon-like peptide 1 can directly protect the heart against ischemia/reperfusion injury.
Topics: Animals; Blood Pressure; Butadienes; Chromones; Disease Models, Animal; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Heart Rate; In Vitro Techniques; Insulin; Insulin Secretion; Male; MAP Kinase Signaling System; Morpholines; Myocardial Infarction; Myocardial Reperfusion Injury; Nitriles; Peptide Fragments; Phosphoinositide-3 Kinase Inhibitors; Protein Precursors; Rats; Rats, Sprague-Dawley; Time Factors | 2005 |
Hormonal and metabolic defects in a prader-willi syndrome mouse model with neonatal failure to thrive.
Topics: Aging; Animals; Animals, Newborn; Body Weight; Disease Models, Animal; DNA Primers; Exons; Failure to Thrive; Fetus; Gene Deletion; Glucagon; Hormones; Insulin; Liver Glycogen; Mice; Mice, Transgenic; Prader-Willi Syndrome; Reverse Transcriptase Polymerase Chain Reaction | 2005 |
VGF ablation blocks the development of hyperinsulinemia and hyperglycemia in several mouse models of obesity.
Topics: Adipose Tissue; Animals; Diet; Disease Models, Animal; Disease Susceptibility; Energy Intake; Glucagon; Glucose; Homeostasis; Hyperglycemia; Hyperinsulinism; Hypoglycemia; Injections, Intraperitoneal; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Growth Factors; Neuropeptides; Obesity; Proteins; Receptor, Melanocortin, Type 4 | 2005 |
Development of islet-like cell clusters after pancreas transplantation in the spontaneously diabetic Torri rat.
Topics: Age of Onset; Animals; Blotting, Western; Cell Nucleus; Cell Proliferation; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Glucose; Glucose Tolerance Test; Homeodomain Proteins; Immunohistochemistry; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Islets of Langerhans Transplantation; Ki-67 Antigen; Male; Pancreas; Pancreas Transplantation; Rats; Time Factors; Trans-Activators | 2005 |
Glucagon receptor agonists and antagonists affect the growth of the chick eye: a role for glucagonergic regulation of emmetropization?
Topics: Animals; Chickens; Choroid; Disease Models, Animal; Eye; Fluorescent Antibody Technique, Indirect; Glucagon; Injections; Male; Myopia; Ocular Physiological Phenomena; Photoreceptor Cells, Vertebrate; Receptors, Glucagon; Sensory Deprivation; Vitreous Body | 2005 |
Glucagon- and secretin-related peptides differentially alter ocular growth and the development of form-deprivation myopia in chicks.
Topics: Animals; Chickens; Disease Models, Animal; Dose-Response Relationship, Drug; Eye; Fluorescent Antibody Technique, Indirect; Glucagon; Injections; Male; Myopia; Peptide Fragments; Retina; Secretin; Sensory Deprivation; Ultrasonography; Vitreous Body | 2005 |
p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis.
Topics: Acetylcysteine; Adenoviridae; Animals; Cell Line, Tumor; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Type 1; Disease Models, Animal; Enzyme Inhibitors; Gene Silencing; Glucagon; Gluconeogenesis; Glucose; Glucose-6-Phosphatase; Hepatocytes; Imidazoles; Liver; Mice; p38 Mitogen-Activated Protein Kinases; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphoenolpyruvate Carboxykinase (GTP); Phosphorylation; Promoter Regions, Genetic; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Streptozocin; Trans-Activators; Transcription Factors; Transfection | 2005 |
A model of controlled acute hyperglycemia in rats: Effects of insulin and glucagon-like peptide-1 analog.
Topics: Acute Disease; Anesthesia; Animals; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 1; Glucose; Growth Hormone; Hyperglycemia; Insulin; Male; Rats; Rats, Sprague-Dawley | 2006 |
ZENK expression of retinal glucagon amacrine cells in chicks: the effect of defocus presented in vivo, in vitro and under anesthesia.
Topics: Aging; Amacrine Cells; Anesthesia; Animals; Awareness; Chickens; Disease Models, Animal; Eye; Eye Proteins; Glucagon; In Vitro Techniques; Male; Photic Stimulation; Refraction, Ocular; Refractive Errors; Transcription Factors | 2006 |
Attenuated insulin release and storage in fetal sheep pancreatic islets with intrauterine growth restriction.
Topics: Animals; Arginine; Body Temperature; Catecholamines; Disease Models, Animal; Female; Fetal Growth Retardation; Glucagon; Glucose; Hydrocortisone; Insulin; Islets of Langerhans; Norepinephrine; Organ Size; Oxygen; Potassium Chloride; Pregnancy; Pregnancy, Animal; Sheep | 2006 |
Insulin resistance causes increased beta-cell mass but defective glucose-stimulated insulin secretion in a murine model of type 2 diabetes.
Topics: Animals; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Type 2; Dietary Sucrose; Disease Models, Animal; Glucagon; Glucose; Homeostasis; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Mice; Mice, Inbred Strains; Receptor, Insulin | 2006 |
Feeding and neuroendocrine responses after recurrent insulin-induced hypoglycemia.
Topics: Adaptation, Physiological; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Blood Glucose; Catecholamines; Corticosterone; Disease Models, Animal; Eating; Feeding Behavior; Glucagon; Hunger; Hyperphagia; Hypoglycemia; Insulin; Male; Rats; Rats, Sprague-Dawley | 2006 |
A comparison of vasopressin and glucagon in beta-blocker induced toxicity.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Disease Models, Animal; Glucagon; Heart Rate; Hemodynamics; Poisoning; Propranolol; Survival Rate; Swine; Vasoconstrictor Agents; Vasopressins | 2006 |
I.c.v. administration of the nonsteroidal glucocorticoid receptor antagonist, CP-472555, prevents exacerbated hypoglycemia during repeated insulin administration.
Topics: Animals; Autonomic Nervous System; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Epinephrine; Glucagon; Hypoglycemia; Hypoglycemic Agents; Hypothalamus; Insulin; Male; Neurosecretory Systems; Phenanthrenes; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Transcriptional Activation | 2006 |
Glucagon-related peptides in the mouse retina and the effects of deprivation of form vision.
Topics: Animals; Disease Models, Animal; Early Growth Response Protein 1; Fluorescent Antibody Technique, Indirect; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptides; Growth Hormone-Releasing Hormone; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Myopia; Peptide PHI; Pituitary Adenylate Cyclase-Activating Polypeptide; Retina; Sensory Deprivation; Vasoactive Intestinal Peptide | 2007 |
Chronic fetal hypoglycemia inhibits the later steps of stimulus-secretion coupling in pancreatic beta-cells.
Topics: Animals; Disease Models, Animal; Female; Fetal Growth Retardation; Fetus; Glucagon; Glucose; Hypoglycemia; Immunohistochemistry; Insulin; Insulin Secretion; Insulin-Secreting Cells; Microscopy, Electron; Pancreas; Pregnancy; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; Sheep | 2007 |
Effects of cyclooxygenase-2 inhibitor on glucagon-induced delayed gastric emptying and gastric dysrhythmia in dogs.
Topics: Animals; Blood Glucose; Celecoxib; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Dogs; Female; Gastric Emptying; Gastrointestinal Motility; Gastroparesis; Glucagon; Pyloric Antrum; Pyrazoles; Sulfonamides | 2007 |
Somatostatin receptor subtype-2-deficient mice with diet-induced obesity have hyperglycemia, nonfasting hyperglucagonemia, and decreased hepatic glycogen deposition.
Topics: Animal Feed; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Gluconeogenesis; Glycogen; Glycogen Synthase; Glycogenolysis; Homeostasis; Hyperglycemia; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Obese; Obesity; Receptors, Somatostatin; Triglycerides | 2007 |
The effects of duodenal-jejunal exclusion on hormonal regulation of glucose metabolism in Goto-Kakizaki rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Gastric Bypass; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Homeostasis; Insulin; Leptin; Male; Rats; Rats, Inbred Strains | 2007 |
An assessment of the in vivo efficacy of the glycogen phosphorylase inhibitor GPi688 in rat models of hyperglycaemia.
Topics: Animals; Blood Glucose; Disease Models, Animal; Dose-Response Relationship, Drug; Glucagon; Glucose; Glucose Tolerance Test; Glycogen Phosphorylase; Glycogen Synthase; Hepatocytes; Hyperglycemia; Inhibitory Concentration 50; Male; Obesity; Quinolones; Rats; Rats, Wistar; Rats, Zucker; Thiophenes | 2007 |
[Effect of pineal gland peptides on morphofunctional structure of the pancreas in ageing].
Topics: Aging, Premature; Animals; Disease Models, Animal; Glucagon; Male; Oligopeptides; Pancreas; Peptides; Pineal Gland; Rats; Rats, Wistar; Somatostatin | 2007 |
Insulin alters cytokine content in two pivotal organs after brain death: a porcine model.
Topics: Animals; Blood Glucose; Brain Death; Catecholamines; Clinical Protocols; Cytokines; Disease Models, Animal; Fatty Acids, Nonesterified; Glucagon; Insulin; Kidney; Liver; Myocardium; Reverse Transcriptase Polymerase Chain Reaction; Swine | 2008 |
Islet secretion in a new experimental model for non-insulin-dependent diabetes.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isoproterenol; Male; Pregnancy; Rats; Somatostatin; Theophylline; Tolbutamide | 1981 |
Experimental gallstone pancreatitis. Pathogenesis and response to different treatment modalities.
Topics: Albumins; Amylases; Animals; Cholelithiasis; Disease Models, Animal; Dogs; Glucagon; Hematocrit; In Vitro Techniques; Pancreas; Pancreatitis; Protease Inhibitors; Steroids | 1982 |
Lactogenic and somatotropic binding sites in liver membranes of rats with renal insufficiency.
Topics: Animals; Cell Membrane; Creatinine; Disease Models, Animal; Female; Glucagon; Growth Hormone; Insulin; Kidney Failure, Chronic; Liver; Nucleotidases; Prolactin; Rats; Receptors, Cell Surface | 1980 |
Hormonal enhancement of technetium-99m pertechnetate uptake in experimental Meckel's diverticulum.
Topics: Animals; Disease Models, Animal; Dogs; Gastric Mucosa; Glucagon; Meckel Diverticulum; Pentagastrin; Radionuclide Imaging; Sodium Pertechnetate Tc 99m; Technetium | 1980 |
Impairment of hormone-stimulated cardiac adenylate cyclase activity in the genetically obese (fa/fa) Zucker rat.
Topics: Adenylyl Cyclases; Age Factors; Animals; Disease Models, Animal; Enzyme Activation; Food Deprivation; Glucagon; Isoproterenol; Myocardium; Obesity; Rats; Receptors, Cell Surface; Secretin; Vasoactive Intestinal Peptide | 1981 |
Effect of hormones on hepatocyte gluconeogenesis in different models of acute uraemia.
Topics: Acute Kidney Injury; Animals; Blood Glucose; Bucladesine; Dihydroxyacetone; Disease Models, Animal; Epinephrine; Female; Glucagon; Gluconeogenesis; Hormones; Insulin; Liver; Propranolol; Pyruvates; Rats; Rats, Inbred Strains; Uremia | 1982 |
A conscious septic dog model with hemodynamic and metabolic responses similar to responses of humans.
Topics: Animals; Catecholamines; Disease Models, Animal; Dogs; Escherichia coli Infections; Glucagon; Hemodynamics; Infections; Insulin | 1984 |
Portacaval anastomosis: brain and plasma metabolite abnormalities and the effect of nutritional therapy.
Topics: Amino Acids; Animals; Brain; Disease Models, Animal; Glucagon; Insulin; Liver Diseases; Male; Nutritional Physiological Phenomena; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains; Species Specificity; Tryptophan | 1984 |
Time course of serum glucoregulatory variables and lipids following neonatal thymectomy of diabetes-prone and control BB Wistar rats fed a defined diet.
Topics: Animals; Animals, Newborn; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Food, Formulated; Glucagon; Insulin; Male; Rats; Rats, Inbred Strains; Thymectomy | 1984 |
Chronic hyperinsulinemia in the fetal rhesus monkey: effects of physiologic hyperinsulinemia on fetal substrates, hormones, and hepatic enzymes.
Topics: Amino Acids; Animals; Blood Glucose; Disease Models, Animal; Erythropoietin; Female; Fetus; Glucagon; Insulin; Liver; Macaca mulatta; Maternal-Fetal Exchange; Pregnancy; Pregnancy in Diabetics | 1984 |
Glucose kinetics, plasma metabolites, and endocrine responses during experimental ketosis in steers.
Topics: Acidosis; Animals; Blood Glucose; Cattle; Cattle Diseases; Disease Models, Animal; Fatty Acids, Nonesterified; Glucagon; Glucose; Growth Hormone; Insulin; Ketone Bodies; Ketosis; Male | 1984 |
[Acute hepatic failure, with special reference to its treatment].
Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Animals; Blood Transfusion; Brain Edema; Child; Child, Preschool; Disease Models, Animal; Female; Glucagon; Hepatic Encephalopathy; Hepatitis B Surface Antigens; Humans; Infant; Insulin; Japan; Liver Diseases; Male; Middle Aged; Pregnancy; Prognosis; Rabbits; Rats; Tomography, X-Ray Computed | 1982 |
The Chinese hamster as a model for the study of diabetes mellitus.
Topics: Animals; Blood Glucose; Cricetinae; Cricetulus; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Insulin; Pancreas | 1982 |
Short-term influences of dichloroacetate on genetically hyperlipemic rats.
Topics: Acetates; Animals; Dichloroacetic Acid; Disease Models, Animal; Fatty Acids, Nonesterified; Glucagon; Hyperlipidemias; Hypoglycemia; Insulin; Ketone Bodies; Obesity; Rats; Triglycerides | 1980 |
Metabolic consequences of fasting in old lean and obese Zucker rats.
Topics: Animals; Carbohydrate Metabolism; Cholesterol; Disease Models, Animal; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Glycogen; Insulin; Lipid Metabolism; Liver; Male; Obesity; Phospholipids; Rats; Sex Factors; Triglycerides | 1980 |
Experimental dumping: mesenteric blood flow and fluid exchange.
Topics: Animals; Antigens; Disease Models, Animal; Dogs; Dumping Syndrome; Gastrins; Glucagon; Insulin; Intestinal Secretions; Intestines; Mesentery; Regional Blood Flow; Water-Electrolyte Balance | 1980 |
Depression of glucose utilization by Intralipid in the post-traumatic period: an experimental study.
Topics: Animals; Antigens; Blood Glucose; Chylomicrons; Depression, Chemical; Disease Models, Animal; Dogs; Epinephrine; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Insulin; Norepinephrine; Time Factors; Wounds and Injuries | 1980 |
Endotoxin-induced hyperinsulinemia and hyperglucagonemia after experimental liver injury.
Topics: Animals; Carbon Tetrachloride Poisoning; Disease Models, Animal; Endotoxins; Galactosamine; Glucagon; Hepatectomy; Hyperinsulinism; Liver Diseases; Male; Rats; Salmonella enteritidis | 1981 |
Dynamic time course studies of the spontaneously diabetic BB Wistar rat. III. Light-microscopic and ultrastructural observations of pancreatic islets of Langerhans.
Topics: Animals; Diabetes Mellitus; Disease Models, Animal; Glucagon; Immunoenzyme Techniques; Insulin; Islets of Langerhans; Rats; Rats, Inbred Strains | 1982 |
Characterization of insulin-dependent diabetes mellitus induced by a new variant (DK-27) of encephalomyocarditis virus in DBA/2 mice.
Topics: Animals; Blood Glucose; Cardiovirus Infections; Diabetes Mellitus, Type 1; Disease Models, Animal; Encephalomyocarditis virus; Glucagon; Glycated Hemoglobin; Hyperglycemia; Insulin; Male; Mice; Mice, Inbred DBA; Pancreas; Virus Replication | 1995 |
Endocrine changes and metabolic responses in a validated canine brain death model.
Topics: Acidosis, Lactic; Adrenocorticotropic Hormone; Animals; Brain Death; Catecholamines; Diabetes Insipidus; Disease Models, Animal; Dogs; Glucagon; Hematocrit; Male; Reproducibility of Results; Thyroid Hormones; Time Factors; Vasopressins | 1995 |
The possible role of age-related increase in the plasma glucagon/insulin ratio in the enhanced hepatic gluconeogenesis and hyperglycemia in genetically diabetic (C57BL/KsJ-db/db) mice.
Topics: Age Factors; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Fructose-Bisphosphatase; Glucagon; Gluconeogenesis; Glucose-6-Phosphatase; Hyperglycemia; Insulin; Liver; Mice; Mice, Inbred C57BL | 1994 |
Effect of lithium on plasma glucose, insulin and glucagon in normal and streptozotocin-diabetic rats: role of glucagon in the hyperglycaemic response.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Hyperglycemia; Insulin; Lithium; Male; Rats; Rats, Wistar | 1994 |
Hormonal profiles in a canine model of the brain-dead organ donor.
Topics: Analysis of Variance; Animals; Blood Glucose; Brain Death; Catecholamines; Disease Models, Animal; Dogs; Evaluation Studies as Topic; Glucagon; Hemodynamics; Homeostasis; Hydrocortisone; Insulin; Intracranial Pressure; Male; Thyroid Hormones; Time Factors; Tissue Donors | 1994 |
Effect of subcutaneous Escherichia coli-induced hypermetabolic sepsis on hepatic gluconeogenesis and its hormonal responsiveness in the rat.
Topics: Animals; Dinoprost; Disease Models, Animal; Escherichia coli Infections; Glucagon; Gluconeogenesis; Hormones; In Vitro Techniques; Injections, Subcutaneous; Kinetics; Liver; Male; Perfusion; Rats; Rats, Sprague-Dawley; Vasopressins | 1993 |
Insulin is a superior antidote for cardiovascular toxicity induced by verapamil in the anesthetized canine.
Topics: Anesthesia; Animals; Antidotes; Blood Glucose; Cardiovascular Diseases; Disease Models, Animal; Dogs; Electrolytes; Epinephrine; Female; Glucagon; Heart; Hemodynamics; Insulin; Lactates; Lactic Acid; Male; Reproducibility of Results; Verapamil | 1993 |
Hemodynamic characterization in experimental liver cirrhosis induced by thioacetamide administration.
Topics: Anesthesia, General; Animals; Disease Models, Animal; Glucagon; Hemodynamics; Hypertension, Portal; Liver Cirrhosis, Experimental; Male; Pentobarbital; Rats; Rats, Wistar; Splanchnic Circulation; Thioacetamide | 1993 |
Myocardial glucose transporters and glycolytic metabolism during ischemia in hyperglycemic diabetic swine.
Topics: Animals; Coronary Vessels; Deoxyglucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glucose Transporter Type 4; Glycolysis; Hyperglycemia; Lactates; Microspheres; Monosaccharide Transport Proteins; Muscle Proteins; Myocardial Ischemia; Myocardium; Regional Blood Flow; Streptozocin; Swine | 1994 |
Development of colonic and pancreatic endocrine tumours in mice expressing a glucagon-SV40 T antigen transgene.
Topics: Adenoma, Islet Cell; Age Factors; Animals; Antigens, Polyomavirus Transforming; Colonic Neoplasms; Disease Models, Animal; Glucagon; Mice; Mice, Transgenic; Microscopy, Electron; Pancreatic Neoplasms | 1996 |
Hormonal and hemodynamic changes in a validated animal model of brain death.
Topics: Adrenocorticotropic Hormone; Animals; Brain Death; Catecholamines; Disease Models, Animal; Dogs; Electrocardiography; Glucagon; Hemodynamics; Male; Myocardium; Prospective Studies; Vasopressins | 1996 |
Experimental study of the detrimental effect of dopamine/glucagon combination in d,l-propranolol intoxication.
Topics: Adrenergic beta-Antagonists; Animals; Blood Gas Analysis; Blood Pressure; Calcium; Disease Models, Animal; Dopamine; Drug Interactions; Drug Overdose; Glucagon; Heart Rate; Lactates; Male; Partial Pressure; Propranolol; Rabbits; Random Allocation; Rats; Rats, Wistar; Respiration, Artificial; Respiratory Insufficiency; Species Specificity; Specific Pathogen-Free Organisms; Stereoisomerism; Ventricular Function, Left | 1996 |
Metabolic and endocrine effects of interleukin-1 in obese, diabetic Zucker fa/fa rats.
Topics: Animals; Blood Glucose; Cholesterol; Corticosterone; Diabetes Mellitus; Diabetes Mellitus, Type 2; Disease Models, Animal; Fatty Acids, Nonesterified; Glucagon; Humans; Injections, Intraperitoneal; Insulin; Interleukin-1; Lactic Acid; Lipid Metabolism; Lipids; Male; Obesity; Rats; Rats, Zucker; Recombinant Proteins; Time Factors; Triglycerides | 1996 |
Pancreatic A-cell function in the partially pancreatectomized Otsuka Long-Evans Tokushima Fatty rat, a model of spontaneous non-insulin-dependent diabetes mellitus.
Topics: Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Insulin; Islets of Langerhans; Male; Niacinamide; Organ Size; Pancreatectomy; Rats | 1996 |
[The limits of resection in hepatopancreatectomies in rats].
Topics: Animals; Bilirubin; Disease Models, Animal; Glucagon; Hepatectomy; Insulin; Liver; Liver Regeneration; Male; Pancreas; Pancreatectomy; Prognosis; Rats; Rats, Wistar; Regeneration; Safety; Survival Rate | 1996 |
Incretin hormone expression in the gut of diabetic mice and rats.
Topics: Animals; Blotting, Northern; Colon; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Gastric Inhibitory Polypeptide; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Intestinal Mucosa; Intestine, Small; Intestines; Mice; Mice, Inbred NOD; Peptide Fragments; Proglucagon; Protein Precursors; Rats; Rats, Zucker; Rectum; RNA, Messenger; Tissue Distribution | 1997 |
alpha-Cell neogenesis in an animal model of IDDM.
Topics: Animals; Antimetabolites; Bromodeoxyuridine; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Glucagon; Guinea Pigs; Homeodomain Proteins; Immune Sera; Immunohistochemistry; Insulin; Male; Mice; Mice, Inbred NOD; Neuropeptide Y; Pancreatic Ducts; Rabbits; Rats; Regeneration; Trans-Activators; Tyrosine 3-Monooxygenase | 1997 |
Insulin improves survival in a canine model of acute beta-blocker toxicity.
Topics: Acute Disease; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Antidotes; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Drug Monitoring; Epinephrine; Glucagon; Hemodynamics; Hypoglycemic Agents; Insulin; Poisoning; Propranolol; Survival Analysis | 1997 |
Demonstration of two different processes of beta-cell regeneration in a new diabetic mouse model induced by selective perfusion of alloxan.
Topics: Alloxan; Animals; Blood Glucose; Body Weight; Cell Division; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Glucose Tolerance Test; Homeodomain Proteins; Immunohistochemistry; Insulin; Islets of Langerhans; Keratins; Male; Mice; Mice, Inbred ICR; Pancreatic Polypeptide; Perfusion; Regeneration; Somatostatin; Time Factors; Trans-Activators | 1997 |
Impaired development of pancreatic beta-cell mass is a primary event during the progression to diabetes in the GK rat.
Topics: Age Factors; Animals; Animals, Newborn; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Disease Progression; Female; Glucagon; Guinea Pigs; Immunoglobulin G; Immunohistochemistry; Insulin; Islets of Langerhans; Male; Microscopy, Confocal; Organ Size; Pregnancy; Rabbits; Rats; Rats, Inbred Strains; Rats, Wistar | 1997 |
Insulin for beta-blocker toxicity.
Topics: Adrenergic beta-Antagonists; Animals; Disease Models, Animal; Dogs; Glucagon; Humans; Hypoglycemic Agents; Insulin; Poisoning | 1997 |
Alterations of insulin and glucagon secretion from the perfused pancreas before, at the onset and after the development of diabetes in male Otsuka Long-Evans Tokushima Fatty (OLETF) rats.
Topics: Animals; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Glucose; Immunohistochemistry; Insulin; Insulin Secretion; Male; Obesity; Pancreas; Perfusion; Rats; Rats, Inbred Strains; Time Factors | 1997 |
Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat.
Topics: Animals; Apoptosis; Cohort Studies; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Glucagon; Glucose; Glucose Intolerance; Glucose Tolerance Test; Immunohistochemistry; In Vitro Techniques; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Pancreatic Polypeptide; Perfusion; Rats; Rats, Zucker; Somatostatin; Time Factors | 1998 |
Application of hepatic tolerance tests to the functional reserve assessment in rat models of fatty liver.
Topics: Animals; Cholesterol; Cholesterol, Dietary; Choline Deficiency; Cyclic AMP; Disease Models, Animal; Ethionine; Fatty Liver; Galactosemias; Glucagon; Half-Life; Hepatectomy; Indocyanine Green; Liver; Liver Function Tests; Male; Phospholipids; Rats; Rats, Sprague-Dawley | 1998 |
Metabolic adaptation to experimentally increased glucose demand in ruminants.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Blood Urea Nitrogen; Disease Models, Animal; Fatty Acids, Nonesterified; Glucagon; Gluconeogenesis; Glucose; Glycosuria; Hydrocortisone; Insulin; Liver; Male; Phlorhizin; Sheep; Sheep Diseases; Thyroxine; Triiodothyronine | 1998 |
Glucagon ameliorates pancreatic subcellular redistribution of lysosomal enzyme in rats with acute pancreatitis of closed duodenal loop.
Topics: Acute Disease; Amylases; Analysis of Variance; Animals; Body Water; Cathepsin B; Disease Models, Animal; Duodenum; Glucagon; Injections, Subcutaneous; Lysosomes; Male; Pancreas; Pancreatitis; Rats; Rats, Wistar; Reference Values; Statistics, Nonparametric; Trypsin | 1999 |
A new mouse model of spontaneous diabetes derived from ddY strain.
Topics: Animals; Blood Glucose; Cholesterol; Diabetes Mellitus; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Glucagon; Glycosuria; Hyperinsulinism; Hypertrophy; Immunohistochemistry; Inbreeding; Insulin; Islets of Langerhans; Male; Mice; Mice, Inbred Strains; Obesity; Pedigree; Pregnancy; Triglycerides | 1999 |
Adenylyl cyclase isoform expression in non-diabetic and diabetic Goto-Kakizaki (GK) rat pancreas. Evidence for distinct overexpression of type-8 adenylyl cyclase in diabetic GK rat islets.
Topics: Adenylyl Cyclases; Animals; Antibodies; Antibody Specificity; Diabetes Mellitus, Type 2; Disease Models, Animal; Endocrine Glands; Gene Expression Regulation; Glucagon; Immunohistochemistry; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Pancreas; Protein Isoforms; Rats; Rats, Inbred Strains; Rats, Wistar; Somatostatin | 2000 |
Deficiency of the intestinal growth factor, glucagon-like peptide 2, in the colon of SCID mice with inflammatory bowel disease induced by transplantation of CD4+ T cells.
Topics: Animals; CD4-Positive T-Lymphocytes; Colon; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Growth Substances; Inflammatory Bowel Diseases; Mice; Mice, SCID; Peptide Fragments | 2000 |
Alterations in glucose-6-phosphatase gene expression in sepsis.
Topics: Animals; Blotting, Northern; Corticosterone; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Glucagon; Glucose-6-Phosphatase; Insulin; Liver; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; RNA, Messenger; Shock, Septic; Time Factors | 2000 |
Impaired neural regulation of insulin secretion related to the leptin receptor gene mutation in Wistar fatty rats.
Topics: Animals; Atropine Derivatives; Blood Glucose; Carrier Proteins; Crosses, Genetic; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Injections, Intraventricular; Insulin; Insulin Resistance; Insulin Secretion; Mutation; Obesity; Peptide Fragments; Protein Precursors; Rats; Rats, Inbred WKY; Rats, Zucker; Receptors, Cell Surface; Receptors, Leptin; Vagotomy; Vagus Nerve | 2000 |
Early changes in islet hormone secretion in the hamster pancreatic cancer model.
Topics: Adenocarcinoma; Amyloid; Animals; Carcinogens; Cricetinae; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Glucose Tolerance Test; Insulin; Insulin Resistance; Insulin Secretion; Islet Amyloid Polypeptide; Islets of Langerhans; Male; Mesocricetus; Nitrosamines; Pancreatic Juice; Pancreatic Neoplasms; Somatostatin | 2001 |
Diabetogenic role of insulin's counterregulatory hormones in the isletectomized, diabetic goby.
Topics: Ammonia; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Fishes; Glucagon; Hydrocortisone; Hyperglycemia; Insulin; Islets of Langerhans; Kinetics; Nitrogen; Rats | 2000 |
Defective stimulus-secretion coupling in islets of Psammomys obesus, an animal model for type 2 diabetes.
Topics: Animals; Colforsin; Diabetes Mellitus, Type 2; Diazoxide; Disease Models, Animal; Disease Susceptibility; Gerbillinae; Glucagon; Glucagon-Like Peptide 1; Glucose; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Isoenzymes; Oxidation-Reduction; Peptide Fragments; Protein Kinase C; Protein Precursors; Rats; Rats, Sprague-Dawley; Reference Values; Signal Transduction; Tetradecanoylphorbol Acetate | 2001 |
Early development of beta-cells is impaired in the GK rat model of type 2 diabetes.
Topics: Animals; Apoptosis; Cell Differentiation; Cell Division; Culture Techniques; Diabetes Mellitus, Type 2; Disease Models, Animal; Embryonic and Fetal Development; Female; Fetus; Glucagon; Heart; Immunohistochemistry; Insulin; Islets of Langerhans; Kidney; Liver; Lung; Organ Size; Pregnancy; Rats; Rats, Wistar; Spleen | 2001 |
GLP-1 effect upon the GPI/IPG system in adipocytes and hepatocytes from diabetic rats.
Topics: Adipocytes; Animals; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 1; Glycosylphosphatidylinositols; Hepatocytes; Hypoglycemic Agents; Inositol Phosphates; Insulin; Liver; Male; Oligosaccharides; Pancreas; Peptide Fragments; Polysaccharides; Protein Precursors; Rats; Rats, Wistar | 2001 |
Insulin and glucagon secretions, and morphological change of pancreatic islets in OLETF rats, a model of type 2 diabetes mellitus.
Topics: Animals; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Insulin; Islets of Langerhans; Male; Rats; Rats, Inbred OLETF | 2002 |
Evaluation of glycated glucagon-like peptide-1(7-36)amide in intestinal tissue of normal and diabetic animal models.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycosylation; Hydrocortisone; Intestine, Small; Mice; Mice, Obese; Organ Size; Peptide Fragments; Rats | 2002 |
Functional and histochemical analysis on pancreatic islets of APA hamsters with SZ-induced hyperglycemia and hyperlipidemia.
Topics: Animals; Blood Glucose; Cricetinae; Disease Models, Animal; Glucagon; Glucose Tolerance Test; Hyperglycemia; Hyperlipidemias; Immunohistochemistry; In Situ Nick-End Labeling; Insulin; Islets of Langerhans; Male; Mesocricetus; Proliferating Cell Nuclear Antigen; Somatostatin; Streptozocin; Vacuoles | 2002 |
Stevioside induces antihyperglycaemic, insulinotropic and glucagonostatic effects in vivo: studies in the diabetic Goto-Kakizaki (GK) rats.
Topics: Animals; Area Under Curve; Diabetes Mellitus, Type 2; Disease Models, Animal; Diterpenes; Diterpenes, Kaurane; Glucagon; Glucose; Glucose Tolerance Test; Glucosides; Hyperglycemia; Hypoglycemic Agents; Injections, Intravenous; Insulin; Male; Phytotherapy; Plant Extracts; Rats; Rats, Inbred Strains; Rats, Wistar; Terpenes | 2002 |
Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat model by expansion of the beta-cell mass during the prediabetic period with glucagon-like peptide-1 or exendin-4.
Topics: Age Factors; Animals; Animals, Newborn; Blood Glucose; Body Weight; Cell Division; Diabetes Mellitus, Type 2; Disease Models, Animal; Exenatide; Female; Glucagon; Glucagon-Like Peptide 1; Insulin; Insulin Secretion; Islets of Langerhans; Longitudinal Studies; Peptide Fragments; Peptides; Protein Precursors; Rats; Rats, Mutant Strains; Rats, Wistar; Venoms | 2002 |
Mild streptozotocin diabetes in the Göttingen minipig. A novel model of moderate insulin deficiency and diabetes.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Fasting; Food; Glucagon; Glucose Tolerance Test; Insulin; Insulin Secretion; Islets of Langerhans; Male; Niacinamide; Streptozocin; Swine, Miniature; Time Factors | 2002 |
A hundred years of the hepatotrophic controversy.
Topics: Animals; Cell Division; Cyclic AMP; Diabetes Mellitus, Experimental; Disease Models, Animal; Dogs; Glucagon; Hepatic Artery; Insulin; Liver; Liver Circulation; Liver Regeneration; Pancreatectomy; Portacaval Shunt, Surgical; Portal Vein | 1977 |
The effects of common bile duct ligation upon the rat liver beta-adrenergic receptor-adenylate cylase system.
Topics: Adenylyl Cyclases; Animals; Bile Ducts; Cell Membrane; Cholestasis; Dihydroalprenolol; Disease Models, Animal; Enzyme Activation; Female; Glucagon; Isoproterenol; Kinetics; Liver; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1979 |
Glucagon treatment of hemorrhagic shock: improved survival and metabolic parameters in a murine shock model.
Topics: Animals; Disease Models, Animal; Female; Glucagon; Glucose; Glycogen; Liver; Male; Muscles; Rats; Shock, Hemorrhagic; Time Factors | 1978 |
The spontaneously diabetic Wistar rat. Metabolic and morphologic studies.
Topics: Aging; Amino Acids; Animals; Blood Glucose; Body Weight; Diabetes Mellitus; Disease Models, Animal; Female; Glucagon; Insulin; Islets of Langerhans; Male; Rats | 1977 |
Glucagon and insulin binding to liver membranes in a partially nephrectomized uremic rat model.
Topics: Adenylyl Cyclases; Animals; Blood Urea Nitrogen; Cell Membrane; Creatinine; Disease Models, Animal; Glucagon; Glucose; Hyperglycemia; Hyperinsulinism; Hypersensitivity; Insulin; Insulin Resistance; Kidney; Liver; Nephrectomy; Protein Binding; Rats; Uremia | 1977 |
Alteration of islet cell populations in spontaneously diabetic mice.
Topics: Animals; Diabetes Mellitus; Disease Models, Animal; Fluorescent Antibody Technique; Glucagon; Insulin; Islets of Langerhans; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Peptides; Somatostatin | 1978 |
Fine structural studies of the islets of langerhans in the Djungarian hamster (Phodopus sungorus).
Topics: Animals; Cell Differentiation; Cricetinae; Diabetes Mellitus; Disease Models, Animal; Glucagon; Islets of Langerhans; Keto Acids; Somatostatin | 1978 |
Physiologic aspects of intrasplenic autotransplantation of pancreatic fragments in the dog after 24 hours of cold storage.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Dogs; Female; Glucagon; Insulin; Islets of Langerhans Transplantation; Male; Pancreatectomy; Spleen; Time Factors; Tissue Preservation; Transplantation, Autologous | 1978 |
Effect of continuous low-dose insulin treatment on subsequent incidence of diabetes in genetically prediabetic Chinese hamsters.
Topics: Animals; Cricetinae; Cricetulus; Diabetes Mellitus; Disease Models, Animal; Female; Glucagon; Glucose Tolerance Test; Insulin; Insulin Antibodies; Male; Prediabetic State | 1979 |
Glucose production by the perfused liver of the spiny mouse (Acomys cahirinus): sensitivity to glucagon and insulin.
Topics: Animals; Body Weight; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glucagon; Glucose; Insulin; Lipids; Liver; Male; Mice | 1979 |
A controlled trial of glucagon in acute experimental pancreatitis in rats.
Topics: Acute Disease; Amylases; Animals; Disease Models, Animal; Glucagon; Ligation; Male; Pancreatitis; Rats; Taurocholic Acid | 1977 |
Glucagon, insulin, and glucose relationships in a porcine experimental burn model.
Topics: Amino Acids; Animals; Arginine; Blood Glucose; Burns; Disease Models, Animal; Fatty Acids, Nonesterified; Glucagon; Humans; Insulin; Insulin Secretion; Ketones; Resuscitation; Sodium Chloride; Splenectomy; Swine | 1978 |
Reduced triglyceride secretion: a metabolic consequence of chronic exercise.
Topics: Animals; Body Weight; Disease Models, Animal; Female; Glucagon; Hyperlipidemias; Insulin; Lipid Metabolism; Liver; Obesity; Physical Exertion; Rats; Rats, Inbred Strains; Thinness; Triglycerides | 1978 |
Effect of glucagon and blood transfusion on liver metabolism in hemorrhagic shock.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Blood Transfusion; Cell Membrane; Disease Models, Animal; Glucagon; Glucose; Glucosephosphates; Lactates; Liver; Male; Phosphocreatine; Potassium; Rats; Shock, Hemorrhagic; Sodium | 1978 |
Biochemical changes in a porcine model of acute pancreatitis.
Topics: Animals; Bile Acids and Salts; Blood Chemical Analysis; Disease Models, Animal; Glucagon; Hematocrit; Pancreatitis; Swine; Trypsin | 1978 |
Hyperglucagonemia and hepatic ketogenesis in burned swine.
Topics: Animals; Blood Glucose; Burns; Disease Models, Animal; Fatty Acids, Nonesterified; Glucagon; Heparin; Insulin; Ketones; Liver; Muscles; Swine | 1978 |
Hyperlipoproteinemia in experimental chronic renal insufficiency in the rat.
Topics: Animals; Blood Glucose; Disease Models, Animal; Glucagon; Hyperlipidemias; Insulin; Kidney Failure, Chronic; Lipids; Lipoproteins; Male; Nephrectomy; Rats | 1978 |
Renal effects of glucagon in dogs with hemorrhagic hypotension.
Topics: Animals; Blood Pressure; Disease Models, Animal; Dogs; Female; Glomerular Filtration Rate; Glucagon; Hemorrhage; Hypotension; Kidney; Male; Vascular Resistance | 1978 |
Glucagon, ureteral colic and ureteral peristalsis.
Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Dogs; Edema; Glucagon; Humans; In Vitro Techniques; Pain; Ureter; Ureteral Calculi; Ureteral Diseases; Ureteral Obstruction | 1978 |
Synergistic interactions of physiologic increments of glucagon, epinephrine, and cortisol in the dog: a model for stress-induced hyperglycemia.
Topics: Animals; Blood Glucose; Disease Models, Animal; Dogs; Drug Synergism; Epinephrine; Glucagon; Hydrocortisone; Hyperglycemia; Male; Stress, Physiological | 1979 |
The mechanism of hypoglycemia due to semistarvation in the rat.
Topics: Alanine; Animals; Blood Glucose; Disease Models, Animal; Energy Metabolism; Glucagon; Glucose; Glycerol; Hypoglycemia; Lipid Metabolism; Male; Protein-Energy Malnutrition; Rats | 1976 |
Effect of burn injury on glucose turnover in guinea pigs.
Topics: Animals; Blood Pressure; Burns; Cardiac Output; Corticosterone; Disease Models, Animal; Glucagon; Glucose; Guinea Pigs; Insulin; Male; Metabolic Clearance Rate; Oxygen Consumption | 1977 |
Studies with an artificial endocrine pancreas.
Topics: Animals; Artificial Organs; Blood Glucose; Diabetes Mellitus; Disease Models, Animal; Dogs; Fatty Acids, Nonesterified; Glucagon; Glucose Tolerance Test; Homeostasis; Humans; Insulin; Pancreas; Physical Exertion | 1977 |
[Modification of the oxygen supply of the small intestine demonstrated on the ileus model].
Topics: Animals; Disease Models, Animal; Glucagon; Intestinal Obstruction; Oxygen; Oxygen Consumption; Partial Pressure; Plasma Substitutes; Rabbits | 1976 |
Pathogenesis and characterization of hyperglucagonemia in the uremic rat.
Topics: Animals; Antigens; Disease Models, Animal; Glucagon; Kidney; Kidney Diseases; Male; Nephrectomy; Rats; Uremia | 1976 |
Effect of insulin and glucagon on fulminant murine hepatitis.
Topics: Acute Disease; Animals; Disease Models, Animal; Drug Synergism; Female; Glucagon; Hepatitis A; Insulin; Liver Regeneration; Mice; Time Factors | 1976 |
Prevention by glucagon of experimental stress induced hemorrhagic gastritis.
Topics: Animals; Disease Models, Animal; Gastric Juice; Gastritis; Gastrointestinal Hemorrhage; Glucagon; Male; Rats | 1975 |
The effect of increased pulmonary blood flow on the pulmonary vascular bed in pigs.
Topics: Animals; Arteriovenous Shunt, Surgical; Blood Pressure; Capillary Resistance; Cardiac Output; Cattle; Disease Models, Animal; Glucagon; Hypertension, Pulmonary; Hypoxia; Microcirculation; Pneumonectomy; Pulmonary Artery; Pulmonary Circulation; Swine | 1975 |
Altered insulin and glucagon secretion in treated genetic hyperlipemia: a mechanism of theraphy?
Topics: Animals; Arginine; Blood Glucose; Disease Models, Animal; Glucagon; Glycolates; Halofenate; Hyperglycemia; Hyperlipidemias; Insulin; Rats; Rats, Inbred Strains | 1976 |
Endocrine cell populations in the pancreas of diabetic WBN/Kob rats.
Topics: Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Immunohistochemistry; Insulin; Islets of Langerhans; Male; Rats; Rats, Inbred Strains; Somatostatin | 1992 |
Glucagon, insulin and somatostatin secretion in response to sympathetic neural activation in streptozotocin-induced diabetic rats. A study with the isolated perfused rat pancreas in vitro.
Topics: Animals; Animals, Newborn; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Electric Stimulation; Glucagon; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Neurons; Perfusion; Rats; Rats, Wistar; Somatostatin; Splanchnic Nerves; Streptozocin; Sympathetic Nervous System | 1992 |
Alterations in G-protein expression, Gi function and stimulatory receptor-mediated regulation of adipocyte adenylyl cyclase in a model of insulin-resistant diabetes with obesity.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Cells, Cultured; Colforsin; Diabetes Mellitus; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; GTP-Binding Proteins; Isoproterenol; Magnesium; Mice; Mice, Inbred CBA; Obesity; Secretin | 1992 |
Markedly reduced beta-cell function does not result in insulin resistance in islet autografted dogs.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Dogs; Female; Glucagon; Insulin; Insulin Resistance; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Pancreatectomy; Transplantation, Autologous | 1992 |
Changes in plasma insulin and glucagon concentrations and hepatic enzyme activities in diabetic voles treated with monosodium aspartate.
Topics: Animals; Arvicolinae; Aspartic Acid; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Fructose-Bisphosphatase; Glucagon; Glucokinase; Insulin; Liver | 1991 |
Repetitive exposure of pancreatic islets to interleukin-1 beta. An in vitro model of pre-diabetes?
Topics: Animals; Animals, Newborn; Cells, Cultured; Diabetes Mellitus, Type 1; Disease Models, Animal; DNA; Glucagon; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Rats; Rats, Inbred Strains; Recombinant Proteins | 1991 |
[Apollinaire Bouchardat 1991 Award. Insulin resistance in an animal model of hypoinsulinism].
Topics: Animals; Blood Glucose; Disease Models, Animal; Female; Glucagon; Gluconeogenesis; Insulin; Insulin Resistance; Lactation; Metabolic Diseases; Rats | 1991 |
Prevention of diabetes mellitus in BB rats by neonatal stimulation of beta cells.
Topics: Animals; Animals, Newborn; Arginine; Blood Glucose; Diabetes Mellitus, Type 1; Disease Models, Animal; Glucagon; Glucose; Islets of Langerhans; Rats; Rats, Inbred BB; Time Factors | 1990 |
Pancreatic polypeptide and other pancreatic hormones in spontaneously diabetic BB/W rats.
Topics: Animals; Blood Glucose; Cholesterol; Chromatography, Gel; Diabetes Mellitus; Disease Models, Animal; Glucagon; Insulin; Lipoproteins, HDL; Pancreas; Pancreatic Polypeptide; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatostatin; Triglycerides | 1990 |
Metabolic regulation of renal gluconeogenesis in response to sepsis in the rat.
Topics: Animals; Disease Models, Animal; Fructose-Bisphosphatase; Glucagon; Gluconeogenesis; Glucose-6-Phosphatase; Insulin; Kidney; Kidney Tubules; Male; Nitrogen; Phosphoenolpyruvate Carboxykinase (GTP); Pyruvate Carboxylase; Rats; Rats, Inbred Strains; Sepsis | 1990 |
Glucoregulatory, hormonal, and metabolic responses to endotoxicosis or cecal ligation and puncture sepsis in the rat: a direct comparison.
Topics: Animals; Blood Glucose; Cecum; Disease Models, Animal; Glucagon; Insulin; Kinetics; Lactates; Lactic Acid; Ligation; Male; Peritonitis; Punctures; Rats; Rats, Inbred Strains; Sepsis; Shock, Septic | 1990 |
Decreased insulin- and glucagon-pulse amplitude accompanying beta-cell deficiency induced by streptozocin in baboons.
Topics: Animals; Blood Glucose; Disease Models, Animal; Glucagon; Insulin; Insulin Secretion; Islets of Langerhans; Male; Papio; Streptozocin; Time Factors | 1989 |
The cause of death in non-metastasizing sarcoma-bearing mice. A study with relevance for tumor treatment experiments in mice.
Topics: Adrenalectomy; Animals; Dietary Carbohydrates; Disease Models, Animal; Female; Glucagon; Glucose; Hydrocortisone; Hypoglycemia; Male; Mice; Mice, Inbred C57BL; Sarcoma, Experimental | 1989 |
Effect of adrenalectomy on the pancreas of db/db mice.
Topics: Adrenalectomy; Animals; Body Weight; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Histocytochemistry; Immunologic Techniques; Insulin; Islets of Langerhans; Mice; Mice, Inbred C57BL; Somatostatin | 1986 |
Hypersecretion of gastric somatostatin in spontaneously diabetic BB rats.
Topics: Animals; Chromatography, Gel; Diabetes Mellitus; Disease Models, Animal; Gastric Mucosa; Glucagon; Insulin; Male; Perfusion; Portal Vein; Rats; Rats, Inbred Strains; Somatostatin | 1987 |
Spontaneous diabetes in Macaca nigra: relevance to human beings with NIDDM.
Topics: Animals; Autoantibodies; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Insulin; Islets of Langerhans; Macaca; Prediabetic State; Reference Values | 1988 |
Reduction of glycogen stores in a rat model of chronic hyperinsulinism.
Topics: Adrenal Glands; Animals; Blood Glucose; Chronic Disease; Disease Models, Animal; Glucagon; Glycogen; Hyperinsulinism; Insulin; Insulin Resistance; Liver; Male; Muscles; Organ Size; Rats; Rats, Inbred Strains | 1987 |
Beta-adrenergic blockade increases the hepatic extraction of glucose in sepsis.
Topics: Animals; Blood Glucose; Cholecystitis; Disease Models, Animal; Dogs; Epinephrine; Female; Gangrene; Glucagon; Glucose; Hemodynamics; Infections; Insulin; Liver; Liver Circulation; Male; Propranolol; Time Factors | 1986 |
Effects of hyperinsulinemia in the primate fetus.
Topics: Adipose Tissue; Amino Acids; Animals; Birth Weight; Blood Glucose; C-Peptide; Disease Models, Animal; Erythropoietin; Female; Fetal Blood; Fetal Hypoxia; Fetus; Glucagon; Hydrocortisone; Insulin; Macaca mulatta; Pregnancy; Pregnancy in Diabetics | 1985 |
Inhibition of bile flow by intravenous arginine hydrochloride.
Topics: Animals; Arginine; Bile; Bile Acids and Salts; Biliary Fistula; Blood Glucose; Cholestasis; Cholesterol; Chronic Disease; Disease Models, Animal; Dogs; Female; Glucagon; Infusions, Parenteral; Phospholipids | 1985 |
Dissociation between the chronotropic and inotropic actions of glucagon.
Topics: Animals; Disease Models, Animal; Dogs; Female; Glucagon; Heart Rate; In Vitro Techniques; Male; Pentobarbital; Piperidines; Plants, Medicinal; Plants, Toxic; Polycyclic Compounds; Stimulation, Chemical; Veratrum | 1974 |
Decreased glucagon activity: A mechanism for genetic and acquired endogenous hyperlipaemia.
Topics: Animals; Chlorides; Cobalt; Contraceptives, Oral; Diet; Dietary Carbohydrates; Disease Models, Animal; Fatty Acids; Fatty Acids, Nonesterified; Female; Glucagon; Humans; Hyperlipidemias; Lipid Metabolism, Inborn Errors; Lipoproteins; Liver; Obesity; Rats | 1974 |
The diabetic Chinese hamster: in vitro insulin and glucagon release; the ""chemical diabetic";; and the effect of diet on ketonuria.
Topics: Animals; Arginine; Cricetinae; Diabetes Mellitus; Diabetic Ketoacidosis; Disease Models, Animal; Female; Glucagon; Glucose; Glucose Tolerance Test; Glycosuria; Immunoassay; Insulin; Insulin Secretion; Male; Pancreas; Theophylline | 1974 |
Diabetogenic effect of streptozotocin in the rat during the perinatal period.
Topics: Animals; Animals, Newborn; Antigens; Blood Glucose; Diabetes Mellitus; Disease Models, Animal; Female; Fetus; Gestational Age; Glucagon; Glucose; Insulin; Iodine Radioisotopes; Liver Glycogen; Male; Pancreas; Pregnancy; Radioimmunoassay; Rats; Streptozocin; Swine; Time Factors | 1974 |
Proinsulin-like component of circulating insulin in the basal state and in patients and hamsters with islet cell tumors.
Topics: Acromegaly; Adenoma, Islet Cell; Adolescent; Adult; Animals; Child; Chromatography, Gel; Cricetinae; Cushing Syndrome; Diazoxide; Disease Models, Animal; Female; Glucagon; Glucose Tolerance Test; Half-Life; Humans; Hypoglycemia; Hypokalemia; Insulin; Iodine Isotopes; Leucine; Male; Middle Aged; Myotonic Dystrophy; Neoplasms, Experimental; Obesity; Proinsulin; Radioimmunoassay; Stimulation, Chemical; Tolbutamide | 1971 |
Adenosine 3',5'-monophosphate metabolism in the liver in experimental hemorrhagic shock.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cyclic AMP; Disease Models, Animal; Fluorides; Glucagon; Liver; Rabbits; Shock, Hemorrhagic; Sodium | 1973 |
Control of insulin secretion in the Egyptian sand rat ((Psammomys obesus).
Topics: Animals; Blood Glucose; Bucladesine; Disease Models, Animal; Epididymis; Female; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Male; Pancreas; Rats; Rats, Inbred Strains; Secretory Rate; Tolbutamide | 1974 |
Alpha-adrenergic inhibition of immunoreactive insulin release during deep hypothermia.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Glucose; Blood Pressure; Body Temperature; Diazoxide; Disease Models, Animal; Dogs; Glucagon; Glucose; Heart Rate; Hydralazine; Hypothermia; Immunoassay; Insulin; Phentolamine; Propranolol; Sympathetic Nervous System | 1971 |
Paradoxical glucagon release in obese hyperglycemic mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Disease Models, Animal; Glucagon; Hyperglycemia; Mice; Mice, Inbred Strains; Mutation; Obesity; Pancreas; Perfusion; Time | 1974 |
Metabolism of genetically obese rates on normal or high-fat diet.
Topics: Adipose Tissue; Animals; Blood Glucose; Dietary Fats; Disease Models, Animal; Epididymis; Fatty Acids; Glucagon; Glucose; Glycogen; In Vitro Techniques; Insulin; Lipids; Liver; Male; Muscles; Obesity; Pancreas; Phospholipids; Rats; Rats, Inbred Strains; Triglycerides | 1974 |
Experimental pancreatitis treated with glucagon or lactated Ringer solution.
Topics: Acute Disease; Animals; Bile; Disease Models, Animal; Dogs; Duodenal Obstruction; Edema; Female; Gastrointestinal Hemorrhage; Glucagon; Infusions, Parenteral; Injections, Intravenous; Lactates; Male; Pancreatic Ducts; Pancreatitis; Solutions; Trypsin | 1974 |
Glucose tolerance and insulin secretion in rabbits and dogs after ligation of the pancreatic ducts.
Topics: Administration, Oral; Animals; Blood Glucose; Disease Models, Animal; Dogs; Fasting; Glucagon; Glucose; Glucose Tolerance Test; Injections, Intravenous; Insulin; Insulin Secretion; Islets of Langerhans; Ligation; Pancreatic Ducts; Postoperative Complications; Rabbits; Rats | 1974 |
Studies of immunoreactive insulin secretion in NZO mice in vivo.
Topics: Aminophylline; Animals; Antigens; Arginine; Diabetes Mellitus; Disease Models, Animal; Fasting; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isoproterenol; Mice; Mice, Inbred Strains; Obesity; Phenytoin; Radioimmunoassay; Secretory Rate | 1974 |
Effects of isoproterenol, l-norepinephrine, and glucagon on myocardial gas tensions in animals with coronary artery stenosis.
Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Disease Models, Animal; Dogs; Glucagon; Heart Rate; Isoproterenol; Mass Spectrometry; Myocardium; Norepinephrine; Oxygen; Oxygen Consumption; Partial Pressure | 1973 |
Abnormal secretion of insulin and glucagon by the in vitro perfused pancreas of the genetically diabetic Chinese hamster.
Topics: Animals; Blood Glucose; Cattle; Cricetinae; Diabetes Mellitus; Disease Models, Animal; Drug Combinations; Female; Glucagon; Glucose; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Male; Pancreas; Perfusion; Rats; Swine; Theophylline | 1974 |
Proceedings: Acute pancreatitis in the pig--development of a model and a controlled trial of glucagon treatment.
Topics: Acute Disease; Animals; Disease Models, Animal; Glucagon; Pancreatitis; Swine | 1974 |
Model of human coronary artery disease for acute experimentation.
Topics: Animals; Arteries; Blood Flow Velocity; Blood Pressure; Cardiac Output; Coronary Circulation; Coronary Disease; Coronary Vessels; Depression, Chemical; Disease Models, Animal; Dogs; Electrocardiography; Glucagon; Heart; Heart Ventricles; Ischemia; Isoproterenol; Lactates; Ligation; Myocardium; Time Factors | 1974 |
Ultrastructural changes in A-cells exposed to diabetic hyperglycaemia. Observations made on pancreas of Chinese hamsters.
Topics: Acidosis; Animals; Blood Glucose; Cell Nucleus; Cricetinae; Cytoplasmic Granules; Diabetes Mellitus; Disease Models, Animal; Endoplasmic Reticulum; Glucagon; Glycogen; Golgi Apparatus; Insulin; Islets of Langerhans; Lysosomes; Male; Microscopy, Electron | 1970 |
Pathogenetic aspects of the obese-hyperglycemic syndrome in mice (genotype obob). I. Function of the pancreatic B-cells.
Topics: Age Factors; Animals; Blood Glucose; Body Weight; Disease Models, Animal; Glucagon; Glucose Tolerance Test; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Obesity | 1970 |
Control of alloxan diabetes in dogs by islet cell transplantation.
Topics: Animals; Atrophy; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Dogs; Glucagon; Islets of Langerhans Transplantation; Pancreas; Pancreatectomy; Tolbutamide; Transplantation, Homologous | 1971 |
Experimental myocardial infarction. X. Efficacy of glucagon in acute and healing phase in intact conscious dogs: effects on hemodynamics and myocardial oxygen consumption.
Topics: Acute Disease; Animals; Blood Pressure; Cardiac Output; Coronary Circulation; Disease Models, Animal; Dogs; Glucagon; Heart Rate; Myocardial Infarction; Myocardium; Oxygen Consumption; Stimulation, Chemical; Vascular Resistance | 1972 |
Influence of glucagon on the ischemic liver in the pig.
Topics: Animals; Aspartate Aminotransferases; Disease Models, Animal; Galactosidases; Glucagon; Glucosidases; Hepatic Artery; Hydrolases; Ischemia; L-Lactate Dehydrogenase; Liver; Liver Circulation; Liver Glycogen; Stimulation, Chemical; Swine | 1972 |
Failure of glucagon in experimental hemorrhagic shock.
Topics: Animals; Arteries; Blood Pressure; Cardiac Output; Disease Models, Animal; Dogs; Evaluation Studies as Topic; Female; Glucagon; Heart Rate; Hemodynamics; Male; Shock, Hemorrhagic; Vascular Resistance | 1971 |
The control of postnatal hypoglycemia. Suggestions based on experimental observations in neonatal rats.
Topics: Animals; Animals, Newborn; Blood Glucose; Dactinomycin; Depression, Chemical; Disease Models, Animal; Enzyme Induction; Glucagon; Gluconeogenesis; Glucose; Hypoglycemia; Liver; Liver Glycogen; Phosphoenolpyruvate Carboxykinase (GTP); Phosphorylases; Rats | 1971 |
The effects of feeding and various hormones on the glucose tolerance of the sand rat (Psammomys obesus).
Topics: Animals; Cortisone; Diabetes Mellitus; Diet; Disease Models, Animal; Food Deprivation; Glucagon; Glucose; Glucose Tolerance Test; Growth Hormone; Hormones; Insulin; Phenformin; Rats | 1967 |
Glucagonlike peptide-2 analogue: a possible new approach in the management of inflammatory bowel disease.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Defecation; Diarrhea; Disease Models, Animal; Female; Glucagon-Like Peptides; HLA-B27 Antigen; Ileum; Inflammatory Bowel Diseases; Injections, Intravenous; Intestinal Mucosa; Peptides; Rats; Rats, Inbred F344; Rats, Mutant Strains | 2004 |
Preserved GLP-I effects on glycogen synthase a activity and glucose metabolism in isolated hepatocytes and skeletal muscle from diabetic rats.
Topics: Animals; Animals, Newborn; Carbon Radioisotopes; Cells, Cultured; Cohort Studies; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon-Like Peptides; Glucose; Glycogen Synthase; Insulin; Liver; Muscle, Skeletal; Pancreatic Hormones; Peptides; Phosphorylases; Rats; Rats, Wistar | 1997 |
Glucagonlike peptide-2 analogue enhances intestinal mucosal mass and absorptive function after ischemia-reperfusion injury.
Topics: Animals; Disease Models, Animal; DNA; Galactose; Glucagon-Like Peptides; Glycine; Infusions, Intravenous; Intestinal Absorption; Intestinal Mucosa; Male; Peptides; Probability; Rats; Rats, Sprague-Dawley; Reference Values; Reperfusion Injury | 2000 |
GLP-2alpha accelerates recovery of mucosal absorptive function after intestinal ischemia/reperfusion.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Galactose; Glucagon-Like Peptides; Glycine; Infusions, Intravenous; Intestinal Absorption; Intestinal Mucosa; Ischemia; Male; Peptides; Probability; Rats; Rats, Sprague-Dawley; Reference Values; Reperfusion; Treatment Outcome | 2001 |