glucagon has been researched along with Autoimmune Diabetes in 1293 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 394 (30.47) | 18.7374 |
| 1990's | 320 (24.75) | 18.2507 |
| 2000's | 186 (14.39) | 29.6817 |
| 2010's | 287 (22.20) | 24.3611 |
| 2020's | 106 (8.20) | 2.80 |
| Authors | Studies |
|---|---|
| Angarita, L; Bermúdez, V; Cabrera de Bravo, M; Cano, C; Chacín, M; D'Marco, L; Guerrero-Wyss, M; Manzano, A; Martínez, MS; Nava, M; Olivar, LC; Ortiz, R; Salazar, J | 1 |
| La Sala, L; Pontiroli, AE | 1 |
| Fougner, AL; Lopez-Zazueta, C; Stavdahl, O | 1 |
| Boeder, SC; Giovannetti, ER; Gregory, JM; Pettus, JH | 1 |
| Caicedo, A; Panzer, JK | 1 |
| Aiken, J; Appadurai, D; Chan, O; D'Souza, NC; Farhat, R; Hull, G; Liggins, RT; Riddell, MC; Simonson, E | 1 |
| Bispham, J; Chapman, K; Hughes, AS; Leon, C; Nguyen, H; Wolf, WA | 1 |
| Algeffari, M; Alghadouni, H; Almogbel, T; Alsharidah, M; Hussain, S; Mahmood, F | 1 |
| Laffel, LM; Sperling, MA | 1 |
| Aronson, R; Bode, B; Christiansen, MP; Conoscenti, V; Junaidi, K; Pieber, TR | 1 |
| Boulgaropoulos, B; Brunner, M; Haberlander, M; Moser, O; Obermayer-Pietsch, B; Pieber, TR; Raml, R; Sourij, H; Svehlikova, E | 1 |
| Aiello, E; Brusco, N; Dotta, F; Fignani, D; Formichi, C; Grieco, GE; Jorgensen, KD; Krogvold, L; Licata, G; Marchetti, P; Marselli, L; Nigi, L; Sebastiani, G | 1 |
| Dolan, EB; Domingo-Lopez, DA; Duffy, GP; H J Schreiber, L; Lattanzi, G; O'Sullivan, J; Wallace, EJ; Wylie, R | 1 |
| Åm, MK; Carlsen, SM; Christiansen, SC; Teigen, IA | 1 |
| Born, J; Dembinski, K; Hallschmid, M; Lehnert, H; Meyhöfer, S; Meyhöfer, SM; Schultes, B; Wilms, B | 1 |
| Laugesen, C; Nørgaard, K; Ranjan, AG; Schmidt, S | 1 |
| Buckingham, B; Conoscenti, V; Prestrelski, SJ; Sherr, J | 1 |
| Åm, MK; Berge, MH; Carlsen, SM; Christiansen, SC; Munkerud, EY | 1 |
| Chen, M; Fang, L; Lan, M; Lin, L; Ou, K; Song, J; Wang, C; Zhang, S | 1 |
| Atkinson, MA; Brissova, M; Doliba, NM; Gao, L; Golson, ML; Kaestner, KH; Liu, C; Liu, J; Manduchi, E; Matschinsky, FM; Naji, A; Powers, AC; Qin, W; Roman, J; Rozo, AV; Stoffers, DA; Traum, D; Vahedi, G | 1 |
| Chen, A; DePaoli, A; Fanget, M; Fox, M; Guo, W; Haldankar, R; Humphrey, M; Kaplan, DD; Kekatpure, A; Kutach, A; Li, D; Lindhout, DA; Liu, W; Liu, Z; Matern, H; Mondal, K; Ngan, I; Pedersen, O; Shen, D; Solloway, MJ; Song, B; Tang, J; Tian, H; Wang, Y; Winans, B; Wu, H; Xi, Y; Yang, H; Younis, H; Zha, J; Zhou, M | 1 |
| De Battista, H; Fushimi, E; Garelli, F | 1 |
| Heaton, ES; Jin, S | 1 |
| Ju, Y; Yang, J; Zhang, D | 1 |
| Asadi, F; Chung, YH; Kong, C; Ng, XW; Piston, DW; Ustione, A | 1 |
| Story, LH; Wilson, LM | 1 |
| Della Corte, F; Manzo, A; Monzani, A; Pozzi, E; Rabbone, I; Sainaghi, PP; Savastio, S; Scalogna, A | 1 |
| Besselink, MG; Blauw, H; Bonsing, BA; Bruno, MJ; Busch, OR; DeVries, JH; Klaassen, M; Latenstein, AEJ; Lips, DJ; Stommel, MWJ; van der Harst, E; van Dieren, S; van Eijck, CHJ; van Santvoort, HC; van Veldhuisen, CL; Vlaskamp, LB | 1 |
| Lebrethon, MC; Philips, JC; Radermecker, RP; S, S | 1 |
| Cui, X; Gu, L; Hong, T; Lin, X; Wei, R; Yang, J; Yang, K | 1 |
| Bain, SC; Bracken, R; Christensen, MB; McCarthy, O; Nørgaard, K; Schmidt, S | 1 |
| Hosoe, S; Ishizaka, Y; Kageyama, Y; Katakami, N; Kawamori, D; Shimomura, I; Tanaka, T | 1 |
| Akturk, HK; Bailey, TS; Bautista, ED; Bode, BW; Boeder, SC; Cheng, MHM; Christiansen, MP; Denham, DS; Garg, SK; Klaff, LJ; Klein, S; Pettus, J; Rosenstock, J; Thai, D; Xu, R; Yan, H | 1 |
| Sherr, J; Van Name, M | 1 |
| Dholariya, S; Dutta, S; Parchwani, D; Singh, R | 1 |
| Brawerman, G; Ntranos, V; Thompson, PJ | 1 |
| Cheng, L; Gu, Z; Hou, W; Liu, W; Sheng, T; Wang, H; Wang, S; Yang, C; Yu, J; Yu, X; Zhang, J; Zhang, Y | 1 |
| Caicedo, A; Panzer, JK; Tamayo, A | 1 |
| Rąpała, M; Stefanowicz-Bielska, A; Słomion, M | 1 |
| Choat, HM; Lunsford, AA; Martin, A; McCormick, KL; McGwin, GG; Mick, GJ; Tse, HM | 1 |
| Baillie, N; Baxter, F; Forbes, S | 1 |
| Galindo, RJ; Heien, HC; Herges, JR; McCoy, RG; Neumiller, JJ; Umpierrez, GE | 1 |
| Aronson, R; Conoscenti, V; Junaidi, MK; Riddell, MC | 1 |
| Aronson, R; Bailey, TS; Battelino, T; Danne, T; DiMeglio, LA; Heller, S; Hövelmann, U; Johansen, T; Melgaard, AE; Pieber, TR; Plum-Mörschel, L | 1 |
| Aramandla, R; Bottino, R; Bradley, AM; Brissova, M; Caicedo, A; Cartailler, JP; Haliyur, R; Jenkins, R; Kang, H; Petronglo, J; Phillips, S; Powers, AC; Reinert, RB; Richardson, TM; Saunders, DC; Shrestha, S | 1 |
| Kaur, J; Seaquist, ER | 1 |
| Bondia, J; Díez, JL; Furió-Novejarque, C; Jørgensen, JB; Nørgaard, K; Ranjan, AG; Reenberg, AT; Ritschel, TKS; Sanz, R | 1 |
| Desai, U; Mitchell, BD; Pearson, TL; Stuckey, HL | 1 |
| Binns, DD; Cobb, MH; Evans, MR; Kalwat, MA; Posner, BA; Rodrigues-Dos-Santos, K; Roth, MG; Wei, S; Zhou, A | 1 |
| Arbabi, S; Cason, RL; Dai, Y; Lindquist, D; Patel, SB; Sheanon, N; Warner, SO; Winnick, JJ; Yao, MV | 1 |
| Dover, AR; Forbes, S; Gibb, FW; Jeeyavudeen, MS; Lyall, MJ; Stimson, RH; Strachan, MWJ; Wright, RJ | 1 |
| Barouti, AA; Björklund, A; Brismar, K; Catrina, SB; Rajamand Ekberg, N | 1 |
| Borg, DJ; Ewing, A; Forbes, JM; Gerling, I; Harris, M; Le Bagge, S; Lenchik, N; Leung, SS; Mathews, C; McCarthy, DA; Pugliese, A; Radford, KJ | 1 |
| Maiti, R; Maji, S; Mohanty, RR | 1 |
| Bernatchez, F; Boulet, G; Brazeau, AS; Chouinard-Castonguay, S; Gagnon, C; Henderson, M; Kinnard, N; Mégalli, M; Millette, M; Rabasa-Lhoret, R; Simoneau-Roy, J; Tremblay, MC; Vanasse, A; Wang, YP | 1 |
| De Vito, G; Krause, M | 1 |
| Bolli, GB; Candeloro, P; Cioli, P; Fanelli, CG; Lucidi, P; Marinelli Andreoli, A; Porcellati, F | 1 |
| Katakami, N; Kawamori, D; Matsuoka, TA; Miyashita, K; Shimomura, I; Takahara, M; Takebe, S; Yasuda, T | 1 |
| De Leon, DD; Hawkes, CP; Rickels, MR | 1 |
| Laugesen, C; Nørgaard, K; Ranjan, AG; Schmidt, S; Tetzschner, R | 1 |
| Brooks, A; Guyton, J; Jeon, M | 1 |
| Beebe, C; Fortmann, AL; Johnson, KE; Nguyen, A; Polonsky, WH | 1 |
| Rabbone, I; Tinti, D | 1 |
| Andersen, B; Bokhari, MH; Busby, O; Cannon, B; Conde-Frieboes, KW; Fels, JJ; Nedergaard, J; Paulsson, JF; Rakipovski, G; Raun, K; Zouhar, P | 1 |
| Okada, J; Okada, S; Yamada, E; Yamada, M | 1 |
| Castle, JR; Jacobs, PG; Wilson, LM | 1 |
| Pontiroli, AE; Tagliabue, E | 2 |
| Matsuhisa, M; Nagai, Y; Nagashima, H; Nasu, R; Ohwaki, K; Takita, Y | 1 |
| Hu, J; Hu, Y; Li, S; Tan, X; Wang, D; Wang, L; Zou, P | 1 |
| Armouche, S; Brouard, J; Dolladille, C; Tournilhac, C; Vial, S | 1 |
| Abbasnezhad, A; Abd El-Ghafar, OA; Abhilash, L; Abouzid, KAM; Achberger, AM; Ackerman, S; Akhatayeva, Z; Akin, D; Al-Kaysi, RO; Alakhdar, AA; Alame, M; Aleksic Sabo, V; Alinezhadbalalami, N; Allen, JD; Alonso, JM; Alqatani, S; Alsayed, B; Álvarez Larraondo, M; Alvarez, M; Amini, SB; An, Z; Anasir, MI; Anderson, GH; Andremont, A; Andrés, S; Angel, S; Anigboro, AA; Anini, Y; Antonides, CFJ; Arafa, K; Arafa, RK; Aryal, UK; Asbaghi, O; Assefa, MK; Atyah, M; Avwioroko, OJ; Ayora-Talavera, G; Azpilikueta, A; Azyazov, VN; Ba, YF; Bachmann, KF; Badoual, J; Bae, SJ; Baek, SH; Bahrami, B; Bai, J; Baid-Agrawal, S; Bailey, MR; Baillie, JK; Balani, N; Balcar, VJ; Banica, T; Banks, L; Barb, J; Bardeen, CJ; Barrett, HE; Bartnikowski, N; Bashir, R; Battaglia, M; Bautista-Hernández, V; Becker, B; Beekman, FJ; Benidir, M; Benjelloun, M; Bentley, RF; Bergé, J; Berger, D; Bernsen, MR; Berraondo, P; Bhattacharya, R; Bhayani, SB; Bi, W; Bi, X; Bi, YL; Bi, Z; Bian, K; Biesecker, LG; Billadeau, DD; Blaszczyk, R; Blum, JL; Boachie, R; Boelte, K; Bogers, AJJC; Boileau, I; Bonduelle, C; Bonny, O; Bonsu, JM; Boos, LA; Borges-Argáez, R; Bouchard, PA; Boudot, C; Bourgeade-Delmas, S; Boutet-Robinet, E; Boyle, AJ; Branigan, D; Briones, S; Broniowska, KA; Brossas, JY; Brown, WA; Brzezinska, J; Buitron, G; Burnier, M; Bursulaya, B; Burton, PR; Bush, AA; Busuttil, RW; Cabello-Aguilar, S; Cáceres-Farfán, M; Cacheux, V; Caffrey, PJ; Cai, B; Cai, Q; Cai, S; Cai, Y; Calders, P; Cammarota, G; Campbell, DA; Cancelli, C; Cao, Q; Cao, WH; Cao, X; Capet, M; Capoluongo, E; Carey, ME; Carnero, M; Carrasco, LI; Carreno, J; Carrillo-Reyes, J; Casini, I; Cassar, M; Catalan, G; Cattamanchi, A; Cazares-Granillo, M; Celie, B; Cen, YK; Cena, H; Cerbo, RM; Ceron, E; Cetina-Montejo, L; Chaâbane-Banaoues, R; Chabanet, C; Chace-Donahue, F; Chalfun-Júnior, A; Chan-Balan, R; Chang, CS; Chen, CS; Chen, D; Chen, J; Chen, L; Chen, PN; Chen, Q; Chen, S; Chen, W; Chen, WP; Chen, X; Chen, Z; Cheng, H; Cheng, J; Cheng, Q; Cheng, T; Chi, T; Chianelli, D; Chieppa, M; Child, CJ; Cho, JH; Cho, JY; Chogtu, B; Choi, GH; Choi, J; Choi, M; Choi, NG; Cholu, CO; Chow, ES; Chowdhury, AH; Chu, PC; Chu, Q; Chu, S; Chua, H; Chung, T; Chunyan, L; Church, JS; Civardi, E; Cobiella, J; Colinge, J; Collado, CJ; Collins, TJ; Cong, LM; Conkrite, KL; Cope, SJ; Corbett, JA; Cornet, M; Cornillot, E; Corvaisier, S; Costes-Martineau, V; Courtioux, B; Coussens, M; Covino, M; Criado, A; Cui, J; Cui, Y; Cunitz, BW; Curry, AE; Cussó, L; D'Urzo, AD; D'Urzo, KA; Dabbous, S; Dahlgren, RA; Dai, H; Dai, T; Dai, W; Dalinghaus, M; Dang, S; Davalos, RV; Davidson, H; de Andrea, CE; De Angelis, M; de Blois, E; de Carvalho, PA; De Clercq, E; De Giuseppe, R; de Jong, M; De Langhe, S; De Oliveira, L; de Souza Pinto Lemgruber, R; de Souza, LB; de Swart, J; De Wandele, I; de Woestijne, PCV; Delaney, S; Delorme, M; Delvenne, P; Deng, L; Deng, Z; Denkinger, CM; der Meulen, MHV; Deraeve, C; Desco, M; DeSilva, S; Destere, A; Dhali, A; Di Ciano, P; Dias-Santagata, D; Diskin, SJ; Djè, MK; Doddipatla, S; Doerr, AJ; Dokla, EME; Domiciano, D; Domingo, N; Dong, C; Dong, J; Dong, Q; Dong, S; Dong, X; Dong, Z; Douair, I; Douglas, TA; Doyle, SM; Drain, PK; Du, K; Du, L; Du, Q; Du, S; Duan, C; Duan, H; Duan, J; Duan, S; Duan, W; Dueluzeau, R; Dukic, L; Dunmire, BL; Duvauchelle, T; Dymek, B; Dzwonek, K; Earnest, A; Eckardt, KU; El Ghadraoui, L; El Massoudi, S; Elloumi, F; Elnour, IE; Embarak, S; Ende, M; England, K; Enikeev, D; Enyedy, I; Epple, R; Erickson, GE; Eriksson, J; Erndt-Marino, J; Errachidi, F; Etxeberria, I; Evan, AP; Fairlamb, AH; Falahi, E; Fan, CC; Fan, H; Fan, M; Fan, MZ; Fan, S; Fan, Y; Fang, CS; Fang, J; Fang, X; Fang, Z; Farmany, A; Farooqi, A; Farouk, HO; Fazelipour, S; Feng, D; Feng, J; Feng, JX; Feng, YL; Ferraz, SL; Ferreira, CR; Figenshau, RS; Finn, AV; Fiseha, T; Fleischer, AS; Fogleman, AD; Fontaine, O; Ford, CR; Fouladvand, F; Four, M; Fousteri, G; Francis, JR; Fraser, JF; Frazier, RP; Fu, H; Fu, P; Fu, YJ; Fujishima, A; Fuster, V; Gabilan, JC; Gagliani, N; Gai, QY; Galán-Arriola, C; Gale, P; Galimova, GR; Galkin, A; Gallo, A; Gallo, AA; Gang, DD; Ganschow, S; Gao, C; Gao, F; Gao, GP; Gao, H; Gao, K; Gao, M; Gao, MY; Gao, P; Gao, R; Gao, S; Gao, WJ; Gao, Y; Garbacz, P; García Ruiz, L; Garcia, EM; Garofoli, F; Gasbarrini, A; Gattinoni, L; Gaudig, M; Gbureck, U; Ge, X; Genko, N; Gentile, GL; George, MW; Gerety, GF; Gestwicki, JE; Geusens, PP; Ghassemi, M; Giardina, JD; Giebultowicz, JM; Gifford, CA; Gijsen, FJH; Gilfillan, R; Gilson, E; Gingl, K; Giuliano, C; Glybochko, P; Goessler, W; Gofflot, S; Golab, J; Goldstein, A; Golebiowski, A; Gómez, L; Gómez-Carballo, J; Gonçalves, PEO; Gonzales, R; Gonzalez-Cotto, M; González-Fernández, D; Gonzalez-Lopez de Turiso, F; Goodman, JM; Govinda Raju, S; Grimm, J; Gross, AJ; Gruenheid, S; Gu, C; Gu, FF; Gu, S; Gu, Z; Guest, RL; Gui, C; Gui, J; Guillem, A; Guo, G; Guo, L; Guo, Q; Guo, S; Guo, SW; Guo, W; Guo, Y; Guo, YG; Guo, Z; Guretzky, JA; Haenggi, M; Hahn, MS; Hakkola, J; Halim, AA; Hampel, D; Han, B; Han, BH; Han, D; Han, G; Han, J; Han, LZ; Han, R; Han, S; Han, X; Han, Z; Handley, MA; Hanke, I; Hannongbua, S; Hao, P; Happ, JT; Hara, M; Haraux, F; Hare, JL; Harper, JD; Hartley, AM; Harvey, E; Hashimoto, K; Hassan, HM; Hautajärvi, H; Hayton, TW; He, C; He, H; He, HJ; He, WP; He, Y; He, Z; Hedrick, V; Heffernan, JK; Hegrová, J; Heidarimoghadam, R; Helms, K; Hengphasatporn, K; Henry, D; Herrmann, TRW; Hesson, T; Himmelbauer, MK; Hindle, A; Hoffmann, R; Hogg, N; Hong, KB; Hong, SK; Honjol, Y; Hood, C; Hsi, RS; Hsu, JL; Hu, B; Hu, BC; Hu, D; Hu, H; Hu, J; Hu, K; Hu, M; Hu, MK; Hu, T; Hu, W; Hu, Y; Hu, Z; Hua, S; Huang, H; Huang, J; Huang, L; Huang, M; Huang, P; Huang, X; Huang, Y; Huang, Z; Hukkanen, J; Hung, MC; Huo, X; Hyötyläinen, T; Ianiro, G; Ibanez, B; Imran, M; Ireland, S; Irwin, MS; Ishiguro, H; Jackowski, K; Jackson, C; Jacob, SI; Jahromy, MH; Jakob, SM; Jang, J; Javvaji, PK; Jefferson, KK; Jena, P; Ji, H; Jiang, F; Jiang, GH; Jiang, H; Jiang, J; Jiang, X; Jiang, Z; Jiao, J; Jiménez, A; Jin, X; Jincai, W; Jintao, X; Jo, K; Jofra, T; Johari, Y; Johnson, ACM; Jones, JH; Josephine Fauci, A; Juhl, AK; Jun, S; Kaiser, RI; Kajioka, J; Kajiyama, H; Kalliyil, A; Kalthur, SG; Kamalanathan, M; Kamaldinov, T; Kanaani, L; Kang, D; Kang, J; Kang, S; Känsäkoski, P; Kaplan, DL; Karwan, M; Kasibhatla, S; Kaur, A; Kawazoe, Y; Ke, C; Keyser, J; Khalique, A; Khan, IT; Kharshoum, RM; Kher, R; Kherani, J; Ki, KK; Kikkawa, F; Kikkawa, R; Kim, BT; Kim, EH; Kim, GA; Kim, GD; Kim, HB; Kim, HG; Kim, JS; Kim, MJ; Kim, SI; Kim, SJ; Kim, Y; King, K; Kinyamu-Akunda, J; Kirkkala, T; Kjaer-Sorensen, K; Kleppinger, EL; Kloner, RA; Klopfenstein, TJ; Knappe, D; Knezevic, P; Kobos, LM; Kohli, M; Kolano, L; Kolodgie, FD; Kolte, AP; Koneru, B; Kong, D; Kong, F; Kong, X; Konggidinata, MI; Köpke, M; Koski, KG; Kotsis, F; Köttgen, A; Kouakou-Kouamé, CA; Kraemer, US; Krane, V; Krehbiel, CR; Krenning, BJ; Kretzschmar, D; Ku, KB; Kubota, Y; Kulich, P; Kumar, NG; Kupiec-Weglinski, JW; Lalani, SS; Lan, X; Landfeldt, E; Langenberg, E; Lapauw, B; Larkin, J; Lassoued, MA; Laukhtina, E; Laura Martinez, J; Laveillé, A; Lavela, P; Law, AD; Lazraq, A; Le Foll, B; Lee, BK; Lee, C; Lee, CS; Lee, EJ; Lee, EY; Lee, G; Lee, HY; Lee, JH; Lee, JJ; Lee, JO; Lee, JS; Lee, R; Lei, H; Lei, P; Lellouche, F; Lennerz, JK; Leong, W; Leslie, I; Lessem, E; Levin, M; Levinger, I; Li, C; Li, CW; Li, CX; Li, CY; Li, D; Li, H; Li, HM; Li, J; Li, L; Li, LM; Li, N; Li, S; Li, W; Li, X; Li, XX; Li, Y; Li, Z; Li, ZL; Li, ZX; Lian, Q; Liang, C; Liang, GH; Liang, H; Liang, J; Liang, X; Liao, CX; Liao, R; Ličbinský, R; Lim, YS; Lima, HK; Lin, JG; Lin, L; Lin, S; Lin, WP; Lin, Z; Liso, M; Liu, BX; Liu, C; Liu, H; Liu, J; Liu, M; Liu, Q; Liu, S; Liu, SF; Liu, SL; Liu, T; Liu, W; Liu, X; Liu, XB; Liu, Y; Liu, YY; Liu, Z; Liu, ZQ; Lobo, M; Loitzenbauer, M; López, F; Lopez, G; López, GJ; Lou, Z; Lu, IC; Lu, J; Lu, M; Lu, W; Lu, X; Lu, Y; Luhovyy, BL; Luna-Abanto, J; Luo, J; Luo, K; Luo, L; Luo, M; Luo, W; Luo, X; Luo, XM; Lv, Y; 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| Russell, SJ | 1 |
| Haidar, A; Legault, L; Leroux, C; Messier, V; Mitre, TM; Rabasa-Lhoret, R | 1 |
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| Holst, JJ; Madsbad, S; Nørgaard, K; Ranjan, A; Reiband, HK; Schmidt, S | 1 |
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| Chen, S; Evans, MR; Lee, Y; Philippe, J; Roth, MG; Shi, Z; Unger, RH; Wang, MY; Williams, A; Yan, H; Yu, X | 1 |
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| Campbell, MD; Gonzalez, JT; Rumbold, PL; Shaw, JA; Stevenson, EJ; Walker, M; West, DJ | 1 |
| Clausen, TD; Damm, P; Hansen, T; Holst, JJ; Kelstrup, L; Mathiesen, ER | 1 |
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| Coleman, MP; Cooper, E; Mundinger, TO; Taborsky, GJ | 1 |
| de Bruin, TW; Herrmann, K; Kolterman, OG; Öhman, P; Riddle, MC; Xu, J; Yuen, KC | 1 |
| Cox, AR; Hess, RS; Kushner, JA; Lam, CJ; Rankin, MM; Shields, EJ; Van Winkle, TJ | 1 |
| Dallaire, M; Haidar, A; Ladouceur, M; Legault, L; Matteau-Pelletier, L; Messier, V; Rabasa-Lhoret, R | 1 |
| Castle, JR | 1 |
| Allen, EJ; Brand, CL; Cherrington, AD; Donahue, EP; Edgerton, DS; Farmer, B; Fledelius, C; Gregory, JM; Hastings, JR; Kraft, G; Neal, DW; Nishimura, E; Rivera, N; Scott, MF; Smith, MS; Winnick, JJ | 1 |
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| Basu, A; Basu, R; Carter, RE; Cobelli, C; Dalla Man, C; Hinshaw, L; Kudva, YC; Mallad, A | 1 |
| Gala-Lopez, B; MacGillivary, A; Mazzuca, DM; Pawlick, R; Pepper, AR; Shapiro, AM; Toleikis, PM; White, DJ | 1 |
| Bakhtiani, PA; Branigan, D; Cai, Y; Castle, JR; El Youssef, J; Jacobs, P; Ramsey, K; Reddy, R; Stobbe, JM; Ward, WK; Woods, M | 1 |
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| Branigan, D; Castle, J; Condon, J; El Youssef, J; Jacobs, PG; Preiser, N; Reddy, R; Resalat, N | 1 |
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| Chen, H; Luo, N; Wang, Y; Zhang, Z; Zhu, Y | 1 |
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| Covey, SD; Denroche, HC; Kieffer, TJ; Mojibian, M; Neumann, UH | 1 |
| Davidson, JA; Holland, WL; Lee, Y; McCorkle, SK; Roth, MG; Scherer, PE; Unger, RH; Wang, MY; Yu, X | 1 |
| Holst, JJ; Madsbad, S; Nørgaard, K; Ranjan, A; Schmidt, S | 1 |
| Balliro, C; Damiano, ER; Ekhlaspour, L; El-Khatib, FH; Grennan, K; Hillard, MA; Magyar, KL; Mondesir, D; Russell, SJ; Selagamsetty, R; Sinha, M; Zheng, H | 1 |
| Cummins, MJ; Haymond, MW; Kinzell, J; McKay, S; Newswanger, B; Prestrelski, S; Redondo, MJ | 1 |
| Beck, RW; Bethin, KE; DiMeglio, LA; Dulude, H; Foster, NC; Fox, LA; Marcovina, SM; Meng, L; Nathan, BM; Piché, CA; Rampakakis, E; Rickels, MR; Ruedy, KJ; Schatz, DA; Sherr, JL; Tamborlane, WV; Wadwa, RP | 1 |
| Blauw, H; DeVries, JH; Koops, R; van Bon, AC | 1 |
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| Deutsch, T; Dió, M; Mészáros, J | 1 |
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| Dey, A; Grise, KN; McDonald, MW; Melling, CW; Murray, MR; Noble, EG; Olver, TD; Shoemaker, JK | 1 |
| Cantwell, M; Heptulla, RA; Ilkowitz, JT; Katikaneni, R; Ramchandani, N | 1 |
| Fligner, CL; Foulis, AK; Hull, RL; Mei, Q; Mundinger, TO; Taborsky, GJ | 1 |
| Batra, M; Bellini, N; Chaudhuri, A; Dandona, P; Dhindsa, S; Ghanim, H; Green, K; Hejna, J; Kuhadiya, ND; Makdissi, A; Mehta, A; Sandhu, S; Yang, M | 1 |
| Davis, I; Davis, SN; Hedrington, MS; Mikeladze, M; Tate, DB; Younk, LM | 1 |
| Branigan, D; Castle, JR; Cummins, M; Newswanger, B; Prestrelski, S; Shi, L; Strange, P; Youssef, JE | 1 |
| Branigan, D; Castle, JR; Condon, J; Edwards, C; El Youssef, J; Jacobs, PG; Jones, M; Kuehl, K; Leitschuh, J; Preiser, N; Rajhbeharrysingh, U; Ramsey, K; Reddy, R; Resalat, N | 1 |
| Mundinger, TO; Taborsky, GJ | 2 |
| Blauw, H; DeVries, JH; Keith-Hynes, P; Koops, R | 1 |
| Chen, J; Fu, H; Huan, M; Qiu, G; Tian, W | 1 |
| Castle, JR; Emami, A; Haidar, A; Pineau, J; Rabasa-Lhoret, R; Youssef, JE | 1 |
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| Chiasson, JL; Emami, A; Haidar, A; Ladouceur, M; Legault, L; Messier, V; Rabasa-Lhoret, R; Suppere, C; Taleb, N | 1 |
| Clausen, TR; Damm-Frydenberg, C; Holst, JJ; Madsbad, S; Nørgaard, K; Ranjan, A; Schmidt, S; Steineck, I | 1 |
| Hao, E; Kuss, P; Lee, SH; Levine, F; Millán, JL; Newlin, R; Piran, R | 1 |
| Balliro, C; Buckingham, BA; Buse, JB; Clinton, P; Damiano, ER; DeSalvo, D; Dezube, M; Diner, J; Ekhlaspour, L; El-Khatib, FH; Esmaeili, A; Frank, E; Goley, A; Harlan, DM; Hartigan, C; Hillard, MA; Kirkman, MS; Lock, JP; Ly, T; Magyar, KL; Malkani, S; Mondesir, D; Norlander, L; Russell, SJ; Selagamsetty, RR; Sinha, M; Thompson, MJ; Wilson, DM; Young, LA; Zheng, H | 1 |
| Abadie, J; Bach, JM; Blancho, G; Bosch, S; Brouard, S; Conchon, S; Concordet, JP; Cozzi, E; Danna, C; Duchi, R; Gaide, N; Galli, C; Gauthier, O; Guicheux, J; Hervouet, J; Jégou, D; Judor, JP; Lagutina, I; Lazzari, G; Le Bas-Bernardet, S; Le Berre, L; Lévêque, X; Minault, D; Mosser, M; Mouré, A; Perota, A; Pogu, S; Riochet, D; Salama, A; Soulillou, JP; Weiss, P | 1 |
| Haidar, A; Ladouceur, M; Legault, L; Messier, V; Rabasa-Lhoret, R | 1 |
| Grant, JS; Graven, LJ | 1 |
| Chakravarthy, H; Chera, S; Dai, X; Damond, N; Downie, C; Enge, M; Gu, X; Herrera, PL; Kim, SK; Liu, K; MacDonald, PE; Oberholzer, J; Quake, S; Thorel, F; Wang, J; Wang, Y; Xing, Y | 1 |
| Gjymishka, A; Jorgensen, ML; Oh, SH; Petersen, BE; Wasserfall, CH | 1 |
| Eissing, T; Krauss, M; Kupfer, L; Schaller, S; Wadehn, F | 1 |
| Feng, AL; Feng, Q; Gui, L; Kaltsidis, G; Lu, WY; Xiang, YY | 1 |
| Abuaysheh, S; Batra, M; Chaudhuri, A; Dandona, P; Garg, M; Ghanim, H; Green, K; Hejna, J; Kuhadiya, ND; Makdissi, A; Torre, B | 1 |
| Bargiota, A; Braatvedt, GD; Brown, S; Corrall, RJ; Gamble, G; Newrick, PG; Parker, DR | 1 |
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| Deacon, CF; Dunning, BE; Foley, JE; He, YL; Holst, JJ; Kelley, DE; Leone-Jones, A; Ligueros-Saylan, M; Yu, T | 1 |
| Altieri, DC; Altura, RA; Devor-Henneman, D; Dohi, T; Holloway, MP; Jiang, Y; Kusewitt, D; Nishimura, W; Robinson, ML; Sabo, E; Sharma, A; Wang, H | 1 |
| Alejandro, R; Baidal, DA; Cure, PE; Faradji, RN; Froud, T; Mendez, A; Messinger, S; Monroy, K; Pileggi, A; Ponte, GM; Ricordi, C; Selvaggi, G | 1 |
| Battelino, T; Greenbaum, CJ; Haastert, B; Kolb, H; Lachin, JM; Ludvigsson, J; Mandrup-Poulsen, T; McGee, PF; Pozzilli, P | 1 |
| Li, WH; Sun, Q; Wang, H; Wang, T; Xiao, XH; Yang, GH; Yuan, T | 1 |
| Battezzati, A; Benedini, S; DeTaddeo, F; Luzi, L; Maffi, P; Secchi, A; Sereni, LP | 1 |
| Haymond, MW; Heptulla, RA; Mason, KJ; Rodriguez, LM | 3 |
| Park, BH; Unger, RH; Wang, MY; Wang, ZV; Yu, X | 1 |
| Kitatani, N; Kuroe, A; Kurose, T; Ohya, M; Oku, M; Seino, Y; Watanabe, K; Yabe, D | 1 |
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| Almeida, MH; Barone, B; Campos, F; Dantas, JR; Kupfer, R; Milech, A; Oliveira, JE; Rodacki, M; Zajdenverg, L | 1 |
| Brown, S; Cheng, H; Ding, Y; Fan, X; McCrimmon, RJ; McNay, EC; Shaw, M; Sherwin, RS; Vella, MC; Zhou, L | 1 |
| Chase, HP; Lutz, K; Pencek, R; Porter, L; Zhang, B | 1 |
| Beck, R; Becker, DM; Buckingham, B; Fiallo-Scharer, R; Kollman, C; Mauras, N; Ruedy, K; Singh, R; Steffes, M; Tamborlane, W; Tsalikian, E; Weinzimer, S; Xing, D | 1 |
| Cooperberg, BA; Cryer, PE | 3 |
| Kolb, H; Meierhoff, G; Pfleger, C; Schloot, NC | 1 |
| Clarke, W; Dunger, D; Jones, T; Klingensmith, GJ; Rewers, A | 1 |
| Figlewicz, DP; Hackney, DJ; LeBoeuf, R; Mei, Q; Mundinger, TO; Taborsky, GJ | 1 |
| Bryan, J; Harmon, JS; Oseid, EA; Robertson, RP; Slucca, M | 1 |
| Ford, GC; Jaleel, A; Jourdan, M; Kahn, BB; Karakelides, H; Nair, KS | 1 |
| Iida, M; Ishida-Oku, M; Iwase, M; Kitada, H; Masutani, K; Sugitani, A; Tanaka, M | 1 |
| Alejandro, R; Faradji, RN; Froud, T; Mendez, AJ; Messinger, S; Mineo, D; Monroy, K; Pileggi, A; Ricordi, C; Tharavanij, T | 1 |
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| Hare, KJ; Holst, JJ; Knop, FK; Vilsbøll, T | 1 |
| Asmar, M; Bache, M; Holst, JJ; Knop, FK; Madsbad, S | 1 |
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| Asmar, M; Holst, JJ; Kielgast, U; Madsbad, S | 1 |
| Castle, JR; El Youssef, J; Engle, JM; Kagan, R; Massoud, RG; Ward, WK; Yuen, KC | 1 |
| Dietzen, DJ; Green, RP; Hollander, AS; Thevis, M; Thomas, A | 1 |
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| Castle, JR; El Youssef, J; Engle, JM; Massoud, RG; Ward, WK | 2 |
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| Taborsky, GJ | 1 |
| Arato, I; Becchetti, E; Calafiore, R; Calvitti, M; Falabella, G; Fallarino, F; Grohmann, U; Luca, G; Mancuso, F; Nastruzzi, C; Puccetti, P | 1 |
| Arnqvist, H; Berne, C; Björk, E; Bolinder, J; Karlsson, FA; Nyström, L; Schölin, A | 1 |
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| Barbot-Trystram, L; Benabadji, S; Boitard, C; Larger, E; Philippe, MF; Vadrot, D | 1 |
| Holst, JJ; Kielgast, U; Madsbad, S | 1 |
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| Beck-Nielsen, H; Brock Jacobsen, I; Flyvbjerg, A; Frystyk, J; Henriksen, JE; Holst, JJ; Korsholm, L; Vind, BF | 1 |
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| Cherrington, AD; Unger, RH | 1 |
| Castle, JR; El Youssef, J; Ward, WK | 1 |
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| Barron, AE; Beenken-Rothkopf, LN; Davis, NE; Fontaine, MJ; Kaplan, DL; Kojic, N; Mirsoian, A | 1 |
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| Baron, A; Kelemen, D; Ruggles, JA | 1 |
| de Smet, M; Horowitz, M; Rayner, CK; Renooij, W; Samsom, M; Schwartz, MP; Smout, AJ; van Dam, PS; Wishart, JM | 1 |
| Damm, P; Hansen, T; Hornnes, P; Jensen, DM; Lauenborg, J; Locht, H; Mølsted-Pedersen, L; Pedersen, O; Vestergaard, H | 1 |
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| Anderwald, C; Bernroider, E; Brehm, A; Cline, G; Krssak, M; Roden, M; Shulman, GI; Trajanoski, Z | 1 |
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| Barker, CF; Markmann, JF; Mueller, R; Naji, A; Rickels, MR; Schutta, MH; Teff, KL | 1 |
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| Becker, TC; Cao, W; Collins, QF; Collins, S; Daniel, KW; Floering, L; Lupo, EG; Robidoux, J; Xiong, Y | 1 |
| Dubé, MC; Lavoie, C; Prud'homme, D; Weisnagel, SJ | 1 |
| Jobe, LJ; Martin, R; Ryan, GJ | 1 |
| Flores, RL; Galassetti, PR; Iwanaga, K; Larson, JK; Pontello, AM; Zaldivar, FP | 1 |
| Bumbasirevic, V; Canovic, F; Colovic, R; Dimitrijevic-Sreckovic, V; Djordjevic, PB; Dragasevic, M; Gostiljac, D; Jotic, A; Lalic, K; Lalic, N; Lukic, LJ; Markovic, I; Nikolic, D; Paunovic, I; Popovic, S; Rajkovic, N; Raketic, N; Zamaklar, M | 1 |
| Demuth, HU; Kim, SJ; McIntosh, CH; Pederson, RA; Pospisilik, JA | 1 |
| Crisostomo, M; Galassetti, PR; Iwanaga, K; Larson, J; Pescatello, A; Zaldivar, FP | 1 |
| Bussau, VA; Ferreira, LD; Fournier, PA; Jones, TW | 1 |
| Bernroider, E; Bischof, MG; Brehm, A; Krebs, M; Krssák, M; Mlynárik, V; Roden, M | 1 |
| Cotterill, AM; Hartley, M; Thomsett, MJ | 1 |
| Cheng, H; Fan, X; McCrimmon, RJ; McNay, EC; Routh, VH; Sherwin, RS; Song, Z; Weikart-Yeckel, C | 1 |
| Kurland, IJ; Pei, L; Tontonoz, P; Vaitheesvaran, B; Waki, H; Wilpitz, DC | 1 |
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| Kapoor, S; Markmann, JF; Mueller, R; Naji, A; Rickels, MR; Schutta, MH; Teff, KL | 1 |
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| Brooks-Worrell, B; Chiu, H; Felton, J; Goel, A; Palmer, JP | 1 |
| Abraham, NG; Guo, K; Husney, D; Ikehara, S; Inaba, M; Kappas, A; Li, M; Morita, T; Patil, K; Peterson, S; Terada, E | 1 |
| Chiarelli, F; Hansen, L; Holst, JJ; Hougaard, P; Kaas, A; Kocova, M; Mortensen, HB; Nielsen, LB; Orskov, C; Ploug, KB; Pörksen, S | 1 |
| Chiarelli, F; de Beaufort, C; Gammeltoft, S; Hansen, L; Holl, R; Holst, JJ; Hougaard, P; Jansen-Olesen, I; Mortensen, HB; Nielsen, LB; Ploug, KB; Pörksen, S; Rorsman, P; Swift, P; Ørskov, C | 1 |
| Ando, H; Kaneko, S; Kato, K; Kurita, S; Sakurai, M; Shimizu, A; Takamura, T; Tsuchiyama, N | 1 |
| Bollyky, J; Greenbaum, CJ | 1 |
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| Brismar, K; Efendic, S; Lehtihet, M | 1 |
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| Bolli, GB; Busciantella Ricci, N; Candeloro, P; Cioli, P; Fanelli, CG; Nair, KS; Porcellati, F; Rossetti, P; Santeusanio, F | 1 |
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| Crespo Pinilla, J; Fermoso García, J; González Sarmiento, E | 1 |
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| Gepts, W; Pipeleers, D; Smets, G; Van De Winkel, M | 1 |
| Drenck, CR; Klöppel, G | 1 |
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| Lager, I | 2 |
| Alvestrand, A; Bergström, J | 1 |
| Besch, W; Heinke, P; Ratzmann, KP; Schulz, B | 1 |
| Garrow, JS; Halliday, D; Nair, KS | 1 |
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| DeFronzo, RA; Ferrannini, E; Hendler, R; Juhlin-Dannfelt, A; Koivisto, V; Sherwin, RS; Simonson, DC | 1 |
| Chenon, D; Colette, C; Mirouze, J; Monnier, LH; Orsetti, A; Phaka, M | 1 |
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| Kolb, E | 1 |
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| Assan, R; Boitard, C; Debray-Sachs, M; Hamburger, J; Saï, P | 1 |
| Angeletti, G; Bolli, G; Brunetti, P; De Cosmo, S; De Feo, P; Gerich, JE; Perriello, G; Santeusanio, F; Ventura, MR | 1 |
| Bolli, G; Brunetti, P; Compagnucci, P; De Cosmo, S; De Feo, P; Perriello, G; Santeusanio, F; Unger, RH | 1 |
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| Kerner, W; Navascués, I; Pfeiffer, EF; Torres, AA | 1 |
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| Maclaren, NK; Neufeld, M; Ozand, PT; Riley, WJ; Unger, RH; Winter, WE | 1 |
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| Baker, BA; Bolli, GB; Cryer, PE; Dimitriadis, GD; Gerich, JE; Haymond, MW; Pehling, GB | 1 |
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| Benedetti, MM; Bolli, GB; Brunetti, P; De Cosmo, S; De Feo, P; Gerich, JE; Perriello, G; Santeusanio, F; Ventura, MM | 1 |
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| Krarup, T; Madsbad, S; Tronier, B | 1 |
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| Cline, GW; Hwang, JH; Magnusson, I; Perseghin, G; Petersen, KF; Rothman, DL; Shulman, GI | 1 |
| Elliott, EA; Flavell, RA | 1 |
| Cryer, P; Gerich, J; Korytkowski, M; Mitrakou, A; Mokan, M; Ryan, C; Veneman, T | 1 |
| Battezzati, A; Bianchi, E; Di Carlo, V; Luzi, L; Perseghin, G; Pozza, G; Secchi, A; Spotti, D; Vergani, S | 1 |
| Guberski, DL; Like, AA; Stubbs, M | 1 |
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| Hirose, H; Ito, K; Kido, K; Koyama, K; Maruyama, H; Saruta, T; Tashiro, Y | 1 |
| Amiel, SA; Cranston, I; Lomas, J; Macdonald, I; Maran, A | 1 |
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| Andreani, D; Baroni, MG; Boccuni, ML; Buzzetti, R; Cavallo, MG; Fioriti, E; Lucentini, L; Pozzilli, P; Signore, A; Visalli, N | 1 |
| Cryer, PE; Dagogo-Jack, S; Rattarasarn, C | 1 |
| Lewis, GF; Polonsky, KS; Steiner, G; Weller, B; Zinman, B | 1 |
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| Blankenstein, MA; Hackeng, WH; Höppener, JW; Lips, CJ; Nieuwenhuis, MG; van Hulst, KL; van Jaarsveld, BC | 1 |
| Kääpä, P; Knip, M; Koivisto, M | 1 |
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| Huang, X; Hully, J; Hultgren, B; MacLachlan, NJ; Pitts-Meek, S; Stewart, TA | 1 |
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| De Sio, G; Ippoliti, M; Monteburini, T; Recchioni, A; Refe, A; Testa, I; Testa, R | 1 |
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| Bruijn, JA; Frölich, M; Gooszen, HG; Guicherit, OR; Lemkes, HH; Tamsma, JT; van der Woude, FJ | 1 |
| de Boer, SY; Fröhlich, M; Jansen, JB; Lam, WF; Lamers, CB; Lemkes, HH; Masclee, AA; Schipper, J | 1 |
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| Burcharth, F; Christiansen, E; Madsbad, S; Rasmussen, K; Tibell, A; Tydén, G | 1 |
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| Cryer, PE; Dagogo-Jack, S; Rattarasarn, C; Zachwieja, JJ | 1 |
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| Aman, J; Stenninger, E | 1 |
| Powell, AM; Sherwin, RS; Shulman, GI | 1 |
| Chauvet, D; Darmaun, D; Leblanc, H; Robert, JJ | 1 |
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| Boden, G; Hoeldtke, RD | 1 |
| Fernlund, P; Gottsäter, A; Landin-Olsson, M; Lernmark, A; Sundkvist, G | 1 |
| Balint-Peric, LA; Prelevic, GM; Sönksen, PH; Wheeler, M; Wurzburger, MI | 1 |
| Baartz, A; Baartz, T; Becker, HD; Büsing, M; Creutzfeldt, W; Hopt, UT; Nauck, MA; Orskov, C; Siegel, EG; Talartschik, J | 1 |
| Arnqvist, H; Asplund, J; Olsson, PO | 1 |
| Lassmann-Vague, V; Mercier, P; Pieron, H; Thirion, X; Vague, P; Vialettes, B; Zevaco-Mattei, C | 1 |
| Cryer, PE; Wiethop, BV | 2 |
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| Ahlfors, K; Ivarsson, SA; Lindberg, B; Nilsson, KO; Svanberg, L | 1 |
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| Johansson, BL; Kernell, A; Sjöberg, S; Wahren, J | 1 |
| Aoki, TT; Foss, MC | 1 |
| Christiansen, E; Madsbad, S; Rasmussen, K; Tibell, A; Tydén, G | 1 |
| Craft, S; Cryer, PE; Dagogo-Jack, SE | 1 |
| Bendtson, I; Binder, C; Rosenfalck, AM | 1 |
| Caprio, S; Gerow, K; Sherwin, RS; Tamborlane, WV; Zych, K | 1 |
| Penhale, WJ; Stumbles, PA | 1 |
| Ahern, JA; Gatcomb, PM; Held, NA; Petit, WA; Tamborlane, WV | 1 |
| Hanafusa, T; Kono, N; Namba, M; Tarui, S | 1 |
| Adamson, U; Clausen-Sjöbom, N; Lins, PE; Liu, D | 1 |
| Akimoto, K; Hayakawa, K; Matsukura, S; Nakazato, M | 1 |
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| Cónsole, GM; Dardenne, M; Gómez Dumm, CL; Goya, RG; Luna, GC | 1 |
| Brkić, S; Dimitrijević, V; Dordević, PB; Dragasević, M; Jotić, A; Lalić, K; Lalić, NM; Paunović, I; Popović, S; Zamaklar, M | 1 |
| Ebeling, P; Koivisto, VA; Seppälä, M; Stenman, UH | 1 |
| Andersson, DE; Eriksson, B; Stridsberg, M; Svartberg, J; Wilander, E | 1 |
| Allen, WT; Johnson, KH; Johnston, SD; Root, MV | 1 |
| Damm, P; Hornnes, P; Kühl, C; Mølsted-Pedersen, L | 1 |
| Khoury, JC; Miodovnik, M; Rosenn, BM; Siddiqi, TA | 1 |
| Cirulli, V; Hayek, A; Mally, MI; Otonkoski, T; Soto, G | 1 |
| Chaillous, L; Charbonnel, B; Guilhem, I; Lecomte, P; Maréchaud, R; Marre, M; Maugendre, D; Rohmer, V; Saï, P | 1 |
| Gill, RG; Kam, I; Lafferty, KJ; Stegall, MD | 1 |
| Bossinakou, I; Grigorakis, S; Iliopoulou, E; Kontessis, PA; Papantoniou, A; Roussi, D; Sarika, L; Souvatzoglou, A; Stipsanelli, K; Trevisan, R | 1 |
| Ellerman, KE; Guberski, DL; Like, AA; Richards, CA; Shek, WR | 1 |
| Avogaro, A; Calabrò, A; Crepaldi, C; Crepaldi, G; Macdonald, I; Milan, D; Pavan, P; Piarulli, F; Sacerdoti, D; Scognamiglio, R; Tiengo, A; Valerio, A | 1 |
| Durinovic-Bellò, I; Hummel, M; Ziegler, AG | 1 |
| Beers, TR; Butler, PC; Gray, RO; Kryshak, EJ; Rizza, RA | 1 |
| Battezzati, A; Bianchi, E; Brambilla, E; Brandhorst, D; Brandhorst, H; Bretzel, RG; Di Carlo, V; Falqui, L; Federlin, K; Gennari, L; Hering, BJ; Luzi, L; Maffi, P; Mazzaferro, V; Perseghin, G; Pozza, G; Raptis, G; Regalia, E; Secchi, A; Socci, C; Terruzzi, I | 1 |
| Brand, CL; Holst, JJ; Jørgensen, PN; Svendsen, I | 1 |
| Liu, D; McManus, RM; Ryan, EA | 1 |
| Bartocci, L; Bolli, GB; Brunetti, P; Ciofetta, M; Del Sindaco, P; Ialli, C; Lepore, M; Pampanelli, S; Torlone, E | 1 |
| Assan, R; Boitard, C; Deschamps, I; Jos, J; Laborde, K; Rakotoambinina, B; Robert, JJ; Timsit, J | 1 |
| Creutzfeldt, WO; Holst, JJ; Kleine, N; Nauck, MA; Orskov, C; Willms, B | 1 |
| Craen, M; Decraene, P; Falorni, A; Foriers, A; Gorus, FK; Pipeleers, DG; Schuit, FC; Semakula, C; Sodoyez, JC; Van Schravendijk, CF; Vandewalle, CL | 1 |
| Clarke, WL; Cox, DJ; Gonder-Frederick, LA; Julian, DM | 1 |
| Ashworth, L; Chevalier, A; Guyon, F; M'bemba, J; Medlej, R; Selam, JL; Slama, G | 1 |
| Chin, DT | 1 |
| Becker, HD; Benz, S; Büsing, M; Gwodzinski, A; Hopt, UT; Nauck, MA; Pfeffer, F; Zink, R | 1 |
| Annibale, B; Bartocci, L; Bolli, GB; Brunetti, P; Ciofetta, M; Di Vincenzo, A; Epifano, L; Fanelli, C; Lalli, C; Lepore, M; Modarelli, F; Pampanelli, S; Rambotti, AM; Sindaco, PD | 1 |
| Carroll, R; Chan, SJ; Gong, Q; Martin, S; Rouillé, Y; Steiner, DF | 1 |
| Kida, H; Kobayashi, K; Nagai, Y; Noto, Y; Ohsawa, K; Taniguchi, M; Yamagishi, S; Yamamoto, Y | 1 |
| Diuzheva, TG; Dokuchayev, KV; Galperin, EI; Gitel, EP; Kuzovlev, NF; Petrovsky, PF; Platonova, LV; Rabinovich, SE | 1 |
| Berne, C; Björk, E; Kämpe, O; Karlsson, FA; Oskarsson, P; Wibell, L | 1 |
| Birkenholz, M; Kabadi, M; Kabadi, UM; McCoy, S | 1 |
| Bolli, G; Brunetti, P; Del Sindaco, P; Di Vincenzo, A; Epifano, L; Kassi, G; Lalli, C; Modarelli, F; Pampanelli, S; Perriello, G; Rambotti, AM; Torlone, E | 1 |
| Odawara, M; Yamashita, K | 1 |
| Kolterman, O; Moyses, C; Young, A | 1 |
| Erbaş, T; Gedik, O; Gürlek, A; Sayinalp, S | 1 |
| Bizzarro, A; Capaldo, B; Corigliano, G; De Bellis, A; Di Bonito, P; Pace, E; Turco, S | 1 |
| De Mauro, M; Le Moli, R; Lunetta, M; Nicoletti, F | 1 |
| Flavell, RA; Grewal, IS; Grewal, KD; Janeway, CA; Picarella, DE; Wong, FS | 1 |
| Geyer, R; Laube, H; Linn, T; Prassek, S | 1 |
| Dziura, J; Jacob, RJ; Morgen, JP; Sherwin, RS; Shulman, GI | 1 |
| Holst, JJ; Nauck, M; Orskov, C; Toft-Nielsen, MB; Willms, B | 1 |
| Giacca, A; Kawamori, R; Lekas, M; Matsuhisa, M; Rodgers, CD; Shi, ZQ; Vranic, M; Wan, C | 1 |
| Alberti, KG; Bhat, DS; Hockaday, TD; Naik, SS; Orskov, H; Raut, KN; Sardesai, BS; Shelgikar, KM; Yajnik, CS | 1 |
| Behme, MT; Dupré, J; Hramiak, IM; McDonald, TJ | 1 |
| Berghöfer, P; Fehmann, HC; Göke, B; Peterson, RG; Schneider, K | 1 |
| Cooke, A; Edlund, H; Fulford, T; Gu, D; O'Reilly, LA; Phillips, JM; Sarvetnick, N | 1 |
| Ebeling, P; Koivisto, VA; Tuominen, JA; Vuorinen-Markkola, H | 1 |
| Giacca, A; Lewis, GF; Vranic, M | 1 |
| Bolli, GB; Boschetti, E; Bottini, P; Brunetti, P; Ciofetta, M; Del Sindaco, P; Pampanelli, S; Scionti, L | 1 |
| Becher, T; El-Hag, O; Fischer, U; Freyse, EJ; Göke, B; Knospe, S | 1 |
| Bendayan, M; Park, IS | 1 |
| Hanafusa, T; Imagawa, A; Itoh, N; Kono, N; Kuwajima, M; Matsuzawa, Y; Miyagawa, J; Waguri, M | 1 |
| Kuikka, JT; Turpeinen, AK; Uusitupa, MI; Vanninen, E | 1 |
| Apostolova, MD; Choo, KH; Michalska, AE; Tohyama, C | 1 |
| Bourque, J; Chiasson, JL; Ducros, F; el Achkar, GG; Maheux, P | 1 |
| Bolli, GB; Bottini, P; Brunetti, P; Ciofetta, M; Del Sindaco, P; Di Vincenzo, A; Fanelli, C; Lalli, C; Lepore, M; Pampanelli, S; Porcellati, F | 1 |
| Birkeland, K; Bjørgaas, M; Jorde, R; Sager, G; Sand, T; Vea, H; Vik, T | 1 |
| Bonadonna, RC; DeFronzo, RA; Del Prato, S; Groop, LC; Leonetti, F; Matsuda, M; Sheehan, P; Simonson, DC | 1 |
| Gerich, JE; Meyer, C; Mitrakou, A; Nadkarni, V; Stumvoll, M | 1 |
| Field, CJ; McBurney, MI; Reimer, RA | 1 |
| Adamson, U; Johansson, BL; Lins, PE; Oskarsson, P | 1 |
| Di Mauro, M; Le Moli, R; Lunetta, M | 1 |
| Finney, LS; Finney, MO; Gonzalez, JM | 1 |
| Eisfelder, B; Schnell, O; Standl, E; Ziegler, AG | 1 |
| Gil, MJ; Goñi, F; Goñi, MJ; Moncada, E; Monreal, M; Salvador, J; Sopena, M | 1 |
| Benz, S; Erb, M; Gwodzinski, A; Hopt, UT; Nauck, MA; Pfeffer, F | 1 |
| Alejandro, R; Bourgoignie, JJ; Fernandez, LA; Kenyon, NS; Lehmann, R; Ricordi, C; Wagner, JL | 1 |
| Cheetham, T; Crowne, EC; Dunger, DB; Holly, JM; Samra, JS; Watts, A | 1 |
| Daimon, M; Ikezawa, Y; Manaka, Y; Ohnuma, H; Saito, K; Sasaki, H; Seino, T; Takahashi, K; Yamatani, K | 1 |
| Aman, J; Schollin, J; Stenninger, E | 1 |
| De Riva, C | 1 |
| Di Mauro, M; Le Moli, R; Lunetta, M; Nicoletti, F | 1 |
| Drucker, DJ | 1 |
| Carmellini, M; Coppelli, A; Del Guerra, S; Giannarelli, R; Lencioni, C; Lorenzetti, M; Lupi, R; Marchetti, P; Marselli, L; Mosca, F; Navalesi, R; Tellini, C | 1 |
| Barnie, A; Chiasson, JL; Simkins, S; Strack, T; Tildesley, H; Tsui, EY; Zinman, B | 1 |
| Berne, C; Björk, E; Karlsson, FA | 1 |
| Christensen, NJ; Hilsted, J; Hvidberg, A | 1 |
| Bouwens, L; Delvaux, G; Gorus, FK; Grupping, A; Hendrieckx, C; Keymeulen, B; Ling, Z; Pipeleers, DG; Pipeleers-Marichal, M; Salmela, K; Van Schravendijk, C | 1 |
| Ahrén, B; Havel, PJ; Taborsky, GJ | 1 |
| Field, CJ; Glen, S; McBurney, MI; Reimer, RA | 1 |
| Itakura, M; Kikutani, H; Komagata, Y; Miyazaki, J; Moritani, M; Sano, T; Tanaka, C; Wong, SF; Yamaoka, T; Yoshimoto, K | 1 |
| Caffarri, G; Caiazza, A; Capretti, L; Chiodera, P; Coiro, V; Giuliani, N; Volpi, R | 1 |
| Brandhorst, D; Brandhorst, H; Bretzel, RG; Federlin, K; Gerich, J; Grossmann, R; Hering, BJ; Meyer, C | 1 |
| Bajaj, M; Kinsley, BT; Levy, CJ; Simonson, DC | 1 |
| Cryer, PE; Dence, CS; Fanelli, CG; Markham, J; Paramore, DS; Powers, WJ; Videen, TO | 1 |
| Chiasson, JL; Launay, B; Strack, T; Tildesley, HD; Zinman, B | 1 |
| Couch, RM; Elliott, JF; Marlin, KL | 1 |
| Koeslag, JH; Saunders, PT; Wessels, JA | 1 |
| Charlton, MR; Nair, KS | 1 |
| Bretzel, RG; Gerich, J; Grossmann, R; Mahler, R; Meyer, C; Mitrakou, A; Veneman, T | 1 |
| Craft, S; Cryer, PE; Fanelli, CG; Hershey, T; Ovalle, F; Paramore, DS; Terkamp, C | 1 |
| Nauck, MA | 1 |
| Daimon, M; Igarashi, M; Ikezawa, Y; Manaka, H; Ogawa, A; Ohnuma, H; Sasaki, H; Yamatani, K | 1 |
| Acerini, CL; Dunger, DB; Harris, DA; Matyka, KA; Russell-Jones, DL; Umpleby, AM; Watts, AP | 1 |
| Stegall, MD | 1 |
| Bonner-Weir, S; Hollister-Lock, J; Quickel, RR; Tatarkiewicz, K; Ulrich, TR; Weir, GC; Yoon, KH | 1 |
| Bargiota, A; Braatvedt, GD; Corrall, RJ; Halliwell, M; Parker, DR | 1 |
| Becher, T; El Hag, O; Fischer, U; Freyse, EJ; Göke, B; Knospe, S | 1 |
| Borg, MA; Borg, WP; Brines, ML; Sherwin, RS; Shulman, GI; Tamborlane, WV | 1 |
| Freed, CR; Hurlbert, MS; Hutton, JC; Kaddis, FG; Wasmeier, C; Zhou, W | 1 |
| Armstrong, E; Blackshaw, PE; Buchanan, KD; Horowitz, M; King, P; Kong, MF; Macdonald, IA; Perkins, AC; Tattersall, RB | 1 |
| Barrett, EJ; Miers, WR | 1 |
| Isotani, H; Kameoka, K | 1 |
| Hamaguchi, T; Hanafusa, T; Higashiyama, S; Horikawa, Y; Imagawa, A; Iwahashi, H; Matsuzawa, Y; Miyagawa, J; Miyazaki, J; Nakajima, H; Namba, M; Okita, K; Oue, T; Satoh, T; Yamagata, K; Yamamoto, K; Yamasaki, T; Yang, Q; Yoshiuchi, I | 1 |
| Crowne, EC; Dunger, DB; Havel, PJ; Macdonald, IA; Matthews, D; Matyka, KA | 1 |
| Brandão-Neto, J; da Cunha, NF; da Silva, CA; Dourado, FB; Figueiredo, NB; Naves, LA; Shuhama, T | 1 |
| Alberti, KG; Gravholt, CH; Hove, KY; Kolterman, O; Moyses, C; Møller, N; Nyholm, B; Orskov, L; Schmitz, O | 1 |
| Bohrer, A; Cryer, PE; Dagogo-Jack, S; Halban, PA; Powderly, WG; Sigmund, C; Tebas, P; Turk, J; Yarasheski, KE | 1 |
| McCrimmon, RJ; Sherwin, RS | 1 |
| Franzese, A; Laforenza, U; Patrini, C; Poggi, V; Tenore, A; Valerio, G | 1 |
| Gravholt, CH; Møller, N; Nyholm, B; Orskov, L; Schmitz, O; Yde Hove, K | 1 |
| Adamson, UC; Ahré, B; Lins, PE; Oskarsson, PR | 1 |
| Adamson, UC; Lins, PE; Oskarsson, PR; Wallberg Henriksson, H | 1 |
| Carlsson, A; Groop, L; Sundkvist, G; Tuomi, T | 1 |
| Borrello, E; Di Biase, N; Fallucca, F; Napoli, A; Sabbatini, A; Sciullo, E | 1 |
| Chevalier, A; M'Bemba, J; Selam, JL; Slama, G; Sola, A; Taverna, MJ | 1 |
| Beyer, J; Burchert, D; Kann, P; Kunt, T; Küstner, E; Sarnighausen, HE; Schneider, S | 1 |
| Sélam, JL | 1 |
| Andereggen, E; Bühler, L; Crétin, N; Fournier, B; Goumaz, C; Lou, J; Mage, R; Morel, P; Oberholzer, J; Philippe, J; Triponez, F | 1 |
| Adamson, UC; Backman, L; Lins, PE; Oskarsson, PR | 1 |
| Chan, JC; Cockram, CS; Li, JK; Mackay, IR; Rowley, MJ; Zimmet, PZ | 1 |
| Efendic, S; Hellström, P; Holst, JJ; Juntti-Berggren, L; Pigon, J | 1 |
| Del Guerra, S; Di Mario, U; Dotta, F; Ling, Z; Lupi, R; Marchetti, P; Marselli, L; Navalesi, R; Realacci, M; Santangelo, C | 1 |
| Costa, F; Davis, SN; Shavers, C | 1 |
| Karanam, M; Krissansen, G; Neve, J; Nitschke, K; Poole, CA; Reddy, S; Ross, JM | 1 |
| Boyd, R; Foëx, B | 1 |
| Heinze, HJ; Lehnert, H; Lobmann, R; Pottag, G; Smid, HG; Wagner, K | 1 |
| Hansen, JB; Hornum, L; Mandrup-Poulsen, T; Markholst, H; Rasmussen, SB; Sørensen, TS | 1 |
| Abitbol, C; Berkovitz, G; Eidson, M; Leal, D; Seeherunvong, T; Seeherunvong, W | 1 |
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| Barilli, AL; Dei Cas, A; Dell'Anna, C; Gnudi, A; Iotti, M; Lugari, R; Marani, B; Orlandini, A; Ugolotti, D; Zandomeneghi, R | 1 |
| Barberio, S; Bruttomesso, D; Crazzolara, D; Del Prato, S; Fongher, C; Iori, E; Marescotti, MC; Pianta, A; Silvestri, B; Tiengo, A; Valerio, A | 1 |
| Flores, RM; Haigwood, JT; Kelley, KM; Mazloumi, R; Ngan, G | 1 |
| Askari, H; Dagogo-Jack, S; Kim, B; Lehner, LL; Morrill, B; Sha, X | 1 |
| Burge, MR; Garcia, N; Qualls, CR; Schade, DS | 1 |
| Basu, A; Basu, R; Camilleri, M; Holst, JJ; Rizza, RA; Schwenk, FW; Shah, P; Vella, A | 1 |
| Aihara, H; Kawamoto, S; Miyazaki, J; Nariuchi, H; Nitta, Y; Tabayashi, K; Tashiro, F; Yoshimoto, T | 1 |
| Bernroider, E; Bischof, MG; Krebs, M; Krssak, M; Roden, M; Stingl, H; Waldhäusl, W | 1 |
| Haymond, MW; Schreiner, B | 1 |
| Ahern, JA; Bronson, M; Coraluzzi, L; Monsod, TP; Tamborlane, WV; Yong-Zhan, T | 1 |
| Dong, H; McEvoy, R; Meseck, M; Morral, N; Thung, SN; Woo, SL | 1 |
| Brandão-Neto, J; Oba, L; Shuhama, T; Silva, CA; Silva, JA | 1 |
| Contesse, J; Reinhart, WH; Rohrer, A; Schnyder, L; Walter, R | 1 |
| Borg, H; Fernlund, P; Gottsäter, A; Landin-Olsson, M; Sundkvist, G | 1 |
| Aaen, K; Bock, T; Buschard, K; Hageman, I; Hansen, MW; Hansen, SV; Josefsen, K; Jørgensen, M; Kjaer, TW; Pedersen, CR | 1 |
| Alvès, V; Coulaud, J; Drexhage, HA; Durant, S; Esling, A; Homo-Delarche, F; Pelegri, C; Pléau, JM; Rosmalen, JG; Throsby, M | 1 |
| Carlés, C; Carmona, E; Fajardo, C; Merino, JF; Piñón, F; Sánchez-Cuenca, JM | 1 |
| Bak, JF; Kaal, A; Lund, S; Møller, N; Nyholm, B; Orskov, L; Schmitz, O | 1 |
| Chyun, D; Lee, FA; Pfeifer, MA; Rife, F; Russell, RR; Sherwin, RS; Song, S; Tamborlane, WV; Wackers, FJ; Young, LH | 1 |
| Hardy, KJ; McNulty, SJ | 1 |
| Cavan, DA; Jenkins, E; Kerr, D; Sherwin, RS; Turner, BC | 1 |
| Becker, C; Bühler, L; Caulfield, A; Cretin, N; Fournier, B; Morel, P; Philippe, J | 1 |
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| Clemente, F; Puente, J; Redondo, A; Valverde, I; Villanueva-Peñacarrillo, ML | 1 |
| Crino, A; Gross, TM; Jeng, LM; Mesturino, CA; Pozzilli, P; Visalli, N | 1 |
| Cooney, SK; Puhlman, ME; Short, RA; Tuttle, KR | 1 |
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| Christensen, SE; Hansen, AP; Lundbaek, K; Weeke, J | 1 |
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| Josefsberg, Z; Kauli, R; Klonitzki-Peleg, S; Laron, Z; Pertzelan, A; Silbergeld-Kowadlo, A | 1 |
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| Adamson, UC; Andréasson, K; Kollind, ME; Lins, PE; Liu, DT; Moberg, EA | 1 |
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| Alberti, KG; Mengel, A; Møller, N; Orskov, L; Pedersen, O; Rasmussen, O; Schmitz, O; Seefeldt, T | 1 |
| Diem, P; Robertson, RP; Sutherland, DE | 1 |
| Abendroth, D; Fiedler, F; Illner, WD; Land, W; Landgraf, R; Nusser, J; Riepl, RL | 1 |
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| Beylot, M; Chambrier, C; Cohen, R; Cotisson, A; Laville, M; Mornex, R; Picard, S; Vidal, H | 1 |
| Diem, P; Robertson, RP | 1 |
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| Bendtson, I; Binder, C; Gade, J; Rosenfalck, AM; Thomsen, CE; Wildschiødtz, G | 1 |
| Shamoon, H; Shilo, S; Sotsky, M | 1 |
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| Christensen, NJ; Damkjaer Nielsen, M; Hilsted, J; Larsen, S; Philipsen, EK; Tronier, B; Worning, H | 1 |
| Caruso, M; Divertie, GD; Jensen, MD; Miles, JM | 1 |
| Adamson, U; Lins, PE; Sjöbom, NC; Theodorsson, E | 1 |
| Bolinder, J; Groth, CG; Linde, B; Ostman, J; Tydén, G; Wahrenberg, H | 1 |
| Heiling, VJ; Jensen, MD; Miles, JM | 1 |
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| Karanko, H; Koivisto, VA; Leino, A; Marniemi, J; Puukka, P; Rönnemaa, T | 1 |
| Dupre, J; Jenner, MR; Mahon, JL; Purdon, C; Rodger, NW; Stiller, CR | 1 |
| Damkjaer Nielsen, M; Hilsted, J; Larsen, S; Philipsen, EK; Tronier, B; Worning, H | 1 |
| Faber, OK; Gjessing, HJ; Pedersen, O; Reinholdt, B | 1 |
| Duckworth, WC; Langnas, AN; Larsen, JL; Marujo, WC; Ozaki, C; Stratta, RJ; Taylor, RJ; Wahl, TO; Wood, RP; Zorn, BH | 1 |
| Caprio, S; Diamond, M; Gerety, G; Jacob, R; Jones, T; Sherwin, RS; Tamborlane, WV | 1 |
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| Almdal, TP; Jensen, T; Vilstrup, H | 1 |
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| Ziegler, B; Ziegler, M | 1 |
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| Keilacker, H; Kohnert, KD; Michaelis, D; Rjasanowski, I; Woltanski, KP; Ziegler, B; Ziegler, M | 1 |
| Boriani, F; Cacciari, E; Cicognani, A; Giambiasi, E; Mantovani, W; Pascucci, MG; Puglioli, R; Salardi, S; Tacconi, M; Tazzari, R | 1 |
| Clutter, WE; Cryer, PE; Havlin, CE; Hirsch, IB; Shah, SD; Smith, LJ | 1 |
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| Aguilar, M; Escobar-Jiménez, F; Gómez-Villalba, R; Herrera Pombo, JL; Nuñez del Carril, J; Rovira, A | 1 |
| Castellino, P; DeFronzo, RA; Luzi, L; Petrides, AS; Simonson, DC | 1 |
| Ferguson, RM; Henry, ML; O'Dorisio, TM; Osei, K; Sommer, BG; Tesi, RJ | 1 |
| Bach, JF; Boisson, C; Boitard, C; Bougnères, PF; Carel, JC; Chaussain, JL; Frament, N; Landais, P | 1 |
| Ditschuneit, H; Glasbrenner, B; Kerner, W; Malfertheiner, P; Scherbaum, WA | 1 |
| Battezzati, A; Castoldi, R; Di Carlo, V; Facchini, F; Ferrari, G; Luzi, L; Pozza, G; Secchi, A; Spotti, D; Staudacher, C | 1 |
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| Abendroth, D; Illner, WD; Land, W; Landgraf, R; Landgraf-Leurs, MM; Loy, A; Nusser, J | 1 |
| Clarke, BF; Collier, A; Hepburn, DA; Patrick, AW; Robertson, C; Steedman, DJ | 1 |
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| Anastasio, P; Capasso, G; Capodicasa, G; Castellino, P; Coppola, S; De Santo, NG; Giordano, C; Perna, A; Salvatore, T; Torella, R | 1 |
| Bouma, DJ; Hart, JS; Phillipson, BE; Riddle, MC; Youker, G | 1 |
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| Campbell, DA; Dafoe, DC; Lloyd, RV; Merion, RM; Turcotte, JG; Vinik, AI | 1 |
| Caruso, M; Heiling, V; Jensen, MD; Miles, JM | 1 |
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| Casamitjana, R; Goday, A; Gomis, R; Montaña, E; Rosel, P; Soler, J | 1 |
| George, SR; Grossman, LD; Shumak, SL; Singer, W; Zinman, B | 1 |
| Hillebrand, G; Kampik, A; Lachenmayr, B; Landgraf, R; Landgraf-Leurs, MM; Müller, W; Nusser, J; Schleibner, S; Thurau, S; Ulbig, M | 1 |
| Berger, W; Caduff, F; Klopfstein, M; Vonesch, HJ | 1 |
| Kallio, V; Laakso, M; Pyörälä, K; Rönnemaa, T; Sarlund, H | 1 |
| Cataland, S; Craig, EL; Malarkey, WB; O'Dorisio, TM; Osei, K | 1 |
| Castillo, MJ; Gualda, P; Lefebvre, PJ; Scheen, AJ | 1 |
| Faber, OK; Frøland, A; Gjessing, HJ; Matzen, LE | 1 |
| Atiea, JA; Creagh, F; Owens, DR; Page, M; Peters, JR; Scanlon, MF | 1 |
| Lefèbvre, P; Paolisso, G; Scheen, A | 1 |
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| Alberti, KG; Chan, E; Charles, MA; Hanna, M; Jeandidier, N; Kashyap, M; Lozano, J; Selam, JL; Turner, D | 1 |
| Alberetto, M; Calderara, A; Pajetta, E; Pontiroli, AE; Pozza, G | 1 |
| Aoki, T; Benn, J; Berger, M; Gerich, J; Heinemann, L; Hohmann, A; Kelley, D; Ritzenhoff, A; Sönksen, P; Sonnenberg, GE | 1 |
| Gillet, J; Guiot, J; Henrivaux, P; Jandrain, B; Lefèbvre, PJ; Rosenthaler, J; Scheen, AJ | 1 |
| Heaton, DA; Lazarus, NR; Leslie, RD; Pyke, DA | 1 |
| Hirota, M; Idegami, K; Ikei, S; Katafuchi, S; Kiyohara, H; Mishima, M; Mori, K; Nakashima, Y; Sakamoto, K; Yamane, T | 1 |
| Itoh, H; Kono, N; Tarui, S | 1 |
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| Bottazzo, GF; Casamitjana, R; Ercilla, G; Gomis, R; Peig, M; Pujol-Borrell, R | 1 |
| Binder, C; Bolli, GB; Cherrington, AD; Cryer, PE; Gale, EA; Gerich, JE; Sherwin, RS | 1 |
| Beastall, GH; Fisher, BM; Frier, BM; Gray, CE | 2 |
| Bolli, GB; Campbell, PJ; Cryer, PE; Gerich, JE | 1 |
| Bergua, M; Casamitjana, R; Fernandez-Castaner, M; Figuerola, D; Levy, I; Rios, M; Rivera, F; Webb, S | 1 |
| Cryer, PE; Gerich, JE | 1 |
| Dahl-Jørgensen, K; Hanssen, KF; Norman, N; Skare, S | 1 |
| Dimitriadis, G; Gerich, J | 1 |
| Doorenbos, H | 1 |
| Bonner-Weir, S; Samols, E; Weir, GC | 1 |
| Pipeleers, D | 1 |
| Gerich, J; Gottesman, I; Tobert, J; Vandlen, R | 1 |
| Abdul-Karim, FW; Dahms, BB; Rodman, HM; Velasco, ME | 1 |
| Cryer, PE; Santiago, JV; White, NH | 1 |
| Beck, B; Debry, G; Kolopp, M; Toussain, P; Villaume, C | 1 |
| Dahl-Jørgensen, K; Hanssen, KF; Kriz, V; Skare, S | 1 |
| Landing, BH; Soejima, K | 1 |
| D'Onofrio, F; Lefèbvre, PJ; Paolisso, G; Passariello, N; Scheen, A; Sgambato, S | 1 |
| Efendić, S; Grill, V; Gutniak, M; Wiechel, KL | 1 |
| Bell, PM; Firth, RG; Rizza, RA | 1 |
| Adamson, U; Kollind, M; Lins, PE | 2 |
| Bolli, GB; Campbell, PJ; Gerich, JE | 1 |
| Scheen, AJ | 1 |
| Diamantopoulos, EJ; Hadjidakis, DI; Karaiskos, C; Raptis, AE; Raptis, SA; Souvatzoglou, A | 1 |
| Basdevant, A; Desplanque, N; Freychet, L; Rizkalla, SW; Slama, G; Tchobroutsky, G; Zirinis, P | 1 |
| Hilsted, J; Larsen, S; Tronier, B; Worning, H | 2 |
| Hadjidakis, DJ; Halvatsiotis, PG; Ioannou, YJ; Mavrokefalos, PJ; Raptis, SA | 1 |
| Berger, W; Keller, U; Müller, R | 1 |
| Chlup, R; Schulz, B; Woltansky, P; Wulfert, P; Zander, E | 1 |
| Broussolle, C; Martin, C; Noël, G; Orgiazzi, J; Sornay, E; Terreaux, F | 1 |
| Beylot, M; Cohen, R; Dechaud, H; Mornex, R; Riou, JP; Sautot, G; Serusclat, P | 1 |
| Cryer, PE; Gingerich, RL; Levandoski, LA; Santiago, JV; White, NH | 1 |
| Behme, MT; Chamberlain, MJ; Dupre, J; Rodger, NW | 1 |
| Abraham, G; Leiter, LA; Marliss, EB; Mitchell, TH; Schiffrin, A | 1 |
| Irjala, KM; Koskinen, PJ; Viikari, JS | 1 |
| Decsi, T; Molnár, D; Soltész, G | 1 |
| Becker, DJ; Drash, AL; Hoffman, RP; Kerensky, K; Singer-Granick, C | 1 |
| Bruining, GJ; de Beaufort, CE; den Boer, NC; Eilers, GA; van Strik, R; Weterings, T | 1 |
| Clarke, BF; Collier, DA; Kellett, HA; MacIntyre, CC; Matthews, DM; Patrick, AW; Steel, JM | 1 |
| Buch, I; Buschard, K; Hougaard, P; Kühl, C; Mølsted-Pedersen, L | 1 |
| Arany, E; Bonetto, R; del Castillo, E; Uranga, J | 1 |
| Amemiya, S; Asayama, K; Fujimoto, M; Higashida, K; Ichimura, K; Kato, K; Kusano, S; Ohyama, K | 1 |
| Khristov, V; Petkova, M; Tsanev, A; Zlateva, S | 1 |
| Bol'shakova, TD; Diuzheva, TG; Gal'perin, EI; Gitel', EP; Kuzovlev, NF | 1 |
| Fukuda, M; Ikegami, H; Kumahara, Y; Shima, K; Tahara, Y; Tanaka, A; Yamamoto, Y | 1 |
| Bottazzo, GF; Groop, L; Groop, PH; Koskimies, S; Meri, S; Miettinen, A | 1 |
| Heere, LP; Meinders, AE; Willekens, FL | 1 |
| Decsi, T; Hamar, A; Klujber, L; Molnár, D; Soltész, G | 1 |
| Boyle, PJ; Clutter, WE; Cryer, PE; Schwartz, NS; Shah, SD | 1 |
| D'Onofrio, F; Lefèbvre, PJ; Paolisso, G; Scheen, A; Sgambato, S; Torella, R; Varricchio, M | 1 |
| Munnich, A | 1 |
| Clutter, WE; Cryer, PE; Dalsky, GP; Holloszy, JO; Marker, JC; Schwartz, NS; Shah, SD; Tuttle, KR | 1 |
| Alberti, KG; Boye, N; Christensen, CK; Christiansen, JS; Hermansen, K; Mogensen, CE; Orskov, H; Schmitz, O | 1 |
| Lefebvre, PJ; Paolisso, G; Scheen, AJ; Sgambato, S; Torella, R | 1 |
| Anfossi, G; Carta, Q; De Facis, R; Emanuelli, G; Greco-Lucchina, P; Massucco, P; Mularoni, E; Trovati, M; Vitali, S | 1 |
| Faber, OK; Krarup, T; Madsbad, S; Tronier, B | 1 |
| Compton, A; Piehl, E; Rayburn, W; Sanfield, J | 1 |
| D'Onofrio, F; Paolisso, G; Passariello, N; Pizza, G; Sgambato, S; Torella, R; Varricchio, M | 1 |
| Cryer, PE; Havlin, CE; Levandoski, LA; Santiago, JV; Tordjman, KM; White, NH | 1 |
| Castillo, M; Fernández, JM; Gualda, P; Molina-Font, JA; Osuna, JI; Rubio, R | 1 |
| Bierwolf, B; Cossel, L; Krug, J; Lampeter, E; Lohmann, D; Verlohren, HJ | 1 |
| Kissebah, AH; Schectman, G | 1 |
| Davidson, MB; Harris, MD; Rosenberg, CS; Ziel, FH | 1 |
| Aman, J; Wranne, L | 1 |
| Kääpä, P; Knip, M; Viinikka, L; Ylikorkala, O | 1 |
| Hetenyi, G; Kovacevic, N; Lussier, B; Vranic, M | 1 |
| Buckell, HM; Kurtz, AB; Rao, RH; Spathis, GS; Vaughan, NJ | 1 |
| Carpentier, JL; Freychet, P; Gorden, P; Grunberger, G; Orci, L; Robert, A; van Obberghen, E | 1 |
| Betterle, C; Pedini, B; Presotto, F; Tessari, P; Tiengo, A; Valerio, A; Zanette, F | 1 |
| Bajorunas, DR; Fortner, JG; Jaspan, J; Sherwin, RS | 1 |
| Alberti, KG; Gill, GV; Hanning, I; Husband, DJ; Pernet, A | 1 |
| Gerich, JE | 1 |
| Jensen, MD; Miles, JM | 1 |
| Anderson, PG; Braund, KG; Dillon, AR; Sartin, JL | 1 |
| Akiyama, Y; Kodama, S; Matsuo, T; Ninomiya, M; Nishio, H; Takahashi, T; Takumi, T; Tsubota, T | 1 |
| Arachi, S; Fallucca, F; Fiore, R; Gargiulo, P; Maldonato, A; Pachi, A; Pimpinella, G; Tinelli, FP; Zicari, D | 1 |
| Eisenbarth, GS; Ganda, OP; Gleason, RE; Soeldner, JS; Srikanta, S | 1 |
| Fyhrquist, F; Groop, L; Groop, PH; Tötterman, KJ | 1 |
| Viberti, GC; Wiseman, MJ | 1 |
| Katsura, M | 1 |
| Castellino, P; DeFronzo, RA; Simonson, DC | 1 |
| Cherrington, AD; Cohen, RM; Frank, BH; Galloway, JA; Licinio, J; Polonsky, KS; Rubenstein, AH | 1 |
| Bezwoda, WR; Bothwell, TH; Joffe, BI; Kalk, WJ; Rumbak, MJ; Seftel, HC | 1 |
| Alberti, KG; Christensen, CK; Christiansen, JS; Hermansen, K; Mogensen, CE; Møller, A; Orskov, H; Schmitz, O | 1 |
| Biso, P; Buratti, P; Capelli, M; Melchionda, N; Pasquali, R; Pasqui, F; Patrono, D | 1 |
| Besch, W; Hahn, HJ; Klöting, I; Ziegler, B; Ziegler, M | 1 |
| Laakso, M; Pyörälä, K; Sarlund, H | 1 |
| Amiel, SA; Lauritano, AA; Sherwin, RS; Simonson, DC; Tamborlane, WV | 1 |
| Franz, MJ | 1 |
| Krarup, T; Kühl, C; Madsbad, S; Møller-Jensen, B; Sauerbrey, N | 1 |
| Rönnemaa, T | 1 |
| Bergua, M; Capillas, R; Casamitjana, R; Goday, A; Guillén, M; Gutiérrez, A; Levy, I; Recasens, A; Rodríguez, MD; Vidal, N | 1 |
| Andres, J; Maclaren, NK; Riley, WJ; Rosenbloom, AL; Toskes, PP; Winter, WE | 1 |
| Amiel, SA; DeFronzo, RA; Sherwin, RS; Simonson, DC; Tamborlane, WV | 1 |
| Bolli, GB; Cryer, PE; Gerich, JE; Go, VL; Kennedy, FP | 1 |
| Garrote, FJ; Herrera Pombo, JL; Pascual, JM; Rovira, A; Salvador, MG; Valverde, I | 1 |
| Christensen, NJ; Hilsted, J; Krarup, T; Madsbad, S; Sestoft, L; Tronier, B | 1 |
| Dimitriadis, GD; Gerich, JE; Go, VL; Tessari, P | 1 |
| Albrecht, G; Besch, W; Förster, F; Menzel, R; Pusch, H; Ratzmann, GW; Ruhnke, R | 1 |
| Chlup, R; Lubs, D; Schulz, B; Woltansky, P; Zander, E | 1 |
| Cerciello, T; Ceriello, A; D'Onofrio, F; Di Pinto, P; Giannetti, G; Giugliano, D | 1 |
| Cohen, RM; Douglas, F; Herold, KC; Levy, J; Polonsky, KS | 1 |
| DeFronzo, RA; Sherwin, RS; Simonson, DC; Tamborlane, WV | 1 |
| Cryer, PE; Hansen, IL; Rizza, RA | 1 |
| Avogaro, A; Baccaglini, U; Del Prato, S; Duner, E; Nosadini, R; Tiengo, A; Tremolada, C; Trevisan, R; Vigili de Kreutzenberg, S | 1 |
| Eisenbarth, GS; Ganda, OP; Rabizadeh, A; Soeldner, JS; Srikanta, S | 1 |
| Habich, K; Heitz, PU; Klöppel, G; Löhr, M; Oberholzer, M | 1 |
| Alberti, KG; Hanning, I; Home, PD; Jimenez, JT; Walford, S | 1 |
| Błasiak, M; Kokot, F; Kuska, J | 1 |
| Abe, H; Kawamori, R; Kikuchi, M; Shichiri, M; Yamasaki, Y | 1 |
| Iwamoto, Y; Kamata, I; Kuzuya, T; Matsuda, A; Sakamoto, Y | 1 |
| Bosi, E; Dubernard, JM; Gelet, A; Piatti, PM; Pontiroli, AE; Pozza, G; Secchi, A; Touraine, JL; Traeger, J | 1 |
| Billesbølle, P; Kølendorf, K; Poulsen, S; Thorsteinsson, B | 1 |
| Bratusch-Marrain, P; Waldhäusl, W | 1 |
| Artal, R; Romem, Y; Wiswell, R | 1 |
| House, F; Keen, H; Redmond, S; Viberti, GC; Wiseman, MJ | 1 |
| August, G; Cresto, JC; Hung, W; Lavine, RL; Perrino, P; Recant, L | 1 |
| Juhl, F; Persson, I; Svendsen, D | 1 |
| Cerasi, E; Efendic, S; Luft, R | 1 |
| Gottesbüren, H; Leising, H; Lorenz-Meyer, H; Menge, H; Riecken, EO | 1 |
| Caccamo, A; Chiumello, G; Del Guercio, MJ; Devetta, M; Di Natale, B | 1 |
| Forsham, PH; Gerich, JE; Karam, JH; Langlois, M; Noacco, C | 1 |
| Tuchinda, C | 1 |
| Faloona, GR; Müller, WA; Unger, RH | 1 |
| Barta, L; Molnár, M; Szabó, M; Tichy, MV | 1 |
| de Lange, WE; Doorenbos, H; Visser, JW | 1 |
| Heding, LG; Rasmussen, SM | 1 |
| Guthrie, RA; Jackson, RL; Lang, J; Murthy, DY | 1 |
| Drash, A | 1 |
| Jablońska, A | 1 |
| Genuth, SM | 1 |
| Neumann, B; Weber, B | 1 |
| Bergner, D; Grabner, W; Sommer, B | 1 |
| Avruskin, TW; Juan, CS; Tang, SC | 1 |
| Aguilar-Parada, E; Eisentraut, AM; Unger, RH | 1 |
| Spahn, U; Voss, E | 1 |
| Carpenter, DF; Di Sant' Agnese, P; Gorden, P; Handwerger, S; Peter, G; Roth, J | 1 |
| Aguilar-Parada, E; Faloona, GR; Müller, WA; Unger, RH | 1 |
| Aguilar-Parada, E; Eisentraut, AM; Müller, WA; Unger, RH | 1 |
| Barta, L; Molnár, M; Szabó, M; Tichy, M | 1 |
| Baumann, JB; Girard, J; Herz, G; Nars, PW; Stahl, M | 1 |
| Ackerman, E; Cremer, GM; Gatewood, LC; Molnar, GD; Moxness, KE; Rosevear, JW; Service, FJ; Taylor, WF | 1 |
| Lefebvre, P; Luyckx, A | 1 |
| Felber, JP | 1 |
| Hansen, AP; Johansen, K | 1 |
| Mégevand, A | 1 |
| Kowalski, H; Lawecki, J; Rogala, H | 1 |
| Helge, H; Quabbe, HJ; Weber, B | 1 |
| Drash, A; Sperling, M | 1 |
| Bubnova, MM; Kniazev, IuA | 1 |
| Drash, A; Field, JB; Garces, LY; Kenny, FM; Mintz, D; Vazquez, AM | 1 |
| Helge, H; Sihombing, G; Weber, B | 1 |
| Guthrie, RA; Jackson, RL; Murthy, DY; Womack, WN | 2 |
| Hagura, R; Kosaka, K; Kuzuya, T; Saito, R; Tsukamoto, F | 1 |
| Labrune, B; Mallet, R | 1 |
| Alcántara, A; Clemente, F; López-Delgado, MI; Luque, MA; Malaisse, WJ; Márquez, L; Morales, M; Puente, J; Valverde, I; Villanueva-Peñacarrillo, ML; Viñambres, C | 1 |
| Beylot, M; Chayvialle, JA; Cohen, R; Mornex, R; Rebattu, B; Riou, JP; Sautot, G | 1 |
153 review(s) available for glucagon and Autoimmune Diabetes
| Article | Year |
|---|---|
The Role of the α Cell in the Pathogenesis of Diabetes: A World beyond the Mirror.
Topics: Animals; Autocrine Communication; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Humans; Hypoglycemic Agents; Insulin-Secreting Cells; Paracrine Communication | 2021 |
New Fast Acting Glucagon for Recovery from Hypoglycemia, a Life-Threatening Situation: Nasal Powder and Injected Stable Solutions.
Topics: Administration, Intranasal; Adult; Child; Critical Care; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Insulin, Regular, Human; Powders; Sulfonylurea Compounds; Treatment Outcome | 2021 |
Targeting the Pancreatic α-Cell to Prevent Hypoglycemia in Type 1 Diabetes.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Glucagon-Secreting Cells; Humans; Hypoglycemia; Insulin; Molecular Targeted Therapy | 2021 |
Emergency Glucagon: a Focused Review of Psychosocial Experiences of Rescue Drugs for Type 1 Diabetes.
Topics: Caregivers; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents | 2022 |
Current Management of Glycemia in Children with Type 1 Diabetes Mellitus.
Topics: Blood Glucose; Blood Glucose Self-Monitoring; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Glycemic Control; Humans; Hypoglycemia; Insulin; Insulin Infusion Systems; Practice Guidelines as Topic | 2022 |
Medical devices, smart drug delivery, wearables and technology for the treatment of Diabetes Mellitus.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Insulin; Technology; Wearable Electronic Devices | 2022 |
Importance of multiple endocrine cell types in islet organoids for type 1 diabetes treatment.
Topics: Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Organoids | 2022 |
New Developments in Glucagon Treatment for Hypoglycemia.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Humans; Hypoglycemia; Insulin | 2022 |
The endocrine pancreas during exercise in people with and without type 1 diabetes: Beyond the beta-cell.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Exercise; Glucagon; Glucagon-Secreting Cells; Glucose; Humans; Insulin; Islets of Langerhans; Male | 2022 |
Clinical efficacy and safety of dasiglucagon in severe hypoglycemia associated with patients of type 1 diabetes mellitus: a systematic review and meta-analysis.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Treatment Outcome | 2023 |
Translational aspects of glucagon: current use and future prospects.
Topics: Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; Glucagon-Secreting Cells; Humans; Hypoglycemia; Insulin | 2023 |
Dasiglucagon for the Treatment of Insulin-induced Hypoglycemia in Patients with Type 1 Diabetes Mellitus: A Meta-analysis
Topics: Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin | 2023 |
Novel Preparations of Glucagon for the Prevention and Treatment of Hypoglycemia.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Exercise; Glucagon; Homeostasis; Hormones; Humans; Hypoglycemia | 2019 |
Glucagon-like peptide 1 receptor agonists in type 1 diabetes mellitus.
Topics: Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Exenatide; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucagon-Secreting Cells; Humans; Hypoglycemia; Hypoglycemic Agents; Incretins; Insulin; Liraglutide; Treatment Outcome; Weight Loss | 2019 |
Role of Glucagon in Automated Insulin Delivery.
Topics: Automation; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Glucagon; Glycemic Control; Humans; Hypoglycemia; Insulin; Insulin Infusion Systems; Pancreas, Artificial | 2020 |
Intranasal versus injectable glucagon for hypoglycemia in type 1 diabetes: systematic review and meta-analysis.
Topics: Administration, Intranasal; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Injections, Intramuscular; Injections, Subcutaneous; Insulin; Randomized Controlled Trials as Topic; Treatment Outcome | 2020 |
Evaluating dasiglucagon as a treatment option for hypoglycemia in diabetes.
Topics: Area Under Curve; Blood Glucose; Clinical Trials, Phase II as Topic; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Glucagon; Half-Life; Humans; Hypoglycemia; Hypoglycemic Agents; Male; Randomized Controlled Trials as Topic | 2020 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; 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Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus | 2016 |
Engineering biopharmaceutical formulations to improve diabetes management.
Topics: Biological Products; Blood Glucose; Diabetes Mellitus, Type 1; Drug Compounding; Glucagon; Humans; Hypoglycemic Agents; Insulin | 2021 |
Pancreatic islet reserve in type 1 diabetes.
Topics: Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Insulin Secretion; Insulin-Secreting Cells | 2021 |
SGLT2i increased the plasma fasting glucagon level in patients with diabetes: A meta-analysis.
Topics: Adolescent; Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Humans; Hypoglycemic Agents; Insulin; Ketone Bodies; Male; Middle Aged; Sodium-Glucose Transporter 2 Inhibitors; Young Adult | 2021 |
Dasiglucagon: First Approval.
Topics: Blood Glucose; Clinical Trials, Phase III as Topic; Diabetes Mellitus, Type 1; Double-Blind Method; Glucagon; Humans; Hyperinsulinism; Hypoglycemia; Injections, Subcutaneous; Randomized Controlled Trials as Topic | 2021 |
Dasiglucagon: an effective medicine for severe hypoglycemia.
Topics: Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Drug Interactions; Drug Stability; Gastric Bypass; Glucagon; Humans; Hypoglycemia; Insulin; Pancreas, Artificial; Patient Acuity | 2021 |
Dual-hormone artificial pancreas for management of type 1 diabetes: Recent progress and future directions.
Topics: Blood Glucose; Diabetes Complications; Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Insulin Infusion Systems; Islet Amyloid Polypeptide; Pancreas, Artificial | 2021 |
Mini-review: Glucagon responses in type 1 diabetes - a matter of complexity.
Topics: Animals; Anti-Inflammatory Agents; Diabetes Mellitus, Type 1; Exercise; Glucagon; Glucagon-Secreting Cells; Humans; Hypoglycemic Agents | 2021 |
A shared comparison of diabetes mellitus and neurodegenerative disorders.
Topics: Amyloid; Animals; Brain; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Humans; Insulin; Insulin-Secreting Cells; Kidney Glomerulus; Neurodegenerative Diseases | 2018 |
Glucagon, a key factor in the pathophysiology of type 2 diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fasting; Glucagon; Glucose; Humans; Hyperglycemia; Liver; Rodentia | 2017 |
Dual-hormone artificial pancreas: benefits and limitations compared with single-hormone systems.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Dietary Carbohydrates; Drug Therapy, Combination; Exercise; Glucagon; Glycated Hemoglobin; Healthy Lifestyle; Hormones; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Pancreas, Artificial; Patient Safety; Postprandial Period; Quality of Life; Randomized Controlled Trials as Topic; Treatment Outcome | 2018 |
Glucagon treatment in type 1 diabetes -with focus on restoring plasma glucose during mild hypoglycemia
.
Topics: Blood Glucose; Diabetes Complications; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin | 2018 |
Alpha cell dysfunction in type 1 diabetes.
Topics: Diabetes Mellitus, Type 1; Glucagon; Glucagon-Secreting Cells; Glucose; Humans; Insulin; Islets of Langerhans | 2018 |
Stable Liquid Glucagon: Beyond Emergency Hypoglycemia Rescue.
Topics: Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia | 2018 |
Intranasal glucagon for hypoglycaemia in diabetic patients. An old dream is becoming reality?
Topics: Adjuvants, Pharmaceutic; Administration, Intranasal; beta-Cyclodextrins; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Drug Compounding; Emergency Treatment; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Phosphorylcholine; Powders; Severity of Illness Index | 2018 |
The α-cell in diabetes mellitus.
Topics: Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Glucagon-Secreting Cells; Humans; Insulin; Insulin-Secreting Cells; Male; Role; Sensitivity and Specificity | 2018 |
Therapeutic Use of Intranasal Glucagon: Resolution of Hypoglycemia.
Topics: Administration, Intranasal; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Humans; Hypoglycemia; Risk; Treatment Outcome | 2019 |
A review of artificial pancreas technologies with an emphasis on bi-hormonal therapy.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Forecasting; Glucagon; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulins; Pancreas, Artificial | 2013 |
Treating type 1 diabetes: from strategies for insulin delivery to dual hormonal control.
Topics: Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 1; Drug Delivery Systems; Glucagon; History, 20th Century; Humans; Hypoglycemic Agents; Insulin; Insulin Infusion Systems | 2013 |
[Type LADA diabetes--interrogation points].
Topics: Autoantibodies; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Disease Progression; Glucagon; Humans; Insulin; Islets of Langerhans | 2013 |
New technologies in the treatment of type 1 diabetes.
Topics: Algorithms; Biosensing Techniques; Blood Glucose; Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 1; Drug Dosage Calculations; Glucagon; Humans; Insulin; Insulin Infusion Systems | 2013 |
Can GLP-1 preparations be used in children and adolescents with diabetes mellitus?
Topics: Adolescent; Adult; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Liraglutide; Male; Pediatric Obesity; Randomized Controlled Trials as Topic; Receptors, Glucagon | 2014 |
Metabolic phenotyping guidelines: assessing glucose homeostasis in rodent models.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Fasting; Female; Glucagon; Glucose; Glucose Tolerance Test; Guidelines as Topic; Homeostasis; Humans; Insulin; Insulin Resistance; Male; Mice; Phenotype; Pregnancy; Pregnancy in Diabetics; Rats; Somatostatin | 2014 |
Minimizing morbidity of hypoglycemia in diabetes: a review of mini-dose glucagon.
Topics: Adult; Blood Glucose; Child; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Glucagon; Humans; Hypoglycemia; Injections, Subcutaneous; Morbidity | 2015 |
[GLP-1 analogues in treatment of type 1 diabetes mellitus].
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Evidence-Based Medicine; Glucagon; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Insulin; Treatment Outcome | 2014 |
How to fight obesity with antidiabetic drugs: targeting gut or kidney?
Topics: Anti-Obesity Agents; Bariatric Surgery; Biological Transport; Clinical Trials as Topic; Comorbidity; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Exenatide; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glucose; Glycosuria; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Kidney Tubules, Proximal; Microvilli; Multicenter Studies as Topic; Obesity; Peptides; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Venoms; Weight Loss | 2015 |
Intranasal glucagon: a promising approach for treatment of severe hypoglycemia.
Topics: Administration, Intranasal; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Severity of Illness Index | 2015 |
Dual-hormone treatment with insulin and glucagon in patients with type 1 diabetes.
Topics: Diabetes Mellitus, Type 1; Drug Therapy, Combination; Glucagon; Hormone Replacement Therapy; Hormones; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Weight Gain | 2015 |
Islet α cells and glucagon--critical regulators of energy homeostasis.
Topics: Adipose Tissue; Blood Glucose; Brain; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Energy Metabolism; Glucagon; Glucagon-Secreting Cells; Homeostasis; Hormones; Humans; Hypoglycemic Agents; Insulin; Liver; Myocardium | 2015 |
Experimental and clinical aspects of melatonin and clock genes in diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Humans; Insulin; Melatonin | 2015 |
An artificial pancreas for automated blood glucose control in patients with Type 1 diabetes.
Topics: Algorithms; Blood Glucose; Blood Glucose Self-Monitoring; Clinical Trials as Topic; Computer Simulation; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Pancreas, Artificial; Quality of Life | 2015 |
Glucagon - the new 'insulin' in the pathophysiology of diabetes.
Topics: CREB-Binding Protein; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Secreting Cells; Gluconeogenesis; Histone Acetyltransferases; Humans; Insulin; Insulin-Secreting Cells; Liver; Phosphorylation; Transcription Factors | 2015 |
Exercise and the Development of the Artificial Pancreas: One of the More Difficult Series of Hurdles.
Topics: Actigraphy; Algorithms; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 1; Diffusion of Innovation; Energy Metabolism; Equipment Design; Exercise; Glucagon; Humans; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Motor Activity; Pancreas, Artificial; Predictive Value of Tests; Signal Processing, Computer-Assisted; Time Factors; Treatment Outcome | 2015 |
Glucagon therapeutics: Dawn of a new era for diabetes care.
Topics: Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Humans; Hypoglycemic Agents | 2016 |
Glucagon orchestrates stress-induced hyperglycaemia.
Topics: Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide-1 Receptor; Humans; Hyperglycemia; Stress, Physiological | 2016 |
Glucose-dependent insulinotropic polypeptide: effects on insulin and glucagon secretion in humans.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Hypoglycemia; Insulin; Insulin Secretion; Male; Randomized Controlled Trials as Topic | 2016 |
QUESTION 1: Can mini-glucagon be used to manage hypoglycaemia as an outpatient?
Topics: Blood Glucose; Child, Preschool; Diabetes Mellitus, Type 1; Female; Gastroenteritis; Glucagon; Humans; Hypoglycemia; Outpatients; Peptide Fragments | 2016 |
The role of glucagon in the artificial pancreas.
Topics: Animals; Diabetes Mellitus, Type 1; Drug Delivery Systems; Glucagon; Humans; Insulin; Pancreas, Artificial | 2016 |
Early sympathetic islet neuropathy in autoimmune diabetes: lessons learned and opportunities for investigation.
Topics: Autoimmunity; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Glucagon; Humans; Nerve Growth Factors; Sympathetic Nervous System | 2016 |
A Review of Safety and Design Requirements of the Artificial Pancreas.
Topics: Algorithms; Animals; Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Insulin Secretion; Pancreas, Artificial; Safety | 2016 |
Glucagon in artificial pancreas systems: Potential benefits and safety profile of future chronic use.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Hormones; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Pancreas, Artificial | 2017 |
Intranasal Glucagon for Severe Hypoglycemia.
Topics: Administration, Intranasal; Adolescent; Blood Glucose; Caregivers; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemia; Insulin; Male; Patient Education as Topic; Prognosis; Randomized Controlled Trials as Topic; Severity of Illness Index; Treatment Outcome | 2017 |
Assessment and management of hypoglycemia in children and adolescents with diabetes.
Topics: Adolescent; Blood Glucose; Child; Diabetes Mellitus, Type 1; Diagnosis, Differential; Eating; Exercise; Glucagon; Glycated Hemoglobin; Humans; Hypoglycemia; Infant; Insulin; Mood Disorders; Speech Disorders; Vision Disorders | 2009 |
Zinc, alpha cells and glucagon secretion.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cation Transport Proteins; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Secreting Cells; Homeostasis; Humans; Potassium Channels; Rats; Zinc | 2010 |
The perspectives of adjunctive drugs usage in the treatment of glucose metabolism disturbances in adolescent patients.
Topics: Adipose Tissue; Adolescent; Adult; Amyloid; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Islet Amyloid Polypeptide; Male; Receptors, Cannabinoid | 2009 |
Managing the adolescent athlete with type 1 diabetes mellitus.
Topics: Adolescent; Athletes; Carbohydrates; Child; Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Insulin; Practice Guidelines as Topic; Risk Assessment; Sports Medicine | 2010 |
The physiology of glucagon.
Topics: Animals; Autonomic Nervous System; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Glucagon-Secreting Cells; Glycogen; Homeostasis; Humans; Hypoglycemia; Insulin; Islets of Langerhans; Liver | 2010 |
Optimizing reduction in basal hyperglucagonaemia to repair defective glucagon counterregulation in insulin deficiency.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Secreting Cells; Hypoglycemia; Insulin; Insulin-Secreting Cells; Postprandial Period | 2011 |
Minireview: Glucagon in the pathogenesis of hypoglycemia and hyperglycemia in diabetes.
Topics: Animals; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Secreting Cells; Humans; Hyperglycemia; Hypoglycemia; Insulin; Mice; Models, Biological; Rats; Somatostatin | 2012 |
Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover.
Topics: Animals; Diabetes Mellitus, Type 1; Glucagon; Glycogenolysis; Humans; Insulin; Liver; Mice; Pancreas | 2012 |
Safe glycemic management during closed-loop treatment of type 1 diabetes: the role of glucagon, use of multiple sensors, and compensation for stress hyperglycemia.
Topics: Algorithms; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Pancreas, Artificial; Stress, Psychological | 2011 |
Minireview: The role of the autonomic nervous system in mediating the glucagon response to hypoglycemia.
Topics: Animals; Autoimmunity; Autonomic Nervous System; Central Nervous System; Diabetes Mellitus; Diabetes Mellitus, Type 1; Gene Expression Regulation; Glucagon; Glucose; Humans; Hypoglycemia; Insulin Resistance; Islets of Langerhans; Models, Biological; Peripheral Nervous System | 2012 |
Stable liquid glucagon formulations for rescue treatment and bi-hormonal closed-loop pancreas.
Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Injections, Subcutaneous; Insulin Infusion Systems; Models, Biological; Pancreas, Artificial; Reproducibility of Results; Swine | 2012 |
Contrasting effects of type 2 and type 1 diabetes on plasma RBP4 levels: the significance of transthyretin.
Topics: Biomarkers; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Gene Expression Regulation; Glomerular Filtration Rate; Glucagon; Humans; Insulin; Pancreas; Prealbumin; Protein Multimerization; Protein Structure, Quaternary; Retinol-Binding Proteins, Plasma; Signal Transduction; Vitamin A | 2012 |
Dysglycaemia in the critically ill - significance and management.
Topics: Analysis of Variance; Biomarkers; Blood Glucose; Critical Illness; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Female; Glucagon; Glucagon-Like Peptide 1; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Risk Factors | 2013 |
Hypoglycaemia: the limiting factor in the glycaemic management of Type I and Type II diabetes.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Epinephrine; Glucagon; Humans; Hypoglycemia; Insulin | 2002 |
[Glucagon test].
Topics: Diabetes Mellitus, Type 1; Diagnosis, Differential; Glucagon; Humans; Insulin; Insulin Secretion; Islets of Langerhans | 2002 |
[Regenerative medicine in diabetes by beta cell therapy and promotion of beta cell growth and differentiation].
Topics: Animals; Antigens, Neoplasm; Betacellulin; Biomarkers, Tumor; Cell Differentiation; Cell Division; Diabetes Mellitus, Type 1; Genetic Therapy; Glucagon; Glucagon-Like Peptide 1; Humans; Intercellular Signaling Peptides and Proteins; Islets of Langerhans; Islets of Langerhans Transplantation; Lectins, C-Type; Niacinamide; Pancreatitis-Associated Proteins; Peptide Fragments; Protein Precursors; Proteins; Regeneration; Stem Cell Transplantation; Stem Cells; Tissue Engineering | 2002 |
Novel peptides under development for the treatment of type 1 and type 2 diabetes mellitus.
Topics: Amyloid; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Drug Design; Exenatide; Glucagon; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Islet Amyloid Polypeptide; Peptide Fragments; Peptides; Postprandial Period; Protein Precursors; Venoms | 2002 |
Autonomic mechanism and defects in the glucagon response to insulin-induced hypoglycaemia.
Topics: Animals; Autonomic Nervous System; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Insulin; Islets of Langerhans | 2002 |
[MORPHOLOGICAL PROBLEMS IN DIABETES RESEARCH].
Topics: Adolescent; Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucagon; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Islands; Islets of Langerhans; Obesity; Pathology; Research | 1964 |
Emerging therapies: controlling glucose homeostasis, immunotherapy, islet transplantation, gene therapy, and islet cell neogenesis and regeneration.
Topics: Blood Glucose; Cell Differentiation; Cell Division; Diabetes Mellitus, Type 1; Exenatide; Genetic Therapy; Glucagon; Glucagon-Like Peptide 1; Homeostasis; Humans; Immunotherapy; Islets of Langerhans; Islets of Langerhans Transplantation; Peptide Fragments; Peptides; Protein Precursors; Stem Cells; Venoms | 2004 |
Glucagon-like peptide 1 agonists and the development and growth of pancreatic beta-cells.
Topics: Animals; Cell Division; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Humans; Islets of Langerhans; Islets of Langerhans Transplantation; Peptide Fragments; Protein Precursors | 2004 |
Glucagon-like peptide 1: evolution of an incretin into a treatment for diabetes.
Topics: Animals; Diabetes Mellitus, Type 1; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin; Peptide Fragments; Protein Precursors | 2004 |
Pramlintide for the treatment of insulin-requiring diabetes mellitus: rationale and review of clinical data.
Topics: Amyloid; Animals; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Glucagon; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Insulin; Islet Amyloid Polypeptide; Peptide Fragments; Protein Precursors | 2004 |
Markers of beta cell function in type 1 diabetes mellitus.
Topics: Age Factors; Autoantibodies; Biomarkers; C-Peptide; Cell Death; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Diabetic Retinopathy; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Islets of Langerhans | 2004 |
Glycaemic effects of incretins in Type 1 diabetes mellitus: a concise review, with emphasis on studies in humans.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Food; Glucagon; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Peptide Fragments; Protein Precursors; Time Factors | 2005 |
Weight effect of current and experimental drugs for diabetes mellitus: from promotion to alleviation of obesity.
Topics: Amyloid; Benzamides; Biguanides; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Insulin; Islet Amyloid Polypeptide; Obesity; Peptide Fragments; Protein Precursors; Sulfonylurea Compounds; Thiazolidinediones; Weight Gain | 2003 |
Pramlintide in the treatment of type 1 and type 2 diabetes mellitus.
Topics: Amyloid; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Drug Interactions; Drug Therapy, Combination; Glucagon; Humans; Hypoglycemic Agents; Insulin; Islet Amyloid Polypeptide; Postprandial Period | 2005 |
Applications of dipeptidyl peptidase IV inhibitors in diabetes mellitus.
Topics: Amino Acid Sequence; Animals; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Humans; Molecular Sequence Data; Peptide Fragments; Protease Inhibitors | 2006 |
Pramlintide: A new tool in diabetes management.
Topics: Amyloid; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Gastric Emptying; Glucagon; Humans; Hypoglycemic Agents; Islet Amyloid Polypeptide; Models, Biological; Pancreas | 2006 |
New treatments of diabetes: the beta-amylin agonists.
Topics: Amyloid; Animals; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Eating; Glucagon; Humans; Hypoglycemic Agents; Insulin; Islet Amyloid Polypeptide | 2008 |
[Hypoglycemia as a limiting factor in the management of type 1 diabetes].
Topics: Accidents, Traffic; Adolescent; Adult; Aged; Autonomic Nervous System Diseases; Blood Glucose Self-Monitoring; Brain Injuries; Child; Child, Preschool; Diabetes Mellitus, Type 1; Gastrointestinal Agents; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Secretion; Middle Aged; Young Adult | 2008 |
[Current aspects of the etiopathogenesis of diabetes mellitus].
Topics: Carbohydrates; Cushing Syndrome; Diabetes Mellitus; Diabetes Mellitus, Type 1; Endocrine System Diseases; Glucagon; HLA Antigens; Humans; Insulin; Islets of Langerhans; Liver Cirrhosis; Paraneoplastic Endocrine Syndromes; Somatostatin; Virus Diseases | 1981 |
Coordinated responses of glucogenic hormones to central glucopenia: the role of the sympathoadrenal system.
Topics: Adrenal Glands; Animals; Diabetes Mellitus, Type 1; Epinephrine; Feedback; Glucagon; Gluconeogenesis; Glucose; Hormones; Humans; Hypoglycemia; Kinetics | 1983 |
Physiological effects of exercise in the diabetic.
Topics: Blood Glucose; Catecholamines; Diabetes Mellitus, Type 1; Exercise Therapy; Fatty Acids, Nonesterified; Glucagon; Gluconeogenesis; Growth Hormone; Humans; Hydrocortisone; Insulin; Physical Exertion | 1984 |
Islet function and stress hyperglycemia: plasma glucose and epinephrine interaction.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Epinephrine; Feedback; Glucagon; Humans; Hyperglycemia; Hypoxia; Insulin; Insulin Secretion; Islets of Langerhans; Myocardial Infarction; Physical Exertion; Stress, Physiological; Surgical Procedures, Operative; Sympathetic Nervous System; Wounds and Injuries | 1984 |
C-peptide and free insulin determinations in type I diabetes; relationships with metabolic control and insulin therapy.
Topics: C-Peptide; Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Islets of Langerhans | 1984 |
On the pathogenesis of the increased glomerular filtration rate in short-term insulin-dependent diabetes.
Topics: Adult; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Female; Glomerular Filtration Rate; Glucagon; Growth Hormone; Humans; Insulin; Kidney; Male; Rats; Renal Circulation; Time Factors | 1984 |
Metabolic adjustments in normal and diabetic pregnancy.
Topics: Adipose Tissue; Animals; Body Weight; Congenital Abnormalities; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Humans; Insulin; Insulin Secretion; Ketone Bodies; Lipid Metabolism; Lipoproteins; Maternal-Fetal Exchange; Pregnancy; Pregnancy in Diabetics | 1981 |
C-peptide measurement and its clinical usefulness: a review.
Topics: Adolescent; Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemia; Infant, Newborn; Insulin; Insulinoma; Islets of Langerhans; Kidney Function Tests; Middle Aged; Peptides; Radioimmunoassay | 1981 |
Hypoglycaemia unawareness.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Epinephrine; Glucagon; Humans; Hypoglycemia; Insulin | 1994 |
The incretin notion and its relevance to diabetes.
Topics: Amino Acid Sequence; Animals; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose; Humans; Insulin; Insulin Secretion; Molecular Sequence Data; Peptide Fragments; Protein Precursors | 1993 |
Nocturnal blood glucose control in type I diabetes mellitus.
Topics: Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Drug Administration Schedule; Epinephrine; Fasting; Glucagon; Growth Hormone; Homeostasis; Humans; Hydrocortisone; Insulin; Norepinephrine; Reference Values | 1993 |
Epinephrine secretion, hypoglycemia unawareness, and diabetic autonomic neuropathy.
Topics: Autonomic Nervous System Diseases; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Epinephrine; Glucagon; Humans; Hypoglycemia; Risk Factors | 1994 |
Tumour-induced hypoglycaemia in a patient with insulin-dependent diabetes mellitus.
Topics: Adult; Amyloid; Diabetes Mellitus, Type 1; Diagnosis, Differential; Fatal Outcome; Female; Glucagon; Humans; Hypoglycemia; Insulin; Insulinoma; Islet Amyloid Polypeptide; Pancreatic Neoplasms | 1996 |
The role of prohormone convertases in insulin biosynthesis: evidence for inherited defects in their action in man and experimental animals.
Topics: Animals; Aspartic Acid Endopeptidases; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Humans; Insulin; Islets of Langerhans; Obesity; Organ Specificity; Proinsulin; Proprotein Convertase 2; Proprotein Convertases; Subtilisins | 1996 |
Modulation of gastric emptying as a therapeutic approach to glycaemic control.
Topics: Amino Acid Sequence; Amyloid; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Gastric Emptying; Glucagon; Humans; Hyperglycemia; Islet Amyloid Polypeptide; Molecular Sequence Data; Postprandial Period; Rats | 1996 |
Assessment of residual insulin secretion in diabetic patients using the intravenous glucagon stimulatory test: methodological aspects and clinical applications.
Topics: Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion | 1996 |
On the effects of glucagon-like peptide-1 on blood glucose regulation in normal and diabetic subjects.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Digestive System; Digestive System Physiological Phenomena; Glucagon; Glucagon-Like Peptide 1; Homeostasis; Humans; Islets of Langerhans; Peptide Fragments; Proglucagon; Protein Precursors; Protein Processing, Post-Translational; Reference Values | 1996 |
Hierarchy of physiological responses to hypoglycemia: relevance to clinical hypoglycemia in type I (insulin dependent) diabetes mellitus.
Topics: Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Humans; Hypoglycemia; Insulin; Perception | 1997 |
Renal glucose production and utilization: new aspects in humans.
Topics: Animals; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Gluconeogenesis; Glucose; Glycerol; Humans; Insulin; Kidney; Lactates | 1997 |
Glucagon-like peptides.
Topics: Amino Acid Sequence; Animals; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Humans; Molecular Sequence Data; Peptide Fragments; Peptides; Protein Precursors; Receptors, Glucagon | 1998 |
Autonomic mediation of glucagon secretion during hypoglycemia: implications for impaired alpha-cell responses in type 1 diabetes.
Topics: Animals; Autonomic Nervous System; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Insulin; Islets of Langerhans | 1998 |
Glucagon-like peptide 1 (GLP-1): a potent gut hormone with a possible therapeutic perspective.
Topics: Animals; Cerebral Ventricles; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Feeding Behavior; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glucose; Humans; Insulin; Models, Biological; Peptide Fragments; Proinsulin; Protein Precursors | 1998 |
Porcine neonatal pancreatic cell clusters (NPCCs): a potential source of tissue for islet transplantation.
Topics: Animals; Animals, Newborn; Diabetes Mellitus, Type 1; Fetal Tissue Transplantation; Glucagon; Humans; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Keratins; Mice; Mice, Nude; Pancreatic Polypeptide; Somatostatin; Swine; Transplantation, Heterologous | 1997 |
The role of insulin and other hormones in the regulation of amino acid and protein metabolism in humans.
Topics: Amino Acids; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Epinephrine; Glucagon; Gonadal Steroid Hormones; Growth Hormone; Humans; Hypoglycemic Agents; Insulin; Insulin-Like Growth Factor I; Male; Muscle, Skeletal; Proteins; Receptor, IGF Type 1; Thyroid Hormones | 1998 |
Effect of pancreatic transplantation on counterregulatory hormonal responses to hypoglycaemia.
Topics: Animals; Catecholamines; Diabetes Mellitus, Type 1; Glucagon; Homeostasis; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Hypoglycemic Agents; Insulin; Pancreas Transplantation | 1999 |
Hypoglycaemia awareness and counter-regulation in type 1 diabetes.
Topics: Awareness; Cognition; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin | 2000 |
The need for hypoglycemia detection and prevention in type 1 diabetes.
Topics: Biomarkers; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Laboratories, Hospital; Reproducibility of Results | 2001 |
[Postprandial hyperglycemia. II. Pharmacological approaches].
Topics: alpha-Glucosidases; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Enzyme Inhibitors; Glucagon; Glycoside Hydrolase Inhibitors; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Intestinal Absorption; Postprandial Period | 2002 |
[Pathophysiology and current therapy of the ketoacidotic diabetic coma].
Topics: Buffers; Dehydration; Diabetes Mellitus, Type 1; Diabetic Coma; Diabetic Ketoacidosis; Glomerular Filtration Rate; Glucagon; Glucose; Hospitalization; Humans; Infusions, Parenteral; Insulin; Insulin Secretion; Potassium | 1979 |
Present concepts in diabetology.
Topics: Adult; Blood Glucose; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diet Therapy; Female; Glucagon; Histocompatibility Antigens; Humans; Insulin; Male; Virus Diseases | 1979 |
Glucagon and diabetes.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Glucagon; Humans; Molecular Weight; Streptozocin | 1977 |
The role of glucagon in the endogenous hyperglycemia of diabetes mellitus.
Topics: Animals; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Rats; Somatostatin | 1977 |
Role of glucagon in the pathogenesis of diabetes: the status of the controversy.
Topics: Alanine; Animals; Antigens; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Dietary Proteins; Dogs; Glucagon; Glucose; Humans; Hydroxybutyrates; Hyperglycemia; Insulin; Islets of Langerhans; Ketone Bodies; Lactates; Liver; Models, Biological; Somatostatin | 1978 |
The brain as an endocrine organ.
Topics: Animals; beta-Lipotropin; Brain; Brain Chemistry; Diabetes Mellitus, Type 1; Digestive System; Endocrine Glands; Endorphins; Glucagon; Humans; Hypothalamo-Hypophyseal System; Hypothalamus; Insulin; Insulin Secretion; Peptides; Pituitary Gland, Anterior; Rats; Somatostatin; Thyrotropin | 1978 |
Somatostatin and the endocrine pancreas.
Topics: Carbohydrate Metabolism; Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Somatostatin | 1979 |
[New viewpoints on the pathogenesis of diabetes mellitus].
Topics: Autoimmune Diseases; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; HLA Antigens; Humans; Insulin Antibodies; Measles; Receptor, Insulin; Somatostatin; Virus Diseases | 1978 |
Early functional and morphologic vascular renal consequences of the diabetic state.
Topics: Albuminuria; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Nephropathies; Glomerular Filtration Rate; Glucagon; Humans; Insulin; Kidney | 1979 |
Glucagon: secretion and actions.
Topics: Animals; Animals, Newborn; Child; Diabetes Mellitus, Type 1; Dogs; Glucagon; Glucose; Glucose Tolerance Test; Humans; Infant, Newborn; Insulin; Islets of Langerhans | 1979 |
[Somatostatin. Hormone of the nervous system and of the gastrointestinal tract with multiple effects].
Topics: Diabetes Mellitus, Type 1; Glucagon; Humans; Hypothalamus; Intestinal Absorption; Pancreas; Peptic Ulcer Hemorrhage; Somatostatin | 1979 |
Dilemmas in diabetes.
Topics: Adolescent; Adult; Animals; Arteriosclerosis; Blood Glucose; Cell Membrane; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Freeze Fracturing; Glucagon; Humans; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Microscopy, Electron | 1975 |
The Banting Memorial Lecture 1975. Diabetes and the alpha cell.
Topics: Adult; Animals; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Digestive System; Glucagon; Glucose; Humans; Islets of Langerhans; Pancreas; Pancreatectomy | 1976 |
Etiologic, pathophysiologic and clinical interrelationships in diabetes.
Topics: Animals; Autoimmune Diseases; Coxsackievirus Infections; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Glucagon; Glucose; Humans; Insulin; Insulin Antibodies; Insulin Secretion; Islets of Langerhans; Pancreas Transplantation; Proinsulin; Rats; Receptors, Drug; Transplantation, Homologous | 1975 |
Octreotide and diabetes: theoretical and experimental aspects.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Growth Hormone; Humans; Insulin Resistance; Insulin-Like Growth Factor I; Octreotide; Vascular Diseases | 1992 |
The insulin-antagonistic effect of the counterregulatory hormones.
Topics: Animals; Catecholamines; Diabetes Mellitus, Type 1; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin Resistance; Reference Values; Stress, Physiological | 1991 |
Importance of glucagon for nitrogen loss in diabetes--via an accelerated hepatic conversion of amino nitrogen to urea nitrogen.
Topics: Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucagon; Humans; Liver; Nitrogen; Urea | 1991 |
Intranasal administration of peptide hormones: factors affecting transmucosal absorption.
Topics: Administration, Intranasal; Corticotropin-Releasing Hormone; Diabetes Mellitus, Type 1; Glucagon; Growth Hormone-Releasing Hormone; Hormones; Humans; Insulin; Peptides | 1990 |
[Regulation of glucose metabolism during exercise and after exercise in normal and diabetic subjects].
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Exercise; Glucagon; Glucose; Glycogen; Hormones; Humans; Insulin; Muscles; Time Factors | 1990 |
Experimental reduction of B-cell mass: implications for the pathogenesis of diabetes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Arginine; Blood Glucose; Cyclic AMP; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Drug Synergism; Glucagon; Glucose; Glucose Tolerance Test; Histocytochemistry; Humans; Immunologic Techniques; In Vitro Techniques; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Pancreatectomy; Rats; Rats, Inbred Strains | 1986 |
[Glomerular hyperfiltration during sugar diabetes].
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Glucagon; Glucose; Growth Hormone; Humans; Insulin; Kidney Glomerulus; Rats | 1985 |
[Pulsatory secretion of pancreatic hormones].
Topics: Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Humans; Insulin; Insulin Secretion; Time Factors | 1989 |
Glucose counterregulation, hypoglycemia, and intensive insulin therapy in diabetes mellitus.
Topics: Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Epinephrine; Glucagon; Glucose; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Hypoglycemia; Insulin; Islets of Langerhans; Liver; Neurotransmitter Agents | 1985 |
Intra-islet insulin-glucagon-somatostatin relationships.
Topics: Animals; Autonomic Nervous System; Cell Communication; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Humans; Insulin; Intercellular Junctions; Islets of Langerhans; Pancreatic Polypeptide; Rats; Somatostatin | 1986 |
Purified islet cells in diabetes research.
Topics: Alloxan; Animals; Antigens, Surface; Cell Separation; Cells, Cultured; Cyclic AMP; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Flavin-Adenine Dinucleotide; Flow Cytometry; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; NADP; Somatostatin; Streptozocin | 1986 |
The relevance of glucose counterregulatory systems to patients with insulin-dependent diabetes mellitus.
Topics: Adrenergic beta-Antagonists; Autonomic Nervous System Diseases; Blood Glucose; Brain; Chromaffin System; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Diabetic Neuropathies; Epinephrine; Forecasting; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Hypoglycemia; Insulin; Stress, Physiological; Sympathetic Nervous System | 1986 |
Glomerular hyperfiltration in diabetes mellitus.
Topics: Diabetes Mellitus, Type 1; Diabetic Nephropathies; Glomerular Filtration Rate; Glucagon; Growth Hormone; Humans; Hypertrophy; Insulin; Kidney | 1985 |
Hormones and lipoprotein metabolism.
Topics: Catecholamines; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Glucocorticoids; Gonadal Steroid Hormones; Growth Hormone; Hormones; Humans; Hyperinsulinism; Insulin; Lipoproteins; Menopause; Obesity; Thyroxine | 1987 |
Insulin-dependent diabetes mellitus: pathophysiology.
Topics: Autoimmune Diseases; Blood Glucose; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Diagnosis, Differential; Glucagon; Humans; Insulin; Insulin Resistance | 1986 |
Complications of insulin-dependent diabetes mellitus: management of insulin reactions and acute illness.
Topics: Acute Disease; Blood Glucose; Catecholamines; Diabetes Mellitus, Type 1; Diet, Diabetic; Dietary Carbohydrates; Eating; Glucagon; Gluconeogenesis; Humans; Hypoglycemia; Insulin; Patient Education as Topic; Self Care | 1986 |
The kidney in diabetes: significance of the early abnormalities.
Topics: Albuminuria; Blood Glucose; Blood Pressure; Diabetes Complications; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Dietary Proteins; Glomerular Filtration Rate; Glucagon; Growth Hormone; Hemodynamics; Humans; Hypertrophy; Insulin; Kidney; Prognosis; Proteinuria; Regional Blood Flow; Ultrafiltration | 1986 |
Islet pathology and the pathogenesis of type 1 and type 2 diabetes mellitus revisited.
Topics: Autoimmune Diseases; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Humans; Insulin; Islets of Langerhans | 1985 |
Current concepts of diabetes mellitus in childhood: a review.
Topics: Abnormalities, Multiple; Child; Diabetes Mellitus, Type 1; Diet, Diabetic; Female; Glucagon; Glucose Tolerance Test; Glycosuria; Humans; Hypoglycemia; Hypogonadism; Infant, Newborn; Infant, Newborn, Diseases; Insulin; Intellectual Disability; Male; Obesity; Prediabetic State; Respiratory Distress Syndrome, Newborn | 1974 |
[Free fatty acids in the serum--regulatory mechanism and clinical significance].
Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Diabetes Mellitus; Diabetes Mellitus, Type 1; Dietary Fats; Fatty Acids, Nonesterified; Female; Glucagon; Hepatitis A; Humans; Hyperthyroidism; Insulin; Lipid Metabolism; Lipid Metabolism, Inborn Errors; Male; Norepinephrine; Obesity; Physical Exertion; Prednisone; Pregnancy; Rats; Triglycerides | 1969 |
Pancreatic alpha cell function in man.
Topics: Adult; Antibodies; Arginine; Diabetes Mellitus; Diabetes Mellitus, Type 1; Fasting; Glucagon; Glucose; Humans; Islets of Langerhans; Radioimmunoassay | 1971 |
202 trial(s) available for glucagon and Autoimmune Diabetes
| Article | Year |
|---|---|
SGLT2 Inhibition Increases Fasting Glucagon but Does Not Restore the Counterregulatory Hormone Response to Hypoglycemia in Participants With Type 1 Diabetes.
Topics: Adult; Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus, Type 1; Double-Blind Method; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Clamp Technique; Glucosides; Glycemic Control; Humans; Hypoglycemia; Insulin; Male; Middle Aged; Sodium-Glucose Transporter 2 Inhibitors | 2022 |
Home Use of Mini-Dose Glucagon As a Novel Treatment for Hypoglycemia Following Repeated, Prolonged Fasts in Type 1 Diabetes During Ramadan.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Fasting; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin | 2022 |
Efficacy, safety, tolerability, and noninferiority phase 3 study of glucagon as a ready-to-use room temperature liquid stable formulation versus a lyophilised formulation for the biochemical recovery and symptomatic relief of insulin-induced severe hypogl
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Temperature | 2022 |
Low-Dose Dasiglucagon Versus Oral Glucose for Prevention of Insulin-Induced Hypoglycemia in People With Type 1 Diabetes: A Phase 2, Randomized, Three-Arm Crossover Study.
Topics: Adult; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin | 2022 |
Glucagon receptor antagonist volagidemab in type 1 diabetes: a 12-week, randomized, double-blind, phase 2 trial.
Topics: Adult; Antibodies, Monoclonal, Humanized; Blood Glucose; Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 1; Double-Blind Method; Glucagon; Glycated Hemoglobin; Humans; Insulin; Lipoproteins, LDL; Receptors, Glucagon; Transaminases; Treatment Outcome | 2022 |
A randomized trial of oral gamma aminobutyric acid (GABA) or the combination of GABA with glutamic acid decarboxylase (GAD) on pancreatic islet endocrine function in children with newly diagnosed type 1 diabetes.
Topics: Animals; Diabetes Mellitus, Type 1; gamma-Aminobutyric Acid; Glucagon; Glutamate Decarboxylase; Islets of Langerhans | 2022 |
Study protocol: a randomised controlled proof-of-concept real-world study - does maximising time in range using hybrid closed loop insulin delivery and a low carbohydrate diet restore the glucagon response to hypoglycaemia in adults with type 1 diabetes?
Topics: Adult; Blood Glucose; Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 1; Diet, Carbohydrate-Restricted; Glucagon; Glycerol; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Randomized Controlled Trials as Topic | 2022 |
Effect of Mini-Dose Ready-to-Use Liquid Glucagon on Preventing Exercise-Associated Hypoglycemia in Adults With Type 1 Diabetes.
Topics: Adult; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Exercise; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Infusion Systems | 2023 |
Effect of Isocaloric Meals on Postprandial Glycemic and Metabolic Markers in Type 1 Diabetes-A Randomized Crossover Trial.
Topics: Adult; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Dietary Fats; Glucagon; Humans; Insulin; Meals; Postprandial Period | 2023 |
Nasal glucagon as a viable alternative for treating insulin-induced hypoglycaemia in Japanese patients with type 1 or type 2 diabetes: A phase 3 randomized crossover study.
Topics: Adult; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Japan; Male | 2020 |
Evaluation of a new training program to reassure primary school teachers about glucagon injection in children with type 1 diabetes during the 2017-2018 school year.
Topics: Adult; Child; Diabetes Mellitus, Type 1; Female; France; Glucagon; Health Knowledge, Attitudes, Practice; Hormones; Humans; Hypoglycemia; Injections; Male; Middle Aged; Prospective Studies; School Teachers; Self Efficacy; Video Recording | 2020 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus | 2016 |
The effect of preceding glucose decline rate on low-dose glucagon efficacy in individuals with type 1 diabetes: A randomized crossover trial.
Topics: Adult; Blood Glucose; Blood Glucose Self-Monitoring; Cross-Over Studies; Diabetes Mellitus, Type 1; Double-Blind Method; Glucagon; Glucose; Humans; Hypoglycemic Agents; Insulin; Single-Blind Method | 2021 |
Glucagonostatic Potency of GLP-1 in Patients With Type 2 Diabetes, Patients With Type 1 Diabetes, and Healthy Control Subjects.
Topics: Blood Glucose; Denmark; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Fasting; Female; Glucagon; Glucagon-Like Peptide 1; Glucose Clamp Technique; Glycated Hemoglobin; Healthy Volunteers; Humans; Male; Middle Aged; Treatment Outcome | 2021 |
Dasiglucagon, a next-generation ready-to-use glucagon analog, for treatment of severe hypoglycemia in children and adolescents with type 1 diabetes: Results of a phase 3, randomized controlled trial.
Topics: Adolescent; Blood Glucose; Child; Diabetes Mellitus, Type 1; Double-Blind Method; Female; Germany; Glucagon; Humans; Hypoglycemia; Injections, Subcutaneous; Insulin; Male; Patient Acuity; Slovenia; Treatment Outcome; United States | 2021 |
Pancreatic β-Cell Function Is Associated with Augmented Counterregulation to In-Exercise Hypoglycemia in Type 1 Diabetes.
Topics: Adult; Biomarkers; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 1; Exercise; Female; Glucagon; Humans; Hypoglycemia; Insulin-Secreting Cells; Male; Middle Aged; Young Adult | 2021 |
Dasiglucagon, a next-generation glucagon analogue, for treatment of severe hypoglycaemia via an autoinjector device: Results of a phase 3, randomized, double-blind trial.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Double-Blind Method; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents | 2021 |
Immunogenicity of the Novel Glucagon Analogue Dasiglucagon: Results of a Dedicated Immunogenicity Trial in Type 1 Diabetes.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Double-Blind Method; Glucagon; Humans; Hypoglycemia | 2021 |
Effects of Dietary Fat and Protein on Glucoregulatory Hormones in Adolescents and Young Adults With Type 1 Diabetes.
Topics: Adult; Australia; Biomarkers; Blood Glucose; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 1; Dietary Fats; Dietary Proteins; Female; Follow-Up Studies; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Insulin; Male; Meals; Prognosis | 2022 |
A 10-second sprint does not blunt hormonal counter-regulation to subsequent hypoglycaemia.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Humans; Hypoglycemia; Insulin; Male; Norepinephrine; Running; Young Adult | 2017 |
Efficacy and Safety of Mini-Dose Glucagon for Treatment of Nonsevere Hypoglycemia in Adults With Type 1 Diabetes.
Topics: Adult; Blood Glucose; Blood Glucose Self-Monitoring; Cross-Over Studies; Diabetes Mellitus, Type 1; Female; Glucagon; Hormones; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Male; Middle Aged; Severity of Illness Index | 2017 |
Glucagon Decreases IGF-1 Bioactivity in Humans, Independently of Insulin, by Modulating Its Binding Proteins.
Topics: Adult; Blotting, Western; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Enzyme-Linked Immunosorbent Assay; Female; Forkhead Box Protein O1; Glucagon; Growth Hormone; Humans; Injections, Intramuscular; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Male; Obesity; Statistics, Nonparametric | 2017 |
The effects of add-on exenatide to insulin on glycemic variability and hypoglycemia in patients with type 1 diabetes mellitus.
Topics: Adolescent; Adult; Biomarkers; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Exenatide; Female; Follow-Up Studies; Glucagon; Glycated Hemoglobin; Glycemic Index; Humans; Hypoglycemia; Hypoglycemic Agents; Incidence; Insulin; Male; Middle Aged; Peptides; Prognosis; Venoms; Young Adult | 2018 |
Pramlintide but Not Liraglutide Suppresses Meal-Stimulated Glucagon Responses in Type 1 Diabetes.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Islet Amyloid Polypeptide; Liraglutide; Male; Meals; Postprandial Period; Treatment Outcome; Young Adult | 2018 |
Pharmacokinetic and Pharmacodynamic Characteristics of Dasiglucagon, a Novel Soluble and Stable Glucagon Analog.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glucagon; Half-Life; Humans; Hypoglycemia; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Male; Young Adult | 2018 |
Overnight Glucose Control with Dual- and Single-Hormone Artificial Pancreas in Type 1 Diabetes with Hypoglycemia Unawareness: A Randomized Controlled Trial.
Topics: Adult; Aged; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Male; Middle Aged; Pancreas, Artificial; Treatment Outcome; Young Adult | 2018 |
Impact of erroneous meal insulin bolus with dual-hormone artificial pancreas using a simplified bolus strategy - A randomized controlled trial.
Topics: Adult; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Male; Middle Aged; Pancreas, Artificial; Postprandial Period | 2018 |
Prospective study evaluating the use of nasal glucagon for the treatment of moderate to severe hypoglycaemia in adults with type 1 diabetes in a real-world setting.
Topics: Administration, Intranasal; Adult; Blood Glucose; Blood Glucose Self-Monitoring; Caregivers; Diabetes Mellitus, Type 1; Female; Glucagon; Health Knowledge, Attitudes, Practice; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Lost to Follow-Up; Male; Middle Aged; Patient Dropouts; Patient Education as Topic; Self Report; Severity of Illness Index; Syncope; Time Factors | 2018 |
A phase 3 multicenter, open-label, prospective study designed to evaluate the effectiveness and ease of use of nasal glucagon in the treatment of moderate and severe hypoglycemia in children and adolescents with type 1 diabetes in the home or school setti
Topics: Administration, Intranasal; Adolescent; Caregivers; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Hormones; Humans; Hypoglycemia; Insulin; Male; Prospective Studies; Treatment Outcome | 2018 |
Randomized Outpatient Trial of Single- and Dual-Hormone Closed-Loop Systems That Adapt to Exercise Using Wearable Sensors.
Topics: Adult; Blood Glucose; Blood Glucose Self-Monitoring; Cross-Over Studies; Diabetes Mellitus, Type 1; Exercise; Female; Glucagon; Humans; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Male; Meals; Middle Aged; Outpatients; Pancreas, Artificial; Wearable Electronic Devices; Young Adult | 2018 |
Mini-Dose Glucagon as a Novel Approach to Prevent Exercise-Induced Hypoglycemia in Type 1 Diabetes.
Topics: Adult; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Exercise; Fasting; Female; Glucagon; Glucose; Humans; Hypoglycemia; Insulin; Insulin Infusion Systems; Male | 2018 |
Low doses of dasiglucagon consistently increase plasma glucose levels from hypoglycaemia and euglycaemia in people with type 1 diabetes mellitus.
Topics: Adolescent; Adult; Area Under Curve; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glucagon; Humans; Hypoglycemia; Injections, Subcutaneous; Insulin; Insulin Infusion Systems; Male; Middle Aged; Pancreas, Artificial; Young Adult | 2019 |
Acute metabolic effects of exenatide in patients with type 1 diabetes with and without residual insulin to oral and intravenous glucose challenges.
Topics: Administration, Intravenous; Administration, Oral; Adolescent; Adult; Diabetes Mellitus, Type 1; Exenatide; Female; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Male; Middle Aged; Peptides; Venoms; Young Adult | 2014 |
The impact of insulin-independent, glucagon-induced suppression of total ghrelin on satiety in obesity and type 1 diabetes mellitus.
Topics: Adult; Diabetes Mellitus, Type 1; Double-Blind Method; Female; Ghrelin; Glucagon; Humans; Male; Obesity; Satiation; Satiety Response | 2013 |
Blunted glucagon but not epinephrine responses to hypoglycemia occurs in youth with less than 1 yr duration of type 1 diabetes mellitus.
Topics: Adolescent; Adult; Child; Diabetes Mellitus, Type 1; Disease Progression; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Young Adult | 2014 |
Characterization of residual β cell function in long-standing type 1 diabetes.
Topics: Adolescent; Adult; C-Peptide; Child; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Disease Progression; Down-Regulation; Female; Glucagon; Glucagon-Secreting Cells; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Postprandial Period; Young Adult | 2014 |
Evaluation of long-term treatment effect in a type 1 diabetes intervention trial: differences after stimulation with glucagon or a mixed meal.
Topics: Adolescent; Adult; Area Under Curve; Blood Glucose; C-Peptide; Chaperonin 60; Diabetes Mellitus, Type 1; Double-Blind Method; Fasting; Female; Food; Gastrointestinal Agents; Glucagon; Glucose; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Meals; Middle Aged; Peptide Fragments; Young Adult | 2014 |
Role of glucagon-like peptide-1 analogue versus amylin as an adjuvant therapy in type 1 diabetes in a closed loop setting with ePID algorithm.
Topics: Adolescent; Adult; Algorithms; Blood Glucose; Diabetes Mellitus, Type 1; Exenatide; Female; Glucagon; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Islet Amyloid Polypeptide; Male; Pancreas, Artificial; Peptides; Venoms; Young Adult | 2014 |
Glucose-dependent insulinotropic polypeptide augments glucagon responses to hypoglycemia in type 1 diabetes.
Topics: Adult; Blood Glucose; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 1; Double-Blind Method; Drug Synergism; Fatty Acids, Nonesterified; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glycerol; Hormones; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Treatment Outcome | 2015 |
Glucagon regulates orexin A secretion in humans and rodents.
Topics: Adipocytes; Adult; Animals; Diabetes Mellitus, Type 1; Double-Blind Method; Female; Glucagon; Glucose; Healthy Volunteers; Humans; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred BALB C; Neuropeptides; Orexins; Pancreas | 2014 |
Quantification of the glycemic response to microdoses of subcutaneous glucagon at varying insulin levels.
Topics: Adult; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Glucose Clamp Technique; Humans; Hypoglycemia; Insulin; Male; Middle Aged; Pancreas, Artificial | 2014 |
Postprandial glucose, insulin and incretin responses to different carbohydrate tolerance tests.
Topics: Adolescent; Adult; Aged; Biomarkers; Blood Glucose; C-Peptide; China; Cross-Over Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Female; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Humans; Incretins; Insulin; Male; Middle Aged; Postprandial Period; Predictive Value of Tests; Time Factors; Young Adult | 2015 |
Comparison of dual-hormone artificial pancreas, single-hormone artificial pancreas, and conventional insulin pump therapy for glycaemic control in patients with type 1 diabetes: an open-label randomised controlled crossover trial.
Topics: Adolescent; Adult; Aged; Blood Glucose; Child; Cross-Over Studies; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Infusion Pumps, Implantable; Insulin; Insulin Infusion Systems; Middle Aged; Pancreas, Artificial; Treatment Outcome; Young Adult | 2015 |
Effects of sitagliptin on counter-regulatory and incretin hormones during acute hypoglycaemia in patients with type 1 diabetes: a randomized double-blind placebo-controlled crossover study.
Topics: Adolescent; Adult; Cross-Over Studies; Diabetes Mellitus, Type 1; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Growth Hormone; Humans; Hypoglycemia; Incretins; Male; Middle Aged; Sitagliptin Phosphate; Young Adult | 2015 |
Comparison of appetite responses to high- and low-glycemic index postexercise meals under matched insulinemia and fiber in type 1 diabetes.
Topics: Adult; Appetite Regulation; Combined Modality Therapy; Cross-Over Studies; Diabetes Mellitus, Type 1; Diet, Diabetic; Dietary Fiber; Drug Therapy, Combination; Exercise; Glucagon; Glucagon-Like Peptide 1; Glycemic Index; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin Aspart; Insulin Glargine; Insulin, Long-Acting; Jogging; Male; Meals; Postprandial Period | 2015 |
Counter-regulatory hormone responses to hypoglycaemia in people with type 1 diabetes after 4 weeks of treatment with liraglutide adjunct to insulin: a randomized, placebo-controlled, double-blind, crossover trial.
Topics: Adult; Body Weight; Cross-Over Studies; Diabetes Mellitus, Type 1; Double-Blind Method; Drug Therapy, Combination; Female; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Clamp Technique; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Liraglutide; Male; Middle Aged | 2015 |
Fixed ratio dosing of pramlintide with regular insulin before a standard meal in patients with type 1 diabetes.
Topics: Adult; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Female; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Islet Amyloid Polypeptide; Male; Meals; Middle Aged; Postprandial Period; Single-Blind Method | 2015 |
Outpatient overnight glucose control with dual-hormone artificial pancreas, single-hormone artificial pancreas, or conventional insulin pump therapy in children and adolescents with type 1 diabetes: an open-label, randomised controlled trial.
Topics: Adolescent; Blood Glucose; Canada; Child; Cross-Over Studies; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Infusion Pumps, Implantable; Insulin; Insulin Infusion Systems; Male; Outpatients; Pancreas, Artificial; Treatment Outcome | 2015 |
Glucagon sensitivity and clearance in type 1 diabetes: insights from in vivo and in silico experiments.
Topics: Adult; Blood Glucose; Computer Simulation; Diabetes Mellitus, Type 1; Female; Glucagon; Gluconeogenesis; Glucose; Glucose Clamp Technique; Glycogenolysis; Hormones; Humans; Hypoglycemia; Liver; Male; Middle Aged; Pancreas, Artificial; Young Adult | 2015 |
Pharmacokinetics and pharmacodynamics of various glucagon dosages at different blood glucose levels.
Topics: Adult; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Female; Gastrointestinal Agents; Glucagon; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Male; Middle Aged | 2016 |
Single- and Dual-Hormone Artificial Pancreas for Overnight Glucose Control in Type 1 Diabetes.
Topics: Adolescent; Adult; Aged; Blood Glucose; Child; Cross-Over Studies; Diabetes Mellitus, Type 1; Dietary Carbohydrates; Dietary Fats; Drug Delivery Systems; Exercise; Female; Glucagon; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Pancreas, Artificial; Young Adult | 2016 |
[Clinical observation on the combined therapy of sitagliptin with insulin for patients with brittle diabetes].
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Drug Therapy, Combination; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Sitagliptin Phosphate | 2015 |
Saxagliptin co-therapy in C-peptide negative Type 1 diabetes does not improve counter-regulatory responses to hypoglycaemia.
Topics: Adamantane; Adult; Blood Glucose Self-Monitoring; Cross-Over Studies; Diabetes Mellitus, Type 1; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Drug Therapy, Combination; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Middle Aged; Monitoring, Ambulatory; Norepinephrine | 2016 |
Intranasal Glucagon for Treatment of Insulin-Induced Hypoglycemia in Adults With Type 1 Diabetes: A Randomized Crossover Noninferiority Study.
Topics: Administration, Intranasal; Adult; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Female; Glucagon; Hormones; Humans; Hypoglycemia; Insulin; Male; Middle Aged; Young Adult | 2016 |
Effects of subcutaneous, low-dose glucagon on insulin-induced mild hypoglycaemia in patients with insulin pump treated type 1 diabetes.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Female; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Injections, Subcutaneous; Insulin Antagonists; Insulin Aspart; Insulin Infusion Systems; Male; Middle Aged; Severity of Illness Index; Single-Blind Method; Young Adult | 2016 |
Day and night glycaemic control with a bionic pancreas versus conventional insulin pump therapy in preadolescent children with type 1 diabetes: a randomised crossover trial.
Topics: Blood Glucose; Child; Cross-Over Studies; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Male; Monitoring, Physiologic; Pancreas, Artificial; Time Factors; Treatment Outcome | 2016 |
Glucagon Nasal Powder: A Promising Alternative to Intramuscular Glucagon in Youth With Type 1 Diabetes.
Topics: Administration, Intranasal; Adolescent; Blood Glucose; Child; Child, Preschool; Cohort Studies; Cross-Over Studies; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Female; Glucagon; Humans; Hypoglycemia; Injections, Intramuscular; Insulin; Male; Nausea; Powders | 2016 |
Performance and safety of an integrated bihormonal artificial pancreas for fully automated glucose control at home.
Topics: Adolescent; Adult; Aged; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Female; Glucagon; Home Care Services; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin Infusion Systems; Insulins; Male; Middle Aged; Pancreas, Artificial; Pilot Projects; Treatment Outcome; Young Adult | 2016 |
Adjuvant Liraglutide and Insulin Versus Insulin Monotherapy in the Closed-Loop System in Type 1 Diabetes: A Randomized Open-Labeled Crossover Design Trial.
Topics: Adult; Area Under Curve; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hyperglycemia; Hypoglycemic Agents; Incidence; Insulin; Insulin Infusion Systems; Liraglutide; Male; Middle Aged; ROC Curve | 2016 |
Addition of Liraglutide to Insulin in Patients With Type 1 Diabetes: A Randomized Placebo-Controlled Clinical Trial of 12 Weeks.
Topics: Adult; Blood Glucose; Body Weight; Diabetes Mellitus, Type 1; Double-Blind Method; Drug Therapy, Combination; Female; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Liraglutide; Male; Middle Aged; Obesity; Overweight; Postprandial Period; Time Factors; Treatment Outcome | 2016 |
Comparative Pharmacokinetic/Pharmacodynamic Study of Liquid Stable Glucagon Versus Lyophilized Glucagon in Type 1 Diabetes Subjects.
Topics: Adult; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Double-Blind Method; Female; Gastrointestinal Agents; Glucagon; Humans; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Male; Middle Aged; Transdermal Patch; Young Adult | 2016 |
Randomized trial of a dual-hormone artificial pancreas with dosing adjustment during exercise compared with no adjustment and sensor-augmented pump therapy.
Topics: Adolescent; Adult; Biosensing Techniques; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Exercise; Female; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Male; Middle Aged; Pancreas, Artificial; Young Adult | 2016 |
Efficacy of single-hormone and dual-hormone artificial pancreas during continuous and interval exercise in adult patients with type 1 diabetes: randomised controlled crossover trial.
Topics: Adult; Algorithms; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Exercise; Female; Glucagon; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Pancreas, Artificial; Young Adult | 2016 |
Low-Carbohydrate Diet Impairs the Effect of Glucagon in the Treatment of Insulin-Induced Mild Hypoglycemia: A Randomized Crossover Study.
Topics: Adult; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Diet, Carbohydrate-Restricted; Fasting; Female; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Male; Middle Aged | 2017 |
Home use of a bihormonal bionic pancreas versus insulin pump therapy in adults with type 1 diabetes: a multicentre randomised crossover trial.
Topics: Adult; Bionics; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Female; Glucagon; Hormones; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Male; Middle Aged; Monitoring, Physiologic; Nausea; Pancreas, Artificial; Young Adult | 2017 |
Outpatient 60-hour day-and-night glucose control with dual-hormone artificial pancreas, single-hormone artificial pancreas, or sensor-augmented pump therapy in adults with type 1 diabetes: An open-label, randomised, crossover, controlled trial.
Topics: Activities of Daily Living; Adult; Blood Glucose; Combined Modality Therapy; Cross-Over Studies; Diabetes Mellitus, Type 1; Glucagon; Glycated Hemoglobin; Hormone Replacement Therapy; Humans; Hyperglycemia; Hypoglycemia; Infusion Pumps; Insulin; Insulin Infusion Systems; Middle Aged; Monitoring, Ambulatory; Pancreas, Artificial; Patient Education as Topic; Quebec; Risk | 2017 |
A multiscale, model-based analysis of the multi-tissue interplay underlying blood glucose regulation in type I diabetes.
Topics: Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus, Type 1; Glucagon; Glucose; Hepatocytes; Humans; Insulin; Liver; Metabolic Networks and Pathways; Models, Biological; Muscles | 2016 |
Liraglutide acutely suppresses glucagon, lipolysis and ketogenesis in type 1 diabetes.
Topics: Adult; Diabetes Mellitus, Type 1; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Fatty Acids, Nonesterified; Female; Ghrelin; Glucagon; Glucagon-Like Peptide-1 Receptor; Humans; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Insulin Infusion Systems; Ketone Bodies; Lipolysis; Liraglutide; Male; Middle Aged | 2017 |
Glucagon is absorbed from the rectum but does not hasten recovery from hypoglycaemia in patients with type 1 diabetes.
Topics: Administration, Rectal; Adult; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Insulin; Male; Time Factors; Treatment Outcome | 2008 |
Effect of vildagliptin on glucagon concentration during meals in patients with type 1 diabetes.
Topics: Adamantane; Adult; Diabetes Mellitus, Type 1; Feeding Behavior; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Hypoglycemia; Hypoglycemic Agents; Male; Nitriles; Pyrrolidines; Vildagliptin | 2008 |
Reducing postprandial hyperglycemia with adjuvant premeal pramlintide and postmeal insulin in children with type 1 diabetes mellitus.
Topics: Adolescent; Amyloid; Chemotherapy, Adjuvant; Child; Cross-Over Studies; Diabetes Mellitus, Type 1; Drug Administration Schedule; Feeding Behavior; Female; Glucagon; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Islet Amyloid Polypeptide; Male | 2009 |
Twenty-four-hour simultaneous subcutaneous Basal-bolus administration of insulin and amylin in adolescents with type 1 diabetes decreases postprandial hyperglycemia.
Topics: Adolescent; Amyloid; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Diet, Diabetic; Female; Glucagon; Hormones; Humans; Hyperglycemia; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Islet Amyloid Polypeptide; Male; Postprandial Period; Young Adult | 2009 |
Pramlintide lowered glucose excursions and was well-tolerated in adolescents with type 1 diabetes: results from a randomized, single-blind, placebo-controlled, crossover study.
Topics: Adolescent; Amyloid; Blood Glucose; Child; Cross-Over Studies; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glucagon; Humans; Hypoglycemic Agents; Insulin; Insulin Lispro; Islet Amyloid Polypeptide; Male; Single-Blind Method; Treatment Outcome | 2009 |
Association of T-cell reactivity with beta-cell function in recent onset type 1 diabetes patients.
Topics: Adolescent; Adult; Autoantigens; C-Peptide; Cells, Cultured; Child; Cytokines; Diabetes Mellitus, Type 1; Disease Progression; Female; Follow-Up Studies; Glucagon; Humans; Insulin-Secreting Cells; Male; T-Cell Antigen Receptor Specificity; Th1 Cells; Th2 Cells | 2010 |
Long-term metabolic and hormonal effects of exenatide on islet transplant recipients with allograft dysfunction.
Topics: Adult; Amyloid; Area Under Curve; C-Peptide; Demography; Diabetes Mellitus, Type 1; Exenatide; Female; Glucagon; Glucose; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Secretion; Islet Amyloid Polypeptide; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Middle Aged; Peptides; Primary Graft Dysfunction; Prospective Studies; Transplantation, Homologous; Venoms | 2009 |
Do the actions of glucagon-like peptide-1 on gastric emptying, appetite, and food intake involve release of amylin in humans?
Topics: Adult; Amyloid; Appetite; Body Mass Index; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 1; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Islet Amyloid Polypeptide; Reference Values; Single-Blind Method | 2010 |
Novel use of glucagon in a closed-loop system for prevention of hypoglycemia in type 1 diabetes.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Hormones; Humans; Hypoglycemia; Male; Treatment Outcome | 2010 |
A bihormonal closed-loop artificial pancreas for type 1 diabetes.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 1; Drug Delivery Systems; Female; Glucagon; Humans; Insulin; Insulin Lispro; Male; Middle Aged; Pancreas, Artificial; Young Adult | 2010 |
Efficacy determinants of subcutaneous microdose glucagon during closed-loop control.
Topics: Adult; Algorithms; Blood Glucose; Boston; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Infusions, Subcutaneous; Insulin; Insulin Infusion Systems; Insulin Lispro; Models, Biological; Monitoring, Physiologic; Pancreas, Artificial; Software | 2010 |
Antidiabetic actions of endogenous and exogenous GLP-1 in type 1 diabetic patients with and without residual β-cell function.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Male; Peptide Fragments; Triglycerides; Young Adult | 2011 |
Counter-regulatory hormone responses to spontaneous hypoglycaemia during treatment with insulin Aspart or human soluble insulin: a double-blinded randomized cross-over study.
Topics: Adolescent; Adult; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Double-Blind Method; Fatty Acids, Nonesterified; Female; Ghrelin; Glucagon; Hormones; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Aspart; Insulin, Isophane; Male; Middle Aged; Young Adult | 2011 |
Does the fat-protein meal increase postprandial glucose level in type 1 diabetes patients on insulin pump: the conclusion of a randomized study.
Topics: Adolescent; Blood Glucose; Blood Glucose Self-Monitoring; C-Peptide; Child; Diabetes Mellitus, Type 1; Dietary Fats; Dietary Proteins; Female; Glucagon; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Male; Postprandial Period | 2012 |
Effects of everyday life events on glucose, insulin, and glucagon dynamics in continuous subcutaneous insulin infusion-treated type 1 diabetes: collection of clinical data for glucose modeling.
Topics: Activities of Daily Living; Adult; Blood Glucose; Denmark; Diabetes Mellitus, Type 1; Dietary Carbohydrates; Exercise Test; Female; Glucagon; Glycated Hemoglobin; Heart Rate; Humans; Hypoglycemic Agents; Infusions, Subcutaneous; Insulin; Insulin Infusion Systems; Male; Middle Aged; Models, Theoretical | 2012 |
Vildagliptin reduces glucagon during hyperglycemia and sustains glucagon counterregulation during hypoglycemia in type 1 diabetes.
Topics: Adamantane; Adult; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glucagon; Glucagon-Secreting Cells; Glucose Clamp Technique; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Nitriles; Pyrrolidines; Vildagliptin; Young Adult | 2012 |
Feasibility of a bihormonal closed-loop system to control postexercise and postprandial glucose excursions.
Topics: Administration, Metronomic; Adult; Aged; Blood Glucose; Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 1; Exercise; Feasibility Studies; Female; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Infusions, Subcutaneous; Insulin; Insulin Infusion Systems; Male; Middle Aged; Pilot Projects; Postprandial Period | 2012 |
Glucagon increases circulating fibroblast growth factor 21 independently of endogenous insulin levels: a novel mechanism of glucagon-stimulated lipolysis?
Topics: 3T3-L1 Cells; Adult; Animals; Blotting, Western; Cell Differentiation; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Female; Fibroblast Growth Factors; Glucagon; Humans; Insulin; Lipolysis; Male; Mice; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction | 2013 |
Glucose-responsive insulin and glucagon delivery (dual-hormone artificial pancreas) in adults with type 1 diabetes: a randomized crossover controlled trial.
Topics: Adult; Algorithms; Biomarkers; Blood Glucose; Cross-Over Studies; Decision Support Techniques; Diabetes Mellitus, Type 1; Drug Administration Schedule; Drug Therapy, Combination; Female; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Infusion Pumps, Implantable; Insulin Aspart; Insulin Infusion Systems; Male; Pancreas, Artificial; Regression Analysis; Treatment Outcome | 2013 |
Impact of pramlintide on glucose fluctuations and postprandial glucose, glucagon, and triglyceride excursions among patients with type 1 diabetes intensively treated with insulin pumps.
Topics: Adult; Amyloid; Blood Glucose; Diabetes Mellitus, Type 1; Female; Fructosamine; Glucagon; Humans; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Islet Amyloid Polypeptide; Male; Middle Aged; Postprandial Period; Triglycerides | 2003 |
Effect of glucagon-like peptide 1 (7-36 amide) on insulin-mediated glucose uptake in patients with type 1 diabetes.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Humans; Hyperinsulinism; Insulin; Liver; Male; Neurotransmitter Agents; Peptide Fragments; Peptides | 2003 |
Effects of dipeptide administration on hypoglycaemic counterregulation in type 1 diabetes.
Topics: Adult; Age of Onset; Amino Acids; Blood Glucose; Cognition; Diabetes Mellitus, Type 1; Dipeptides; Female; Glucagon; Glucose Clamp Technique; Homeostasis; Humans; Hypoglycemia; Infusions, Intravenous; Insulin; Insulin Secretion; Male; Perception; Reference Values | 2003 |
The pathophysiology of diabetes involves a defective amplification of the late-phase insulin response to glucose by glucose-dependent insulinotropic polypeptide-regardless of etiology and phenotype.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Chronic Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Hyperglycemia; Insulin; Islets of Langerhans; Male; Middle Aged; Neurotransmitter Agents; Nuclear Proteins; Pancreatitis; Peptide Fragments; Phenotype; Protein Precursors; Transcription Factors | 2003 |
The insulin secretagogues glibenclamide and repaglinide do not influence growth hormone secretion in humans but stimulate glucagon secretion during profound insulin deficiency.
Topics: Blood Glucose; C-Peptide; Carbamates; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glucagon; Glucose Clamp Technique; Glyburide; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Hypoglycemic Agents; Insulin; Piperidines; Placebos; Potassium Channel Blockers; Somatostatin | 2004 |
Insulin-like growth factor I has a direct effect on glucose and protein metabolism, but no effect on lipid metabolism in type 1 diabetes.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glucagon; Glucose; Glucose Clamp Technique; Glycerol; Homeostasis; Human Growth Hormone; Humans; Insulin; Insulin-Like Growth Factor I; Kinetics; Leucine; Lipids; Lipolysis; Liver; Metabolic Clearance Rate; Oxidation-Reduction; Placebos; Proteins; Recombinant Proteins | 2004 |
Effect of sex on counterregulatory responses to exercise after antecedent hypoglycemia in type 1 diabetes.
Topics: Adaptation, Physiological; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Female; Glucagon; Glucose Clamp Technique; Growth Hormone; Homeostasis; Humans; Hydrocortisone; Hypoglycemia; Insulin; Male; Neurosecretory Systems; Norepinephrine; Oxygen Consumption; Pancreatic Polypeptide; Sex Factors | 2004 |
Exendin-4 normalized postcibal glycemic excursions in type 1 diabetes.
Topics: Adult; Aged; Analysis of Variance; Area Under Curve; Blood Glucose; Diabetes Mellitus, Type 1; Drug Administration Schedule; Exenatide; Female; Gastric Emptying; Glucagon; Humans; Injections, Subcutaneous; Insulin; Insulin Secretion; Male; Middle Aged; Peptides; Postprandial Period; Time Factors; Venoms | 2004 |
Differing physiological effects of epinephrine in type 1 diabetes and nondiabetic humans.
Topics: Adult; Autonomic Nervous System; Biopsy; Blood Glucose; Blood Pressure; Calorimetry, Indirect; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Heart Rate; Human Growth Hormone; Humans; Hydrocortisone; Insulin; Male; Muscle, Skeletal; Norepinephrine; Pancreatic Polypeptide; Sympathomimetics | 2005 |
The role of amylin and glucagon in the dampening of glycemic excursions in children with type 1 diabetes.
Topics: Adolescent; Amyloid; Blood Glucose; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Female; Glucagon; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin; Islet Amyloid Polypeptide; Male | 2005 |
The effect of pramlintide on hormonal, metabolic or symptomatic responses to insulin-induced hypoglycaemia in patients with type 1 diabetes.
Topics: Adult; Amyloid; Blood Glucose; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epinephrine; Female; Glucagon; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Hypoglycemic Agents; Insulin; Islet Amyloid Polypeptide; Male; Middle Aged; Norepinephrine | 2005 |
Xenotransplantation of porcine neonatal islets of Langerhans and Sertoli cells: a 4-year study.
Topics: Adolescent; Animals; Animals, Newborn; Blood Glucose; C-Peptide; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Glycated Hemoglobin; Graft Rejection; Graft Survival; Humans; Immunohistochemistry; Insulin; Islets of Langerhans Transplantation; Male; Sertoli Cells; Specific Pathogen-Free Organisms; Swine; Transplantation, Heterologous | 2005 |
Islet cell hormonal responses to hypoglycemia after human islet transplantation for type 1 diabetes.
Topics: Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemia; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Middle Aged | 2005 |
Effect of prior hyperglycemia on IL-6 responses to exercise in children with type 1 diabetes.
Topics: Adolescent; Blood Glucose; Child; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exercise Test; Female; Glucagon; Glucose Clamp Technique; Growth Substances; Humans; Hydrocortisone; Hyperglycemia; Insulin; Interleukin-6; Male; Oxygen Consumption | 2006 |
The 10-s maximal sprint: a novel approach to counter an exercise-mediated fall in glycemia in individuals with type 1 diabetes.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exercise Test; Fatty Acids, Nonesterified; Glucagon; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Lactic Acid; Male; Norepinephrine; Running | 2006 |
Glycemic thresholds for activation of counterregulatory hormone and symptom responses in islet transplant recipients.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Human Growth Hormone; Humans; Hypoglycemia; Insulin; Islets of Langerhans Transplantation; Male; Middle Aged; Transplantation | 2007 |
Evaluation of beta-cell function in diabetic Taiwanese children using a 6-min glucagon test.
Topics: Adolescent; C-Peptide; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Evaluation Studies as Topic; Female; Glucagon; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Infant; Islets of Langerhans; Male; ROC Curve; Taiwan | 2008 |
The role of prandial pramlintide in the treatment of adolescents with type 1 diabetes.
Topics: Adolescent; Amyloid; Blood Glucose; Diabetes Mellitus, Type 1; Drug Administration Schedule; Drug Therapy, Combination; Female; Gastric Emptying; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Infusions, Parenteral; Injections, Subcutaneous; Insulin; Islet Amyloid Polypeptide; Male; Risk Assessment; Time Factors; Treatment Outcome | 2007 |
Effects of dietary fiber on postprandial glycemic profiles in diabetic patients submitted to continuous programmed insulin infusion.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Dietary Fiber; Glucagon; Humans; Insulin; Insulin Infusion Systems; Male; Middle Aged; Random Allocation | 1984 |
Prandial insulin requirements in insulin-dependent diabetics: effects of size, time of day, and sequence of meals.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diet; Dose-Response Relationship, Drug; Energy Intake; Female; Glucagon; Humans; Insulin; Male; Time Factors | 1983 |
Semisynthetic human insulin and purified pork insulin do not differ in their biological potency.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Growth Hormone; Humans; Hydrocortisone; Insulin; Insulin, Regular, Pork; Male; Norepinephrine; Prolactin | 1984 |
Regulation of insulin-like growth factor binding protein-1 (IGFBP-1) in insulin-dependent diabetes mellitus. Effects of hyperglycaemia and insulin.
Topics: Adult; Blood Glucose; Carrier Proteins; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; Humans; Hyperglycemia; Insulin; Insulin Antagonists; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor I; Male | 1994 |
Muscarinic cholinergic antagonism does not enhance recovery from hypoglycemia in IDDM.
Topics: Adult; Atropine; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose; Growth Hormone; Heart Rate; Homeostasis; Hormones; Humans; Hydrocortisone; Hypoglycemia; Infusions, Intravenous; Insulin; Male; Muscarinic Antagonists; Pancreatic Polypeptide | 1995 |
Protein content of the evening meal and nocturnal plasma glucose regulation in type-I diabetic subjects.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Dietary Fats; Dietary Proteins; Fatty Acids, Nonesterified; Glucagon; Growth Hormone; Humans; Hydrocortisone; Middle Aged | 1995 |
Circadian variation of insulin requirement in insulin dependent diabetes mellitus the relationship between circadian change in insulin demand and diurnal patterns of growth hormone, cortisol and glucagon during euglycemia.
Topics: Adolescent; Adult; Algorithms; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Insulin; Liver; Male | 1995 |
Blood glucose estimation and symptoms during hyperglycemia and hypoglycemia in patients with insulin-dependent diabetes mellitus.
Topics: Adult; Affect; Blood Glucose; Cluster Analysis; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Growth Hormone; Hormones; Humans; Hydrocortisone; Hyperglycemia; Hypoglycemia; Male; Norepinephrine; Surveys and Questionnaires | 1995 |
Impaired net hepatic glycogen synthesis in insulin-dependent diabetic subjects during mixed meal ingestion. A 13C nuclear magnetic resonance spectroscopy study.
Topics: Adult; Blood Glucose; Carbon Isotopes; Diabetes Mellitus, Type 1; Eating; Energy Intake; Female; Glucagon; Humans; Liver; Liver Glycogen; Magnetic Resonance Spectroscopy; Male; Reference Values; Time Factors | 1995 |
Long-term recovery from unawareness, deficient counterregulation and lack of cognitive dysfunction during hypoglycaemia, following institution of rational, intensive insulin therapy in IDDM.
Topics: Adult; Awareness; Blood Glucose; Body Mass Index; Cognition; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Glycated Hemoglobin; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Male; Norepinephrine; Pancreatic Polypeptide; Reference Values; Time Factors | 1994 |
Prevalence and predictive value of islet cell antibodies and insulin autoantibodies in women with gestational diabetes.
Topics: Autoantibodies; Blood Glucose; Cohort Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Follow-Up Studies; Glucagon; Glucose Tolerance Test; Histocompatibility Testing; Humans; Insulin Antibodies; Islets of Langerhans; Predictive Value of Tests; Pregnancy; Prevalence; Reference Values; Retrospective Studies; Risk Factors; Sensitivity and Specificity; Time Factors | 1994 |
Combination of nicotinamide and steroid versus nicotinamide in recent-onset IDDM. The IMDIAB II Study.
Topics: Adolescent; Adult; Age Factors; Anti-Inflammatory Agents; C-Peptide; Child; Child, Preschool; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Female; Follow-Up Studies; Glucagon; Glycated Hemoglobin; Humans; Insulin; Male; Niacinamide; Pregnenediones | 1994 |
Theophylline enhances glucose recovery after hypoglycemia in healthy man and in type I diabetic patients.
Topics: Adult; Blood Glucose; Cyclic AMP; Diabetes Mellitus, Type 1; Double-Blind Method; Drug Synergism; Glucagon; Humans; Hydrocortisone; Hypoglycemia; Insulin; Liver; Male; Single-Blind Method; Theophylline; Time Factors | 1994 |
Intranasal glucagon treatment relieves hypoglycaemia in children with type 1 (insulin-dependent) diabetes mellitus.
Topics: Administration, Intranasal; Blood Glucose; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemia; Injections, Subcutaneous; Insulin; Male; Nasal Mucosa; Nausea | 1993 |
Glycemic actions of alanine and terbutaline in IDDM.
Topics: Administration, Oral; Alanine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Humans; Injections, Subcutaneous; Insulin; Kinetics; Lactates; Random Allocation; Reference Values; Terbutaline | 1993 |
Alanine and terbutaline in treatment of hypoglycemia in IDDM.
Topics: 3-Hydroxybutyric Acid; Administration, Oral; Alanine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Humans; Hydroxybutyrates; Hypoglycemia; Injections, Subcutaneous; Insulin; Lactates; Pancreatic Polypeptide; Terbutaline; Time Factors | 1993 |
Influence of combined C-peptide and insulin administration on renal function and metabolic control in diabetes type 1.
Topics: Adolescent; Adult; Albuminuria; Blood Glucose; Blood-Retinal Barrier; C-Peptide; Diabetes Mellitus, Type 1; Double-Blind Method; Female; Fluorescein; Fluoresceins; Fructosamine; Glomerular Filtration Rate; Glucagon; Glycated Hemoglobin; Growth Hormone; Hexosamines; Humans; Insulin; Insulin Infusion Systems; Kidney; Male; Norepinephrine; Pilot Projects | 1993 |
Clinical evaluation of biosynthetic glucagon treatment for recovery from hypoglycemia developed in diabetic patients. The GL-G Hypoglycemia Study Group.
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Injections, Intramuscular; Injections, Intravenous; Insulin; Male; Middle Aged; Recombinant Proteins | 1993 |
The hemodynamic abnormalities in short-term insulin deficiency: the role of prostaglandin inhibition.
Topics: 3-Hydroxybutyric Acid; 6-Ketoprostaglandin F1 alpha; Acetoacetates; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Double-Blind Method; Echocardiography; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Heart Rate; Hemodynamics; Humans; Hydroxybutyrates; Indomethacin; Insulin; Male; Muscle, Skeletal; Norepinephrine; Reference Values; Regional Blood Flow; Stroke Volume; Systole; Ventricular Function, Left; Ventricular Function, Right | 1996 |
Comparison of the ability of bread versus bread plus meat to treat and prevent subsequent hypoglycemia in patients with insulin-dependent diabetes mellitus.
Topics: Adult; Blood Glucose; Bread; Diabetes Mellitus, Type 1; Energy Intake; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Male; Meat; Time Factors | 1996 |
Cyclosporin A does not delay insulin dependency in asymptomatic IDDM patients.
Topics: Adolescent; Adult; Arginine; Blood Glucose; C-Peptide; Cyclosporine; Diabetes Mellitus, Type 1; Female; Follow-Up Studies; Glucagon; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Immunosuppressive Agents; Insulin; Insulin Secretion; Islets of Langerhans; Male; Reference Values | 1995 |
Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients.
Topics: Adult; Analysis of Variance; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Male; Peptide Fragments; Protein Precursors; Time Factors | 1996 |
Symptoms, hormones, and glucose fluxes during a gradual hypoglycaemia induced by intraperitoneal vs venous insulin infusion in Type I diabetes.
Topics: Adult; Analysis of Variance; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Growth Hormone; Hormones; Humans; Hydrocortisone; Hypoglycemia; Infusions, Intravenous; Infusions, Parenteral; Insulin; Insulin Infusion Systems; Kinetics; Male; Radioisotope Dilution Technique; Time Factors; Tritium | 1995 |
Diazoxide treatment at onset preserves residual insulin secretion in adults with autoimmune diabetes.
Topics: Adult; Autoantibodies; C-Peptide; Diabetes Mellitus, Type 1; Diazoxide; Drug Therapy, Combination; Female; Follow-Up Studies; Glucagon; Glutamate Decarboxylase; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Placebos; Time Factors | 1996 |
More uniform diurnal blood glucose control and a reduction in daily insulin dosage on addition of glibenclamide to insulin in type 1 diabetes mellitus: role of enhanced insulin sensitivity.
Topics: Adult; Aged; Blood Glucose; Body Weight; C-Peptide; Cholesterol; Circadian Rhythm; Cross-Over Studies; Diabetes Mellitus, Type 1; Double-Blind Method; Drug Therapy, Combination; Glucagon; Glyburide; Glycated Hemoglobin; Glycosuria; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Middle Aged; Placebos; Triglycerides | 1995 |
Effect of octreotide on blood glucose and counterregulatory hormones in insulin-dependent diabetic patients: the role of dose and route of administration.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Drug Administration Routes; Drug Administration Schedule; Epinephrine; Female; Glucagon; Growth Hormone; Hormones; Humans; Hydrocortisone; Injections, Subcutaneous; Insulin; Male; Middle Aged; Octreotide | 1996 |
Ketosis resistance in fibrocalculous pancreatic diabetes: II. Hepatic ketogenesis after oral medium-chain triglycerides.
Topics: Adipose Tissue; Administration, Oral; Adult; Blood Glucose; C-Peptide; Carnitine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Fatty Acids; Fatty Acids, Nonesterified; Female; Glucagon; Glycerol; Humans; Hydroxybutyrates; Ketones; Liver; Male; Triglycerides | 1997 |
Subcutaneous glucagon-like peptide I combined with insulin normalizes postcibal glycemic excursions in IDDM.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Male; Middle Aged; Pancreatic Polypeptide; Peptide Fragments; Time Factors | 1997 |
Counterregulatory hormone and symptom responses to hypoglycaemia in diabetic children.
Topics: Adolescent; Blood Glucose; Body Mass Index; C-Peptide; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose; Glucose Clamp Technique; Glycated Hemoglobin; Growth Hormone; Hormones; Humans; Hydrocortisone; Hypoglycemia; Insulin; Male; Norepinephrine; Time Factors | 1997 |
Effects of C-peptide on insulin-induced hypoglycaemia and its counterregulatory responses in IDDM patients.
Topics: Adult; Area Under Curve; Blood Glucose; C-Peptide; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Male; Pilot Projects; Radioimmunoassay | 1997 |
High-dose intravenous insulin infusion versus intensive insulin treatment in newly diagnosed IDDM.
Topics: Adolescent; Adult; C-Peptide; Diabetes Mellitus, Type 1; Fasting; Female; Food; Glucagon; Glycated Hemoglobin; Humans; Infusions, Intravenous; Insulin; Islets of Langerhans; Male | 1997 |
Effects of cholinergic blockade on nocturnal thyrotropin and growth hormone (GH) secretion in type I diabetes mellitus: further evidence supporting somatostatin's involvement in GH suppression.
Topics: Administration, Oral; Adult; Blood Glucose; Circadian Rhythm; Cohort Studies; Diabetes Mellitus, Type 1; Double-Blind Method; Female; Glucagon; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Hydrocortisone; Insulin-Like Growth Factor I; Male; Muscarinic Antagonists; Pirenzepine; Somatostatin; Thyrotropin | 1997 |
Recombinant human insulin-like growth factor-I abolishes changes in insulin requirements consequent upon growth hormone pulsatility in young adults with type I diabetes mellitus.
Topics: Adolescent; Adult; Blood Glucose; Child; Diabetes Mellitus, Type 1; Double-Blind Method; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Clamp Technique; Human Growth Hormone; Humans; Insulin; Insulin-Like Growth Factor I; Ketones; Male; Octreotide; Recombinant Proteins | 1998 |
Early postnatal hypoglycaemia in newborn infants of diabetic mothers.
Topics: Adult; Analysis of Variance; Blood Glucose; Cohort Studies; Diabetes Mellitus, Type 1; Diabetes, Gestational; Female; Fetal Blood; Glucagon; Glycated Hemoglobin; Humans; Hypoglycemia; Incidence; Infant, Newborn; Infant, Newborn, Diseases; Insulin-Like Growth Factor I; Male; Postnatal Care; Pregnancy; Pregnancy in Diabetics; Sweden | 1997 |
Effect of octreotide on growth hormone, IGF-I, IGFBP-3, glucagon, cortisol and epinephrine response to insulin-induced hypoglycaemia in insulin-dependent diabetic patients.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Hormones; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Male; Octreotide | 1997 |
Counterregulatory hormone responses after long-term continuous subcutaneous insulin infusion with lispro insulin.
Topics: Adult; Blood Glucose; Body Mass Index; Cross-Over Studies; Diabetes Mellitus, Type 1; Double-Blind Method; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Glycated Hemoglobin; Homeostasis; Hormones; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Insulin Lispro; Male; Middle Aged | 1998 |
Induction of beta-cell rest in type 1 diabetes. Studies on the effects of octreotide and diazoxide.
Topics: Adult; Antihypertensive Agents; Blood Glucose; C-Peptide; Data Interpretation, Statistical; Diabetes Mellitus, Type 1; Diazoxide; Female; Food; Glucagon; Glycated Hemoglobin; Hormones; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Octreotide; Postprandial Period | 1998 |
Counterregulatory hormones in insulin-treated diabetic patients admitted to an accident and emergency department with hypoglycaemia.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 1; Emergency Medical Services; Epinephrine; Female; Glucagon; Glucose; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Male; Middle Aged; Regression Analysis | 1998 |
Implantation of standardized beta-cell grafts in a liver segment of IDDM patients: graft and recipients characteristics in two cases of insulin-independence under maintenance immunosuppression for prior kidney graft.
Topics: Adolescent; Adult; Autoantibodies; Blood Glucose; C-Peptide; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Glucagon; Glutamate Decarboxylase; Glycated Hemoglobin; Histocompatibility Testing; Humans; Islets of Langerhans Transplantation; Kidney Transplantation; Liver; Male; Middle Aged; Tissue Donors; Transplantation, Heterotopic | 1998 |
Effect of continuous subcutaneous insulin infusion with lispro on hepatic responsiveness to glucagon in type 1 diabetes.
Topics: Adult; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Double-Blind Method; Female; Glucagon; Gluconeogenesis; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Insulin Infusion Systems; Insulin Lispro; Liver; Male; Somatostatin | 1998 |
Effect of bacille Calmette-Guérin vaccination on C-peptide secretion in children newly diagnosed with IDDM.
Topics: Adolescent; BCG Vaccine; C-Peptide; Child; Diabetes Mellitus, Type 1; Double-Blind Method; Fasting; Female; Follow-Up Studies; Glucagon; Glycated Hemoglobin; Humans; Insulin; Insulin Secretion; Male; Time Factors | 1998 |
Impact of nocturnal hypoglycemia on hypoglycemic cognitive dysfunction in type 1 diabetes.
Topics: Adult; Analysis of Variance; Blood Glucose; Circadian Rhythm; Cognition; Cognition Disorders; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose; Glucose Clamp Technique; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Neuropsychological Tests; Norepinephrine; Pancreatic Polypeptide | 1998 |
Effects of low-dose recombinant human insulin-like growth factor-I on insulin sensitivity, growth hormone and glucagon levels in young adults with insulin-dependent diabetes mellitus.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Double-Blind Method; Glucagon; Glucose Clamp Technique; Growth Hormone; Humans; Hyperinsulinism; Insulin; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Recombinant Proteins | 1998 |
The amylin analog pramlintide improves glycemic control and reduces postprandial glucagon concentrations in patients with type 1 diabetes mellitus.
Topics: Adult; Amyloid; Blood Glucose; Circadian Rhythm; Cross-Over Studies; Diabetes Mellitus, Type 1; Double-Blind Method; Eating; Glucagon; Human Growth Hormone; Humans; Hypoglycemic Agents; Insulin; Islet Amyloid Polypeptide; Leptin; Male; Middle Aged; Osmolar Concentration; Proteins; Time Factors | 1999 |
Lipophilic thiamine treatment in long-standing insulin-dependent diabetes mellitus.
Topics: Adolescent; Age of Onset; C-Peptide; Child; Child, Preschool; Diabetes Mellitus, Type 1; Double-Blind Method; Glucagon; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Placebos; Reference Values; Thiamine; Thiamine Monophosphate; Time Factors | 1999 |
Effects of the amylin analogue pramlintide on hepatic glucagon responses and intermediary metabolism in Type 1 diabetic subjects.
Topics: Adult; Amyloid; Blood Glucose; Catecholamines; Cross-Over Studies; Diabetes Mellitus, Type 1; Double-Blind Method; Fasting; Glucagon; Human Growth Hormone; Humans; Hypoglycemic Agents; Insulin; Islet Amyloid Polypeptide; Liver; Male; Middle Aged; Placebos | 1999 |
Circulating insulin inhibits glucagon secretion induced by arginine in type 1 diabetes.
Topics: Adult; Arginine; Blood Glucose; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Female; Glucagon; Humans; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Male; Middle Aged; Pancreas | 2000 |
Insulin and glucagon secretion in patients with slowly progressing autoimmune diabetes (LADA).
Topics: Adult; Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose; Humans; Insulin; Male | 2000 |
Continuous intraperitoneal insulin infusion partly restores the glucagon response to hypoglycaemia in type 1 diabetic patients.
Topics: Adult; Area Under Curve; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Infusion Pumps, Implantable; Infusions, Parenteral; Injections, Intravenous; Injections, Subcutaneous; Insulin; Male; Middle Aged; Treatment Outcome | 2000 |
Influence of acarbose on post-prandial insulin requirements in patients with Type 1 diabetes.
Topics: Acarbose; Adult; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Double-Blind Method; Female; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Insulin; Male; Peptide Fragments; Postprandial Period; Protein Precursors; Triglycerides | 2000 |
Gender-related differences in counterregulatory responses to antecedent hypoglycemia in normal humans.
Topics: Activity Cycles; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Hormones; Human Growth Hormone; Humans; Hydrocortisone; Hyperinsulinism; Hypoglycemia; Infusions, Intravenous; Insulin; Male; Muscle, Skeletal; Norepinephrine; Pancreatic Polypeptide; Peroneal Nerve; Reference Values; Sex Characteristics; Sympathetic Nervous System | 2000 |
Effect of nutrient ingestion on glucagon-like peptide 1 (7-36 amide) secretion in human type 1 and type 2 diabetes.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Eating; Female; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Male; Middle Aged; Peptide Fragments; Radioimmunoassay | 2000 |
Combination of continuous subcutaneous infusion of insulin and octreotide in Type 1 diabetic patients.
Topics: Adult; Alanine; Blood Glucose; Calorimetry, Indirect; Circadian Rhythm; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Fatty Acids, Nonesterified; Glucagon; Glycated Hemoglobin; Hormones; Human Growth Hormone; Humans; Infusions, Parenteral; Insulin; Insulin Infusion Systems; Lactates; Male; Octreotide | 2001 |
Physiological responses during hypoglycaemia induced by regular human insulin or a novel human analogue, insulin glargine.
Topics: Adult; Blood Glucose; Blood Pressure; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 1; Double-Blind Method; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Heart Rate; Human Growth Hormone; Humans; Hydrocortisone; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Glargine; Insulin, Long-Acting; Male; Norepinephrine; Recombinant Proteins; Reference Values | 2000 |
Differential effects of fasting and dehydration in the pathogenesis of diabetic ketoacidosis.
Topics: Adult; Analysis of Variance; Bicarbonates; Blood Glucose; Body Weight; Dehydration; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Epinephrine; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Insulin; Ketone Bodies; Male | 2001 |
Mini-dose glucagon rescue for hypoglycemia in children with type 1 diabetes.
Topics: Adolescent; Blood Glucose; Blood Glucose Self-Monitoring; Child; Child, Preschool; Diabetes Mellitus, Type 1; Gastroenteritis; Gastrointestinal Agents; Glucagon; Humans; Hypoglycemia; Injections, Subcutaneous; Insulin; Parents | 2001 |
Epipen as an alternative to glucagon in the treatment of hypoglycemia in children with diabetes.
Topics: Adrenergic beta-Agonists; Blood Glucose; Child; Cross-Over Studies; Diabetes Mellitus, Type 1; Epinephrine; Gastrointestinal Agents; Glucagon; Glycated Hemoglobin; Humans; Hypoglycemia; Insulin; Kinetics | 2001 |
Effects of amino acids and glucagon on renal hemodynamics in type 1 diabetes.
Topics: Adult; Amino Acids; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Female; Glomerular Filtration Rate; Glucagon; Humans; Indomethacin; Kidney Glomerulus; Male; Octreotide; Prostaglandins; Renal Circulation; Vasoconstrictor Agents | 2002 |
Impaired beta-cell function, incretin effect, and glucagon suppression in patients with type 1 diabetes who have normal fasting glucose.
Topics: Arginine; Autoantibodies; Blood Glucose; Diabetes Mellitus, Type 1; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Peptide Fragments; Reference Values | 2002 |
The human amylin analog, pramlintide, corrects postprandial hyperglucagonemia in patients with type 1 diabetes.
Topics: Adolescent; Adult; Amyloid; Blood Glucose; Diabetes Mellitus, Type 1; Double-Blind Method; Fasting; Female; Food; Glucagon; Humans; Hypoglycemic Agents; Islet Amyloid Polypeptide; Kinetics; Male; Middle Aged; Placebos | 2002 |
Glucagon suppression with low-dose intramuscular insulin therapy in diabetic ketoacidosis.
Topics: Blood Glucose; Child; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Glucagon; Humans; Injections, Intramuscular; Insulin; Potassium; Prospective Studies; Sodium | 1979 |
Hyperglucagonemia and its suppression. Importance in the metabolic control of diabetes.
Topics: Adult; Blood Glucose; Depression, Chemical; Diabetes Mellitus, Type 1; Diet, Diabetic; Glucagon; Glycosuria; Humans; Insulin; Somatostatin | 1978 |
Comparison of the suppressive effects of elevated plasma glucose and free fatty acid levels on glucagon secretion in normal and insulin-dependent diabetic subjects. Evidence for selective alpha-cell insensitivity to glucose in diabetes mellitus.
Topics: Adult; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Humans; Hyperglycemia; Insulin; Islets of Langerhans; Male; Receptors, Drug | 1976 |
Blood glucose response to stress hormone exposure in healthy man and insulin dependent diabetic patients: prediction by computer modeling.
Topics: Adult; Blood Glucose; Computer Simulation; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Growth Hormone; Humans; Hydrocortisone; Insulin; Male; Somatostatin | 1992 |
Protein intake and blood glucose as modulators of GFR in hyperfiltering diabetic patients.
Topics: Adult; Blood Glucose; Creatinine; Diabetes Mellitus, Type 1; Dietary Proteins; Glomerular Filtration Rate; Glucagon; Humans; Male; Middle Aged; Renal Circulation; Urea | 1992 |
Intranasal glucagon in the treatment of hypoglycaemic attacks in children: experience at a summer camp.
Topics: Administration, Intranasal; Adolescent; Blood Glucose; Camping; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemia; Injections, Subcutaneous; Insulin; Male | 1992 |
Symptomatic and hormonal hypoglycaemic responses to human and porcine insulin in patients with type I diabetes mellitus.
Topics: Adult; Analysis of Variance; Animals; Awareness; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Growth Hormone; Heart Rate; Humans; Hydrocortisone; Hypoglycemia; Insulin; Norepinephrine; Reaction Time; Recombinant Proteins; Reflex; Swine | 1992 |
Hormonal counterregulation, symptom awareness, and neurophysiological function in type 1 diabetes during insulin-induced hypoglycaemia.
Topics: Adult; Animals; Awareness; Blood Glucose; Brain Stem; Diabetes Mellitus, Type 1; Double-Blind Method; Epinephrine; Evoked Potentials, Auditory; Evoked Potentials, Somatosensory; Female; Glucagon; Growth Hormone; Homeostasis; Humans; Hydrocortisone; Hypoglycemia; Insulin; Insulin Infusion Systems; Male; Norepinephrine; Random Allocation; Recombinant Proteins; Swine; Time Factors | 1992 |
Natural course of remission in IDDM during 1st yr after diagnosis.
Topics: Adult; Autoantibodies; Blood Glucose; C-Peptide; Cyclosporine; Diabetes Mellitus, Type 1; Female; Follow-Up Studies; Glucagon; Glycated Hemoglobin; Humans; Insulin; Insulin Antibodies; Islets of Langerhans; Male; Probability; Remission, Spontaneous | 1992 |
Effect of captopril on renal functional reserve in type 1 (insulin-dependent) diabetes mellitus.
Topics: Adult; Blood Pressure; Captopril; Diabetes Mellitus, Type 1; Double-Blind Method; Female; Glucagon; Humans; Kidney; Kidney Function Tests; Male; Middle Aged | 1991 |
Metabolic and hormonal studies of type 1 (insulin-dependent) diabetic patients after successful pancreas and kidney transplantation.
Topics: Adult; Arginine; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose Tolerance Test; Growth Hormone; Hormones; Humans; Insulin; Kidney Transplantation; Male; Norepinephrine; Pancreas Transplantation; Prolactin; Prospective Studies; Reference Values | 1991 |
A comparative study on the hormonal responses to insulin-induced hypoglycaemia using semisynthetic human insulin and pork insulin in patients with type 1 diabetes mellitus.
Topics: Adult; Animals; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Hormones; Humans; Hydrocortisone; Hypoglycemia; Insulin; Insulin, Regular, Pork; Male; Norepinephrine; Pancreatic Polypeptide; Pulse; Recombinant Proteins; Somatostatin; Swine | 1990 |
Somatostatin analogue, octreotide, reduces increased glomerular filtration rate and kidney size in insulin-dependent diabetes.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Glomerular Filtration Rate; Glucagon; Growth Hormone; Humans; Hypertrophy; Insulin-Like Growth Factor I; Kidney; Male; Middle Aged; Octreotide; Single-Blind Method | 1991 |
Continuous subcutaneous octreotide infusion: dose-response relationships between metabolic effects and octreotide clearance in patients with insulin-dependent (type 1) diabetes.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Female; Glucagon; Growth Hormone; Humans; Insulin; Metabolic Clearance Rate; Octreotide; Pancreatic Polypeptide | 1991 |
A new non-invasive method for treating insulin-reaction: intranasal lyophylized glucagon.
Topics: Administration, Intranasal; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Freeze Drying; Glucagon; Humans; Hypoglycemia; Injections, Intravenous; Injections, Subcutaneous; Insulin | 1990 |
Plasma C-peptide levels and clinical remissions in recent-onset type I diabetic patients treated with cyclosporin A and insulin.
Topics: Adult; Biomarkers; Blood Glucose; C-Peptide; Clinical Trials as Topic; Cyclosporins; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Eating; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Male; Reference Values | 1990 |
[Effect of pancreatin on diabetes mellitus in chronic pancreatitis].
Topics: Blood Glucose; C-Peptide; Chronic Disease; Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Pancreatic Function Tests; Pancreatic Polypeptide; Pancreatin; Pancreatitis | 1990 |
Reduction of insulin resistance by combined kidney-pancreas transplantation in type 1 (insulin-dependent) diabetic patients.
Topics: Adult; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glycated Hemoglobin; Humans; Insulin; Insulin Infusion Systems; Insulin Resistance; Kidney Failure, Chronic; Kidney Transplantation; Male; Pancreas Transplantation; Reference Values | 1990 |
Comparison of intramuscular glucagon and intravenous dextrose in the treatment of hypoglycaemic coma in an accident and emergency department.
Topics: Diabetes Mellitus, Type 1; Diabetic Coma; Emergency Service, Hospital; Female; Glucagon; Glucose; Humans; Hyperglycemic Hyperosmolar Nonketotic Coma; Injections, Intramuscular; Injections, Intravenous; Male; Middle Aged | 1990 |
Efficacy of bedtime NPH insulin with daytime sulfonylurea for subpopulation of type II diabetic subjects.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Eating; Fasting; Glucagon; Glyburide; Humans; Insulin, Isophane; Middle Aged; Random Allocation | 1989 |
Effect of nicotinamide treatment on the residual insulin secretion in type 1 (insulin-dependent) diabetic patients.
Topics: Adult; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Glycated Hemoglobin; HLA-DR Antigens; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Niacinamide | 1989 |
Metabolic effects of long-acting somatostatin analogue (sandostatin) in type I diabetic patients on conventional therapy.
Topics: Adult; Blood Glucose; Circadian Rhythm; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Glucagon; Glycated Hemoglobin; Growth Hormone; Humans; Insulin; Lipids; Male; Octreotide; Random Allocation | 1989 |
Effects of a somatostatin derivative (SMS 201-995) on postprandial hyperglycemia in insulin-dependent diabetics studied by means of a closed-loop device.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Food; Glucagon; Humans; Insulin; Male; Middle Aged; Octreotide; Time Factors | 1989 |
Intranasal glucagon as remedy for hypoglycemia. Studies in healthy subjects and type I diabetic patients.
Topics: Administration, Intranasal; Adult; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Insulin; Kinetics; Middle Aged; Random Allocation; Reference Values | 1989 |
Efficacy, pharmacokinetics and tolerability of a somatostatin analogue (L-363,586) in insulin-dependent diabetes mellitus.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Food; Glucagon; Growth Hormone; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged; Peptides, Cyclic; Somatostatin; Triglycerides; Xylose | 1986 |
Plasma somatostatin and plasma glucagon in long-term IDDM without residual B-cell function. No effect of different long-term metabolic control.
Topics: Adult; Arginine; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Islets of Langerhans; Male; Somatostatin; Time Factors | 1986 |
Greater efficacy of pulsatile insulin in type I diabetics critically depends on plasma glucagon levels.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Infusions, Intravenous; Insulin; Kinetics; Male; Somatostatin | 1987 |
Insulin resistance following nocturnal hypoglycaemia in insulin-dependent diabetes mellitus.
Topics: Adult; Circadian Rhythm; Diabetes Mellitus, Type 1; Glucagon; Glucose Tolerance Test; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Insulin Resistance; Male; Somatostatin | 1987 |
The antidiabetic action of somatostatin-28 as assessed by the artificial endocrine pancreas: greater potency than somatostatin-14.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; Homeostasis; Humans; Insulin; Insulin Infusion Systems; Male; Middle Aged; Somatostatin; Somatostatin-28 | 1987 |
Effect of intranasal glucagon on blood glucose levels in healthy subjects and hypoglycaemic patients with insulin-dependent diabetes.
Topics: Administration, Intranasal; Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Evaluation Studies as Topic; Female; Glucagon; Humans; Hypoglycemia; Insulin; Male; Radioimmunoassay | 1988 |
Cyclosporin-induced remission of IDDM after early intervention. Association of 1 yr of cyclosporin treatment with enhanced insulin secretion. The Canadian-European Randomized Control Trial Group.
Topics: Adolescent; Adult; Blood Glucose; Blood Pressure; C-Peptide; Child; Clinical Trials as Topic; Cyclosporins; Diabetes Mellitus, Type 1; Double-Blind Method; Female; Glucagon; Glycated Hemoglobin; Humans; Insulin; Insulin Secretion; Male; Random Allocation; Regression Analysis | 1988 |
Metabolic effects of continuous subcutaneous insulin infusion: evidence that a rise and fall of portal vein insulin concentration with each major meal facilitates post-absorptive glycemic control.
Topics: Adult; Body Composition; C-Peptide; Cholesterol; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Eating; Glucagon; Glycated Hemoglobin; Humans; Insulin; Insulin Infusion Systems; Middle Aged; Random Allocation; Triglycerides | 1988 |
Pulsatile insulin delivery is more efficient than continuous infusion in modulating islet cell function in normal subjects and patients with type 1 diabetes.
Topics: Adult; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Insulin; Insulin Infusion Systems; Islets of Langerhans; Male; Pulsatile Flow; Reference Values | 1988 |
Glucagon responses to intravenous arginine and oral glucose in insulin-dependent diabetic patients during six months conventional or continuous subcutaneous insulin infusion.
Topics: Administration, Oral; Adult; Arginine; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Growth Hormone; Humans; Injections, Intravenous; Insulin; Insulin Infusion Systems; Male; Time Factors | 1988 |
Suppression of sleep-induced growth hormone secretion by anticholinergic agent abolishes dawn phenomenon.
Topics: Blood Glucose; Catecholamines; Circadian Rhythm; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glucagon; Growth Hormone; Humans; N-Methylscopolamine; Osmolar Concentration; Parasympatholytics; Scopolamine Derivatives; Sleep | 1988 |
Relationship between changes in GIP concentrations and changes in insulin and C-peptide concentrations after guar gum therapy.
Topics: Adult; C-Peptide; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Female; Galactans; Gastric Inhibitory Polypeptide; Glucagon; Humans; Insulin; Lipids; Male; Mannans; Middle Aged; Plant Gums; Random Allocation | 1986 |
Diurnal plasma profiles of metabolite and hormone concentration in insulin-dependent diabetic patients during conventional insulin treatment and continuous subcutaneous insulin infusion. A controlled study.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Female; Glucagon; Glycerol; Growth Hormone; Humans; Hydroxybutyrates; Insulin; Insulin Infusion Systems; Lactates; Lactic Acid; Male; Prospective Studies; Random Allocation | 1987 |
939 other study(ies) available for glucagon and Autoimmune Diabetes
| Article | Year |
|---|---|
Low-Order Nonlinear Animal Model of Glucose Dynamics for a Bihormonal Intraperitoneal Artificial Pancreas.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 1; Disease Models, Animal; Glucagon; Glucose; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Pancreas, Artificial; Swine | 2022 |
ZT-01: A novel somatostatin receptor 2 antagonist for restoring the glucagon response to hypoglycaemia in type 1 diabetes.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Insulin; Rats; Receptors, Somatostatin | 2022 |
Assessment of Two Different Glucagon Assays in Healthy Individuals and Type 1 and Type 2 Diabetes Patients.
Topics: Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Glucagon; Humans; Radioimmunoassay | 2022 |
Increased Expression of Viral Sensor MDA5 in Pancreatic Islets and in Hormone-Negative Endocrine Cells in Recent Onset Type 1 Diabetic Donors.
Topics: Autoantibodies; Diabetes Mellitus, Type 1; Endocrine Cells; Glucagon; Glucagon-Secreting Cells; Humans; Insulin; Islets of Langerhans; Tissue Donors | 2022 |
Pharmacokinetics of glucagon after intravenous, intraperitoneal and subcutaneous administration in a pig model.
Topics: Administration, Intravenous; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Insulin; Insulin Infusion Systems; Swine | 2022 |
Sleep deprivation prevents counterregulatory adaptation to recurrent hypoglycaemia.
Topics: Adolescent; Adult; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Norepinephrine; Sleep Deprivation; Young Adult | 2022 |
Pharmacodynamics, pharmacokinetics, safety, and tolerability of a ready-to-use, room temperature, liquid stable glucagon administered via an autoinjector pen to youth with type 1 diabetes.
Topics: Adolescent; Blood Glucose; Diabetes Mellitus, Type 1; Drug Delivery Systems; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Temperature | 2022 |
The effect of glucagon on local subcutaneous blood flow in non-diabetic volunteers; a proof-of-concept study.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Injections, Subcutaneous; Insulin; Volunteers | 2022 |
Prenatal exposure to a mixture of PAHs causes the dysfunction of islet cells in adult male mice: Association with type 1 diabetes mellitus.
Topics: Animals; Diabetes Mellitus, Type 1; Female; Glucagon; Glucagon-Secreting Cells; Islets of Langerhans; Male; Mice; Polycyclic Aromatic Hydrocarbons; Pregnancy; Prenatal Exposure Delayed Effects | 2022 |
α Cell dysfunction in islets from nondiabetic, glutamic acid decarboxylase autoantibody-positive individuals.
Topics: Autoantibodies; Diabetes Mellitus, Type 1; Glucagon; Glucose; Glutamate Decarboxylase; Humans | 2022 |
Glucagon-receptor-antagonism-mediated β-cell regeneration as an effective anti-diabetic therapy.
Topics: Animals; Diabetes Mellitus, Type 1; Disease Models, Animal; Glucagon; Glucagon-Secreting Cells; Hyperglycemia; Insulin-Secreting Cells; Mice; Receptors, Glucagon | 2022 |
A Dual-Hormone Multicontroller for Artificial Pancreas Systems.
Topics: Algorithms; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Pancreas, Artificial | 2022 |
Dasiglucagon for treating severe hypoglycemia in patients with diabetes.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Insulin; Water | 2022 |
RhoA as a Signaling Hub Controlling Glucagon Secretion From Pancreatic α-Cells.
Topics: Actins; Animals; Calcium; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Ephrins; Glucagon; Glucagon-Secreting Cells; Glucose; Humans; Insulin; Islets of Langerhans; Ligands; Mice; Receptors, Eph Family; rhoA GTP-Binding Protein | 2022 |
Not only for caregivers: intranasal glucagon for severe hypoglycaemia in a simulation study.
Topics: Blood Glucose; Caregivers; Child; Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Hypoglycemia; Insulin | 2022 |
Bihormonal Artificial Pancreas With Closed-Loop Glucose Control vs Current Diabetes Care After Total Pancreatectomy: A Randomized Clinical Trial.
Topics: Adult; Blood Glucose; Blood Glucose Self-Monitoring; Cross-Over Studies; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemia; Insulin; Male; Middle Aged; Pancreas, Artificial; Pancreatectomy; Penicillin G; Quality of Life | 2022 |
[Nasal glucagon (Baqsimi®), new treatment for hypoglycaemic coma].
Topics: Adolescent; Adult; Blood Glucose; Child; Coma; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin | 2022 |
γ-aminobutyric acid modulates α-cell hyperplasia but not β-cell regeneration induced by glucagon receptor antagonism in type 1 diabetic mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; gamma-Aminobutyric Acid; Glucagon; Hyperplasia; Insulin; Insulin-Secreting Cells; Mice; Receptors, Glucagon; Regeneration | 2023 |
Characteristic changes in plasma glutamate levels and free amino acid profiles in Japanese patients with type 1 diabetes mellitus.
Topics: Amino Acids; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; East Asian People; Glucagon; Glutamic Acid; Humans; Insulin | 2023 |
When insulin isn't enough: targeting glucagon in type 1 diabetes.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Humans; Insulin | 2022 |
Alpha cell dysfunction in type 1 diabetes is independent of a senescence program.
Topics: Animals; Biomarkers; Diabetes Mellitus, Type 1; Glucagon; Glucagon-Secreting Cells; Humans; Insulin; Mice; Mice, Inbred NOD | 2022 |
Glucose-responsive microneedle patch for closed-loop dual-hormone delivery in mice and pigs.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Glucose; Hypoglycemia; Insulin; Insulin Infusion Systems; Mice; Polymers; Swine; Swine, Miniature | 2022 |
Restoring glutamate receptor signaling in pancreatic alpha cells rescues glucagon responses in type 1 diabetes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucagon; Glucagon-Secreting Cells; Humans; Hypoglycemia; Insulin; Mice; Receptors, Glutamate | 2022 |
Knowledge of School Nurses on the Basic Principles of Type 1 Diabetes Mellitus Self-Control and Treatment in Children.
Topics: Adolescent; Blood Glucose; Child; Cross-Sectional Studies; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; Health Knowledge, Attitudes, Practice; Humans; Nurses; Self-Control | 2022 |
Glucagon Prescribing and Costs Among U.S. Adults With Diabetes, 2011-2021.
Topics: Adult; Aged; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemia; Insulin, Short-Acting; Male; Medicare; Middle Aged; Retrospective Studies; United States | 2023 |
Integrated safety and efficacy analysis of dasiglucagon for the treatment of severe hypoglycaemia in individuals with type 1 diabetes.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulins | 2023 |
Human pancreatic capillaries and nerve fibers persist in type 1 diabetes despite beta cell loss.
Topics: Animals; Capillaries; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Secreting Cells; Humans; Islets of Langerhans; Mice; Nerve Fibers | 2023 |
Modeling the effect of glucagon on endogenous glucose production in type 1 diabetes: On the role of glucagon receptor dynamics.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Insulin; Receptors, Glucagon | 2023 |
'Didn't See the Need': Misperceptions about glucagon from the perspectives of people with diabetes and their caregivers.
Topics: Caregivers; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Insulin | 2023 |
Small molecule glucagon release inhibitors with activity in human islets.
Topics: Animals; Diabetes Mellitus, Type 1; Glucagon; Glucagon-Secreting Cells; Humans; Insulin; Islets of Langerhans | 2023 |
Short-term fasting lowers glucagon levels under euglycemic and hypoglycemic conditions in healthy humans.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Intermittent Fasting | 2023 |
Associations between glucagon prescribing, hospital admissions for hypoglycaemia and continuous glucose monitoring metrics in adults with type 1 diabetes.
Topics: Adult; Benchmarking; Blood Glucose; Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Hospitals; Humans; Hypoglycemia; Hypoglycemic Agents | 2023 |
Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes.
Topics: Adolescent; Diabetes Mellitus, Type 1; Glucagon; Glucagon-Secreting Cells; Glycation End Products, Advanced; Humans; Hypoglycemia; Ligands; Receptor for Advanced Glycation End Products | 2023 |
Comparison of Intranasal and Injectable Glucagon Administration Among Pediatric Population Responders.
Topics: Administration, Intranasal; Adolescent; Child; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia | 2023 |
Type 1 and Type 2 Diabetes Mellitus: Commonalities, Differences and the Importance of Exercise and Nutrition.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Humans; Insulin | 2023 |
Greater Suppression of Glucagon, Lipolysis, and Ketogenesis with Insulin Glargine U300 as Compared with Glargine U100 in Type 1 Diabetes Mellitus.
Topics: Adult; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemic Agents; Insulin Glargine; Lipolysis; Middle Aged | 2020 |
Consistency of plasma glucagon levels in patients with type 1 diabetes after a 1-year period.
Topics: Adult; Asian People; Blood Urea Nitrogen; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Japan; Male | 2020 |
Glucose Sensor Accuracy After Subcutaneous Glucagon Injections Near to Sensor Site.
Topics: Abdomen; Adolescent; Adult; Aged; Blood Glucose; Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemic Agents; Injections, Subcutaneous; Insulin Infusion Systems; Male; Materials Testing; Middle Aged; Reference Values; Reproducibility of Results; Young Adult | 2020 |
Hypoglycemic Confidence in the Partners of Adults with Type 1 Diabetes.
Topics: Adult; Anxiety; Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 1; Factor Analysis, Statistical; Fear; Female; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Male; Middle Aged; Patient Satisfaction; Psychiatric Status Rating Scales; Qualitative Research; Regression Analysis; Reproducibility of Results; Self Report; Spouses; Stress, Psychological | 2020 |
Mini-doses of glucagon to prevent hypoglycemia in children with type 1 diabetes refusing food: a case series.
Topics: Blood Glucose; Blood Glucose Self-Monitoring; Child; Child, Preschool; Diabetes Mellitus, Type 1; Eating; Female; Glucagon; Humans; Hypoglycemia; Insulin; Insulin Infusion Systems; Male; Retrospective Studies | 2020 |
UCP1-independent glucose-lowering effect of leptin in type 1 diabetes: only in conditions of hypoleptinemia.
Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Blood Glucose; Corticosterone; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Eating; Glucagon; Gluconeogenesis; Humans; Insulin; Insulin-Like Growth Factor I; Leptin; Mice; Mice, Knockout; Oxygen Consumption; Peptides; Pyruvic Acid; Receptor, Insulin; Transcriptome; Uncoupling Protein 1 | 2020 |
Inhibition of sodium glucose cotransporter-2 affects HbA1c levels in people with insulin-dependent diabetes mellitus and differing levels of glucagon.
Topics: Aged; Aged, 80 and over; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 1; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Female; Glucagon; Glycated Hemoglobin; Humans; Male; Middle Aged; Sodium-Glucose Transporter 2 Inhibitors; Treatment Outcome | 2020 |
Beginning of a new era in glucagon research: Breakthrough by the new glucagon assay.
Topics: Biological Assay; Biomarkers; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Secreting Cells; Humans; Prognosis | 2020 |
Blood glucose regulation and control of insulin and glucagon infusion using single model predictive control for type 1 diabetes mellitus.
Topics: Algorithms; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Models, Biological; Pancreas; Risk | 2020 |
Functional β-Cell Differentiation of Small-Tail Han Sheep Pancreatic Mesenchymal Stem Cells and the Therapeutic Potential in Type 1 Diabetic Mice.
Topics: Animals; Blood Glucose; Body Weight; C-Peptide; Cell Differentiation; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Sheep | 2020 |
New drug hope for diabetes mellitus.
Topics: Carrier Proteins; Diabetes Mellitus, Type 1; Glucagon; Humans | 2020 |
Protein ingestion can significantly affect glucagon secretion along with blood urea nitrogen alteration in type 1 diabetes.
Topics: Blood Urea Nitrogen; Diabetes Mellitus, Type 1; Glucagon; Humans; Proteins | 2021 |
Ghrelin Protects Against Insulin-Induced Hypoglycemia in a Mouse Model of Type 1 Diabetes Mellitus.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Epinephrine; Ghrelin; Glucagon; Hypoglycemia; Insulin; Mice; Mice, Knockout; Norepinephrine | 2020 |
Pancreatic Alpha-Cells Contribute Together With Beta-Cells to CXCL10 Expression in Type 1 Diabetes.
Topics: Animals; Chemokine CXCL10; Diabetes Mellitus, Type 1; Glucagon; Glucagon-Secreting Cells; Humans; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Mice; Mice, Inbred C57BL; Mice, Inbred NOD | 2020 |
Glucagon in type 1 diabetes patients receiving SGLT2 inhibitors: A Friend or Foe?
Topics: Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemic Agents; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2021 |
Dual self-regulated delivery of insulin and glucagon by a hybrid patch.
Topics: Animals; Blood Glucose; Delayed-Action Preparations; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Combinations; Drug Compounding; Drug Delivery Systems; Drug Liberation; Drug Overdose; Glucagon; Humans; Hypoglycemic Agents; Insulin; Male; Mice; Polymerization; Solubility; Streptozocin; Transdermal Patch | 2020 |
Reversal of autoimmunity by mixed chimerism enables reactivation of β cells and transdifferentiation of α cells in diabetic NOD mice.
Topics: Animals; Autoimmunity; Blood Glucose; Cell Transdifferentiation; Chimerism; Diabetes Mellitus, Type 1; Epidermal Growth Factor; Female; Gastrins; Gene Expression Regulation; Glucagon; Glucagon-Secreting Cells; Insulin; Insulin-Secreting Cells; Mesenchymal Stem Cells; Mice; Mice, Inbred NOD; Precursor Cells, B-Lymphoid; Regeneration | 2020 |
Amylase-Dependent Regulation of Glucose Metabolism and Insulin/Glucagon Secretion in the Streptozotocin-Induced Diabetic Pig Model and in a Rat Pancreatic Beta-Cell Line, BRIN-BD11.
Topics: Amylases; Animals; Blood Glucose; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucose Tolerance Test; Infusions, Intravenous; Insulin; Insulin-Secreting Cells; Rats; Secretory Pathway; Streptozocin; Sus scrofa; Time Factors | 2020 |
Perceptions and expectations of adults with type 1 diabetes for the use of artificial pancreas systems with and without glucagon addition: Results of an online survey.
Topics: Adult; Diabetes Mellitus, Type 1; Female; Glucagon; Health Care Surveys; Health Knowledge, Attitudes, Practice; Humans; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Internet; Male; Middle Aged; Pancreas, Artificial; Patient Acceptance of Health Care; Patient Preference; Quality of Life; Quebec | 2021 |
Impact of glucagon response on early postprandial glucose excursions irrespective of residual β-cell function in type 1 diabetes: A cross-sectional study using a mixed meal tolerance test.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin-Secreting Cells; Male; Meals; Middle Aged; Prospective Studies | 2021 |
An Evaluation of Glucagon Injection Anxiety and Its Association with the Fear of Hypoglycemia among the Parents of Children with Type 1 Diabetes
Topics: Adolescent; Anxiety; Biomarkers; Blood Glucose; Caregivers; Child; Child, Preschool; Diabetes Mellitus, Type 1; Fear; Female; Glucagon; Health Knowledge, Attitudes, Practice; Humans; Hypoglycemia; Hypoglycemic Agents; Injections, Intramuscular; Male; Parents; Pilot Projects; Surveys and Questionnaires | 2021 |
Glucagon use by U.S. adults with type 1 and type 2 diabetes.
Topics: Adult; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Retrospective Studies; United States | 2021 |
Glucagon blockade restores functional β-cell mass in type 1 diabetic mice and enhances function of human islets.
Topics: Animals; Antibodies, Monoclonal; Blood Glucose; C-Peptide; Cell Lineage; Cell Transdifferentiation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Gene Expression; Glucagon; Glucagon-Secreting Cells; Humans; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Islets of Langerhans Transplantation; Mice; Mice, Inbred NOD; Organ Size; Receptors, Glucagon; Treatment Outcome | 2021 |
Transdermal delivery of a somatostatin receptor type 2 antagonist using microneedle patch technology for hypoglycemia prevention.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Delivery Systems; Glucagon; Humans; Hypoglycemia; Insulin; Needles; Polymers; Rats; Receptors, Somatostatin; Technology; Transdermal Patch | 2022 |
Parent and patient knowledge of nasal glucagon use and efficacy in a large cohort of Italian children and adolescents with type 1 diabetes.
Topics: Adolescent; Child; Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Italy; Parents | 2021 |
Performance of the Insulin-Only iLet Bionic Pancreas and the Bihormonal iLet Using Dasiglucagon in Adults With Type 1 Diabetes in a Home-Use Setting.
Topics: Adult; Bionics; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Pancreas; Pancreas, Artificial | 2021 |
Beneficial effects of physical exercise for β-cell maintenance in a type 1 diabetes mellitus animal model.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucagon; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Mice | 2021 |
Lack of Improvement in Insulin Sensitivity After Pancreas Transplantation in Recipients With a High Level of Calcineurin Inhibitors.
Topics: Adult; Blood Glucose; Calcineurin Inhibitors; Cyclosporine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Kaplan-Meier Estimate; Male; Middle Aged; Pancreas Transplantation; Tacrolimus | 2021 |
Dasiglucagon Hydrochloride.
Topics: Diabetes Mellitus, Type 1; Glucagon; Humans | 2021 |
C-peptide enhances glucagon secretion in response to hyperinsulinemia under euglycemic and hypoglycemic conditions.
Topics: Animals; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Dogs; Female; Glucagon; Hyperinsulinism; Hypoglycemia; Hypoglycemic Agents; Male | 2021 |
Glucagon in treatment of hypoglycemia - novelties.
Topics: Administration, Intranasal; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Insulin | 2021 |
β Cells Persist in T1D Pancreata Without Evidence of Ongoing β-Cell Turnover or Neogenesis.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Cell Transdifferentiation; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucagon; Glucagon-Secreting Cells; Humans; In Situ Nick-End Labeling; Infant; Infant, Newborn; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Ki-67 Antigen; Male; Middle Aged; Pancreas; Regeneration; Time Factors; Young Adult | 2017 |
Design of a dual-hormone model predictive control for artificial pancreas with exercise model.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Models, Biological; Pancreas, Artificial | 2016 |
Virgin Beta Cells Persist throughout Life at a Neogenic Niche within Pancreatic Islets.
Topics: Adult; Aging; Cell Differentiation; Cell Transdifferentiation; Cellular Microenvironment; Diabetes Mellitus, Type 1; Gene Expression Profiling; Glucagon; Glucagon-Secreting Cells; Humans; Insulin; Insulin-Secreting Cells; Tissue Donors; Transcription, Genetic; Urocortins | 2017 |
Mesenchymal stem cells and differentiated insulin producing cells are new horizons for pancreatic regeneration in type I diabetes mellitus.
Topics: Animals; Blood Glucose; Cell Differentiation; Cell- and Tissue-Based Therapy; Diabetes Mellitus, Type 1; Female; Gene Expression Regulation; Glucagon; Glucose Transporter Type 2; Homeodomain Proteins; Insulin; Insulin-Secreting Cells; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Pancreas; Rats; Regeneration; Trans-Activators | 2017 |
Faster Use and Fewer Failures with Needle-Free Nasal Glucagon Versus Injectable Glucagon in Severe Hypoglycemia Rescue: A Simulation Study.
Topics: Administration, Intranasal; Blood Glucose; Caregivers; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Injections; Manikins | 2017 |
Acute bout of exercise induced prolonged muscle glucose transporter-4 translocation and delayed counter-regulatory hormone response in type 1 diabetes.
Topics: Animals; Blood Glucose; Catecholamines; Diabetes Mellitus, Type 1; Disease Models, Animal; Glucagon; Glucose Transporter Type 4; Glucose-6-Phosphate; Insulin; Male; Physical Conditioning, Animal; Protein Transport; Rats; Rats, Wistar; Signal Transduction | 2017 |
Cross-Validation of a Glucose-Insulin-Glucagon Pharmacodynamics Model for Simulation Using Data From Patients With Type 1 Diabetes.
Topics: Adult; Biomarkers; Blood Glucose; Computer Simulation; Diabetes Mellitus, Type 1; Drug Dosage Calculations; Female; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Male; Middle Aged; Models, Biological; Reproducibility of Results; Treatment Outcome; Young Adult | 2017 |
Economic Model Predictive Control of Bihormonal Artificial Pancreas System Based on Switching Control and Dynamic R-parameter.
Topics: Algorithms; Biomarkers; Blood Glucose; Blood Glucose Self-Monitoring; Computer Simulation; Cost Savings; Cost-Benefit Analysis; Diabetes Mellitus, Type 1; Drug Costs; Glucagon; Humans; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Models, Biological; Models, Economic; Pancreas, Artificial; Postprandial Period; Predictive Value of Tests; Signal Processing, Computer-Assisted; Time Factors; Treatment Outcome | 2017 |
Stability of Commercially Available Glucagon Formulation for Dual-Hormone Artificial Pancreas Clinical Use.
Topics: Diabetes Mellitus, Type 1; Drug Stability; Glucagon; Humans; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Pancreas, Artificial | 2017 |
Persistence of Pancreatic Insulin mRNA Expression and Proinsulin Protein in Type 1 Diabetes Pancreata.
Topics: Adult; Diabetes Mellitus, Type 1; Female; Gene Expression Regulation; Glucagon; Humans; Insulin; Male; Pancreas; Pancreas, Exocrine; Proinsulin; Proprotein Convertase 1; RNA, Messenger; Young Adult | 2017 |
Relationship between Optimum Mini-doses of Glucagon and Insulin Levels when Treating Mild Hypoglycaemia in Patients with Type 1 Diabetes - A Simulation Study.
Topics: Adult; Blood Glucose; Computational Biology; Computer Simulation; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Monitoring; Expert Systems; Female; Glucagon; Hormone Replacement Therapy; Humans; Hypoglycemia; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Insulin Infusion Systems; Middle Aged; Models, Biological; Young Adult | 2018 |
A coordinated control strategy for insulin and glucagon delivery in type 1 diabetes.
Topics: Adolescent; Adult; Blood Glucose; Child; Computer Simulation; Diabetes Mellitus, Type 1; Drug Delivery Systems; Glucagon; Humans; Insulin; Pancreas, Artificial | 2017 |
Suppression of Extrapancreatic Glucagon by Octreotide May Reduce the Fasting and Postprandial Glucose Levels in a Diabetic Patient after Total Pancreatectomy.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Fasting; Female; Glucagon; Humans; Hyperglycemia; Hypoglycemia; Middle Aged; Octreotide; Pancreatectomy; Postprandial Period | 2017 |
Chronic Liraglutide Administration Fails to Suppress Postprandial Glucagon Levels in Type 1 Diabetic Islet Allograft Recipients With Graft Dysfunction.
Topics: Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemic Agents; Islets of Langerhans Transplantation; Liraglutide; Postprandial Period | 2018 |
Complete loss of insulin secretion capacity in type 1A diabetes patients during long-term follow up.
Topics: Adult; Age of Onset; Asian People; C-Peptide; Diabetes Mellitus, Type 1; Female; Follow-Up Studies; Glucagon; Humans; Insulin; Insulin Secretion; Japan; Male; Retrospective Studies; Young Adult | 2018 |
Altered Patterns of Early Metabolic Decompensation in Type 1 Diabetes During Treatment with a SGLT2 Inhibitor: An Insulin Pump Suspension Study.
Topics: Adolescent; Adult; Blood Glucose; Canagliflozin; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Humans; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Male; Middle Aged; Sodium-Glucose Transporter 2 Inhibitors; Young Adult | 2017 |
Differential associations of lower cardiac vagal tone with insulin resistance and insulin secretion in recently diagnosed type 1 and type 2 diabetes.
Topics: Adolescent; Adult; Aged; C-Peptide; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Clamp Technique; Heart; Heart Rate; Humans; Insulin; Insulin Resistance; Lipids; Male; Middle Aged; Vagus Nerve; Young Adult | 2018 |
Insulin deficiency with and without glucagon: A comparative study between total pancreatectomy and type 1 diabetes.
Topics: Aged; Case-Control Studies; Diabetes Mellitus, Type 1; Female; Follow-Up Studies; Glucagon; Humans; Insulin; Male; Middle Aged; Pancreatectomy; Prognosis; Retrospective Studies | 2018 |
Endogenous Reprogramming of Alpha Cells into Beta Cells, Induced by Viral Gene Therapy, Reverses Autoimmune Diabetes.
Topics: Alloxan; Animals; Blood Glucose; Cellular Reprogramming; Dependovirus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Gene Expression Profiling; Genetic Therapy; Glucagon; Glucagon-Secreting Cells; Homeodomain Proteins; Humans; Hyperglycemia; Insulin; Insulin-Secreting Cells; Lectins, C-Type; Mice, Inbred C57BL; Mice, SCID; Receptors, Immunologic; Trans-Activators | 2018 |
Highly Proliferative α-Cell-Related Islet Endocrine Cells in Human Pancreata.
Topics: Adolescent; Adult; Case-Control Studies; Cell Lineage; Cell Plasticity; Cell Proliferation; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Ghrelin; Glucagon; Glucagon-Secreting Cells; Homeodomain Proteins; Humans; Infant; Infant, Newborn; Islets of Langerhans; Ki-67 Antigen; Male; Pancreatic Polypeptide; Somatostatin; SOX9 Transcription Factor; Transcription Factors; Young Adult | 2018 |
Impact of C-Peptide Status on the Response of Glucagon and Endogenous Glucose Production to Induced Hypoglycemia in T1DM.
Topics: Adult; Awareness; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Drug Administration Schedule; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Humans; Hypoglycemia; Insulin; Male; Middle Aged; Norepinephrine; Young Adult | 2018 |
Vildagliptin/pioglitazone combination improved the overall glycemic control in type I diabetic rats.
Topics: Adamantane; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Glucagon; Glutathione; Glycated Hemoglobin; Insulin; Male; Malondialdehyde; Nitric Oxide; Nitriles; Pancreas; Pioglitazone; Pyrrolidines; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase; Thiazolidinediones; Vildagliptin | 2018 |
α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes.
Topics: Adolescent; Adult; Animals; Case-Control Studies; Cellular Reprogramming; Child; Diabetes Mellitus, Type 1; Female; Gene Expression Regulation; Glucagon; Glucagon-Secreting Cells; Humans; Insulin Secretion; Insulin-Secreting Cells; Male; Mice; Middle Aged; Phenotype; Tissue Donors; Transcription Factors; Young Adult | 2018 |
Adrenaline and cortisol levels are lower during nighttime than daytime hypoglycaemia in children with type 1 diabetes.
Topics: Blood Glucose; Child; Circadian Rhythm; Diabetes Mellitus, Type 1; Electrocardiography; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Male | 2018 |
Distribution of IL-1β immunoreactive cells in pancreatic biopsies from living volunteers with new-onset type 1 diabetes: comparison with donors without diabetes and with longer duration of disease.
Topics: Adolescent; Adult; Autoantibodies; Biopsy; Child; Child, Preschool; Cytokines; Diabetes Mellitus, Type 1; Female; Glucagon; Glucagon-Secreting Cells; Humans; Insulin; Insulin-Secreting Cells; Interleukin-1beta; Islets of Langerhans; Male; Pancreas; Time Factors; Tissue Donors; Young Adult | 2018 |
Conventional insulin pump therapy in two neonatal diabetes patients harboring the homozygous PTF1A enhancer mutation: Need for a novel approach for the management of neonatal diabetes.
Topics: Diabetes Mellitus, Type 1; Glucagon; Homozygote; Humans; Hypoglycemia; Infant, Newborn; Insulin Infusion Systems; Male; Mutation; Transcription Factors | 2017 |
Short-term changes in pancreatic α-cell function after the onset of fulminant type 1 diabetes.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Glucagon-Secreting Cells; Humans | 2018 |
Dysregulated plasma glucagon levels in Japanese young adult type 1 diabetes patients.
Topics: Adult; Asian People; Diabetes Mellitus, Type 1; Enzyme-Linked Immunosorbent Assay; Female; Glucagon; Humans; Hypoglycemia; Japan; Male | 2019 |
Associations of serum glucagon levels with glycemic variability in type 1 diabetes with different disease durations.
Topics: Adolescent; Adult; Blood Glucose; Blood Glucose Self-Monitoring; C-Peptide; Diabetes Mellitus, Type 1; Fasting; Female; Glucagon; Humans; Insulin; Male; Middle Aged; Time Factors; Young Adult | 2018 |
GLUCAGON PRESCRIPTIONS FOR DIABETES PATIENTS AFTER EMERGENCY DEPARTMENT VISITS FOR HYPOGLYCEMIA.
Topics: Adult; Aged; Aged, 80 and over; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Emergencies; Emergency Service, Hospital; Female; Glucagon; Hospitalization; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Middle Aged; Practice Patterns, Physicians'; Retrospective Studies | 2018 |
[Needs of schoolchildren with type 1 diabetes in Extremadura: Family perceptions].
Topics: Adolescent; Blood Glucose; Blood Glucose Self-Monitoring; Child; Child, Preschool; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Family; Female; Glucagon; Humans; Hypoglycemic Agents; Insulin; Male; Schools; Spain; Surveys and Questionnaires | 2019 |
Impaired glucagon secretion in patients with fulminant type 1 diabetes mellitus.
Topics: Adult; Aged; Aged, 80 and over; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Male; Middle Aged | 2019 |
The prescription rates of glucagon for hypoglycemia by pediatricians and physicians are low in Japan.
Topics: Adult; Child; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Drug Prescriptions; Female; Glucagon; Health Care Surveys; Humans; Hypoglycemia; Japan; Male; Practice Patterns, Physicians' | 2019 |
"Preserved" glucagon secretion in fulminant type 1 diabetes.
Topics: Adult; Aged; Diabetes Mellitus, Type 1; Glucagon; Glucagon-Secreting Cells; Humans; Insulin-Secreting Cells; Middle Aged | 2019 |
Early Clinical Indicators of Addison Disease in Adults With Type 1 Diabetes: A Nationwide, Observational, Cohort Study.
Topics: Addison Disease; Adult; Case-Control Studies; Cohort Studies; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Drug Prescriptions; Female; Glucagon; Hospitalization; Humans; Hypoglycemia; Hypoglycemic Agents; Infections; Male; Prodromal Symptoms; Prognosis; Registries; Sweden | 2019 |
Response to "Preserved" glucagon secretion in fulminant type 1 diabetes.
Topics: Arginine; Diabetes Mellitus, Type 1; Enzyme-Linked Immunosorbent Assay; Glucagon; Humans; Radioimmunoassay | 2019 |
Inappropriate glucagon and GLP-1 secretion in individuals with long-standing type 1 diabetes: effects of residual C-peptide.
Topics: Adult; Area Under Curve; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Glucose Tolerance Test; Humans; Incretins; Insulin; Insulin-Secreting Cells; Male; Young Adult | 2019 |
The characteristics of blood glucose fluctuations in patients with fulminant type 1 diabetes mellitus in the stable stage.
Topics: Adult; Blood Glucose; Blood Glucose Self-Monitoring; C-Peptide; Case-Control Studies; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Reference Values; Retrospective Studies; Statistics, Nonparametric | 2018 |
Nasal Glucagon Versus Injectable Glucagon for Severe Hypoglycemia: A Cost-Offset and Budget Impact Analysis.
Topics: Administration, Intranasal; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Gastrointestinal Agents; Glucagon; Humans; Hypoglycemia; Injections; Models, Economic | 2019 |
Long-Term Safety and Tolerability of Dasiglucagon, a Stable-in-Solution Glucagon Analogue.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 1; Dogs; Glucagon; Humans; Hypoglycemic Agents; Kidney; Liver; Rats; Treatment Outcome | 2019 |
Noninvasive diagnosis of recurrent autoimmune type 1 diabetes after islet cell transplantation.
Topics: Biomarkers; Blood Glucose; Diabetes Mellitus, Type 1; Exosomes; Glucagon; Glutamate Decarboxylase; Humans; Insulin; Islets of Langerhans Transplantation; Male; Middle Aged; Recurrence; Retrospective Studies; RNA, Messenger | 2019 |
Optimal regulation of blood glucose level in Type I diabetes using insulin and glucagon.
Topics: Algorithms; Blood Glucose; Diabetes Mellitus, Type 1; Drug Delivery Systems; Glucagon; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Nonlinear Dynamics; Postprandial Period; Risk | 2019 |
Glucagon receptor antagonism increases mouse pancreatic δ-cell mass through cell proliferation and duct-derived neogenesis.
Topics: Animals; Animals, Newborn; Antibodies, Monoclonal; Cell Proliferation; Cell Shape; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemic Agents; Insulin; Mice, Inbred C57BL; Receptors, Glucagon; Somatostatin; Somatostatin-Secreting Cells | 2019 |
Glucagon secretions are impaired in patients with fulminant type 1 diabetes.
Topics: Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Humans; Islets of Langerhans; Prognosis | 2019 |
Current view of treatment of hypoglycemia.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin | 2019 |
Glucose-Responsive Composite Microneedle Patch for Hypoglycemia-Triggered Delivery of Native Glucagon.
Topics: Animals; Blood Glucose; Cross-Linking Reagents; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Liberation; Gels; Glucagon; Humans; Hyaluronic Acid; Hypoglycemia; Hypoglycemic Agents; Insulin; Methacrylates; Needles; Photochemical Processes; Polymerization; Rats; Transdermal Patch | 2019 |
A statistical virtual patient population for the glucoregulatory system in type 1 diabetes with integrated exercise model.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Insulin; Kinetics; Male; Middle Aged; Models, Biological | 2019 |
Residual C-peptide in patients with Type 1 diabetes and multiethnic backgrounds.
Topics: Adolescent; Adult; C-Peptide; Diabetes Mellitus, Type 1; Epidemiologic Methods; Female; Glucagon; Humans; Luminescence; Male; Sex Factors; Time Factors; Young Adult | 2013 |
Reprogramming adult human dermal fibroblasts to islet-like cells by epigenetic modification coupled to transcription factor modulation.
Topics: Acetylation; Animals; Azacitidine; Blood Glucose; Cell Transdifferentiation; Cell- and Tissue-Based Therapy; Cellular Reprogramming; Depsipeptides; Diabetes Mellitus, Type 1; DNA Methylation; Fibroblasts; Glucagon; Histone Deacetylase Inhibitors; Histones; Homeodomain Proteins; Hormones; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Maf Transcription Factors; Mice; Skin; Trans-Activators | 2013 |
Somatostatin receptor type 2 antagonism improves glucagon counterregulation in biobreeding diabetic rats.
Topics: Animals; Catecholamines; Corticosterone; Diabetes Mellitus, Type 1; Glucagon; Glucagon-Secreting Cells; Glucose Clamp Technique; Humans; Insulin; Insulin Secretion; Male; Pancreas; Peptides, Cyclic; Prediabetic State; Rats; Receptors, Somatostatin; Somatostatin | 2013 |
A mixed mirror-image DNA/RNA aptamer inhibits glucagon and acutely improves glucose tolerance in models of type 1 and type 2 diabetes.
Topics: Animals; Aptamers, Nucleotide; Blood Glucose; Body Weight; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Fasting; Glucagon; Glucose Tolerance Test; Humans; Kinetics; Male; Mice; Mice, Inbred BALB C; RNA | 2013 |
Glucagon underutilized among type 1 diabetes mellitus patients in Japan.
Topics: Adult; Aged; Confidence Intervals; Diabetes Complications; Diabetes Mellitus, Type 1; Drug Utilization; Female; Gastrointestinal Agents; Glucagon; Health Knowledge, Attitudes, Practice; Humans; Hypoglycemia; Japan; Logistic Models; Male; Middle Aged; Odds Ratio; Surveys and Questionnaires | 2013 |
Leptin action in the ventromedial hypothalamic nucleus is sufficient, but not necessary, to normalize diabetic hyperglycemia.
Topics: Animals; Diabetes Mellitus, Type 1; Glucagon; Glucagon-Secreting Cells; Gluconeogenesis; Hyperglycemia; Hypoglycemic Agents; Infusions, Intraventricular; Injections, Intraventricular; Leptin; Liver; Male; Mice; Mice, Knockout; Nerve Tissue Proteins; Neurons; Rats; Rats, Wistar; Receptors, Leptin; Recombinant Proteins; Signal Transduction; Ventromedial Hypothalamic Nucleus | 2013 |
The incidence of severe hypoglycaemia in pregnant women with type 1 diabetes mellitus can be reduced with unchanged HbA1c levels and pregnancy outcomes in a routine care setting.
Topics: Blood Glucose; Blood Glucose Self-Monitoring; Cohort Studies; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Glycated Hemoglobin; Humans; Hypoglycemia; Insulin; Pregnancy; Pregnancy Outcome | 2013 |
A composite model of glucagon-glucose dynamics for in silico testing of bihormonal glucose controllers.
Topics: Algorithms; Blood Glucose; Blood Glucose Self-Monitoring; Computational Biology; Computer Simulation; Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Insulin Infusion Systems; Models, Biological | 2013 |
Pharmacokinetics modeling of exogenous glucagon in type 1 diabetes mellitus patients.
Topics: Adult; Algorithms; Bayes Theorem; Computer Simulation; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Monitoring, Physiologic; Pancreas, Artificial | 2013 |
Glycaemic instability correlates with a hyperglucagonaemic response in patients with type 1 diabetes without residual beta-cell function.
Topics: Adult; Area Under Curve; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Male; Middle Aged | 2013 |
Insulin's sidekicks. Developing alternative medications for type 1 diabetes.
Topics: Administration, Oral; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemic Agents; Insulin; Islet Amyloid Polypeptide | 2013 |
The inactivation of Arx in pancreatic α-cells triggers their neogenesis and conversion into functional β-like cells.
Topics: Animals; Cell Differentiation; Diabetes Mellitus, Type 1; Disease Models, Animal; Gene Expression Regulation; Glucagon; Glucagon-Secreting Cells; Homeodomain Proteins; Humans; Insulin-Secreting Cells; Islets of Langerhans; Mice, Transgenic; Paired Box Transcription Factors; Transcription Factors | 2013 |
IL-2 immunotherapy reveals potential for innate beta cell regeneration in the non-obese diabetic mouse model of autoimmune diabetes.
Topics: Animals; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Glucagon; Immunotherapy; Insulin; Insulin-Secreting Cells; Interleukin-2; Mice; Mice, Inbred NOD; Regeneration; T-Lymphocytes, Regulatory | 2013 |
Feasibility of a portable bihormonal closed-loop system to control glucose excursions at home under free-living conditions for 48 hours.
Topics: Administration, Metronomic; Adult; Algorithms; Blood Glucose; Blood Glucose Self-Monitoring; Calibration; Diabetes Mellitus, Type 1; Feasibility Studies; Female; Glucagon; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Male; Middle Aged; Monitoring, Ambulatory; Telemedicine | 2014 |
Glucagon response to oral glucose challenge in type 1 diabetes: lack of impact of euglycemia.
Topics: Blood Glucose; Carbohydrate Metabolism, Inborn Errors; Diabetes Mellitus, Type 1; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Tolerance Test; Glycerol Kinase; Humans; Hypoadrenocorticism, Familial; Incretins; Male; Middle Aged | 2014 |
Systematically in silico comparison of unihormonal and bihormonal artificial pancreas systems.
Topics: Algorithms; Blood Glucose; Computer Simulation; Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Pancreas, Artificial; User-Computer Interface | 2013 |
Pharmacokinetics of insulin aspart and glucagon in type 1 diabetes during closed-loop operation.
Topics: Adult; Body Composition; Body Mass Index; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemic Agents; Infusions, Subcutaneous; Insulin Aspart; Metabolic Clearance Rate; Middle Aged; Retrospective Studies | 2013 |
Progressive change of intra-islet GLP-1 production during diabetes development.
Topics: Algorithms; Animals; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Progression; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Immunohistochemistry; Islets of Langerhans; Male; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Mutant Strains; Prediabetic State; Proprotein Convertase 1; Up-Regulation | 2014 |
Evolution of abnormal plasma glucagon responses to mixed-meal feedings in youth with type 1 diabetes during the first 2 years after diagnosis.
Topics: Adolescent; Biomarkers; Blood Glucose; Case-Control Studies; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemia; Male; Meals; Postprandial Period | 2014 |
Struggles with clinical translation of immune intervention trials.
Topics: Chaperonin 60; Diabetes Mellitus, Type 1; Female; Food; Gastrointestinal Agents; Glucagon; Humans; Hypoglycemic Agents; Male; Peptide Fragments | 2014 |
Closed-loop artificial pancreas systems: physiological input to enhance next-generation devices.
Topics: Algorithms; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Eating; Exercise; Glucagon; Gonadal Steroid Hormones; Humans; Hyperglycemia; Hypoglycemia; Insulin; Insulin Infusion Systems; Pancreas, Artificial; Stress, Psychological | 2014 |
Utility of glucagon stimulation test in type 1 diabetes after pancreas transplantation.
Topics: C-Peptide; Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Pancreas Transplantation | 2014 |
Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucagon; Gluconeogenesis; Hypothalamo-Hypophyseal System; Insulin; Leptin; Lipolysis; Pituitary-Adrenal System; Rats | 2014 |
Defective glucagon secretion during hypoglycemia after intrahepatic but not nonhepatic islet autotransplantation.
Topics: Adult; Arginine; Autografts; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemia; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Liver; Male; Pancreatectomy; Pancreatic Diseases; Pancreatic Ducts; Pancreatitis; Treatment Outcome | 2014 |
Islet remodeling in female mice with spontaneous autoimmune and streptozotocin-induced diabetes.
Topics: Animals; Blood Glucose; Cell Proliferation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Immunohistochemistry; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Mice, Inbred BALB C; Mice, Inbred NOD; Somatostatin | 2014 |
Glucagon in the artificial pancreas: supply and marketing challenges.
Topics: Adult; Diabetes Mellitus, Type 1; Drug Approval; Drug Costs; Drug Delivery Systems; Glucagon; Health Care Sector; Humans; Marketing of Health Services; Pancreas, Artificial; United States | 2015 |
Comment on Kramer et al. Glucagon response to oral glucose challenge in type 1 diabetes: lack of impact of euglycemia. Diabetes Care 2014;37:1076-1082.
Topics: Blood Glucose; Carbohydrate Metabolism, Inborn Errors; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Glycerol Kinase; Humans; Male | 2014 |
Response to comment on Kramer et al. Glucagon response to oral glucose challenge in type 1 diabetes: lack of impact of euglycemia. Diabetes Care 2014;37:1076-1082.
Topics: Blood Glucose; Carbohydrate Metabolism, Inborn Errors; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Glycerol Kinase; Humans; Male | 2014 |
Intravenous glucagon in a deliberate insulin overdose in an adolescent with type 1 diabetes mellitus.
Topics: Administration, Intravenous; Adolescent; Blood Glucose; Diabetes Mellitus, Type 1; Drug Overdose; Glucagon; Hormones; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin, Long-Acting; Male | 2016 |
Comment on Kramer et al. Glucagon response to oral glucose challenge in type 1 diabetes: lack of impact of euglycemia. Diabetes Care 2014;37:1076-1082.
Topics: Blood Glucose; Carbohydrate Metabolism, Inborn Errors; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Glycerol Kinase; Humans; Male | 2014 |
Response to comment on Kramer et al. Glucagon response to oral glucose challenge in type 1 diabetes: lack of impact of euglycemia. Diabetes Care 2014;37:1076-1082.
Topics: Blood Glucose; Carbohydrate Metabolism, Inborn Errors; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Glycerol Kinase; Humans; Male | 2014 |
A novel, stable, aqueous glucagon formulation using ferulic acid as an excipient.
Topics: Animals; Blood Glucose; Coumaric Acids; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Delivery Systems; Drug Stability; Excipients; Glucagon; Humans; Infusion Pumps; Pharmaceutical Solutions; Swine; Water | 2015 |
Development of stable liquid glucagon formulations for use in artificial pancreas.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Dogs; Drug Delivery Systems; Drug Stability; Female; Glucagon; Humans; Male; Pancreas, Artificial; Pharmaceutical Solutions; Swine | 2015 |
Possible contribution of taurine to distorted glucagon secretion in intra-islet insulin deficiency: a metabolome analysis using a novel α-cell model of insulin-deficient diabetes.
Topics: Animals; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Gene Knockdown Techniques; Glucagon; Glucagon-Secreting Cells; Male; Mice; Mice, Inbred ICR; Receptor, Insulin; Taurine | 2014 |
When you come to a fork in the road, take it!
Topics: Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Pancreas, Artificial | 2015 |
Morphological assessment of pancreatic islet hormone content following aerobic exercise training in rats with poorly controlled Type 1 diabetes mellitus.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucagon; Glucose Transporter Type 4; Insulin; Islets of Langerhans; Male; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Receptor, Insulin | 2014 |
Diabetes: Artificial pancreas--first head-to-head comparison of dual-hormone and single-hormone systems.
Topics: Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Pancreas, Artificial | 2015 |
The influence of glucagon on postprandial hyperglycaemia in children 5 years after onset of type 1 diabetes.
Topics: Adolescent; Age of Onset; Biomarkers; Blood Glucose; Child; Denmark; Diabetes Mellitus, Type 1; Female; Follow-Up Studies; Glucagon; Glycated Hemoglobin; Humans; Hyperglycemia; Insulin-Secreting Cells; Male; Multivariate Analysis; Prospective Studies; Time Factors | 2015 |
Glucagon receptor antibody completely suppresses type 1 diabetes phenotype without insulin by disrupting a novel diabetogenic pathway.
Topics: Animals; Antibodies, Monoclonal; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Insulin; Mice; Mice, Inbred NOD; Paracrine Communication; Rats; Rats, Zucker; Receptors, Glucagon | 2015 |
Incretin and glucagon levels in adult offspring exposed to maternal diabetes in pregnancy.
Topics: Adolescent; Adult; Adult Children; Diabetes Mellitus, Type 1; Diabetes, Gestational; Female; Follow-Up Studies; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Humans; Male; Pregnancy; Prenatal Exposure Delayed Effects; Young Adult | 2015 |
The next best thing to a cure.
Topics: Diabetes Mellitus, Type 1; Glucagon; Hormones; Humans; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Inventions | 2015 |
Differential sequential patterns supporting insulin therapy of new-onset type 1 diabetes.
Topics: Algorithms; Blood Glucose; Circadian Rhythm; Data Mining; Datasets as Topic; Decision Support Systems, Clinical; Decision Support Techniques; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Drug Administration Schedule; Eating; Glucagon; Humans; Insulin; Insulin Secretion; Pancreas; Secretory Rate; Sleep | 2015 |
Pathway to artificial pancreas systems revisited: moving downstream.
Topics: Cost-Benefit Analysis; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Forecasting; Gastrointestinal Agents; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Pancreas, Artificial; Patient Satisfaction; Treatment Outcome | 2015 |
Short-term diabetic hyperglycemia suppresses celiac ganglia neurotransmission, thereby impairing sympathetically mediated glucagon responses.
Topics: Animals; Diabetes Mellitus, Type 1; Down-Regulation; Electric Stimulation; Ganglia, Sympathetic; Ganglionic Stimulants; Glucagon; Hyperglycemia; Islets of Langerhans; Male; Mutant Proteins; Nerve Tissue Proteins; Neurons; Nicotinic Agonists; Norepinephrine; Proto-Oncogene Proteins c-fos; Rats, Sprague-Dawley; Rats, Transgenic; Rats, Wistar; Receptors, Nicotinic; Synaptic Transmission; Wallerian Degeneration | 2015 |
Extreme Beta-Cell Deficiency in Pancreata of Dogs with Canine Diabetes.
Topics: Animals; Cell Proliferation; Diabetes Mellitus, Type 1; Dogs; Female; Glucagon; Hyperglycemia; Insulin; Insulin-Secreting Cells; Ketosis; Lymphocytes; Male; Organ Size | 2015 |
Is glucagon needed in type 1 diabetes?
Topics: Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Insulin; Insulin Infusion Systems; Male; Pancreas, Artificial | 2015 |
Insulin Delivery Into the Peripheral Circulation: A Key Contributor to Hypoglycemia in Type 1 Diabetes.
Topics: Administration, Intravenous; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Dogs; Glucagon; Glucose; Humans; Hypoglycemia; Insulin; Male; Portal Vein; Somatostatin | 2015 |
Sustained treatment with a stable long-acting oxyntomodulin analogue improves metabolic control and islet morphology in an experimental model of type 1 diabetes.
Topics: Animals; Apoptosis; Blood Glucose; Cell Proliferation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Eating; Gastrointestinal Hormones; Glucagon; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Mice; Oxyntomodulin; Pancreas | 2015 |
Nocturnal Glucose Metabolism in Type 1 Diabetes: A Study Comparing Single Versus Dual Tracer Approaches.
Topics: Adult; Blood Glucose; Blood Glucose Self-Monitoring; Circadian Rhythm; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hydrocortisone; Insulin; Male; Middle Aged; Sleep | 2015 |
Diabetes Is Reversed in a Murine Model by Marginal Mass Syngeneic Islet Transplantation Using a Subcutaneous Cell Pouch Device.
Topics: Animals; Bioartificial Organs; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Equipment Design; Glucagon; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Mice, Inbred BALB C; Microvessels; Neovascularization, Physiologic; Pancreas, Artificial; Time Factors; Transplantation, Isogeneic | 2015 |
Effect of Repeated Glucagon Doses on Hepatic Glycogen in Type 1 Diabetes: Implications for a Bihormonal Closed-Loop System.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Feedback, Physiological; Female; Glucagon; Hormones; Humans; Hypoglycemia; Insulin; Liver Glycogen; Male | 2015 |
Cathelicidin Antimicrobial Peptide: A Novel Regulator of Islet Function, Islet Regeneration, and Selected Gut Bacteria.
Topics: Aged; Animals; Antimicrobial Cationic Peptides; Bacterial Proteins; Calcium Signaling; Cathelicidins; Diabetes Mellitus, Type 1; Dysbiosis; Gastrointestinal Agents; Gastrointestinal Microbiome; Gene Expression Profiling; Germ-Free Life; Glucagon; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Intestinal Mucosa; Islets of Langerhans; Jejunum; Male; Mice, Inbred NOD; Peptide Fragments; Rats, Inbred Strains; Regeneration; Tissue Culture Techniques | 2015 |
Incorporating an Exercise Detection, Grading, and Hormone Dosing Algorithm Into the Artificial Pancreas Using Accelerometry and Heart Rate.
Topics: Actigraphy; Algorithms; Biomarkers; Blood Glucose; Computer Simulation; Diabetes Mellitus, Type 1; Drug Dosage Calculations; Energy Metabolism; Equipment Design; Exercise; Exercise Test; Glucagon; Heart Rate; Humans; Hypoglycemic Agents; Insulin; Linear Models; Models, Biological; Pancreas, Artificial; Predictive Value of Tests; Time Factors | 2015 |
GLUCAGON PRESCRIPTION PATTERNS IN PATIENTS WITH EITHER TYPE 1 OR 2 DIABETES WITH NEWLY PRESCRIBED INSULIN.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Practice Patterns, Physicians'; Retrospective Studies; Young Adult | 2016 |
Robust PBPK/PD-Based Model Predictive Control of Blood Glucose.
Topics: Algorithms; Blood Glucose; Computer Simulation; Decision Making, Computer-Assisted; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemic Agents; Insulin; Models, Biological; Models, Statistical; Monitoring, Physiologic; Pancreas, Artificial; Subcutaneous Tissue | 2016 |
Short-term glucagon stimulation test of C-peptide effect on glucose utilization in patients with type 1 diabetes mellitus.
Topics: Adult; Blood Glucose; C-Peptide; Case-Control Studies; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Humans; Male; Models, Statistical; Young Adult | 2015 |
Insulin Knockout Mice Have Extended Survival but Volatile Blood Glucose Levels on Leptin Therapy.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Cholesterol; Corticosterone; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Fatty Acids; Glucagon; Glycerol; Hyperglycemia; Hypoglycemia; Insulin; Leptin; Mice; Mice, Knockout; Peptides; Receptor, Insulin; Triglycerides | 2016 |
Nonaqueous, Mini-Dose Glucagon for Treatment of Mild Hypoglycemia in Adults With Type 1 Diabetes: A Dose-Seeking Study.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Drug Delivery Systems; Female; Gastrointestinal Agents; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Insulin Infusion Systems; Male; Random Allocation | 2016 |
Changes in obestatin gene and GPR39 receptor expression in peripheral tissues of rat models of obesity, type 1 and type 2 diabetes.
Topics: Analysis of Variance; Animals; Blood Glucose; Blotting, Western; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Gene Expression; Ghrelin; Glucagon; Insulin; Male; Obesity; Peptide Hormones; Rats, Wistar; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; Triglycerides | 2017 |
[In silico diabetology].
Topics: Computer Simulation; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucose; Humans; Insulin; Kinetics; Models, Biological; User-Computer Interface | 2016 |
The glucoregulatory response to high-intensity aerobic exercise following training in rats with insulin-treated type 1 diabetes mellitus.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Glycogen; Insulin; Liver; Male; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Sedentary Behavior | 2016 |
Human Type 1 Diabetes Is Characterized by an Early, Marked, Sustained, and Islet-Selective Loss of Sympathetic Nerves.
Topics: Adolescent; Adult; Autonomic Nervous System; Child; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Hypoglycemia; Immunohistochemistry; Islets of Langerhans; Male; Middle Aged; Pancreas; Sympathetic Nervous System; Young Adult | 2016 |
Effects of γ-Aminobutyric Acid A Receptor Activation on Counterregulatory Responses to Subsequent Exercise in Individuals With Type 1 Diabetes.
Topics: Adult; Alprazolam; Animals; Autonomic Nervous System; Benzodiazepines; Diabetes Mellitus, Type 1; Epinephrine; Female; gamma-Aminobutyric Acid; Glucagon; Humans; Hydrocortisone; Lipolysis; Male; Norepinephrine; Receptors, GABA-A | 2016 |
Formononetin exhibits anti-hyperglycemic activity in alloxan-induced type 1 diabetic mice.
Topics: Alloxan; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Glucagon; Hypoglycemic Agents; Insulin; Islets of Langerhans; Isoflavones; Liver; Liver Glycogen; Male; Mice | 2017 |
Modeling Glucagon Action in Patients With Type 1 Diabetes.
Topics: Algorithms; Bayes Theorem; Computer Simulation; Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Insulin Infusion Systems; Models, Biological; Pancreas, Artificial | 2017 |
Role of Dual-Hormone Closed-Loop Delivery System in the Future.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Drug Monitoring; Drug Therapy, Combination; Glucagon; Hormone Replacement Therapy; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Infusion Pumps; Insulin; Insulin Infusion Systems; Monitoring, Ambulatory; Randomized Controlled Trials as Topic | 2016 |
Comment on Rickels et al. Intranasal Glucagon for Treatment of Insulin-Induced Hypoglycemia in Adults With Type 1 Diabetes: A Randomized Crossover Noninferiority Study. Diabetes Care 2016;39:264-270.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin | 2016 |
Response to Comment on Rickels et al. Intranasal Glucagon for Treatment of Insulin-Induced Hypoglycemia in Adults With Type 1 Diabetes: A Randomized Crossover Noninferiority Study. Diabetes Care 2016;39:264-270.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Insulin | 2016 |
Glucagon-secretion inhibition using somatostatin: An old hormone for the treatment of diabetes-associated pancreatectomy.
Topics: Adult; Aged; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Male; Middle Aged; Pancreatectomy; Somatostatin | 2017 |
PAR2 regulates regeneration, transdifferentiation, and death.
Topics: Animals; Carbon Tetrachloride; Cell Death; Cell Lineage; Cell Proliferation; Cell Survival; Cell Transdifferentiation; Ceruletide; Diabetes Mellitus, Type 1; Extremities; Gene Expression Regulation; Glucagon; Homeodomain Proteins; Humans; Insulin; Insulin-Secreting Cells; Liver; Mice, Inbred C57BL; Mice, Knockout; Paired Box Transcription Factors; Pancreatitis; Receptor, PAR-2; Regeneration; Transcription Factors | 2016 |
Neu5Gc and α1-3 GAL Xenoantigen Knockout Does Not Affect Glycemia Homeostasis and Insulin Secretion in Pigs.
Topics: Animals; Antigens, Heterophile; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Galactose; Gene Knockout Techniques; Glucagon; Glucose; Homeostasis; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Neuraminic Acids; Pancreas; Purinergic P1 Receptor Antagonists; Swine; Theophylline; Transplantation, Heterologous | 2017 |
Converting Adult Pancreatic Islet α Cells into β Cells by Targeting Both Dnmt1 and Arx.
Topics: Adult; Aging; Calcium Signaling; Cell Lineage; Child; Child, Preschool; Diabetes Mellitus, Type 1; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Electrophysiological Phenomena; Female; Gene Deletion; Gene Expression Regulation; Glucagon; Glucagon-Secreting Cells; Glucose; Homeodomain Proteins; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Sequence Analysis, RNA; Single-Cell Analysis; Transcription Factors; Young Adult | 2017 |
Suppression of islet homeostasis protein thwarts diabetes mellitus progression.
Topics: Animals; Cell Line; Diabetes Mellitus, Type 1; Female; Glucagon; HLA-D Antigens; Homeodomain Proteins; Humans; Hyperglycemia; Islets of Langerhans; Male; Mice; Mice, Inbred NOD; Proteins; Trans-Activators | 2017 |
Paracrine GABA and insulin regulate pancreatic alpha cell proliferation in a mouse model of type 1 diabetes.
Topics: Animals; Blood Glucose; Cell Proliferation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Glucagon; Glucagon-Secreting Cells; Male; Mice; Mice, Inbred C57BL; Muscimol | 2017 |
Too much glucagon, too little insulin: time course of pancreatic islet dysfunction in new-onset type 1 diabetes.
Topics: Adolescent; Age of Onset; C-Peptide; Child; Child, Preschool; Diabetes Mellitus, Type 1; Eating; Fasting; Female; Follow-Up Studies; Glucagon; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male | 2008 |
Postnatal expansion of the pancreatic beta-cell mass is dependent on survivin.
Topics: Animals; Diabetes Mellitus, Type 1; Female; Gene Deletion; Glucagon; Immunohistochemistry; Inhibitor of Apoptosis Proteins; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Male; Mice; Mice, Inbred Strains; Mice, Transgenic; Microtubule-Associated Proteins; Repressor Proteins; Somatostatin; Survivin | 2008 |
The use of exenatide in islet transplant recipients with chronic allograft dysfunction: safety, efficacy, and metabolic effects.
Topics: Adult; Amyloid; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Exenatide; Feasibility Studies; Glucagon; Graft Rejection; Graft Survival; Humans; Hypoglycemic Agents; Immunosuppressive Agents; Insulin; Islet Amyloid Polypeptide; Islets of Langerhans Transplantation; Middle Aged; Peptides; Prospective Studies; Time Factors; Transplantation, Homologous; Treatment Outcome; Venoms | 2008 |
Mixed-meal tolerance test versus glucagon stimulation test for the assessment of beta-cell function in therapeutic trials in type 1 diabetes.
Topics: Adolescent; Adult; Age of Onset; Biomarkers; C-Peptide; Child; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diet, Diabetic; Fasting; Glucagon; Humans; Insulin-Secreting Cells; Racial Groups; Random Allocation; Sensitivity and Specificity | 2008 |
Effects of glucagon on islet beta cell function in patients with diabetes mellitus.
Topics: Adult; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Glycated Hemoglobin; Humans; Insulin; Islets of Langerhans; Male; Middle Aged | 2008 |
Protein and glutamine kinetics during counter-regulatory failure in type 1 diabetes.
Topics: Adult; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Gluconeogenesis; Glucose; Glucose Clamp Technique; Glutamine; Humans; Hypoglycemia; Insulin; Leucine; Male; Metabolic Clearance Rate | 2009 |
Gastric emptying and postprandial glucose excursions in adolescents with type 1 diabetes.
Topics: Adolescent; Amyloid; Blood Glucose; Diabetes Mellitus, Type 1; Gastric Emptying; Gastrointestinal Motility; Glucagon; Humans; Insulin; Islet Amyloid Polypeptide; Postprandial Period | 2008 |
Making insulin-deficient type 1 diabetic rodents thrive without insulin.
Topics: Alloxan; Animals; Diabetes Complications; Diabetes Mellitus, Type 1; Down-Regulation; Glucagon; Insulin; Insulin-Like Growth Factor I; Liver; Mice; Rats; Signal Transduction; STAT3 Transcription Factor; Streptozocin | 2008 |
A case of fulminant type 1 diabetes mellitus with exocrine pancreatic insufficiency and enhanced glucagon response to meal ingestion.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Exocrine Pancreatic Insufficiency; Glucagon; Humans; Insulin; Male; Middle Aged | 2008 |
Islet alpha cell number is maintained in microencapsulated islet transplantation.
Topics: Animals; Blood Glucose; Capsules; Cell Count; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; DNA; Glucagon; Glucagon-Secreting Cells; Hyperglycemia; Insulin; Insulin-Secreting Cells; Islets of Langerhans Transplantation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL | 2008 |
What is known, new and controversial about GLP-1? Minutes of the 1st European GLP-1 Club Meeting, Marseille, 28-29 May 2008.
Topics: Animals; Cell Differentiation; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; France; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; L Cells; Mice | 2008 |
[Pancreatic function assessment in type 1 diabetes mellitus patients according to disease duration].
Topics: Adolescent; C-Peptide; Chi-Square Distribution; Diabetes Mellitus, Type 1; Female; Glucagon; Glutamate Decarboxylase; Glycated Hemoglobin; Humans; Insulin; Insulin Secretion; Male; Pancreas; Time Factors; Young Adult | 2009 |
Hypothalamic AMP-activated protein kinase activation with AICAR amplifies counterregulatory responses to hypoglycemia in a rodent model of type 1 diabetes.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Disease Models, Animal; Enzyme Activation; Enzyme Activators; Epinephrine; Glucagon; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Microinjections; Rats; Rats, Inbred BB; Rats, Sprague-Dawley; Ribonucleotides; RNA Interference; RNA, Small Interfering; Time Factors; Ventromedial Hypothalamic Nucleus | 2009 |
Blunted counterregulatory hormone responses to hypoglycemia in young children and adolescents with well-controlled type 1 diabetes.
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Dietary Carbohydrates; Epinephrine; Glucagon; Glycated Hemoglobin; Hormones; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Hypoglycemic Agents; Insulin Infusion Systems; Norepinephrine | 2009 |
Beta-cell-mediated signaling predominates over direct alpha-cell signaling in the regulation of glucagon secretion in humans.
Topics: C-Peptide; Diabetes Mellitus, Type 1; Eating; Epinephrine; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Glucagon-Secreting Cells; Homeostasis; Humans; Hypoglycemic Agents; Insulin-Secreting Cells; Male; Reference Values; Signal Transduction; Sulfonylurea Compounds | 2009 |
Loss of islet sympathetic nerves and impairment of glucagon secretion in the NOD mouse: relationship to invasive insulitis.
Topics: Animals; Cyclophosphamide; Diabetes Mellitus, Type 1; Female; Glucagon; Hyperinsulinism; Islets of Langerhans; Male; Mice; Mice, Inbred NOD; Oxidopamine; Sympathetic Nervous System; Tyramine | 2009 |
ATP-sensitive K+ channel mediates the zinc switch-off signal for glucagon response during glucose deprivation.
Topics: Animals; Calcium Channels; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Glucagon-Secreting Cells; Humans; Hypoglycemia; Insulin; Insulin Secretion; KATP Channels; Male; Mice; Mice, Inbred C57BL; Nifedipine; Rats; Signal Transduction; Zinc | 2010 |
Impact of type 1 diabetes and insulin treatment on plasma levels and fractional synthesis rate of retinol-binding protein 4.
Topics: Adolescent; Adult; Blood Glucose; Blotting, Western; Child; Cytokines; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemic Agents; Insulin; Kinetics; Male; Retinol-Binding Proteins, Plasma; Young Adult | 2009 |
A case of recurrent type 1 diabetes mellitus with insulitis of transplanted pancreas in simultaneous pancreas-kidney transplantation from cardiac death donor.
Topics: Adult; Biopsy; Cadaver; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Glucagon; Graft Rejection; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Secretion; Kidney Transplantation; Pancreas Transplantation; Postoperative Complications; Recurrence; Renal Dialysis; Tissue Donors; Young Adult | 2010 |
System-level control to optimize glucagon counterregulation by switch-off of α-cell suppressing signals in β-cell deficiency.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Glucagon-Secreting Cells; Homeostasis; Insulin; Insulin-Secreting Cells; Models, Theoretical; Rats; Somatostatin | 2009 |
Skipping meals or carbohydrate-free meals in order to determine Basal insulin requirements in subjects with type 1 diabetes mellitus?
Topics: Adult; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 1; Diet, Diabetic; Dietary Proteins; Digestion; Dose-Response Relationship, Drug; Eating; Fasting; Feeding Behavior; Female; Glucagon; Glycated Hemoglobin; Humans; Insulin; Male; Middle Aged | 2010 |
Inappropriate glucagon response after oral compared with isoglycemic intravenous glucose administration in patients with type 1 diabetes.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Humans; Infusions, Intravenous; Male; Young Adult | 2010 |
Leptin therapy in insulin-deficient type I diabetes.
Topics: Adenylate Kinase; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Drug Implants; Gene Expression Regulation; Glucagon; Insulin; Leptin; Liver; Metabolome; Mice; Mice, Inbred NOD; Phosphorylation; Recombinant Proteins; RNA, Messenger; Triglycerides | 2010 |
Effect of glucagon-like peptide-1 on alpha- and beta-cell function in C-peptide-negative type 1 diabetic patients.
Topics: Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Humans; Hyperglycemia; Insulin-Secreting Cells; Serum Albumin | 2010 |
Detection of surreptitious administration of analog insulin to an 8-week-old infant.
Topics: C-Peptide; Diabetes Mellitus, Type 1; Diagnosis, Differential; Emergency Service, Hospital; Female; Glucagon; Humans; Hyperinsulinism; Hypoglycemia; Hypoglycemic Agents; Infant; Insulin; Insulin Aspart; Male; Munchausen Syndrome by Proxy; Pregnancy; Pregnancy in Diabetics; Recurrence | 2010 |
Optimal control of blood glucose: the diabetic patient or the machine?
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Pancreas, Artificial | 2010 |
Diabetes forum: Extreme makeover of pancreatic alpha-cells.
Topics: Animals; Cell Death; Cell Differentiation; Cell Lineage; Cell Proliferation; Cell Transdifferentiation; Diabetes Mellitus, Type 1; Diphtheria Toxin; Glucagon; Glucagon-Secreting Cells; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mice; Mice, Transgenic; Regeneration | 2010 |
Influence of plasma glucagon levels on glycemic control in children with type 1 diabetes.
Topics: Adolescent; Biomarkers; Blood Glucose; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Glycated Hemoglobin; Humans; Insulin-Secreting Cells; Japan; Male | 2011 |
Differentiation of human multipotent dermal fibroblasts into islet-like cell clusters.
Topics: Cell Culture Techniques; Cell Differentiation; Cells, Cultured; Clone Cells; Dermis; Diabetes Mellitus, Type 1; Fibroblasts; Foreskin; Glucagon; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Pluripotent Stem Cells; Somatostatin; Transcriptional Activation | 2010 |
Glucagon-like peptide-2, but not glucose-dependent insulinotropic polypeptide, stimulates glucagon release in patients with type 1 diabetes.
Topics: Adult; Diabetes Mellitus, Type 1; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 2; Humans; Time Factors; Young Adult | 2010 |
Protective effect of beta-casomorphin-7 on type 1 diabetes rats induced with streptozotocin.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Type 1; Endorphins; Glucagon; Glycogen; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Malondialdehyde; Oxidative Stress; Oxidoreductases; Peptide Fragments; Random Allocation; Rats; Rats, Sprague-Dawley; Streptozocin; Time Factors; Weight Gain | 2010 |
[GADA persistence and detectable C peptide in patients with long standing diabetes mellitus type 1].
Topics: Adult; Autoantibodies; Autoimmune Diseases; Biomarkers; C-Peptide; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Female; Glucagon; Glutamate Decarboxylase; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Male | 2010 |
Glucagon supports postabsorptive plasma glucose concentrations in humans with biologically optimal insulin levels.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Infusions, Intravenous; Insulin; Intestinal Absorption; Male; Reference Values | 2010 |
Glucose homeostasis in pre-diabetic NOD and lymphocyte-deficient NOD/SCID mice during gestation.
Topics: Animals; Blood Glucose; Corticosterone; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Homeostasis; Insulin; Insulin Resistance; Islets of Langerhans; Lymphocytes; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, SCID; Pancreas; Prediabetic State; Pregnancy; Pregnancy in Diabetics | 2010 |
Paracrinology of islets and the paracrinopathy of diabetes.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Glucagon-Secreting Cells; Humans; Insulin-Secreting Cells; Paracrine Communication | 2010 |
Insulin reciprocally regulates glucagon secretion in humans.
Topics: Adolescent; Adult; Age of Onset; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Clamp Technique; Glycated Hemoglobin; Homeostasis; Humans; Insulin; Male; Young Adult | 2010 |
Role of GLP-1 induced glucagon suppression in type 2 diabetes mellitus.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Humans; Insulin; Male | 2010 |
Continuous glucose monitoring in subjects with type 1 diabetes: improvement in accuracy by correcting for background current.
Topics: Adult; Algorithms; Artificial Intelligence; Biosensing Techniques; Blood Glucose; Blood Glucose Self-Monitoring; Calibration; Data Interpretation, Statistical; Diabetes Mellitus, Type 1; Female; Glucagon; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemia; Insulin Infusion Systems; Male; Middle Aged; Monitoring, Physiologic; Reference Standards; Reproducibility of Results | 2010 |
Glucose-responsive beta cells in islets isolated from a patient with long-standing type 1 diabetes mellitus.
Topics: Adult; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Humans; In Vitro Techniques; Insulin; Insulin-Secreting Cells; Young Adult | 2011 |
Insulin-induced hypoglycemia increases hepatic sensitivity to glucagon in dogs.
Topics: 3-Hydroxybutyric Acid; AMP-Activated Protein Kinases; Animals; Diabetes Mellitus, Type 1; Disease Models, Animal; Dogs; Enzyme Activation; Fatty Acids, Nonesterified; Female; Glucagon; Gluconeogenesis; Glycogenolysis; Humans; Hypoglycemia; Insulin; Liver; Liver Glycogen; Male; Signal Transduction | 2010 |
β-cell function and metabolic control in latent autoimmune diabetes in adults with early insulin versus conventional treatment: a 3-year follow-up.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; C-Peptide; Diabetes Mellitus, Type 1; Female; Follow-Up Studies; Glucagon; Glycated Hemoglobin; Humans; Insulin; Insulin-Secreting Cells; Male; Middle Aged; Regression Analysis; Sweden; Treatment Outcome | 2011 |
[Conversion of adult pancreatic alpha-cells to beta-cells in diabetic mice].
Topics: Animals; Autoimmune Diseases; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucagon; Glucagon-Secreting Cells; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mice; Phenotype; Regeneration | 2010 |
Factors influencing the effectiveness of glucagon for preventing hypoglycemia.
Topics: Adult; Algorithms; Automation; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Infusions, Subcutaneous; Insulin; Insulin Infusion Systems; Monitoring, Physiologic; Pancreas, Artificial; Time Factors | 2010 |
Xenograft of microencapsulated sertoli cells reverses T1DM in NOD mice by inducing neogenesis of beta-cells.
Topics: Animals; Autoantibodies; Basic Helix-Loop-Helix Transcription Factors; Blood Glucose; Diabetes Mellitus, Type 1; Eye Proteins; Glucagon; Homeodomain Proteins; Immunohistochemistry; Insulin; Insulin Antibodies; Insulin-Secreting Cells; Male; Mice; Mice, Inbred NOD; Nerve Tissue Proteins; Paired Box Transcription Factors; Pancreatitis-Associated Proteins; PAX6 Transcription Factor; Polymerase Chain Reaction; Proteins; Proto-Oncogene Proteins c-kit; Repressor Proteins; Sertoli Cells; Somatostatin; Testis; Trans-Activators; Transplantation, Heterologous | 2010 |
Proinsulin/C-peptide ratio, glucagon and remission in new-onset Type 1 diabetes mellitus in young adults.
Topics: Adolescent; Adult; Biomarkers; C-Peptide; Diabetes Mellitus, Type 1; Disease Progression; Fasting; Female; Glucagon; Glycated Hemoglobin; Humans; Insulin Resistance; Male; Proinsulin; Prospective Studies; Reference Values; Remission Induction; Young Adult | 2011 |
Nesfatin-1 exerts a direct, glucose-dependent insulinotropic action on mouse islet β- and MIN6 cells.
Topics: Animals; Calcium-Binding Proteins; Cell Line; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Glucagon; Glucose; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Nucleobindins; Obesity | 2011 |
Glucagon as a critical factor in the pathology of diabetes.
Topics: Animals; Diabetes Mellitus, Type 1; Glucagon; Mice; Mice, Knockout; Receptors, Glucagon | 2011 |
Glucagon receptor knockout prevents insulin-deficient type 1 diabetes in mice.
Topics: Animals; Blood Glucose; Blotting, Western; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Enzyme-Linked Immunosorbent Assay; Fatty Acids; Glucagon; Hyperglycemia; Immunohistochemistry; Insulin; Insulin-Like Growth Factor I; Liver; Mice; Mice, Knockout; Pancreas; Radioimmunoassay; Receptors, Glucagon; Reverse Transcriptase Polymerase Chain Reaction | 2011 |
Pancreatic volume and endocrine and exocrine functions in patients with diabetes.
Topics: Adult; Aged; Atrophy; C-Peptide; Chymotrypsin; Cohort Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Feces; Female; Glucagon; Humans; Islets of Langerhans; Male; Middle Aged; Organ Size; Pancreas; Pancreas, Exocrine; Pancreatic Elastase; Tomography, X-Ray Computed | 2011 |
The ALBA project: an evaluation of needs, management, fears of Italian young patients with type 1 diabetes in a school setting and an evaluation of parents' and teachers' perceptions.
Topics: Adolescent; Attitude to Health; Child; Diabetes Mellitus, Type 1; Disease Management; Faculty; Fear; Glucagon; Health Services Needs and Demand; Humans; Hyperglycemia; Hypoglycemia; Insulin; Italy; Parents; Schools; Surveys and Questionnaires | 2011 |
The effect of glycemic variability on counterregulatory hormone responses to hypoglycemia in young children and adolescents with type 1 diabetes.
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucagon; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Male | 2011 |
Therapeutic impact of leptin on diabetes, diabetic complications, and longevity in insulin-deficient diabetic mice.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Eating; Glucagon; Hyperglycemia; Insulin; Leptin; Longevity; Mice; Mice, Transgenic; Oxidative Stress; Pancreas | 2011 |
The message for MODY.
Topics: Autoantibodies; C-Peptide; Creatinine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Genetic Predisposition to Disease; Glucagon; Glutamate Decarboxylase; Glycated Hemoglobin; Humans; Immunologic Factors; Male; Mutation; RNA, Messenger; Transcription, Genetic | 2011 |
Urine C-peptide creatinine ratio is an alternative to stimulated serum C-peptide measurement in late-onset, insulin-treated diabetes.
Topics: Age of Onset; Aged; C-Peptide; Creatinine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Male; Middle Aged; Sensitivity and Specificity | 2011 |
High-resolution magnetic resonance imaging quantitatively detects individual pancreatic islets.
Topics: Algorithms; Animals; Chlorides; Contrast Media; Diabetes Mellitus, Type 1; Glucagon; Glucagon-Secreting Cells; Glucose; Image Enhancement; Immunohistochemistry; Infusions, Intravenous; Injections, Intraperitoneal; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Magnetic Resonance Imaging; Manganese Compounds; Mice; Mice, Inbred C57BL; Organ Size; Streptozocin | 2011 |
Proinsulin, GLP-1, and glucagon are associated with partial remission in children and adolescents with newly diagnosed type 1 diabetes.
Topics: Adolescent; Age of Onset; Blood Glucose; C-Peptide; Child; Child, Preschool; Cohort Studies; Diabetes Mellitus, Type 1; Female; Follow-Up Studies; Glucagon; Glucagon-Like Peptide 1; Humans; Infant; Infant, Newborn; Male; Proinsulin; Remission, Spontaneous | 2012 |
Characterization of a novel functional protein in the pancreatic islet: islet homeostasis protein regulation of glucagon synthesis in α cells.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Diabetes Mellitus, Type 1; Female; Gene Expression; Glucagon; Glucagon-Secreting Cells; Glucose; Humans; Immunohistochemistry; In Situ Hybridization; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Mice; Mice, Inbred NOD; Proteins; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference | 2012 |
Glucagon injection for type 1 diabetes in children.
Topics: Child; Diabetes Mellitus, Type 1; Drug Utilization; Emergencies; Gastrointestinal Agents; Glucagon; Health Knowledge, Attitudes, Practice; Health Policy; Humans; Injections; Nursing Audit; Practice Patterns, Nurses'; United Kingdom | 2011 |
Closed-loop insulin delivery: we're "virtually" there.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Male | 2012 |
Concordance of changes in metabolic pathways based on plasma metabolomics and skeletal muscle transcriptomics in type 1 diabetes.
Topics: 3-Hydroxybutyric Acid; Adult; Amino Acids; Bicarbonates; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 1; Female; Gene Expression Profiling; Gene Expression Regulation; Glucagon; Glycated Hemoglobin; Humans; Insulin; Lipids; Male; Metabolomics; Muscle, Skeletal; Protein Array Analysis; Signal Transduction; Transcriptome | 2012 |
Novel pancreatic beta cell-specific proteins: antibody-based proteomics for identification of new biomarker candidates.
Topics: Antibodies; Biomarkers; Databases, Protein; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Guanine Nucleotide Exchange Factors; Humans; Immunohistochemistry; Insulin; Insulin-Secreting Cells; Membrane Glycoproteins; Microscopy, Confocal; Platelet Glycoprotein GPIb-IX Complex; Proteomics; Receptors, Immunologic; Receptors, Prostaglandin; Serpins | 2012 |
Does glucagon stimulation test help to predict autoimmunity in newly diagnosed non obese adults with diabetes?
Topics: Adult; Autoantibodies; Body Mass Index; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Glutamate Decarboxylase; Humans; Male; Middle Aged | 2012 |
Early loss of the glucagon response to hypoglycemia in adolescents with type 1 diabetes.
Topics: Adolescent; Arginine; Child; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Male | 2012 |
Enhanced function of pancreatic islets co-encapsulated with ECM proteins and mesenchymal stromal cells in a silk hydrogel.
Topics: Animals; Cell Differentiation; Cell Separation; Cell Survival; Collagen Type IV; Diabetes Mellitus, Type 1; Extracellular Matrix Proteins; Female; Glucagon; Glucose; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Laminin; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Silk; Somatostatin; Tissue Scaffolds | 2012 |
Hypoglycemia-induced increases in thalamic cerebral blood flow are blunted in subjects with type 1 diabetes and hypoglycemia unawareness.
Topics: Adolescent; Adult; Aged; Awareness; Blood Glucose; Cerebrovascular Circulation; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Hormones; Humans; Hypoglycemia; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Thalamus; Young Adult | 2012 |
Blood glucose control in type 1 diabetes with a bihormonal bionic endocrine pancreas.
Topics: Adolescent; Adult; Aged; Blood Glucose; Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemia; Insulin; Islets of Langerhans; Male; Middle Aged; Young Adult | 2012 |
β- and α-cell dysfunctions in africans with ketosis-prone atypical diabetes during near-normoglycemic remission.
Topics: Adult; Black People; C-Peptide; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Female; Glucagon; Glucagon-Secreting Cells; Glucose Tolerance Test; Humans; Insulin; Insulin-Secreting Cells; Male; Middle Aged | 2013 |
In situ electrophysiological examination of pancreatic α cells in the streptozotocin-induced diabetes model, revealing the cellular basis of glucagon hypersecretion.
Topics: Action Potentials; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Electrophysiological Phenomena; Exocytosis; Glucagon; Glucagon-Secreting Cells; Glucose Intolerance; Hyperglycemia; Mice; Potassium Channels, Voltage-Gated; Secretory Vesicles; Voltage-Gated Sodium Channels | 2013 |
Hormonal response during physical exercise of different intensities in adolescents with type 1 diabetes and healthy controls.
Topics: Adolescent; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exercise Test; Female; Glucagon; Glycated Hemoglobin; Hormones; Human Growth Hormone; Humans; Hydrocortisone; Insulin; Lactic Acid; Male; Norepinephrine; Oxygen Consumption; Puberty; Sex Factors; Young Adult | 2012 |
BDNF action in the brain attenuates diabetic hyperglycemia via insulin-independent inhibition of hepatic glucose production.
Topics: Animals; Behavior, Animal; Biological Transport; Brain-Derived Neurotrophic Factor; Diabetes Mellitus, Type 1; Feeding Behavior; Glucagon; Gluconeogenesis; Glucose; Hyperglycemia; Hypoglycemic Agents; Injections, Intraventricular; Insulin; Lateral Ventricles; Liver; Male; Neurons; Rats; Rats, Wistar; Ventromedial Hypothalamic Nucleus | 2013 |
Lack of association between residual insulin production and glucagon response to hypoglycemia in youth with short duration of type 1 diabetes.
Topics: Adolescent; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemia; Insulin; Male; Young Adult | 2013 |
Long-term reversal of diabetes in non-obese diabetic mice by liver-directed gene therapy.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Basic Helix-Loop-Helix Transcription Factors; Blood Glucose; Cell Transdifferentiation; Diabetes Mellitus, Type 1; Female; Furin; Genetic Therapy; Genetic Vectors; Glucagon; Glucose Tolerance Test; Hepatocytes; Homeobox Protein Nkx-2.2; Homeodomain Proteins; Insulin; Insulin-Secreting Cells; Lentivirus; Liver; Mice; Mice, Inbred NOD; Nerve Tissue Proteins; Oligonucleotide Array Sequence Analysis; Paired Box Transcription Factors; Somatostatin; Trans-Activators; Transcription Factors; Transduction, Genetic; Zebrafish Proteins | 2013 |
Fasting and postprandial liver glycogen content in patients with type 1 diabetes mellitus after successful pancreas-kidney transplantation with systemic venous insulin delivery.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Fasting; Female; Glucagon; Humans; Insulin; Kidney Transplantation; Liver Glycogen; Male; Middle Aged; Pancreas Transplantation; Postprandial Period; Radioimmunoassay | 2014 |
The future of care for type 1 diabetes.
Topics: Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin Aspart; Male; Pancreas, Artificial | 2013 |
The effect of walking before and after breakfast on blood glucose levels in patients with type 1 diabetes treated with intensive insulin therapy.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 1; Eating; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Humans; Hypoglycemic Agents; Insulin; Kinetics; Male; Middle Aged; Norepinephrine; Postprandial Period; Walking | 2002 |
P.E.D.S.: a curriculum for diabetes care in the schools. Pediatric Education for Diabetics in Schools.
Topics: Adult; Blood Glucose; Child; Curriculum; Diabetes Mellitus, Type 1; Dietetics; Education, Nursing, Continuing; Faculty; Glucagon; Health Knowledge, Attitudes, Practice; Humans; Insulin; Parents; Schools | 2002 |
Anti-diabetogenic effect of the human amylin analogue, pramlintide, in Type 1 diabetes is not mediated by GLP-1.
Topics: Adult; Amyloid; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Hypoglycemic Agents; Islet Amyloid Polypeptide; Male; Peptide Fragments; Protein Precursors | 2002 |
Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice.
Topics: Animals; Apoptosis; Blood Glucose; Cell Division; Diabetes Mellitus; Diabetes Mellitus, Type 1; Exenatide; Female; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Hyperglycemia; Insulin; Islets of Langerhans; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Peptide Fragments; Peptides; Protein Precursors; Venoms | 2002 |
A case of fulminant type 1 diabetes with graves' disease.
Topics: Adult; Amylases; Autoantibodies; Biomarkers; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Graves Disease; Humans; Ketone Bodies; Lipase; Pregnancy; Pregnancy in Diabetics | 2002 |
Reduction of hepatic glycogen synthesis and breakdown in patients with agenesis of the dorsal pancreas.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Gluconeogenesis; Glucose Tolerance Test; Glycogen; Human Growth Hormone; Humans; Hydrocortisone; Insulin; Insulin Resistance; Insulin Secretion; Kinetics; Leptin; Liver; Magnetic Resonance Spectroscopy; Male; Middle Aged; Norepinephrine; Pancreas | 2002 |
Residual insulin secretion is not coupled to a maintained glucagon response to hypoglycaemia in long-term type 1 diabetes.
Topics: Adult; Autonomic Nervous System; Blood Glucose; C-Peptide; Data Interpretation, Statistical; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Infusions, Intravenous; Injections, Subcutaneous; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Pancreatic Polypeptide; Radioimmunoassay; Time Factors | 2002 |
AICAR and phlorizin reverse the hypoglycemia-specific defect in glucagon secretion in the diabetic BB rat.
Topics: Aminoimidazole Carboxamide; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Hypoglycemia; Hypoglycemic Agents; Insulin; Norepinephrine; Phlorhizin; Rats; Rats, Inbred BB; Ribonucleotides | 2002 |
The role of autoimmunity in islet allograft destruction: major histocompatibility complex class II matching is necessary for autoimmune destruction of allogeneic islet transplants after T-cell costimulatory blockade.
Topics: Animals; Autoimmune Diseases; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Glucagon; Graft Survival; Histocompatibility Antigens Class II; Histocompatibility Testing; Insulin; Islets of Langerhans Transplantation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Inbred Strains; Species Specificity; T-Lymphocytes; Time Factors; Transplantation, Homologous | 2002 |
Effect of gender on counterregulatory responses to euglycemic exercise in type 1 diabetes.
Topics: Adult; Blood Glucose; Calorimetry, Indirect; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glycerol; Homeostasis; Human Growth Hormone; Humans; Hydrocortisone; Insulin; Kinetics; Lactic Acid; Lipolysis; Male; Norepinephrine; Oxygen Consumption; Pancreatic Polypeptide; Physical Fitness; Pulmonary Gas Exchange; Sex Characteristics | 2002 |
Reduction of plasma leptin concentrations by arginine but not lipid infusion in humans.
Topics: Adult; Arginine; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Glucagon; Glycerol; Heparin; Humans; Insulin; Kinetics; Leptin; Male; Middle Aged; Somatostatin | 2002 |
Growth inhibitors promote differentiation of insulin-producing tissue from embryonic stem cells.
Topics: Androstadienes; Animals; Biomarkers; Cell Aggregation; Cell Differentiation; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Embryo, Mammalian; Enzyme Inhibitors; Glucagon; Growth Inhibitors; Homeostasis; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasms, Experimental; Niacinamide; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Stem Cell Transplantation; Stem Cells; Streptozocin; Weight Loss; Wortmannin | 2002 |
Intrahepatic islet transplantation in type 1 diabetic patients does not restore hypoglycemic hormonal counterregulation or symptom recognition after insulin independence.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Hormones; Humans; Hypoglycemia; Insulin; Islets of Langerhans Transplantation; Liver; Male; Middle Aged | 2002 |
[Pancreatic stem cells--a new therapeutic option for the treatment of type 1 diabetes mellitus?].
Topics: Adult; alpha-Fetoproteins; Amylases; Cell Differentiation; Cells, Cultured; Diabetes Mellitus, Type 1; Embryo, Mammalian; Fluorescence; Glucagon; Humans; Immunohistochemistry; Insulin; Insulin Secretion; Intermediate Filament Proteins; Islets of Langerhans; Keratins; Multipotent Stem Cells; Nerve Tissue Proteins; Nestin; Pancreas; Phenotype; Stem Cells; Transcription Factors | 2002 |
A mathematical model for pattern of change in beta-cell reserve and factors affecting residual reserve within the first 2 years of type 1 diabetes.
Topics: Adolescent; Adult; Aging; Autoantibodies; C-Peptide; Diabetes Mellitus, Type 1; Fasting; Female; Glucagon; Humans; Islets of Langerhans; Male; Mathematics; Models, Biological; Time Factors | 2002 |
Glucagon-like peptide 1 content of intestinal tract in adult rats injected with streptozotocin either during neonatal period or 7 d before sacrifice.
Topics: Animals; Animals, Newborn; Blood Glucose; Body Weight; Cecum; Colon; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Glucagon-Like Peptide 1; Ileum; Insulin; Intestines; Jejunum; Male; Pancreas; Peptide Fragments; Protein Precursors; Proteins; Rats; Rats, Inbred BB; Rats, Wistar; Streptozocin | 2002 |
Characterization of antibody responses to endogenous and exogenous antigen in the nonobese diabetic mouse.
Topics: Adjuvants, Immunologic; Aluminum Hydroxide; Animals; Antibody Specificity; Autoantibodies; Autoantigens; Autoimmune Diseases; Cattle; Diabetes Mellitus, Type 1; Diphtheria-Tetanus-Pertussis Vaccine; Female; Glucagon; Glutamate Decarboxylase; Humans; Immunization; Immunoglobulin G; Insulin; Isoenzymes; Mannitol; Membrane Proteins; Methyltransferases; Mice; Mice, Inbred NOD; Oleic Acids; Phosphatidylethanolamine N-Methyltransferase; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Receptor-Like Protein Tyrosine Phosphatases, Class 8; Recombinant Fusion Proteins; Risk; Species Specificity; Swine; Th2 Cells | 2003 |
Functional and immunohistochemical evaluation of porcine neonatal islet-like cell clusters.
Topics: Animals; Animals, Newborn; Arginine; Cell Culture Techniques; Cell Differentiation; Cell Division; Cells, Cultured; Diabetes Mellitus, Type 1; Glucagon; Glucose; Glucose Tolerance Test; Graft Survival; Immunohistochemistry; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Keratin-7; Keratins; Ki-67 Antigen; Male; Mice; Mice, Nude; Somatostatin; Sus scrofa; Transplantation, Heterologous | 2003 |
Heterotopic pancreas without exocrine elements in the Meckel's diverticulum of an insulin-dependant diabetic.
Topics: Adolescent; Choristoma; Diabetes Mellitus, Type 1; Glucagon; Humans; Ileal Diseases; Immunohistochemistry; Male; Meckel Diverticulum; Pancreas; Somatostatin; Treatment Outcome | 2003 |
Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus.
Topics: Adult; Aged; Blood Glucose; Body Weight; C-Peptide; Case-Control Studies; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Feeding Behavior; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Obesity; Peptide Fragments; Protein Precursors; Random Allocation | 2003 |
Effect of antecedent hypoglycemia on counterregulatory responses to subsequent euglycemic exercise in type 1 diabetes.
Topics: Adult; Amino Acids; Blood Glucose; Blood Pressure; Body Mass Index; Calorimetry, Indirect; Diabetes Mellitus, Type 1; Exercise; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Clamp Technique; Glycated Hemoglobin; Heart Rate; Homeostasis; Human Growth Hormone; Humans; Hypoglycemia; Insulin; Male | 2003 |
Optimizing insulin regimens in type 1 diabetes. How to help patients get control of their life.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemic Agents; Insulin; Insulin Glargine; Insulin, Long-Acting | 2003 |
Impaired glucagon response to sympathetic nerve stimulation in the BB diabetic rat: effect of early sympathetic islet neuropathy.
Topics: Animals; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Electric Stimulation; Epinephrine; Female; Glucagon; Islets of Langerhans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Neuropeptides; Neurotransmitter Agents; Oxidopamine; Portal Vein; Rats; Rats, Inbred BB; Rats, Wistar; Sympathectomy, Chemical; Sympathetic Nervous System; Vesicular Biogenic Amine Transport Proteins | 2003 |
Interferon-alpha reduces insulin resistance and beta-cell secretion in responders among patients with chronic hepatitis B and C.
Topics: Adult; Alanine Transaminase; Analysis of Variance; Autoantibodies; Blood Glucose; C-Peptide; Chi-Square Distribution; Diabetes Mellitus, Type 1; DNA, Viral; Female; Glucagon; Glucose Tolerance Test; Hepatitis B e Antigens; Hepatitis B, Chronic; Hepatitis C, Chronic; Homeostasis; Humans; Insulin; Insulin Resistance; Insulin Secretion; Interferon-alpha; Islets of Langerhans; Male; Middle Aged | 2003 |
Clinical use of glucagon in juvenile diabetes mellitus.
Topics: Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; Humans; Infant | 1960 |
HYPOGLYCEMIA IN JUVENILE DIABETES.
Topics: Adolescent; Carbohydrates; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin, Long-Acting; Minnesota; Protamines; Toxicology | 1963 |
VARIATIONS IN GLUCAGON RESPONSE AMONG JUVENILE DIABETICS.
Topics: Adolescent; Child; Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Placebos | 1963 |
[EFFECT OF GLUCAGON ON BLOOD GLUCOSE AND PLASMA NON-ESTERIFIED FATTY ACIDS CONCENTRATIONS].
Topics: Adolescent; Blood; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus; Diabetes Mellitus, Type 1; Fatty Acids; Fatty Acids, Nonesterified; Glucagon; Humans; Hyperglycemia; Lactates; Lipid Metabolism; Liver Diseases | 1964 |
ALCOHOL HYPOGLYCEMIA. EFFECTS OF ETHANOL ON PLASMA. 3. GLUCOSE, KETONES, AND FREE FATTY ACIDS IN "JUVENILE" DIABETICS: A MODEL FOR "NONKETOTIC DIABETIC ACIDOSIS"?
Topics: Acidosis; Adolescent; Biomedical Research; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Ethanol; Fatty Acids; Fatty Acids, Nonesterified; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Ketone Bodies; Ketones | 1964 |
LIPOATROPHIC DIABETES. I. STUDIES CONCERNING ENDOCRINE FUNCTION AND CARBOHYDRATE METABOLISM.
Topics: Adolescent; Carbohydrate Metabolism; Diabetes Mellitus, Lipoatrophic; Diabetes Mellitus, Type 1; Drug Tolerance; Epinephrine; Fatty Acids; Glucagon; Glucose Tolerance Test; Hepatomegaly; Humans; Infant; Insulin; Insulin Resistance; L-Lactate Dehydrogenase; Leucine; Lipids; Lipodystrophy; Liver; Liver Cirrhosis; Liver Function Tests; Metyrapone; Pharmacology; Pituitary-Adrenal Function Tests; Radiography; Tolbutamide; Transaminases; Urine | 1965 |
Counterregulatory hormone and symptom responses to insulin-induced hypoglycemia in the postprandial state in humans.
Topics: Adult; Area Under Curve; Body Mass Index; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Glucose; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Infusions, Intravenous; Insulin; Kinetics; Norepinephrine; Pancreatic Polypeptide; Postprandial Period; Posture; Reference Values | 2003 |
Can amylin analogue lead to better diabetes control?
Topics: Amyloid; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Management; Glucagon; Humans; Hypoglycemic Agents; Insulin; Managed Care Programs; United States; Weight Gain | 2003 |
Bioactive GLP-1 in gut, receptor expression in pancreas, and insulin response to GLP-1 in diabetes-prone rats.
Topics: Animals; Blood Glucose; Blotting, Northern; Diabetes Mellitus, Type 1; Female; Gastrointestinal Tract; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Immunohistochemistry; Insulin; Male; Pancreas; Peptide Fragments; Protein Precursors; Rats; Rats, Inbred BB; Receptors, Glucagon | 2004 |
Upper gastrointestinal responses to intraduodenal nutrient in type 1 diabetes mellitus.
Topics: Adult; Autonomic Nervous System; Blood Glucose; Diabetes Mellitus, Type 1; Duodenum; Eating; Female; Gastric Emptying; Gastric Inhibitory Polypeptide; Gastrointestinal Motility; Glucagon; Glucagon-Like Peptide 1; Humans; Hunger; Male; Manometry; Middle Aged; Parenteral Nutrition; Peptide Fragments; Pressure; Protein Precursors; Pyloric Antrum | 2004 |
Increasing incidence of diabetes after gestational diabetes: a long-term follow-up in a Danish population.
Topics: Adult; Body Mass Index; Cohort Studies; Denmark; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Follow-Up Studies; Gestational Age; Glucagon; Glucose Tolerance Test; Humans; Incidence; Infant, Newborn; Middle Aged; Pregnancy; Time Factors | 2004 |
Differentiation of human embryonic stem cells into insulin-producing clusters.
Topics: Apoptosis; Cell Culture Techniques; Cell Differentiation; Cells, Cultured; Diabetes Mellitus, Type 1; Embryo, Mammalian; Glucagon; Humans; Immunohistochemistry; In Situ Hybridization; Insulin; Insulin Secretion; Islets of Langerhans; Niacinamide; Somatostatin; Stem Cells | 2004 |
Transient chylomicronemia preceding the onset of insulin-dependent diabetes in a young girl with no humoral markers of islet autoimmunity.
Topics: Autoantibodies; Autoimmunity; C-Peptide; Child; Chylomicrons; Diabetes Mellitus, Type 1; Fasting; Female; Glucagon; Glucose Clamp Technique; Humans; Hypercholesterolemia; Hyperglycemia; Hypertriglyceridemia; Islets of Langerhans; Lipoprotein Lipase | 2004 |
Mini-dose glucagon is effective at diabetes camp.
Topics: Child; Diabetes Mellitus, Type 1; Gastrointestinal Agents; Glucagon; Humans; Hypoglycemia | 2004 |
Regulation of net hepatic glycogenolysis and gluconeogenesis during exercise: impact of type 1 diabetes.
Topics: Adult; Blood Glucose; Calorimetry, Indirect; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Female; Glucagon; Gluconeogenesis; Glucose; Humans; Hydrocortisone; Insulin; Liver Glycogen; Male; Oxygen Consumption | 2004 |
[Risk for patients often underestimated].
Topics: Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; First Aid; Glucagon; Glycated Hemoglobin; Humans; Hypoglycemia; Insulin; Patient Education as Topic; Risk | 2004 |
[Diabetic coma and hypoglycemia in children. What to do when in an emergency].
Topics: Age Factors; Child; Diabetes Mellitus, Type 1; Diabetic Coma; Emergencies; Glucagon; Humans; Hypoglycemia; Infant, Newborn; Injections, Intramuscular; Injections, Intravenous; Insulin; Male | 2004 |
Immunohistochemical demonstration of leptin in pancreatic islets of non-obese diabetic and CD-1 mice: co-localization in glucagon cells and its attenuation at the onset of diabetes.
Topics: Animals; Cattle; Diabetes Mellitus, Type 1; Female; Gene Expression Regulation; Glucagon; Guinea Pigs; Insulin; Islets of Langerhans; Leptin; Male; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Sheep; Species Specificity; Swine | 2004 |
Hypoplasia of endocrine and exocrine pancreas in homozygous transgenic TGF-beta1.
Topics: Animals; Cell Cycle; Cell Cycle Proteins; Crosses, Genetic; Cyclin-Dependent Kinase Inhibitor p15; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Homozygote; Hyperglycemia; Insulin; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Transgenic; Pancreas, Exocrine; Promoter Regions, Genetic; Swine; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Suppressor Proteins | 2005 |
Pubertal stage and hypoglycaemia counterregulation in type 1 diabetes.
Topics: Adolescent; Analysis of Variance; Autonomic Nervous System; Blood Glucose; Child; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Norepinephrine; Pancreatic Polypeptide; Puberty; Sweating | 2005 |
Caspase-3-dependent beta-cell apoptosis in the initiation of autoimmune diabetes mellitus.
Topics: Animals; Apoptosis; Caspase 3; Caspases; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucagon; Insulin; Islets of Langerhans; Lymphocyte Activation; Mice; Mice, Knockout; Pancrelipase; T-Lymphocytes | 2005 |
The favorable outcome of human islet transplantation in Korea: experiences of 10 autologous transplantations.
Topics: Administration, Oral; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Islets of Langerhans Transplantation; Korea; Pancreatectomy; Transplantation, Autologous; Treatment Outcome | 2005 |
The role of intramyocellular lipids during hypoglycemia in patients with intensively treated type 1 diabetes.
Topics: Adipose Tissue; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Glucose; Glycerol; Humans; Hydrocortisone; Hypoglycemia; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Kinetics; Lipid Metabolism; Lipolysis; Male; Microdialysis; Muscle Cells; Muscle, Skeletal | 2005 |
Symlin for adults with type 1 and type 2 diabetes.
Topics: Adult; Amyloid; Appetite; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Drug Administration Schedule; Gastric Emptying; Glucagon; Humans; Hypoglycemic Agents; Islet Amyloid Polypeptide; Metabolic Clearance Rate; Nurse Practitioners; Nurse's Role; Patient Education as Topic; Patient Selection | 2005 |
Preservation of beta-cell function during immune-mediated, B7-1-dependent alpha-cell destruction.
Topics: Animals; B7-1 Antigen; Cell Death; Crosses, Genetic; Diabetes Mellitus, Type 1; Glucagon; Glucagon-Like Peptide 1; Immunohistochemistry; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Peptide Fragments; Protein Precursors; Reverse Transcriptase Polymerase Chain Reaction; Statistics, Nonparametric; Tumor Necrosis Factor-alpha | 2005 |
Reduced intrahepatic fat content is associated with increased whole-body lipid oxidation in patients with type 1 diabetes.
Topics: Adiponectin; Adult; Anthropometry; Blood Glucose; Calorimetry, Indirect; Case-Control Studies; Diabetes Mellitus, Type 1; Energy Metabolism; Female; Glucagon; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Lipid Metabolism; Lipids; Liver; Magnetic Resonance Spectroscopy; Male; Oxidation-Reduction | 2005 |
p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis.
Topics: Acetylcysteine; Adenoviridae; Animals; Cell Line, Tumor; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Type 1; Disease Models, Animal; Enzyme Inhibitors; Gene Silencing; Glucagon; Gluconeogenesis; Glucose; Glucose-6-Phosphatase; Hepatocytes; Imidazoles; Liver; Mice; p38 Mitogen-Activated Protein Kinases; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphoenolpyruvate Carboxykinase (GTP); Phosphorylation; Promoter Regions, Genetic; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Streptozocin; Trans-Activators; Transcription Factors; Transfection | 2005 |
Is early and late post-meal exercise so different in type 1 diabetic lispro users?
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Exercise; Female; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Lispro; Male; Postprandial Period; Time Factors | 2006 |
Human fetal islet transplantation in type 1 diabetics: comparison of immunological effects between multiple implantation regimens.
Topics: CD4-CD8 Ratio; Cell Culture Techniques; Diabetes Mellitus, Type 1; Fetal Tissue Transplantation; Gestational Age; Glucagon; Graft Rejection; Humans; Injections, Intramuscular; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Lymphocyte Subsets | 2005 |
Inflammatory cytokine, growth factor and counterregulatory responses to exercise in children with type 1 diabetes and healthy controls.
Topics: Adaptation, Physiological; Adolescent; Blood Glucose; Case-Control Studies; Child; Diabetes Mellitus, Type 1; Exercise; Female; Glucagon; Human Growth Hormone; Humans; Insulin-Like Growth Factor I; Interleukin-6; Male; Norepinephrine; Oxygen Consumption | 2006 |
Cerebral glutamate metabolism during hypoglycaemia in healthy and type 1 diabetic humans.
Topics: Adult; Blood Glucose; Creatine; Diabetes Mellitus, Type 1; Energy Metabolism; Epinephrine; Glucagon; Glucose; Glucose Clamp Technique; Glutamic Acid; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Magnetic Resonance Spectroscopy; Male; Occipital Lobe | 2006 |
Mini-dose glucagon rescue for mild hypoglycaemia in children with type 1 diabetes: the Brisbane experience.
Topics: Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Glucagon; Hormones; Humans; Hypoglycemia; Infant; Injections; Outpatient Clinics, Hospital; Queensland; Self Administration; Syringes | 2006 |
Corticotrophin-releasing factor receptors within the ventromedial hypothalamus regulate hypoglycemia-induced hormonal counterregulation.
Topics: Animals; Corticosterone; Corticotropin-Releasing Hormone; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Humans; Hypoglycemia; In Vitro Techniques; Male; Microinjections; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Urocortins; Ventromedial Hypothalamic Nucleus | 2006 |
NR4A orphan nuclear receptors are transcriptional regulators of hepatic glucose metabolism.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Glucagon; Gluconeogenesis; Glucose; Humans; Hyperglycemia; Liver; Male; Mice; Nuclear Receptor Subfamily 4, Group A, Member 1; Nuclear Receptor Subfamily 4, Group A, Member 2; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Transcription Factors | 2006 |
Insulin therapy during diabetic ketoacidosis in children.
Topics: Adolescent; Bicarbonates; Child; Child, Preschool; Combined Modality Therapy; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Electrolytes; Emergencies; Female; Fluid Therapy; Glucagon; Human Growth Hormone; Humans; Hydrocortisone; Infant; Insulin; Ketone Bodies; Male; Malonyl Coenzyme A; Mitochondria, Liver; Practice Guidelines as Topic; Recurrence | 2005 |
Oxyntomodulin increases intrinsic heart rate in mice independent of the glucagon-like peptide-1 receptor.
Topics: Animals; Autonomic Nervous System; Blood Pressure; Body Temperature; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; Eating; Electrocardiography; Epinephrine; Exenatide; Female; Glucagon; Glucagon-Like Peptide-1 Receptor; Heart; Heart Rate; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Norepinephrine; Oxyntomodulin; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Glucagon; Telemetry; Venoms | 2007 |
Metabolic factors affecting residual beta cell function assessed by C-peptide secretion in patients with newly diagnosed type 1 diabetes.
Topics: Adolescent; Adult; Biomarkers; Body Mass Index; C-Peptide; Child; Child, Preschool; Diabetes Mellitus, Type 1; Early Diagnosis; Female; Glucagon; Glycated Hemoglobin; Hormones; Humans; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Male; Multivariate Analysis; Prognosis; Radioimmunoassay | 2006 |
Young NOD mice show increased diabetes sensitivity to low doses of streptozotocin.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Female; Glucagon; Histocytochemistry; Immunohistochemistry; Incidence; Insulin; Islets of Langerhans; Mice; Mice, Inbred NOD; Mice, Inbred Strains; Streptozocin; Time Factors | 2006 |
Effect of the amino acid alanine on glucagon secretion in non-diabetic and type 1 diabetic subjects during hyperinsulinaemic euglycaemia, hypoglycaemia and post-hypoglycaemic hyperglycaemia.
Topics: Adolescent; Adult; Alanine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Homeostasis; Humans; Hyperglycemia; Hypoglycemia; Male; Middle Aged; Norepinephrine; Reference Values | 2007 |
Islet transplantation.
Topics: Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Insulin; Insulin Secretion; Islets of Langerhans Transplantation | 2007 |
Islet transplantation.
Topics: Diabetes Mellitus, Type 1; Follow-Up Studies; Glucagon; Humans; Hypoglycemia; Insulin; Insulin Secretion; Islets of Langerhans Transplantation; Treatment Failure | 2007 |
Reversal of defective glucagon responses to hypoglycemia in insulin-dependent autoimmune diabetic BB rats.
Topics: Animals; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Glucagon; Hypoglycemia; Insulin; Male; Rats; Rats, Inbred BB; Rats, Wistar | 2007 |
Plasma glucagon decreases during night-time sleep in Type 1 diabetic patients and healthy control subjects.
Topics: Adult; Blood Glucose; Case-Control Studies; Circadian Rhythm; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Insulin; Male; Polysomnography; Sleep | 2007 |
Metabolic follow-up after long-term pancreas graft survival.
Topics: Adult; Area Under Curve; Blood Glucose; Diabetes Mellitus, Type 1; Female; Follow-Up Studies; Glucagon; Glucose Tolerance Test; Glycated Hemoglobin; Graft Survival; Humans; Insulin; Male; Pancreas Transplantation; Prospective Studies; Statistics, Nonparametric | 2007 |
T-cell responses to islet antigens improves detection of autoimmune diabetes and identifies patients with more severe beta-cell lesions in phenotypic type 2 diabetes.
Topics: Adult; Aged; Antigens; Autoantibodies; C-Peptide; Cell Proliferation; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Glucose; Humans; Islets of Langerhans; Male; Middle Aged; Phenotype; T-Lymphocytes | 2007 |
Interdiction of the diabetic state in NOD mice by sustained induction of heme oxygenase: possible role of carbon monoxide and bilirubin.
Topics: Animals; bcl-X Protein; Bilirubin; Blood Glucose; Blotting, Western; Carbon Monoxide; CD11 Antigens; Dendritic Cells; Diabetes Mellitus, Type 1; Enzyme Activation; Female; Glucagon; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Immunohistochemistry; Insulin; Insulin-Secreting Cells; Mice; Mice, Inbred NOD; NADPH Oxidases; Pancreas; Proto-Oncogene Proteins c-akt; Protoporphyrins | 2007 |
Meal-stimulated glucagon release is associated with postprandial blood glucose level and does not interfere with glycemic control in children and adolescents with new-onset type 1 diabetes.
Topics: Adolescent; ATP-Binding Cassette Transporters; Blood Glucose; C-Peptide; Child; Cohort Studies; Diabetes Mellitus, Type 1; Eating; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Glycated Hemoglobin; Humans; Immunohistochemistry; Insulin-Secreting Cells; Male; Postprandial Period; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sulfonylurea Receptors | 2007 |
Co-localisation of the Kir6.2/SUR1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes.
Topics: Adolescent; ATP-Binding Cassette Transporters; Blotting, Western; C-Peptide; Child; Diabetes Mellitus, Type 1; Eating; Female; Gastric Inhibitory Polypeptide; Genotype; Glucagon; Glucagon-Like Peptide 1; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Ileum; Immunohistochemistry; Insulin; Islets of Langerhans; Male; Polymorphism, Restriction Fragment Length; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sulfonylurea Receptors | 2007 |
Possible role of alpha-cell insulin resistance in exaggerated glucagon responses to arginine in type 2 diabetes.
Topics: Adult; Aged; Area Under Curve; Arginine; Body Mass Index; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Insulin Resistance; Insulin-Secreting Cells; Japan; Male; Middle Aged; Reference Values | 2007 |
Editorial: The role of glucagon in postprandial hyperglycemia--the jury's still out.
Topics: Blood Glucose; C-Peptide; Child; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Glycated Hemoglobin; Humans; Hyperglycemia; Insulin; Postprandial Period; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Sulfonylurea Compounds | 2007 |
Postprandial paradoxical IGFBP-1 response in obese patients with Type 2 diabetes.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Insulin; Insulin-Like Growth Factor Binding Protein 1; Male; Middle Aged; Obesity; Postprandial Period; Somatostatin | 2008 |
Comparison of pancreas-transplanted type 1 diabetic patients with portal-venous versus systemic-venous graft drainage: impact on glucose regulatory hormones and the growth hormone/insulin-like growth factor-I axis.
Topics: Adult; C-Peptide; Diabetes Mellitus, Type 1; Drainage; Female; Glucagon; Glucose Tolerance Test; Human Growth Hormone; Humans; Insulin; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Male; Middle Aged; Pancreas Transplantation; Portal Vein | 2008 |
Effect of oral amino acids on counterregulatory responses and cognitive function during insulin-induced hypoglycemia in nondiabetic and type 1 diabetic people.
Topics: Administration, Oral; Adult; Amino Acids; Area Under Curve; Blood Glucose; C-Peptide; Cognition; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Humans; Hydrocortisone; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Norepinephrine; Pancreatic Polypeptide; Reference Values; Surveys and Questionnaires; Trail Making Test | 2008 |
Diabetes mellitus: customizing management.
Topics: Adult; Aging; Biguanides; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Dietary Fats; Dietary Fiber; Female; Glucagon; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Insulin; Insulin Resistance; Male; Monitoring, Physiologic; Pregnancy; Pregnancy in Diabetics; Sulfonylurea Compounds | 1984 |
No response of pancreatic hormones to hypoglycemia in diabetic autonomic neuropathy.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Glucagon; Heart Rate; Humans; Hypotension, Orthostatic; Insulin; Male; Pancreatic Hormones; Pancreatic Polypeptide; Somatostatin | 1982 |
Islet cell surface antibodies from insulin-dependent diabetics bind specifically to pancreatic B cells.
Topics: Adult; Animals; Autoantibodies; Binding Sites, Antibody; Diabetes Mellitus, Type 1; Fluorescent Antibody Technique; Glucagon; Humans; Islets of Langerhans; Male; Pancreatic Polypeptide; Rats; Rats, Inbred Strains; Receptor, Insulin; Receptors, Glucocorticoid; Somatostatin; Thyroiditis | 1982 |
[Immunocytochemical morphometry in type I and type II diabetes mellitus].
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; Humans; Immunochemistry; Insulin; Islets of Langerhans; Pancreatic Polypeptide; Somatostatin | 1983 |
Alterations in somatostatin and other islet cell functions in the spontaneously diabetic BB Wistar rat: biochemical and morphological characterization.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Fluorescent Antibody Technique; Glucagon; Insulin; Islets of Langerhans; Pancreas; Perfusion; Rats; Rats, Inbred Strains; Somatostatin | 1983 |
Spontaneous diabetes mellitus syndrome in the rat. III. Pancreatic alterations in aglycosuric and untreated diabetic BB Wistar-derived rats.
Topics: Age Factors; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Female; Glucagon; Glycosuria; Insulin; Male; Microscopy, Electron; Pancreas; Rats; Rats, Inbred Strains; Somatostatin | 1983 |
Effects of a long-acting somatostatin analogue on postprandial hyperglycemia in insulin-dependent diabetes mellitus.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Eating; Glucagon; Growth Hormone; Humans; Hyperglycemia; Insulin; Male; Somatostatin; Triglycerides; Xylose | 1983 |
Adrenergic blockade and hypoglycaemia.
Topics: Adrenergic beta-Antagonists; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Glucagon; Gluconeogenesis; Glycerol; Glycogen; Humans; Hypertension; Hypoglycemia; Insulin; Lactates; Lactic Acid; Liver; Metoprolol; Propranolol | 1983 |
Glomerular hyperfiltration after protein ingestion, during glucagon infusion, and in insulin-dependent diabetes is induced by a liver hormone: deficient production of this hormone in hepatic failure causes hepatorenal syndrome.
Topics: Amino Acids; Animals; Diabetes Mellitus, Type 1; Dietary Proteins; Glomerular Filtration Rate; Glucagon; Glucuronates; Hemodynamics; Humans; Kidney Failure, Chronic; Kidney Glomerulus; Liver; Liver Diseases; Models, Biological | 1984 |
Tolbutamide does not alter insulin requirement in Type 1 (insulin-dependent) diabetes.
Topics: Adult; C-Peptide; Diabetes Mellitus, Type 1; Drug Synergism; Fatty Acids, Nonesterified; Glucagon; Glycerol; Humans; Insulin Infusion Systems; Male; Middle Aged; Somatostatin; Tolbutamide | 1984 |
Increased energy expenditure in poorly controlled Type 1 (insulin-dependent) diabetic patients.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Energy Metabolism; Female; Glucagon; Humans; Hydrocortisone; Insulin; Male; Somatostatin; Triiodothyronine | 1984 |
Plasma beta-thromboglobulin response to insulin-induced hypoglycemia in type I diabetic patients.
Topics: Adolescent; Adult; Beta-Globulins; beta-Thromboglobulin; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Middle Aged | 1984 |
Adrenergic blockade alters glucose kinetics during exercise in insulin-dependent diabetics.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Humans; Insulin; Kinetics; Male; Norepinephrine; Phentolamine; Physical Exertion; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Tritium | 1984 |
Identification of type I diabetic patients at increased risk for hypoglycemia during intensive therapy.
Topics: Adolescent; Adult; Blood Glucose; Child; Diabetes Mellitus, Type 1; Glucagon; Homeostasis; Humans; Hypoglycemia; Infusions, Parenteral; Insulin; Middle Aged; Norepinephrine; Risk | 1983 |
Clinical forms and natural history of the diabetic syndrome and insulin and glucagon secretion in the BB rat.
Topics: Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Female; Glucagon; Insulin; Insulin Secretion; Male; Rats; Rats, Inbred Strains; Stress, Physiological; Tolbutamide | 1983 |
[The diagnostic value of serum C-peptide determination].
Topics: Adolescent; Adult; Aged; C-Peptide; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Insulin; Male; Middle Aged; Peptides | 1983 |
The Berson memorial lecture. Insulin-glucagon relationships in the defense against hypoglycemia.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Insulin; Islets of Langerhans; Microcirculation; Models, Biological; Physical Exertion; Sympathetic Nervous System | 1983 |
[Recent knowledge on the biochemistry and function of insulin and the effects of insufficient secretion and activity of the hormone].
Topics: Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Energy Metabolism; Glucagon; Humans; Insulin; Lipids; Liver; Proinsulin; Receptor, Insulin | 1983 |
Effect of insulin replacement on intermediary metabolism in diabetes secondary to pancreatectomy.
Topics: Adult; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Glucagon; Gluconeogenesis; Humans; Injections, Subcutaneous; Insulin; Insulin Infusion Systems; Pancreatectomy; Pancreatic Function Tests | 1983 |
Glucagon deficiency associated with hypoglycaemia and the absence of islet cell antibodies in the polyglandular failure syndrome before the onset of insulin-dependent diabetes mellitus: a case report.
Topics: Adrenal Insufficiency; Adult; Amino Acids; Arginine; Autoantibodies; Diabetes Mellitus, Type 1; Endocrine System Diseases; Fasting; Female; Glucagon; Humans; Hypoglycemia; Hypopituitarism; Hypothyroidism; Insulin; Islets of Langerhans | 1983 |
Responses to continuous and intermittent exercise in healthy and insulin-dependent diabetic children.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adolescent; Blood Glucose; Butyrates; Child; Diabetes Mellitus, Type 1; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hydroxybutyrates; Insulin; Male; Oxygen Consumption; Physical Exertion | 1983 |
Residual C-peptide production in type I diabetes mellitus. A comparison of different methods of assessment and influence on glucose control.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Glycated Hemoglobin; Humans; Insulin; Lipids; Male | 1983 |
Ultrastructural, immunohistological, and clinical findings in the pancreas in insulin-dependent diabetes mellitus (IDDM) of long duration.
Topics: Aged; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Humans; Islets of Langerhans; Male; Microscopy, Electron; Middle Aged; Pancreas | 1983 |
Anti-pancreatic immunity. In vitro studies of cellular and humoral immune reactions directed toward pancreatic islets.
Topics: Adolescent; Adult; Aged; Animals; Cells, Cultured; Child; Child, Preschool; Complement System Proteins; Cytotoxicity, Immunologic; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Immunoglobulins; Insulin; Insulin Secretion; Islets of Langerhans; Lymphocytes; Male; Mice; Mice, Inbred Strains; Middle Aged | 1984 |
Effects of long-term optimization and short-term deterioration of glycemic control on glucose counterregulation in type I diabetes mellitus.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose; Humans; Hypoglycemia; Insulin; Male | 1984 |
Mechanisms of glucagon secretion during insulin-induced hypoglycemia in man. Role of the beta cell and arterial hyperinsulinemia.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Glucagon; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Islets of Langerhans | 1984 |
The Somogyi phenomenon. Sacred cow or bull?
Topics: Adolescent; Adult; Blood Glucose; Child; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Epinephrine; Food; Glucagon; Humans; Hydrocortisone; Hyperglycemia; Hypoglycemia; Insulin | 1984 |
[Basal C-peptide determination or glucagon stimulation test in the choice of treatment of diabetes mellitus?].
Topics: Adolescent; Adult; Aged; Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Middle Aged; Peptides | 1984 |
Studies on the pathogenesis of the dawn phenomenon in insulin-dependent diabetic patients.
Topics: Adult; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Infusions, Parenteral; Insulin; Male; Metabolic Clearance Rate; Norepinephrine | 1984 |
Anti-glucagon-cell and anti-adrenal-medullary-cell antibodies in islet-cell-autoantibody-positive diabetic children.
Topics: Adolescent; Adrenal Medulla; Autoantibodies; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Islets of Langerhans; Male | 1984 |
Pancreatic alpha cell autoantibodies and glucagon response to arginine.
Topics: Adrenal Glands; Adult; Arginine; Autoantibodies; Diabetes Mellitus, Type 1; Female; Glucagon; Histocompatibility Antigens Class II; HLA-DR3 Antigen; HLA-DR4 Antigen; Humans; Islets of Langerhans; Male; Middle Aged; Parietal Cells, Gastric; Thyroid Gland | 1984 |
Differential sensitivity to beta-cell secretagogues in "early," type I diabetes mellitus.
Topics: Arginine; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Tolbutamide | 1984 |
Abnormal glucose counterregulation after subcutaneous insulin in insulin-dependent diabetes mellitus.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Injections, Subcutaneous; Insulin; Insulin Antibodies; Male | 1984 |
Improved but not normalized glucose counter-regulation during glucagon infusion in Type 1 (insulin-dependent) diabetes.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Humans; Hypoglycemia; Insulin; Male; Norepinephrine | 1984 |
A reliable and reproducible test for adequate glucose counterregulation in type I diabetes mellitus.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Middle Aged; Risk | 1984 |
Effect of epinephrine on glucose metabolism in humans: contribution of the liver.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Glucose; Humans; Insulin; Intestinal Absorption; Kinetics; Liver; Time Factors | 1984 |
A double-blind study of the efficacy of neutral human and porcine insulin in type I diabetes using a glucose-controlled insulin infusion system.
Topics: Adult; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Double-Blind Method; Glucagon; Glucose Tolerance Test; Growth Hormone; Humans; Insulin; Insulin Infusion Systems; Male; Middle Aged; Species Specificity; Swine | 1984 |
Time course of serum glucoregulatory variables and lipids following neonatal thymectomy of diabetes-prone and control BB Wistar rats fed a defined diet.
Topics: Animals; Animals, Newborn; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Food, Formulated; Glucagon; Insulin; Male; Rats; Rats, Inbred Strains; Thymectomy | 1984 |
Short-term of the artificial beta-cell (Biostator) on pancreatic glucagon response in insulin-dependent diabetic (IDDM).
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glucagon; Glucose; Glycerol; Humans; Insulin; Insulin Infusion Systems; Insulin Secretion; Male; Pancreas; Time Factors | 1984 |
[The pancreatic reserve in diabetes mellitus by the determination of serum C-peptide using radioimmunoassay].
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Insulin; Male; Pancreas; Radioimmunoassay | 1984 |
Lack of negative feed-back regulation of insulin on the responses of gastric inhibitory polypeptide, insulin, glucagon and pancreatic polypeptide to a meal in insulin treated diabetics.
Topics: Adult; Aged; C-Peptide; Diabetes Mellitus, Type 1; Female; Food; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Homeostasis; Humans; Insulin; Male; Middle Aged; Pancreatic Polypeptide | 1984 |
Glucose counterregulation and waning of insulin in the Somogyi phenomenon (posthypoglycemic hyperglycemia).
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Insulin; Insulin Resistance; Male; Norepinephrine | 1984 |
Lack of relationship between plasma insulin and glucagon levels and angiographically-documented coronary atherosclerosis.
Topics: Blood Glucose; Cardiac Catheterization; Cholesterol; Coronary Angiography; Coronary Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Insulin; Male; Middle Aged; Triglycerides | 1984 |
Glucose counterregulation in patients after pancreatectomy. Comparison with other clinical forms of diabetes.
Topics: Adult; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Epinephrine; Female; Glucagon; Humans; Hypoglycemia; Insulin; Male; Middle Aged; Pancreatectomy | 1984 |
Plasma glucagon suppressibility after oral glucose in obese subjects with normal and impaired glucose tolerance.
Topics: Administration, Oral; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Male; Middle Aged; Obesity; Radioimmunoassay | 1984 |
Duration of type I diabetes affects glucagon and glucose responses to insulin-induced hypoglycemia.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemia; Insulin; Male; Prognosis; Time Factors | 1984 |
Glucagon and insulin hypoglycaemia.
Topics: Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Insulin | 1984 |
Beta-cell function recovery is not the only factor responsible for remission in type I diabetics: evaluation of C-peptide secretion in diabetic children after first metabolic recompensation and at partial remission phase.
Topics: Adolescent; Arginine; C-Peptide; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Islets of Langerhans; Male; Time Factors | 1984 |
A mechanism by which primary or secondary hypothalamic involvement results in the development of insulin-dependent diabetes mellitus (IDDM).
Topics: Adrenal Medulla; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Dogs; Glucagon; Growth Hormone; Homeostasis; Humans; Hypothalamus; Insulin; Models, Biological; Rats | 1984 |
[Islet beta-cell function in failures following sulfonylurea therapy in diabetics, by determination of serum C-peptide].
Topics: Adult; Aged; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Islets of Langerhans; Male; Middle Aged; Sulfonylurea Compounds | 1984 |
Suppressible glucagon secretion in young, ketosis-resistant, type "J" diabetic patients in India.
Topics: Adolescent; Adult; Blood Glucose; Child; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Fatty Acids, Nonesterified; Glucagon; Glucose Tolerance Test; Humans; India; Insulin | 1983 |
Diagnosis and management of diabetes mellitus in children.
Topics: Blood Glucose; Child; Combined Modality Therapy; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Diet, Diabetic; Female; Glucagon; Glycosuria; Humans; Insulin; Male; Prognosis | 1984 |
Hypoglycemic episodes during continuous subcutaneous insulin infusion: decreased frequency but increased susceptibility.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin Infusion Systems; Male; Middle Aged | 1984 |
Evaluation of a sensitive and specific radioimmunoassay for pancreatic glucagon in human plasma and its clinical application.
Topics: Acromegaly; Adolescent; Adult; Arginine; Cushing Syndrome; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Humans; Male; Middle Aged; Obesity; Radioimmunoassay | 1984 |
Turnover and splanchnic metabolism of free fatty acids and ketones in insulin-dependent diabetics at rest and in response to exercise.
Topics: Adult; Carbon Radioisotopes; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Growth Hormone; Humans; Ketone Bodies; Male; Mesentery; Middle Aged; Norepinephrine; Oleic Acid; Oleic Acids; Physical Exertion; Rest | 1984 |
Physical training in juvenile diabetes.
Topics: Adult; Animals; Blood Glucose; Catecholamines; Diabetes Mellitus, Type 1; Glucagon; Growth Hormone; Humans; Injections, Intramuscular; Insulin; Physical Education and Training; Rats | 1982 |
[Roles of endogenous insulin reserve and the counter-regulatory hormones in the various phases of juvenile diabetes mellitus].
Topics: Adolescent; Age Factors; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Glycated Hemoglobin; Humans; Hydrocortisone; Insulin; Insulin Secretion | 1982 |
Importance of glucose control for the recovery from hypoglycemia in insulin-dependent diabetics.
Topics: Adult; Blood Glucose; Catecholamines; Diabetes Mellitus, Type 1; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Middle Aged | 1982 |
Preoperative evaluation of pancreatic transplant recipients.
Topics: Arginine; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Islets of Langerhans Transplantation; Prognosis | 1980 |
Acute diabetic ketoacidosis in children: role of the stress hormones.
Topics: Acute Disease; Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Epinephrine; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Insulin; Male; Norepinephrine | 1981 |
Effect of intravenous alanine on blood glucose, glucagon and growth hormone levels in diabetic children.
Topics: Adolescent; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Glucagon; Growth Hormone; Humans; Stimulation, Chemical | 1982 |
Metabolic responses to hypoglycemia in juvenile diabetics.
Topics: Adult; Autonomic Nervous System Diseases; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Fatty Acids, Nonesterified; Glucagon; Humans; Hypoglycemia; Male | 1980 |
Altered responsiveness to cortisol, epinephrine, and glucagon in insulin-infused juvenile-onset diabetics. A mechanism for diabetic instability.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Humans; Hydrocortisone; Insulin; Kinetics; Male; Norepinephrine | 1980 |
Effects of acetylsalicylic acid on blood glucose, plasma FFA, glycerol, 3-hydroxybutyrate, alanine, C-peptide, glucagon and growth hormone responses to arginine in insulin-dependent diabetics.
Topics: Adolescent; Adult; Alanine; Arginine; Aspirin; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Glycerol; Growth Hormone; Hormones; Humans; Hydroxybutyrates; Insulin; Male; Middle Aged | 1980 |
C-Peptide reserve in insulin-dependent diabetes. Comparative responses to glucose, glucagon and tolbutamide.
Topics: Adolescent; Adult; Blood Glucose; C-Peptide; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Islets of Langerhans; Kinetics; Male; Peptides; Tolbutamide | 1980 |
Epinephrine-induced hypoaminoacidemia in normal and diabetic human subjects: effect of beta blockade.
Topics: Adult; Amino Acids; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Humans; Insulin; Kinetics; Male; Propranolol; Reference Values | 1980 |
Epinephrine and the regulation of glucose metabolism: effect of diabetes and hormonal interactions.
Topics: Adult; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Dogs; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Humans; Hydrocortisone; Insulin; Ketone Bodies; Liver; Metabolic Clearance Rate | 1980 |
Failure of cortisol blockade to inhibit early morning increases in basal insulin requirements in fasting insulin-dependent diabetics.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Fasting; Glucagon; Growth Hormone; Humans; Hydrocortisone; Insulin; Time Factors | 1980 |
Hyperkalemia and hyperglycemic increments in plasma potassium in diabetes mellitus.
Topics: Adolescent; Adult; Aged; Blood Glucose; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Humans; Hypercalcemia; Hyperglycemia; Hyperkalemia; Insulin; Male; Middle Aged; Norepinephrine; Potassium | 1980 |
[The significance of insulin secretion in the pathogenesis of diabetes mellitus].
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Tolbutamide | 1981 |
[Investigation of insulin resistance in fourteen children starting a diabetes mellitus (author's transl)].
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Fatty Acids; Female; Glucagon; Humans; Hydrocortisone; Insulin; Insulin Resistance; Male; Triglycerides | 1981 |
Complement-fixing Islet cell antibodies from some diabetic patients alter insulin release in vitro.
Topics: Adolescent; Adult; Aged; Animals; Antibody Formation; Arginine; Biological Assay; Child; Complement Fixation Tests; Diabetes Mellitus, Type 1; Female; Fluorescent Antibody Technique; Glucagon; Humans; Insulin; Islets of Langerhans; Male; Mice; Middle Aged | 1981 |
Relationship of glycosylated haemoglobin to C-peptide secretory status and antibody binding of insulin in insulin-dependent diabetes.
Topics: Adolescent; Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Glycated Hemoglobin; Humans; Insulin; Insulin Antibodies; Male; Peptides | 1981 |
Effects of pharmacologic hyperglucagonemia on plasma amino acid concentrations in normal and diabetic man.
Topics: Amino Acids; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Male; Time Factors | 1981 |
Endocrine pancreatic response of children with onset of insulin-requiring diabetes before age 3 and after age 5.
Topics: Arginine; Blood Glucose; C-Peptide; Child; Child, Preschool; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Gastric Inhibitory Polypeptide; Glucagon; Humans; Hypoglycemia; Infant; Infusions, Parenteral; Insulin; Islets of Langerhans; Male; Pancreatic Polypeptide; Time Factors | 1982 |
Insulin antibodies in juvenile diabetes mellitus. Correlations to diabetic stability, insulin requirement and duration of insulin treatment.
Topics: Adolescent; Blood Glucose; Diabetes Mellitus, Type 1; Fasting; Glucagon; Humans; Insulin; Insulin Antibodies; Prognosis; Time Factors | 1982 |
Relation of counterregulatory responses to hypoglycemia in type I diabetics.
Topics: Adolescent; Adult; Autonomic Nervous System; Blood Glucose; Child, Preschool; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Male; Norepinephrine | 1982 |
Increased growth hormone response to dopamine infusion in insulin-dependent diabetic subjects: indication of possible blood-brain barrier abnormality.
Topics: Adult; Apomorphine; Blood-Brain Barrier; Capillary Permeability; Diabetes Mellitus, Type 1; Dopamine; Female; Glucagon; Growth Hormone; Humans; Infusions, Parenteral; Insulin; Physical Exertion | 1980 |
Impaired responses of catecholamines, growth hormone, and cortisol to graded exercise in diabetic autonomic neuropathy.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Glycerol; Growth Hormone; Heart Rate; Humans; Hydrocortisone; Hydroxybutyrates; Lactates; Norepinephrine; Physical Exertion | 1980 |
The effect of glucagon infusion on kidney function in short-term insulin-dependent juvenile diabetics.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Glomerular Filtration Rate; Glucagon; Humans; Kidney; Regional Blood Flow | 1980 |
[Management of the insulin-dependent diabetic in ambulatory practice: the first year].
Topics: Adolescent; Adult; Ambulatory Care; Blood Glucose; Child; Diabetes Mellitus, Type 1; Family Practice; Glucagon; Hospitalization; Humans; Insulin; Patient Care Planning; Patient Education as Topic | 1995 |
Glucagon stimulates insulin-like growth factor binding protein-1 secretion in healthy subjects, patients with pituitary insufficiency, and patients with insulin-dependent diabetes mellitus.
Topics: Adult; Carrier Proteins; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; Humans; Hyperglycemia; Insulin; Insulin-Like Growth Factor Binding Protein 1; Male; Middle Aged; Reference Values; Somatomedins | 1993 |
Effect of insulin on the hepatic production of insulin-like growth factor-binding protein-1 (IGFBP-1), IGFBP-3, and IGF-I in insulin-dependent diabetes.
Topics: Adult; Carrier Proteins; Diabetes Mellitus, Type 1; Glucagon; Glucose; Hepatic Veins; Humans; Insulin; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Kinetics; Liver; Male; Splanchnic Circulation | 1994 |
Hypoglycaemic threshold after pancreatic transplantation.
Topics: Adult; Awareness; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Growth Hormone; Humans; Hypoglycemia; Insulin; Pancreas Transplantation | 1995 |
Characterization of insulin-dependent diabetes mellitus induced by a new variant (DK-27) of encephalomyocarditis virus in DBA/2 mice.
Topics: Animals; Blood Glucose; Cardiovirus Infections; Diabetes Mellitus, Type 1; Disease Models, Animal; Encephalomyocarditis virus; Glucagon; Glycated Hemoglobin; Hyperglycemia; Insulin; Male; Mice; Mice, Inbred DBA; Pancreas; Virus Replication | 1995 |
Chronic calcific pancreatitis of the tropics (CCPT): spectrum and correlates of exocrine and endocrine pancreatic dysfunction.
Topics: Adolescent; Adult; Age of Onset; Analysis of Variance; Blood Glucose; C-Peptide; Calcinosis; Chronic Disease; Chymotrypsin; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Islets of Langerhans; Male; Pancreas; Pancreatitis; Reference Values; Tropical Climate; Ultrasonography | 1995 |
Brainstem dysfunction is provoked by a less pronounced hypoglycemic stimulus in diabetic BB rats.
Topics: Animals; Brain Stem; Diabetes Mellitus, Type 1; Epinephrine; Evoked Potentials, Auditory; Glucagon; Glycated Hemoglobin; Humans; Hypoglycemia; Inferior Colliculi; Insulin; Male; Norepinephrine; Rats; Rats, Inbred BB; Reference Values; Time Factors | 1995 |
Lipid and carbohydrate metabolism in IDDM during moderate and intense exercise.
Topics: Adult; Blood Glucose; Calorimetry; Carbohydrate Metabolism; Diabetes Mellitus, Type 1; Exercise; Fatty Acids, Nonesterified; Glucagon; Glucose; Glycerol; Humans; Insulin; Lactates; Lipid Metabolism; Male; Norepinephrine; Oxygen Consumption; Physical Exertion; Reference Values; Rest; Time Factors | 1995 |
Islet cell antibodies: variable immunostaining of pancreatic islet cells and carcinoid tissue.
Topics: Adolescent; Adult; Aged; Autoantibodies; Carcinoid Tumor; Diabetes Mellitus, Type 1; Female; Fluorescent Antibody Technique; Glucagon; Glutamate Decarboxylase; Humans; Immunoenzyme Techniques; Islets of Langerhans; Male; Middle Aged; Pancreatic Neoplasms; Precipitin Tests; Stiff-Person Syndrome | 1995 |
Differential regulation of counterregulatory hormone secretion and symptoms during hypoglycemia in IDDM. Effect of glycemic control.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Male; Radioimmunoassay | 1995 |
Exercise-induced hypoglycaemia in IDDM patients treated with a short-acting insulin analogue.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Exercise; Female; Glucagon; Humans; Hypoglycemia; Insulin; Male | 1995 |
Natural course of insulin sensitivity and insulin reserve in early insulin-dependent diabetes mellitus.
Topics: Adult; Arginine; Blood Glucose; C-Peptide; Case-Control Studies; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Clamp Technique; Glycated Hemoglobin; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Longitudinal Studies; Male; Reference Values; Regression Analysis; Time Factors | 1995 |
Failure of glucagon suppression contributes to postprandial hyperglycaemia in IDDM.
Topics: Adult; Blood Glucose; Carbon Radioisotopes; Diabetes Mellitus, Type 1; Dietary Carbohydrates; Eating; Female; Glucagon; Glucose; Humans; Hyperglycemia; Infusions, Intravenous; Insulin; Kinetics; Liver; Male; Portal System; Radioisotope Dilution Technique; Somatostatin; Time Factors; Tritium | 1995 |
Glucagon-like peptide I reduces postprandial glycemic excursions in IDDM.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Eating; Female; Glucagon; Glucagon-Like Peptide 1; Humans; Infusions, Intravenous; Insulin; Male; Peptide Fragments; Protein Precursors | 1995 |
Modified glucagon test allowing simultaneous estimation of insulin secretion and insulin sensitivity: application to obesity, insulin-dependent diabetes mellitus, and noninsulin-dependent diabetes mellitus.
Topics: Adult; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Insulin; Insulin Resistance; Insulin Secretion; Male; Obesity | 1995 |
Transgenic mice expressing constitutive levels of IL-2 in islet beta cells develop diabetes.
Topics: Animals; B-Lymphocytes; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Line; Cells, Cultured; Diabetes Mellitus, Type 1; Glucagon; Glucose; Immunoenzyme Techniques; Immunotherapy, Adoptive; Interleukin-2; Islets of Langerhans; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Transgenic | 1994 |
Hypoglycemia unawareness in IDDM.
Topics: Adult; Autonomic Nervous System; Awareness; Blood Glucose; Catecholamines; Cognition; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Clamp Technique; Humans; Hypoglycemia; Infusions, Intravenous; Insulin; Male | 1994 |
Persistence of counter-regulatory abnormalities in insulin-dependent diabetes mellitus after pancreas transplantation.
Topics: Adult; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose; Growth Hormone; Humans; Hypoglycemia; Infusions, Intravenous; Insulin; Kidney Failure, Chronic; Kidney Transplantation; Male; Pancreas Transplantation; Postoperative Period | 1994 |
Preservation of GLUT 2 expression in islet beta cells of Kilham rat virus (KRV)-infected diabetes-resistant BB/Wor rats.
Topics: Animals; Diabetes Mellitus, Type 1; Female; Gene Expression; Glucagon; Glucose Transporter Type 2; Immunity, Innate; Immunohistochemistry; Insulin; Islets of Langerhans; Male; Monosaccharide Transport Proteins; Pancreatic Diseases; Parvoviridae Infections; Parvovirus; Rats; Rats, Inbred BB; Reference Values | 1994 |
Defective insulin and glucagon secretion in isolated perfused pancreata of diabetic WBN/Kob rats.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Susceptibility; Glucagon; Glucose Tolerance Test; In Vitro Techniques; Insulin; Insulin Secretion; Male; Pancreas; Perfusion; Rats; Rats, Inbred Strains; Rats, Wistar | 1995 |
Restoration of hypoglycaemia awareness in patients with long-duration insulin-dependent diabetes.
Topics: Adult; Awareness; Blood Glucose; Cognition; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Glucose Clamp Technique; Growth Hormone; Humans; Hypoglycemia; Insulin; Male; Middle Aged; Norepinephrine | 1994 |
Reversal of hypoglycemia unawareness, but not defective glucose counterregulation, in IDDM.
Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Awareness; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Clamp Technique; Glycated Hemoglobin; Growth Hormone; Humans; Hydrocortisone; Hydroxybutyrates; Hypoglycemia; Insulin; Lactates; Lactic Acid; Male; Norepinephrine; Pancreatic Polypeptide | 1994 |
A new method for comparing portal and peripheral venous insulin delivery in humans: tolbutamide versus insulin infusion.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Clamp Technique; Humans; Infusions, Intravenous; Insulin; Insulin Secretion; Kinetics; Male; Middle Aged; Portal Vein; Tolbutamide; Veins | 1994 |
Hormonal, metabolic, and circulatory responses to insulin-induced hypoglycemia in pregnant and nonpregnant women with insulin-dependent diabetes.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Circulation; Blood Glucose; Blood Pressure; Catecholamines; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Glycerol; Heart Rate; Humans; Hydrocortisone; Hydroxybutyrates; Hypoglycemia; Insulin; Lipids; Norepinephrine; Pregnancy; Pregnancy in Diabetics; Pregnancy Trimester, Third | 1994 |
An improved method for the determination of islet amyloid polypeptide levels in plasma.
Topics: Amyloid; C-Peptide; Cross Reactions; Diabetes Mellitus, Type 1; Glucagon; Humans; Injections, Intravenous; Islet Amyloid Polypeptide; Islets of Langerhans; Radioimmunoassay | 1994 |
Hormonal enteroinsular axis in newborn infants of insulin-treated diabetic mothers.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Digestive System; Enteral Nutrition; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptides; Humans; Infant, Newborn; Insulin; Islets of Langerhans; Male; Milk, Human; Pancreas; Pregnancy; Pregnancy in Diabetics | 1993 |
Chromostatin, a chromogranin A-derived bioactive peptide, is present in human pancreatic insulin (beta) cells.
Topics: Adrenal Medulla; Chromogranin A; Chromogranins; Diabetes Mellitus, Type 1; Glucagon; Humans; Immune Sera; Immunohistochemistry; Insulin; Insulinoma; Islets of Langerhans; Microscopy, Immunoelectron; Pancreas; Pancreatic Neoplasms; Pancreatic Polypeptide; Peptide Fragments; Somatostatin | 1993 |
Induction of type I diabetes by interferon-alpha in transgenic mice.
Topics: Animals; Antibodies, Monoclonal; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; Diabetes Mellitus, Type 1; Female; Glucagon; Insulin; Interferon-alpha; Islets of Langerhans; Leukocytes, Mononuclear; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neutralization Tests; Somatostatin | 1993 |
[Effects of insular hormones on the secretion of atrial natriuretic factor].
Topics: Adolescent; Adult; Atrial Natriuretic Factor; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Hyperinsulinism; Insulin; Male; Middle Aged; Obesity; Potassium; Secretory Rate; Sodium | 1993 |
Contributory roles of circulatory glucagon and growth hormone to increased renal haemodynamics in type 1 (insulin-dependent) diabetes mellitus.
Topics: Adult; Diabetes Mellitus, Type 1; Exercise Test; Female; Glucagon; Growth Hormone; Hemodynamics; Humans; Insulin-Like Growth Factor I; Kidney; Male; Middle Aged | 1993 |
Renal morphological changes in dogs with systemic venous drainage of the pancreas.
Topics: Animals; Arginine; Blood Glucose; Creatinine; Diabetes Mellitus, Type 1; Dogs; Glucagon; Insulin; Kidney; Kidney Transplantation; Pancreas; Pancreas Transplantation; Regional Blood Flow; Veins | 1994 |
Effect of hyperglycaemia on gallbladder motility in type 1 (insulin-dependent) diabetes mellitus.
Topics: Adult; Blood Glucose; Cholecystokinin; Diabetes Mellitus, Type 1; Female; Gallbladder; Glucagon; Glucose Clamp Technique; Humans; Hyperglycemia; Infusions, Intravenous; Male; Muscle Contraction; Muscle, Smooth; Pancreatic Polypeptide; Reference Values; Ultrasonography | 1994 |
Pharmacokinetics of intranasal, intramuscular and intravenous glucagon in healthy subjects and diabetic patients.
Topics: Administration, Intranasal; Adult; Diabetes Mellitus, Type 1; Glucagon; Half-Life; Humans; Infusions, Intravenous; Injections, Intramuscular | 1993 |
Pancreas transplantation in diabetic humans normalizes hepatic glucose production during hypoglycemia.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Gluconeogenesis; Glucose; Glucose Clamp Technique; Humans; Hypoglycemia; Immunosuppressive Agents; Infusions, Intravenous; Insulin; Kidney Transplantation; Liver; Male; Pancreas Transplantation; Reference Values | 1994 |
Beta-cell dysfunction following successful segmental pancreas transplantation. Danish-Swedish Study Group of Metabolic Effect of Pancreas Transplantation.
Topics: Arginine; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Eating; Glucagon; Humans; Immunosuppression Therapy; Islets of Langerhans; Pancreas Transplantation; Reference Values | 1994 |
Glucose clamp investigations. The ups and downs.
Topics: Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Glucose Clamp Technique; Homeostasis; Humans; Insulin; Insulin Secretion | 1994 |
Hypoglycemia-induced autonomic failure in IDDM is specific for stimulus of hypoglycemia and is not attributable to prior autonomic activation.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Analysis of Variance; Autonomic Nervous System; Blood Glucose; Blood Pressure; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Clamp Technique; Growth Hormone; Heart Rate; Humans; Hydrocortisone; Hydroxybutyrates; Hypoglycemia; Insulin; Lactates; Male; Norepinephrine; Oxygen Consumption; Pancreatic Polypeptide; Physical Exertion; Posture; Reference Values; Time Factors | 1994 |
Exaggerated epinephrine response to hypoglycemia in a physically fit, well-controlled IDDM subject.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Blood Pressure; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Fatty Acids, Nonesterified; Glucagon; Growth Hormone; Heart Rate; Humans; Hydrocortisone; Hydroxybutyrates; Hypoglycemia; Insulin; Lactates; Liver; Male; Pancreatic Polypeptide; Physical Fitness; Reference Values; Sports | 1994 |
Characteristics of severe hypoglycemia in the patient with insulin-dependent diabetes.
Topics: Adult; Blood Glucose Self-Monitoring; Confusion; Diabetes Mellitus, Type 1; Diabetic Coma; Diabetic Nephropathies; Diabetic Neuropathies; Eating; Glucagon; Glucose; Glycated Hemoglobin; Humans; Hypoglycemia; Insulin; Physical Exertion; Risk Factors; Seasons; Seizures | 1994 |
Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients.
Topics: Adolescent; Adult; Autoimmunity; B-Lymphocytes; Biopsy; CD3 Complex; CD4 Antigens; CD8 Antigens; Cell Adhesion Molecules; Cell Movement; Diabetes Mellitus, Type 1; Female; Fluorescent Antibody Technique; Glucagon; Humans; Islets of Langerhans; Leukocytes, Mononuclear; Major Histocompatibility Complex; Male; Middle Aged; Pancreas; Pancreatitis; T-Lymphocyte Subsets; T-Lymphocytes | 1993 |
Impaired hormonal responses to hypoglycemia in spontaneously diabetic and recurrently hypoglycemic rats. Reversibility and stimulus specificity of the deficits.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Homeostasis; Hypoglycemia; Insulin; Male; Rats; Rats, Inbred BB; Reference Values; Time Factors | 1993 |
Hepatic glucose production during intraperitoneal and intravenous closed-loop insulin regulation of blood glucose in type 1 (insulin-dependent) diabetic patients.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glucagon; Gluconeogenesis; Glucose; Glucose Clamp Technique; Glycerol; Growth Hormone; Homeostasis; Humans; Hydrocortisone; Hydroxybutyrates; Insulin; Insulin Infusion Systems; Liver; Male; Middle Aged | 1993 |
The use of insulin in diabetes mellitus.
Topics: Amino Acid Sequence; Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Molecular Sequence Data | 1993 |
Lack of effect of hyperglycemia on lipolysis in humans.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Clamp Technique; Growth Hormone; Humans; Hyperglycemia; Insulin; Lipolysis; Male; Palmitic Acid; Palmitic Acids; Radioimmunoassay; Time Factors | 1993 |
Physiological, symptomatic and hormonal responses to acute hypoglycaemia in type 1 diabetic patients with autonomic neuropathy.
Topics: Adult; Awareness; Blood Glucose; C-Peptide; Cardiovascular System; Cognition; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Diarrhea; Epinephrine; Female; Glucagon; Glycated Hemoglobin; Heart Rate; Humans; Hypoglycemia; Hypotension, Orthostatic; Insulin; Male; Middle Aged; Pancreatic Polypeptide; Reaction Time; Sweating; Valsalva Maneuver | 1993 |
Beta-cell function in relation to islet cell antibodies during the first 3 yr after clinical diagnosis of diabetes in type II diabetic patients.
Topics: Adolescent; Adult; Age Factors; Autoantibodies; Body Mass Index; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fasting; Follow-Up Studies; Glucagon; Glycated Hemoglobin; Humans; Insulin; Islets of Langerhans; Middle Aged; Reference Values; Time Factors | 1993 |
The effect of recombinant human growth hormone on regulation of growth hormone secretion and blood glucose in insulin-dependent diabetes.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Insulin-Like Growth Factor I; Male; Recombinant Proteins | 1993 |
Preserved incretin effect in type 1 diabetic patients with end-stage nephropathy treated by combined heterotopic pancreas and kidney transplantation.
Topics: Adult; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose; Humans; Insulin; Insulin Secretion; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Pancreas Transplantation; Peptide Fragments; Protein Precursors; Radioimmunoassay; Reference Values; Transplantation, Heterotopic | 1993 |
No pharmacokinetic effect of retaining the infusion site up to four days during continuous subcutaneous insulin infusion therapy.
Topics: Adult; Blood Glucose; C-Peptide; Catheters, Indwelling; Diabetes Mellitus, Type 1; Glucagon; Glycated Hemoglobin; Humans; Insulin; Insulin Infusion Systems; Middle Aged; Time Factors | 1993 |
Acute insulin response to glucose and glucagon in subjects at risk of developing type I diabetes.
Topics: Adolescent; Analysis of Variance; Autoantibodies; Diabetes Mellitus, Type 1; Follow-Up Studies; Glucagon; Glucose; Humans; Insulin; Islets of Langerhans; Kinetics; Nuclear Family; Prediabetic State; Risk Factors; Time Factors | 1993 |
Improvement in blunted glucagon response to insulin-induced hypoglycemia by strict glycemic control in diabetics.
Topics: Adolescent; Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Glycated Hemoglobin; Humans; Hypoglycemia; Insulin; Insulin Infusion Systems; Insulin Secretion; Male; Middle Aged; Reference Values; Time Factors | 1993 |
The prevalence of type 1 diabetes mellitus at follow-up of Swedish infants congenitally infected with cytomegalovirus.
Topics: Autoantibodies; C-Peptide; Cytomegalovirus; Cytomegalovirus Infections; Diabetes Mellitus, Type 1; Follow-Up Studies; Glucagon; Glucose Tolerance Test; Humans; Infant, Newborn; Islets of Langerhans; Male; Prevalence; Sweden | 1993 |
Alcohol intake impairs glucose counterregulation during acute insulin-induced hypoglycemia in IDDM patients. Evidence for a critical role of free fatty acids.
Topics: Acute Disease; Adult; Alcohol Drinking; Blood Glucose; Catecholamines; Diabetes Mellitus, Type 1; Ethanol; Fatty Acids, Nonesterified; Glucagon; Glucose; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Lactates; Lipolysis; Male | 1993 |
Meticulous prevention of hypoglycemia normalizes the glycemic thresholds and magnitude of most of neuroendocrine responses to, symptoms of, and cognitive function during hypoglycemia in intensively treated patients with short-term IDDM.
Topics: Adult; Awareness; Blood Glucose; Cognition; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glycated Hemoglobin; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Male; Norepinephrine; Time Factors | 1993 |
Restoration of fuel homeostasis in IDDM patients during pregnancy by an open-loop insulin infusion system.
Topics: Adult; Blood Glucose; C-Peptide; Calorimetry; Carbohydrate Metabolism; Diabetes Mellitus, Type 1; Energy Metabolism; Female; Glucagon; Homeostasis; Humans; Insulin; Insulin Infusion Systems; Ketone Bodies; Lactates; Pregnancy; Pregnancy in Diabetics; Pregnancy Trimester, First; Pyruvates | 1993 |
Defects in quantitative and qualitative beta-cell function following successful segmental pancreas transplantation. Danish-Swedish Study Group of Metabolic Effect of Pancreas Transplantation (DSSGMEPT).
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Eating; Fasting; Glucagon; Glycated Hemoglobin; Humans; Islets of Langerhans; Kidney Transplantation; Middle Aged; Pancreas Transplantation; Reference Values; Tolbutamide | 1993 |
Hypoglycemia-associated autonomic failure in insulin-dependent diabetes mellitus. Recent antecedent hypoglycemia reduces autonomic responses to, symptoms of, and defense against subsequent hypoglycemia.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Blood Pressure; Cognition; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Clamp Technique; Glycated Hemoglobin; Humans; Hydroxybutyrates; Hyperinsulinism; Hypoglycemia; Iatrogenic Disease; Insulin; Lactates; Male; Time Factors | 1993 |
Nocturnal versus diurnal hormonal counterregulation to hypoglycemia in type 1 (insulin-dependent) diabetic patients.
Topics: Adult; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Growth Hormone; Hormones; Humans; Hydrocortisone; Hypoglycemia; Male; Middle Aged; Norepinephrine | 1993 |
Loss of potentiating effect of hypoglycemia on the glucagon response to hyperaminoacidemia in IDDM.
Topics: Adult; Amino Acids; Amino Acids, Essential; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Clamp Technique; Humans; Hypoglycemia; Infusions, Intravenous; Insulin; Insulin Infusion Systems; Male; Reference Values | 1993 |
IDDM in rats induced by thymectomy and irradiation.
Topics: Animals; Atrophy; Diabetes Mellitus, Type 1; Female; Fluorescent Antibody Technique; Gamma Rays; Glucagon; Immunotherapy, Adoptive; Insulin; Islets of Langerhans; Lymphocytes; Male; Pancreas; Rats; Rats, Inbred Strains; Sex Characteristics; Spleen; Thymectomy; Time Factors; Whole-Body Irradiation | 1993 |
Exaggerated hyperglycemia after a pizza meal in well-controlled diabetes.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Eating; Fatty Acids, Nonesterified; Female; Food; Glucagon; Humans; Hyperglycemia; Insulin; Male; Time Factors | 1993 |
An analysis of the glucagon response to hypoglycaemia in patients with type 1 diabetes and in healthy subjects.
Topics: Adult; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glycated Hemoglobin; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Infusions, Intravenous; Insulin; Male; Norepinephrine; Reference Values; Sex Characteristics; Time Factors | 1993 |
Plasma concentration of islet amyloid polypeptide in healthy children and patients with insulin-dependent diabetes mellitus.
Topics: Adolescent; Amyloid; C-Peptide; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucagon; Glycated Hemoglobin; Humans; Islet Amyloid Polypeptide; Male | 1993 |
Diagnosis of naturally acquired type-I and type-II diabetes mellitus in cats.
Topics: Animals; Blood Glucose; Cat Diseases; Cats; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Insulin; Obesity | 1993 |
Quantitative immunohistochemical changes in the endocrine pancreas of nonobese diabetic (NOD) mice.
Topics: Animals; Diabetes Mellitus, Type 1; Female; Glucagon; Immunohistochemistry; Insulin; Islets of Langerhans; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Pancreatic Polypeptide; Somatostatin | 1995 |
Human fetal islet transplantation in IDDM patients: an 8-year experience.
Topics: Biomarkers; C-Peptide; CD4-CD8 Ratio; Diabetes Mellitus, Type 1; Fetal Tissue Transplantation; Glucagon; Glycated Hemoglobin; Graft Rejection; Humans; Insulin; Insulin Secretion; Interleukin-2; Islets of Langerhans Transplantation; Time Factors | 1995 |
Androgens and insulin resistance in type 1 diabetic men.
Topics: Adult; Calorimetry, Indirect; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glucagon; Glycogen Synthase; Growth Hormone; Humans; Hydrocortisone; Insulin; Insulin Resistance; Insulin-Like Growth Factor Binding Protein 1; Lipid Peroxidation; Male; Muscle, Skeletal; Sex Hormone-Binding Globulin; Testosterone | 1995 |
Diabetes mellitus associated with pancreatic endocrine insufficiency in a kitten.
Topics: Amyloid; Animals; Biopsy; Blood Glucose; Cat Diseases; Cats; Diabetes Mellitus, Type 1; Exocrine Pancreatic Insufficiency; Glucagon; Immunoglobulin G; Immunoglobulin M; Immunohistochemistry; Insulin; Islet Amyloid Polypeptide; Islets of Langerhans; Pancreas; Radioimmunoassay; Somatostatin | 1995 |
A longitudinal study of plasma insulin and glucagon in women with previous gestational diabetes.
Topics: Adult; Blood Glucose; Body Mass Index; Case-Control Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Follow-Up Studies; Glucagon; Glucose Tolerance Test; Humans; Incidence; Insulin; Longitudinal Studies; Parity; Pregnancy; Reference Values; Regression Analysis; Risk Factors; Time Factors | 1995 |
Counterregulatory hormonal responses to hypoglycemia during pregnancy.
Topics: Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Pregnancy; Pregnancy in Diabetics | 1996 |
Ontogeny and tissue distribution of human GAD expression.
Topics: Adult; Brain; Diabetes Mellitus, Type 1; Embryonic and Fetal Development; Fetus; Fluorescent Antibody Technique; Gene Expression; Gestational Age; Glucagon; Glutamate Decarboxylase; Humans; Immunohistochemistry; Insulin; Islets of Langerhans; Organ Specificity; Pancreas; Transcription, Genetic | 1996 |
Differential beta-cell response to glucose, glucagon, and arginine during progression to type I (insulin-dependent) diabetes mellitus.
Topics: Adolescent; Adult; Arginine; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged | 1996 |
Evidence of recurrent autoimmunity in human allogeneic islet transplantation.
Topics: Adult; Diabetes Mellitus, Type 1; Forearm; Glucagon; Humans; Immunohistochemistry; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Recurrence; Transplantation, Homologous | 1996 |
Renal, metabolic, and hormonal responses to proteins of different origin in normotensive, nonproteinuric type I diabetic patients.
Topics: Adult; Albuminuria; Amino Acids; Animals; Blood Glucose; Blood Pressure; Cross-Over Studies; Diabetes Mellitus, Type 1; Diet, Vegetarian; Dietary Proteins; Energy Intake; Female; Glomerular Filtration Rate; Glucagon; Growth Hormone; Hormones; Humans; Insulin-Like Growth Factor I; Male; Middle Aged; Random Allocation; Renal Circulation; Vegetables | 1995 |
Kilham rat triggers T-cell-dependent autoimmune diabetes in multiple strains of rat.
Topics: Animals; Diabetes Mellitus, Type 1; Disease Susceptibility; Female; Glucagon; Haplotypes; Humans; Immunoenzyme Techniques; Immunotherapy, Adoptive; Insulin; Islets of Langerhans; Lymphocyte Activation; Male; Parvovirus; Rats; Rats, Inbred BB; Rats, Inbred Lew; Rats, Inbred Strains; Rats, Inbred WF; Species Specificity; Spleen; T-Lymphocytes | 1996 |
Cellular immune response to diverse islet cell antigens in IDDM.
Topics: Adolescent; Adult; Animals; Autoantibodies; Autoantigens; Cell Line; Child; Child, Preschool; Diabetes Mellitus, Type 1; Follow-Up Studies; Glucagon; Glutamate Decarboxylase; Humans; Immunity, Cellular; Insulin Antibodies; Islets of Langerhans; Membrane Proteins; Middle Aged; Pancreas; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Rats; Receptor-Like Protein Tyrosine Phosphatases, Class 8; Recombinant Proteins; Reference Values; T-Lymphocytes; Time Factors | 1996 |
Metabolic effects of successful intraportal islet transplantation in insulin-dependent diabetes mellitus.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Glucagon; Glucose; Glucose Clamp Technique; Homeostasis; Humans; Infusions, Intravenous; Insulin; Islets of Langerhans Transplantation; Kidney Transplantation; Liver; Liver Transplantation; Male; Middle Aged; Uveitis | 1996 |
Evidence for a major role for glucagon in regulation of plasma glucose in conscious, nondiabetic, and alloxan-induced diabetic rabbits.
Topics: Alloxan; Animals; Antibodies, Monoclonal; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Immunization, Passive; Male; Rabbits | 1996 |
Improved counter-regulatory hormonal and symptomatic responses to hypoglycemia in patients with insulin-dependent diabetes mellitus after 3 months of less strict glycemic control.
Topics: Adult; Analysis of Variance; Autonomic Nervous System; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glycated Hemoglobin; Growth Hormone; Hormones; Humans; Hydrocortisone; Hypoglycemia; Insulin; Male; Middle Aged; Norepinephrine; Perception; Regression Analysis | 1996 |
Improved postprandial metabolic control after subcutaneous injection of a short-acting insulin analog in IDDM of short duration with residual pancreatic beta-cell function.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Drug Administration Schedule; Eating; Fatty Acids, Nonesterified; Female; Glucagon; Glycerol; Humans; Hydroxybutyrates; Hypoglycemia; Injections, Subcutaneous; Insulin; Insulin Lispro; Islets of Langerhans; Lactates; Male; Recombinant Proteins; Reference Values; Time Factors | 1995 |
Abnormal circulating pancreatic enzyme activities in more than twenty-five percent of recent-onset insulin-dependent diabetic patients: association of hyperlipasemia with high-titer islet cell antibodies. Belgian Diabetes Registry.
Topics: Adolescent; Adult; Age Factors; Amylases; Analysis of Variance; Autoantibodies; Biomarkers; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucagon; Glutamate Decarboxylase; Humans; Infant; Infant, Newborn; Insulin; Islets of Langerhans; Isoamylase; Lipase; Male; Pancreas | 1996 |
Sex differences in plasma glucose thresholds for counterregulatory hormone release and hypoglycemia symptom perception.
Topics: Adult; Blood Glucose; Cognition; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Humans; Hypoglycemia; Male; Perception; Sex Characteristics | 1996 |
Myocardial ischemia induced by glucagon.
Topics: Aged; Aortic Valve Stenosis; Diabetes Mellitus, Type 1; Gastrointestinal Agents; Glucagon; Humans; Male; Myocardial Ischemia | 1996 |
Determinants of a normal (versus impaired) oral glucose tolerance after combined pancreas-kidney transplantation in IDDM patients.
Topics: Adult; alpha-Amylases; Analysis of Variance; Biomarkers; Blood Glucose; Blood Group Incompatibility; C-Peptide; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Follow-Up Studies; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Graft Rejection; Graft Survival; Histocompatibility Testing; Humans; Immunosuppressive Agents; Insulin; Insulin Secretion; Kidney Transplantation; Male; Pancreas Transplantation; Reference Values; Regression Analysis; Time Factors | 1996 |
Long-term intensive insulin therapy in IDDM: effects on HbA1c, risk for severe and mild hypoglycaemia, status of counterregulation and awareness of hypoglycaemia.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Glycated Hemoglobin; Glycerol; Human Growth Hormone; Humans; Hydrocortisone; Hydroxybutyrates; Hypoglycemia; Insulin; Lactic Acid; Male; Norepinephrine; Pancreatic Polypeptide; Perception; Risk Factors | 1996 |
The first case of insulin-dependent diabetes mellitus with prominent spurious hyperglucagonemia due to interference of immunoglobulin G in glucagon radioimmunoassay (OAL-123) system.
Topics: Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; False Positive Reactions; Glucagon; Humans; Immunoglobulin G; Insulin; Male; Middle Aged; Radioimmunoassay | 1996 |
Results of pancreatic blood shunting into the systemic blood flow in insulin-dependent diabetics.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glycated Hemoglobin; Humans; Hydrocortisone; Insulin; Male; Middle Aged; Pancreas; Radiography; Renal Veins; Splenic Vein; Splenorenal Shunt, Surgical; Vascular Patency | 1996 |
Effects of the short-acting insulin analog [Lys(B28),Pro(B29)] on postprandial blood glucose control in IDDM.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Analysis of Variance; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Glycerol; Humans; Hydroxybutyrates; Infusions, Intravenous; Insulin; Insulin Lispro; Insulin, Isophane; Lactates; Male; Postprandial Period; Recombinant Proteins | 1996 |
Mitochondrial gene abnormalities and alpha- and beta-cell dysfunction.
Topics: Adult; Arginine; Diabetes Mellitus, Type 1; DNA, Mitochondrial; Glucagon; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Kearns-Sayre Syndrome; Male; Middle Aged; Proinsulin; Sequence Deletion | 1996 |
Frequency of insulin-dependent diabetes mellitus in Turkish adult-onset diabetic population.
Topics: Adult; Age Factors; Age of Onset; Autoantibodies; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Female; Glucagon; Humans; Incidence; Insulin Antibodies; Islets of Langerhans; Male; Medical Records; Middle Aged; Turkey | 1996 |
Soluble CD8 antigen, stimulated C-peptide and islet cell antibodies are predictors of insulin requirement in newly diagnosed patients with unclassifiable diabetes.
Topics: Adolescent; Adult; Antigens, CD; Autoantibodies; Biomarkers; Body Mass Index; C-Peptide; CD8 Antigens; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Glycated Hemoglobin; Histocompatibility Testing; HLA-DR3 Antigen; Humans; Insulin; Islets of Langerhans; Male; Predictive Value of Tests; Prospective Studies | 1996 |
Local expression of transgene encoded TNF alpha in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells.
Topics: Adoptive Transfer; Animals; Autoimmunity; Cell Movement; Diabetes Mellitus, Type 1; Female; Glucagon; Glutamate Decarboxylase; Immune Tolerance; Insulin; Islets of Langerhans; Leukocytes, Mononuclear; Lymphoid Tissue; Male; Mice; Mice, Inbred NOD; Mice, SCID; Mice, Transgenic; Pancreatitis; Peptide Fragments; Promoter Regions, Genetic; Rats; Recombinant Fusion Proteins; Sex Characteristics; Spleen; T-Lymphocytes; Tumor Necrosis Factor-alpha | 1996 |
Effect of dietary protein intake on insulin secretion and glucose metabolism in insulin-dependent diabetes mellitus.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diet Records; Dietary Proteins; Female; Glucagon; Gluconeogenesis; Glucose; Humans; Insulin; Insulin Secretion; Liver; Male | 1996 |
Time course of the defective alpha-cell response to hypoglycemia in diabetic BB rats.
Topics: Animals; Diabetes Mellitus, Type 1; Glucagon; Hypoglycemia; Insulin; Islets of Langerhans; Male; Norepinephrine; Rats; Rats, Inbred BB; Time Factors | 1996 |
Glucagon-induced plasma C-peptide response in diabetic patients. Influence of body weight and relationship to insulin requirement.
Topics: Adult; Age of Onset; Body Mass Index; Body Weight; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Insulin; Male; Obesity | 1996 |
The effect of pioglitazone on hepatic glucose uptake measured with indirect and direct methods in alloxan-induced diabetic dogs.
Topics: Animals; Biological Transport; Blood Pressure; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dogs; Glucagon; Glucose; Hypoglycemic Agents; Insulin; Insulin Resistance; Liver; Pioglitazone; Thiazoles; Thiazolidinediones | 1997 |
Incretin hormone expression in the gut of diabetic mice and rats.
Topics: Animals; Blotting, Northern; Colon; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Gastric Inhibitory Polypeptide; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Intestinal Mucosa; Intestine, Small; Intestines; Mice; Mice, Inbred NOD; Peptide Fragments; Proglucagon; Protein Precursors; Rats; Rats, Zucker; Rectum; RNA, Messenger; Tissue Distribution | 1997 |
alpha-Cell neogenesis in an animal model of IDDM.
Topics: Animals; Antimetabolites; Bromodeoxyuridine; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Glucagon; Guinea Pigs; Homeodomain Proteins; Immune Sera; Immunohistochemistry; Insulin; Male; Mice; Mice, Inbred NOD; Neuropeptide Y; Pancreatic Ducts; Rabbits; Rats; Regeneration; Trans-Activators; Tyrosine 3-Monooxygenase | 1997 |
Post-marathon paradox in IDDM: unchanged insulin sensitivity in spite of glycogen depletion.
Topics: Adult; Arteries; Blood Glucose; Creatine Kinase; Diabetes Mellitus, Type 1; Energy Metabolism; Fatty Acids, Nonesterified; Female; Forearm; Glucagon; Glucose Clamp Technique; Glycogen; Glycogen Synthase; Growth Hormone; Humans; Hydrocortisone; Insulin; Insulin Resistance; Lipid Metabolism; Male; Muscles; Myoglobin; Oxidation-Reduction; Running | 1997 |
Glucagon enhances the direct suppressive effect of insulin on hepatic glucose production in humans.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Drug Synergism; Glucagon; Glucose; Humans; Insulin; Liver; Liver Circulation; Male; Tolbutamide | 1997 |
Contribution of autonomic neuropathy to reduced plasma adrenaline responses to hypoglycemia in IDDM: evidence for a nonselective defect.
Topics: 3-Hydroxybutyric Acid; Autonomic Nervous System Diseases; Blood Glucose; Carbon Dioxide; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Epinephrine; Exercise; Fatty Acids, Nonesterified; Glucagon; Glucose; Growth Hormone; Humans; Hydrocortisone; Hydroxybutyrates; Hypoglycemia; Infusions, Intravenous; Insulin; Lactates; Norepinephrine; Oxygen; Pancreatic Polypeptide; Pulmonary Ventilation | 1997 |
Blood glucose lowering and glucagonostatic effects of glucagon-like peptide I in insulin-deprived diabetic dogs.
Topics: Alanine; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Dogs; Female; Glucagon; Glucagon-Like Peptide 1; Insulin; Male; Peptide Fragments; Protein Precursors; Urea | 1997 |
Extrapancreatic islets of Langerhans: ontogenesis and alterations in diabetic condition.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Duodenum; Glucagon; Immunohistochemistry; Insulin; Intestinal Mucosa; Islets of Langerhans; Male; Microscopy, Electron; Rats; Rats, Inbred BB; Rats, Sprague-Dawley | 1997 |
Histopathologic study of the pancreas shows a characteristic lymphocytic infiltration in Japanese patients with IDDM.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antibodies, Monoclonal; Autopsy; Diabetes Mellitus, Type 1; Female; Glucagon; Guinea Pigs; Humans; Immune Sera; Immunohistochemistry; Insulin; Japan; Lymphocytes; Macrophages; Male; Middle Aged; Pancreas; Rabbits; Reference Values | 1997 |
Abnormal myocardial kinetics of 123I-heptadecanoic acid in subjects with impaired glucose tolerance.
Topics: Adult; Analysis of Variance; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Echocardiography; Fatty Acids; Fatty Acids, Nonesterified; Glucagon; Glucose Intolerance; Heart; Humans; Iodine Radioisotopes; Male; Middle Aged; Models, Cardiovascular; Myocardium; Reference Values; Tissue Distribution; Tomography, Emission-Computed; Ventricular Function, Left | 1997 |
Analysis of the possible protective role of metallothionein in streptozotocin-induced diabetes using metallothionein-null mice.
Topics: Analysis of Variance; Animals; Blood Glucose; Crosses, Genetic; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Female; Glucagon; Insulin; Metallothionein; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Mice, Transgenic; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Zinc | 1997 |
Glucose turnover and gluconeogenesis during pregnancy in women with and without insulin-dependent diabetes mellitus.
Topics: Alanine; Carbon Isotopes; Deuterium; Diabetes Mellitus, Type 1; Estradiol; Fasting; Female; Glucagon; Gluconeogenesis; Glucose; Humans; Hydrocortisone; Insulin; Liver; Placental Lactogen; Pregnancy; Pregnancy in Diabetics; Progesterone; Prolactin; Prospective Studies | 1997 |
Long-term intensive therapy of IDDM patients with clinically overt autonomic neuropathy: effects on hypoglycemia awareness and counterregulation.
Topics: Adult; Autonomic Nervous System Diseases; Blood Glucose; Cohort Studies; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Clamp Technique; Human Growth Hormone; Humans; Hydrocortisone; Hydroxybutyrates; Hypoglycemia; Hypoglycemic Agents; Insulin; Lactic Acid; Male; Middle Aged; Norepinephrine; Pancreatic Polypeptide; Perception; Time Factors | 1997 |
Studies on the mass action effect of glucose in NIDDM and IDDM: evidence for glucose resistance.
Topics: Adult; Analysis of Variance; Blood Glucose; Calorimetry, Indirect; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glucose Clamp Technique; Glycated Hemoglobin; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Reference Values; Regression Analysis; Somatostatin | 1997 |
Ontogenic changes in proglucagon mRNA in BB diabetes prone and normal rats weaned onto a chow diet.
Topics: Age Factors; Animals; Blood Glucose; Colon; Diabetes Mellitus, Type 1; Diet; Female; Gene Expression Regulation, Developmental; Glucagon; Glucagon-Like Peptide 1; Glucose Transporter Type 1; Glucose Transporter Type 2; Intestine, Small; Male; Membrane Glycoproteins; Monosaccharide Transport Proteins; Peptide Fragments; Proglucagon; Protein Precursors; Rats; Rats, Inbred BB; RNA, Messenger; Sodium-Glucose Transporter 1 | 1997 |
Lack of pharmacological effect of subcutaneous octreotide in an insulin-dependent diabetic patient: reversal after mixing with aprotinin.
Topics: Aprotinin; Blood Glucose; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Glucagon; Hormones; Human Growth Hormone; Humans; Injections, Subcutaneous; Male; Middle Aged; Octreotide; Protease Inhibitors | 1997 |
Diabetes mellitus update.
Topics: Blood Glucose; Dentists; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Epinephrine; Glucagon; Human Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Hypoglycemia; Insulin; Mouth Diseases; Patient Care Team; Terminology as Topic | 1997 |
Prediction of glucose tolerance with glucagon stimulation in pancreas transplanted patients.
Topics: Adult; Analysis of Variance; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Kidney Failure, Chronic; Kidney Transplantation; Pancreas Transplantation | 1997 |
Effects of ketamine sedation on glucose clearance, insulin secretion and counterregulatory hormone production in baboons (Papio hamadryas).
Topics: Anesthetics, Dissociative; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucagon; Glucose; Glucose Tolerance Test; Hydrocortisone; Insulin; Ketamine; Male; Papio | 1997 |
Increased epinephrine-induced cAMP response in severely diabetic BB/W rat liver.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Glucose; Cohort Studies; Corticosterone; Cyclic AMP; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Glucose; Insulin; Liver; Male; Pancreas; Perfusion; Rats; Rats, Inbred BB; Rats, Wistar; Thyroxine; Time Factors | 1997 |
Hypoglycaemia unawareness in a young boy with insulin-dependent diabetes mellitus and anti-adrenal medullary antibodies.
Topics: Adolescent; Adrenal Medulla; Age of Onset; Autoantibodies; Awareness; Blood Pressure; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Hand Strength; Heart Rate; Humans; Hypoglycemia; Insulin; Male; Norepinephrine; Perception; Posture; Seizures; Valsalva Maneuver | 1997 |
Pancreatic glucagon damages isolated human islet function.
Topics: Cells, Cultured; Diabetes Mellitus, Type 1; Gastrointestinal Agents; Glucagon; Graft Survival; Humans; Islets of Langerhans; Islets of Langerhans Transplantation | 1998 |
Proglucagon and glucose transporter mRNA is altered by diet and disease susceptibility in 30-day-old biobreeding (BB) diabetes-prone and normal rats.
Topics: Animals; Caseins; Colon; Diabetes Mellitus, Type 1; Dietary Proteins; Disease Susceptibility; Female; Glucagon; Glucose Transporter Type 5; Glycine max; Intestine, Small; Male; Monosaccharide Transport Proteins; Organ Size; Proglucagon; Protein Precursors; Rats; Rats, Inbred BB; RNA, Messenger; Stomach | 1998 |
Abrogation of autoimmune diabetes in nonobese diabetic mice and protection against effector lymphocytes by transgenic paracrine TGF-beta1.
Topics: Adoptive Transfer; Animals; Autoimmune Diseases; Clone Cells; Cyclophosphamide; Diabetes Mellitus, Type 1; Enzyme-Linked Immunosorbent Assay; Female; Genes, Synthetic; Glucagon; Islets of Langerhans; Male; Mice; Mice, Inbred NOD; Mice, Transgenic; Mutagenesis, Site-Directed; Organ Specificity; Polymerase Chain Reaction; Promoter Regions, Genetic; Rats; Recombinant Fusion Proteins; RNA, Messenger; Spleen; Swine; T-Lymphocyte Subsets; T-Lymphocytes; T-Lymphocytes, Cytotoxic; Th1 Cells; Transforming Growth Factor beta | 1998 |
Effect of residual endogenous insulin secretion on the abnormal oxytocin response to hypoglycaemia in insulin-dependent diabetics.
Topics: Adult; Blood Glucose; C-Peptide; Case-Control Studies; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Injections, Intravenous; Insulin; Insulin Secretion; Male; Oxytocin | 1998 |
Improved glucose counterregulation and autonomic symptoms after intraportal islet transplants alone in patients with long-standing type I diabetes mellitus.
Topics: Adult; Autonomic Nervous System; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Insulin; Islets of Langerhans Transplantation; Male | 1998 |
Effect of glycemic control on glucose counterregulation during hypoglycemia in NIDDM.
Topics: Adrenocorticotropic Hormone; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Epinephrine; Female; Glucagon; Glycated Hemoglobin; Homeostasis; Hormones; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Male; Middle Aged; Norepinephrine; Reference Values; Regression Analysis; Time Factors | 1998 |
Blood-to-brain glucose transport and cerebral glucose metabolism are not reduced in poorly controlled type 1 diabetes.
Topics: Adult; Blood Glucose; Blood Pressure; Blood-Brain Barrier; Carbon Radioisotopes; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glucose Clamp Technique; Glycated Hemoglobin; Heart Rate; Human Growth Hormone; Humans; Hydrocortisone; Insulin; Male; Norepinephrine; Pancreatic Polypeptide; Reference Values; Tomography, Emission-Computed | 1998 |
Integral rein control in physiology.
Topics: Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Homeostasis; Humans; Insulin; Islets of Langerhans; Models, Biological | 1998 |
Role of hyperglucagonemia in catabolism associated with type 1 diabetes: effects on leucine metabolism and the resting metabolic rate.
Topics: Adult; Amino Acids; Basal Metabolism; Calorimetry, Indirect; Diabetes Mellitus, Type 1; Energy Metabolism; Female; Glucagon; Humans; Insulin; Kinetics; Leucine; Male; Oxidation-Reduction; Proteins; Regression Analysis; Somatostatin | 1998 |
Effects of autonomic neuropathy on counterregulation and awareness of hypoglycemia in type 1 diabetic patients.
Topics: Adult; Autonomic Nervous System Diseases; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Humans; Hydrocortisone; Hypoglycemia; Insulin; Male; Norepinephrine; Perception | 1998 |
Effects of glucagon on glycogenolysis and gluconeogenesis are region-specific in periportal and perivenous hepatocytes.
Topics: Animals; Binding Sites; Calcium; Cell Separation; Cyclic AMP; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Fasting; Glucagon; Gluconeogenesis; Glucose; In Vitro Techniques; Liver; Liver Circulation; Liver Glycogen; Male; Portal Vein; Rats; Rats, Inbred BB; Rats, Wistar | 1998 |
Monitoring human islet allografts using a forearm biopsy site.
Topics: Animals; Biopsy, Needle; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Forearm; Glucagon; Humans; Insulin; Islets of Langerhans Transplantation; Lymphocytes; Mice; Mice, SCID; Monitoring, Physiologic; Transplantation, Heterotopic; Transplantation, Homologous | 1997 |
Increased splanchnic blood flow after hypoglycaemia in diabetic and normal man: evidence against glucagon as a mediator.
Topics: Adult; Case-Control Studies; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Insulin; Male; Mesenteric Artery, Superior; Regional Blood Flow; Splanchnic Circulation; Ultrasonography, Doppler, Duplex | 1999 |
Glucagon-like peptide-1 has no insulin-like effects in insulin-dependent diabetic dogs maintained normoglycemic and normoinsulinemic.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 1; Dogs; Female; Glucagon; Glucagon-Like Peptide 1; Insulin; Male; Peptide Fragments; Protein Precursors | 1999 |
Chronic hypoglycemia and diabetes impair counterregulation induced by localized 2-deoxy-glucose perfusion of the ventromedial hypothalamus in rats.
Topics: Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Homeostasis; Hypoglycemia; Male; Microdialysis; Norepinephrine; Perfusion; Rats; Rats, Inbred BB; Ventromedial Hypothalamic Nucleus | 1999 |
Mice transgenic for an expanded CAG repeat in the Huntington's disease gene develop diabetes.
Topics: Aging; Animals; Blood Glucose; Crosses, Genetic; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Huntingtin Protein; Huntington Disease; Immunohistochemistry; Insulin; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Nerve Tissue Proteins; Nuclear Proteins; Polyuria; Time Factors; Trinucleotide Repeats | 1999 |
Euglycaemic hyperinsulinaemia does not affect gastric emptying in type I and type II diabetes mellitus.
Topics: Adult; Amyloid; Blood Glucose; C-Peptide; Cholecystokinin; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glucose Clamp Technique; Glycated Hemoglobin; Humans; Hyperinsulinism; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Islet Amyloid Polypeptide; Male; Peptide Fragments; Protein Precursors | 1999 |
Hypoglycemia associated with maprotiline in a patient with type 1 diabetes.
Topics: Adult; Antidepressive Agents, Second-Generation; Blood Glucose; C-Peptide; Depressive Disorder; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Maprotiline | 1999 |
Three new mutations in the hepatocyte nuclear factor-1alpha gene in Japanese subjects with diabetes mellitus: clinical features and functional characterization.
Topics: Adult; Arginine; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; DNA; DNA-Binding Proteins; Female; Glucagon; Glucose Tolerance Test; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Mutation; Nuclear Proteins; Promoter Regions, Genetic; Transcription Factors | 1999 |
Counterregulation during spontaneous nocturnal hypoglycemia in prepubertal children with type 1 diabetes.
Topics: Blood Glucose; Child; Child, Preschool; Circadian Rhythm; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Glycated Hemoglobin; Hormones; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Hypoglycemic Agents; Insulin; Ketone Bodies; Norepinephrine; Pancreatic Polypeptide; Puberty; Reference Values | 1999 |
Lack of acute zinc effects in glucose metabolism in healthy and insulin-dependent diabetes mellitus patients.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Humans; Hydrocortisone; Male; Zinc | 1999 |
Insulin resistance in HIV protease inhibitor-associated diabetes.
Topics: Adult; Animals; Anti-HIV Agents; C-Peptide; Cells, Cultured; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Glucagon; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Insulin; Insulin Resistance; Islets of Langerhans; Male; Phospholipases A; Proinsulin; Rats; Rats, Sprague-Dawley | 1999 |
Metabolic and hormonal responses to exercise in type 1 diabetic patients during continuous subcutaneous, as compared to continuous intraperitoneal, insulin infusion.
Topics: Adult; Blood Glucose; Blood Pressure; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Equipment Design; Exercise; Female; Glucagon; Glycated Hemoglobin; Human Growth Hormone; Humans; Hydrocortisone; Insulin Infusion Systems; Male; Middle Aged; Norepinephrine; Pulse | 1999 |
Fetal pancreatic function in infants of diabetic and rhesus-isoimmunized women.
Topics: Adult; Amniotic Fluid; Arginine; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Humans; Infusions, Intravenous; Insulin; Pancreas; Pregnancy; Pregnancy in Diabetics; Rh Isoimmunization | 2000 |
Insufficient adaptation of hypoglycaemic threshold for cognitive impairment in tightly controlled type 1 diabetes.
Topics: Adult; Awareness; Blood Glucose; Cognition; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glycated Hemoglobin; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Middle Aged; Norepinephrine | 2000 |
[Comparison of hypoglycemia perception and hormonal counterregulation in controlled hypoglycemia. A contribution to diagnosis of hypoglycemia unawareness syndrome in type 1 diabetic patients].
Topics: Adult; Arousal; Awareness; Cohort Studies; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Glycated Hemoglobin; Homeostasis; Humans; Hypoglycemia; Male; Middle Aged; Patient Education as Topic; Sick Role | 2000 |
[Acute metabolic complications of diabetes mellitus (ketoacidosis, hypoglycemia, hyperosmolarity, lactic acidosis). Etiology, physiopathology, diagnosis, emergency treatment of ketoacidosis with drug posology].
Topics: Acidosis, Lactic; Aged; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Ketoacidosis; Diagnosis, Differential; Emergencies; Glucagon; Humans; Hyperglycemic Hyperosmolar Nonketotic Coma; Hypoglycemia; Insulin; Models, Biological | 2000 |
Human islet transplantation: lessons from 13 autologous and 13 allogeneic transplantations.
Topics: Autoimmunity; Biopsy; C-Peptide; Diabetes Mellitus, Type 1; Glucagon; Graft Rejection; Graft Survival; Humans; Islets of Langerhans Transplantation; Liver; Pancreatectomy; Transplantation, Autologous; Transplantation, Homologous | 2000 |
Young Chinese adults with new onset of diabetic ketoacidosis--clinical course, autoimmune status and progression of pancreatic beta-cell function.
Topics: Adult; Asian People; Autoantibodies; Blood Glucose; C-Peptide; China; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Female; Follow-Up Studies; Glucagon; Glutamate Decarboxylase; Hong Kong; Humans; Islets of Langerhans; Male | 2000 |
Function of pancreatic islets isolated from a type 1 diabetic patient.
Topics: Accidents, Traffic; Adolescent; Diabetes Mellitus, Type 1; Fatal Outcome; Female; Glucagon; Glucose; Humans; Islets of Langerhans | 2000 |
Biogenetic glucagon: new preparation. Four times more expensive for the same service.
Topics: Adrenergic beta-Antagonists; Animals; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Drug Costs; Glucagon; Humans; Hypoglycemia; Treatment Outcome | 1998 |
Temporal relationship between immune cell influx and the expression of inducible nitric oxide synthase, interleukin-4 and interferon-gamma in pancreatic islets of NOD mice following adoptive transfer of diabetic spleen cells.
Topics: Adoptive Transfer; Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Transplantation; Diabetes Mellitus, Type 1; Glucagon; Guinea Pigs; Immunohistochemistry; Incidence; Insulin; Interferon-gamma; Interleukin-4; Islets of Langerhans; Lymphocyte Count; Macrophages; Mice; Mice, Inbred NOD; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rabbits; Rats; Sheep; Somatostatin; Spleen | 2000 |
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Glucose or glucagon for hypoglycaemia.
Topics: Adult; Diabetes Mellitus, Type 1; Evidence-Based Medicine; Glucagon; Glucose; Humans; Hypoglycemia; MEDLINE | 2000 |
Impairment and recovery of elementary cognitive function induced by hypoglycemia in type-1 diabetic patients and healthy controls.
Topics: Adrenocorticotropic Hormone; Adult; Cognition; Cognition Disorders; Diabetes Mellitus, Type 1; Epinephrine; Evoked Potentials; Female; Glucagon; Glucose Clamp Technique; Humans; Hydrocortisone; Hyperinsulinism; Hypoglycemia; Infusions, Intravenous; Insulin; Male; Norepinephrine; Reaction Time; Reference Values | 2000 |
Functional rest through intensive treatment with insulin and potassium channel openers preserves residual beta-cell function and mass in acutely diabetic BB rats.
Topics: Animals; Arginine; Blood Glucose; C-Peptide; Cells, Cultured; Diabetes Mellitus, Type 1; Diazoxide; Glucagon; Glucose Tolerance Test; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Potassium Channels; Rats; Rats, Inbred BB; Rats, Inbred WF | 2000 |
Intractable hypoglycemia in a patient with diabetes mellitus, bilateral nephrectomy, and chronic active hepatitis.
Topics: Adolescent; Diabetes Mellitus, Type 1; Diagnosis, Differential; Female; Glucagon; Hepatitis B, Chronic; Humans; Hyperinsulinism; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Kidney Failure, Chronic; Nephrectomy; Protein Synthesis Inhibitors; Substance Abuse, Intravenous; Treatment Outcome; Uremia | 2000 |
Diabetogenic role of insulin's counterregulatory hormones in the isletectomized, diabetic goby.
Topics: Ammonia; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Fishes; Glucagon; Hydrocortisone; Hyperglycemia; Insulin; Islets of Langerhans; Kinetics; Nitrogen; Rats | 2000 |
Effect of glucagon-like peptide-1(7-36)-amide on initial splanchnic glucose uptake and insulin action in humans with type 1 diabetes.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Duodenum; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Human Growth Hormone; Hydrocortisone; Hypoglycemic Agents; Insulin; Intubation; Osmolar Concentration; Peptide Fragments; Viscera | 2001 |
IL-12 plays a pathologic role at the inflammatory loci in the development of diabetes in NOD mice.
Topics: Animals; Cyclophosphamide; Diabetes Mellitus, Type 1; Dimerization; Female; Gene Expression; Glucagon; Immunosuppressive Agents; Incidence; Interleukin-12; Islets of Langerhans; Mice; Mice, Inbred NOD; Mice, Transgenic; Promoter Regions, Genetic | 2001 |
Effects of short-term improvement of insulin treatment and glycemia on hepatic glycogen metabolism in type 1 diabetes.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Glycogen; Humans; Hypoglycemic Agents; Insulin; Liver; Male; Time Factors | 2001 |
Hepatic insulin expression improves glycemic control in type 1 diabetic rats.
Topics: Amino Acid Sequence; Animals; Blood Glucose; Consensus Sequence; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Furin; Gene Transfer Techniques; Genetic Therapy; Glucagon; Hyperglycemia; Insulin; Islets of Langerhans; Liver; Liver Neoplasms, Experimental; Proinsulin; Protein Precursors; Rats; Rats, Nude; Subtilisins; Transfection | 2001 |
Renal handling of zinc in insulin-dependent diabetes mellitus patients.
Topics: Adult; Blood Glucose; C-Peptide; Case-Control Studies; Creatinine; Diabetes Mellitus, Type 1; Female; Glomerular Filtration Rate; Glucagon; Glycosuria; Humans; Hydrocortisone; Kidney; Kidney Tubules; Male; Zinc | 2001 |
No influence of C-peptide, insulin, and glucagon on blood viscosity in vitro in healthy humans and patients with diabetes mellitus.
Topics: Adult; Aged; Blood Proteins; Blood Viscosity; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Dose-Response Relationship, Drug; Erythrocyte Indices; Female; Glucagon; Glycated Hemoglobin; Humans; Insulin; Male; Middle Aged | 2001 |
High levels of antigen-specific islet antibodies predict future beta-cell failure in patients with onset of diabetes in adult age.
Topics: Adult; Aged; Autoantibodies; C-Peptide; Diabetes Mellitus, Type 1; Fasting; Female; Glucagon; Glucose Tolerance Test; Glutamate Decarboxylase; Glycated Hemoglobin; Humans; Islets of Langerhans; Kinetics; Male; Membrane Proteins; Middle Aged; Nerve Tissue Proteins; Prospective Studies; Receptor-Like Protein Tyrosine Phosphatases, Class 8; ROC Curve; Sensitivity and Specificity | 2001 |
Neonatal treatment with beta-cell stimulatory agents reduces the incidence of diabetes in BB rats.
Topics: Animals; Animals, Newborn; Arginine; Diabetes Mellitus, Type 1; Drug Combinations; Female; Glucagon; Glucose; Incidence; Islets of Langerhans; Male; Protamines; Rats; Rats, Inbred BB; Theophylline; Time Factors; Tolbutamide | 2000 |
Islet endocrine-cell behavior from birth onward in mice with the nonobese diabetic genetic background.
Topics: Aging; Animals; Blood Glucose; Corticosterone; Diabetes Mellitus, Type 1; Female; Glucagon; Immunohistochemistry; Insulin; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, SCID; Radioimmunoassay; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Weaning | 2001 |
Influence of age on clinical and immunological characteristics of newly diagnosed type 1 diabetic patients.
Topics: Adult; Aging; Autoantibodies; C-Peptide; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucagon; Glutamate Decarboxylase; Glycated Hemoglobin; Humans; Islets of Langerhans; Male; Pancreas; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases | 2001 |
Skeletal muscle glucose uptake, glycogen synthase activity and GLUT 4 content during hypoglycaemia in type 1 diabetic subjects.
Topics: Adult; Biopsy; Blood Glucose; Calorimetry, Indirect; Diabetes Mellitus, Type 1; Epinephrine; Forearm; Glucagon; Gluconeogenesis; Glucose; Glucose Clamp Technique; Glucose Transporter Type 4; Glycogen Synthase; Human Growth Hormone; Humans; Hydrocortisone; Hyperinsulinism; Hypoglycemia; Insulin; Kinetics; Lipids; Male; Middle Aged; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal | 2001 |
Cardiac responses to insulin-induced hypoglycemia in nondiabetic and intensively treated type 1 diabetic patients.
Topics: Adult; Cardiac Output; Catecholamines; Chemical Precipitation; Diabetes Mellitus, Type 1; Diastole; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Clamp Technique; Heart; Heart Rate; Humans; Hydrocortisone; Hypoglycemia; Insulin; Lactic Acid; Male; Norepinephrine; Polyethylene Glycols; Stroke Volume; Systole; Ventricular Function, Left | 2001 |
Failure to develop diabetic ketoacidosis in a newly presenting type 1 diabetic patient.
Topics: Addison Disease; Adolescent; C-Peptide; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Female; Glucagon; Humans; Triglycerides | 2001 |
The effect of evening alcohol consumption on next-morning glucose control in type 1 diabetes.
Topics: Adult; Alcohol Drinking; Area Under Curve; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Glucagon; Human Growth Hormone; Humans; Hydrocortisone; Insulin; Male; Middle Aged; Wine | 2001 |
Insulin independence and normalization of oral glucose tolerance test after islet cell allotransplantation.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Follow-Up Studies; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Islets of Langerhans Transplantation; Reference Values; Time Factors; Transplantation, Homologous | 2001 |
Insulin infusion normalizes fasting and post-prandial albumin and fibrinogen synthesis in Type 1 diabetes mellitus.
Topics: Adult; Amino Acids; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 1; Fasting; Female; Fibrinogen; Food; Glucagon; Humans; Infusions, Intravenous; Insulin; Kinetics; Male; Phenylalanine; Serum Albumin; Tritium | 2001 |
Effect of GLP-1 treatment on GLUT2 and GLUT4 expression in type 1 and type 2 rat diabetic models.
Topics: Adipose Tissue; Animals; Blotting, Northern; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Transporter Type 2; Glucose Transporter Type 4; Liver; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Peptide Fragments; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger | 2001 |
Is the process of beta-cell destruction in type 1 diabetes at time of diagnosis more extensive in females than in males?
Topics: Adolescent; Adult; Body Mass Index; C-Peptide; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Glycated Hemoglobin; Humans; Insulin; Islets of Langerhans; Male; Puberty; Sex Characteristics | 2001 |
GLP-1 effect upon the GPI/IPG system in adipocytes and hepatocytes from diabetic rats.
Topics: Adipocytes; Animals; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 1; Glycosylphosphatidylinositols; Hepatocytes; Hypoglycemic Agents; Inositol Phosphates; Insulin; Liver; Male; Oligosaccharides; Pancreas; Peptide Fragments; Polysaccharides; Protein Precursors; Rats; Rats, Wistar | 2001 |
Basal and postglucagon C-peptide levels in Ethiopians with diabetes.
Topics: Adult; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Ethiopia; Female; Glucagon; Humans; Insulin; Male; Reference Values; Socioeconomic Factors | 2002 |
Induction and acceleration of insulitis/diabetes in mice with a viral mimic (polyinosinic-polycytidylic acid) and an insulin self-peptide.
Topics: Alleles; Animals; CD4 Antigens; CD4-Positive T-Lymphocytes; CD8 Antigens; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Genotype; Glucagon; Immunohistochemistry; Insulin; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Peptides; Poly I-C; Time Factors | 2002 |
Beta cell expression of IGF-I leads to recovery from type 1 diabetes.
Topics: Animals; Apoptosis; Blood Glucose; Body Weight; Cell Division; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drinking; Eating; Glucagon; Humans; Insulin; Insulin-Like Growth Factor I; Islets of Langerhans; Mice; Mice, Inbred C57BL; Mice, Transgenic | 2002 |
Glycemic response during exercise after administration of insulin lispro compared with that after administration of regular human insulin.
Topics: Adult; Analysis of Variance; Anti-Bacterial Agents; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Epinephrine; Exercise; Glucagon; Human Growth Hormone; Humans; Insulin; Insulin Lispro; Kinetics; Norepinephrine | 2002 |
Transient neonatal diabetes mellitus, type 4, type 1 diabetes mellitus, or MODY: which disease is it, anyway?
Topics: Adult; Arginine; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucose Tolerance Test; Humans; Infant; Insulin; Insulin Secretion; Islets of Langerhans; Male; Tolbutamide | 2002 |
Failure of somatostatin to correct manifest diabetic ketoacidosis.
Topics: Adult; Blood Glucose; Cyclic AMP; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Drug Evaluation; Fatty Acids, Nonesterified; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Infusions, Parenteral; Insulin; Ketone Bodies; Male; Somatostatin | 1976 |
Insulin resistance caused by massive degradation of subcutaneous insulin.
Topics: Adipose Tissue; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Ethylmaleimide; Female; Glucagon; Humans; Infusions, Parenteral; Injections, Intravenous; Injections, Subcutaneous; Insulin; Insulin Resistance | 1979 |
[Infantile diabetes mellitus. Metabolic problems and therapeutic prospects].
Topics: Blood Coagulation Disorders; C-Peptide; Child; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Ketoacidosis; Diabetic Retinopathy; Glucagon; Hemoglobin A; Humans; Insulin; Insulin Secretion | 1979 |
Hypertrophy and hyperplasia of somatostatin-containing D-cells in diabetes.
Topics: Adult; Animals; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hyperplasia; Hypertrophy; Insulin; Islets of Langerhans; Male; Rats; Somatostatin; Streptozocin | 1976 |
Monozygotic triplets with discordance for diabetes mellitus and diabetic microangiopathy.
Topics: Adolescent; Adult; Antigens; Basement Membrane; Blood Glucose; Capillaries; Cortisone; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Female; Glucagon; Glucose Tolerance Test; Herpesvirus 4, Human; Histocompatibility Antigens; Humans; Infusions, Parenteral; Insulin; Male; Phenotype; Pregnancy; Tolbutamide; Triplets | 1977 |
The nature of the endocrine system. Part 5; the pancreas gland.
Topics: Adenoma, Islet Cell; Adult; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Coma; Glucagon; Humans; Hypoglycemia; Pancreatic Diseases; Pancreatic Hormones; Pancreatic Neoplasms | 1977 |
Plasma cyclic nucleotide levels in juvenile-onset diabetes.
Topics: Adult; Blood Glucose; Cyclic AMP; Cyclic GMP; Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Insulin; Male | 1977 |
Congenital generalized lipodystrophy with insulin-resistant diabetes.
Topics: Acanthosis Nigricans; Arginine; Child; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glucagon; Humans; Insulin Resistance; Leukocytes; Lipodystrophy; Lipoproteins, LDL; Male; Receptor, Insulin; Sulfonylurea Compounds; Triglycerides | 1978 |
[Glucagon, ACTH and cortisol content in the blood in diabetes mellitus in children].
Topics: Adolescent; Adrenocorticotropic Hormone; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Glucagon; Humans; Hydrocortisone | 1979 |
The development and regulation of the endocrine pancreas.
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; Humans; Infant, Newborn; Infant, Newborn, Diseases; Insulin; Insulin Secretion; Islets of Langerhans; Somatostatin | 1977 |
Incidence and significance of islet-cell autoantibodies in different types of diabetes mellitus.
Topics: Adult; Aged; Autoantibodies; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Fluorescent Antibody Technique; Glucagon; Humans; Insulin; Islets of Langerhans; Male; Middle Aged | 1977 |
[Various disturbances in beta cell function in diabetes mellitus].
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Humans; Insulin; Islets of Langerhans; Middle Aged; Receptors, Drug; Tolbutamide | 1977 |
Autoimmunity and the endocrine pancreas.
Topics: Antibodies; Autoantibodies; Autoimmune Diseases; Cytotoxicity, Immunologic; Diabetes Mellitus; Diabetes Mellitus, Type 1; Fluorescent Antibody Technique; Glucagon; HLA Antigens; Humans; Immunity, Cellular; Insulin; Islets of Langerhans; Lymphocytes; Pancreas; Receptor, Insulin; Somatostatin | 1977 |
The effect of residual insulin secretion on exocrine pancreatic function in juvenile-onset diabetes mellitus.
Topics: Adolescent; Adult; Amylases; Bicarbonates; C-Peptide; Cholecystokinin; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Pancreas; Secretin; Trypsin | 1978 |
Abnormal alpha cell function in human diabetes: the response to oral protein.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Dietary Proteins; Fasting; Female; Glucagon; Humans; Hyperglycemia; Hyperinsulinism; Infusions, Parenteral; Insulin; Islets of Langerhans; Male; Middle Aged | 1978 |
Islet cell antibodies and diabetes mellitus in Pima Indians.
Topics: Adolescent; Adult; Arizona; Autoantibodies; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Indians, North American; Islets of Langerhans; Male; Middle Aged | 1979 |
D-Trp8-D-Cys14-somatostatin--demonstration of its differential suppressive activity in juvenile diabetics.
Topics: Adolescent; Adult; Artificial Organs; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Growth Hormone; Humans; Infusions, Parenteral; Insulin; Islets of Langerhans; Somatostatin | 1979 |
The external artificial pancreas: an instrument to induce remissions in severe recent juvenile diabetes. Comparison with a preprogrammed insulin infusion system.
Topics: Acute Disease; Adult; Artificial Organs; Blood Glucose; Diabetes Mellitus, Type 1; Eating; Feedback; Glucagon; Humans; Infusions, Parenteral; Insulin; Islets of Langerhans; Remission, Spontaneous | 1979 |
The effect of three days of blood glucose normalization by means of an "artificial endocrine pancreas" on the concentrations of growth hormone, glucagon, and cortisol in juvenile diabetics.
Topics: Adult; Artificial Organs; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Feedback; Glucagon; Growth Hormone; Humans; Hydrocortisone; Infusions, Parenteral; Insulin; Islets of Langerhans; Middle Aged | 1979 |
Hyperglycemia inhibits glucose production in man independent of changes in glucoregulatory hormones.
Topics: Adult; Blood Glucose; Catecholamines; Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Insulin; Liver | 1978 |
Role of glucagon in diabetes.
Topics: Antigens; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Extracellular Space; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Islets of Langerhans; Models, Biological | 1977 |
Ketoacidosis in pancreatectomized man.
Topics: Acetoacetates; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Female; Glucagon; Gluconeogenesis; Humans; Hydroxybutyrates; Insulin; Male; Middle Aged; Pancreatectomy | 1977 |
[New thoughts on diabetes mellitus (author's transl)].
Topics: Animals; Autoimmune Diseases; Circadian Rhythm; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Glucagon; Glucose; Humans; Insulin; Pancreas; Receptor, Insulin; Virus Diseases | 1977 |
The care of the diabetic child in general practice.
Topics: Adipose Tissue; Adolescent; Atrophy; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Dietary Carbohydrates; Family Practice; Glucagon; Glycosuria; Humans; Hypoglycemia; Insulin; Ketones; Vomiting | 1977 |
Effects of exogenous hyperglucagonemia in insulin-treated diabetics.
Topics: Adult; Antigens; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Female; Glucagon; Glycosuria; Humans; Insulin; Ketones; Middle Aged; Nitrogen; Urea | 1977 |
Metabolic and hormonal effects of muscular exercise in juvenile type diabetics.
Topics: Adolescent; Adult; Amino Acids; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Fatty Acids, Nonesterified; Glucagon; Growth Hormone; Humans; Hydrocortisone; Insulin; Ketone Bodies; Kinetics; Lipids; Male; Physical Exertion | 1977 |
Glucagon and growth hormone secretion in insulin-treated diabetics: effects of added sulfonylureas.
Topics: Adult; Arginine; Diabetes Mellitus, Type 1; Female; Glucagon; Glyburide; Growth Hormone; Humans; Insulin; Male; Middle Aged | 1978 |
Circulating glucagon antibodies in children who have insulin-dependent diabetes mellitus. Clinical significance and characterization.
Topics: Adolescent; Antibodies; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Growth Hormone; Humans; Insulin; Thyroxine | 1979 |
Influence of continuous physiologic hyperinsulinemia on glucose kinetics and counterregulatory hormones in normal and diabetic humans.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Growth Hormone; Humans; Hydrocortisone; Infusions, Parenteral; Insulin; Male; Norepinephrine | 1979 |
Effects of insulin on the response of immunoreactive glucagon to an intravenous glucose load in human diabetes.
Topics: Adult; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Humans; Infusions, Parenteral; Insulin; Male; Middle Aged | 1979 |
Changes in glucagon levels after four to five weeks of glucoregulation by portable insulin infusion pumps.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Infusions, Parenteral; Insulin; Male | 1979 |
Normalisation of growth hormone hypersecretion in uraemic diabetics and non-diabetics. Studies with artificial pancreas and artificial kidney.
Topics: Alanine; Artificial Organs; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Glycerol; Growth Hormone; Humans; Hydroxybutyrates; Kidneys, Artificial; Lactates; Male; Pancreas; Renal Dialysis; Uremia | 1979 |
[Glucagon response to a high protein meal in normal and diabetic subjects (author's transl)].
Topics: Adult; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Dietary Proteins; Fasting; Female; Glucagon; Humans; Male; Middle Aged; Radioimmunoassay | 1978 |
C-peptide in diabetic children after stimulation with clucagon compared with fasting C-peptide levels in non-diabetic children.
Topics: Adolescent; Adult; C-Peptide; Child; Diabetes Mellitus, Type 1; Fasting; Female; Glucagon; Humans; Injections, Intravenous; Insulin; Male; Peptides | 1977 |
The effect of short-term intravenous insulin administration on the glucagon response to a carbohydrate meal in adult onset and juvenile type diabetes.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Dietary Carbohydrates; Female; Glucagon; Glucose; Humans; Insulin; Kinetics; Male; Middle Aged | 1977 |
Differential effects of L-dopa and apomorphine on glucagon secretion in man: evidence against central dopaminergic stimulation of glucagon.
Topics: Adult; Apomorphine; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; Humans; Insulin; Levodopa; Male; Prolactin; Receptors, Dopamine | 1977 |
24-hour studies of the effects of somatostatin on the levels of plasma growth hormone, glucagon, and glucose in normal subjects and juvenile diabetics.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Growth Hormone; Humans; Kinetics; Male; Somatostatin | 1978 |
Effect of insulin therapy on the profiles of plasma immunoreactive glucagon in juvenile-type and adult-type diabetics.
Topics: Adult; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Insulin; Male; Middle Aged; Time Factors | 1978 |
The effect of hyperglucagonemia on blood glucose concentrations and on insulin requirements in insulin-requiring diabetes mellitus.
Topics: Adult; Artificial Organs; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Female; Glucagon; Humans; Insulin; Male; Middle Aged | 1978 |
Pathophysiology of diabetes mellitus.
Topics: Amino Acids; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Dietary Carbohydrates; Glucagon; Homeostasis; Humans; Insulin; Insulin Resistance; Insulin Secretion; Lipid Metabolism; Somatostatin | 1978 |
Twenty-four-hour somatostatin infusions in normals, juvenile diabetics, and maturity-onset diabetics.
Topics: Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; Growth Hormone; Humans; Insulin; Male; Somatostatin; Time Factors | 1978 |
[Changes of insulin antagonists in juvenile diabetes mellitus--with special reference to growth hormone and glucagon].
Topics: Child; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; Humans; Insulin Antagonists; Male; Radioimmunoassay | 1978 |
Glucagon's importance for diabetic patients is shown in study.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans | 1979 |
[Glucagon and diabetes].
Topics: Adolescent; Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Dogs; Glucagon; Humans; Islets of Langerhans | 1976 |
Somatostatin--clinical implications.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Digestive System; Gastric Mucosa; Glucagon; Growth Hormone; Humans; Hyperglycemia; Insulin; Islets of Langerhans; Pancreas; Rats; Somatostatin | 1976 |
Arginine-stimulated acute phase of insulin and glucagon secretion in diabetic subjects.
Topics: Adolescent; Adult; Antigens; Arginine; Diabetes Mellitus; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Female; Glucagon; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Stimulation, Chemical | 1976 |
Current aspects of aetiology and diagnosis in diabetes mellitus.
Topics: Adult; Child; Child, Preschool; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; Glucose Tolerance Test; Histocompatibility Antigens; Humans; Hyperglycemia; Islets of Langerhans; Somatostatin; Virus Diseases | 1976 |
Prevention of human diabetic ketoacidosis by somatostatin. Evidence for an essential role of glucagon.
Topics: Adult; Alanine; Blood Glucose; Depression, Chemical; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Fatty Acids, Nonesterified; Glucagon; Glycerol; Growth Hormone; Humans; Hydrocortisone; Hydroxybutyrates; Hyperglycemia; Insulin; Ketone Bodies; Lactates; Male; Peptides; Substance Withdrawal Syndrome | 1975 |
[The historic role of insulin in the physiopathology of the metabolic complications from pancreatic diabetes. Therapeutic implications for somatostatin].
Topics: Adult; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; Humans; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Somatostatin | 1975 |
Suppressibility of glucagon secretion by glucose in juvenile diabetes.
Topics: Adolescent; Blood Glucose; Child; Depression, Chemical; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Growth Hormone; Humans; Insulin; Male | 1977 |
Plasma immunoreactive insulin response to 100g-glucose-glucagon-tolbutamide stimulation in juvenile-onset diabetics.
Topics: Adult; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Antibodies; Male; Tolbutamide | 1977 |
Glucagon and diabetes. II. Complete suppression of glucagon by insulin in human diabetes.
Topics: Adolescent; Adult; Blood Glucose; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Insulin; Male | 1977 |
Glucagon response to arginine stimulation in obese and diabetic children.
Topics: Adolescent; Arginine; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; Humans; Male; Obesity | 1977 |
Hormonal and metabolic effects of somatostatin in diabetic patients submitted to an i.v. arginine infusion.
Topics: Adult; Alanine; Arginine; Blood Glucose; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Drug Tolerance; Fatty Acids, Nonesterified; Female; Glucagon; Growth Hormone; Hemostasis; Hormones; Humans; Hydrocortisone; Hydroxybutyrates; Male; Nitrogen; Somatostatin | 1977 |
Transient diabetes mellitus in a neonate. Evaluation of insulin, glucagon, and growth hormone secretion and management with a continuous low-dose insulin infusion.
Topics: Adolescent; Antigens; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Growth Hormone; Humans; Hyperglycemia; Infant, Newborn; Infant, Newborn, Diseases; Infusions, Parenteral; Insulin; Insulin Secretion; Pregnancy; Somatostatin; Theophylline; Time Factors; Tolbutamide | 1977 |
Plasma glucagon suppression by phenformin in man.
Topics: Adult; Amines; Diabetes Mellitus, Type 1; Eating; Female; Glucagon; Humans; Insulin; Male; Middle Aged; Phenformin | 1977 |
Effects of acute insulin withdrawal and administration on plasma glucagon responses to intravenous arginine in insulin-dependent diabetic subjects.
Topics: Adolescent; Adult; Arginine; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Male | 1976 |
The effects of acute and chronic insulin administration on plasma IRG levels in human diabetes.
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Insulin | 1976 |
[Value of the method of Cerasi and Luft in checking the progression of metabolic disorders in childhood].
Topics: Blood Glucose; Child; Child, Preschool; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diet, Diabetic; Glucagon; Humans; Insulin; Insulin Secretion; Obesity | 1976 |
Antidiabetic action of somatostatin--assessed by the artificial pancreas.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Glucose Tolerance Test; Growth Hormone; Humans; Hypoglycemic Agents; Injections, Intravenous; Insulin; Islets of Langerhans; Male; Somatostatin | 1975 |
Studies on the mechanism of epinephrine-induced hyperglycemia in man. Evidence for participation of pancreatic glucagon secretion.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Drug Synergism; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Humans; Hyperglycemia; Islets of Langerhans; Male; Middle Aged; Phentolamine; Propranolol; Somatostatin | 1976 |
Letter: Transient neonatal diabetes-possible therapeutic use for glucagon.
Topics: Diabetes Mellitus, Type 1; Drug Therapy, Combination; Glucagon; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Insulin; Male | 1975 |
Plasma glucagon and alanine responses to acute insulin deficiency in man.
Topics: Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glucagon; Glycerol; Humans; Hydroxybutyrates; Insulin; Male; Time Factors | 1975 |
[Insulin secretion in obese and diabetic children evaluated with venous perfusion of glucose and stimulation with glucagon. preliminary data].
Topics: Child; Child, Preschool; Diabetes Mellitus, Type 1; Glucagon; Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Obesity; Prediabetic State | 1975 |
[Blood levels of insulin, pancreatic glucagon and growth hormone following intravenous infusion of L-arginine in patients with recently diagnosed juvenile diabetes].
Topics: Adolescent; Adult; Arginine; Child; Diabetes Mellitus, Type 1; Glucagon; Growth Hormone; Humans; Insulin; Middle Aged; Pancreas | 1975 |
The effect of somatostatin on coagulation and platelet function in man.
Topics: Adenosine Diphosphate; Adult; Blood Cell Count; Blood Coagulation; Blood Coagulation Tests; Blood Glucose; Blood Platelets; Collagen; Diabetes Mellitus, Type 1; Drug Evaluation; Epinephrine; Female; Fibrin; Fibrinogen; Glucagon; Hematocrit; Humans; Infusions, Parenteral; Leukocyte Count; Male; Platelet Adhesiveness; Platelet Aggregation; Prothrombin Time; Serotonin; Somatostatin | 1975 |
Effect of physical exercise on secretion of growth hormone, glucagon, and cortisol in obese and diabetic children.
Topics: Adolescent; Blood Glucose; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Growth Hormone; Humans; Hydrocortisone; Male; Obesity; Physical Exertion | 1975 |
Glucagon secretion in unaffected monozygotic twins of juvenile diabetics.
Topics: Adult; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Prediabetic State; Pregnancy; Twins | 1975 |
Plasma glucagon response to arginine infusion in children and adolescents with diabetes mellitus.
Topics: Adolescent; Adult; Arginine; Blood Glucose; Child; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Growth Hormone; Humans; Insulin; Male; Prediabetic State | 1975 |
Effect of adrenergic blockade on glucagon and growth hormone secretion in normal and diabetic children.
Topics: Adolescent; Arginine; Blood Glucose; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; Humans; Male; Phentolamine; Pituitary-Adrenal System; Propranolol | 1975 |
Glucose, insulin, pancreatic glucagon and glucagon-like immunoreactive materials in the plasma of normal and diabetic children. Effect of the initial insulin treatment.
Topics: Adolescent; Blood Glucose; Body Height; Body Weight; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Insulin; Insulin Antibodies; Ketone Bodies; Male | 1975 |
[Specific radioimmunoassay of pancreatic glucagon. Results in new-born and in child (author's transl)].
Topics: Animals; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Immune Sera; Mathematics; Pregnancy; Radioimmunoassay | 1975 |
Hyperglucagonemia and blood glucose regulation in normal, obese and diabetic subjects.
Topics: Adult; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucagon; Homeostasis; Humans; Infusions, Parenteral; Insulin; Male; Middle Aged; Obesity | 1976 |
Comparative HGH response to i.v. glucagon and i.v. arginine stimulation tests in children and adolescents.
Topics: Adolescent; Arginine; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Growth Disorders; Growth Hormone; Humans; Hypopituitarism; Infant; Injections, Intravenous; Male | 1976 |
[Infantile diabetes].
Topics: Adolescent; Arginine; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Male; Tolbutamide | 1976 |
Effect of insulin on the exaggerated glucagon response to arginine stimulation in diabetes mellitus.
Topics: Adolescent; Adult; Arginine; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Insulin; Male; Middle Aged | 1976 |
Effect of somatostatin on blood sugar, plasma growth hormone, and glucagon levels in diabetic children.
Topics: Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; Humans; Male; Somatostatin; Time Factors | 1976 |
The dawn phenomenon: comparison between normal and insulin-dependent diabetic adolescents.
Topics: Adolescent; Adrenocorticotropic Hormone; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Insulin; Insulin Resistance; Male | 1992 |
A Chinese woman with glucagonoma syndrome.
Topics: Adenoma, Islet Cell; Aged; Diabetes Mellitus, Type 1; Female; Glucagon; Glucagonoma; Humans; Pancreatic Neoplasms; Syndrome | 1992 |
Inhibition by salbutamol of GHRH-induced GH release in type 1 diabetes mellitus.
Topics: Adult; Albuterol; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Male; Receptors, Adrenergic, beta | 1992 |
Inhibitory effect of circulating insulin on glucagon secretion during hypoglycemia in type I diabetic patients.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Glycated Hemoglobin; Growth Hormone; Humans; Hypoglycemia; Insulin; Insulin Antibodies; Kinetics; Male; Norepinephrine; Pancreatic Polypeptide; Somatostatin | 1992 |
Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Eating; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Infusion Systems; Insulin Secretion; Male; Middle Aged; Obesity; Peptide Fragments; Peptides; Somatostatin | 1992 |
Transplantation of encapsulated canine islets into spontaneously diabetic BB/Wor rats without immunosuppression.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 1; Glucagon; Glucose Tolerance Test; Immunoenzyme Techniques; Immunosuppression Therapy; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Membranes, Artificial; Microscopy, Electron; Rats; Rats, Inbred BB; Somatostatin | 1992 |
Lack of feedback inhibition of insulin secretion in denervated human pancreas.
Topics: 3-Hydroxybutyric Acid; Adult; Analysis of Variance; Blood Glucose; C-Peptide; Denervation; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Epinephrine; Fatty Acids, Nonesterified; Feedback; Follow-Up Studies; Glucagon; Glucose Clamp Technique; Glycated Hemoglobin; Hormones; Humans; Hydroxybutyrates; Insulin; Insulin Secretion; Kidney Transplantation; Lactates; Pancreas; Pancreas Transplantation; Pancreatic Polypeptide; Somatostatin; Uremia | 1992 |
Glucagon, insulin and somatostatin secretion in response to sympathetic neural activation in streptozotocin-induced diabetic rats. A study with the isolated perfused rat pancreas in vitro.
Topics: Animals; Animals, Newborn; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Electric Stimulation; Glucagon; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Neurons; Perfusion; Rats; Rats, Wistar; Somatostatin; Splanchnic Nerves; Streptozocin; Sympathetic Nervous System | 1992 |
Demonstration of islet cell antibodies in apparently non-insulin dependent diabetic patients; a marker for the later development of insulin dependency.
Topics: Autoantibodies; Biomarkers; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Progression; Female; Glucagon; Humans; Islets of Langerhans; Male; Middle Aged; Prognosis | 1991 |
[Blood platelet as a test system in the evaluation of neurohormonal imbalance in pregnant women with diabetes mellitus].
Topics: Adrenocorticotropic Hormone; Blood Platelets; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Humans; Hydrocortisone; Metaproterenol; Pregnancy; Pregnancy in Diabetics; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Stimulation, Chemical | 1992 |
Diabetes-related autoantibodies do appear in children with coeliac disease.
Topics: Adolescent; Antibodies, Anti-Idiotypic; Autoantibodies; Celiac Disease; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Gliadin; Glucagon; HLA-DR Antigens; Humans; Immunoglobulin A; Immunoglobulin G; Infant; Insulin; Islets of Langerhans; Male; Phenotype | 1992 |
Further defects in counterregulatory responses induced by recurrent hypoglycemia in IDDM.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose; Glucose Clamp Technique; Growth Hormone; Homeostasis; Hormones; Humans; Hydrocortisone; Hypoglycemia; Insulin; Liver; Male; Norepinephrine; Time Factors | 1992 |
Impaired stimulation of gluconeogenesis during prolonged hypoglycemia in intensively treated insulin-dependent diabetic subjects.
Topics: Adult; Analysis of Variance; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Gluconeogenesis; Humans; Hypoglycemia; Insulin; Male; Time Factors | 1992 |
Advances in diabetes research.
Topics: Antidepressive Agents; Demyelinating Diseases; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Nerve Degeneration; Neuralgia; Peptides; Research | 1992 |
The dawn phenomenon and diabetes control in treated NIDDM and IDDM patients.
Topics: Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Glyburide; Glycated Hemoglobin; Growth Hormone; Humans; Hydrocortisone; Insulin; Male; Middle Aged | 1992 |
Fuel and fluid homeostasis during long-term exercise in healthy subjects and type I diabetic patients.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Electrolytes; Energy Metabolism; Exercise; Glucagon; Growth Hormone; Homeostasis; Hormones; Humans; Hydrocortisone; Insulin; Male; Reference Values; Renin; Skiing; Sports; Water-Electrolyte Balance | 1992 |
Glucagon-glucose (GG) test for the estimation of the insulin reserve in diabetes.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diet, Diabetic; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Islets of Langerhans; Middle Aged; Prediabetic State | 1992 |
Cellular and humoural autoimmunity markers in type 2 (non-insulin-dependent) diabetic patients with secondary drug failure.
Topics: Analysis of Variance; Animals; Antibody Formation; Autoantibodies; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; HLA Antigens; HLA-DQ Antigens; HLA-DR Antigens; Humans; Hypoglycemic Agents; Immunity, Cellular; Insulin; Insulin Antibodies; Insulin Secretion; Islets of Langerhans; Lymphocytes; Male; Middle Aged; Rats; Reference Values; Treatment Failure | 1992 |
Nasal glucagon in the treatment of hypoglycaemia in type 1 (insulin-dependent) diabetic patients.
Topics: Administration, Intranasal; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Infusions, Intravenous; Injections, Intramuscular; Insulin; Male | 1992 |
Absence of the dawn phenomenon and abnormal lipolysis in type 1 (insulin-dependent) diabetic patients with chronic growth hormone deficiency.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hydroxybutyrates; Insulin Infusion Systems; Lactates; Lipolysis; Male | 1992 |
Distinct cytoplasmic islet cell antibodies with different risks for type 1 (insulin-dependent) diabetes mellitus.
Topics: Adult; Aged; Aged, 80 and over; Animals; Antibodies, Monoclonal; Autoantibodies; Autoimmune Diseases; Brain; Child; Cytoplasm; Diabetes Mellitus, Type 1; Female; Fluorescent Antibody Technique; Glucagon; Humans; Islets of Langerhans; Male; Middle Aged; Rats | 1992 |
Impaired cutaneous reactive hyperaemia during hypoglycaemia in young insulin-dependent diabetic patients and healthy controls.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Humans; Hyperemia; Hypoglycemia; Insulin; Insulin Infusion Systems; Ischemia; Male; Norepinephrine; Reference Values; Regional Blood Flow; Skin; Vasodilation | 1992 |
Effects of insulin and amino acid infusion on leucine and phenylalanine kinetics in type 1 diabetes.
Topics: Amino Acids; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Clamp Technique; Humans; Infusions, Intravenous; Insulin; Keto Acids; Kinetics; Leucine; Male; Phenylalanine | 1992 |
Hypoglycemic thresholds for cognitive dysfunction in IDDM.
Topics: Blood Glucose; Cognition; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Glucose Clamp Technique; Glycated Hemoglobin; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Reaction Time; Reference Values; Self Care | 1992 |
The ketosis-resistance in fibro-calculous-pancreatic-diabetes. 1. Clinical observations and endocrine-metabolic measurements during oral glucose tolerance test.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; C-Peptide; Cholesterol; Diabetes Mellitus; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Tolerance Test; Glycerol; Growth Hormone; Humans; Hydrocortisone; Hydroxybutyrates; Male; Multivariate Analysis; Pancreas; Reference Values; Triglycerides | 1992 |
The enteroinsular axis revisited. A novel role for an incretin.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Peptide Fragments; Peptides | 1992 |
The effect of intraperitoneal insulin delivery on carbohydrate metabolism in type 1 (insulin-dependent) diabetic patients.
Topics: Adult; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Glucagon; Humans; Infusions, Intravenous; Insulin; Insulin Infusion Systems; Male | 1992 |
Histologic finding of pancreatic islet tissue following intraportal human islet allotransplantation.
Topics: Diabetes Mellitus, Type 1; Diabetic Nephropathies; Glucagon; Humans; Inflammation; Insulin; Islets of Langerhans Transplantation; Kidney Transplantation; Liver; Portal Vein; Transplantation, Heterotopic; Transplantation, Homologous | 1992 |
Use of Lucozade and glucagon by ambulance staff for treating hypoglycaemia.
Topics: Ambulances; Diabetes Mellitus, Type 1; Emergency Medicine; Female; Glucagon; Glucose; Humans; Hypoglycemia; Inservice Training; Insulin; Male; Wales | 1992 |
Sequential metabolic studies of pancreas allograft function in type 1 diabetic recipients.
Topics: Adult; Analysis of Variance; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Eating; Female; Follow-Up Studies; Glucagon; Glucose Tolerance Test; Humans; Insulin; Kidney Transplantation; Male; Pancreas Transplantation; Regression Analysis; Transplantation, Homologous | 1992 |
Contrasting metabolic effects of continuous and pulsatile growth hormone administration in young adults with type 1 (insulin-dependent) diabetes mellitus.
Topics: 3-Hydroxybutyric Acid; Adult; Analysis of Variance; Blood Glucose; Diabetes Mellitus, Type 1; Drug Administration Schedule; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Clamp Technique; Growth Hormone; Humans; Hydroxybutyrates; Infusions, Intravenous; Insulin; Insulin Infusion Systems; Male | 1992 |
Decreased hypoglycemic effect of insulin at night in insulin-dependent diabetes mellitus and healthy subjects.
Topics: Adult; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Humans; Hypoglycemia; Insulin; Insulin Infusion Systems; Male | 1992 |
Higher glycemic thresholds for symptoms during beta-adrenergic blockade in IDDM.
Topics: Adult; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Glucose Clamp Technique; Growth Hormone; Heart Rate; Humans; Hydrocortisone; Insulin; Norepinephrine; Pancreatic Polypeptide; Propranolol; Receptors, Adrenergic, beta | 1991 |
Inherent beta-cell dysfunction induced by transgenic expression of allogeneic major histocompatibility complex class I antigen in islet cells.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Female; Gene Expression; Glucagon; H-2 Antigens; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Isoantigens; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Mice, Transgenic | 1991 |
Islet allografts in the cryptorchid testes of spontaneously diabetic BB/Wor dp rats: response to glucose, glipizide, and arginine.
Topics: Animals; Arginine; Cryptorchidism; Diabetes Mellitus, Type 1; Glipizide; Glucagon; Glucose; Glucose Tolerance Test; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Rats; Rats, Inbred BB; Testis | 1991 |
Increased somatostatin response to glucagon in insulin-dependent diabetes mellitus.
Topics: Adolescent; Adult; Blood Glucose; C-Peptide; Cross Reactions; Diabetes Mellitus, Type 1; Female; Gastrins; Glucagon; Humans; Insulin; Radioimmunoassay; Somatostatin | 1991 |
Examination of islets in the pancreas biopsy specimens from newly diagnosed type 1 (insulin-dependent) diabetic patients.
Topics: Adult; Biopsy; Diabetes Mellitus, Type 1; Female; Fluorescent Antibody Technique; Glucagon; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Humans; Insulin; Islets of Langerhans; Male; Pancreas; Pancreatic Polypeptide; Somatostatin; Staining and Labeling | 1990 |
Impairment of counterregulatory hormone responses to hypoglycemia in pregnant women with insulin-dependent diabetes mellitus.
Topics: Adult; Apgar Score; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Growth Hormone; Heart Rate, Fetal; Humans; Hydrocortisone; Hypoglycemia; Infant, Newborn; Insulin; Male; Norepinephrine; Pregnancy; Pregnancy in Diabetics | 1992 |
Impaired glucose disposal following mild hypoglycemia in nondiabetic and type I diabetic humans.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glucose Clamp Technique; Glycated Hemoglobin; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Kinetics; Male; Norepinephrine; Reference Values | 1992 |
The influence of vanadate on insulin counter-regulatory hormones in obese fa/fa rats.
Topics: Animals; Blood Glucose; Body Weight; Corticosterone; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Homeostasis; Insulin; Pancreatic Hormones; Rats; Rats, Inbred Strains; Vanadates | 1991 |
Effect of pancreas transplantation on glucose counterregulation in insulin-dependent diabetic patients prone to severe hypoglycaemia.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Growth Hormone; Humans; Hypoglycemia; Insulin; Male; Pancreas Transplantation; Time Factors | 1991 |
Serum ketone response to glucagon as a marker of insulin dependency in diabetics.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Biomarkers; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Fructosamine; Glucagon; Hexosamines; Humans; Hydroxybutyrates; Ketone Bodies; Kinetics; Male; Middle Aged; Regression Analysis | 1991 |
Glucose counterregulation in type 1 diabetic patients with decreased symptoms of hypoglycemia after insulin pump treatment.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glycated Hemoglobin; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Insulin Infusion Systems; Male; Middle Aged; Norepinephrine | 1991 |
Repetitive exposure of pancreatic islets to interleukin-1 beta. An in vitro model of pre-diabetes?
Topics: Animals; Animals, Newborn; Cells, Cultured; Diabetes Mellitus, Type 1; Disease Models, Animal; DNA; Glucagon; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Rats; Rats, Inbred Strains; Recombinant Proteins | 1991 |
Indications that branched chain amino acids, in addition to glucagon, affect the glomerular filtration rate after a high protein diet in insulin-dependent diabetes.
Topics: Adolescent; Adult; Albuminuria; Amino Acids, Branched-Chain; Biomarkers; Blood Glucose; Blood Pressure; Circadian Rhythm; Diabetes Mellitus, Type 1; Dietary Proteins; Eating; Female; Fructosamine; Glomerular Filtration Rate; Glucagon; Growth Hormone; Hexosamines; Humans; Insulin-Like Growth Factor I; Male; Renal Circulation | 1991 |
[Insulin/glucagon relationship in spontaneous diabetic remission].
Topics: Adolescent; Blood Glucose; C-Peptide; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Male; Remission Induction | 1991 |
Changes in brainstem auditory evoked potentials during insulin-induced hypoglycaemia in type 1 diabetic patients.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Evoked Potentials, Auditory, Brain Stem; Female; Glucagon; Humans; Hypoglycemia; Insulin; Insulin Infusion Systems; Male; Norepinephrine; Time Factors | 1991 |
Influence of insulin on leucine kinetics in the whole body and across the forearm in post-absorptive insulin dependent diabetic (type 1) patients.
Topics: Adult; Blood Glucose; Carbon Isotopes; Diabetes Mellitus, Type 1; Forearm; Glucagon; Humans; Insulin; Isotope Labeling; Ketone Bodies; Kinetics; Leucine; Male; Nitrogen Isotopes; Oxygen Consumption; Proteins | 1991 |
[Clinical significance of measuring serum c-peptide before and after glucagon injection].
Topics: Adult; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Male; Middle Aged | 1991 |
Renal and splanchnic exchange of human biosynthetic C-peptide in type 1 (insulin-dependent) diabetes mellitus.
Topics: Adolescent; Adult; Blood Glucose; C-Peptide; Catecholamines; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Humans; Infusions, Intravenous; Insulin; Kidney; Male; Norepinephrine; Sodium Chloride; Spleen | 1991 |
Decreased hepatic glucagon responses in type 1 (insulin-dependent) diabetes mellitus.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glycerol; Growth Hormone; Humans; Hydroxybutyrates; Infusions, Intravenous; Insulin; Insulin Secretion; Kinetics; Lactates; Liver; Male; Reference Values; Time Factors | 1991 |
Time-related, cross-sectional and prospective follow-up of pancreatic endocrine function after pancreas allograft transplantation in type 1 (insulin-dependent) diabetic patients.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Follow-Up Studies; Glucagon; Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Pancreas Transplantation; Prospective Studies; Transplantation, Homologous | 1991 |
Long-term metabolic control in recipients of combined pancreas and kidney transplants.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Follow-Up Studies; Glucagon; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Immunosuppressive Agents; Kidney Transplantation; Pancreas Transplantation; Reference Values; Uremia | 1991 |
Effect of physiological concentrations of insulin and glucagon on the relationship between nonesterified fatty acids availability and ketone body production in humans.
Topics: Absorption; Adult; Biological Availability; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Humans; Insulin; Ketone Bodies; Kinetics; Male; Osmolar Concentration; Reference Values; Regression Analysis | 1991 |
Preventive effects of octreotide (SMS 201-995) on diabetic ketogenesis during insulin withdrawal.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Fatty Acids, Nonesterified; Glucagon; Humans; Insulin; Ketone Bodies; Octreotide | 1991 |
Acute insulin response to intravenous glucose, glucagon and arginine in some subjects at risk for type 1 (insulin-dependent) diabetes mellitus.
Topics: Adolescent; Adult; Arginine; Autoantibodies; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Histocompatibility Testing; HLA-DR Antigens; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Reference Values; Risk Factors; T-Lymphocytes | 1991 |
Nocturnal electroencephalogram registrations in type 1 (insulin-dependent) diabetic patients with hypoglycaemia.
Topics: Adult; Blood Glucose; C-Peptide; Circadian Rhythm; Diabetes Mellitus, Type 1; Electrocardiography; Electroencephalography; Epinephrine; Glucagon; Glycated Hemoglobin; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin Antibodies; Norepinephrine | 1991 |
Islet hormonal regulation of glucose turnover during exercise in type 1 diabetes.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Female; Glucagon; Glucose; Homeostasis; Humans; Insulin; Insulin Infusion Systems; Islets of Langerhans; Male; Norepinephrine; Somatostatin | 1990 |
Prevention of diabetes mellitus in BB rats by neonatal stimulation of beta cells.
Topics: Animals; Animals, Newborn; Arginine; Blood Glucose; Diabetes Mellitus, Type 1; Disease Models, Animal; Glucagon; Glucose; Islets of Langerhans; Rats; Rats, Inbred BB; Time Factors | 1990 |
Glucose counterregulation in diabetes secondary to chronic pancreatitis.
Topics: Adrenergic beta-Antagonists; Blood Glucose; Blood Pressure; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucagon; Glycerol; Heart Rate; Hormones; Humans; Hydroxybutyrates; Hypoglycemia; Insulin; Lactates; Male; Middle Aged; Pancreatic Polypeptide; Pancreatitis | 1990 |
Lack of effect of hyperglycemia on lipolysis in humans.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Glycated Hemoglobin; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Insulin; Lipolysis; Male; Palmitic Acid; Palmitic Acids; Reference Values; Somatostatin | 1990 |
Improved glucose counterregulation after pancreas transplantation in diabetic patients with unawareness of hypoglycemia.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Growth Hormone; Humans; Hypoglycemia; Male; Pancreas Transplantation | 1991 |
Effects of glucagon on free fatty acid metabolism in humans.
Topics: Adipose Tissue; Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Insulin; Kinetics; Lipolysis; Male; Palmitic Acid; Palmitic Acids | 1991 |
Independent effects of youth and poor diabetes control on responses to hypoglycemia in children.
Topics: Adolescent; Adult; Age Factors; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Glucose Clamp Technique; Glycated Hemoglobin; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin Infusion Systems; Reference Values | 1991 |
Hormone response of diabetic patients to exercise at cool and warm temperatures.
Topics: Adult; Blood Glucose; Blood Pressure; Body Temperature; Cold Temperature; Diabetes Mellitus, Type 1; Exercise; Glucagon; Growth Hormone; Heart Rate; Hormones; Hot Temperature; Humans; Hydrocortisone; Kinetics; Lactates; Lactic Acid; Male; Norepinephrine; Prolactin | 1991 |
Endocrine-metabolic function in remission-phase IDDM during administration of cyclosporine.
Topics: Adolescent; Adult; Arginine; Blood Glucose; C-Peptide; Child; Cyclosporins; Diabetes Mellitus, Type 1; Eating; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucose Tolerance Test; Humans; Male; Reference Values | 1991 |
The effect of insulin withdrawal on intermediary metabolism in patients with diabetes secondary to chronic pancreatitis.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Chronic Disease; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hydroxybutyrates; Insulin; Islets of Langerhans; Ketones; Male; Middle Aged; Norepinephrine; Pancreatitis | 1991 |
The effect of acute hyperglycemia on the plasma C-peptide response to intravenous glucagon or to a mixed meal in insulin-dependent diabetes mellitus.
Topics: Acute Disease; Adolescent; Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Female; Food; Glucagon; Humans; Hyperglycemia; Injections, Intravenous; Islets of Langerhans; Male | 1991 |
Combined pancreas-kidney transplantation: preliminary results and metabolic effects.
Topics: Actuarial Analysis; Adult; Analysis of Variance; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Glucagon; Graft Survival; Humans; Immunosuppression Therapy; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Kidney; Kidney Transplantation; Male; Middle Aged | 1991 |
Opiate blockade enhances hypoglycemic counterregulation in normal and insulin-dependent diabetic subjects.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Growth Hormone; Homeostasis; Humans; Hydrocortisone; Hypoglycemia; Infusions, Intravenous; Insulin; Insulin Infusion Systems; Kinetics; Male; Naloxone; Reference Values | 1991 |
Sustained oscillatory insulin secretion after pancreas transplantation.
Topics: Activity Cycles; Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Humans; Infusions, Intravenous; Insulin; Insulin Secretion; Islets of Langerhans Transplantation; Kidney Transplantation; Male | 1990 |
[Clinical significance of plasma C-peptide analysis and the analytical method in the diagnosis of diabetes related diseases].
Topics: C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Glucagon; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Radioimmunoassay; Reference Values | 1990 |
Intra-peritoneal administration of interleukin-1 beta induces impaired insulin release from the perfused rat pancreas.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 1; Glucagon; Glucose; Injections, Intraperitoneal; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Male; Pancreas; Perfusion; Rats; Rats, Inbred WKY; Recombinant Proteins | 1990 |
Increased hepatic efficacy of urea synthesis from alanine in insulin-dependent diabetes mellitus.
Topics: Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Insulin; Kinetics; Liver; Male; Nitrogen; Urea | 1990 |
The clinical and hormonal (C-peptide and glucagon) profile and liability to ketoacidosis during nutritional rehabilitation in Ethiopian patients with malnutrition-related diabetes mellitus.
Topics: Adolescent; Adult; C-Peptide; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Ketoacidosis; Ethiopia; Female; Glucagon; Humans; Male; Middle Aged; Nutritional Physiological Phenomena; Protein-Energy Malnutrition; Reference Values | 1990 |
Reduced sensitivity to pirenzepine-induced blockade of growth hormone responses to arginine, exercise, and growth hormone-releasing hormone in type I diabetic subjects.
Topics: Adolescent; Adult; Arginine; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Exercise; Glucagon; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Kinetics; Muscarinic Antagonists; Pirenzepine; Receptors, Muscarinic | 1990 |
Insulin resistance in type 1 (insulin-dependent) diabetes: dissimilarities for glucose and intermediary metabolites.
Topics: Adult; Blood Glucose; Body Mass Index; C-Peptide; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Clamp Technique; Glycated Hemoglobin; Glycerol; Humans; Insulin; Insulin Antibodies; Insulin Resistance; Ketone Bodies; Male; Reference Values | 1990 |
Postprandial hyperglycaemia following a morning hypoglycaemia in type 1 diabetes mellitus.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Eating; Epinephrine; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Hypoglycemia; Insulin; Male | 1990 |
The possibility that pancreatic beta cell destruction leading to type 1 diabetes is initiated by the release of cytokines by polyclonal activation of the immune system.
Topics: Animals; Autoimmunity; Biological Factors; Cytokines; Diabetes Mellitus, Type 1; Freund's Adjuvant; Glucagon; Insulin; Islets of Langerhans; Macrophage Activation; Rats; Rats, Inbred Strains; Streptozocin | 1990 |
[C-peptide assays of the urine and plasma at baseline and under stimulation with glucagon in healthy subjects and diabetics].
Topics: Adult; Aged; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Humans; Middle Aged; Reference Values; Stimulation, Chemical | 1990 |
Glucose turnover and recycling in diabetes secondary to total pancreatectomy: effect of glucagon infusion.
Topics: Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Gluconeogenesis; Glucose; Humans; Infusions, Intravenous; Insulin; Lactates; Male; Middle Aged; Pancreatectomy; Pyruvates | 1990 |
Autoantibodies against insulin (IAA), C-peptide (CAA), and glucagon (GAA) in new-onset type 1 diabetic patients.
Topics: Age Factors; Autoantibodies; Body Weight; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Insulin; Islets of Langerhans; Male; Sex Factors | 1990 |
Microalbuminuria in diabetic children and adolescents. Relationship with puberty and growth hormone.
Topics: Adolescent; Age Factors; Albuminuria; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; HLA Antigens; Humans; Kidney; Male; Renin | 1990 |
Failure of nocturnal hypoglycemia to cause daytime hyperglycemia in patients with IDDM.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hydroxybutyrates; Hyperglycemia; Hypoglycemia; Insulin; Lactates; Male; Norepinephrine | 1990 |
[Plasma pancreatic glucagon assay and the clinical significance].
Topics: Arginine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucagonoma; Glucose Tolerance Test; Humans; Insulin; Pancreatic Neoplasms; Radioimmunoassay; Specimen Handling | 1990 |
[Characteristics of the postoperative period in diabetes mellitus type 1 in patients with distal splenorenal anastomosis].
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Insulin; Male; Postoperative Period; Splenorenal Shunt, Surgical | 1990 |
Characterization of the late posthypoglycemic insulin resistance in insulin-dependent diabetes mellitus.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose; Glucose Clamp Technique; Glycated Hemoglobin; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Insulin Resistance; Male; Random Allocation | 1990 |
Standard breakfast test: an alternative to glucagon testing for C-peptide reserve?
Topics: Adolescent; Adult; C-Peptide; Child; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Food, Formulated; Glucagon; Humans; Islets of Langerhans; Middle Aged | 1990 |
Leucine metabolism in IDDM. Role of insulin and substrate availability.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Epinephrine; Female; Glucagon; Glucose; Glycated Hemoglobin; Humans; Hydrocortisone; Insulin; Keto Acids; Leucine; Male; Norepinephrine | 1990 |
Physiological and pharmacological stimulation of pancreatic islet hormone secretion in type I diabetic pancreas allograft recipients.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Kidney Transplantation; Male; Middle Aged; Pancreas Transplantation; Reference Values; Transplantation, Homologous | 1990 |
Limited duration of remission of insulin dependency in children with recent overt type I diabetes treated with low-dose cyclosporin.
Topics: Adolescent; Autoantibodies; C-Peptide; Child; Cyclosporins; Diabetes Mellitus, Type 1; Female; Follow-Up Studies; Glucagon; Glucose Clamp Technique; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male | 1990 |
Glucagon, catecholamine and pancreatic polypeptide secretion in type I diabetic recipients of pancreas allografts.
Topics: Arginine; Catecholamines; Diabetes Mellitus, Type 1; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Pancreas Transplantation; Pancreatic Polypeptide; Propranolol; Secretin | 1990 |
Impaired renal response to a meat meal in insulin-dependent diabetes: role of glucagon and prostaglandins.
Topics: Adult; Diabetes Mellitus, Type 1; Dietary Proteins; Eating; Female; Glucagon; Hemodynamics; Hormones; Humans; Indomethacin; Kidney; Male; Meat; Prostaglandins; Proteinuria; Sodium | 1990 |
Glucagon-stimulated serum C-peptide levels in the early period following pancreas transplantation.
Topics: Adult; C-Peptide; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Glucagon; Graft Rejection; Humans; Kidney Transplantation; Male; Pancreas Transplantation | 1990 |
Metabolic control in recipients of duct-occluded segmental pancreatic grafts: a four-year follow-up.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Follow-Up Studies; Glucagon; Glucose Tolerance Test; Glycated Hemoglobin; Graft Survival; Humans; Immunosuppression Therapy; Kidney Transplantation; Pancreas Transplantation; Pancreatic Ducts; Postoperative Complications | 1990 |
Metabolic studies of type I diabetics after successful segmental pancreas and kidney transplantation.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Growth Hormone; Humans; Kidney Transplantation; Norepinephrine; Pancreas Transplantation; Reference Values | 1990 |
[Hypoglycemia in childhood diabetes].
Topics: Blood Glucose; Child; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Glycated Hemoglobin; Humans; Hypoglycemia; Insulin; Insulin Coma; Risk Factors | 1990 |
Inability to stimulate skeletal muscle or whole body protein synthesis in type 1 (insulin-dependent) diabetic patients by insulin-plus-glucose during amino acid infusion: studies of incorporation and turnover of tracer L-[1-13C]leucine.
Topics: 3-Hydroxybutyric Acid; Amino Acids; Blood Glucose; Carbon Isotopes; Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Hydrocortisone; Hydroxybutyrates; Insulin; Insulin-Like Growth Factor I; Isotope Labeling; Kinetics; Leucine; Male; Muscles; Protein Biosynthesis | 1990 |
Urine amylase and insulin reserve capacity are valuable tools for diagnosing pancreas allograft rejection.
Topics: Adult; Amylases; Antilymphocyte Serum; Diabetes Mellitus, Type 1; Female; Glucagon; Graft Rejection; Humans; Insulin; Islets of Langerhans; Middle Aged; Pancreatic Diseases | 1987 |
Low protein alimentation normalizes renal haemodynamic response to acute protein ingestion in type 1 diabetic children.
Topics: Adolescent; Blood Glucose; Child; Diabetes Mellitus, Type 1; Dietary Proteins; Female; Fructosamine; Glomerular Filtration Rate; Glucagon; Hexosamines; Humans; Insulin; Male; Renal Circulation | 1989 |
Pancreas transplantation: an immunohistochemical analysis of pancreatic hormones and HLA-DR expression.
Topics: Adult; Chronic Disease; Diabetes Mellitus, Type 1; Female; Glucagon; Graft Rejection; HLA-DR Antigens; Humans; Insulin; Islets of Langerhans; Male; Pancreas; Pancreas Transplantation; Pancreatic Hormones; Pancreatic Polypeptide; Pancreatitis; Somatostatin; T-Lymphocytes | 1989 |
Insulin regulation of lipolysis in nondiabetic and IDDM subjects.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Insulin; Kinetics; Lipolysis; Male; Palmitic Acid; Palmitic Acids; Reference Values; Somatostatin | 1989 |
The prevalence of impaired glucose counter-regulation during an insulin-infusion test in insulin-treated diabetic patients prone to severe hypoglycaemia.
Topics: Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glycated Hemoglobin; Growth Hormone; Homeostasis; Humans; Hydrocortisone; Hypoglycemia; Insulin Antibodies; Insulin Infusion Systems; Male; Middle Aged | 1989 |
[Experience in the use of biostator in the treatment of diabetes mellitus in children of the pubertal age].
Topics: Adolescent; Blood Glucose; Child; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Insulin Infusion Systems; Ketone Bodies; Puberty | 1989 |
Islet-cell antibodies: markers of a more severe insulin-dependent diabetes mellitus?
Topics: Adolescent; Autoantibodies; Biomarkers; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Glycated Hemoglobin; Humans; Male; Prognosis | 1989 |
The effects of SMS 201-995 (sandostatin) on metabolic profiles in insulin-dependent diabetes mellitus.
Topics: Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glycerol; Growth Hormone; Hemoglobin A; Humans; Insulin; Lactates; Male; Octreotide | 1989 |
Fate of late complications in type I diabetic patients after successful pancreas-kidney transplantation.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Diabetic Retinopathy; Female; Glucagon; Humans; Insulin; Kidney Transplantation; Male; Microcirculation; Pancreas Transplantation; Prospective Studies | 1989 |
[Nocturnal hypoglycemia with reference to hormonal counterregulation in type I diabetics receiving insulin therapy].
Topics: Adult; Aged; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Male; Middle Aged; Norepinephrine | 1989 |
Factors associated with fasting and postglucagon plasma C-peptide levels in middle-aged insulin-treated diabetic patients.
Topics: C-Peptide; Diabetes Mellitus, Type 1; Fasting; Female; Finland; Glucagon; Glycated Hemoglobin; Humans; Insulin; Male; Middle Aged; Sex Factors | 1989 |
[Role of insulin and counter-regulatory hormones in the metabolic changes caused by insulin deprivation in diabetic patients].
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Glycerol; Growth Hormone; Humans; Hydrocortisone; Hydroxybutyrates; Insulin; Male; Middle Aged | 1989 |
Fasting plasma C-peptide, glucagon stimulated plasma C-peptide, and urinary C-peptide in relation to clinical type of diabetes.
Topics: Adult; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Humans; Insulin; Insulin Secretion; Male | 1989 |
Early morning hyperglycemia in insulin-dependent diabetes: acute and sustained effects of cholinergic blockade.
Topics: Adult; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Insulin; Male; Parasympatholytics; Pirenzepine | 1989 |
Comparison of intraperitoneal and subcutaneous insulin administration on lipids, apolipoproteins, fuel metabolites, and hormones in type I diabetes mellitus.
Topics: Adult; Alanine; Apolipoproteins; Blood Glucose; Diabetes Mellitus, Type 1; Drug Administration Routes; Fatty Acids, Nonesterified; Female; Glucagon; Hormones; Humans; Hydroxybutyrates; Insulin; Lactates; Lipid Metabolism; Male | 1989 |
Pulsatile insulin infusion and glucose-homeostasis in well-controlled type 1 (insulin-dependent) diabetic patients.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Exercise Test; Female; Glucagon; Homeostasis; Humans; Injections, Intravenous; Insulin; Insulin Infusion Systems; Male; Pulsatile Flow | 1989 |
Sandostatin, a new analogue of somatostatin, reduces the metabolic changes induced by the nocturnal interruption of continuous subcutaneous insulin infusion in type 1 (insulin-dependent) diabetic patients.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Drug Administration Schedule; Fatty Acids, Nonesterified; Female; Glucagon; Glycerol; Growth Hormone; Humans; Hydroxybutyrates; Insulin; Insulin Infusion Systems; Male; Octreotide | 1989 |
B-cell responses to intravenous glucose and glucagon in non-diabetic twins of patients with type 1 (insulin-dependent) diabetes mellitus.
Topics: Adult; Autoantibodies; Blood Glucose; C-Peptide; Chronic Disease; Diabetes Mellitus, Type 1; Diseases in Twins; Female; Glucagon; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Pancreatitis; Reference Values; Risk Factors; Twins, Monozygotic | 1989 |
Glucagon in the metabolic and nutritional management after total pancreatectomy--a case report.
Topics: Amino Acids; Blood Glucose; Combined Modality Therapy; Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Male; Middle Aged; Pancreatectomy; Pancreatic Neoplasms; Postoperative Complications | 1989 |
[Indications for insulin treatment].
Topics: Diabetes Mellitus, Type 1; Diabetic Coma; Female; Glucagon; Humans; Insulin; Insulin Secretion; Pancreatic Function Tests; Pregnancy; Pregnancy in Diabetics | 1989 |
Effects of oxytocin delivery on counter-regulatory hormone response in insulin-dependent (type 1) diabetic subjects.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Hormones; Humans; Hydrocortisone; Insulin; Male; Oxytocin | 1989 |
Correlation between residual beta-cell function and islet cell antibodies in newly diagnosed type I diabetes. Follow-up study.
Topics: Adolescent; Adult; Autoantibodies; C-Peptide; Child; Diabetes Mellitus, Type 1; Female; Follow-Up Studies; Glucagon; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Parietal Cells, Gastric; Thyroid Gland | 1989 |
Hypoglycemia in IDDM.
Topics: Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Glucagon; Humans; Hypoglycemia; Insulin Resistance; Risk Factors | 1989 |
Counterregulatory hormonal responses to hypoglycaemia in type 1 (insulin-dependent) diabetes: evidence for diminished hypothalamic-pituitary hormonal secretion.
Topics: Adrenocorticotropic Hormone; Adult; Aged; beta-Endorphin; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Growth Hormone; Hormones; Humans; Hypoglycemia; Hypothalamo-Hypophyseal System; Insulin; Male; Middle Aged; Prolactin; Reference Values | 1988 |
Responses to acute insulin-induced hypoglycaemia in diabetic patients: a comparison of short-acting human and porcine insulins.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Growth Hormone; Heart Rate; Humans; Hydrocortisone; Hypoglycemia; Insulin; Insulin, Regular, Pork; Lactates; Male; Norepinephrine; Prolactin | 1988 |
Pathogenesis of the dawn phenomenon in patients with insulin-dependent diabetes mellitus. Accelerated glucose production and impaired glucose utilization due to nocturnal surges in growth hormone secretion.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Growth Hormone; Humans; Hyperglycemia; Insulin; Male; Norepinephrine; Phentolamine; Propranolol; Somatostatin; Time | 1985 |
Somatostatin and counterregulatory hormone responses to hypoglycaemia in diabetics with and without autonomic neuropathy.
Topics: Adult; Autonomic Nervous System Diseases; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Epinephrine; Female; Glucagon; Humans; Hypoglycemia; Insulin; Male; Norepinephrine; Somatostatin | 1985 |
Increased peripheral venous somatostatin concentration and decreased glucagon response to arginine in patients with insulin dependent diabetes mellitus without residual B-cell function. Increased plasma SRIF in IDDM.
Topics: Adolescent; Adult; Arginine; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; Humans; Insulin; Islets of Langerhans; Male; Somatostatin | 1985 |
Effect of twice daily subcutaneous administration of a long-acting somatostatin analog on 24-hour plasma glucose profiles in patients with insulin-dependent diabetes mellitus.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Injections, Subcutaneous; Insulin; Male; Somatostatin | 1985 |
[Diabetes mellitus and endocrine balance].
Topics: Adrenocorticotropic Hormone; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Epinephrine; Glucagon; Growth Hormone; Humans; Hydrocortisone; Somatostatin | 1986 |
Islets of Langerhans in adolescents and adults with cystic fibrosis. A quantitative study.
Topics: Adolescent; Adult; Age Factors; Child; Cystic Fibrosis; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hyperglycemia; Immunoenzyme Techniques; Insulin; Islets of Langerhans; Male; Somatostatin | 1986 |
Effect of a 12-hour subcutaneous infusion of somatostatin-14 on blood glucose, insulin and glucagon levels in healthy subjects and insulin dependent diabetics.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Infusions, Parenteral; Insulin; Radioimmunoassay; Somatostatin | 1986 |
Pancreatic islets in older patients with cystic fibrosis with and without diabetes mellitus: morphometric and immunocytologic studies.
Topics: Adolescent; Adult; Child; Cystic Fibrosis; Diabetes Mellitus, Type 1; Epithelium; Female; Glucagon; Humans; Hypertrophy; Immunoenzyme Techniques; Insulin; Islets of Langerhans; Male; Pancreatic Diseases; Somatostatin | 1986 |
Basal and meal-induced somatostatin-like immunoreactivity in healthy subjects and in IDDM and totally pancreatectomized patients. Effects of acute blood glucose normalization.
Topics: Adolescent; Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 1; Eating; Female; Gastric Inhibitory Polypeptide; Glucagon; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Pancreatectomy; Somatostatin | 1987 |
The effects of hyperglycaemia on isotopic measurement of glucose utilisation using [2(3)H], [3(3)H] and [6(14)C] glucose in patients with type 1 (insulin-dependent) diabetes mellitus.
Topics: Adult; Blood Glucose; C-Peptide; Carbon Radioisotopes; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Growth Hormone; Humans; Hyperglycemia; Insulin; Kinetics; Male; Radioisotope Dilution Technique; Reference Values; Somatostatin; Tritium | 1987 |
Prevention of the Dawn phenomenon (early morning hyperglycemia) in insulin-dependent diabetes mellitus by bedtime intranasal administration of a long-acting somatostatin analog.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Insulin; Male; Peptides, Cyclic; Somatostatin; Time Factors | 1988 |
[Metabolic consequences of a 6-hour interruption of a continuous subcutaneous insulin infusion pump in insulin-dependent diabetic patients].
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Fatty Acids, Nonesterified; Female; Glucagon; Humans; Hydroxybutyrates; Insulin Antibodies; Insulin Infusion Systems; Male; Octreotide; Risk Factors; Somatostatin; Time Factors | 1987 |
Somatostatin reduces posthypoglycemic insulin resistance in insulin-dependent diabetes mellitus.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Insulin Resistance; Male; Somatostatin | 1988 |
Pancreatic hormone secretion in chronic pancreatitis without residual beta-cell function.
Topics: Adult; Arginine; Blood Glucose; C-Peptide; Chronic Disease; Diabetes Mellitus, Type 1; Food; Glucagon; Humans; Insulin; Islets of Langerhans; Middle Aged; Pancreatic Polypeptide; Pancreatitis; Somatostatin | 1988 |
The effects of the somatostatin analogue SMS 201-995 on carbohydrate homeostasis of insulin-dependent diabetics as assessed by the artificial endocrine pancreas.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; Humans; Hypoglycemic Agents; Insulin Infusion Systems; Kinetics; Male; Octreotide; Somatostatin | 1988 |
Sulfonylurea therapy fails to diminish insulin resistance in type I-diabetic subjects.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Humans; Insulin; Insulin Resistance; Lipolysis; Liver; Male; Metabolic Clearance Rate; Middle Aged; Sulfonylurea Compounds | 1986 |
Hormonal and metabolic effects of moderate exercise in type I-diabetics with hypo- and hyperinsulinemia.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Exercise Test; Glucagon; Growth Hormone; Humans; Insulin | 1985 |
[Is glucagon a hyperglycemic agent without risk?].
Topics: Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemia; Insulin Coma; Middle Aged | 1988 |
Lack of beta-adrenergic role for catecholamines in the development of hyperglycemia and ketonaemia following acute insulin withdrawal in type I diabetic patients.
Topics: Adult; Catecholamines; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Glycerol; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Insulin; Ketone Bodies; Male; Norepinephrine; Propranolol; Receptors, Adrenergic, beta | 1985 |
Plasma pancreatic polypeptide response to insulin-induced hypoglycemia as a marker for defective glucose counterregulation in insulin-dependent diabetes mellitus.
Topics: Adult; Autonomic Nervous System Diseases; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Epinephrine; Glucagon; Glucose; Humans; Hypoglycemia; Insulin; Norepinephrine; Pancreatic Polypeptide; Peripheral Nervous System Diseases | 1985 |
Hyperglycemia after intense exercise in IDDM subjects during continuous subcutaneous insulin infusion.
Topics: 3-Hydroxybutyric Acid; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Humans; Hydroxybutyrates; Hyperglycemia; Insulin; Insulin Infusion Systems; Lactates; Male; Physical Exertion; Pyruvates; Reference Values | 1988 |
Glucagon-stimulated and postprandial plasma C-peptide values as measures of insulin secretory capacity.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Eating; Fasting; Glucagon; Humans; Insulin; Insulin Secretion; Middle Aged | 1988 |
Resting energy expenditure and food-induced thermogenesis in diabetic children receiving continuous subcutaneous insulin infusion.
Topics: Adolescent; Blood Glucose; Body Composition; Body Temperature Regulation; Child; Diabetes Mellitus, Type 1; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glucagon; Humans; Hydroxybutyrates; Insulin; Insulin Infusion Systems; Male; Oxygen Consumption; Reference Values | 1988 |
Glucagon responses to hypoglycemia in children and adolescents with IDDM.
Topics: Adolescent; Blood Glucose; Child; Diabetes Mellitus, Type 1; Glucagon; Glycated Hemoglobin; Humans; Hypoglycemia; Insulin; Kinetics | 1988 |
Urinary C-peptide: a useful tool for evaluating the endogenous insulin reserve in cohort and longitudinal studies of diabetes in childhood.
Topics: C-Peptide; Child; Cohort Studies; Diabetes Mellitus, Type 1; Glucagon; Glycosuria; Humans; Insulin; Ketone Bodies; Longitudinal Studies | 1988 |
Awareness and use of glucagon in diabetics treated with insulin.
Topics: Adult; Attitude to Health; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemia; Insulin; Male | 1986 |
Increased incidence of true type I diabetes acquired during pregnancy.
Topics: Adult; Blood Glucose; C-Peptide; Denmark; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Insulin; Longitudinal Studies; Pregnancy; Pregnancy in Diabetics; Prospective Studies; Seasons | 1987 |
Defense of euglycemia: failure in insulin-dependent diabetes.
Topics: Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Hypoglycemia; Insulin | 1987 |
Glomerulopressin activity in peripheral blood of newly diagnosed type I (insulin-dependent) diabetic patients and in normal subjects treated with glucagon.
Topics: Adolescent; Adult; Animals; Bufo arenarum; Diabetes Mellitus, Type 1; Dogs; Female; Gastric Fundus; Glomerular Filtration Rate; Glucagon; Glucuronates; Humans; Male; Muscle Contraction; Pressure; Rats; Ureter | 1986 |
Residual pancreatic beta-cell function in insulin-dependent diabetes mellitus.
Topics: Adolescent; Arginine; Child; Child, Preschool; Diabetes Mellitus, Type 1; Glucagon; Glucose Tolerance Test; Humans; Islets of Langerhans; Tolbutamide | 1987 |
[Effect of biostator control on levels of contra-insulin hormones].
Topics: Adolescent; Adult; C-Peptide; Circadian Rhythm; Diabetes Mellitus, Type 1; Glucagon; Growth Hormone; Humans; Hydrocortisone; Insulin Antagonists; Insulin Infusion Systems; Middle Aged | 1988 |
[Surgical correction of metabolism in diabetes mellitus].
Topics: Adolescent; Adult; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Male; Middle Aged; Pancreas; Splenorenal Shunt, Surgical | 1988 |
Correlation between minimal secretory capacity of pancreatic beta-cells and stability of diabetic control.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Insulin; Islets of Langerhans; Kinetics; Male; Middle Aged; Norepinephrine | 1988 |
Organ-specific autoimmunity and HLA-DR antigens as markers for beta-cell destruction in patients with type II diabetes.
Topics: Autoantibodies; Autoimmune Diseases; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Heterozygote; HLA-D Antigens; HLA-DR Antigens; HLA-DR3 Antigen; HLA-DR4 Antigen; Humans; Insulin; Islets of Langerhans; Male; Parietal Cells, Gastric; Thyroid Gland | 1988 |
Metabolic and hormonal changes in IDDM during long-distance run.
Topics: Adult; Blood Glucose; Catecholamines; Diabetes Mellitus, Type 1; Glucagon; Hormones; Humans; Hydrocortisone; Hypoglycemia; Insulin; Male; Running | 1988 |
The metabolic and hormonal effects of continuous subcutaneous insulin infusion therapy in diabetic children.
Topics: Adolescent; Blood Glucose; Child; Cholesterol, HDL; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Insulin; Insulin Infusion Systems; Ketone Bodies; Male; Time Factors; Triglycerides | 1988 |
Plasma glucose concentrations at the onset of hypoglycemic symptoms in patients with poorly controlled diabetes and in nondiabetics.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Male; Norepinephrine | 1988 |
[Cis- and trans- mutations in genetic diseases].
Topics: Diabetes Mellitus, Type 1; Gene Expression Regulation; Glucagon; Glucose; Homeostasis; Humans; Liver; Mutation; Pyruvate Kinase; Transcription Factors | 1988 |
Glucagon, not insulin, may play a secondary role in defense against hypoglycemia during exercise.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Glycerol; Growth Hormone; Heart Rate; Humans; Hydrocortisone; Hydroxybutyrates; Insulin; Lactates; Male; Norepinephrine; Oxygen Consumption; Physical Exertion | 1988 |
[Advantages of pulsatile administration of human insulin on endogenous pancreatic secretion in the normal subject and in type 1 diabetics].
Topics: Adult; Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Insulin Infusion Systems; Islets of Langerhans | 1988 |
Prevention of exercise-induced hypoglycaemia in type 1 (insulin-dependent) diabetic patients on conventional intensified insulin therapy: timing of exercise and role of counter-regulatory hormones.
Topics: Adult; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Male; Norepinephrine; Physical Exertion; Time Factors | 1988 |
Lack of influence of residual beta-cell function on the glucagon and pancreatic polypeptide secretion in type I (insulin-dependent) diabetic patients.
Topics: Adolescent; Adult; Diabetes Mellitus, Type 1; Female; Food; Glucagon; Humans; Islets of Langerhans; Male; Pancreatic Polypeptide | 1987 |
Reversing severe hypoglycemia during pregnancy with glucagon therapy.
Topics: Adult; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemia; Insulin; Pregnancy; Pregnancy Complications; Pregnancy in Diabetics; Unconsciousness | 1987 |
Metabolic control and B cell function in patients with insulin-dependent diabetes mellitus secondary to chronic pancreatitis.
Topics: Adult; C-Peptide; Chronic Disease; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Islets of Langerhans; Male; Middle Aged; Pancreatitis | 1987 |
Effects of sparteine sulfate on glucagon secretion in insulin dependent (type-1) diabetic subjects.
Topics: Adult; Arginine; Diabetes Mellitus, Type 1; Glucagon; Humans; Islets of Langerhans; Sparteine | 1987 |
Failure of nocturnal hypoglycemia to cause fasting hyperglycemia in patients with insulin-dependent diabetes mellitus.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Fasting; Female; Glucagon; Glucose; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Hypoglycemia; Insulin; Male; Norepinephrine; Time | 1987 |
[Biological significance of the endogenous secretion of insulin in response to breakfast in diabetic children].
Topics: Blood Glucose; C-Peptide; Child; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Food; Glucagon; Glycated Hemoglobin; Growth Hormone; Humans; Insulin; Male | 1987 |
Electron microscopical investigations on lymphocyte cytotoxicity against beta-cells in recent onset IDDM.
Topics: Adolescent; Adult; Animals; Antibodies, Monoclonal; Child; Cytotoxicity Tests, Immunologic; Diabetes Mellitus, Type 1; Glucagon; Humans; Immunohistochemistry; Insulin; Insulin Secretion; Islets of Langerhans; Phenotype; Rats; Rats, Inbred Strains; T-Lymphocytes, Cytotoxic | 1987 |
Hypoglycaemia in childhood diabetes. II. Effect of subcutaneous or intramuscular injection of different doses of glucagon.
Topics: Adolescent; Blood Glucose; Child; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Humans; Hydrocortisone; Hypoglycemia; Injections, Intramuscular; Injections, Subcutaneous; Male | 1988 |
Increased platelet thromboxane B2 production in newborn infants of diabetic mothers.
Topics: Blood Glucose; Blood Platelets; C-Peptide; Diabetes Mellitus, Type 1; Female; Fetal Blood; Glucagon; Humans; Infant, Newborn; Pancreas; Thromboxane B2 | 1986 |
Glucoregulation in alloxan-diabetic dogs.
Topics: Animals; Blood Glucose; Catecholamines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Dogs; Glucagon; Humans; Insulin; Liver; Phlorhizin | 1986 |
Strict nocturnal diabetic control diminishes subsequent glycemic escape during acute insulin withdrawal.
Topics: Adolescent; Adult; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glucagon; Growth Hormone; Humans; Hydrocortisone; Insulin; Ketone Bodies; Lactates; Lactic Acid; Male | 1986 |
Receptor-mediated endocytosis of polypeptide hormones is a regulated process: inhibition of [125I]iodoinsulin internalization in hypoinsulinemic diabetes of rat and man.
Topics: Adolescent; Adult; Animals; Autoradiography; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Endocytosis; Female; Glucagon; Humans; In Vitro Techniques; Insulin; Iodine Radioisotopes; Liver; Male; Radioligand Assay; Rats; Receptor, Insulin | 1986 |
Alpha cell autoantibodies: immunological and metabolic follow-up study.
Topics: Adolescent; Adult; Aged; Autoantibodies; Child; Child, Preschool; Diabetes Mellitus, Type 1; Duodenum; Female; Glucagon; Humans; Islets of Langerhans; Male; Middle Aged; Time Factors | 1986 |
Total pancreatectomy increases the metabolic response to glucagon in humans.
Topics: Adult; Amino Acids; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glycosuria; Humans; Insulin; Ketones; Male; Metabolism; Middle Aged; Pancreatectomy | 1986 |
The metabolic response to insulin deprivation in idiopathic brittle diabetes.
Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hydroxybutyrates; Insulin; Norepinephrine; Time Factors | 1986 |
The role of insulin antibodies in insulin treatment of type I diabetes.
Topics: Adolescent; C-Peptide; Child; Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Insulin; Insulin Antibodies; Mathematics | 1986 |
Polyneuropathy and hormone profiles in a chow puppy with hypoplasia of the islets of Langerhans.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Dog Diseases; Dogs; Female; Glucagon; Insulin; Islets of Langerhans | 1986 |
Glucagon responses to L-arginine and insulin after treatment of insulin dependent diabetes mellitus in childhood.
Topics: Adolescent; Arginine; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemia; Insulin; Male | 1986 |
Endocrine pancreatic function in insulin-dependent diabetic pregnant women.
Topics: Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Islets of Langerhans; Pregnancy; Pregnancy in Diabetics | 1986 |
Diminished A-cell secretion in the early phase of type I diabetes mellitus.
Topics: Adolescent; Adult; Arginine; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Twins, Monozygotic | 1986 |
Plasma and urinary C-peptide in the classification of adult diabetics.
Topics: Adolescent; Adult; Aged; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Glucagon; Humans; Insulin; Insulin Secretion; Middle Aged | 1986 |
[Mechanism of the blunted glucagon response to insulin-induced hypoglycemia in diabetics].
Topics: Adolescent; Adult; Aged; Autonomic Nervous System; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Hypoglycemia; Insulin; Male; Middle Aged; Shy-Drager Syndrome | 1986 |
Adrenergic modulation of potassium metabolism during exercise in normal and diabetic humans.
Topics: Adult; Bicarbonates; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Humans; Insulin; Kinetics; Male; Norepinephrine; Phentolamine; Physical Exertion; Potassium; Propranolol; Reference Values; Sodium | 1987 |
The effect of biosynthetic human proinsulin on the hepatic response to glucagon in insulin-deficient diabetes.
Topics: Adult; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Insulin; Liver; Male; Middle Aged; Proinsulin; Swine | 1987 |
Plasma C-peptide and insulin responses to intravenous glucagon stimulation in idiopathic haemochromatosis.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Hemochromatosis; Humans; Insulin; Male; Middle Aged; Time Factors | 1987 |
Estimation of B-cell function by the urinary excretion rate of C-peptide in diabetic patients: comparison with C-peptide response to glucagon and to a mixed meal.
Topics: Adult; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Food; Glucagon; Humans; Islets of Langerhans; Male; Obesity | 1987 |
Cytotoxic activity of sera from diabetic BB rats against BB rat islet--a functional study.
Topics: Animals; Animals, Suckling; Autoantibodies; Cell Division; Cytotoxicity, Immunologic; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; DNA; Glucagon; Insulin; Islets of Langerhans; Rats; Rats, Brattleboro; Rats, Mutant Strains | 1987 |
Clinical characteristics in the discrimination between patients with low or high C-peptide level among middle-aged insulin-treated diabetics.
Topics: Blood Glucose; Body Weight; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Humans; Male; Middle Aged; Sex Factors | 1987 |
Exaggerated epinephrine responses to hypoglycemia in normal and insulin-dependent diabetic children.
Topics: Adult; Blood Glucose; Child; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Glucose; Glycated Hemoglobin; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin Antibodies; Norepinephrine; Time Factors | 1987 |
Exercise and the management of diabetes mellitus.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Energy Metabolism; Fatty Acids, Nonesterified; Glucagon; Glucose; Humans; Hyperglycemia; Hypoglycemia; Ketone Bodies; Physical Exertion | 1987 |
Outcome of the glucagon test depends upon the prevailing blood glucose concentration in type I (insulin-dependent) diabetic patients.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Fasting; Female; Food; Glucagon; Humans; Male | 1987 |
Practical aspects in performing the glucagon test in the measurement of C-peptide secretion in diabetic patients.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Food; Glucagon; Humans; Male; Middle Aged | 1986 |
[The dawn phenomenon could be due to nictemeral rhythms in the peripheral metabolism of insulin].
Topics: Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Glucagon; Growth Hormone; Humans; Hydrocortisone; Insulin Infusion Systems | 1986 |
Congenital pancreatic hypoplasia: a syndrome of exocrine and endocrine pancreatic insufficiency.
Topics: Adult; C-Peptide; Diabetes Mellitus, Type 1; Glucagon; HLA Antigens; Humans; Male; Pancreas | 1986 |
Rate of glucose fall does not affect counterregulatory hormone responses to hypoglycemia in normal and diabetic humans.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Male; Middle Aged; Norepinephrine | 1987 |
The significance of impaired pancreatic polypeptide and epinephrine responses to hypoglycemia in patients with insulin-dependent diabetes mellitus.
Topics: Adolescent; Adult; Autonomic Nervous System; Cardiovascular System; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Epinephrine; Glucagon; Humans; Hypoglycemia; Pancreatic Polypeptide; Reflex, Abnormal | 1987 |
Plasma glucagon and glucagon-like immunoreactive components in Type 1 (insulin-dependent) diabetic patients and normal subjects before and after an oral glucose load.
Topics: Adult; Amino Acid Sequence; Chromatography, Gel; Diabetes Mellitus, Type 1; Female; Glucagon; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Male; Peptides | 1985 |
The importance of plasma free insulin and counterregulatory hormones for the recovery of blood glucose following hypoglycaemia in type 1 diabetics.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Insulin; Insulin Antibodies; Male; Middle Aged; Norepinephrine | 1985 |
alpha-Glucosidase inhibition improves postprandial hyperglycemia and decreases insulin requirements in insulin-dependent diabetes mellitus.
Topics: Absorption; Acarbose; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Drug Administration Schedule; Female; Food; Glucagon; Glucose; Glucosidases; Glycoside Hydrolase Inhibitors; Humans; Hyperglycemia; Insulin; Insulin Infusion Systems; Male; Oligosaccharides; Trisaccharides; Xylose | 1985 |
Serum magnesium in insulin-dependent diabetics and healthy subjects in relation to insulin secretion and glycemia during glucose-glucagon test.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Insulin; Insulin Secretion; Magnesium | 1985 |
Muscular exercise in type I-diabetics. II. Hormonal and metabolic responses to moderate exercise.
Topics: Adult; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glucagon; Glycerol; Growth Hormone; Heart Rate; Humans; Injections, Subcutaneous; Insulin; Physical Exertion | 1985 |
Normalization by sodium salicylate of the impaired counterregulatory glucagon response to hypoglycemia in insulin-dependent diabetes. A possible role for endogenous prostaglandins.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemia; Insulin; Male; Prostaglandins; Sodium Salicylate; Time Factors | 1985 |
Variable deterioration in cortical function during insulin-induced hypoglycemia.
Topics: Adult; Autonomic Nervous System Diseases; Blood Glucose; Cerebral Cortex; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Epinephrine; Female; Glucagon; Humans; Hydrocortisone; Hypoglycemia; Insulin; Male; Reaction Time | 1985 |
Intensive insulin therapy reduces counterregulatory hormone responses to hypoglycemia in patients with type I diabetes.
Topics: Adult; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Glycated Hemoglobin; Growth Hormone; Homeostasis; Humans; Hydrocortisone; Hypoglycemia; Insulin; Insulin Infusion Systems; Middle Aged; Norepinephrine | 1985 |
Comparison of insulin-mediated and glucose-mediated glucose disposal in patients with insulin-dependent diabetes mellitus and in nondiabetic subjects.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose; Growth Hormone; Humans; Hydrocortisone; Insulin; Male; Norepinephrine | 1985 |
Hyperalaninaemia is an early feature of diabetes secondary to total pancreatectomy.
Topics: Adenocarcinoma; Adult; Aged; Alanine; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Insulin; Insulin Infusion Systems; Intraoperative Period; Lactates; Male; Middle Aged; Pancreatectomy; Pancreatic Neoplasms; Pyruvates | 1985 |
First-degree relatives of patients with type I diabetes mellitus. Islet-cell antibodies and abnormal insulin secretion.
Topics: Autoantibodies; Diabetes Mellitus, Type 1; Diseases in Twins; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Prospective Studies | 1985 |
Free insulin levels and metabolic effects of meal-time bolus and square-wave intraperitoneal insulin infusion in insulin-dependent diabetic patients.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Food; Glucagon; Glycerol; Humans; Hydrocortisone; Hydroxybutyrates; Insulin; Insulin Infusion Systems; Kinetics; Lactates; Lactic Acid; Male; Peritoneum | 1985 |
C-peptide determination in the choice of treatment in diabetes mellitus.
Topics: Adolescent; Adult; Aged; Body Weight; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Humans; Insulin; Middle Aged | 1985 |
Glucose counterregulation in normal and diabetic man.
Topics: Autonomic Nervous System Diseases; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Epinephrine; Glucagon; Humans; Hypoglycemia; Insulin | 1985 |
[Secretion of pancreatic polypeptide and glucagon in patients with diabetes mellitus after the administration of insulin].
Topics: Adult; Aged; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Insulin; Male; Middle Aged; Pancreas; Pancreatic Function Tests; Pancreatic Polypeptide | 1985 |
The mechanism of exaggerated glucagon response to arginine in diabetes mellitus.
Topics: Adult; Aged; Arginine; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Humans; Insulin; Insulin Infusion Systems; Kinetics; Middle Aged | 1985 |
A comparison of serum C-peptide response to intravenous glucagon, and urine C-peptide, as indexes of insulin dependence.
Topics: C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fasting; Glucagon; Humans; Insulin; Kinetics; Sulfonylurea Compounds | 1985 |
Metabolic control of type I (insulin dependent) diabetes after pancreas transplantation.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hydroxybutyrates; Immunosuppression Therapy; Insulin; Kidney Transplantation; Lactates; Male; Pancreas Transplantation | 1985 |
The C-peptide response to glucagon injections in IDDM and NIDDM patients.
Topics: C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fasting; Glucagon; Humans | 1985 |
[Causes of insulin resistance in type 1 diabetes].
Topics: Animals; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Growth Hormone; Humans; Hydrocortisone; Insulin Antibodies; Insulin Resistance; Osmolar Concentration; Rats | 1985 |
Hormonal responses to exercise in diabetic and nondiabetic pregnant patients.
Topics: Adult; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Heart Rate; Humans; Norepinephrine; Physical Exertion; Pregnancy; Pregnancy in Diabetics | 1985 |
Does central nervous system adaptation to antecedent glycemia occur in patients with insulin-dependent diabetes mellitus?
Topics: Adaptation, Physiological; Blood Glucose; Brain; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Homeostasis; Humans; Hypoglycemia | 1985 |
The glomerular hyperfiltration of diabetes is not associated with elevated plasma levels of glucagon and growth hormone.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Glomerular Filtration Rate; Glucagon; Glycated Hemoglobin; Glycosuria; Growth Hormone; Humans; Male; Middle Aged | 1985 |
Letter: Glucagon antibodies in diabetic patients.
Topics: Adolescent; Adult; Antibodies; Binding Sites, Antibody; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; In Vitro Techniques; Insulin; Iodine Radioisotopes; Male | 1974 |
Islet-cells and insulin.
Topics: Biological Assay; Carbohydrate Metabolism; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; Humans; Immunoassay; Insulin; Islets of Langerhans | 1967 |
The effect of crude secretin in maturity-onset diabetes mellitus.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; Glucose Tolerance Test; Humans; Injections, Intravenous; Insulin; Middle Aged; Prediabetic State; Secretin | 1967 |
[The diabetic disease (M.D.). Clinical picture and complications].
Topics: Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Coma; Diabetic Ketoacidosis; Diabetic Nephropathies; Diabetic Retinopathy; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Insulin Antibodies; Ketone Bodies; Radioimmunoassay; Tolbutamide | 1974 |
Trauma: hormonal factors with special reference to diabetes mellitus.
Topics: Adipose Tissue; Adrenocorticotropic Hormone; Blood Glucose; Catecholamines; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Dwarfism, Pituitary; Epinephrine; Glucagon; Growth Hormone; Humans; Insulin; Liver; Muscles; Pancreas; Pituitary Hormones, Anterior; Preoperative Care; Stress, Physiological; Time Factors; Wounds and Injuries | 1974 |
[Influence of glucagon on jejunal absorption of glucose, water and electrolytes in man (author's transl)].
Topics: Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Insulin; Intestinal Absorption; Jejunum; Potassium; Sodium; Water; Water-Electrolyte Balance | 1974 |
B-pancreatic function in obese and diabetic children.
Topics: Arginine; Blood Glucose; Child; Diabetes Mellitus, Type 1; Ethylenediamines; Female; Glucagon; Glucose Tolerance Test; Humans; Injections, Intravenous; Insulin; Islets of Langerhans; Male; Obesity; Theophylline; Tolbutamide | 1972 |
Lack of glucagon response to hypoglycemia in diabetes: evidence for an intrinsic pancreatic alpha cell defect.
Topics: Adolescent; Adult; Aged; Arginine; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Islets of Langerhans; Male; Middle Aged | 1973 |
Hyperglucagonemia in diabetic ketoacidosis. Its prevalence and significance.
Topics: Acetone; Adolescent; Adult; Aged; Blood Glucose; Blood Urea Nitrogen; Carbon Dioxide; Child; Chlorides; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Female; Glucagon; Humans; Hydrogen-Ion Concentration; Insulin; Male; Middle Aged; Osmolar Concentration; Potassium; Respiration; Sodium; Time Factors | 1973 |
[The effect of glucagon on metabolism].
Topics: Acute Disease; Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucagon; Hepatitis; Humans; Male; Obesity | 1972 |
Hormonal influences on the concentration of tyrosine in blood.
Topics: Acromegaly; Adolescent; Androgens; Contraceptives, Oral; Diabetes Mellitus, Type 1; Epinephrine; Fasting; Female; Glucagon; Glucose; Glucose Tolerance Test; Hormones; Humans; Hyperthyroidism; Hypoglycemia; Hypothyroidism; Insulin; Male; Pregnancy; Sex Factors; Tyrosine | 1972 |
Determination of pancreatic and gut glucagon-like immunoreactivity (GLI) in normal and diabetic subjects.
Topics: Administration, Oral; Adolescent; Adult; Aged; Animals; Antigen-Antibody Reactions; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Glucose Tolerance Test; Humans; Intestines; Iodine Radioisotopes; Male; Middle Aged; Pancreas; Rabbits; Radioimmunoassay | 1972 |
The intravenous glucose tolerance test in chemical diabetes.
Topics: Adolescent; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Evaluation Studies as Topic; Glucagon; Glucose; Glucose Tolerance Test; Humans; Injections, Intravenous; Prediabetic State | 1973 |
Relationship between diabetes mellitus and obesity in the child.
Topics: Adolescent; Arginine; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Follow-Up Studies; Glucagon; Glucose Tolerance Test; Humans; Insulin; Male; Obesity | 1973 |
[Analysis of blood sugar curves following glucagon load in diabetic children].
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Glucagon; Humans | 1973 |
Plasma insulin and glucose profiles in normal, obese, and diabetic persons.
Topics: Adolescent; Adult; Aged; Blood Glucose; Carbohydrate Metabolism, Inborn Errors; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Eating; Fasting; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Obesity | 1973 |
Insulin response to glucagon in diabetic children.
Topics: Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Fasting; Glucagon; Humans; Hyperglycemia; Injections, Intravenous; Insulin; Insulin Secretion; Prospective Studies; Time Factors | 1973 |
[Accuracy of radioimmunologic insulin determination].
Topics: Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Insulin; Iodine Isotopes; Isotope Labeling; Pancreas; Pancreatectomy; Radioimmunoassay; Tolbutamide | 1974 |
Glucagon mediation of growth hormone secretion in juvenile diabetes mellitus.
Topics: Adolescent; Blood Glucose; Body Weight; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; Humans; Hyperglycemia; Injections, Intravenous; Male; Methods; Propranolol; Stimulation, Chemical; Time Factors | 1974 |
Pancreatic glucagon secretion in normal and diabetic subjects.
Topics: Adult; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; Humans; Islets of Langerhans; Male; Middle Aged; Pancreas; Pancreatitis; Radioimmunoassay | 1969 |
Glucose intolerance in cystic fibrosis.
Topics: Adolescent; Adult; Blood Glucose; Child; Cystic Fibrosis; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; Glucose; Glucose Tolerance Test; Growth Hormone; Humans; Insulin; Islets of Langerhans; Pancreas; Phentolamine; Tolbutamide | 1969 |
Abnormal alpha-cell function in diabetes. Response to carbohydrate and protein ingestion.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Dietary Carbohydrates; Dietary Proteins; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Islets of Langerhans; Male | 1970 |
[Abnormal alpha cell function in diabetes mellitus].
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 1; Dietary Carbohydrates; Dietary Proteins; Glucagon; Humans; Islets of Langerhans | 1970 |
[Therapy of juvenile diabetes].
Topics: Adolescent; Child; Diabetes Mellitus, Type 1; Diabetic Coma; Diabetic Ketoacidosis; Diet Therapy; Dietary Carbohydrates; Glucagon; Glycosuria; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Physical Education and Training; Vaccination | 1969 |
Studies of pancreatic alpha cell function in normal and diabetic subjects.
Topics: Adolescent; Adult; Arginine; Body Weight; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Diabetic Nephropathies; Fasting; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Middle Aged; Pancreas; Radioimmunoassay | 1970 |
[The effect of glucagon on metabolism].
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Male | 1972 |
Glucagon antibodies after long-term insulin treatment in a diabetic child.
Topics: Adolescent; Animals; Antibodies; Diabetes Mellitus, Type 1; Glucagon; Guinea Pigs; Humans; Insulin; Iodine Isotopes; Male; Radioimmunoassay | 1972 |
Studies of diabetic instability. II. Tests of insulinogenic reserve with infusions of arginine, glucagon, epinephrine, and saline.
Topics: Adult; Aged; Arginine; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Eating; Epinephrine; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Humans; Insulin; Insulin Secretion; Ketone Bodies; Male; Middle Aged; Physical Exertion; Radioimmunoassay; Rest; Sodium Chloride | 1971 |
[Current events 1971 in the area of diabetes].
Topics: Animals; Canada; Diabetes Mellitus; Diabetes Mellitus, Type 1; Dogs; Drug Compounding; Europe; Female; Glucagon; Humans; Injections, Intravenous; Insulin; Male; Sulfonylurea Compounds; United States | 1971 |
[Physiology and physiopathology of the endocrine pancreas].
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Langerhans Cells; Pancreas; Prediabetic State | 1971 |
Diurnal patterns of blood glucose, serum free fatty acids, insulin, glucagon and growth hormone in normals and juvenile diabetics.
Topics: Adolescent; Adult; Blood Glucose; Child; Circadian Rhythm; Colorimetry; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glucagon; Growth Hormone; Humans; Insulin; Male; Methods; Radioimmunoassay | 1970 |
[Reflections on the role of education in the treatment of young diabetics].
Topics: Attitude to Health; Child; Diabetes Mellitus, Type 1; Diet Therapy; Family; Glucagon; Health Education; Humans; Hypoglycemia; Insulin; Self Medication | 1970 |
Studies on the radioimmunological determination of blood insulin by means of 125-I-insulin of high specific activity.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Fasting; Female; Glucagon; Glucose; Humans; Infant; Insulin; Iodine Isotopes; Leucine; Methods; Obesity; Radioimmunoassay; Swine; Tolbutamide | 1970 |
Glucagon-induced growth hormone release in children.
Topics: Adolescent; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; Humans; Male; Obesity | 1970 |
Evolution of diabetes mellitus from hypoglycemia.
Topics: Adolescent; Blood Glucose; Child; Chronic Disease; Diabetes Mellitus, Type 1; Drug Tolerance; Female; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Male; Tolbutamide | 1971 |
[Problems of the pathogenesis and prospects of the study of diabetes mellitus in children].
Topics: Antibody Formation; Carbohydrate Metabolism; Child; Diabetes Mellitus, Type 1; Glucagon; Glucocorticoids; Humans; Insulin Antibodies; Insulin Resistance | 1967 |
Endogenous insulin and growth hormone response in children with newly diagnosed diabetes mellitus.
Topics: Adolescent; Arginine; Carbon Dioxide; Child; Child, Preschool; Chlorides; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Growth Hormone; Humans; Hydrogen; Infant; Insulin; Insulin Secretion; Male; Partial Pressure; Potassium; Sodium; Stimulation, Chemical; Tolbutamide | 1968 |
[Plasma concentrations of insulin and free fatty acids in juvenile diabetes after loading with tolbutamide and glucagon].
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Fatty Acids; Glucagon; Humans; Insulin Antibodies; Tolbutamide | 1968 |
Insulin reserve in children with chemical diabetes.
Topics: Child; Diabetes Mellitus, Type 1; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Prediabetic State | 1969 |
Changes in plasma insulin and glucose tolerance in stable diabetes in a young woman.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Male; Tolbutamide | 1969 |
Chemical and early overt diabetes mellitus in children. I. Effect of glucagon on "insulin reserve".
Topics: Adolescent; Adult; Blood Glucose; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Glucose Tolerance Test; Humans; Insulin; Male; Prediabetic State | 1969 |
[Hypoglycemia in young diabetics].
Topics: Adolescent; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hypoglycemia; Infant; Male | 1965 |
Preserved GLP-I effects on glycogen synthase a activity and glucose metabolism in isolated hepatocytes and skeletal muscle from diabetic rats.
Topics: Animals; Animals, Newborn; Carbon Radioisotopes; Cells, Cultured; Cohort Studies; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon-Like Peptides; Glucose; Glycogen Synthase; Insulin; Liver; Muscle, Skeletal; Pancreatic Hormones; Peptides; Phosphorylases; Rats; Rats, Wistar | 1997 |
Regulation of peripheral plasma somatostatin like immunoreactivity in type I diabetes: role of the degree of metabolic control.
Topics: Adolescent; Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 1; Drug Administration Schedule; Fatty Acids, Nonesterified; Female; Glucagon-Like Peptides; Humans; Insulin; Insulin, Regular, Pork; Ketone Bodies; Male; Middle Aged; Peptides | 1986 |