Page last updated: 2024-10-28

glipizide and Endotoxemia

glipizide has been researched along with Endotoxemia in 3 studies

Glipizide: An oral hypoglycemic agent which is rapidly absorbed and completely metabolized.
glipizide : An N-sulfonylurea that is glyburide in which the (5-chloro-2-methoxybenzoyl group is replaced by a (5-methylpyrazin-2-yl)carbonyl group. An oral hypoglycemic agent, it is used in the treatment of type 2 diabetes mellitus.

Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.

Research Excerpts

ExcerptRelevanceReference
" The present study was designed as a prospective and controlled laboratory experiment to elucidate the short-term effects of glipizide, a specific K(ATP) channel inhibitor, on cardiopulmonary hemodynamics and global oxygen transport in healthy sheep and sheep with endotoxemia."3.73Short-term effects of glipizide (an adenosine triphosphate-sensitive potassium channel inhibitor) on cardiopulmonary hemodynamics and global oxygen transport in healthy and endotoxemic sheep. ( Bone, HG; Bröking, K; Daudel, F; Lange, M; Salzman, AL; Szabo, C; Traber, DL; Van Aken, H; Westphal, M; Williams, W, 2006)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hessler, M1
Pinto, BB1
Arnemann, PH1
Kampmeier, TG1
Seidel, L1
Morelli, A2
Van Aken, H3
Westphal, M3
Rehberg, S1
Ertmer, C2
Lange, M2
Szabo, C1
Williams, W2
Traber, DL2
Daudel, F2
Bröking, K2
Salzman, AL1
Bone, HG2
Hucklenbruch, C1
Stubbe, H1

Other Studies

3 other studies available for glipizide and Endotoxemia

ArticleYear
Differential Effects of Selective and Nonselective Potassium Channel Inhibitors in Ovine Endotoxemic Shock (Macrocirculation) and in a Rat Model of Septic Shock (Microcirculation).
    Shock (Augusta, Ga.), 2019, Volume: 51, Issue:2

    Topics: Animals; Endotoxemia; Female; Glipizide; Male; Microcirculation; Potassium Channel Blockers; Rats; R

2019
Short-term effects of glipizide (an adenosine triphosphate-sensitive potassium channel inhibitor) on cardiopulmonary hemodynamics and global oxygen transport in healthy and endotoxemic sheep.
    Shock (Augusta, Ga.), 2006, Volume: 26, Issue:5

    Topics: Adenosine Triphosphate; Animals; Biological Transport; Endotoxemia; Female; Glipizide; Heart; Lung;

2006
Continuously infused glipizide reverses the hyperdynamic circulation in ovine endotoxemia.
    Shock (Augusta, Ga.), 2007, Volume: 27, Issue:6

    Topics: Adenosine Triphosphate; Animals; Disease Models, Animal; Endotoxemia; Endotoxins; Female; Glipizide;

2007