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glipizide and Diabetes Mellitus

glipizide has been researched along with Diabetes Mellitus in 76 studies

Glipizide: An oral hypoglycemic agent which is rapidly absorbed and completely metabolized.
glipizide : An N-sulfonylurea that is glyburide in which the (5-chloro-2-methoxybenzoyl group is replaced by a (5-methylpyrazin-2-yl)carbonyl group. An oral hypoglycemic agent, it is used in the treatment of type 2 diabetes mellitus.

Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.

Research Excerpts

ExcerptRelevanceReference
"In 2009, the Veterans Health Administration (VHA) released a national bulletin regarding the risk of hypoglycemia associated with the use of glyburide in elderly patients with renal dysfunction."7.77Glycemic control and hypoglycemia in Veterans Health Administration patients converted from glyburide to glipizide. ( Cantrell, M; Egge, JA; Shaw, RF; Skoff, RA; Waterbury, NV, 2011)
"To study some aspects of locally and extraocularly administered methylprednisolone on diffuse diabetic macular edema."7.72Retrobulbar injection of methylprednisolone in diffuse diabetic macular edema. ( Knudsen, LL, 2004)
"Serum fructosamine and blood GHb concentrations are clinically useful tools for monitoring control of glycemia in cats with diabetes mellitus."7.70Comparison of serum fructosamine and blood glycosylated hemoglobin concentrations for assessment of glycemic control in cats with diabetes mellitus. ( Elliott, DA; Feldman, EC; Neal, LA; Nelson, RW; Reusch, CE, 1999)
"Plasma lipid concentration and lipoprotein composition were studied before and after several months of glipizide treatment in 23 patients with non-insulin-dependent diabetes mellitus."7.66Lipid metabolism in non-insulin-dependent diabetes mellitus: effect of glipizide therapy. ( Doberne, L; Greenfield, MS; Reaven, GM; Rosenthal, M; Vreman, HJ, 1982)
"Studies in patients with insulin independent diabetes indicate that treatment with the second generation sulfonylurea glipizide results in partial amelioration of their insulin resistance and that this effect is significant in glipizide's antidiabetic action."7.66Insulin resistance in patients with insulin independent diabetes mellitus: partial amelioration by the sulfonylurea glipizide. ( Feinglos, MN; Lebovitz, H, 1979)
"This study was designed to compare the efficacy of acute premeal administration of glipizide versus nateglinide in controlling postprandial hyperglycemia in subjects with non-insulin-requiring type 2 diabetes."5.10Control of postprandial hyperglycemia: optimal use of short-acting insulin secretagogues. ( Burge, MR; Carroll, MF; Izard, A; Riboni, K; Schade, DS, 2002)
"The addition of sibutramine to oral hypoglycemic therapy resulted in significant weight loss and improvement in metabolic parameters in this patient group."5.09Effects of sibutramine in obese female subjects with type 2 diabetes and poor blood glucose control. ( Ertorer, EM; Gokcel, A; Guvener, N; Karakose, H; Tanaci, N; Tutuncu, NB, 2001)
"In 13 patients with maturity-onset diabetes mellitus which did not respond to diet therapy alone, serum concentration of glipizide, blood glucose (B-G) concentration, serum immunoreactive insulin (S-IRI) and plasma glycerol (P-G) were monitored hourly over 12 hours after placebo, an initial dose of glipizide (5 mg p."5.05The antidiabetic effect and pharmacokinetic properties of glipizide. Comparison of a single dose with divided dose regime. ( Christenson, I; Jansson, B; Ostman, J; Weiner, L, 1981)
" All of them had maturity-onset diabetes mellitus and were on sulfonylurea drugs (tolbutamide or glipizide)."5.05A study of the possible interaction of indoprofen with hypoglycemic sulfonylureas in diabetic patients. ( Bommartini, F; Emanueli, A; Freddo, J; Pedrazzi, F, 1981)
"In 2009, the Veterans Health Administration (VHA) released a national bulletin regarding the risk of hypoglycemia associated with the use of glyburide in elderly patients with renal dysfunction."3.77Glycemic control and hypoglycemia in Veterans Health Administration patients converted from glyburide to glipizide. ( Cantrell, M; Egge, JA; Shaw, RF; Skoff, RA; Waterbury, NV, 2011)
"A simple elementary osmotic pump (EOP) system that could deliver metformin hydrochloride (MT) and glipizide (GZ) simultaneously for extended periods of time was developed in order to reduce the problems associated with multidrug therapy of type 2 non-insulin-dependent diabetes mellitus."3.73Design and evaluation of compound metformin/glipizide elementary osmotic pump tablets. ( Guo, H; Li, W; Liu, H; Nie, S; Ouyang, D; Pan, W, 2005)
"To study some aspects of locally and extraocularly administered methylprednisolone on diffuse diabetic macular edema."3.72Retrobulbar injection of methylprednisolone in diffuse diabetic macular edema. ( Knudsen, LL, 2004)
"Glipizide is an oral antidiabetic drug that has been used in the treatment of post-transplant diabetes mellitus (PTDM)."3.70Glipizide treatment of post-transplant diabetes does not interfere with cyclosporine pharmacokinetics in renal allograft recipients. ( Asberg, A; Berg, KJ; Bergan, S; Hartmann, A; Sagedal, S, 1998)
"Serum fructosamine and blood GHb concentrations are clinically useful tools for monitoring control of glycemia in cats with diabetes mellitus."3.70Comparison of serum fructosamine and blood glycosylated hemoglobin concentrations for assessment of glycemic control in cats with diabetes mellitus. ( Elliott, DA; Feldman, EC; Neal, LA; Nelson, RW; Reusch, CE, 1999)
"The effect of glipizide treatment on diabetic control and on in vivo insulin secretion and action was studied in 20 patients with non-insulin-dependent diabetes mellitus (NIDDM)."3.66Effect of sulfonylurea treatment on in vivo insulin secretion and action in patients with non-insulin-dependent diabetes mellitus. ( Doberne, L; Greenfield, MS; Reaven, GM; Rosenthal, M; Schulz, B; Widstrom, A, 1982)
"Plasma lipid concentration and lipoprotein composition were studied before and after several months of glipizide treatment in 23 patients with non-insulin-dependent diabetes mellitus."3.66Lipid metabolism in non-insulin-dependent diabetes mellitus: effect of glipizide therapy. ( Doberne, L; Greenfield, MS; Reaven, GM; Rosenthal, M; Vreman, HJ, 1982)
"Studies in patients with insulin independent diabetes indicate that treatment with the second generation sulfonylurea glipizide results in partial amelioration of their insulin resistance and that this effect is significant in glipizide's antidiabetic action."3.66Insulin resistance in patients with insulin independent diabetes mellitus: partial amelioration by the sulfonylurea glipizide. ( Feinglos, MN; Lebovitz, H, 1979)
" Mean initial dosage was 7."2.64Glipizide in the treatment of maturity-onset diabetes: a multi-centre, out-patient study. ( Fowler, LK, 1978)
"The clinically effective duration of blood glucose lowering action of a new hypoglycaemic sulphonylurea, glipizide, given in single before breakfast dosage (up to 20 mg) has been studied in 20 apparently insulin-independent diabetics."2.64[Duration of effective hypoglycaemic action of glipizide given once daily (author's transl)]. ( Azzopardi, J; Campbell, IW; Clarke, BF; Duncan, LJ, 1975)
"Glipizide is a second generation of sulphonylurea compound, effective in lowering of blood glucose, well-tolerated as well as safe during long-term treatment."2.39[Glipizide--a short-acting sulphonylurea derivative]. ( Ogonowski, J, 1996)
"Glipizide is a 'second generation' oral hypoglycaemic agent similar in potency to glibenclamide."2.36Glipizide: a review of its pharmacological properties and therapeutic use. ( Avery, GS; Brogden, RN; Heel, RC; Pakes, GE; Speight, TM, 1979)
"Hypoglycemia was defined as hospital admission or an emergency department visit for hypoglycemia or as an outpatient blood glucose <60 mg/dL."1.48Risk of Hypoglycemia Following Hospital Discharge in Patients With Diabetes and Acute Kidney Injury. ( Abdel-Kader, K; Greevy, RA; Griffin, MR; Horner, J; Hung, AM; Ikizler, TA; Matheny, ME; Parr, SK; Perkins, AM; Roumie, CL; Siew, ED; Speroff, T; Wilson, OD, 2018)
"Treatment with metformin and glipizide during in vitro albumin glycation significantly reduced the formation of glycation adducts and inhibited structural modifications."1.43Antiglycation and cell protective actions of metformin and glipizide in erythrocytes and monocytes. ( Adeshara, K; Tupe, R, 2016)
" The mean elimination half-life was 4."1.26Glipizide pharmacokinetics and response in diabetics. ( Huupponen, R; Iisalo, E; Seppälä, P, 1982)
" Food did not affect the bioavailability of any of the four drugs, but delayed Gz absorption."1.26Kinetics-effect relations of glipizide and other sulfonylureas. ( Melander, A; Sartor, G; Scherstén, B; Wåhlin-Boll, E, 1980)
" In accordance with the augmented physiologic insulin release in the morning, a single morning dose of sulfonylureas may be the preferable dosage regimen in the treatment of elderly insulin-independent diabetics of moderate degree."1.26Diurnal pattern of plasma insulin and blood glucose during glibenclamide and glipizide therapy in elderly diabetics. ( Groop, L; Harno, K, 1980)
" Food intake did not influence the peak concentration, the elimination half-life or the bioavailability of the drug."1.26Influence of food intake on the absorption and effect of glipizide in diabetics and in healthy subjects. ( Melander, A; Sartor, G; Scherstén, B; Wåhlin-Boll, E, 1980)
"Ten Type 2 diabetics were examined during long-term treatment, at two dosage levels, with chlorpropamide once daily and glipizide t."1.26Impaired effect of sulfonylurea following increased dosage. ( Melander, A; Sartor, G; Scherstén, B; Wåhlin-Boll, E, 1982)
"Glipizide did not produce glucose variations in either test but did result in a significant decrease, in the first test only, in mean plasma baseline levels of lactate, which were higher than normal in these patients."1.26Plasma levels of glucose and lactate after intravenous glipizide administration in some insulin-dependent diabetics. Therapeutic effects of an associated glipizide-insulin treatment. ( Boni, C; Buzzigoli, G; Giampietro, O; Navalesi, R, 1979)

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-199050 (65.79)18.7374
1990's8 (10.53)18.2507
2000's12 (15.79)29.6817
2010's6 (7.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hung, AM1
Siew, ED1
Wilson, OD1
Perkins, AM1
Greevy, RA1
Horner, J1
Abdel-Kader, K1
Parr, SK1
Roumie, CL1
Griffin, MR1
Ikizler, TA1
Speroff, T1
Matheny, ME1
Cordiner, RLM1
Pearson, ER1
Tan, A1
Holmes, HM1
Kuo, YF1
Raji, MA1
Goodwin, JS1
Adeshara, K1
Tupe, R1
Fritsche, R1
Simova-Curd, S1
Clauss, M1
Hatt, JM1
Andersson, C1
Gislason, GH1
Jørgensen, CH1
Hansen, PR1
Vaag, A1
Sørensen, R1
Mérie, C1
Olesen, JB1
Weeke, P1
Schmiegelow, M1
Norgaard, ML1
Køber, L1
Torp-Pedersen, C1
Skoff, RA1
Waterbury, NV1
Shaw, RF1
Egge, JA1
Cantrell, M1
Carroll, MF1
Izard, A1
Riboni, K1
Burge, MR1
Schade, DS1
Bleskestad, IH1
Birkeland, KI1
Ilario, MJ1
Turyan, HV1
Axiotis, CA1
Aronson, D1
Mittleman, MA1
Burger, AJ1
Knudsen, LL1
Ouyang, D1
Nie, S1
Li, W1
Guo, H1
Liu, H1
Pan, W1
Mutalik, S1
Udupa, N1
Kumar, S1
Agarwal, S1
Subramanian, G1
Ranjith, AK1
Almér, LO2
Scheen, AJ1
de la Torre, D1
Luyckx, AS2
Lefèbvre, PJ2
Huupponen, R1
Seppälä, P1
Iisalo, E1
Greenfield, MS2
Doberne, L2
Rosenthal, M2
Schulz, B1
Widstrom, A1
Reaven, GM2
Paisey, RB1
Harkness, J1
Hartog, M1
Chadwick, T1
Sartor, G4
Melander, A5
Scherstén, B4
Wåhlin-Boll, E4
Groop, L3
Harno, K1
Fineberg, SE1
Schneider, SH1
Feinglos, MN5
Lebovitz, HE3
Tornvall, G1
Allgén, LG1
Ostman, J1
Christenson, I1
Jansson, B1
Weiner, L1
Pedrazzi, F1
Bommartini, F1
Freddo, J1
Emanueli, A1
Johansson, E1
Tötterman, KJ1
Vreman, HJ1
Remy, C1
Schoos, R1
Luyckx, A1
Lefèbvre, P1
Kuhn, CM1
Surwit, RS1
Miller, JL1
Salman, K1
Shulman, LH1
Rose, LI1
Chidester, PD1
Connito, DJ1
Ogonowski, J1
Riddle, MC1
McDaniel, PA1
Tive, LA1
Cleveland, JC1
Meldrum, DR1
Cain, BS1
Banerjee, A1
Harken, AH1
Sagedal, S1
Asberg, A1
Hartmann, A1
Bergan, S1
Berg, KJ1
Elliott, DA1
Nelson, RW1
Reusch, CE1
Feldman, EC1
Neal, LA1
Sharma, A1
Kharb, S1
Chugh, SN1
Kakkar, R1
Singh, GP1
Gokcel, A1
Karakose, H1
Ertorer, EM1
Tanaci, N1
Tutuncu, NB1
Guvener, N1
Martin, G1
Rand, J1
Manohar, V1
Talpur, NA1
Echard, BW1
Lieberman, S1
Preuss, HG1
Greenwood, RH1
Mahler, RF1
Hales, CN1
Blohmé, G1
Waldenström, J1
Guirgis, FK1
Ghanem, MH1
Abdel-Hay, MM1
Codaccioni, JL1
Fontaine, G1
King, JB1
Kalk, WJ1
Vinik, AI1
Jackson, WP1
Bracher, M1
Jacobs, P1
Lecomte, MJ1
Fowler, LK1
Klaassen, CH1
Brogden, RN1
Heel, RC1
Pakes, GE1
Speight, TM1
Avery, GS1
Giampietro, O1
Navalesi, R1
Buzzigoli, G1
Boni, C1
Jhran, W1
Aman, M1
Jawad, F1
Sultana, S1
Nanji, R1
Lebovitz, H1
Norris, E1
Dowey, KE1
Grant, AP1
Hayes, JR1
Bandisode, MS1
Boshell, BR1
Azzopardi, J1
Campbell, IW1
Clarke, BF1
Duncan, LJ1
Brunová, E1
Bucholtz, HK1
Lebovitz, FL1
Nowotna-Walcowa, R1
Szajewski, JM1
Walc, J1
Di Maria, L1
Pini, LA1
Prampolini, ML1
Deuil, R1
Cochet, B1
Balant, L1
Rilliet, B1
Zahnd, G1
El Saadani, AM1
Gaber, A1
Patsch, W1
Sailer, S1
Braunsteiner, H1
Salo, S1
Lin, JD1
Huang, MJ1
Huang, BY1
Huang, HS1
Ferlito, S1
Lunetta, M1
Mangiagli, P1
Tranchida, ML1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Retrobulbar Methylprednisolone as Adjunctive Treatment in Optic Neuritis. Randomized Controlled Trial.[NCT04942002]Phase 2/Phase 350 participants (Anticipated)Interventional2021-06-15Recruiting
QT Interval Abnormalities in Sulfonylurea Treated Type 2 Diabetes: Relationship to Treatment Induced Hypoglycaemia and Glycaemic Variability Determined by Simultaneous Ambulatory Monitoring[NCT02298803]30 participants (Actual)Interventional2015-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Pearson's Correlation Coefficient of Delta QTc and a Measure of Glucose Variability, MAGE (Mean Amplitude of Glycemic Excursion).

MAGE, a commonly used index of glucose variability, was calculated using data obtained during continuous glucose monitoring. Analysis of correlation between MAGE and delta QTc was undertaken. Please note delta QTc represents the difference between average QTc length during hypoglycemia and average QTc length during normoglycemia. (NCT02298803)
Timeframe: Nocturnal time period (2300-0700) during the 48 hours of Holter monitoring

InterventionCorrelation coefficient (Number)
Hypoglycemia Group0.09

Change in Corrected QT Interval During Day Time Hypoglycaemia

The day time period for the study spanned from 7 am in the morning until 11 pm in the evening on two consecutive days. The change in the corrected QT interval during day time hypoglycemia was determined by calculating the difference between the average QTc interval length during periods of hypoglycemia (blood glucose level <3.5 mmol/L) and the average QTc interval length during periods of normoglycemia (blood glucose level >3.5 mmol/L) for the day time period. The average QTc interval was calculated using an individually optimised correction formula. If the result of average QTc (hypoglycemia) - average QTc (normoglycemia) was positive, the participant experienced QTc prolongation during hypoglycemia. If the result of average QTc (hypoglycemia) - average QTc (normoglycemia) was negative, the participant experienced QTc shortening during hypoglycemia. (NCT02298803)
Timeframe: Day time period (0700-2300) during the 48 hours of Holter monitoring

InterventionParticipants (Count of Participants)
Experienced QTc prolongation during hypoglycemiaExperienced QTc shortening during hypoglycemia
Hypoglycemia Group21

deltaQTc

deltaQTc is the difference in QTc observed during periods of hypoglycemia and periods of normoglycemia (for those participants who experienced nocturnal hypoglycemia) (NCT02298803)
Timeframe: Nocturnal time period (2300-0700) during the 48 hours of Holter monitoring

Interventionmilliseconds (Number)
Participant 1Participant 4Participant 5Participant 10Participant 15Participant 16Participant 19Participant 24
Hypoglycemia Group104-2-6-4-1-815

Mean Amplitude of Glycemic Excursion (MAGE)

The MAGE results (in mmol/L) for the eight participants who experienced nocturnal hypoglycemia are included in the table below. (NCT02298803)
Timeframe: 48 hours of continuous glucose monitoring

Interventionmmol/L (Number)
Participant 1Participant 4Participant 5Participant 10Participant 15Participant 16Participant 19Participant 24
Hypoglycemia Group3.94.73.03.91.83.65.74.3

Reviews

5 reviews available for glipizide and Diabetes Mellitus

ArticleYear
Reflections on the sulphonylurea story: A drug class at risk of extinction or a drug class worth reviving?
    Diabetes, obesity & metabolism, 2019, Volume: 21, Issue:4

    Topics: Diabetes Mellitus; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Dose-Response Rela

2019
[Glipizide--a short-acting sulphonylurea derivative].
    Przeglad lekarski, 1996, Volume: 53, Issue:9

    Topics: Aged; Diabetes Mellitus; Drug Therapy, Combination; Glipizide; Humans; Hypoglycemic Agents; Insulin;

1996
Current understanding of feline diabetes: part 2, treatment.
    Journal of feline medicine and surgery, 2000, Volume: 2, Issue:1

    Topics: Animals; Blood Glucose; Body Weight; Cat Diseases; Cats; Diabetes Complications; Diabetes Mellitus;

2000
Glipizide: a review of its pharmacological properties and therapeutic use.
    Drugs, 1979, Volume: 18, Issue:5

    Topics: Animals; Diabetes Mellitus; Fatty Acids; Glipizide; Glucagon; Humans; Hypoglycemic Agents; Kinetics;

1979
[Glipizide a new oral antidiabetic agent (comprehensive review)].
    Vnitrni lekarstvi, 1976, Volume: 22, Issue:6

    Topics: Animals; Blood Glucose; Chemical Phenomena; Chemistry; Diabetes Mellitus; Dogs; Drug Evaluation; Gli

1976

Trials

21 trials available for glipizide and Diabetes Mellitus

ArticleYear
Control of postprandial hyperglycemia: optimal use of short-acting insulin secretagogues.
    Diabetes care, 2002, Volume: 25, Issue:12

    Topics: C-Peptide; Cross-Over Studies; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Glipizide; Huma

2002
Effects of sulfonylurea hypoglycemic agents and adenosine triphosphate dependent potassium channel antagonists on ventricular arrhythmias in patients with decompensated heart failure.
    Pacing and clinical electrophysiology : PACE, 2003, Volume: 26, Issue:5

    Topics: Aged; Analysis of Variance; Anti-Arrhythmia Agents; Chi-Square Distribution; Diabetes Complications;

2003
Glipizide versus tolbutamide, an open trial. Effects on insulin secretory patterns and glucose concentrations.
    Diabetologia, 1980, Volume: 18, Issue:1

    Topics: Aged; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Fasting; Female; Glipizide; Glucos

1980
The antidiabetic effect and pharmacokinetic properties of glipizide. Comparison of a single dose with divided dose regime.
    Acta medica Scandinavica, 1981, Volume: 210, Issue:3

    Topics: Aged; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Dose-Response Relationship, Drug;

1981
A study of the possible interaction of indoprofen with hypoglycemic sulfonylureas in diabetic patients.
    European journal of rheumatology and inflammation, 1981, Volume: 4, Issue:1

    Topics: Aged; Blood Glucose; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Double-Bli

1981
Propranolol does not inhibit sulphonylurea-stimulated insulin secretion in patients with non-insulin dependent diabetes mellitus.
    Acta endocrinologica, 1982, Volume: 100, Issue:3

    Topics: Aged; Blood Glucose; C-Peptide; Clinical Trials as Topic; Diabetes Mellitus; Double-Blind Method; Fe

1982
Glipizide-GITS does not increase the hypoglycemic effect of mild exercise during fasting in NIDDM.
    Diabetes care, 1997, Volume: 20, Issue:6

    Topics: Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Double-Blind Me

1997
Evaluation of oxidative stress before and after control of glycemia and after vitamin E supplementation in diabetic patients.
    Metabolism: clinical and experimental, 2000, Volume: 49, Issue:2

    Topics: Adult; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Femal

2000
Effects of sibutramine in obese female subjects with type 2 diabetes and poor blood glucose control.
    Diabetes care, 2001, Volume: 24, Issue:11

    Topics: Appetite Depressants; Blood Glucose; Cholesterol; Cyclobutanes; Diabetes Mellitus; Double-Blind Meth

2001
Glibenclamide and glipizide in maturity onset diabetes. A double-blind cross-over study.
    Acta medica Scandinavica, 1979, Volume: 206, Issue:4

    Topics: Aged; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Double-Blind Method; Female; Glipi

1979
An evaluation of the effects of some sulphonylureas on platelet function.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1977, Jan-29, Volume: 51, Issue:5

    Topics: Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Female; Gliclazide; Glipizide; Humans; L

1977
Plasma glucagon and clinical control of maturity-onset type diabetes. Effects of diet, placebo and glipizide.
    Diabete & metabolisme, 1977, Volume: 3, Issue:4

    Topics: Adult; Aged; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Fatty Acids, Nonesterified;

1977
Effects of glipizide and food intake on the blood levels of glucose and insulin in diabetic patients.
    Acta medica Scandinavica, 1978, Volume: 203, Issue:3

    Topics: Adult; Aged; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Drug Evaluation; Female; Fo

1978
Glipizide in the treatment of maturity-onset diabetes: a multi-centre, out-patient study.
    Current medical research and opinion, 1978, Volume: 5, Issue:5

    Topics: Adult; Aged; Blood Glucose; Body Weight; Clinical Trials as Topic; Diabetes Mellitus; Female; Glipiz

1978
Glipizide ('Glibenese') in maturity-onset diabetes mellitus.
    Current medical research and opinion, 1979, Volume: 6, Issue:1

    Topics: Aged; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Female; Glipizide; Humans; Male; M

1979
[Clinical experience with Glipizide in a diabetes outpatient department].
    MMW, Munchener medizinische Wochenschrift, 1977, Jul-22, Volume: 119, Issue:29-30

    Topics: Clinical Trials as Topic; Diabetes Mellitus; Drug Evaluation; Female; Glipizide; Humans; Male; Sulfo

1977
Clinical trial with glipizide in uncomplicated maturity onset diabetes mellitus.
    JPMA. The Journal of the Pakistan Medical Association, 1977, Volume: 27, Issue:3

    Topics: Adult; Aged; Clinical Trials as Topic; Diabetes Mellitus; Drug Evaluation; Female; Glipizide; Humans

1977
Clinical evaluation of a new sulfonylurea in maturity onset diabetes - glipizide (K-4024).
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1976, Volume: 8, Issue:2

    Topics: Adult; Aged; Chlorpropamide; Clinical Trials as Topic; Diabetes Mellitus; Dose-Response Relationship

1976
[Duration of effective hypoglycaemic action of glipizide given once daily (author's transl)].
    Medizinische Klinik, 1975, Jul-11, Volume: 70, Issue:28-29

    Topics: Administration, Oral; Aged; Biological Availability; Blood Glucose; Circadian Rhythm; Clinical Trial

1975
[Glipizide: a 2d generation sulfonamide and new antidiabetic].
    La Nouvelle presse medicale, 1975, Feb-15, Volume: 4, Issue:7

    Topics: Adult; Aged; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Drug Evaluation; Female; Fo

1975
Combination of two sulfonylureas. Does it make sense.
    Diabetes care, 1988, Volume: 11, Issue:9

    Topics: Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Diabetes Mellitus, Type 2; Drug Therapy,

1988

Other Studies

50 other studies available for glipizide and Diabetes Mellitus

ArticleYear
Risk of Hypoglycemia Following Hospital Discharge in Patients With Diabetes and Acute Kidney Injury.
    Diabetes care, 2018, Volume: 41, Issue:3

    Topics: Acute Kidney Injury; Adult; Aged; Blood Glucose; Diabetes Mellitus; Diabetic Nephropathies; Female;

2018
Coadministration of co-trimoxazole with sulfonylureas: hypoglycemia events and pattern of use.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2015, Volume: 70, Issue:2

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Cohort Studies; Diabetes Mellitus; Drug Interactions

2015
Antiglycation and cell protective actions of metformin and glipizide in erythrocytes and monocytes.
    Molecular biology reports, 2016, Volume: 43, Issue:3

    Topics: Antioxidants; Cytoprotection; Diabetes Mellitus; Erythrocytes; Glipizide; Glycated Serum Albumin; Gl

2016
Hyperthyroidism in connection with suspected diabetes mellitus in a chinchilla (Chinchilla laniger).
    The Veterinary record, 2008, Oct-11, Volume: 163, Issue:15

    Topics: Animals; Antithyroid Agents; Chinchilla; Diabetes Complications; Diabetes Mellitus; Diagnosis, Diffe

2008
Comparable long-term mortality risk associated with individual sulfonylureas in diabetes patients with heart failure.
    Diabetes research and clinical practice, 2011, Volume: 94, Issue:1

    Topics: Aged; Aged, 80 and over; Diabetes Mellitus; Female; Glipizide; Glyburide; Heart Failure; Humans; Hyp

2011
Glycemic control and hypoglycemia in Veterans Health Administration patients converted from glyburide to glipizide.
    Journal of managed care pharmacy : JMCP, 2011, Volume: 17, Issue:9

    Topics: Aged; Blood Glucose; Creatinine; Diabetes Mellitus; Female; Glipizide; Glyburide; Glycated Hemoglobi

2011
[Differences between oral antidiabetics].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2003, Mar-20, Volume: 123, Issue:6

    Topics: Administration, Oral; Carbamates; Cyclohexanes; Diabetes Mellitus; Glipizide; Humans; Hypoglycemic A

2003
Glipizide treatment with short-term alcohol abuse resulting in subfulminant hepatic failure.
    Virchows Archiv : an international journal of pathology, 2003, Volume: 443, Issue:1

    Topics: Alcoholism; Diabetes Complications; Diabetes Mellitus; Fatal Outcome; Female; Glipizide; Humans; Hyp

2003
Retrobulbar injection of methylprednisolone in diffuse diabetic macular edema.
    Retina (Philadelphia, Pa.), 2004, Volume: 24, Issue:6

    Topics: Administration, Oral; Aged; Aged, 80 and over; Diabetes Mellitus; Diabetic Retinopathy; Glipizide; G

2004
Design and evaluation of compound metformin/glipizide elementary osmotic pump tablets.
    The Journal of pharmacy and pharmacology, 2005, Volume: 57, Issue:7

    Topics: Delayed-Action Preparations; Diabetes Mellitus; Drug Design; Glipizide; Humans; Hypoglycemic Agents;

2005
Glipizide matrix transdermal systems for diabetes mellitus: preparation, in vitro and preclinical studies.
    Life sciences, 2006, Sep-13, Volume: 79, Issue:16

    Topics: Acrylic Resins; Administration, Cutaneous; Animals; Cellulose; Diabetes Mellitus; Drug Delivery Syst

2006
Vascular fibrinolytic activity in long term treatment with second generation sulfonylurea compounds.
    Acta endocrinologica. Supplementum, 1980, Volume: 239

    Topics: alpha-Macroglobulins; Blood Vessels; Chlorpropamide; Diabetes Mellitus; Endothelium; Fibrinolysis; G

1980
[Metabolic and hormonal response to a standardized breakfast in type 2 diabetes. Effect of glipizide].
    Revue medicale de Liege, 1983, Mar-15, Volume: 38, Issue:6

    Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus; Female; Food; Glipizide; Humans; Insulin; Male; Middl

1983
Glyburide and glipizide.
    The Medical letter on drugs and therapeutics, 1984, Aug-31, Volume: 26, Issue:669

    Topics: Diabetes Mellitus; Glipizide; Glyburide; Humans; Sulfonylurea Compounds

1984
Glipizide pharmacokinetics and response in diabetics.
    International journal of clinical pharmacology, therapy, and toxicology, 1982, Volume: 20, Issue:9

    Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus; Female; Glipizide; Humans; Insulin; Kinetics; Male; M

1982
Effect of sulfonylurea treatment on in vivo insulin secretion and action in patients with non-insulin-dependent diabetes mellitus.
    Diabetes, 1982, Volume: 31, Issue:4 Pt 1

    Topics: Aged; Blood Glucose; Diabetes Mellitus; Female; Glipizide; Humans; Insulin; Insulin Resistance; Insu

1982
The effect of improvement in diabetic control on plasma and whole blood viscosity.
    Diabetologia, 1980, Volume: 19, Issue:4

    Topics: Adolescent; Adult; Blood; Blood Glucose; Diabetes Mellitus; Female; Glipizide; Glyburide; Hemoglobin

1980
Kinetics-effect relations of glipizide and other sulfonylureas.
    Acta endocrinologica. Supplementum, 1980, Volume: 239

    Topics: Blood Glucose; Chlorpropamide; Diabetes Mellitus; Dose-Response Relationship, Drug; Fasting; Feeding

1980
Diurnal pattern of plasma insulin and blood glucose during glibenclamide and glipizide therapy in elderly diabetics.
    Acta endocrinologica. Supplementum, 1980, Volume: 239

    Topics: Aged; Blood Glucose; Circadian Rhythm; Diabetes Mellitus; Female; Glipizide; Glyburide; Humans; Insu

1980
Sulfonylurea treatment of insulin-independent diabetes mellitus.
    Metabolism: clinical and experimental, 1980, Volume: 29, Issue:5

    Topics: Blood Glucose; Body Weight; Diabetes Mellitus; Diet, Diabetic; Glipizide; Humans; Hypoglycemic Agent

1980
Acute effects of acetylsalicylic acid on blood glucose and insulin in non-insulin dependent diabetes.
    Acta endocrinologica. Supplementum, 1980, Volume: 239

    Topics: Aspirin; Blood Glucose; Diabetes Mellitus; Female; Glipizide; Humans; Insulin; Male

1980
Influence of food intake on the absorption and effect of glipizide in diabetics and in healthy subjects.
    European journal of clinical pharmacology, 1980, Volume: 18, Issue:3

    Topics: Adult; Blood Glucose; Diabetes Mellitus; Food; Glipizide; Humans; Insulin; Intestinal Absorption; Ki

1980
Impaired effect of sulfonylurea following increased dosage.
    European journal of clinical pharmacology, 1982, Volume: 22, Issue:1

    Topics: Aged; Blood Glucose; Body Weight; Chlorpropamide; Diabetes Mellitus; Dose-Response Relationship, Dru

1982
Influence of sulfonylureas on the secretion, disposal and effect of insulin.
    European journal of clinical pharmacology, 1982, Volume: 22, Issue:1

    Topics: Aged; Blood Glucose; C-Peptide; Chlorpropamide; Diabetes Mellitus; Female; Glipizide; Half-Life; Hum

1982
Lipid metabolism in non-insulin-dependent diabetes mellitus: effect of glipizide therapy.
    Archives of internal medicine, 1982, Volume: 142, Issue:8

    Topics: Aged; Cholesterol; Coronary Disease; Diabetes Mellitus; Female; Glipizide; Humans; Lipid Metabolism;

1982
[Determination of hemoglobin A1c for the evaluation of metabolic equilibrium in patients with non-insulin-dependent diabetes treated with glipizide].
    Revue medicale de Liege, 1980, May-15, Volume: 35, Issue:10

    Topics: Blood Glucose; Diabetes Mellitus; Glipizide; Glycosides; Hemoglobin A; Humans; Sulfonylurea Compound

1980
Glipizide stimulates sympathetic outflow in diabetes-prone mice.
    Life sciences, 1995, Volume: 56, Issue:9

    Topics: Animals; Diabetes Mellitus; Disease Susceptibility; Glipizide; Liver; Methyltyrosines; Mice; Mice, I

1995
Bedtime insulin added to daytime sulfonylureas improves glycemic control in uncontrolled type II diabetes.
    Clinical pharmacology and therapeutics, 1993, Volume: 53, Issue:3

    Topics: Adult; Aged; Diabetes Mellitus; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Glipizide; Gly

1993
Interaction between glipizide and cyclosporine: report of two cases.
    Transplantation proceedings, 1993, Volume: 25, Issue:2

    Topics: Adult; Creatinine; Cyclosporine; Diabetes Mellitus; Drug Interactions; Glipizide; Glomerulonephritis

1993
Oral sulfonylurea hypoglycemic agents prevent ischemic preconditioning in human myocardium. Two paradoxes revisited.
    Circulation, 1997, Jul-01, Volume: 96, Issue:1

    Topics: Administration, Oral; Aged; Diabetes Mellitus; Female; Glipizide; Glyburide; Heart Atria; Humans; Hy

1997
Glipizide treatment of post-transplant diabetes does not interfere with cyclosporine pharmacokinetics in renal allograft recipients.
    Clinical transplantation, 1998, Volume: 12, Issue:6

    Topics: Adult; Aged; Cyclosporine; Diabetes Mellitus; Drug Interactions; Female; Glipizide; Humans; Hypoglyc

1998
Comparison of serum fructosamine and blood glycosylated hemoglobin concentrations for assessment of glycemic control in cats with diabetes mellitus.
    Journal of the American Veterinary Medical Association, 1999, Jun-15, Volume: 214, Issue:12

    Topics: Animals; Blood Glucose; Cat Diseases; Cats; Cohort Studies; Diabetes Mellitus; Fructosamine; Glipizi

1999
Effects of a water-soluble extract of maitake mushroom on circulating glucose/insulin concentrations in KK mice.
    Diabetes, obesity & metabolism, 2002, Volume: 4, Issue:1

    Topics: Agaricales; Animals; Blood Glucose; Diabetes Mellitus; Glipizide; Glucans; Hypoglycemic Agents; Insu

2002
Diazoxide, glipizide, and hypoglycaemia.
    Lancet (London, England), 1977, Feb-05, Volume: 1, Issue:8006

    Topics: Blood Glucose; Diabetes Mellitus; Diazoxide; Drug Antagonism; Glipizide; Humans; Hypoglycemia; Insul

1977
Comparative study of the hypoglycaemic and antilipolytic effects of four antidiabetic agents administered i.v.
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:3

    Topics: Adult; Blood Glucose; Diabetes Mellitus; Fatty Acids, Nonesterified; Female; Glipizide; Glyburide; H

1976
[Diabetes: new drugs?].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1976, May-23, Volume: 52, Issue:20

    Topics: Biguanides; Diabetes Mellitus; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Insulin; Sulfonylu

1976
Plasma levels of glucose and lactate after intravenous glipizide administration in some insulin-dependent diabetics. Therapeutic effects of an associated glipizide-insulin treatment.
    Current medical research and opinion, 1979, Volume: 6, Issue:5

    Topics: Adult; Blood Glucose; Diabetes Mellitus; Drug Therapy, Combination; Female; Glipizide; Humans; Injec

1979
Insulin resistance in patients with insulin independent diabetes mellitus: partial amelioration by the sulfonylurea glipizide.
    Advances in experimental medicine and biology, 1979, Volume: 119

    Topics: Blood Glucose; Diabetes Mellitus; Diet, Diabetic; Glipizide; Glucose; Glucose Tolerance Test; Humans

1979
Glipizide: a new second generation sulfonylurea.
    Advances in experimental medicine and biology, 1979, Volume: 119

    Topics: Blood Glucose; Diabetes Mellitus; Diet, Diabetic; Glipizide; Humans; Insulin; Sulfonylurea Compounds

1979
Glipizide evaluation after a one year trial in maturity onset diabetics.
    The Ulster medical journal, 1979, Volume: 48, Issue:1

    Topics: Aged; Diabetes Mellitus; Drug Evaluation; Glipizide; Humans; Middle Aged; Obesity; Sulfonylurea Comp

1979
Sulphonylureas increase the number of insulin receptors.
    Nature, 1978, Nov-09, Volume: 276, Issue:5684

    Topics: Animals; Diabetes Mellitus; Glipizide; Insulin; Kinetics; Male; Mice; Receptor, Insulin; Sulfonylure

1978
Potentiation of insulin action: a probable mechanism for the anti-diabetic action of sulfonylurea drugs.
    The Journal of clinical endocrinology and metabolism, 1977, Volume: 45, Issue:3

    Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus; Drug Synergism; Female; Glipizide; Humans; Insulin; M

1977
[Evaluation of glipizide].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1976, Sep-15, Volume: 29, Issue:18

    Topics: Diabetes Mellitus; Drug Evaluation; Glipizide; Humans; Intestinal Absorption; Sulfonylurea Compounds

1976
[Glipizide-phenformin combination in the treatment of diabetes mellitus].
    La Clinica terapeutica, 1976, May-31, Volume: 77, Issue:4

    Topics: Aged; Diabetes Mellitus; Drug Combinations; Drug Evaluation; Female; Glipizide; Humans; Male; Middle

1976
[A clinical study of a new sulfonylures hypoglycemic agent: glipizide (glibenese)(author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1975, May-06, Volume: 64, Issue:18

    Topics: Acetone; Aged; Blood Glucose; Chemical Phenomena; Chemistry; Delayed-Action Preparations; Diabetes M

1975
Glipizide - another oral hypoglycaemic drug.
    Drug and therapeutics bulletin, 1975, Oct-10, Volume: 13, Issue:21

    Topics: Diabetes Mellitus; Glipizide; Humans; Sulfonylurea Compounds

1975
Glipizide--a new oral antidiabetic.
    The Journal of the Egyptian Medical Association, 1975, Volume: 58, Issue:11-12

    Topics: Administration, Oral; Adult; Diabetes Mellitus; Female; Glipizide; Humans; Male; Sulfonylurea Compou

1975
[The effect of Glipizide on the blood glucose and insulin in non-ketotic diabetes mellitus (author's transl)].
    Wiener klinische Wochenschrift, 1976, Jan-23, Volume: 88, Issue:2

    Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus; Glipizide; Humans; Hyperlipidemias; Insulin; Insulin

1976
[Clinical evaluation of the oral hypoglycemic agent glipizide].
    Changgeng yi xue za zhi, 1986, Sep-20, Volume: 9, Issue:3

    Topics: Adult; Aged; Diabetes Mellitus; Female; Glipizide; Humans; Hypoglycemic Agents; Male; Middle Aged; S

1986
[Effects of treatment with glipizide-metformin on the behavior of blood sugar, insulin and lipids after intravenous administration of glucose in diabetic subjects].
    Giornale di clinica medica, 1974, Volume: 55, Issue:11

    Topics: Adult; Blood Glucose; Diabetes Mellitus; Female; Glipizide; Glucose; Humans; Insulin; Lipids; Male;

1974