Page last updated: 2024-10-28

glipizide and Alloxan Diabetes

glipizide has been researched along with Alloxan Diabetes in 14 studies

Glipizide: An oral hypoglycemic agent which is rapidly absorbed and completely metabolized.
glipizide : An N-sulfonylurea that is glyburide in which the (5-chloro-2-methoxybenzoyl group is replaced by a (5-methylpyrazin-2-yl)carbonyl group. An oral hypoglycemic agent, it is used in the treatment of type 2 diabetes mellitus.

Research Excerpts

ExcerptRelevanceReference
") ethanolic extract (APE) and andrographolide (AND) (a potent CYP2C9 inducer/inhibitor) can alter the pharmacokinetic parameters of glipizide (GLZ)."1.72Pharmacokinetic Herb-Drug Interactions of Glipizide with ( Amalia Prihati, D; Lukitaningsih, E; Nugroho, AE; Nurrochmad, A; Puspitasari, I; Sundhani, E, 2022)
" AZI (500 mg/kg) pretreatment significantly decreased AUC and increased Tmax to 8 h."1.51Effect of Aqueous Extract of Azadirachta indica Leaves on Pharmacokineics and Pharmacodynamics of Glipizide. ( Ali, M; Chaudhari, S; Zambad, S, 2019)
" Aqueous extract of Annona squamosa was administered orally at 350 mg/kg body weight alone and in combination with reduced and reducing dose combinations of Glipizide."1.39Polypharmacy (herbal and synthetic drug combination): a novel approach in the treatment of type-2 diabetes and its complications in rats. ( Afzal, M; Ahamd, I; Ahmad, S; Ahmed, Z; Ali, B; Anwar, F; Kaur, R; Kazmi, I, 2013)
" Oral therapy with glipizide comprises problems of bioavailability fluctuations and may be associated with severe hypoglycaemia and gastric disturbances."1.33A transdermal delivery system for glipizide. ( Ammar, HO; El-Nahhas, SA; Elmotasem, H; Ghorab, M; Salama, HA, 2006)
"Glipizide therapy also was ineffective in improving plasma insulin levels, which were significantly depressed in the diabetic group."1.29Effects of chronic glipizide treatment on the NIDD heart. ( Schaffer, SW; Warner, BA; Wilson, GL, 1993)
"Glipizide-treated mice improved their OGTT."1.28Diabetic microangiopathy in KK mice. VI. Effect of glycemic control on renal glycoprotein metabolism and established glomerulosclerosis. ( Camerini-Davalos, RA; Khan, MY; Reddi, AS; Reddy, PR; Velasco, CA, 1990)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's3 (21.43)18.2507
2000's4 (28.57)29.6817
2010's5 (35.71)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Sundhani, E1
Nugroho, AE1
Nurrochmad, A1
Puspitasari, I1
Amalia Prihati, D1
Lukitaningsih, E1
Ray, S1
Bera, M1
Bhattacharyya, UK1
Das, S1
Seth, S1
Pal, PK1
Aziz, A1
Chaudhari, S1
Zambad, S1
Ali, M1
Whittam, AJ1
Maan, ZN1
Duscher, D1
Barrera, JA1
Hu, MS1
Fischer, LH1
Khong, S1
Kwon, SH1
Wong, VW1
Walmsley, GG1
Giacco, F1
Januszyk, M1
Brownlee, M1
Longaker, MT1
Gurtner, GC1
Mu, J1
Petrov, A1
Eiermann, GJ1
Woods, J1
Zhou, YP1
Li, Z1
Zycband, E1
Feng, Y1
Zhu, L1
Roy, RS1
Howard, AD1
Li, C1
Thornberry, NA1
Zhang, BB1
Kumar, S1
Kunaparaju, N1
Zito, SW1
Barletta, MA1
Kaur, R1
Afzal, M1
Kazmi, I1
Ahamd, I1
Ahmed, Z1
Ali, B1
Ahmad, S1
Anwar, F1
Srinivasan, K1
Viswanad, B1
Asrat, L1
Kaul, CL1
Ramarao, P1
Ammar, HO1
Salama, HA1
Ghorab, M1
El-Nahhas, SA1
Elmotasem, H1
Li, W1
Dai, RJ1
Yu, YH1
Li, L1
Wu, CM1
Luan, WW1
Meng, WW1
Zhang, XS1
Deng, YL1
Schaffer, SW1
Warner, BA1
Wilson, GL1
Tüzün, S1
Girgin, FK1
Sözmen, EY1
Menteş, G1
Ersöz, B1
Reddi, AS2
Velasco, CA2
Reddy, PR1
Khan, MY2
Camerini-Davalos, RA2
Bloodworth, JM1

Other Studies

14 other studies available for glipizide and Alloxan Diabetes

ArticleYear
Pharmacokinetic Herb-Drug Interactions of Glipizide with
    Molecules (Basel, Switzerland), 2022, Oct-14, Volume: 27, Issue:20

    Topics: Andrographis; Andrographis paniculata; Animals; Chromatography, High Pressure Liquid; Cytochrome P-4

2022
pH Sensitive Interpenetrating Network Bio Containers of Gum Ghatti for Sustained Release of Glipizide.
    Current drug delivery, 2019, Volume: 16, Issue:9

    Topics: Animals; Blood Glucose; Cell Survival; Cells, Cultured; Delayed-Action Preparations; Diabetes Mellit

2019
Effect of Aqueous Extract of Azadirachta indica Leaves on Pharmacokineics and Pharmacodynamics of Glipizide.
    Drug metabolism letters, 2019, Volume: 13, Issue:1

    Topics: Animals; Area Under Curve; Azadirachta; Blood Glucose; Cytochrome P-450 CYP3A; Diabetes Mellitus, Ex

2019
Small molecule inhibition of dipeptidyl peptidase-4 enhances bone marrow progenitor cell function and angiogenesis in diabetic wounds.
    Translational research : the journal of laboratory and clinical medicine, 2019, Volume: 205

    Topics: Animals; Chemokine CXCL12; Diabetes Mellitus, Experimental; Dipeptidyl Peptidase 4; Dipeptidyl-Pepti

2019
Inhibition of DPP-4 with sitagliptin improves glycemic control and restores islet cell mass and function in a rodent model of type 2 diabetes.
    European journal of pharmacology, 2009, Nov-25, Volume: 623, Issue:1-3

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Fats; Di

2009
Effect of Wrightia tinctoria and Parthenocissus quinquefolia on blood glucose and insulin levels in the Zucker diabetic rat model.
    Journal of complementary & integrative medicine, 2011, Volume: 8

    Topics: Animals; Apocynaceae; Diabetes Mellitus, Experimental; Enzyme-Linked Immunosorbent Assay; Female; Gl

2011
Polypharmacy (herbal and synthetic drug combination): a novel approach in the treatment of type-2 diabetes and its complications in rats.
    Journal of natural medicines, 2013, Volume: 67, Issue:3

    Topics: Administration, Oral; Animals; Annona; Behavior, Animal; Blood Glucose; Body Weight; Catalase; Diabe

2013
Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screening.
    Pharmacological research, 2005, Volume: 52, Issue:4

    Topics: Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Dietary Fats; Glipizide; Gluco

2005
A transdermal delivery system for glipizide.
    Current drug delivery, 2006, Volume: 3, Issue:3

    Topics: Acrylic Resins; Adjuvants, Pharmaceutic; Administration, Cutaneous; Animals; Biological Availability

2006
Antihyperglycemic effect of Cephalotaxus sinensis leaves and GLUT-4 translocation facilitating activity of its flavonoid constituents.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:6

    Topics: Adipocytes; Animals; Blood Glucose; Blotting, Western; Carboxymethylcellulose Sodium; Cell Membrane;

2007
Effects of chronic glipizide treatment on the NIDD heart.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1993, Volume: 25, Issue:7

    Topics: Animals; Animals, Newborn; Blood Glucose; Cardiac Output, Low; Diabetes Mellitus, Experimental; Diab

1993
Antioxidant status in experimental type 2 diabetes mellitus: effects of glibenclamide and glipizide on various rat tissues.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1999, Volume: 51, Issue:4-5

    Topics: Animals; Antioxidants; Brain; Catalase; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2;

1999
Diabetic microangiopathy in KK mice. VI. Effect of glycemic control on renal glycoprotein metabolism and established glomerulosclerosis.
    Experimental and molecular pathology, 1990, Volume: 53, Issue:2

    Topics: Acetylglucosaminidase; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Angiopathie

1990
Kidney disease in KK mice: effect of glipizide.
    Advances in experimental medicine and biology, 1988, Volume: 246

    Topics: Animals; Basement Membrane; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies;

1988