Page last updated: 2024-08-17

gliotoxin and Necrosis

gliotoxin has been researched along with Necrosis in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's7 (77.78)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brenner, DA; Kweon, YO; Lemasters, JJ; Paik, YH; Qian, T; Schnabl, B1
Cameron, GA; Elrick, LJ; Halestrap, AP; Haughton, EL; Hawksworth, GM; Leel, V; Marek, CJ; Orr, JG; Trim, JE; Wright, MC1
Bols, NC; DeWitte-Orr, SJ1
Anselmi, K; Gandhi, CR; Kamath, R; Nalesnik, M; Stolz, DB; Watkins, SC1
Aringer, M; Ekhart, H; Feierl, E; Karonitsch, T; Smolen, JS; Steiner, CW; Stummvoll, GH1
Bauerschmidt, S; Draaisma, AL; Elferink, MG; Groothuis, GM; Merema, MT; Olinga, P; Polman, J; Schoonen, WG1
Sjaarda, A; Waring, P1
Beaver, J; Hurne, A; Lambert, D; Sjaarda, A; Waring, P1
Chai, CL; Hurne, AM; Moerman, K; Waring, P1

Trials

1 trial(s) available for gliotoxin and Necrosis

ArticleYear
Engulfed cell remnants, and not cells undergoing apoptosis, constitute the LE-cell phenomenon.
    Autoimmunity, 2007, Volume: 40, Issue:4

    Topics: Antibodies, Antinuclear; Apoptosis; Dactinomycin; Female; Gliotoxin; Histones; Hot Temperature; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Male; Necrosis; Nucleic Acid Synthesis Inhibitors

2007

Other Studies

8 other study(ies) available for gliotoxin and Necrosis

ArticleYear
Gliotoxin-mediated apoptosis of activated human hepatic stellate cells.
    Journal of hepatology, 2003, Volume: 39, Issue:1

    Topics: Adenosine Triphosphate; Annexin A5; Apoptosis; Caspase 3; Caspases; Cell Line, Transformed; Cyclosporine; Cytochromes c; Cytosol; Dopamine Antagonists; Gliotoxin; Humans; Immunosuppressive Agents; Liver; Liver Cirrhosis; Mitochondria; Necrosis; NF-kappa B; Oxidative Stress; Protein Binding; Reactive Oxygen Species; Trifluoperazine

2003
Mechanism of action of the antifibrogenic compound gliotoxin in rat liver cells.
    Hepatology (Baltimore, Md.), 2004, Volume: 40, Issue:1

    Topics: Animals; Antioxidants; Cells, Cultured; Dose-Response Relationship, Drug; Gliotoxin; Glutathione; Hepatocytes; Liver; Liver Cirrhosis; Male; Necrosis; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reducing Agents; Sulfhydryl Compounds

2004
Gliotoxin-induced cytotoxicity in three salmonid cell lines: cell death by apoptosis and necrosis.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2005, Volume: 141, Issue:2

    Topics: Animals; Apoptosis; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Epithelial Cells; Fibroblasts; Gliotoxin; Macrophages; Necrosis; Salmonidae

2005
Gliotoxin causes apoptosis and necrosis of rat Kupffer cells in vitro and in vivo in the absence of oxidative stress: exacerbation by caspase and serine protease inhibition.
    Journal of hepatology, 2007, Volume: 47, Issue:1

    Topics: Animals; Apoptosis; Carbon Tetrachloride; Caspase 3; Caspase Inhibitors; Cell Survival; Cytochromes c; Gliotoxin; Hepatocytes; Kupffer Cells; Liver Cirrhosis, Experimental; Mitogen-Activated Protein Kinase Kinases; Necrosis; NF-kappa B; Oxidative Stress; Phosphorylation; Protein Transport; Rats; Serine Endopeptidases; Serine Proteinase Inhibitors

2007
Microarray analysis in rat liver slices correctly predicts in vivo hepatotoxicity.
    Toxicology and applied pharmacology, 2008, Jun-15, Volume: 229, Issue:3

    Topics: Acetaminophen; Animals; Apoptosis; Carbon Tetrachloride; Down-Regulation; Fibrosis; Forecasting; Gliotoxin; Inflammation; Lipopolysaccharides; Liver; Male; Necrosis; Oligonucleotide Array Sequence Analysis; Rats; Rats, Wistar; Time Factors; Toxicity Tests; Up-Regulation

2008
Extracellular calcium is not required for gliotoxin or dexamethasone-induced DNA fragmentation: a reappraisal of the use of EGTA.
    International journal of immunopharmacology, 1995, Volume: 17, Issue:5

    Topics: Animals; Apoptosis; Calcium; Cells, Cultured; Dexamethasone; DNA; Dose-Response Relationship, Drug; Egtazic Acid; Ethidium; Flow Cytometry; Gliotoxin; Immunosuppressive Agents; Macrophages; Mice; Mice, Inbred BALB C; Necrosis; Thymus Gland; Time Factors

1995
Increased cell surface exposure of phosphatidylserine on propidium iodide negative thymocytes undergoing death by necrosis.
    Cell death and differentiation, 1999, Volume: 6, Issue:7

    Topics: Animals; Calcium; Cell Death; Cell Membrane; Dexamethasone; Disulfides; DNA Fragmentation; Gliotoxin; In Vitro Techniques; Mice; Mice, Inbred BALB C; Necrosis; Phosphatidylserines; Propidium; Pyridines; Sulfhydryl Reagents; T-Lymphocytes; Thapsigargin

1999
Influx of calcium through a redox-sensitive plasma membrane channel in thymocytes causes early necrotic cell death induced by the epipolythiodioxopiperazine toxins.
    The Journal of biological chemistry, 2002, Aug-30, Volume: 277, Issue:35

    Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channels; Cell Membrane; Cells, Cultured; Gliotoxin; Glutathione; Kinetics; Mice; Mice, Inbred BALB C; Necrosis; Oxidation-Reduction; Piperazines; T-Lymphocytes

2002