Page last updated: 2024-08-17

gliotoxin and Aspergillus Infection

gliotoxin has been researched along with Aspergillus Infection in 54 studies

Research

Studies (54)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (3.70)	18.7374
1990's	5 (9.26)	18.2507
2000's	17 (31.48)	29.6817
2010's	26 (48.15)	24.3611
2020's	4 (7.41)	2.80

Authors

Authors	Studies
Adkesson, M; Aitken-Palmer, C; Bronson, E; Cardenas, J; Chauvin, D; Cray, C; Desoubeaux, G; Govett, P; Kahl, K; Reidy, L; Seither, J; Sirpenski, G; Stadler, C; Tocidlowski, M	1
Gomez-Lopez, A; Pando Pozo, R; Rueda, C; Sanchez Gonzalez, LM	1
Choi, YH; Lee, MW; Lwin, HP; Shin, KS; Yu, JH	1
Goldman, GH; Knowles, SL; Mead, ME; Oberlies, NH; Raja, HA; Rokas, A; Silva, LP; Steenwyk, JL	1
Almeida, F; Bowyer, P; Bromley, M; Colabardini, AC; de Assis, LJ; de Castro, PA; Demasi, M; Dong, Z; Dos Santos, RAC; Doyle, S; Ferreira Filho, JA; Goldman, GH; Hernández, DCR; Loures, FV; Netto, LES; Owens, RA; Pardeshi, L; Preite, NW; Pupo, MT; Ries, LNA; Rokas, A; Silva, LP; Steenwyk, JL; Tan, K; Wong, KH	1
Kwon-Chung, KJ; Lee, CR; Lionakis, MS; Nardone, G; Rose, SR; Sugui, JA; Swamydas, M	1
Huttenlocher, A; Jain, S; Kabbage, M; Keller, NP; Knox, BP; Palmer, JM; Sekonyela, R	1
Al-Ahmad, AJ; German, N; Hossain, MA; Patel, R	1
Filler, SG; Liu, H; Mitchell, AP; Solis, NV; Woolford, C; Xu, W	1
Brakhage, AA; Chankhamjon, P; Dworschak, JD; Heinekamp, T; Hertweck, C; Scharf, DH; Scherlach, K	1
Hagiwara, D; Kamei, K; Takagi, H; Takahashi, H; Watanabe, A	1
Cavaglieri, LR; Coelho, I; Dalcero, AM; Keller, LM; Pena, GA; Rosa, CA; Soleiro, CA	1
Arena, V; Bugli, F; Cacaci, M; Caira, M; Lancellotti, S; Martini, C; Paroni Sterbini, F; Posteraro, B; Posteraro, P; Sanguinetti, M; Stigliano, E; Torelli, R	1
Campos, FR; Cerqueira, LB; de Francisco, TM; Gasparetto, JC; Pontarolo, R	1
Aoyagi, K; Bunsupa, S; Kamei, K; Muraosa, Y; Takino, M; Toyotome, T; Wang, DN; Watanabe, A; Wuren, T; Yamazaki, M	1
Bhatnagar, I; Kim, SK	1
Kamei, K; Kikuchi, K; Ochiai, E; Tamiya, H; Toyotome, T; Watanabe, A; Yaguchi, T; Yahiro, M	1
Kim, YH; Shin, KS; Yu, JH	1
Brakhage, AA; Mukherjee, PK; Scharf, DH	1
Alonso, V; Aminahuel, C; Cavaglieri, L; Dalcero, A; Díaz Vergara, L; Pereyra, C; Poloni, V	1
Abelmann, A; Bayram, Ö; Brakhage, AA; Braus, GH; Heinekamp, T; Jacobsen, ID; Jöhnk, B; Mattern, DJ; Valerius, O	1
Cervantes, RA; de Oca, VM; Gómez, GG; Ramírez, J; Segundo, C; Valdés, SE	1
Ben-Ami, R; Kontoyiannis, DP; Leventakos, K; Lewis, RE	1
Ahmad, A; Panda, BP; Puri, A	1
Carberry, S; Doyle, S; Fenelon, O; Haas, H; Jones, GW; Kavanagh, K; Nolan, A; O'Brien, J; Schrettl, M; Stephens, J	1
Ben-Ami, R; Kontoyiannis, DP; Lewis, RE	1
Boon, L; Lee, CK; Levitz, SM; Ramirez-Ortiz, ZG; Specht, CA; Wang, JP	1
Carberry, S; Doyle, S; Hammel, S; Jones, GW; Kavanagh, K; Molloy, E; O'Keeffe, G	1
Colmenarejo, C; Delgado, P; Domingo, MP; Gálvez, EM; Jarne, C; Martínez-Lostao, L; Meis, JF; Müllbacher, A; Pardo, J; Revillo, MJ; Rezusta, A; Roc, L	1
Hagleitner, M; Lass-Flörl, C; Ott, HW; Rambach, G; Speth, C; Würzner, R	1
Eshwika, A; Fallon, JP; Kavanagh, K; Kelly, J	1
Doyle, S; Fox, M; Gray, G; Kavanagh, K; Lewis, C	1
Hashimoto, Y; Higurashi, H; Kamei, K; Nishimura, K; Ochiai, E; Sekine, T; Watanabe, A	1
Doyle, S; Kavanagh, K; Messina, CG; Reeves, EP	1
Komanduri, KV; Kontoyiannis, DP; Lewis, R; Martins, SL; Orciuolo, E; St John, LS; Stanzani, M	1
Chi, J; Han, XY; Komanduri, KV; Kontoyiannis, DP; Lewis, RE; Prince, RA; Wiederhold, NP	1
Kamei, K; Watanabe, A	1
Kontoyiannis, DP; Lewis, RE; Lionakis, MS; Prince, RA; Wiederhold, NP	1
Abraham, SN; Balibar, CJ; Brooking, RM; Cramer, RA; Gamcsik, MP; Graybill, JR; Kirkpatrick, WR; Najvar, LK; Patterson, TF; Perfect, JR; Steinbach, WJ	1
Kavanagh, K; Kelly, J; Nagl, M; O'Keeffe, J; Reeves, EP	1
Borner, C; Ekert, PG; Galvez, EM; Kwon-Chung, J; Lobigs, M; Müllbacher, A; Müller, U; Pardo, J; Simon, MM; Urban, C; Wallich, R	1
Brakhage, AA; Geginat, G; Härtl, A; Heinekamp, T; Hof, H; Kupfahl, C; Ruppert, T	1
Andes, D; Balajee, SA; Bok, JW; Chung, D; Frisvad, JC; Keller, NP; Kirby, KA; Marr, KA; Nielsen, KF	1
André, K; Collet, X; Coméra, C; Galtier, P; Laffitte, J; Maridonneau-Parini, I	1
Fischer, G; Geginat, G; Haase, G; Hof, H; Kupfahl, C; Lass-Flörl, C; Michalka, A; Ruppert, T	1
Chang, YC; Gallin, JI; Galvez, EM; Kwon-Chung, KJ; Müllbacher, A; Nardone, G; Pardo, J; Simon, MM; Sugui, JA; Zarember, KA	1
Canestraro, M; Carulli, G; Galimberti, S; Komanduri, KV; Lewis, R; Orciuolo, E; Petrini, M; Stanzani, M	1
Eichner, RD; Müllbacher, A	1
Bratberg, AM; Chermette, R; Connole, MD; Debey, MC; Hasegawa, A; Lund, A; Padhye, AA; Pier, AC; Richard, JL	1
DeBey, MC; Richard, JL	1
Bauer, J; Gedek, B; Korbel, R	1
Müllbacher, A; Sutton, P; Waring, P	1
Dvorak, TJ; Richard, JL; Ross, PF	1
Bauer, J; Bott, A; Gareis, M; Gedek, B	1

Reviews

3 review(s) available for gliotoxin and Aspergillus Infection

Article	Year
Gliotoxin--bane or boon? Environmental microbiology, 2016, Volume: 18, Issue:4 Topics: Aspergillosis; Aspergillus fumigatus; Biological Control Agents; Biomarkers; Gliotoxin; Humans; Trichoderma; Virulence Factors	2016
Enemy of the (immunosuppressed) state: an update on the pathogenesis of Aspergillus fumigatus infection. British journal of haematology, 2010, Volume: 150, Issue:4 Topics: Adaptive Immunity; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Drug Discovery; Gliotoxin; Humans; Immune Evasion; Immunity, Mucosal; Immunocompromised Host; Stress, Physiological	2010
Aspergillus mycotoxins and their effect on the host. Medical mycology, 2005, Volume: 43 Suppl 1 Topics: Animals; Aspergillosis; Aspergillus fumigatus; Gliotoxin; Humans; Mycotoxins	2005

Other Studies

51 other study(ies) available for gliotoxin and Aspergillus Infection

Article	Year
DETECTION OF GLIOTOXIN BUT NOT BIS(METHYL)GLIOTOXIN IN PLASMA FROM BIRDS WITH CONFIRMED AND PROBABLE ASPERGILLOSIS. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2022, Volume: 53, Issue:1 Topics: Animals; Aspergillosis; Aspergillus; Aspergillus fumigatus; Birds; Gliotoxin; Rats; Rodent Diseases	2022
Dynamics of gliotoxin and bis(methylthio)gliotoxin production during the course of Aspergillus fumigatus infection. Medical mycology, 2022, Apr-27, Volume: 60, Issue:4 Topics: Animals; Aspergillosis; Aspergillus fumigatus; Gliotoxin; Virulence	2022
RgsA Attenuates the PKA Signaling, Stress Response, and Virulence in the Human Opportunistic Pathogen International journal of molecular sciences, 2019, Nov-11, Volume: 20, Issue:22 Topics: Animals; Aspergillosis; Aspergillus fumigatus; Cyclic AMP-Dependent Protein Kinases; Female; Fungal Proteins; Gliotoxin; Mice; Mice, Inbred ICR; Oxidative Stress; RGS Proteins; Signal Transduction; Transcriptome; Virulence	2019
Gliotoxin, a Known Virulence Factor in the Major Human Pathogen Aspergillus fumigatus, Is Also Biosynthesized by Its Nonpathogenic Relative mBio, 2020, 02-11, Volume: 11, Issue:1 Topics: Animals; Aspergillosis; Aspergillus; Aspergillus fumigatus; Fungal Proteins; Gene Expression Regulation, Fungal; Genomics; Gliotoxin; Moths; Multigene Family; Secondary Metabolism; Virulence; Virulence Factors	2020
The Aspergillus fumigatus transcription factor RglT is important for gliotoxin biosynthesis and self-protection, and virulence. PLoS pathogens, 2020, Volume: 16, Issue:7 Topics: Animals; Aspergillosis; Aspergillus fumigatus; Fungal Proteins; Gene Expression Regulation, Fungal; Gliotoxin; Mice; Oxidative Stress; Transcription Factors; Virulence	2020
Host immune status-specific production of gliotoxin and bis-methyl-gliotoxin during invasive aspergillosis in mice. Scientific reports, 2017, 09-08, Volume: 7, Issue:1 Topics: Animals; Aspergillosis; Aspergillus; Disease Models, Animal; Gliotoxin; Granulomatous Disease, Chronic; Host-Pathogen Interactions; Mice; Mice, Knockout; Neutropenia; Pulmonary Aspergillosis; Risk Factors; Steroids	2017
Selenate sensitivity of a laeA mutant is restored by overexpression of the bZIP protein MetR in Aspergillus fumigatus. Fungal genetics and biology : FG & B, 2018, Volume: 117 Topics: Alleles; Animals; Aspergillosis; Aspergillus fumigatus; Basic-Leucine Zipper Transcription Factors; Disease Models, Animal; DNA-Binding Proteins; Fungal Proteins; Gene Expression Regulation, Fungal; Gliotoxin; Methionine; Secondary Metabolism; Selenic Acid; Sequence Deletion; Transcription Factors; Transcriptome; Zebrafish	2018
Gliotoxin penetrates and impairs the integrity of the human blood-brain barrier in vitro. Mycotoxin research, 2018, Volume: 34, Issue:4 Topics: Aspergillosis; Aspergillus fumigatus; Blood-Brain Barrier; Cells, Cultured; Endothelial Cells; Gliotoxin; Humans; Induced Pluripotent Stem Cells; Models, Biological; Permeability	2018
Functional convergence of gliP and aspf1 in Aspergillus fumigatus pathogenicity. Virulence, 2018, Volume: 9, Issue:1 Topics: Allergens; Animals; Aspergillosis; Aspergillus fumigatus; Fungal Proteins; Gene Deletion; Gliotoxin; Humans; Male; Mice; Mice, Inbred BALB C; Virulence	2018
Reconstitution of Enzymatic Carbon-Sulfur Bond Formation Reveals Detoxification-Like Strategy in Fungal Toxin Biosynthesis. ACS chemical biology, 2018, 09-21, Volume: 13, Issue:9 Topics: Aspergillosis; Aspergillus fumigatus; Cytochrome P-450 Enzyme System; Diketopiperazines; Fungal Proteins; Gliotoxin; Glutathione Transferase; Humans; Hydroxylation; Secondary Metabolism; Virulence Factors	2018
Heterogeneity in Pathogenicity-related Properties and Stress Tolerance in Aspergillus fumigatus Clinical Isolates. Medical mycology journal, 2018, Volume: 59, Issue:4 Topics: Aspergillosis; Aspergillus fumigatus; Cluster Analysis; Gliotoxin; Humans; Osmotic Pressure; Oxidative Stress; Pancreatic Elastase	2018
Typing clinical and animal environment Aspergillus fumigatus gliotoxin producer strains isolated from Brazil by PCR-RFLP markers. Letters in applied microbiology, 2013, Volume: 57, Issue:6 Topics: Animals; Aspergillosis; Aspergillus fumigatus; Bacterial Typing Techniques; Base Sequence; Brazil; Cattle; Edible Grain; Female; Gliotoxin; Humans; Mastitis, Bovine; Molecular Sequence Data; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Silage	2013
Increased production of gliotoxin is related to the formation of biofilm by Aspergillus fumigatus: an immunological approach. Pathogens and disease, 2014, Volume: 70, Issue:3 Topics: Animals; Antibodies, Fungal; Antibody Specificity; Aspergillosis; Aspergillus fumigatus; Biofilms; Cell Line; Epithelial Cells; Female; Gliotoxin; Humans; Hyphae; Mice; Protein Binding; Respiratory Mucosa	2014
Development and validation of an HPLC-MS/MS method for the early diagnosis of aspergillosis. PloS one, 2014, Volume: 9, Issue:4 Topics: Aspergillosis; Chromatography, High Pressure Liquid; Gliotoxin; Humans; Liquid-Liquid Extraction; Quercetin; Reference Standards; Reproducibility of Results; Risk Factors; Solvents; Tandem Mass Spectrometry	2014
GliA in Aspergillus fumigatus is required for its tolerance to gliotoxin and affects the amount of extracellular and intracellular gliotoxin. Medical mycology, 2014, Volume: 52, Issue:5 Topics: Amino Acid Sequence; Animals; Aspergillosis; Aspergillus fumigatus; Cell Line; Fungal Proteins; Gene Deletion; Gliotoxin; Humans; Immunocompromised Host; Male; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Multigene Family; Mutation; Oxidoreductases; Sequence Alignment; Virulence; Virulence Factors	2014
Gliotoxin from Aspergillus fumigatus reverses epithelial to mesenchymal transition: implications in renal fibrosis. International journal of medical microbiology : IJMM, 2015, Volume: 305, Issue:1 Topics: Aspergillosis; Aspergillus fumigatus; Cell Differentiation; Cell Line; DNA, Fungal; Epithelial Cells; Fibrosis; Free Radical Scavengers; Gliotoxin; Humans; Kidney; Mesoderm; Molecular Sequence Data; Reactive Oxygen Species; Sequence Analysis, DNA	2015
Secondary metabolite profiles and antifungal drug susceptibility of Aspergillus fumigatus and closely related species, Aspergillus lentulus, Aspergillus udagawae, and Aspergillus viridinutans. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2015, Volume: 21, Issue:5 Topics: Antifungal Agents; Aspergillosis; Aspergillus; Aspergillus fumigatus; Gliotoxin; Humans; Itraconazole; Microbial Sensitivity Tests; Virulence Factors; Voriconazole	2015
Proteomic analyses reveal the key roles of BrlA and AbaA in biogenesis of gliotoxin in Aspergillus fumigatus. Biochemical and biophysical research communications, 2015, Jul-31, Volume: 463, Issue:3 Topics: Aspergillosis; Aspergillus fumigatus; Fungal Proteins; Gene Expression Regulation, Fungal; Gliotoxin; Humans; Mutation; Oxidoreductases; Proteomics; Trans-Activators; Transcription Factors	2015
Ecophysiology of environmental Aspergillus fumigatus and comparison with clinical strains on gliotoxin production and elastase activity. Letters in applied microbiology, 2016, Volume: 62, Issue:2 Topics: Aspergillosis; Aspergillus fumigatus; Elastin; Gliotoxin; Humans; Silage	2016
SCF Ubiquitin Ligase F-box Protein Fbx15 Controls Nuclear Co-repressor Localization, Stress Response and Virulence of the Human Pathogen Aspergillus fumigatus. PLoS pathogens, 2016, Volume: 12, Issue:9 Topics: Amino Acid Sequence; Animals; Aspergillosis; Aspergillus fumigatus; Co-Repressor Proteins; Cullin Proteins; Disease Models, Animal; F-Box Proteins; Female; Fungal Proteins; Gene Expression Regulation, Fungal; Gliotoxin; Humans; Mice; Mutation; Oxidative Stress; Phosphorylation; Protein Transport; SKP Cullin F-Box Protein Ligases; Ubiquitins; Virulence	2016
Aspergillosis, a Natural Infection in Poultry: Mycological and Molecular Characterization and Determination of Gliotoxin in Aspergillus fumigatus Isolates. Avian diseases, 2017, Volume: 61, Issue:1 Topics: Animals; Aspergillosis; Aspergillus fumigatus; Chickens; Gliotoxin; Lung; Poultry Diseases	2017
Aspergillus fumigatus inhibits angiogenesis through the production of gliotoxin and other secondary metabolites. Blood, 2009, Dec-17, Volume: 114, Issue:26 Topics: Animals; Aspergillosis; Aspergillus fumigatus; Cell Differentiation; Cell Movement; Endothelial Cells; Gene Expression; Gliotoxin; Humans; Mice; Mice, Inbred BALB C; Neovascularization, Physiologic; Umbilical Veins	2009
Development of an HPTLC-based diagnostic method for invasive aspergillosis. Biomedical chromatography : BMC, 2010, Volume: 24, Issue:8 Topics: Aspergillosis; Aspergillus; Chromatography, Thin Layer; Diagnostic Techniques and Procedures; Gliotoxin; Humans; Sensitivity and Specificity	2010
Self-protection against gliotoxin--a component of the gliotoxin biosynthetic cluster, GliT, completely protects Aspergillus fumigatus against exogenous gliotoxin. PLoS pathogens, 2010, Jun-10, Volume: 6, Issue:6 Topics: Amino Acid Sequence; Aspergillosis; Aspergillus fumigatus; Aspergillus nidulans; Blotting, Northern; Cloning, Molecular; Fungal Proteins; Gene Deletion; Genetic Complementation Test; Gliotoxin; Immunosuppressive Agents; Molecular Sequence Data; Multigene Family; Oxidoreductases; Proteomics; Saccharomyces cerevisiae; Virulence	2010
A nonredundant role for plasmacytoid dendritic cells in host defense against the human fungal pathogen Aspergillus fumigatus. Cell host & microbe, 2011, May-19, Volume: 9, Issue:5 Topics: Animals; Aspergillosis; Aspergillus fumigatus; Cell Survival; Cytokines; Dendritic Cells; Disease Models, Animal; Female; Gliotoxin; Humans; Hyphae; Lung; Male; Mice; Mice, Inbred C57BL	2011
Gliotoxin effects on fungal growth: mechanisms and exploitation. Fungal genetics and biology : FG & B, 2012, Volume: 49, Issue:4 Topics: Antifungal Agents; Ascomycota; Aspergillosis; Aspergillus; Aspergillus fumigatus; Biomarkers; Diamide; Down-Regulation; Fungal Proteins; Fusarium; Gene Expression Regulation, Fungal; Gliotoxin; Glutathione; Neurospora crassa; Oxidation-Reduction; Oxidoreductases; Saccharomyces cerevisiae; Sequence Deletion; Superoxide Dismutase; Up-Regulation	2012
Bis(methyl)gliotoxin proves to be a more stable and reliable marker for invasive aspergillosis than gliotoxin and suitable for use in diagnosis. Diagnostic microbiology and infectious disease, 2012, Volume: 73, Issue:1 Topics: Aspergillosis; Aspergillus fumigatus; Blood Chemical Analysis; Culture Media; Gliotoxin; Humans; Sensitivity and Specificity; Virulence Factors	2012
Aspergillus fumigatus activates thrombocytes by secretion of soluble compounds. The Journal of infectious diseases, 2013, Mar-01, Volume: 207, Issue:5 Topics: Animals; Aspergillosis; Aspergillus fumigatus; Blood Platelets; Culture Media, Conditioned; Disease Models, Animal; Female; Gliotoxin; Humans; Mice; Mice, Inbred BALB C; Platelet Aggregation; Serine Proteases	2013
Exposure of Aspergillus fumigatus to caspofungin results in the release, and de novo biosynthesis, of gliotoxin. Medical mycology, 2013, Volume: 51, Issue:2 Topics: Amino Acids; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Caspofungin; Echinocandins; Fungal Proteins; Gliotoxin; Hyphae; Immunosuppressive Agents; Lipopeptides; Oxidation-Reduction; Time Factors	2013
Detection of Aspergillus fumigatus mycotoxins: immunogen synthesis and immunoassay development. Journal of microbiological methods, 2004, Volume: 56, Issue:2 Topics: Animals; Antibodies, Fungal; Antibody Specificity; Aspergillosis; Aspergillus fumigatus; Blotting, Western; Enzyme-Linked Immunosorbent Assay; Female; Fusidic Acid; Gliotoxin; Mycotoxins; Rabbits; Serum Albumin, Bovine; Thyroglobulin	2004
Cytotoxic substances from Aspergillus fumigatus in oxygenated or poorly oxygenated environment. Mycopathologia, 2004, Volume: 158, Issue:1 Topics: Animals; Aspergillosis; Aspergillus fumigatus; Gas Chromatography-Mass Spectrometry; Gliotoxin; Humans; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Oxygen; Virulence	2004
Correlation between gliotoxin production and virulence of Aspergillus fumigatus in Galleria mellonella. Mycopathologia, 2004, Volume: 158, Issue:1 Topics: Animals; Aspergillosis; Aspergillus fumigatus; Aspergillus niger; Catalase; Gliotoxin; Humans; Moths; Pancreatic Elastase; Virulence	2004
Aspergillus fumigatus suppresses the human cellular immune response via gliotoxin-mediated apoptosis of monocytes. Blood, 2005, Mar-15, Volume: 105, Issue:6 Topics: Antigens, CD; Antigens, Fungal; Apoptosis; Aspergillosis; Aspergillus fumigatus; Caspase 3; Caspases; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; CD83 Antigen; Cells, Cultured; Cytomegalovirus; Dendritic Cells; Dose-Response Relationship, Immunologic; Enterotoxins; Gliotoxin; Humans; Immunoglobulins; Lymphocyte Activation; Membrane Glycoproteins; Monocytes	2005
Detection of gliotoxin in experimental and human aspergillosis. Infection and immunity, 2005, Volume: 73, Issue:1 Topics: Amphotericin B; Animals; Aspergillosis; Female; Gliotoxin; Humans; Lung; Mice	2005
Frequency and species distribution of gliotoxin-producing Aspergillus isolates recovered from patients at a tertiary-care cancer center. Journal of clinical microbiology, 2005, Volume: 43, Issue:12 Topics: Aspergillosis; Aspergillus; Culture Media; Gliotoxin; Humans; Neoplasms; Species Specificity	2005
Disruption of a nonribosomal peptide synthetase in Aspergillus fumigatus eliminates gliotoxin production. Eukaryotic cell, 2006, Volume: 5, Issue:6 Topics: Animals; Animals, Outbred Strains; Aspergillosis; Aspergillus fumigatus; Cell Degranulation; Cell Line, Tumor; Disease Models, Animal; Down-Regulation; Genome, Fungal; Gliotoxin; Immunocompromised Host; Male; Mast Cells; Mice; Multigene Family; Mutation; Neutropenia; Peptide Synthases; Phenotype; Rats; Virulence Factors	2006
Effect of N-chlorotaurine on Aspergillus, with particular reference to destruction of secreted gliotoxin. Journal of medical microbiology, 2006, Volume: 55, Issue:Pt 7 Topics: Antifungal Agents; Aspergillosis; Aspergillus; Gliotoxin; Humans; Microbial Sensitivity Tests; Quaternary Ammonium Compounds; Taurine	2006
The mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in mice. The Journal of cell biology, 2006, Aug-14, Volume: 174, Issue:4 Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Aspergillosis; Aspergillus fumigatus; bcl-2 Homologous Antagonist-Killer Protein; Caspase 3; Caspases; Cell Line, Transformed; Cytochromes c; Disease Models, Animal; Dose-Response Relationship, Drug; Fibroblasts; Gliotoxin; Immunity, Innate; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Membranes; Oxidative Stress; Reactive Oxygen Species; Virulence	2006
Deletion of the gliP gene of Aspergillus fumigatus results in loss of gliotoxin production but has no effect on virulence of the fungus in a low-dose mouse infection model. Molecular microbiology, 2006, Volume: 62, Issue:1 Topics: Animals; Aspergillosis; Aspergillus fumigatus; Blotting, Southern; Cell Line; Chromatography, High Pressure Liquid; Disease Models, Animal; Fungal Proteins; Gene Deletion; Gliotoxin; Mass Spectrometry; Mice; Mice, Inbred BALB C; Peptide Synthases; Virulence	2006
GliZ, a transcriptional regulator of gliotoxin biosynthesis, contributes to Aspergillus fumigatus virulence. Infection and immunity, 2006, Volume: 74, Issue:12 Topics: Animals; Apoptosis; Aspergillosis; Aspergillus fumigatus; Gene Deletion; Gene Expression Regulation, Fungal; Gliotoxin; Lung; Mice; Neutrophils; Transcription Factors; Virulence	2006
Gliotoxin from Aspergillus fumigatus affects phagocytosis and the organization of the actin cytoskeleton by distinct signalling pathways in human neutrophils. Microbes and infection, 2007, Volume: 9, Issue:1 Topics: Actins; Arachidonic Acid; Aspergillosis; Aspergillus fumigatus; Cyclic AMP; Cytoskeleton; Gliotoxin; Humans; NADPH Oxidases; Neutrophils; Phagocytosis; Signal Transduction	2007
Gliotoxin production by clinical and environmental Aspergillus fumigatus strains. International journal of medical microbiology : IJMM, 2008, Volume: 298, Issue:3-4 Topics: Animals; Aspergillosis; Aspergillus fumigatus; CD8-Positive T-Lymphocytes; Cell Line; Cell Line, Tumor; Cell Survival; Genes, Fungal; Gliotoxin; Humans; Macrophages; Mice	2008
Gliotoxin is a virulence factor of Aspergillus fumigatus: gliP deletion attenuates virulence in mice immunosuppressed with hydrocortisone. Eukaryotic cell, 2007, Volume: 6, Issue:9 Topics: Animals; Apoptosis; Aspergillosis; Aspergillus fumigatus; bcl-2 Homologous Antagonist-Killer Protein; Fungal Proteins; Gene Deletion; Gliotoxin; Humans; Hydrocortisone; Immunosuppression Therapy; Mice; Mice, Inbred BALB C; Neutrophils; Peptide Synthases; Respiratory Burst; Superoxides; Virulence; Virulence Factors	2007
Effects of Aspergillus fumigatus gliotoxin and methylprednisolone on human neutrophils: implications for the pathogenesis of invasive aspergillosis. Journal of leukocyte biology, 2007, Volume: 82, Issue:4 Topics: Anti-Inflammatory Agents; Apoptosis; Aspergillosis; Aspergillus fumigatus; Cell Degranulation; Cells, Cultured; Dendritic Cells; Gliotoxin; Humans; Immunocompromised Host; Inflammation; Methylprednisolone; Monocytes; Neutrophils; Peroxidase; Phagocytosis; Reactive Oxygen Species; Stem Cell Transplantation	2007
Hypothesis: Fungal toxins are involved in aspergillosis and AIDS. The Australian journal of experimental biology and medical science, 1984, Volume: 62 ( Pt 4) Topics: Acquired Immunodeficiency Syndrome; Aspergillosis; Aspergillus fumigatus; Gliotoxin; Humans; Immune Tolerance; Models, Biological; Mycotoxins	1984
Advances in veterinary mycology. Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology, 1994, Volume: 32 Suppl 1 Topics: Animals; Antigens, Fungal; Arthrodermataceae; Aspergillosis; Cat Diseases; Cats; Dermatomycoses; Dogs; Gliotoxin; Horse Diseases; Horses; Immunity; Opportunistic Infections; Poultry Diseases; Tinea; Turkeys	1994
Production of gliotoxin during the pathogenic state in turkey poults by Aspergillus fumigatus Fresenius. Mycopathologia, 1995, Volume: 129, Issue:2 Topics: Animals; Aspergillosis; Aspergillus fumigatus; Gliotoxin; Lung; Poultry Diseases; Species Specificity; Turkeys	1995
[Pathologico-anatomic and mycotoxicologic studies of aspergillosis in birds]. Tierarztliche Praxis, 1993, Volume: 21, Issue:2 Topics: Air Sacs; Animals; Aspergillosis; Aspergillus fumigatus; Bird Diseases; Birds; Gliotoxin; Lung; Lung Diseases, Fungal	1993
Exacerbation of invasive aspergillosis by the immunosuppressive fungal metabolite, gliotoxin. Immunology and cell biology, 1996, Volume: 74, Issue:4 Topics: Animals; Apoptosis; Aspergillosis; Aspergillus fumigatus; Cells, Cultured; Disease Models, Animal; Female; Gliotoxin; Immunosuppressive Agents; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Thymus Gland	1996
Natural occurrence of gliotoxin in turkeys infected with Aspergillus fumigatus, Fresenius. Mycopathologia, 1996, Volume: 134, Issue:3 Topics: Animals; Aspergillosis; Aspergillus fumigatus; Gliotoxin; Lung; Lung Diseases, Fungal; Poultry Diseases; Turkeys	1996
Isolation of a mycotoxin (gliotoxin) from a bovine udder infected with Aspergillus fumigatus. Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology, 1989, Volume: 27, Issue:1 Topics: Animals; Aspergillosis; Aspergillus fumigatus; Cattle; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Female; Gliotoxin; Mammary Glands, Animal; Mass Spectrometry; Mastitis, Bovine; Molecular Structure; Mycotoxins	1989