gliocladin-c and Leukemia-P388

gliocladin-c has been researched along with Leukemia-P388* in 1 studies

Other Studies

1 other study(ies) available for gliocladin-c and Leukemia-P388

Article	Year
Enantioselective organocatalytic construction of hexahydropyrroloindole by means of α-alkylation of aldehydes leading to the total synthesis of (+)-gliocladin C. Chemistry (Weinheim an der Bergstrasse, Germany), 2013, Mar-04, Volume: 19, Issue:10 12-step program: The combined use of cinchona alkaloid based amine and chiral phosphoric acid enabled the asymmetric alkylation reaction of 3-hydroxyoxindoles with aldehydes to give 3,3'-disubstituted oxindoles in excellent enantioselectivities, which allows for the enantioselective total synthesis of (+)-gliocladin C in 12 steps from 3-hydroxyoxindole with 19 % overall yield (see scheme; PMB = para-methoxybenzyl). Topics: Aldehydes; Alkaloids; Alkylation; Animals; Antineoplastic Agents; Catalysis; Cyclization; Leukemia P388; Molecular Structure; Piperazines; Pyrrolidinones; Stereoisomerism	2013

Article

Year

Enantioselective organocatalytic construction of hexahydropyrroloindole by means of α-alkylation of aldehydes leading to the total synthesis of (+)-gliocladin C.

Chemistry (Weinheim an der Bergstrasse, Germany), 2013, Mar-04, Volume: 19, Issue:10

12-step program: The combined use of cinchona alkaloid based amine and chiral phosphoric acid enabled the asymmetric alkylation reaction of 3-hydroxyoxindoles with aldehydes to give 3,3'-disubstituted oxindoles in excellent enantioselectivities, which allows for the enantioselective total synthesis of (+)-gliocladin C in 12 steps from 3-hydroxyoxindole with 19 % overall yield (see scheme; PMB = para-methoxybenzyl).

Topics: Aldehydes; Alkaloids; Alkylation; Animals; Antineoplastic Agents; Catalysis; Cyclization; Leukemia P388; Molecular Structure; Piperazines; Pyrrolidinones; Stereoisomerism

2013