Page last updated: 2024-10-27

glimepiride and Stroke

glimepiride has been researched along with Stroke in 5 studies

glimepiride: structure given in first source

Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)

Research Excerpts

ExcerptRelevanceReference
"Linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor in clinical use against type 2 diabetes."5.39The DPP-4 inhibitor linagliptin counteracts stroke in the normal and diabetic mouse brain: a comparison with glimepiride. ( Darlöf, E; Darsalia, V; Klein, T; Nyström, T; Olverling, A; Ortsäter, H; Patrone, C; Sjöholm, Å; Wolbert, P, 2013)
"Using nationwide administrative Danish registries, we followed all individuals without prior stroke or myocardial infarction who initiated metformin and an IS from 1997 through 2009."3.81Metformin in combination with various insulin secretagogues in type 2 diabetes and associated risk of cardiovascular morbidity and mortality--a retrospective nationwide study. ( Andersson, C; Fosbøl, EL; Gislason, G; Køber, L; Mogensen, UM; Scheller, NM; Schramm, TK; Torp-Pedersen, C; Vaag, A, 2015)
" We compared the effects of three SU medications and initial SU doses on adverse glycemic and cardiovascular events among NH residents."1.91Comparative safety of sulfonylureas among U.S. nursing home residents. ( Berry, SD; Hayes, KN; Munshi, MN; Riester, MR; Zullo, AR, 2023)
"Linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor in clinical use against type 2 diabetes."1.39The DPP-4 inhibitor linagliptin counteracts stroke in the normal and diabetic mouse brain: a comparison with glimepiride. ( Darlöf, E; Darsalia, V; Klein, T; Nyström, T; Olverling, A; Ortsäter, H; Patrone, C; Sjöholm, Å; Wolbert, P, 2013)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Zullo, AR2
Riester, MR2
Hayes, KN2
Munshi, MN2
Berry, SD2
Cho, EH1
Han, K1
Kim, B1
Lee, DH1
Shannon, RP1
Mogensen, UM1
Andersson, C1
Fosbøl, EL1
Schramm, TK1
Vaag, A1
Scheller, NM1
Torp-Pedersen, C1
Gislason, G1
Køber, L1
Darsalia, V1
Ortsäter, H1
Olverling, A1
Darlöf, E1
Wolbert, P1
Nyström, T1
Klein, T1
Sjöholm, Å1
Patrone, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Dipeptidyl-4 Inhibitors in Reducing Stroke Severity, From the Health Insurance Review and Assessment Service Database[NCT05817097]22,119 participants (Anticipated)Observational2023-08-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

5 other studies available for glimepiride and Stroke

ArticleYear
Comparative safety of sulfonylureas among U.S. nursing home residents.
    Journal of the American Geriatrics Society, 2023, Volume: 71, Issue:4

    Topics: Aged; Female; Glipizide; Glyburide; Humans; Hypoglycemia; Male; Medicare; Myocardial Infarction; Nur

2023
Comparative safety of sulfonylureas among U.S. nursing home residents.
    Journal of the American Geriatrics Society, 2023, Volume: 71, Issue:4

    Topics: Aged; Female; Glipizide; Glyburide; Humans; Hypoglycemia; Male; Medicare; Myocardial Infarction; Nur

2023
Comparative safety of sulfonylureas among U.S. nursing home residents.
    Journal of the American Geriatrics Society, 2023, Volume: 71, Issue:4

    Topics: Aged; Female; Glipizide; Glyburide; Humans; Hypoglycemia; Male; Medicare; Myocardial Infarction; Nur

2023
Comparative safety of sulfonylureas among U.S. nursing home residents.
    Journal of the American Geriatrics Society, 2023, Volume: 71, Issue:4

    Topics: Aged; Female; Glipizide; Glyburide; Humans; Hypoglycemia; Male; Medicare; Myocardial Infarction; Nur

2023
Gliclazide monotherapy increases risks of all-cause mortality and has similar risk of acute myocardial infarction and stroke with glimepiride monotherapy in Korean type 2 diabetes mellitus.
    Medicine, 2020, Jul-17, Volume: 99, Issue:29

    Topics: Adult; Aged; Asian People; Diabetes Mellitus, Type 2; Female; Gliclazide; Humans; Hypoglycemic Agent

2020
DPP-4 inhibition and neuroprotection: do mechanisms matter?
    Diabetes, 2013, Volume: 62, Issue:4

    Topics: Animals; Diabetes Mellitus, Experimental; Dipeptidyl-Peptidase IV Inhibitors; Hypoglycemic Agents; L

2013
Metformin in combination with various insulin secretagogues in type 2 diabetes and associated risk of cardiovascular morbidity and mortality--a retrospective nationwide study.
    Diabetes research and clinical practice, 2015, Volume: 107, Issue:1

    Topics: Aged; Carbamates; Cardiovascular Diseases; Denmark; Diabetes Mellitus, Type 2; Drug Therapy, Combina

2015
The DPP-4 inhibitor linagliptin counteracts stroke in the normal and diabetic mouse brain: a comparison with glimepiride.
    Diabetes, 2013, Volume: 62, Issue:4

    Topics: Animals; Diabetes Mellitus, Experimental; Dietary Fats; Dipeptidyl-Peptidase IV Inhibitors; Hypoglyc

2013