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glimepiride and Disease Models, Animal

glimepiride has been researched along with Disease Models, Animal in 11 studies

glimepiride: structure given in first source

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"The study of xeroderma pigmentosum has yielded unforeseen advances regarding how defects in the nucleotide excision repair pathway result in this devastating disease, but development of therapeutic strategies has trailed behind the mechanistic discoveries."2.61Novel therapeutic approaches to xeroderma pigmentosum. ( Glass, DA; Weon, JL, 2019)
"Tauopathy is a group of neurodegenerative diseases in which the pathogenesis processes are related to tau protein."1.72Glimepiride mitigates tauopathy and neuroinflammation in P301S transgenic mice: role of AKT/GSK3β signaling. ( Azab, SS; El-Desouky, S; Elsherbiny, DA; Salama, M; Zaki, MO, 2022)
"To generate a mouse model of type 2 diabetes mellitus (DM), male C57BL/6J mice were fed with high-fat diet and injected with streptozotocin."1.51Specific PERK inhibitors enhanced glucose-stimulated insulin secretion in a mouse model of type 2 diabetes. ( Ham, DS; Jung, HS; Kim, JW; Kim, MJ; Kim, MN; Min, SH; Park, KS; Yoon, KH, 2019)
" The present study concludes that bioavailability of SIL increases when co-administered chronically with GLIM in the management of DN animals, and the mechanism is supported by molecular modeling studies."1.42Does glimepiride alter the pharmacokinetics of sildenafil citrate in diabetic nephropathy animals: investigating mechanism of interaction by molecular modeling studies. ( Chandewar, A; Mazumder, PM; Timiri, AK; Tripathi, AS, 2015)
"Hyperglycemia is the main feature for the diagnosis of this disease."1.40Persistent impaired glucose metabolism in a zebrafish hyperglycemia model. ( Antonioli, R; Bogo, MR; Bonan, CD; Capiotti, KM; Da Silva, RS; Kist, LW, 2014)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's1 (9.09)29.6817
2010's4 (36.36)24.3611
2020's5 (45.45)2.80

Authors

AuthorsStudies
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Miura, M1
Tanaka, S1
Ikeda, M1
Kawakami, J1
Watanabe, H1
Namiki, N1
Uchida, S1
Zaki, MO1
El-Desouky, S1
Elsherbiny, DA1
Salama, M1
Azab, SS1
Oduola-Akande, MD1
Ishola, IO1
Olubodun-Obadun, TG1
Akande, AJ1
Adeyemi, OO1
Nasreen, W1
Sarker, S1
Sufian, MA1
Md Opo, FAD1
Shahriar, M1
Akhter, R1
Halim, MA1
Weon, JL1
Glass, DA1
Kim, MJ1
Kim, MN1
Min, SH1
Ham, DS1
Kim, JW1
Yoon, KH1
Park, KS1
Jung, HS1
Capiotti, KM1
Antonioli, R1
Kist, LW1
Bogo, MR1
Bonan, CD1
Da Silva, RS1
Tripathi, AS1
Timiri, AK1
Mazumder, PM1
Chandewar, A1
Ye, Y1
Lin, Y1
Perez-Polo, JR1
Birnbaum, Y1
Pan, J1
Chan, EK1
Yu, E1
Chen, J1
Schranz, V1
Charles, MA1

Reviews

1 review available for glimepiride and Disease Models, Animal

ArticleYear
Novel therapeutic approaches to xeroderma pigmentosum.
    The British journal of dermatology, 2019, Volume: 181, Issue:2

    Topics: Acetohexamide; Administration, Cutaneous; Animals; Caloric Restriction; Dermatology; Disease Models,

2019

Other Studies

10 other studies available for glimepiride and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Increased plasma drug concentration and decreased additional insulin secretion following oral administration of glimepiride in Spontaneously Diabetic Torii rats.
    Die Pharmazie, 2022, 01-03, Volume: 77, Issue:1

    Topics: Administration, Oral; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Humans; Insulin Se

2022
Glimepiride mitigates tauopathy and neuroinflammation in P301S transgenic mice: role of AKT/GSK3β signaling.
    Inflammopharmacology, 2022, Volume: 30, Issue:5

    Topics: Animals; Caspase 3; Diabetes Mellitus, Type 2; Disease Models, Animal; Glycogen Synthase Kinase 3 be

2022
Glimepiride Prevents 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Induced Dopamine Neurons Degeneration Through Attenuation of Glia Activation and Oxidative Stress in Mice.
    Neurotoxicity research, 2023, Volume: 41, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Diabetes Mellitus, Type 2; Disease Models, An

2023
A possible alternative therapy for type 2 diabetes using Myristica fragrans Houtt in combination with glimepiride: in vivo evaluation and in silico support.
    Zeitschrift fur Naturforschung. C, Journal of biosciences, 2020, Mar-26, Volume: 75, Issue:3-4

    Topics: Alloxan; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Therapy, Combination; Fema

2020
Specific PERK inhibitors enhanced glucose-stimulated insulin secretion in a mouse model of type 2 diabetes.
    Metabolism: clinical and experimental, 2019, Volume: 97

    Topics: Adenine; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; eIF-2 Kinase; Glucose; Hypergly

2019
Persistent impaired glucose metabolism in a zebrafish hyperglycemia model.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 2014, Volume: 171

    Topics: Animals; Disease Models, Animal; Eye Proteins; Glucose; Glycosylation; Hyperglycemia; Hypoglycemic A

2014
Does glimepiride alter the pharmacokinetics of sildenafil citrate in diabetic nephropathy animals: investigating mechanism of interaction by molecular modeling studies.
    Journal of molecular modeling, 2015, Volume: 21, Issue:10

    Topics: Animals; Blood Glucose; Cytochrome P-450 CYP2C9; Diabetic Nephropathies; Disease Models, Animal; Dru

2015
Oral glyburide, but not glimepiride, blocks the infarct-size limiting effects of pioglitazone.
    Cardiovascular drugs and therapy, 2008, Volume: 22, Issue:6

    Topics: Administration, Oral; Animals; Body Weight; Coronary Vessels; Data Interpretation, Statistical; Deca

2008
Prevention and cure of type 1 diabetes in the BB rat by islet allotransplantation and glimepiride treatment.
    Transplantation proceedings, 1995, Volume: 27, Issue:6

    Topics: Animals; Diabetes Mellitus, Type 1; Disease Models, Animal; Immunosuppressive Agents; Islets of Lang

1995