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glimepiride and Cardiac Failure

glimepiride has been researched along with Cardiac Failure in 9 studies

glimepiride: structure given in first source

Research Excerpts

ExcerptRelevanceReference
"To investigate the effect of left ventricular ejection fraction (LVEF) on the behavior of N-terminal pro-brain natriuretic peptide (NT-proBNP) levels in patients with heart failure and type 2 diabetes mellitus with the use of canagliflozin compared to glimepiride."9.69Influence of left ventricular ejection fraction on the reduction in N-terminal pro-brain natriuretic peptide by canagliflozin in patients with heart failure and type 2 diabetes: A sub analysis of the CANDLE trial. ( Eguchi, K; Kitada, S; Kodama, K; Node, K; Ohte, N; Seo, Y; Takeishi, Y; Tanaka, A; Teragawa, H; Yamada, T, 2023)
"Our findings suggest that 24 weeks of treatment with canagliflozin, relative to glimepiride, reduced WBC counts in patients with type 2 diabetes and heart failure."9.51Effect of canagliflozin on white blood cell counts in patients with type 2 diabetes and heart failure: A subanalysis of the randomized CANDLE trial. ( Imai, T; Matsunaga, K; Minamino, T; Nakamura, I; Node, K; Ozaki, Y; Sata, M; Shimabukuro, M; Tanaka, A, 2022)
"A total of 250 patients with type 2 diabetes who are drug-naïve or taking any anti-diabetic agents and suffering from chronic heart failure with a New York Heart Association classification I to III will be randomized centrally into either canagliflozin or glimepiride groups (1: 1) using the dynamic allocation method stratified by age (<65, ≥65 year), HbA1c level (<6."9.22Rationale and design of a randomized trial to test the safety and non-inferiority of canagliflozin in patients with diabetes with chronic heart failure: the CANDLE trial. ( Ako, J; Anzai, T; Eguchi, K; Inoue, T; Kitakaze, M; Murohara, T; Node, K; Oyama, J; Saito, Y; Sakata, Y; Sata, M; Sato, Y; Shimizu, W; Suzuki, M; Taguchi, I; Tanaka, A; Tomiyama, H; Ueda, S; Uematsu, M; Watada, H; Yamashina, A, 2016)
"This study was a post hoc analysis of the CANDLE trial (UMIN000017669), which compared the effect of 24 weeks of treatment with canagliflozin or glimepiride for changes in N-terminal pro-brain natriuretic peptide in patients with T2DM and chronic heart failure (CHF)."8.31Canagliflozin reduces proteinuria by targeting hyperinsulinaemia in diabetes patients with heart failure: A post hoc analysis of the CANDLE trial. ( Ajioka, M; Hiramitsu, S; Imai, T; Kadokami, T; Node, K; Shimabukuro, M; Suzuki, M; Takahashi, N; Tanaka, A; Yamaguchi, S, 2023)
"To investigate the effect of left ventricular ejection fraction (LVEF) on the behavior of N-terminal pro-brain natriuretic peptide (NT-proBNP) levels in patients with heart failure and type 2 diabetes mellitus with the use of canagliflozin compared to glimepiride."5.69Influence of left ventricular ejection fraction on the reduction in N-terminal pro-brain natriuretic peptide by canagliflozin in patients with heart failure and type 2 diabetes: A sub analysis of the CANDLE trial. ( Eguchi, K; Kitada, S; Kodama, K; Node, K; Ohte, N; Seo, Y; Takeishi, Y; Tanaka, A; Teragawa, H; Yamada, T, 2023)
"Our findings suggest that 24 weeks of treatment with canagliflozin, relative to glimepiride, reduced WBC counts in patients with type 2 diabetes and heart failure."5.51Effect of canagliflozin on white blood cell counts in patients with type 2 diabetes and heart failure: A subanalysis of the randomized CANDLE trial. ( Imai, T; Matsunaga, K; Minamino, T; Nakamura, I; Node, K; Ozaki, Y; Sata, M; Shimabukuro, M; Tanaka, A, 2022)
"A total of 250 patients with type 2 diabetes who are drug-naïve or taking any anti-diabetic agents and suffering from chronic heart failure with a New York Heart Association classification I to III will be randomized centrally into either canagliflozin or glimepiride groups (1: 1) using the dynamic allocation method stratified by age (<65, ≥65 year), HbA1c level (<6."5.22Rationale and design of a randomized trial to test the safety and non-inferiority of canagliflozin in patients with diabetes with chronic heart failure: the CANDLE trial. ( Ako, J; Anzai, T; Eguchi, K; Inoue, T; Kitakaze, M; Murohara, T; Node, K; Oyama, J; Saito, Y; Sakata, Y; Sata, M; Sato, Y; Shimizu, W; Suzuki, M; Taguchi, I; Tanaka, A; Tomiyama, H; Ueda, S; Uematsu, M; Watada, H; Yamashina, A, 2016)
"This study was a post hoc analysis of the CANDLE trial (UMIN000017669), which compared the effect of 24 weeks of treatment with canagliflozin or glimepiride for changes in N-terminal pro-brain natriuretic peptide in patients with T2DM and chronic heart failure (CHF)."4.31Canagliflozin reduces proteinuria by targeting hyperinsulinaemia in diabetes patients with heart failure: A post hoc analysis of the CANDLE trial. ( Ajioka, M; Hiramitsu, S; Imai, T; Kadokami, T; Node, K; Shimabukuro, M; Suzuki, M; Takahashi, N; Tanaka, A; Yamaguchi, S, 2023)
"In participants with type 2 diabetes, the incidences of microvascular complications and death were not materially different among the four treatment groups."3.11Glycemia Reduction in Type 2 Diabetes - Microvascular and Cardiovascular Outcomes. ( Bebu, I; Burch, HB; Buse, JB; Cherrington, AL; Fortmann, SP; Green, JB; Kahn, SE; Kirkman, MS; Krause-Steinrauf, H; Lachin, JM; Larkin, ME; Nathan, DM; Phillips, LS; Pop-Busui, R; Steffes, M; Tiktin, M; Tripputi, M; Wexler, DJ; Younes, N, 2022)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's2 (22.22)24.3611
2020's6 (66.67)2.80

Authors

AuthorsStudies
Tanaka, A6
Imai, T2
Shimabukuro, M2
Nakamura, I1
Matsunaga, K1
Ozaki, Y1
Minamino, T1
Sata, M2
Node, K6
Nathan, DM1
Lachin, JM1
Bebu, I1
Burch, HB1
Buse, JB1
Cherrington, AL1
Fortmann, SP1
Green, JB1
Kahn, SE1
Kirkman, MS1
Krause-Steinrauf, H1
Larkin, ME1
Phillips, LS1
Pop-Busui, R1
Steffes, M1
Tiktin, M1
Tripputi, M1
Wexler, DJ1
Younes, N1
Yamaguchi, S1
Hiramitsu, S1
Takahashi, N1
Kadokami, T1
Ajioka, M1
Suzuki, M2
Ohte, N2
Kitada, S2
Yamada, T2
Eguchi, K3
Teragawa, H2
Takeishi, Y2
Kodama, K2
Seo, Y2
Nakatani, D1
Dohi, T1
Hikoso, S1
Nanasato, M1
Shimizu, W2
Sakata, Y2
Zhao, C1
Jiang, X1
Peng, L1
Zhang, Y1
Li, H1
Zhang, Q1
Wang, Y1
Yang, F1
Wu, J1
Wen, Z1
He, Z1
Shen, J1
Chen, C1
Wang, DW1
Inoue, T1
Kitakaze, M1
Oyama, J1
Taguchi, I1
Watada, H1
Tomiyama, H1
Ako, J1
Anzai, T1
Uematsu, M1
Yamashina, A1
Saito, Y1
Sato, Y1
Ueda, S1
Murohara, T1
Andersson, C1
Gislason, GH1
Jørgensen, CH1
Hansen, PR1
Vaag, A1
Sørensen, R1
Mérie, C1
Olesen, JB1
Weeke, P1
Schmiegelow, M1
Norgaard, ML1
Køber, L1
Torp-Pedersen, C1
Skugor, M1
Siraj, ES1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study[NCT01794143]Phase 35,047 participants (Actual)Interventional2013-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for glimepiride and Cardiac Failure

ArticleYear
Effect of canagliflozin on white blood cell counts in patients with type 2 diabetes and heart failure: A subanalysis of the randomized CANDLE trial.
    Journal of diabetes investigation, 2022, Volume: 13, Issue:12

    Topics: Aged; Blood Glucose; Canagliflozin; Diabetes Mellitus, Type 2; Heart Failure; Humans; Hypoglycemic A

2022
Glycemia Reduction in Type 2 Diabetes - Microvascular and Cardiovascular Outcomes.
    The New England journal of medicine, 2022, 09-22, Volume: 387, Issue:12

    Topics: Albuminuria; Blood Glucose; Cardiovascular Diseases; Comparative Effectiveness Research; Diabetes Co

2022
Influence of left ventricular ejection fraction on the reduction in N-terminal pro-brain natriuretic peptide by canagliflozin in patients with heart failure and type 2 diabetes: A sub analysis of the CANDLE trial.
    Journal of cardiology, 2023, Volume: 81, Issue:6

    Topics: Biomarkers; Canagliflozin; Diabetes Mellitus, Type 2; Heart Failure; Humans; Natriuretic Peptide, Br

2023
Influence of left ventricular ejection fraction on the reduction in N-terminal pro-brain natriuretic peptide by canagliflozin in patients with heart failure and type 2 diabetes: A sub analysis of the CANDLE trial.
    Journal of cardiology, 2023, Volume: 81, Issue:6

    Topics: Biomarkers; Canagliflozin; Diabetes Mellitus, Type 2; Heart Failure; Humans; Natriuretic Peptide, Br

2023
Influence of left ventricular ejection fraction on the reduction in N-terminal pro-brain natriuretic peptide by canagliflozin in patients with heart failure and type 2 diabetes: A sub analysis of the CANDLE trial.
    Journal of cardiology, 2023, Volume: 81, Issue:6

    Topics: Biomarkers; Canagliflozin; Diabetes Mellitus, Type 2; Heart Failure; Humans; Natriuretic Peptide, Br

2023
Influence of left ventricular ejection fraction on the reduction in N-terminal pro-brain natriuretic peptide by canagliflozin in patients with heart failure and type 2 diabetes: A sub analysis of the CANDLE trial.
    Journal of cardiology, 2023, Volume: 81, Issue:6

    Topics: Biomarkers; Canagliflozin; Diabetes Mellitus, Type 2; Heart Failure; Humans; Natriuretic Peptide, Br

2023
Relationship Between Canagliflozin, Sodium Glucose Cotransporter 2 Inhibitor, and Hematopoietic Effects in Patients With Diabetes and Mild Heart Failure: Results From the CANDLE Trial.
    Journal of cardiovascular pharmacology, 2023, 07-01, Volume: 82, Issue:1

    Topics: Canagliflozin; Diabetes Mellitus, Type 2; Glycated Hemoglobin; Heart Failure; Humans; Hypoglycemic A

2023
Rationale and design of a randomized trial to test the safety and non-inferiority of canagliflozin in patients with diabetes with chronic heart failure: the CANDLE trial.
    Cardiovascular diabetology, 2016, Apr-04, Volume: 15

    Topics: Adult; Aged; Aged, 80 and over; Benzhydryl Compounds; Blood Glucose; Blood Pressure; Canagliflozin;

2016

Other Studies

4 other studies available for glimepiride and Cardiac Failure

ArticleYear
Canagliflozin reduces proteinuria by targeting hyperinsulinaemia in diabetes patients with heart failure: A post hoc analysis of the CANDLE trial.
    Diabetes, obesity & metabolism, 2023, Volume: 25, Issue:2

    Topics: Canagliflozin; Chronic Disease; Diabetes Mellitus, Type 2; Heart Failure; Humans; Hyperinsulinism; H

2023
Glimepiride, a novel soluble epoxide hydrolase inhibitor, protects against heart failure via increasing epoxyeicosatrienoic acids.
    Journal of molecular and cellular cardiology, 2023, Volume: 185

    Topics: Animals; Eicosanoids; Epoxide Hydrolases; Heart; Heart Failure; Humans; Mice

2023
Comparable long-term mortality risk associated with individual sulfonylureas in diabetes patients with heart failure.
    Diabetes research and clinical practice, 2011, Volume: 94, Issue:1

    Topics: Aged; Aged, 80 and over; Diabetes Mellitus; Female; Glipizide; Glyburide; Heart Failure; Humans; Hyp

2011
A diabetic woman with worsening heart failure, hunger, and tremor.
    Cleveland Clinic journal of medicine, 2003, Volume: 70, Issue:10

    Topics: Diabetes Mellitus, Type 2; Diabetic Angiopathies; Gastrointestinal Agents; Heart Failure; Humans; Hy

2003