Page last updated: 2024-10-27

gliclazide and Stroke

gliclazide has been researched along with Stroke in 7 studies

Gliclazide: An oral sulfonylurea hypoglycemic agent which stimulates insulin secretion.

Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)

Research Excerpts

ExcerptRelevanceReference
"Using nationwide administrative Danish registries, we followed all individuals without prior stroke or myocardial infarction who initiated metformin and an IS from 1997 through 2009."3.81Metformin in combination with various insulin secretagogues in type 2 diabetes and associated risk of cardiovascular morbidity and mortality--a retrospective nationwide study. ( Andersson, C; Fosbøl, EL; Gislason, G; Køber, L; Mogensen, UM; Scheller, NM; Schramm, TK; Torp-Pedersen, C; Vaag, A, 2015)
"In patients with type 2 diabetes, moderate alcohol use, particularly wine consumption, is associated with reduced risks of cardiovascular events and all-cause mortality."2.79The relationship between alcohol consumption and vascular complications and mortality in individuals with type 2 diabetes. ( Blomster, JI; Chalmers, J; Chow, CK; Harrap, S; Hillis, GS; Li, Q; Mancia, G; Neal, B; Patel, A; Poulter, N; Williams, B; Woodward, M; Zoungas, S, 2014)
"The incidence of congestive cardiac failure was similar with pioglitazone (12/1857) and non-pioglitazone (10/1856) treatments."2.42Cardiovascular effects of treatment of type 2 diabetes with pioglitazone, metformin and gliclazide. ( Belcher, G; Edwards, G; Goh, KL; Lambert, C; Valbuena, M, 2004)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's4 (57.14)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Cho, EH1
Han, K1
Kim, B1
Lee, DH1
Douros, A1
Yin, H1
Yu, OHY1
Filion, KB1
Azoulay, L1
Suissa, S1
Blomster, JI1
Zoungas, S3
Chalmers, J3
Li, Q2
Chow, CK1
Woodward, M3
Mancia, G2
Poulter, N2
Williams, B1
Harrap, S2
Neal, B2
Patel, A3
Hillis, GS1
Mogensen, UM1
Andersson, C1
Fosbøl, EL1
Schramm, TK1
Vaag, A1
Scheller, NM1
Torp-Pedersen, C1
Gislason, G1
Køber, L1
Mohammedi, K1
Marre, M1
de Galan, BE1
Anderson, C1
Dufouil, C1
Pillai, A1
Cooper, M1
Grobbee, DE1
Hackett, M1
Hamet, P1
Heller, SR1
Lisheng, L1
MacMahon, S1
Pan, CY1
Travert, F1
Belcher, G1
Lambert, C1
Goh, KL1
Edwards, G1
Valbuena, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
ADVANCE - Action in Diabetes and Vascular Disease: Preterax and Diamicron - MR Controlled Evaluation[NCT00145925]Phase 311,140 participants (Actual)Interventional2001-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for gliclazide and Stroke

ArticleYear
Cardiovascular effects of treatment of type 2 diabetes with pioglitazone, metformin and gliclazide.
    International journal of clinical practice, 2004, Volume: 58, Issue:9

    Topics: Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Double-Blind Method; Female; Glicl

2004

Trials

2 trials available for gliclazide and Stroke

ArticleYear
The relationship between alcohol consumption and vascular complications and mortality in individuals with type 2 diabetes.
    Diabetes care, 2014, Volume: 37, Issue:5

    Topics: Aged; Alcohol Drinking; Antihypertensive Agents; Coronary Disease; Diabetes Mellitus, Type 2; Diabet

2014
Absence of Peripheral Pulses and Risk of Major Vascular Outcomes in Patients With Type 2 Diabetes.
    Diabetes care, 2016, Volume: 39, Issue:12

    Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diagnostic Techniques, Cardiovascular; Disea

2016

Other Studies

4 other studies available for gliclazide and Stroke

ArticleYear
Gliclazide monotherapy increases risks of all-cause mortality and has similar risk of acute myocardial infarction and stroke with glimepiride monotherapy in Korean type 2 diabetes mellitus.
    Medicine, 2020, Jul-17, Volume: 99, Issue:29

    Topics: Adult; Aged; Asian People; Diabetes Mellitus, Type 2; Female; Gliclazide; Humans; Hypoglycemic Agent

2020
Pharmacologic Differences of Sulfonylureas and the Risk of Adverse Cardiovascular and Hypoglycemic Events.
    Diabetes care, 2017, Volume: 40, Issue:11

    Topics: Aged; Aged, 80 and over; Body Mass Index; Cardiovascular Diseases; Cohort Studies; Diabetes Mellitus

2017
Metformin in combination with various insulin secretagogues in type 2 diabetes and associated risk of cardiovascular morbidity and mortality--a retrospective nationwide study.
    Diabetes research and clinical practice, 2015, Volume: 107, Issue:1

    Topics: Aged; Carbamates; Cardiovascular Diseases; Denmark; Diabetes Mellitus, Type 2; Drug Therapy, Combina

2015
Cognitive function and risks of cardiovascular disease and hypoglycaemia in patients with type 2 diabetes: the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) trial.
    Diabetologia, 2009, Volume: 52, Issue:11

    Topics: Aged; Antihypertensive Agents; Cognition; Cognition Disorders; Diabetes Mellitus, Type 2; Diabetic A

2009