gliclazide has been researched along with Myocardial Ischemia in 6 studies
Gliclazide: An oral sulfonylurea hypoglycemic agent which stimulates insulin secretion.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "In older patients with type 2 diabetes hospitalized for IHD, prior use of gliclazide, glyburide, or repaglinide appears to be associated with a similar risk of adverse cardiovascular sequelae." | 1.42 | Comparative cardiovascular safety of insulin secretagogues following hospitalization for ischemic heart disease among type 2 diabetes patients: a cohort study. ( Abdelmoneim, AS; Huang, Y; Light, P; Qiu, W; Simpson, SH, 2015) |
| "Gliclazide or saline was given q12 h for 48 h to rats received isoprenaline." | 1.38 | Blockers of sulfonylureas receptor 1 subunits may lead to cardiac protection against isoprenaline-induced injury in obese rats. ( Bao, Y; Shuyuan, L; Sun, X; Yang, W; Yerong, Y, 2012) |
| "3." | 1.29 | Chronic gliclazide treatment affects basal and post-ischemic cardiac function in diabetic rats. ( Mimura, G; Murakami, K; Nagamine, F; Oshiro, K; Shimabukuro, M, 1994) |
| "Glimepiride is a new sulfonylurea." | 1.29 | Cardiovascular effects of conventional sulfonylureas and glimepiride. ( Geisen, K; Krause, E; Papp, JG; Végh, A, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, Y | 1 |
| Abdelmoneim, AS | 1 |
| Light, P | 1 |
| Qiu, W | 1 |
| Simpson, SH | 1 |
| Bao, Y | 1 |
| Sun, X | 1 |
| Yerong, Y | 1 |
| Shuyuan, L | 1 |
| Yang, W | 1 |
| Xue, J | 1 |
| Liu, M | 1 |
| Chen, JH | 1 |
| Shimabukuro, M | 1 |
| Nagamine, F | 1 |
| Murakami, K | 1 |
| Oshiro, K | 1 |
| Mimura, G | 1 |
| Geisen, K | 1 |
| Végh, A | 1 |
| Krause, E | 1 |
| Papp, JG | 1 |
| Jennings, PE | 1 |
| Belch, JJ | 1 |
2 trials available for gliclazide and Myocardial Ischemia
| Article | Year |
|---|---|
Clinical observation on effect of Kaixin capsule in treating 40 patients with diabetic myocardial ischemia.
Topics: Adult; Blood Glucose; Diabetes Complications; Diabetes Mellitus, Type 2; Drugs, Chinese Herbal; Elec | 2006 |
[Free radical scavenging activity of sulfonylureas: a clinical assessment of the effectiveness of gliclazide].
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Follow-Up Studies; Free Radical Scavengers; G | 2001 |
4 other studies available for gliclazide and Myocardial Ischemia
| Article | Year |
|---|---|
Comparative cardiovascular safety of insulin secretagogues following hospitalization for ischemic heart disease among type 2 diabetes patients: a cohort study.
Topics: Aged; Aged, 80 and over; Alberta; Blue Cross Blue Shield Insurance Plans; Carbamates; Cardiovascular | 2015 |
Blockers of sulfonylureas receptor 1 subunits may lead to cardiac protection against isoprenaline-induced injury in obese rats.
Topics: Animals; ATP-Binding Cassette Transporters; Cell Size; Gene Expression Regulation; Gliclazide; Heart | 2012 |
Chronic gliclazide treatment affects basal and post-ischemic cardiac function in diabetic rats.
Topics: Adenosine Triphosphate; Animals; Diabetes Mellitus, Experimental; Gliclazide; Heart; Lactates; Lacti | 1994 |
Cardiovascular effects of conventional sulfonylureas and glimepiride.
Topics: Animals; Blood Pressure; Cardiovascular System; Coronary Vessels; Diabetes Mellitus, Experimental; D | 1996 |