gliclazide has been researched along with Ischemia in 4 studies
Gliclazide: An oral sulfonylurea hypoglycemic agent which stimulates insulin secretion.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the dynamics of the intracellular Ca2+ concentration ([Ca2+]i) during retinal ischemia in rats with streptozotocin (STZ)-induced diabetes and the effect of gliclazide, a sulfonylurea with a potent free-radical scavenging activity on ischemia-induced [Ca2+]i dynamics." | 7.73 | Gliclazide attenuates the intracellular Ca2+ changes induced in vitro by ischemia in the retinal slices of rats with streptozotocin-induced diabetes. ( Harata, N; Kinukawa, J; Shimura, M; Tamai, M, 2005) |
| "In type 2 diabetic patients, the vasodilating response to forearm ischemia was the same whether patients were treated with diet treatment alone or with glibenclamide or glimepiride at blood glucose-lowering equipotent closes." | 5.09 | Sulfonylurea treatment of type 2 diabetic patients does not reduce the vasodilator response to ischemia. ( Brunelli, C; Cordera, R; Cordone, S; Olivotti, L; Rossettin, P; Schiavo, M; Spallarossa, P, 2001) |
| "The aim of this study was to assess the potential beneficial effects of gliclazide and other sulphonylureas on ischemia-induced retinal neovascularization." | 3.74 | Comparisons between the beneficial effects of different sulphonylurea treatments on ischemia-induced retinal neovascularization. ( Kimura, T; Kita, M; Suzuma, K; Takagi, H; Watanabe, D; Yoshimura, N, 2007) |
| "To investigate the dynamics of the intracellular Ca2+ concentration ([Ca2+]i) during retinal ischemia in rats with streptozotocin (STZ)-induced diabetes and the effect of gliclazide, a sulfonylurea with a potent free-radical scavenging activity on ischemia-induced [Ca2+]i dynamics." | 3.73 | Gliclazide attenuates the intracellular Ca2+ changes induced in vitro by ischemia in the retinal slices of rats with streptozotocin-induced diabetes. ( Harata, N; Kinukawa, J; Shimura, M; Tamai, M, 2005) |
| " After dosing glibenclamide induced a significant (P = 0." | 2.71 | Forearm vascular reactivity is differentially influenced by gliclazide and glibenclamide in chronically treated type 2 diabetic patients. ( Boes, U; Wascher, TC, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wascher, TC | 1 |
| Boes, U | 1 |
| Kinukawa, J | 1 |
| Shimura, M | 1 |
| Harata, N | 1 |
| Tamai, M | 1 |
| Kimura, T | 1 |
| Takagi, H | 1 |
| Suzuma, K | 1 |
| Kita, M | 1 |
| Watanabe, D | 1 |
| Yoshimura, N | 1 |
| Spallarossa, P | 1 |
| Schiavo, M | 1 |
| Rossettin, P | 1 |
| Cordone, S | 1 |
| Olivotti, L | 1 |
| Cordera, R | 1 |
| Brunelli, C | 1 |
2 trials available for gliclazide and Ischemia
| Article | Year |
|---|---|
Forearm vascular reactivity is differentially influenced by gliclazide and glibenclamide in chronically treated type 2 diabetic patients.
Topics: Adult; Analysis of Variance; Cross-Over Studies; Diabetes Mellitus, Type 2; Dose-Response Relationsh | 2005 |
Sulfonylurea treatment of type 2 diabetic patients does not reduce the vasodilator response to ischemia.
Topics: Aged; Aged, 80 and over; Blood Pressure; Brachial Artery; Diabetes Mellitus, Type 2; Diet, Diabetic; | 2001 |
2 other studies available for gliclazide and Ischemia
| Article | Year |
|---|---|
Gliclazide attenuates the intracellular Ca2+ changes induced in vitro by ischemia in the retinal slices of rats with streptozotocin-induced diabetes.
Topics: Aniline Compounds; Animals; Calcium; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Gliclazi | 2005 |
Comparisons between the beneficial effects of different sulphonylurea treatments on ischemia-induced retinal neovascularization.
Topics: Acetylcysteine; Animals; Blood Glucose; Female; Gliclazide; Glyburide; Ischemia; Mice; Oxidative Str | 2007 |