Page last updated: 2024-10-27

gliclazide and Innate Inflammatory Response

gliclazide has been researched along with Innate Inflammatory Response in 5 studies

Gliclazide: An oral sulfonylurea hypoglycemic agent which stimulates insulin secretion.

Research Excerpts

ExcerptRelevanceReference
"A diet-induced non-alcoholic fatty liver disease (NAFLD) model causing obesity in rodents was used to examine whether sitagliptin and gliclazide therapies have similar protective effects on pathological liver change."8.12Sitagliptin Is More Effective Than Gliclazide in Preventing  Pro-Fibrotic and Pro-Inflammatory Changes in a Rodent Model of Diet-Induced Non-Alcoholic Fatty Liver Disease. ( Gorrell, MD; McLennan, SV; Ren, J; Twigg, SM; Wang, X; Yee, C, 2022)
"A diet-induced non-alcoholic fatty liver disease (NAFLD) model causing obesity in rodents was used to examine whether sitagliptin and gliclazide therapies have similar protective effects on pathological liver change."4.12Sitagliptin Is More Effective Than Gliclazide in Preventing  Pro-Fibrotic and Pro-Inflammatory Changes in a Rodent Model of Diet-Induced Non-Alcoholic Fatty Liver Disease. ( Gorrell, MD; McLennan, SV; Ren, J; Twigg, SM; Wang, X; Yee, C, 2022)
"Treatment with empagliflozin showed a significant amelioration of behavioral/neurological functions and histopathological changes observed in brain tissues of hyperglycemic rats subjected to cerebral I/R injury."1.56Empagliflozin attenuates transient cerebral ischemia/reperfusion injury in hyperglycemic rats via repressing oxidative-inflammatory-apoptotic pathway. ( Abdel-Latif, RG; Amin, EF; Rifaai, RA, 2020)
"Treatment with gliclazide alone decreased serum glucose, total cholesterol, triglycerides, malondialdehyde, tumor necrosis factor-alpha and nuclear factor kappa-Beta while increased serum C-peptide, superoxide dismutase, reduced glutathione and adiponectin levels."1.56New combination therapy of gliclazide and quercetin for protection against STZ-induced diabetic rats. ( Abdelkader, NF; Badawi, MA; Eitah, HE; Gamaleldin, AA; Kenawy, SA; Maklad, YA, 2020)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's3 (60.00)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Ren, J1
Wang, X1
Yee, C1
Gorrell, MD1
McLennan, SV1
Twigg, SM1
Amin, EF1
Rifaai, RA1
Abdel-Latif, RG1
Abdelkader, NF1
Eitah, HE1
Maklad, YA1
Gamaleldin, AA1
Badawi, MA1
Kenawy, SA1
Räkel, A1
Renier, G1
Roussin, A1
Buithieu, J1
Mamputu, JC1
Serri, O1

Trials

1 trial available for gliclazide and Innate Inflammatory Response

ArticleYear
Beneficial effects of gliclazide modified release compared with glibenclamide on endothelial activation and low-grade inflammation in patients with type 2 diabetes.
    Diabetes, obesity & metabolism, 2007, Volume: 9, Issue:1

    Topics: Adult; Aged; Diabetes Mellitus, Type 2; Double-Blind Method; Endothelium, Vascular; Female; Gliclazi

2007

Other Studies

4 other studies available for gliclazide and Innate Inflammatory Response

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Sitagliptin Is More Effective Than Gliclazide in Preventing  Pro-Fibrotic and Pro-Inflammatory Changes in a Rodent Model of Diet-Induced Non-Alcoholic Fatty Liver Disease.
    Molecules (Basel, Switzerland), 2022, Jan-22, Volume: 27, Issue:3

    Topics: Animals; Diet, High-Fat; Gliclazide; Hypoglycemic Agents; Inflammation; Liver Cirrhosis; Male; Mice;

2022
Empagliflozin attenuates transient cerebral ischemia/reperfusion injury in hyperglycemic rats via repressing oxidative-inflammatory-apoptotic pathway.
    Fundamental & clinical pharmacology, 2020, Volume: 34, Issue:5

    Topics: Animals; Apoptosis; Benzhydryl Compounds; Disease Models, Animal; Gliclazide; Glucosides; Hyperglyce

2020
New combination therapy of gliclazide and quercetin for protection against STZ-induced diabetic rats.
    Life sciences, 2020, Apr-15, Volume: 247

    Topics: Animals; Blood Glucose; C-Peptide; Cholesterol; Diabetes Mellitus, Experimental; Drug Therapy, Combi

2020