gliclazide has been researched along with Benign Neoplasms in 8 studies
Gliclazide: An oral sulfonylurea hypoglycemic agent which stimulates insulin secretion.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gliclazide has been suspected to be associated with a lower obesity-related cancer risk; however, current evidence is limited by important methodologic shortcomings." | 7.96 | Is Gliclazide Associated with a Lower Obesity-Related Cancer Risk Compared to Other Sulfonylureas? A Long-term Prospective Cohort Study. ( de Bock, GH; Du, J; Groenier, KH; Kleefstra, N; Landman, GWD; Schrijnders, D, 2020) |
| "Gliclazide has been suspected to be associated with a lower obesity-related cancer risk; however, current evidence is limited by important methodologic shortcomings." | 3.96 | Is Gliclazide Associated with a Lower Obesity-Related Cancer Risk Compared to Other Sulfonylureas? A Long-term Prospective Cohort Study. ( de Bock, GH; Du, J; Groenier, KH; Kleefstra, N; Landman, GWD; Schrijnders, D, 2020) |
| "Treatment with glibenclamide could be associated with higher mortality for cardiovascular diseases and malignancies, in comparison with gliclazide." | 3.74 | Are sulphonylureas all the same? A cohort study on cardiovascular and cancer-related mortality. ( Balzi, D; Barchielli, A; Buiatti, E; Lamanna, C; Mannucci, E; Marchionni, N; Masotti, G; Monami, M, 2007) |
| "Type 2 diabetes has been associated with an increased risk of cancer." | 2.76 | Intensive glucose control and risk of cancer in patients with type 2 diabetes. ( Chalmers, J; De Bruin, ML; Grobbee, DE; Kengne, AP; Knol, MJ; Leufkens, HG; Patel, A; Stefansdottir, G; Woodward, M; Zoungas, S, 2011) |
| "Hyperglycaemia is a risk factor for cancer and some sulphonylureas have anti-oxidant properties." | 1.36 | Use of sulphonylurea and cancer in type 2 diabetes-The Hong Kong Diabetes Registry. ( Chan, JC; Chow, CC; Ko, GT; Kong, AP; Luk, AO; Ma, RC; Ng, VW; Ozaki, R; So, WY; Tong, PC; Yang, X; Yu, LW, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 1 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Liu, Y | 2 |
| He, S | 1 |
| Chen, Y | 1 |
| Feng, F | 1 |
| Liu, W | 1 |
| Guo, Q | 1 |
| Zhao, L | 1 |
| Sun, H | 1 |
| Du, J | 1 |
| Kleefstra, N | 1 |
| Schrijnders, D | 1 |
| Groenier, KH | 1 |
| de Bock, GH | 1 |
| Landman, GWD | 1 |
| Bo, S | 1 |
| Castiglione, A | 1 |
| Ghigo, E | 1 |
| Gentile, L | 1 |
| Durazzo, M | 1 |
| Cavallo-Perin, P | 1 |
| Ciccone, G | 1 |
| Monami, M | 2 |
| Lamanna, C | 2 |
| Balzi, D | 2 |
| Marchionni, N | 2 |
| Mannucci, E | 2 |
| Yang, X | 1 |
| So, WY | 1 |
| Ma, RC | 1 |
| Yu, LW | 1 |
| Ko, GT | 1 |
| Kong, AP | 1 |
| Ng, VW | 1 |
| Luk, AO | 1 |
| Ozaki, R | 1 |
| Tong, PC | 1 |
| Chow, CC | 1 |
| Chan, JC | 1 |
| Stefansdottir, G | 1 |
| Zoungas, S | 1 |
| Chalmers, J | 1 |
| Kengne, AP | 1 |
| Knol, MJ | 1 |
| Leufkens, HG | 1 |
| Patel, A | 1 |
| Woodward, M | 1 |
| Grobbee, DE | 1 |
| De Bruin, ML | 1 |
| Barchielli, A | 1 |
| Masotti, G | 1 |
| Buiatti, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| ADVANCE - Action in Diabetes and Vascular Disease: Preterax and Diamicron - MR Controlled Evaluation[NCT00145925] | Phase 3 | 11,140 participants (Actual) | Interventional | 2001-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for gliclazide and Benign Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
Overview of AKR1C3: Inhibitor Achievements and Disease Insights.
Topics: Aldo-Keto Reductase Family 1 Member C3; Antineoplastic Agents; Binding Sites; Cell Proliferation; Cl | 2020 |
1 trial available for gliclazide and Benign Neoplasms
| Article | Year |
|---|---|
Intensive glucose control and risk of cancer in patients with type 2 diabetes.
Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Female; Gliclazide; Humans; Hypoglycemic Agents; Ins | 2011 |
5 other studies available for gliclazide and Benign Neoplasms
| Article | Year |
|---|---|
Is Gliclazide Associated with a Lower Obesity-Related Cancer Risk Compared to Other Sulfonylureas? A Long-term Prospective Cohort Study.
Topics: Cohort Studies; Female; Gliclazide; Humans; Hypoglycemic Agents; Incidence; Male; Neoplasms; Obesity | 2020 |
Mortality outcomes of different sulphonylurea drugs: the results of a 14-year cohort study of type 2 diabetic patients.
Topics: Adult; Aged; Cardiovascular Diseases; Cause of Death; Cohort Studies; Confounding Factors, Epidemiol | 2013 |
Sulphonylureas and cancer: a case-control study.
Topics: Aged; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Gliclazide; Glybur | 2009 |
Use of sulphonylurea and cancer in type 2 diabetes-The Hong Kong Diabetes Registry.
Topics: Aged; Asian People; Cohort Studies; Diabetes Mellitus, Type 2; Female; Gliclazide; Glipizide; Glybur | 2010 |
Are sulphonylureas all the same? A cohort study on cardiovascular and cancer-related mortality.
Topics: Aged; Cardiovascular Diseases; Cohort Studies; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; | 2007 |