gliclazide has been researched along with Aging in 3 studies
Gliclazide: An oral sulfonylurea hypoglycemic agent which stimulates insulin secretion.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The combined treatment of deprenyl and gliclazide may contribute to the control of the physiopathological mechanisms underlying both the process of aging and type 2 diabetes by reducing oxidant stress and DNA damage, improving antioxidant status, and increasing survival, and may have implications for further clinical studies." | 3.73 | Effect of I-deprenyl and gliclazide on oxidant stress/antioxidant status and dna damage in a diabetic rat model. ( Alper, G; Caglayan, O; Duman, E; Irer, S; Yilmaz, C, 2005) |
| " Patients were randomly assigned to sulphonylurea increased up to its maximum dosage (1st group) or to addition of metformin (2nd group)." | 2.69 | Poorly controlled elderly Type 2 diabetic patients: the effects of increasing sulphonylurea dosages or adding metformin. ( Ambrosi, F; Carle, F; Filipponi, P; Gregorio, F; Manfrini, S; Merante, D; Testa, R; Velussi, M, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alper, G | 1 |
| Irer, S | 1 |
| Duman, E | 1 |
| Caglayan, O | 1 |
| Yilmaz, C | 1 |
| Iwamoto, Y | 1 |
| Akanuma, Y | 1 |
| Kosaka, J | 1 |
| Gregorio, F | 1 |
| Ambrosi, F | 1 |
| Manfrini, S | 1 |
| Velussi, M | 1 |
| Carle, F | 1 |
| Testa, R | 1 |
| Merante, D | 1 |
| Filipponi, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Metformin Glycinate Compared to Metformin Hydrochloride on the Progression of Type 2 Diabetes[NCT04943692] | Phase 3 | 500 participants (Anticipated) | Interventional | 2021-08-31 | Suspended (stopped due to Administrative decision of the investigation direction) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for gliclazide and Aging
| Article | Year |
|---|---|
Poorly controlled elderly Type 2 diabetic patients: the effects of increasing sulphonylurea dosages or adding metformin.
Topics: Aged; Aging; Antithrombin III; Blood Glucose; Blood Platelets; Cholesterol, HDL; Cholesterol, LDL; D | 1999 |
2 other studies available for gliclazide and Aging
| Article | Year |
|---|---|
Effect of I-deprenyl and gliclazide on oxidant stress/antioxidant status and dna damage in a diabetic rat model.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aging; Animals; Antioxidants; Blood Glucose; Body Weight; Deoxyguanosin | 2005 |
[Effect of insulin and gliclazide administration on insulin action and insulin binding in aged rat adipocytes].
Topics: Adipose Tissue; Aging; Animals; Gliclazide; Insulin; Male; Rats; Receptor, Insulin; Sulfonylurea Com | 1982 |